Nucleic acid functionalized nanoparticles for therapeutic applications

MULTIPLE RNAi EXPRESSION CASSETTES FOR SIMULTANEOUS DELIVERY OF RNAi AGENTS RELATED TO HETEROZYGOTIC EXPRESSION PATTERNS

Duplex oligonucleotides with enhanced functionality in gene regulation

Anti-sense nucleic acid derived from organism

IDENTIFICATION OF MOLECULAR INTERACTIONS AND THERAPEUTIC USES THEREOF

Compositions of asymmetric interfering RNA and uses thereof

ATTENUATED SALMONELLA AS A DELIVERY SYSTEM FOR SIRNA-BASED TUMOR THERAPY

siRNA targeting cyclin-dependent kinase 4 (CDK4)

ANTISENSE COMPOUNDS HAVING ENHANCED ANTI-MICRORNA ACTIVITY

TRANS-SPLICING MEDIATED PHOTODYNAMIC THERAPY

Glycoconjugates of RNA interference agents

Intelligent nanomedicine integrating diagnosis and therapy

si-RNA-mediated gene silencing technology to inhibit tyrosinase and reduce pigmentation

2'-Modified Oligonucleotides

Modified short interfering RNA

COMPOSITIONS AND METHODS FOR PREPARING SHORT RNA MOLECULES AND OTHER NUCLEIC ACIDS

Functional nucleic acid ligands to fluorescent proteins

Methods and compositions for RNA interference

Interfering RNA duplex having blunt-ends and 3′-modifications

RNA interference mediated inhibition of hypoxia inducible factor 1 (HIF1) gene expression using short interfering nucleic acid (siNA)

Multitargeting interfering RNAs having two active strands and methods for their design and use

siRNA targeting connective tissue growth factor (CTGF)

Interfering RNA molecules

RNA sequence-specific mediators of RNA interference

IDENTIFICATION OF JAK/STAT PATHWAY MODULATING GENES BY GENOME WIDE RNAI SCREENING

RNA SILENCING COMPOSITIONS AND METHODS FOR THE TREATMENT OF HUNTINGTON'S DISEASE

DEVICE AND SUBSTANCE FOR THE IMMOBILIZATION OF MESENCHYMAL STEM CELLS (MSCs)

Methods of producing competitive aptamer fret reagents and assays

Small internally segmented interfering RNA

DOUBLE-STRANDED RNA STRUCTURES AND CONSTRUCTS, AND METHODS FOR GENERATING AND USING THE SAME

Methods and compositions involving miRNA and miRNA inhibitor molecules

Complex for transferring an anionic substance into a cell

Composition Suppressing The Expression of Target Gene in Eyeball and Medicament For Treating of Disease in Eyeball

CNS-tumor treatment method and composition

Cosmetic designs and products using intronic RNA

Method for determining immunostimulatory activity of RNA oligonucleotides

Modified gene-silencing RNA and uses thereof

siRNA targeting myeloid cell leukemia sequence 1

siRNA targeting tumor necrosis factor receptor superfamily member 1A

METHODS FOR DELIVERY OF NUCLEIC ACIDS

miR-200 REGULATED GENES AND PATHWAYS AS TARGETS FOR THERAPEUTIC INTERVENTION

miR-20 Regulated Genes and Pathways as Targets for Therapeutic Intervention

siRNA targeting hypoxia-inducible factor 1

Compositions and methods for modulation of LMNA expression

METHOD OF INHIBITING EXPRESSION OF TARGET MRNA USING SIRNA CONSISTING OF NUCLEOTIDE SEQUENCE COMPLEMENTARY TO SAID TARGET MRNA

RNA Interference Mediating Small RNA Molecules

SiRNA targeting KRAS

RNA interference mediated treatment of Alzheimer's disease using short interfering nucleic acid (siNA)

Application of RNA Interference Targeting DHFR Gene, to Cell for Protein Production

METHOD FOR TREATING CANCER USING INTERFERENCE RNA

Modular polynucleotides for ligand-controlled regulatory systems

MicroRNAs

Cell transfecting formulations of small interfering RNA related compositions and methods of making and use

Ladder copolymers

Methods and compositions for silencing genes without inducing toxicity

RNA interference mediated inhibition of cyclin D1 gene expression using short interfering nucleic acid (siNA)

RNA interference mediated inhibition of placental growth factor gene expression using short interfering nucleic acid (SINA)

RNA INTERFERENCE MEDIATED INHIBITION OF PROLIFERATION CELL NUCLEAR ANTIGEN (PCNA) GENE EXPRESSION USING SHORT INTERFERING NUCLEIC ACID (siNA)

RNA interference mediated inhibition of polycomb group protein EZH2 gene expression using short interfering nucleic acid (siNA)

Method for Predicting and Identifying Target mRnas Controlled By Functional Rnas and Method of Using the Same

MICRORNA TARGET SITE BLOCKING OLIGOS AND USES THEREOF

Genetic selection system for identification of MicroRNA target genes

Splicing-Mediated Regulation Of Gene Expression

Inducible SIRNA expression cassette and method of use

Tripartite RNAi constructs

LOW DENSITY LIPOPROTEIN RECEPTOR-MEDIATED siRNA DELIVERY

miR-15, miR-26, miR-31, miR-145, miR-147, miR-188, miR-215, miR-216, miR-331, mmu-miR-292-3P REGULATED GENES AND PATHWAYS AS TARGETS FOR THERAPEUTIC INTERVENTION

MULTICISTRONIC VECTORS AND METHODS FOR THEIR DESIGN

Reduction of off-target RNA interference toxicity

Synthetic Peptide Copolymers for Treatment and Prevention of Cardiovascular Disorders

Rna constructs

METHODS AND COMPOSITIONS FOR THE TREATMENT OF ERYTHROCYTE DISEASES

OLIGONUCLEIC ACID-BEARING COMPOSITE AND PHARMACEUTICAL COMPOSITION CONTAINING THE COMPOSITE

Compositions for Bacterial Mediated Gene Silencing and Methods of Using the Same

siRNA targeting nucleoporin 62kDa (Nup62)

Aptamer-based methods for identifying cellular biomarkers

Molecular targets and compounds, and methods to identify the same, useful in the treatment of bone and joint degenerative diseases

Stabilized Aptamers to PSMA and Their Use as Prostate Cancer Therapeutics

RNA interference mediated inhibition of Stearoyl-CoA desaturase (SCD) gene expression using short interfering nucelic acid (siNA)

RNA interference mediated inhibition of MYC and/or MYB gene expression using short interfering nucleic acid (siNA)

Construction of pool of interfering nucleic acids covering entire RNA target sequence and related compositions

Methods and compositions for controlling efficacy of RNA silencing

Higher-order cellular information processing devices

MRI contrast agents and high-throughput screening by MRI

Selex and photoSELEX

RNA interference mediated inhibition of NOGO and NOGO receptor gene expression using short interfering nucleic acid (siNA)

TRANSDUCIBLE DELIVERY OF NUCLEIC ACIDS BY REVERSIBLE PHOSPHOTRIESTER CHARGE NEUTRALIZATION PROTECTING GROUPS

Transducible delivery of siRNA by dsRNA binding domain fusions to PTD/CPPS

Modulating Gene Expression with agRNA and Gapmers Targeting Antisense Transcripts

Tetrahydropyran nucleic acid analogs

miRNA PROCESSING INHIBITOR EFFICACY ASSAYS AND SUBSTANCES

siRNA targeting transducin (beta)-like 3 (TBL3)

Oligonucleotide analogs having cationic intersubunit linkages

Primer-extension based method for the generation of siRNA/miRNA expression vectors

Sequence-specific inhibition of small RNA function

Uniform field magnetization and targeting of therapeutic formulations

siRNA targeting TATA box binding protein (TBP)-associated factor (TAF1)

Methods for producing microRNAs

Compositions and Methods for Regulating Gene Expression

Selection of nucleic acid-based sensor domains within nucleic acid switch platform

Polynucleotide for Target Gene

INHIBITING DNA POLYMERASE BETA TO ENHANCE EFFICACY OF ANTICANCER AGENTS

GENE SILENCING BY SYSTEMIC RNA INTERFERENCE

Metabolic profile directed aptamer medicinal chemistry

siRNA targeting inner centromere protein antigens (INCENP)

4'-THIOARABINONUCLEOTIDE-CONTAINING OLIGONUCLEOTIDES, COMPOUNDS AND METHODS FOR THEIR PREPARATION AND USES THEREOF

CATIONIC ALPHA-AMINO ACID-CONTAINING BIODEGRADABLE POLYMER GENE TRANSFER COMPOSITIONS

piRNA and uses related thereto

FINE PARTICULATE PREPARATION COMPRISING COMPLEX OF NUCLEIC ACID MOLECULE AND COLLAGEN

Methods for identification, and compounds useful for the treatment of degenerative and inflammatory diseases

Methods for the identification of microRNA and their applications in research and human health

siRNA and methods of manufacture

Devices, systems and methods for improving memory and/or cognitive function through brain delivery of siRNA

NOVEL OLIGONUCLEOTIDE COMPOSITIONS AND PROBE SEQUENCES USEFUL FOR DETECTION AND ANALYSIS OF microRNAs AND THEIR TARGET mRNAs

METHODS OF IDENTIFYING GENES INVOLVED IN MEMORY FORMATION USING SMALL INTERFERING RNA(siRNA)

RNA INTERFERENCE USING A UNIVERSAL TARGET

METHODS AND COMPOSITIONS FOR THE SPECIFIC INHIBITION OF GENE EXPRESSION BY DOUBLE-STRANDED RNA

siRNA targeting minichromosome maintenance deficient 3 (MCM3)

METHODS AND COMPOSITIONS FOR THE SPECIFIC INHIBITION OF GENE EXPRESSION BY DOUBLE-STRANDED RNA

Nucleic Acid-Lipopolymer Compositions

Methods and compositions for treating gain-of-function disorders using RNA interference

Composition, method of preparation & application of concentrated formulations of condensed nucleic acids with a cationic lipopolymer

Compositions and methods for enhancing delivery of nucleic acids into cells and for modifying expression of target genes in cells

INTRACELLULAR EXPRESSION AND DELIVERY OF siRNAs IN MAMMALIAN CELLS

METHODS AND COMPOSITIONS FOR THE SPECIFIC INHIBITION OF GENE EXPRESSION BY DOUBLE-STRANDED RNA

RNAi Medicine Having No Adverse Effects

METHODS AND COMPOSITIONS FOR THE SPECIFIC INHIBITION OF GENE EXPRESSION BY DOUBLE-STRANDED RNA

Systems and Methods for Targeted and Controlled Delivery of Agents

siRNA targeting 1-acylglycerol-3-phosphate O-acyltransferase 2 (AGPAT2)

Oligonucleotide compositions and methods for treating disease including inflammatory conditions

METHODS AND COMPOSITIONS FOR THE SPECIFIC INHIBITION OF GENE EXPRESSION BY DOUBLE-STRANDED RNA

RNA interference in respiratory epithelial cells

METHODS AND COMPOSITIONS FOR THE SPECIFIC INHIBITION OF GENE EXPRESSION BY DOUBLE-STRANDED RNA

Compositions and methods for studying and treating inflammatory diseases and disorders

SHRNA AND SIRNA AND MIRNA EXPRESSION IN A LIVING ORGANISM UNDER CONTROL OF A CODON-OPTIMIZED REPRESSOR GENE

RNA Interference Mediated Inhibition of MAP Kinase Gene Expression or Expression of Genes Involved in MAP Kinase Pathway Using Short Interfering Nucleic Acid (SiNA)

RNA interference mediated inhibition of gene expression using chemically modified short interfering nucleic acid (siNA)

Double-Stranded Oligonucleotides

Crosslinking agent, crosslinking method, method of controlling gene expression, and method of examining gene function

Method Of Screening Compound Regulating The Translation Of Specific mRNA

METHODS AND COMPOSITIONS FOR THE SPECIFIC INHIBITION OF GENE EXPRESSION BY DOUBLE-STRANDED RNA

MODIFICATION OF DOUBLE-STRANDED RIBONUCLEIC ACID MOLECULES

System and method for identification of microRNA target sites and corresponding targeting microRNA sequences

BIODEGRADABLE POLYPHOSPHORAMIDATES FOR CONTROLLED RELEASE OF BIOACTIVE SUBSTANCES

Hybrid interfering RNA

Delivery of siRNA by neutral lipid compositions

Short Interfering Rna and Micro-Rna Compounds and Methods of Designing, Making, and Using the Same

ANTI-TUMOR VACCINES DELIVERED BY DENDRITIC CELLS DEVOID OF INTERLEUKIN-10

Use of cytochrome P450 reductase as insecticidal target

siRNA targeting nuclear receptor interacting protein 1 (NRIP1)

siRNa targeting neuropilin 1 (NRP1)

Use of the microRNA miR-1 for the treatment, prevention, and diagnosis of cardiac conditions

Compositions and Methods for Modulating Gene Expression Using Self-Protected Oligonucleotides

Nucleic acid based ladder copolymers

Efficient Method of Preparing Dna Inverted Repeat

Human immunodeficiency virus integrase—Transportin—SR protein—protein interactions

Method for the Production of Suitable Dna Constructs for Specific Inhibition of Gene Expression by Rna Interference

Pre-miRNA loop-modulated target regulation

Methods for Identifying Genes that Mediate a Response of a Living Cell to an Agent

Method of Making an Artificial Nuclease for Anti-viral, Anti-bacterial Applications

siRNA targeting protein kinase N-3 (PKN-3)

Methods and compositions for controlling efficacy of RNA silencing

INTRANASAL DELIVERY OF NUCLEIC ACID MOLECULES

Antisense oligonucleotides against thymidylate synthase

Novel Method of Nucleic Acid Transfer

Amino acid lipids and uses thereof

Treatment of Cancer Using Tlr3 Agonists

WATER SOLUBLE CROSSLINKED POLYMERS

Tetracycline-Dependent Regulation of Rna Interference

Vesicles for active macromolecule delivery

Combined hairpin-antisense compositions and methods for modulating expression

DNA constructs for specific inhibition of gene expression by RNA interference

Antisense Oligonucleotides Directed to Ribonucleotide Reducatase R2 and Uses Thereof in Combination Therapies for the Treatment of Cancer

Bacteria mediated gene silencing

METHODS AND COMPOSITIONS FOR IMPROVED THERAPEUTIC EFFECTS WITH siRNA

Nucleic acid functionalized nanoparticles for therapeutic applications

siRNA targeting proprotein convertase subtilisin/kexin type 9 (PCSK9)

Agents, compositions and methods for treating pathologies in which regulating an ache-associated biological pathway is beneficial

MicroRNA-based methods and compositions for the diagnosis, prognosis and treatment of solid cancers

siRNA targeting vascular endothelial growth factor receptor 1 (VEGFR1)

ENDOGENOUS ANTISENSE RNA EXPRESSION ANALYSIS SYSTEM

Bacterially derived intact minicells that encompass plasmid free functional nucleic acid for in vivo delivery to mammalian cells

Tandem siRNAS

siRNA targeting protein tyrosine phosphatase-1B (PTP1B)

siRNA targeting casitas B cell lymphoma-B (CBL-B)

Multiple shRNA Expression Vectors and Methods of Construction

Injectable Agent for the Targeted Treatment of Retinal Ganglion Cells

Structures of Active Guide Rna Molecules and Method of Selection

Compositions and Method for Brain Specific Targeted Delivery of Therapeutic Agents

Lipids, lipid complexes and use thereof

ShRNA molecules and methods of use thereof

RNA interference mediating small RNA molecules

Target-dependent nucleic acid adapter

Modified Nucleosides for Rna Interference

Chimeric Gapped Oligomeric Compounds

METHODS AND COMPOSITIONS FOR ENHANCING DELIVERY OF DOUBLE-STRANDED RNA OR A DOUBLE-STRANDED HYBRID NUCLEIC ACID TO REGULATE GENE EXPRESSION IN MAMMALIAN CELLS

Method and medicament for inhibiting the expression of a given gene

pRNA chimera

Method and kit for detecting a target protein using a DNA aptamer

TREATMENT OF CANCER USING TLR3 AGONISTS

RNA Interference Mediated Inhibition of Gene Expression Using Short Interfering Nucleic Acid (siNA)

Methods of altering an immune response induced by CpG oligodeoxynucleotides

Modified siRNA molecules and uses thereof

Formulations comprising antisense nucleotides to connexins

Modified Short Interfering Rna (Modified Sirna)

Method for Improved Selection of Rnai Transfectants

Modified polynucleotides for reducing off-target effects in RNA interference

Multi-targeting short interfering RNAs

Inhibiting Gene Expression with dsRNA

Nucleotide-Cochleate Compositions And Methods Of Use

Identification of genetic alterations that modulate drug sensitivity in cancer treatments

Method of designing siRNAs for gene silencing

Methods and compositions for reducing viral genome amounts in a target cell

Inhibitor Nucleic Acids

Antisense guanidinium peptide nucleic acid (GPNA) oligonucleotides as antitumor agents

Method and medicament for inhibiting the expression of a given gene

Method of Treatment by Administration of Rna

siRNA targeting ribonucleotide reductase M2 polypeptide (RRM2 or RNR-R2)

Photocleavable oligonucleotide and uses thereof

CPG-like nucleic acids and methods of use thereof

Cell-Based Rna Interference and Related Methods and Compositions

siRNA targeting cystic fibrosis transmembrane conductance regulator (CFTR)

siRNA targeting ethanolamine Kinase I1 (EKI1)

Inhibiting Gene Expression with dsRNA

Formulations comprising antisense nucleotides to connexins

Vectors and Methods Using Same

Oligonucleotide probes useful for detection and analysis of microRNA precursors

BIOLOGIC MODULATIONS WITH NANOPARTICLES

Products and Methods Related to Mono-Methyl Branched-Chain Fatty Acids

Aptamer-mediated intracellular delivery of oligonucleotides

Triggered RNAi

Method of inducing an immune response

RNAi Agents Comprising Universal Nucleobases

Methods and compositions for RNA interference

Nanoparticles Comprising Rna Ligands

siRNA targeting 5-aminoimidazole-4-carboxamide ribonucleotide formyltransferase/IMP cyclohydrolase (ATIC)

Methods and Compositions for Treating 5Alpha-Reductase Type 1 and Type 2 Dependent Conditions

RNA inteference mediated inhibition of hepatitis C virus (HVC) gene expression using short interfering nucleic acid (siNA)

Compositions and methods for optimizing cleavage of RNA by RNase H

Self-Processing Rna Expression Cassette

Nucleic Acid Complex

Methods and Compositions Relating to Gene Silencing

Single-stranded antimicrobial oligonucleotides and uses thereof

In vivo production of small interfering RNAs that mediate gene silencing

Methods for the Delivery of Oligomeric Compounds

Methods and Compositions for Inhibiting the Function of Polynucleotide Sequences

Rna-Mediated Interference to Control Disease in Terrestrial and Aquaculture Animals

Antibacterial antisense oligonucleotide and method

Highly Potent Hsirna Mixtures and Method for Gene Splicing

Compositions, methods and kits based on small nuclear RNAs

NOVEL GENES AND RNA MOLECULES THAT CONFER STRESS TOLERANCE

siRNA targeting human hairless protein (HR)

siRNA targeting DNA-damage-inducible transcript 4 (DDIT4)

RNA interference mediated inhibition of hypoxia inducible factor 1 (HIF1) gene expression using short interfering nucleic acid (siNA)

Synthetic siRNA compounds and methods for the downregulation of gene expression

BIOINFORMATICALLY DETECTABLE GROUP OF NOVEL HIV REGULATORY GENES AND USES THEREOF

Methods For Gene Targeting

Method and medicament for inhibiting the expression of a given gene

Peptide conjugated, inosine-substituted antisense oligomer compound and method

UNIVERSAL TARGET SEQUENCES FOR siRNA GENE SILENCING

Methods and compositions involving MicroRNA

Lung cancer-related nucleic acids

Methods and compositions for transdermal delivery of nucleotides

siRNA targeting cyclin-dependent kinase inhibitor 1B (p27, Kip1) (CDKN1B)

Allele-specific silencing of disease genes

Methods and compositions involving miRNA and miRNA inhibitor molecules

Method and medicament for inhibiting the expression of a given gene

Method and medicament for inhibiting the expression of a given gene

Methods and compositions involving miRNA and miRNA inhibitor molecules

Methods and Compositions Involving microRNA

Expression system

Highly branched HK peptides as effective carriers of siRNA

Method and medicament for inhibiting the expression of a given gene

siRNA targeting serine/threonine protein kinase AKT

Therapeutic nucleic acid-3′-conjugates

Tat-based immunomodulatory compositions and methods of their discovery and use

Oligonucleotides for RNA interference and biological applications thereof

System and Methods For Short Rna Expression

Efficient process for producing dumbbell DNA

Method of delivering RNA interference and uses thereof

Double-stranded and single-stranded RNA molecules with 5′ triphosphates and their use for inducing interferon

COMPOSITIONS AND METHODS FOR siRNA INHIBITION OF ANGIOGENESIS

Positionally modified siRNA constructs

siRNA targeting synuclein, alpha (SNCA-1)

siRNA targeting myeloid cell leukemia sequence 1

Compositions and Methods That Enhance Rna Interference

siRNA targeting kinase insert domain receptor (KDR)

RNA sequence-specific mediators of RNA interference

Target Cell-Specific Short Interfering Rna and Methods of Use Thereof

Ribonucleic acid interference molecules

RNA interference agents for therapeutic use

SIMULTANEOUS SILENCING AND RESTORATION OF GENE FUNCTION

Stable cell lines and methods for evaluating gastrointestinal absorption of chemicals

Double Strand Compositions Comprising Differentially Modified Strands for Use in Gene Modulation

Clusterin antisense therapy for treatment of cancer

Ultrasound Microbubble Mediated Genes Delivery System

Functional and hyperfunctional siRNA directed against Bcl-2

siRNA targeting interleukin-1 receptor-associated kinase 4 (IRAK4)

siRNA targeting proto-oncogene MET

siRNA targeting myeloid differentiation primary response gene (88) (MYD88)