97349 ⎘
Fusion polypeptide containing domain for protein-protein interaction containing domain for transcriptional activaation, e.g. VP16
Sub-classes:NOVEL RECEPTORS FOR TRANSCRIPTION REGULATION
#2COMPOSITIONS AND METHODS FOR SELECTIVE GENE REGULATION
#3TRANS-SPLICING MOLECULES
#4ENGINEERED GENETIC INCOMPATIBILITY IN PLANTS
#5CRISPR/CAS9-BASED REPRESSORS FOR SILENCING GENE TARGETS IN VIVO AND METHODS OF USE
#6EPIGENETIC MODULATION OF GENOMIC TARGETS TO CONTROL EXPRESSION OF PWS-ASSOCIATED GENES
#7RNA-GUIDED NUCLEASES AND DNA BINDING PROTEINS
#8CRISPR-Cas Enzymes with Enhanced On-Target Activity
#9FUSION MOLECULES OF RATIONALLY-DESIGNED DNA-BINDING PROTEINS AND EFFECTOR DOMAINS
#10NOVEL SYSTEM FOR THE DETECTION AND QUANTIFICATION OF ANTI-AAV NEUTRALIZING ANTIBODIES
#11COMPOSITIONS AND METHODS FOR TREATING CANCER BY INCREASING EXPRESSION OF OBSCN-AS1 LONG-NONCODING RNA
#12MODIFIED CASCADE RIBONUCLEOPROTEINS AND USES THEREOF
#13TRANSCRIPTION ACTIVATORS AND PROGRAMMABLE TRANSCRIPTION ENGINEERING
#14METHOD FOR ROBUST CONTROL OF GENE EXPRESSION
#15MODIFIED CASCADE RIBONUCLEOPROTEINS AND USES THEREOF
#16RECOMBINANT NEWCASTLE DISEASE VIRUSES AND IMMUNOGENIC COMPOSITIONS FOR USE IN IMMUNIZING AGAINST SARS-COV-2 OMICRON VARIANT
#17MODIFIED CASCADE RIBONUCLEOPROTEINS AND USES THEREOF
#18COMPOSITIONS, SYSTEMS, AND METHODS FOR ACTIVATING AND SILENCING GENE EXPRESSION
#19Induction of IL-15/IL-15RA Expression in Immune Cells
#20ACTIVATION OF NONCODING HOST GENE LOCI
#21METHODS AND COMPOSITIONS FOR THE TREATMENT OF RARE DISEASES
#22Compositions And Methods For Regulating ZNF865
#23ENDOGENOUS GENE REGULATION TO TREAT NEUROLOGICAL DISORDERS AND DISEASES
#24De novo designed sequence-specific DNA binding proteins
#25TREATMENT OF FRAGILE X SYNDROME
#26ENGINEERED DNA BINDING PROTEINS
#27TRANS-SPLICING MOLECULES
#28CRISPR/CAS9-BASED REPRESSORS FOR SILENCING GENE TARGETS IN VIVO AND METHODS OF USE
#29FUSION MOLECULES OF RATIONALLY-DESIGNED DNA-BINDING PROTEINS AND EFFECTOR DOMAINS
#30SYNTHETIC INTERMEMBRANE PROTEOLYSIS RECEPTORS FOR CUSTOM ANTIGEN-INDUCED TRANSCRIPTIONAL REGULATION
#31MODIFIED CASCADE RIBONUCLEOPROTEINS AND USES THEREOF
#32Nucleic Acids That Manipulate Immune Pathways
#33Method for robust control of gene expression
#34Engineered CRISPR-Cas9 nucleases with Altered PAM Specificity
#35COMPOUNDS AND METHODS TO TREAT CYSTIC FIBROSIS
#36METHODS AND COMPOSITIONS FOR TREATING HUNTINGTON'S DISEASE
#37Engineered CRISPR-Cas9 nucleases with altered PAM specificity
#38BILE SALTS BACTOSENSOR AND USE THEREOF FOR DIAGNOSTIC AND THERAPEUTIC PURPOSES
#39NOVEL CELLULAR RECEPTORS AND USES THEREOF
#40CANINE AND FELINE INDUCIBLE EXPRESSION CONSTRUCTS FOR GENE THERAPY APPLICATIONS
#41PLANT TRANSACTIVATION INTERACTION MOTIFS AND USES THEREOF
#42ZINC FINGER PROTEIN TRANSCRIPTION FACTORS FOR REPRESSING TAU EXPRESSION
#43NON-VIRAL TRANSCRIPTION ACTIVATION DOMAINS AND METHODS AND USES RELATED THERETO
#44USE OF BRAIN-SPECIFIC ANTIGENS TO HOME, BLOCK AND DELIVER CELL-BASED TREATMENTS TO THE BRAIN
#45Engineered CRISPR-Cas9 nucleases with Altered PAM Specificity
#46METHODS AND COMPOSITIONS FOR MODULATING PD1
#47Methods and compositions for reducing the immunogenicity of chimeric notch receptors
#48METHODS AND COMPOSITIONS FOR REDUCING THE IMMUNOGENICITY OF CHIMERIC NOTCH RECEPTORS
#49RECEPTORS WITH HETEROLOGOUS TRANSMEMBRANE DOMAIN
#50Compositions and Methods for Modulation of Gene Expression
#51CELL PERMEABLE PROTEINS FOR GENOME ENGINEERING
#52DNA-BINDING DOMAIN TRANSACTIVATORS AND USES THEREOF
#53Engineered CRISPR-Cas9 nucleases with altered PAM specificity
#54Engineered CRISPR-Cas9 nucleases with altered PAM specificity
#55COMPOSITIONS AND METHODS FOR SELECTIVE GENE REGULATION
#56Zinc Finger Protein-Superoxide Dismutase Fusion Protein With Cell Membrane Penetrating Property
#57CAGED-DEGRON-BASED MOLECULAR FEEDBACK CIRCUITS AND METHODS OF USING THE SAME
#58SYSTEMS AND METHODS FOR METABOLIC ENGINEERING
#59SELECTION BY MEANS OF ARTIFICIAL TRANSACTIVATORS
#60RNA-GUIDED NUCLEASES AND DNA BINDING PROTEINS
#61Engineered CRISPR-Cas9 Nucleases
#62NOVEL TRANSCRIPTION ACTIVATOR
#63CRISPR-Cas enzymes with enhanced on-target activity
#64Cellular receptors and uses thereof
#65METHODS FOR DETERMINING THE PRESENCE OR RISK OF DEVELOPING FACIOSCAPULOHUMERAL DYSTROPHY (FSHD)
#66Methods to create chemically-induced dimerizing protein systems for regulation of cellular events
#67Tunable transcriptional regulators responsive to environmental triggers
#68POLYPEPTIDE, DERIVATIVES THEREOF, AND APPLICATION THEREOF IN PREPARATION OF DRUGS HAVING RESISTANCE TO PULMONARY FIBROSIS
#69Modified cascade ribonucleoproteins and uses thereof
#70Method for robust control of gene expression
#71Trans-splicing molecules
#72Plant transactivation interaction motifs and uses thereof
#73Methods and compositions for treating Huntington's Disease
#74RNA-GUIDED GENE EDITING AND GENE REGULATION
#75Systems, methods, and compositions for targeted nucleic acid editing
#76RNA-GUIDED GENE EDITING AND GENE REGULATION
#77Engineered CRISPR-Cas9 nucleases with altered PAM specificity
#78Engineered CRISPR-Cas9 nucleases with altered PAM specificity
#79Engineered DNA binding proteins
#80GENOME ENGINEERING WITH CRISPR-CAS SYSTEMS IN EUKARYOTES
#81TREATMENT OF FRAGILE X SYNDROME
#82Modified cascade ribonucleoproteins and uses thereof
#83Systems, methods, and compositions for targeted nucleic acid editing
#84NUCLEIC ACIDS THAT MANIPULATE IMMUNE PATHWAYS
#85Engineered CRISPR-Cas9 nucleases
#86Engineered CRISPR-Cas9 nucleases with altered PAM specificity
#87Engineered CRISPR-Cas9 Nucleases
#88Modified cascade ribonucleoproteins and uses thereof
#89Methods and compositions for treating Huntington's disease
#90Use of a HIV derived accessory protein for the reactivation of latent HIV
#91Plant transactivation interaction motifs and uses thereof
#92Hippo pathway bioluminescent biosensor
#93SYNTHETIC TRANSCRIPTIONAL REGULATOR COMPOSITIONS AND METHODS
#94Methods and compositions for treating Huntington's disease
#95Engineered CRISPR-Cas9 nucleases with altered PAM specificity
#96Methods and compositions for reducing the immunogenicity of chimeric notch receptors
#97Methods and compositions for modulating PD1
#98RNA-guided gene editing and gene regulation
#99Methods to create chemically-induced dimerizing protein systems for regulation of cellular events
#100Engineered CRISPR-Cas9 nucleases with altered PAM specificity
#101Engineered CRISPR-Cas9 nucleases
#102Methods and compositions for treating trinucleotide repeat disorders
#103COMPOSITION AND METHODS FOR REGULATING INHIBITORY INTERACTIONS IN GENETICALLY ENGINEERED CELLS
#104Modified cascade ribonucleoproteins and uses thereof
#105FUSION MOLECULES OF RATIONALLY-DESIGNED DNA-BINDING PROTEINS AND EFFECTOR DOMAINS
#106Engineered CRISPR-Cas9 nucleases with altered PAM specificity
#107METHODS AND PRODUCTS FOR INCREASING FRATAXIN LEVELS AND USES THEREOF
#108INDUCED PLURIPOTENT STEM CELLS
#109REGULATION OF ENDOGENOUS GENE EXPRESSION IN CELLS USING ZINC FINGER PROTEINS
#110Blue light-inducible system for gene expression
#111Tale transcriptional activators
#112Methods and compositions for treating Huntington's Disease
#113Fusion protein for inducing pluripotent stem cells and application method thereof
#114Engineered CRISPR-Cas9 nucleases with altered PAM specificity
#115Engineered CRISPR-CAS9 nucleases with altered PAM specificity
#116Engineered CRISPR-CAS9 nucleases with altered PAM specificity
#117Methods and compositions for modulating PD1
#118RNA-guided gene editing and gene regulation
#119Modified cascade ribonucleoproteins and uses thereof
#120VP16-CREB fusion gene
#121Methods and compositions for treating trinucleotide repeat disorders
#122ARTIFICIAL TRANSCRIPTION FACTORS FOR THE TREATMENT OF DISEASES CAUSED BY OPA1 HAPLOINSUFFICIENCY
#123Tale transcriptional activators
#124Methods and compositions for treating Huntington's Disease
#125Methods and compositions for prevention or treatment of a disease
#126Fusion Molecules of Rationally-Designed DNA-Binding Proteins and Effector Domains
#127Target molecules for transcriptional control systems
#128Methods and compositions for treating Huntington's disease
#129Blue-light inducible system for gene expression
#130Methods and products for increasing frataxin levels and uses thereof
#131Process, vectors and engineered cell lines for enhanced large-scale transfection
#132Methods and compositions for modulating PD1
#133Transducible polypeptides for modifying metabolism
#134Methods for alleviating facioscapulohumeral dystrophy (FSHD) by N siRNA molecule inhibiting the expression of DUX4-FL
#135Methods and compositions for treating Huntington's Disease
#136Plant transactivation interaction motifs and uses thereof
#137Induced pluripotent stem cells
#138Compositions and methods of treating head and neck cancer
#139Polypeptides having nucleic acid binding activity and compositions and methods for nucleic acid amplification
#140Ecdysone receptor-based inducible gene expression system
#141Regulation of endogenous gene expression in cells using zinc finger proteins
#142Transducible polypeptides for modifying metabolism
#143Quantitative assay for membrane association of proteins
#144Genetically Intact Induced Pluripotent Cells Or Transdifferentiated Cells And Methods For The Production Thereof
#145Methods and compositions for treating neuropathic and neurodegenerative conditions
#146Method of expression of foreign gene in plant induced by chemical substance
#147Regulation of endogenous gene expression in cells using zinc finger proteins
#148Genetically intact induced pluripotent cells or transdifferentiated cells and methods for the production thereof
#149Methods and compositions for modulating PD1
#150Soluble notch-based substrates for gamma secretase and methods and compositions for using same
#151Engineered zinc finger proteins for treating trinucleotide repeat disorders
#152Novel Ecdysone Receptor-Based Inducible Gene Expression System
#153Ecdysone receptor-based inducible gene expression system
#154Multiple domain proteins
#155Process, vectors and engineered cell lines for enhanced large-scale transfection
#156REGULATED TRANSCRIPTION OF TARGETED GENES AND OTHER BIOLOGICAL EVENTS
#157Targeted modification of chromatin structure
#158Regulated apoptosis
#159Alteration of tumor growth using zinc finger proteins
#160LexA-based chemical-inducible gene expression system for use in transgenic animals
#161Regulation of endogenous gene expression in cells using zinc finger proteins
#162Methods and compositions for treating neuropathic and neurodegenerative conditions
#163DNA for eukaryotic expression of CymR
#164Polypeptides Having Nucleic Acid Binding Activity and Compositions and Methods For Nucleic Acid Amplification
#165COMPOSITIONS FOR REPROGRAMMING A CELL AND USES THEREFOR
#166CANCER-SPECIFIC PROMOTERS
#167Interaction trap systems for detecting protein interactions
#168TRANSDUCIBLE POLYPEPTIDES FOR MODIFYING METABOLISM
#169Compositions of pamps and Listeria monocytogenes and methods of use
#170Regulated transcription of targeted genes and other biological events
#171METHODS FOR SCREENING INSECTICIDES
#172Targeted modification of chromatin structure
#173Anti-angiogenic methods and compositions
#174SP16 protein
#175Anti-angiogenic methods and compositions
#176Ecdysone receptor-based inducible gene expression system
#177Anti-angiogenic methods and compositions
#178Generation of potent dominant negative transcriptional inhibitors
#179Conditional gene vectors regulated in
#180Nucleic acids encoding chimeric interleukin-6 soluble receptor/ligand protein, analogs thereof and uses thereof
#181Ecdysone receptor-based inducible gene expression system
#182In vivo odorant receptor systems and their uses
#183Steroid-activated nuclear receptors and uses therefor
#184Regulation of endogenous gene expression in cells using zinc finger proteins
#185Repressing endogenous CCR5 gene expression in cells using engineered zinc finger proteins
#186Polypeptides having nucleic acid binding activity and compositions and methods for nucleic acid amplification
#187Anti-angiogenic methods and compositions
#188Targeted modification of chromatin structure
#189Compositions and methods related to modified retroviral vectors for restricted, site specific integration
#190Compositions and methods for inducing gene expression
#191Regulated transcription of targeted genes and other biological events
#192Regulation of endogenous gene expression in cells using zinc finger proteins
#193Compositions and methods for protein production
#194Gene transcription and ionizing radiation: methods and compositions
#195Regulated apoptosis
#196Methods and compositions for treating neuropathic and neurodegenerative conditions
#197Method of screening insulin resistance inproving drug
#198Regulation of endogenous gene expression in cells using zinc finger proteins
#199Surrogate cell-based system and method for assaying the activity of hepatitis C virus NS3 protease
#200Variant Tat proteins and methods for use thereof
#201Regulation of endogenous gene expression in cells using zinc finger proteins
#202Rapidly degrading GFP-fusion proteins and methods of use
#203Regulation of endogenous gene expression in cells using zinc finger proteins
#204Zinc finger protein derivatives and methods therefor
#205Method of screening for gamma-secretase activity