109026 ⎘
Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor; Recombinant DNA-technology; Processes for the isolation, preparation or purification of DNA or RNA; Mutagenizing nucleic acids mutagenesis by gene assembly, e.g. assembly by oligonucleotide extension PCR
A LOOPABLE TRANSLATOR FOR THE SYNTHESIS OF REPETITIVE PROTEINS
#2CLONING AND EXPRESSION SYSTEM FOR T-CELL RECEPTORS
#3PREPARATION OF LONG READ NUCLEIC ACID LIBRARIES
#4PREPARATION OF LONG READ NUCLEIC ACID LIBRARIES
#5PREPARATION OF LONG READ NUCLEIC ACID LIBRARIES
#6METHOD FOR PRODUCING DOUBLE STRANDED DNA
#7PREPARATION OF LONG READ NUCLEIC ACID LIBRARIES
#8METHODS FOR SEAMLESS NUCLEIC ACID ASSEMBLY
#9METHOD FOR CONSTRUCTING gE GENE-DELETED PSEUDORABIES VIRUS STRAIN USING ADENINE BASE EDITOR AND USE THEREOF
#10RNA-Guided Targeting of Genetic and Epigenomic Regulatory Proteins to Specific Genomic Loci
#11COMPOSITIONS AND METHODS FOR POLYNUCLEOTIDE ASSEMBLY
#12Systems for nucleic acid-based data storage
#13OPTIMIZED NUCLEIC ACID ANTIBODY CONSTRUCTS
#14RNA REPLICON FOR IMPROVING GENE EXPRESSION AND USE THEREOF
#15METHOD FOR GENERATING DOUBLE-STRANDED NUCLEIC ACID
#16IN VIVO DNA ASSEMBLY AND ANALYSIS
#17NOVEL PROCESSES FOR THE PRODUCTION OF OLIGONUCLEOTIDES
#18Increasing Specificity for RNA-Guided Genome Editing
#19NUCLEASE-MEDIATED DNA ASSEMBLY
#20SYNTHETIC GENOME
#21ELECTROPORATION, DEVELOPMENTALLY-ACTIVATED CELLS, PLURIPOTENT-LIKE CELLS, CELL REPROGRAMMING AND REGENERATIVE MEDICINE
#22PRIMERS AND ASSAYS FOR LINKING REGIONS USING POLYMERASES
#23SYNTHETIC GENOME
#24METHODS AND POLYNUCLEOTIDES FOR AMPLIFYING A TARGET POLYNUCLEOTIDE
#25METHODS OF GENE ASSEMBLY USING DNAZYMES AND USE IN DNA DATA STORAGE
#26Systems for nucleic acid-based data storage
#27Using Truncated Guide RNAs (tru-gRNAs) to Increase Specificity for RNA-Guided Genome Editing
#28COMPOSITIONS AND METHODS FOR HIGH FIDELITY ASSEMBLY OF NUCLEIC ACIDS
#29METHYLATION-MEDIATED ADAPTER REMOVAL ON NUCLEIC ACID SEQUENCES
#30SYNTHETIC GENOME
#31ELECTROPORATION, DEVELOPMENTALLY-ACTIVATED CELLS, PLURIPOTENT-LIKE CELLS, CELL REPROGRAMMING AND REGENERATIVE MEDICINE
#32Global gene regulators (GGR) as vaccine candidates against paratuberculosis
#33DEVELOPMENT OF A NEW ENGINEERED TOBACCO ETCH VIRUS (TEV) PROTEASE ACTIVABLE IN THE CYTOSOL OR SECRETORY PATHWAY
#34INTRA-GENOMIC HOMOLOGOUS RECOMBINATION
#35Method For Constructing Gene Mutation Library
#36BLOCKING-TYPE CHAIN POLYMERIZATION AMPLIFICATION REACTION BASED IN VITRO FAST SYNTHESIS OF MEDIUM AND HIGH-COPY DNA REPETITIVE SEQUENCE
#37Method for synthesis of polynucleotides using a diverse library of oligonucleotides
#38COMPOSITIONS AND METHODS FOR TEMPLATE-FREE DOUBLE STRANDED GEOMETRIC ENZYMATIC NUCLEIC ACID SYNTHESIS
#39METHODS AND COMPOSITIONS FOR ENRICHMENT OF TARGET POLYNUCLEOTIDES
#40Methods for seamless nucleic acid assembly
#41A METHOD FOR DEVELOPMENTALLY ACTIVATING A CELL
#42SYNTHETIC GENOME
#43METHOD
#44Gene site saturation mutagenesis (GSSM) method
#45BARCODE-BASED NUCLEIC ACID SEQUENCE ASSEMBLY
#46MULTIPLEX ASSEMBLY OF NUCLEIC ACID MOLECULES
#47HIGH EFFICIENCY, SMALL VOLUME NUCLEIC ACID SYNTHESIS
#48Method of generating targeted DNA libraries
#49Methods and Uses of Introducing Mutations into Genetic Material for Genome Assembly
#50A LIBRARY OF POLYNUCLEOTIDES
#51COMPOSITIONS, METHODS AND APPARATUS FOR OLIGONUCLEOTIDES SYNTHESIS
#52RNA-guided targeting of genetic and epigenomic regulatory proteins to specific genomic loci
#53COMPOSITIONS AND METHODS FOR SYNTHETIC GENE ASSEMBLY
#54Methods for nucleic acid assembly and high throughput sequencing
#55High efficiency, small volume nucleic acid synthesis
#56Compositions and methods for high fidelity assembly of nucleic acids
#57COMPOSITIONS AND METHODS FOR MULTIPLEX NUCLEIC ACIDS SYNTHESIS
#58RANDOM NUCLEOTIDE MUTATION FOR NUCLEOTIDE TEMPLATE COUNTING AND ASSEMBLY
#59METHODS FOR ASSEMBLING DNA MOLECULES
#60Methods and devices for nucleic acids synthesis
#61Methods of gene assembly and their use in DNA data storage
#62ASSEMBLY OF HIGH FIDELITY POLYNUCLEOTIDES
#63Yeast Cell Extract Assisted Construction of DNA Molecules
#64Scalable method for isolation and sequence-verification of oligonucleotides from complex libraries
#65Global gene regulators (GGR) as vaccine candidates against
#66Method for knocking out N-myristoyltransferase (NMT) gene from
#67Optimized nucleic acid antibody constructs encoding anti-respiratory syncytial virus (RSV) antibodies
#68Gene Synthesis by Self-Assembly of Small Oligonucleotide Building Blocks
#69ASSEMBLY AND ERROR REDUCTION OF SYNTHETIC GENES FROM OLIGONUCLEOTIDES
#70HIGH THROUGHPUT ASSEMBLY OF NUCLEIC ACID MOLECULES
#71VARIANT NUCLEOTIDE LIBRARY
#72Increasing specificity for RNA-guided genome editing
#73Barcode-based nucleic acid sequence assembly
#74Methods of gene assembly and their use in DNA data storage
#75Microfluidic lab-on-a-chip for gene synthesis
#76LIBRARIES OF NUCLEIC ACIDS AND METHODS FOR MAKING THE SAME
#77Methods and compositions for enrichment of target polynucleotides
#78SELF-DIVERSIFYING SYSTEMS AND METHODS OF USE THEREOF
#79Primers and assays for linking regions using polymerases
#80HIGH EFFICIENCY, SMALL VOLUME NUCLEIC ACID SYNTHESIS
#81Methods for seamless nucleic acid assembly
#82Method for synthesis of polynucleotides using a diverse library of oligonucleotides
#83METHOD FOR RAPID GENERATION OF AN ATTENUATED RNA VIRUS
#84Error detection during hybridisation of target double-stranded nucleic acid
#85Using RNA-guided FokI nucleases (RFNs) to increase specificity for RNA-guided genome editing
#86DNA PRODUCTION METHOD AND DNA FRAGMENT-JOINING KIT
#87Nuclease-mediated DNA assembly
#88Methods for nucleic acid assembly and high throughput sequencing
#89Methods and devices for nucleic acids synthesis
#90High efficiency, small volume nucleic acid synthesis
#91Global gene regulators (GGR) as vaccine candidates against paratuberculosis
#92Methods and uses of introducing mutations into genetic material for genome assembly
#93Using truncated guide RNAs (tru-gRNAs) to increase specificity for RNA-guided genome editing
#94IN VITRO DNA WRITING FOR INFORMATION STORAGE
#95Electroporation, developmentally-activated cells, pluripotent-like cells, cell reprogramming and regenerative medicine
#96Compositions, methods and apparatus for oligonucleotides synthesis
#97Methods and polynucleotides for amplifying a target polynucleotide
#98Mutagenizing intracellular nucleic acids
#99PCR-based method for generating multisite saturation mutagenic DNA libraries
#100RNA-guided targeting of genetic and epigenomic regulatory proteins to specific genomic loci
#101COMPOSITIONS AND METHODS FOR SYNTHETIC GENE ASSEMBLY
#102SCARLESS DNA ASSEMBLY AND GENOME EDITING USING CRISPR/CPF1 AND DNA LIGASE
#103Antibody like protein
#104Methods of De Novo Assembly of Barcoded Genomic DNA Fragments
#105Compositions and methods for multiplex nucleic acids synthesis
#106Nuclease-mediated DNA assembly
#107PEG-MEDIATED ASSEMBLY OF NUCLEIC ACID MOLECULES
#108Gene Synthesis by Self-Assembly of Small Oligonucleotide Building Blocks
#109GUIDE RNA ASSEMBLY VECTOR
#110Bacteriophage engineering via semi-synthesis
#111Method for producing DNA vectors from molecular bricks containing sequences of interest
#112Cloning and expression system for T-cell receptors
#113COMPOSITIONS AND METHODS FOR SYNTHESIS OF HIGH FIDELITY OLIGONUCLEOTIDES
#114METHODS AND COMPOSITIONS FOR CLONING INTO LARGE VECTORS
#115METHOD FOR ASSEMBLY OF POLYNUCLEIC ACID SEQUENCES USING PHOSPHOROTHIOATE BONDS WITHIN LINKER OLIGOS
#116Methods for seamless nucleic acid assembly
#117Fusion polymerase and method for using the same
#118Method for fabricating two-dimensional protein crystals
#119Using RNA-guided FokI nucleases (RFNs) to increase specificity for RNA-guided genome editing
#120MULTIPLEX PAIRWISE ASSEMBLY OF DNA OLIGONUCLEOTIDES
#121Assembly of high fidelity polynucleotides
#122COMPOSITIONS AND METHODS FOR NUCLEIC ACID ASSEMBLY
#123Comprehensive in vitro reporting of cleavage events by sequencing (CIRCLE-seq)
#124Compositions and methods for polynucleotide assembly
#125Methods and compositions for enrichment of target polynucleotides
#126Synthon Formation
#127Increasing specificity for RNA-guided genome editing
#128Method for rapid generation of an attenuated RNA virus
#129RNA-mediated gene assembly from DNA oligonucleotides
#130Methods for assembling DNA molecules
#131Synthetic auxotrophs with ligand dependent essential genes for biosafety
#132GENE MUTATION DETECTION METHOD AND FLUORESCENCE-LABELED OLIGONUCLEOTIDE USED IN SAME
#133METHOD FOR DETECTING GENETIC MUTATION
#134LONG NUCLEIC ACID SEQUENCES CONTAINING VARIABLE REGIONS
#135Nuclease-mediated DNA assembly
#136Methods and materials for assembling nucleic acid constructs
#137METHODS AND COMPOSITIONS FOR CLONING INTO LARGE VECTORS
#138Methods for Nucleic Acid Assembly
#139Using RNA-guided FokI nucleases (RFNs) to increase specificity for RNA-guided genome editing
#140Random nucleotide mutation for nucleotide template counting and assembly
#141Method for producing dicarboxylic acid
#142Global gene regulators (GGR) as vaccine candidates against
#143METHODS OF SYNTHESIZING POLYNUCLEOTIDES
#144High efficiency, small volume nucleic acid synthesis
#145One-pot multiplex gene synthesis
#146In vitro method for fast scarless DNA assembly using thermostable exonucleases and ligase
#147Libraries of Nucleic Acids and Methods for Making the Same
#148COMPOSITIONS AND METHODS FOR SYNTHETIC GENE ASSEMBLY
#149Using truncated guide RNAs (tru-gRNAs) to increase specificity for RNA-guided genome editing
#150Fusion polymerase and method for using the same
#151Rapid assembly of multiple arbitrary length DNA fragments
#152Comprehensive in vitro reporting of cleavage events by sequencing (Circle-seq)
#153Methods for sequencing nucleic acids
#154Methods for efficient, expansive, user-defined DNA mutagenesis
#155Method for synthesizing gene using high-depth oligonucleotide tiling
#156Compositions and methods for the construction of a random allelic series
#157Cas9 crystals and methods of use thereof
#158Compositions and methods for synthetic gene assembly
#159Methods and compositions for rapid seamless DNA assembly
#160Method of preparing nucleic acid molecules
#161Antibody like protein
#162Methods for cloning and manipulating genomes
#163Fusion polymerase and method for using the same
#164Compositions for making random codon-mutant libraries and uses thereof
#165Assembly of high fidelity polynucleotides
#166Compositions, methods and apparatus for oligonucleotides synthesis
#167Scalable method for isolation and sequence-verification of oligonucleotides from complex libraries
#168Nuclease-mediated DNA assembly
#169ANTIBODY LIKE PROTEIN
#170Synthon formation
#171RNA-guided targeting of genetic and epigenomic regulatory proteins to specific genomic loci
#172Nuclease-mediated DNA assembly
#173Compositions and methods for multiplex nucleic acids synthesis
#174Compositions and methods for synthesis of high fidelity oligonucleotides
#175Compositions and methods relating to complex nucleic acid nanostructures
#176PROGRAMMABLE ITERATED ELONGATION: A METHOD FOR MANUFACTURING SYNTHETIC GENES AND COMBINATORIAL DNA AND PROTEIN LIBRARIES
#177Compositions and Methods for High Fidelity Assembly of Nucleic Acids
#178Methods for generating pools of variants of a DNA template
#179Methods for Nucleic Acid Assembly and High Throughput Sequencing
#180Methods for efficient, expansive, user-defined DNA mutagenesis
#181LONG NUCLEIC ACID SEQUENCES CONTAINING VARIABLE REGIONS
#182Protein assembler
#183Assembly of nucleic acid sequences in emulsions
#184DNA assembly using an RNA-programmable nickase
#185Method of preparing nucleic acid molecules
#186Method for large-scale synthesis of long-chain nucleic acid molecule
#187Rapid assembly of multiple arbitrary length DNA fragments
#188Orthogonal Amplification and Assembly of Nucleic Acid Sequences
#189Method for the assembly of a polynucleic acid sequence
#190Methods for efficient, expansive user-defined DNA mutagenesis
#191RNA-mediated gene assembly from DNA oligonucleotides
#192Assembly of high fidelity polynucleotides
#193Compositions and Methods For High Fidelity Assembly of Nucleic Acids
#194PKD ligands and polynucleotides encoding PKD ligands
#195MODULAR METHOD FOR RAPID ASSEMBLY OF DNA
#196METHODS AND COMPOSITIONS FOR POLYPEPTIDE ENGINEERING
#197Gene synthesis by convergent assembly of oligonucleotide subsets
#198Method for In Vitro Molecular Evolution of Protein Function
#199INTEGRATED MICROFLUIDIC DEVICE FOR GENE SYNTHESIS
#200Sequential addition of short DNA oligos in DNA-polymerase-based synthesis reactions
#201Deducing exon connectivity by RNA-templated DNA ligation/sequencing
#202METHODS FOR CREATING ANTIBODY LIBRARIES
#203METHODS AND COMPOSITIONS FOR POLYPEPTIDE ENGINEERING
#204Methods for cloning and manipulating genomes
#205Methods for cloning and manipulating genomes
#206Method for in vitro recombination
#207Programmable iterated elongation: a method for manufacturing synthetic genes and combinatorial DNA and protein libraries
#208Self-replicating materials
#209LADDER ASSEMBLY AND SYSTEM FOR GENERATING DIVERSITY
#210FOCUSED LIBRARY GENERATION
#211Polyhedral Nanostructures Formed from Nucleic Acids
#212PKD ligands and polynucleotides encoding PKD ligands
#213Methods and compositions for polypeptide engineering
#214METHODS AND CELLS FOR CREATING FUNCTIONAL DIVERSITY AND USES THEREOF
#215Methods of making modular fusion protein expression products
#216METHOD AND SYSTEM FOR ASSEMBLY OF MACROMOLECULES AND NANOSTRUCTURES
#217Versatile nucleic acid hairpin motif for programming biomolecular self-assembly pathways
#218METHOD FOR IN VITRO MOLECULAR EVOLUTION OF PROTEIN FUNCTION
#219Integrated systems and methods for diversity generation and screening
#220Multidimensional organization of heteromolecules by robust DNA motifs
#221Method of generating long nucleic acid molecules of defined sequence
#222Method for the synthesis of DNA sequences
#223Method for in vitro recombination
#224Methods and compositions for polypeptide engineering
#225Heirarchical assembly methods for genome engineering
#226Methods and compositions for polypeptide engineering
#227Ladder assembly and system for generating diversity
#228Methods and compositions for polypeptide engineering
#229Compositions and methods for protein design
#230Non-random method of gene shuffling
#231Methods and compositions for polypeptide engineering
#232Polygonal nanostructures of polynucleic acid multi-crossover molecules and assembly of lattices based on double crossover cohesion
#233Oligonucleotide mediated nucleic acid recombination
#234Polynucleotide nanomechanical device that acts as an artificial ribosome and translates DNA signals into polymer assembly instructions
#235Sequential addition of short DNA oligos in DNA-polymerase-based synthesis reactions
#236Method for in vitro molecular evolution of protein function
#237Synthetic genes
#238Identifying oligonucleotides for in vitro recombination
#239Process for preparing variant polynucleotides
#240Methods for synthesis of defined polynucleotides
#241Methods and compositions for polypeptide engineering
#242System and method for creating crystals of human acetylcholinesterase with open active sites