ClassID:

109047

C12N15/111 - page 14 - CPC Classification

Classification description:

Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor; Recombinant DNA-technology; DNA or RNA fragments; Modified forms thereof General methods applicable to biologically active non-coding nucleic acids

Recent Application in this class:
#3901
20100267941
2010-10-21

iRNA agents with biocleavable tethers

#3902
20100267813
2010-10-21

Method for inhibiting the activity of mir-155

#3903
20100267810
2010-10-21

METHODS AND COMPOSITIONS FOR TREATING NEUROLOGICAL DISEASE

#3904
20100267809
2010-10-21

Double stranded nucleic acid targeting low copy promoter-specific RNA

#3905
20100267806
2010-10-21

LIPID FORMULATED COMPOSITIONS AND METHODS FOR INHIBITING EXPRESSION OF Eg5 AND VEGF GENES

#3906
20100267802
2010-10-21

DELIVERY METHOD

#3907
20100267587
2010-10-21

siRNA targeting cyclin dependent kinase 11 (CDK11)

#3908
20100267586
2010-10-21

siRNA targeting KRAS

#3909
20100267149
2010-10-21

Methods of determining potency of chemically-synthesized oligonucleotides

#3910
20100267146
2010-10-21

Method for expression of small antiviral RNA molecules with reduced cytotoxicity within a cell

#3911
20100266680
2010-10-21

Treatment of cancer using TLR3 agonists

#3912
20100263066
2010-10-14

INERT DNA SEQUENCES FOR EFFICIENT VIRAL PACKAGING AND METHODS OF USE

#3913
20100261231
2010-10-14

Dinucleotide MRNA cap analogs

#3914
20100261175
2010-10-14

USE OF SHORT OLIGONUCLEOTIDES FOR REAGENT REDUNDANCY EXPERIMENTS IN RNA FUNCTIONAL ANALYSIS

#3915
20100260855
2010-10-14

Delivery of AS-oligonucleotide microspheres to induce dendritic cell tolerance for the treatment of autoimmune type 1 diabetes

#3916
20100260850
2010-10-14

Controlled Release Devices and Methods for Delivery of Nucleic Acids

#3917
20100260780
2010-10-14

Uniform field magnetization and targeting of therapeutic formulations

#3918
20100257634
2010-10-07

BIOASSAY FOR GENE SILENCING CONSTRUCTS

#3919
20100256222
2010-10-07

Micro-RNA scaffolds, non-naturally occurring micro-RNAs, and methods for optimizing non-naturally occurring micro-RNAs

#3920
20100255545
2010-10-07

Integrated—ligand-responsive microRNAs

#3921
20100255112
2010-10-07

Efficient Nuclear Delivery of Antisense Oligonucleotides or siRNA In Vitro and In Vivo by Nano-Transforming Polymersomes

#3922
20100255023
2010-10-07

Dendritic cell vaccine compositions and uses of same

#3923
20100251392
2010-09-30

METHODS FOR ASSESSING THE DELIVERY OF EXOGENOUS AGENTS

#3924
20100249215
2010-09-30

Oligomeric compounds and compositions for use in modulation of pri-miRNAs

#3925
20100249214
2010-09-30

MULTIPLEX DICER SUBSTRATE RNA INTERFERENCE MOLECULES HAVING JOINING SEQUENCES

#3926
20100248990
2010-09-30

siRNA targeting ribonucleotide reductase M2 polypeptide (RRM2 or RNR-R2)

#3927
20100247662
2010-09-30

Biologic Modulations with Nanoparticles

#3928
20100240881
2010-09-23

Therapeutic compositions

#3929
20100240734
2010-09-23

METHODS AND COMPOSITIONS FOR THE SPECIFIC INHIBITION OF GENE EXPRESSION BY DOUBLE-STRANDED RNA

#3930
20100240730
2010-09-23

RNA Interference Mediated Inhibition of Gene Expression Using Chemically Modified Short Interfering Nucleic Acid (siNA)

#3931
20100240554
2010-09-23

SiRNA targeting glucagon receptor (GCGR)

#3932
20100239546
2010-09-23

BACTERIAL MEDIATED TNF ALPHA GENE SILENCING

#3933
20100234583
2010-09-16

siRNA target hypoxia-inducible factor 1

#3934
20100234582
2010-09-16

siRNA targeting gremlin

#3935
20100234448
2010-09-16

Vivo production of small interfering RNAs that mediate gene silencing

#3936
20100234444
2010-09-16

Hindered ester-based biodegradable linkers for oligonucleotide delivery

#3937
20100234282
2010-09-16

System for delivering nucleic acids for suppressing target gene expression by utilizing endogenous chylomicron

#3938
20100234281
2010-09-16

Antibacterial antisense oligonucleotide and method

#3939
20100234280
2010-09-16

ANTISENSE ANTIBACTERIAL METHOD AND COMPOUND

#3940
20100233810
2010-09-16

In vivo production of small interfering RNAS that mediate gene silencing

#3941
20100233678
2010-09-16

TUNABLE AFFINITY LIGANDS FOR THE SEPARATION AND DETECTION OF TARGET SUBSTANCES

#3942
20100228018
2010-09-09

RNA INTERFERENCE MEDIATED INHIBITION OF PROLIFERATING CELL NUCLEAR ANTIGEN (PCNA) GENE EXPRESSION USING SHORT INTERFERING NUCLEIC ACID (siNA)

#3943
20100227909
2010-09-09

Compositions comprising MIR34 therapeutic agents for treating cancer

#3944
20100227318
2010-09-09

Method for controlling the amount of gene product, and agent for controlling the amount of gene product

#3945
20100226901
2010-09-09

Genetic control of mammalian cells with synthetic RNA regulatory systems

#3946
20100226899
2010-09-09

Categorization of Microbial Communities

#3947
20100222414
2010-09-02

siRNA sequence-independent modification formats for reducing off-target phenotypic effects in RNAi, and stabilized forms thereof

#3948
20100221789
2010-09-02

High potency siRNAS for reducing the expression of target genes

#3949
20100221266
2010-09-02

Methods to regulate miRNA processing by targeting Lin-28

#3950
20100216982
2010-08-26

Polycyclic sugar surrogate-containing oligomeric compounds and compositions for use in gene modulation

#3951
20100216868
2010-08-26

AGENTS, COMPOSITIONS AND METHODS FOR TREATING PATHOLOGIES IN WHICH REGULATING AN ACHE-ASSOCIATED BIOLOGICAL PATHWAY IS BENEFICIAL

#3952
20100216238
2010-08-26

Compositions and methods for modulation of SMN2 splicing

#3953
20100215729
2010-08-26

Oligonucleotide analogues incorporating 5-aza-cytosine therein

#3954
20100215588
2010-08-26

THERAPEUTIC DELIVERY OF INHIBITORY NUCLEIC ACID MOLECULES TO THE RESPIRATORY SYSTEM

#3955
20100210712
2010-08-19

Short oligomer antagonist compounds for the modulation of target mRNA

#3956
20100209491
2010-08-19

METHOD FOR ENHANCING SERUM STABILITY AND LOWERING IMMUNE RESPONSE OF SIRNA DOWN-REGULATING GENE EXPRESSION OF HBV OR HCV

#3957
20100209487
2010-08-19

Nicked or gapped nucleic acid molecules and uses thereof

#3958
20100209440
2010-08-19

Targeted delivery of siRNA

#3959
20100204297
2010-08-12

INFLUENZA THERAPEUTIC

#3960
20100203036
2010-08-12

TARGETS FOR TUMOR GROWTH INHIBITION

#3961
20100197899
2010-08-05

Single-stranded and double-stranded oligonucleotides comprising a 2-arylpropyl moiety

#3962
20100197762
2010-08-05

Antisense compounds

#3963
20100197023
2010-08-05

MODIFIED POLYNUCLEOTIDES FOR USE IN RNA INTERFERENCE

#3964
20100197012
2010-08-05

Application of RNA Interference Targeting dhfr Gene, to Cell for Producing Secretory Protein

#3965
20100196393
2010-08-05

Modulation of blood brain barrier protein expression

#3966
20100196335
2010-08-05

Methods and Compositions for Regulated Expressions of Nucleic Acid at Post-Transcriptional Level

#3967
20100196277
2010-08-05

NANOPARTICLE COMPOSITIONS FOR CONTROLLED DELIVERY OF NUCLEIC ACIDS

#3968
20100190971
2010-07-29

SiRNA targeting diacylglycerol O-acyltransferase homolog 2 (DGAT2)

#3969
20100190837
2010-07-29

5'-Substituted-2-F' Modified Nucleosides and Oligomeric Compounds Prepared Therefrom

#3970
20100190691
2010-07-29

DELIVERY OF NUCLEIC ACIDS USING CELL-PENETRATING PEPTIDES

#3971
20100190258
2010-07-29

Method of producing recombinant biological products

#3972
20100190243
2010-07-29

siRNA-MEDIATED GENE SILENCING WITH VIRAL VECTORS

#3973
20100189725
2010-07-29

P53 modulator and cancer target

#3974
20100189691
2010-07-29

E. Coli Mediated Gene Silencing of Beta-Catenin

#3975
20100186103
2010-07-22

Isolation of novel AAV'S and uses thereof

#3976
20100186097
2010-07-22

CELL-BASED RNA INTERFERENCE AND RELATED METHODS AND COMPOSITIONS

#3977
20100184841
2010-07-22

EXTENDED DICER SUBSTRATE AGENTS AND METHODS FOR THE SPECIFIC INHIBITION OF GENE EXPRESSION

#3978
20100184840
2010-07-22

PRIMARY MICRO RNA EXPRESSION CASSETTE

#3979
20100184835
2010-07-22

Devices, systems and methods for improving memory and/or cognitive function through brain delivery of siRNA

#3980
20100184828
2010-07-22

Methods and compositions for enhancing the efficacy and specificity of RNA silencing

#3981
20100184827
2010-07-22

Methods and compositions for enhancing the efficacy and specificity of RNA silencing

#3982
20100184826
2010-07-22

Methods and compositions for enhancing the efficacy and specificity of RNA silencing

#3983
20100184822
2010-07-22

Method of modulating the activity of a nucleic acid molecule

#3984
20100184810
2010-07-22

METHODS AND COMPOSITIONS RELATED TO RIBOSWITCHES THAT CONTROL ALTERNATIVE SPLICING

#3985
20100184209
2010-07-22

COMPOSITIONS AND METHODS FOR INHIBITING GENE SILENCING BY RNA INTERFERENCE

#3986
20100184207
2010-07-22

Methods for producing interfering RNA molecules in mammalian cells and therapeutic uses for such molecules

#3987
20100183634
2010-07-22

Multifunctional nucleic acid nano-structures

#3988
20100179309
2010-07-15

Modified iRNA agents

#3989
20100178653
2010-07-15

GENE EXPRESSION SIGNATURE FOR CLASSIFICATION OF CANCERS

#3990
20100178325
2010-07-15

AMPHIPHILIC NUCLEOTIDE COCHLEATE COMPOSITIONS AND METHODS OF USING THE SAME

#3991
20100175141
2010-07-08

Tunable genetic switch for regulating gene expression

#3992
20100173974
2010-07-08

Extended dicer substrate agents and methods for the specific inhibition of gene expression

#3993
20100173973
2010-07-08

EXTENDED DICER SUBSTRATE AGENTS AND METHODS FOR THE SPECIFIC INHIBITION OF GENE EXPRESSION

#3994
20100172976
2010-07-08

METHODS AND COMPOSITIONS FOR INHIBITING THE FUNCTION OF POLYNUCLEOTIDE SEQUENCES

#3995
20100172882
2010-07-08

COMPOSITIONS AND METHODS FOR TARGETED INACTIVATION OF HIV CELL SURFACE RECEPTORS

#3996
20100170000
2010-07-01

Rna constructs

#3997
20100168208
2010-07-01

RNA interference mediated treatment of alzheimer's disease using short interfering nucleic acid (siNA)

#3998
20100166661
2010-07-01

siRNA compositions and methods for potently inhibiting viral infection

#3999
20100160208
2010-06-24

Pharmaceutical composition

#4000
20100159591
2010-06-24

Methods and compositions concerning siRNA's as mediators of RNA interference

#4001
20100158869
2010-06-24

Method for treatment of Huntington's disease through intracranial delivery of sirna

#4002
20100154072
2010-06-17

siRNA Kinase and Methods of Use

#4003
20100152282
2010-06-17

Use of double stranded RNA hairpin duplexes in gene silencing

#4004
20100152064
2010-06-17

siRNA targeting BCL2L1

#4005
20100145039
2010-06-10

siRNA targeting nucleoporin 62kDa (Nup62)

#4006
20100144845
2010-06-10

OLIGONUCLEOTIDE SYSTEMS FOR TARGETED INTRACELLULAR DELIVERY

#4007
20100144842
2010-06-10

RNA interference mediated inhibition of NOGO and NOGO receptor gene expression using short interfering nucleic acid (siNA)

#4008
20100144831
2010-06-10

BLOCKING OF GENE EXPRESSION IN EUKARYOTIC CELLS

#4009
20100144552
2010-06-10

siRNA targeting serine/threonine kinase 12 (STK12 or aurora B kinase)

#4010
20100144038
2010-06-10

Composition And Method For Increasing Efficiency Of Introduction Of Target Substance Into Cell

#4011
20100143386
2010-06-10

FGFR4 Promotes Cancer Cell Resistance in Response to Chemotherapeutic Drugs

#4012
20100137411
2010-06-03

RAS-MEDIATED EPIGENETIC SILENCING EFFECTORS AND USES THEREOF

#4013
20100137407
2010-06-03

SINGLE-CHAIN CIRCULAR RNA AND METHOD OF PRODUCING THE SAME

#4014
20100136695
2010-06-03

DOUBLE-STRANDED OLIGONUCLEOTIDES

#4015
20100136682
2010-06-03

Polyvalent RNA-nanoparticle compositions

#4016
20100136614
2010-06-03

Dendrimer-like modular delivery vector

#4017
20100136547
2010-06-03

Pure miRNA Sample Preparation Method

#4018
20100130591
2010-05-27

Multiple exon skipping compositions for DMD

#4019
20100130588
2010-05-27

Lipid formulations for nucleic acid delivery

#4020
20100129460
2010-05-27

COMPOUNDS AND METHODS FOR PEPTIDE RIBONUCLEIC ACID CONDENSATE PARTICLES FOR RNA THERAPEUTICS

#4021
20100129429
2010-05-27

Inhibition of autophagy genes in cancer chemotherapy

#4022
20100125919
2010-05-20

METHODS AND COMPOSITIONS FOR MODULATING THE MIRNA PATHWAY

#4023
20100125100
2010-05-20

Method of using gold nanorods-siRNA complexes

#4024
20100121043
2010-05-13

Environment-responding siRNA carrier using disulfide-cross-linked polymeric micelle

#4025
20100120893
2010-05-13

Compositions and methods for inhibiting expression of transthyretin

#4026
20100113761
2010-05-06

siRNA targeting beta secretase (BACE)

#4027
20100113760
2010-05-06

SiRNA targeting myeloid differentiation primary response gene (88) (MYD88)

#4028
20100113332
2010-05-06

METHOD OF TREATING AN INFLAMMATORY DISEASE BY DOUBLE STRANDED RIBONUCLEIC ACID

#4029
20100113307
2010-05-06

siRNA targeting vascular endothelial growth factor (VEGF)

#4030
20100113306
2010-05-06

siRNA targeting connective tissue growth factor (CTGF)

#4031
20100113284
2010-05-06

SMALL INTERFERING RNA (SIRNA) TARGET SITE BLOCKING OLIGOS AND USES THEREOF

#4032
20100112686
2010-05-06

Short hairpin RNAs for inhibition of gene expression

#4033
20100112042
2010-05-06

Processes and Compositions for Liposomal and Efficient Delivery of Gene Silencing Therapeutics

#4034
20100105565
2010-04-29

Evolved orthogonal ribosomes

#4035
20100105134
2010-04-29

NUCLEIC ACID COMPOUNDS FOR INHIBITING GENE EXPRESSION AND USES THEREOF

#4036
20100105120
2010-04-29

Photocleavable sense-antisense complex

#4037
20100104584
2010-04-29

GENES INVOLVED IN MITOCHONDRIAL BIOGENESIS

#4038
20100104533
2010-04-29

EARLY INTERVENTION OF VIRAL INFECTION WITH IMMUNE ACTIVATORS

#4039
20100099578
2010-04-22

SiRNA targeting fructose-1, 6-bisphosphatase 1 (FBP1)

#4040
20100099191
2010-04-22

RNA interference tags

#4041
20100093987
2010-04-15

Inhibitor Nucleic Acids

#4042
20100093090
2010-04-15

METHOD AND KIT FOR EFFICIENT REPROGRAMMING OF SOMATIC CELLS

#4043
20100093085
2010-04-15

Tripartite oligonucleotide complexes and methods for gene silencing by RNA interference

#4044
20100092524
2010-04-15

Modification of exosomal components for use as a vaccine

#4045
20100092438
2010-04-15

Bacteria mediated gene silencing

#4046
20100088775
2010-04-08

METHODS OF MODULATING EPITHELIAL-MESENCHYMAL TRANSITION AND MESENCHYMAL-EPITHELIAL TRANSITION IN CELLS AND AGENTS USEFUL FOR THE SAME

#4047
20100087514
2010-04-08

METHOD AND MEANS FOR TREATMENT OF OSTEOARTHRITIS

#4048
20100087509
2010-04-08

Methods, agents, and compound screening assays for inducing differentiation of undifferentiated mammalian cells into osteoblasts

#4049
20100087335
2010-04-08

siRNA targeting spleen tyrosine kinase

#4050
20100087334
2010-04-08

siRNA targeting superoxide dismutase 1 (SOD1)

#4051
20100081704
2010-04-01

Isoform of bruton's tyrosine kinase (BTK) protein

#4052
20100081201
2010-04-01

Olig1 mini-promoters

#4053
20100077495
2010-03-25

COMPOSITIONS AND METHODS FOR THE EXPRESSION OF NUCLEIC ACIDS

#4054
20100076054
2010-03-25

Sensizitation of cancer cells to therapy using siNA targeting genes from the 1p and 19q chromosomal regions

#4055
20100075869
2010-03-25

siRNA targeting TATA box binding protein (TBP)-associated factor (TAF1)

#4056
20100075423
2010-03-25

METHODS AND COMPOSITIONS RELATING TO POLYPEPTIDES WITH RNASE III DOMAINS THAT MEDIATE RNA INTERFERENCE

#4057
20100069622
2010-03-18

siRNA targeting amyloid beta (A4) precursor protein (APP)

#4058
20100069471
2010-03-18

Chemically modified oligonucleotides

#4059
20100069465
2010-03-18

METHODS AND COMPOSITIONS FOR THE SPECIFIC INHIBITION OF GENE EXPRESSION BY DOUBLE-STRANDED RNA

#4060
20100069261
2010-03-18

siRNA targeting proto-oncogene MET

#4061
20100068814
2010-03-18

Multi-microRNA methods and compositions

#4062
20100063134
2010-03-11

Treatment of neurodegenerative disease through intracranial delivery of SIRNA

#4063
20100063132
2010-03-11

SMALL INTERFERING RNA AND PHARMACEUTICAL COMPOSITION FOR TREATMENT OF HEPATITIS B COMPRISING THE SAME

#4064
20100063131
2010-03-11

Prompt nucleic acid delivery carrier composition

#4065
20100062951
2010-03-11

siRNA targeting TIE-2

#4066
20100056768
2010-03-04

Hydroxymethyl substituted RNA oligonucleotides and RNA complexes

#4067
20100056475
2010-03-04

CYCLODEXTRIN CONJUGATES

#4068
20100056395
2010-03-04

siRNA targeting coatomer protein complex, subunit beta 2 (CPOB2)

#4069
20100048682
2010-02-25

INHIBITING DNA POLYMERASE BETA TO ENHANCE EFFICACY OF ANTICANCER AGENTS

#4070
20100048425
2010-02-25

siRNA targeting tumor protein 53 (p53)

#4071
20100047804
2010-02-25

Methods for distinguishing between lung squamous carcinoma and other non small cell lung cancers

#4072
20100041738
2010-02-18

HYBRIDIZATION-STABILIZING CONSTRUCT

#4073
20100040576
2010-02-18

Modified Oligonucleotides For The Treatment Of Hepatitis C Infection

#4074
20100035974
2010-02-11

COMPOSITIONS COMPRISING A SIRNA AND LIPIDIC 4,5-DISUBSTITUTED 2-DEOXYSTREPTAMINE RING AMINOGLYCOSIDE DERIVATIVES AND USES THEREOF

#4075
20100035969
2010-02-11

RNAi inhibition of CTGF for treatment of ocular disorders

#4076
20100035966
2010-02-11

Methods and compositions for regulating cell cycle progression

#4077
20100029747
2010-02-04

METHODS AND COMPOSITIONS FOR INHIBITING THE FUNCTION OF POLYNUCLEOTIDE SEQUENCES

#4078
20100029510
2010-02-04

siRNA targeting survivin

#4079
20100029501
2010-02-04

METHOD OF IDENTIFYING MICRO-RNA TARGETS

#4080
20100029003
2010-02-04

System and methods for identifying miRNA targets and for altering miRNA and target expression

#4081
20100028998
2010-02-04

RNAi expression constructs

#4082
20100028996
2010-02-04

Retroviral vectors for delivery of interfering RNA

#4083
20100028863
2010-02-04

High throughput assay for cancer cell growth inhibition

#4084
20100028848
2010-02-04

Compositions and Methods of Using siRNA to Knockdown Gene Expression and to Improve Solid Organ and Cell Transplantation

#4085
20100022763
2010-01-28

siRNA targeting kinase insert domain receptor (KDR)

#4086
20100022618
2010-01-28

Long interfering nucleic acid duplexes targeting multiple RNA targets

#4087
20100022413
2010-01-28

SiRNA targeting ras-related nuclear protein RAN

#4088
20100021914
2010-01-28

OLIGONUCLEOTIDES FOR MODULATING TARGET RNA ACTIVITY

#4089
20100016574
2010-01-21

2′-hydroxyl group-modified ribonucleoside derivatives

#4090
20100016573
2010-01-21

SiRNA targeting cyclin-dependent kinase inhibitor 1B (p27, Kip1) (CDKN1B)

#4091
20100016409
2010-01-21

Rna Nanoparticles and Nanotubes

#4092
20100016176
2010-01-21

siRNA targeting histamine receptor H1

#4093
20100015232
2010-01-21

NANOPARTICLES FOR NUCLEIC ACID DELIVERY

#4094
20100010207
2010-01-14

RNA INTERFERENCE MEDIATING SMALL RNA MOLECULES

#4095
20100010206
2010-01-14

siRNA targeting hypoxia-inducible factor 1

#4096
20100010072
2010-01-14

MicroRNA biomarkers for human breast and lung cancer

#4097
20100010067
2010-01-14

Arginine-conjugated bioreducible poly(disulfide amine) polymers for gene delivery system

#4098
20100009856
2010-01-14

Randomized dna libraries and double-stranded rna libraries, use and method of production thereof

#4099
20100009451
2010-01-14

COMPOSITIONS AND METHODS FOR SPECIFICALLY SILENCING A TARGET NUCLEIC ACID

#4100
20100009446
2010-01-14

Biologically active molecules, particularly based on PNA and siRNA, method for the cell-specific activation thereof, and application kit to be administered

#4101
20100008937
2010-01-14

TARGETED DELIVERY TO LEUKOCYTES USING NON-PROTEIN CARRIERS

#4102
20100004436
2010-01-07

METHODS AND COMPOSITIONS FOR THE SPECIFIC INHIBITION OF GENE EXPRESSION BY DOUBLE-STRANDED RNA

#4103
20100004435
2010-01-07

METHODS AND COMPOSITIONS FOR THE SPECIFIC INHIBITION OF GENE EXPRESSION BY DOUBLE-STRANDED RNA

#4104
20100004434
2010-01-07

METHODS AND COMPOSITIONS FOR THE SPECIFIC INHIBITION OF GENE EXPRESSION BY DOUBLE-STRANDED RNA

#4105
20100004318
2010-01-07

METHODS AND COMPOSITIONS FOR THE SPECIFIC INHIBITION OF GENE EXPRESSION BY DOUBLE-STRANDED RNA

#4106
20100004317
2010-01-07

METHODS AND COMPOSITIONS FOR THE SPECIFIC INHIBITION OF GENE EXPRESSION BY DOUBLE-STRANDED RNA

#4107
20100004142
2010-01-07

siRNA targeting myeloid cell Leukemia sequence 1

#4108
20100004141
2010-01-07

siRNA targeting polo-like Kinase-1 (PLK-1)

#4109
20100003758
2010-01-07

METHODS AND COMPOSITIONS FOR THE SPECIFIC INHIBITION OF GENE EXPRESSION BY DOUBLE-STRANDED RNA

#4110
20100003753
2010-01-07

Multivalent rna nanoparticles for delivery of active agents to a cell

#4111
20090326208
2009-12-31

Methods and compositions for generating recombinant nucleic acid molecules

#4112
20090326051
2009-12-31

Modulation of gene expression through endogenous small RNA targeting of gene promoters

#4113
20090326046
2009-12-31

METHODS AND COMPOSITIONS FOR THE SPECIFIC INHIBITION OF GENE EXPRESSION BY DOUBLE-STRANDED RNA

#4114
20090325818
2009-12-31

siRNA targeting interleukin-1 receptor-associated kinase 4 (IRAK4)

#4115
20090325291
2009-12-31

METHOD OF PREPARING siRNAs FOR SELECTIVE INHIBITION OF TARGET mRNA ISOTYPES

#4116
20090325286
2009-12-31

METHODS AND COMPOSITIONS FOR THE SPECIFIC INHIBITION OF GENE EXPRESSION BY DOUBLE-STRANDED RNA

#4117
20090325285
2009-12-31

METHODS AND COMPOSITIONS FOR THE SPECIFIC INHIBITION OF GENE EXPRESSION BY DOUBLE-STRANDED RNA

#4118
20090325181
2009-12-31

METHODS AND COMPOSITIONS FOR THE SPECIFIC INHIBITION OF GENE EXPRESSION BY DOUBLE-STRANDED RNA

#4119
20090325150
2009-12-31

KLF6 ALTERNATIVE SPLICE FORMS AND A GERMLINE KLF6 DNA POLYMORPHISM ASSOCIATED WITH INCREASED CANCER RISK

#4120
20090318676
2009-12-24

Oligonucleotides comprising a non-phosphate backbone linkage

#4121
20090317907
2009-12-24

Oligomeric compounds and compositions for use in modulation of small non-coding RNAs

#4122
20090317906
2009-12-24

GENE SILENCING USING SENSE DNA AND ANTISENSE RNA HYBRID CONSTRUCTS COUPLED TO PEPTIDES FACILITATING THE UPTAKE INTO CELLS

#4123
20090317802
2009-12-24

Compositions and Methods to Monitor RNA Delivery to Cells

#4124
20090312532
2009-12-17

Modulation of exon recognition in pre-mrna by interfering with the binding of sr proteins and by interfering with secodary rna structure

#4125
20090312402
2009-12-17

ENCAPSULATED NANOPARTICLES FOR DRUG DELIVERY

#4126
20090312394
2009-12-17

Protection against and treatment of age related macular degeneration

#4127
20090312393
2009-12-17

Cancer therapy using Bcl-X-specific siNA

#4128
20090311244
2009-12-17

Screening method

#4129
20090311233
2009-12-17

Materials and methods directed to asparagine synthetase and asparaginase therapies

#4130
20090307788
2009-12-10

RIBOZYME MEDIATED STABILIZATION OF POLYNUCLEOTIDES

#4131
20090306356
2009-12-10

siRNA targeting TNFα

#4132
20090306178
2009-12-10

CONJUGATED DOUBLE STRAND COMPOSITIONS FOR USE IN GENE MODULATION

#4133
20090306177
2009-12-10

Modulation of Immunostimulatory Properties of Short Interfering Ribonucleic Acid (Sirna) by Nucleotide Modification

#4134
20090306176
2009-12-10

Use of low doses of oligonucleotides antisense to TGF-β genes in the treatment of brain tumors

#4135
20090304717
2009-12-10

Immuno-RNA-constructs

#4136
20090304630
2009-12-10

Treating severe and acute viral infections

#4137
20090304592
2009-12-10

Treatment of metastatic tumors

#4138
20090298913
2009-12-03

SMALL INTERFERING OLIGONUCLEOTIDES COMPRISING ARABINOSE MODIFIED NUCLEOTIDES

#4139
20090298910
2009-12-03

Regulation of epigenetic control of gene expression

#4140
20090298909
2009-12-03

Multiple RNA polymerase III promoter expression constructs

#4141
20090298176
2009-12-03

siRNA targeting KRAS

#4142
20090298174
2009-12-03

Oligomeric compounds and compositions for use in modulation of small non-coding RNAs

#4143
20090297487
2009-12-03

METHOD FOR INTRODUCING SIRNA INTO CELLS BY PHOTOCHEMICAL INTERNALISATION

#4144
20090292003
2009-11-26

Cell penetrating peptides for intracellular delivery of molecules

#4145
20090291907
2009-11-26

Oligomeric compounds and compositions for use in modulation of small non-coding RNAs

#4146
20090291906
2009-11-26

Oligomeric compounds and compositions for use in modulation of small non-coding RNAs

#4147
20090291497
2009-11-26

siRNA targeting transducin (beta)-like 3 (TBL3)

#4148
20090286973
2009-11-19

Ligand-conjugated monomers

#4149
20090286969
2009-11-19

Oligomeric Compounds And Compositions For Use In Modulation Of Small Non-Coding RNAs

#4150
20090286851
2009-11-19

Compositions and methods for delivering RNAI using lipoproteins

#4151
20090286753
2009-11-19

NOVEL OLIGONUCLEOTIDE COMPOSITIONS AND PROBE SEQUENCES USEFUL FOR DETECTION AND ANALYSIS OF MICRORNAS AND THEIR TARGET MRNAS

#4152
20090286287
2009-11-19

METHODS AND COMPOSITIONS FOR USE IN PREPARRING siRNAs

#4153
20090285788
2009-11-19

Random RNAi libraries, methods of generating same, and screening methods utilizing same

#4154
20090281299
2009-11-12

Oligonucleotides comprising a non-phosphate backbone linkage

#4155
20090281297
2009-11-12

siRNA targeting v-myc myelocytomatosis viral oncogene homolog (MYC)

#4156
20090280567
2009-11-12

STABILIZED SIRNAS AS TRANSFECTION CONTROLS AND SILENCING REAGENTS

#4157
20090280167
2009-11-12

ENHANCEMENT OF DRUG THERAPY BY MIRNA

#4158
20090280166
2009-11-12

FERRITIN AS A THERAPEUTIC TARGET IN ABNORMAL CELLS

#4159
20090280058
2009-11-12

Delivery Of Double-Stranded RNA Into The Central Nervous System

#4160
20090275640
2009-11-05

siRNA targeting inner centromere protein antigens (INCENP)

#4161
20090275635
2009-11-05

Method of inhibiting human Trabid

#4162
20090270481
2009-10-29

Modified siRNA molecules and uses thereof

#4163
20090269755
2009-10-29

Means and method for inducing exon-skipping

#4164
20090264636
2009-10-22

Conjugates and compositions for cellular delivery

#4165
20090264510
2009-10-22

Double helical oligonucleotides interfering with mRNA used as effective anticancer agents

#4166
20090264508
2009-10-22

Focused libraries, functional profiling, laser SELEX, and DESELEX

#4167
20090264504
2009-10-22

RNA INTERFERENCE MEDIATED INHIBITION OF HUMAN IMMUNODEFICIENCY VIRUS (HIV) GENE EXPRESSION USING SHORT INTERFERING NUCLEIC ACID (siNA)

#4168
20090263803
2009-10-22

MIRNAS DIFFERENTIALLY EXPRESSED IN LYMPH NODES FROM CANCER PATIENTS

#4169
20090263364
2009-10-22

Method and constructs for delivering double stranded RNA to pest organisms

#4170
20090258931
2009-10-15

Chimeric oligomeric compounds comprising alternating regions of northern and southern conformational geometry

#4171
20090258930
2009-10-15

DOUBLE STRANDED RNA STRUCTURES AND CONSTRUCTS, AND METHODS FOR GENERATING AND USING THE SAME

#4172
20090258425
2009-10-15

GENE KNOCK-DOWN BY INTRACELLULAR EXPRESSION OF APTAMERS

#4173
20090258424
2009-10-15

Cellular Delivery of siRNA

#4174
20090258366
2009-10-15

pCryptoRNAi

#4175
20090253776
2009-10-08

siRNA targeting gremlin

#4176
20090247615
2009-10-01

Triggered RNAi

#4177
20090247613
2009-10-01

RNA INTERFERENCE MEDIATED INHIBITION OF B-CELL CLL/LYMPHOMA-2 (BCL2) GENE EXPRESSION USING SHORT INTERFERING NUCLEIC ACID (siNA)

#4178
20090247607
2009-10-01

dsRNA compositions and methods for treating HPV infection

#4179
20090247606
2009-10-01

RNA Interference Mediated Inhibition of Adenosine A1 Receptor (ADORA1) Gene Expression Using Short Interfering Nucleic Acid (siNA)

#4180
20090246833
2009-10-01

Small interfering RNAS as non-specific drugs

#4181
20090239816
2009-09-24

Multitargeting Interfering RNAs And Methods Of Their Use And Design

#4182
20090235373
2009-09-17

METHOD OF DELIVERY OF NUCLEIC ACIDS TO A DEVELOPING EMBRYO

#4183
20090234109
2009-09-17

Signal activated RNA interference

#4184
20090233981
2009-09-17

Compounds for Hydrolyzing Ribonucleic Acids (RNA's)

#4185
20090233365
2009-09-17

Arginine-conjugated bioreducible poly(disulfide amine) polymers for gene delivery systems

#4186
20090232730
2009-09-17

METHOD OF PRODUCING IMMUNOLIPOSOMES AND COMPOSITIONS THEREOF

#4187
20090227780
2009-09-10

siRNA targeting connexin 43

#4188
20090221808
2009-09-03

Process for the Preparation of Nucleic Acid Duplexes

#4189
20090221685
2009-09-03

Oligomeric compounds and compositions for the use in modulation of microRNAs

#4190
20090221679
2009-09-03

Novel HIV Targets

#4191
20090220584
2009-09-03

Amphoteric liposome formulation

#4192
20090220582
2009-09-03

Method of cancer treatment using siRNA silencing

#4193
20090220433
2009-09-03

Biotinylated compositions

#4194
20090216003
2009-08-27

Stable and selective formation of hoogsteen-type triplexes and duplexes using twisted intercalating nucleic acids (TINA) and process for the preparation of TINA

#4195
20090215864
2009-08-27

Oligoribonucleotide inhibitors of NRF2 and methods of use thereof for treatment of cancer

#4196
20090215860
2009-08-27

COMPOSITIONS AND METHODS FOR REGULATING GENE TRANSCRIPTION

#4197
20090215644
2009-08-27

RNA interference induction element and use thereof

#4198
20090215178
2009-08-27

Methods to enhance the stability and homogeneity of transgene expression in clonal cell lines

#4199
20090210955
2009-08-20

SHRNA AND SIRNA EXPRESSION IN A LIVING ORGANISM UNDER CONTROL OF A CODON-OPTIMIZED REPRESSOR GENE

#4200
20090209748
2009-08-20

Oligonucleotides with alternating segments of locked and non-locked nucleotides