ClassID:

109048

C12N15/113 - page 15 - CPC Classification

Classification description:

Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor; Recombinant DNA-technology; DNA or RNA fragments; Modified forms thereof Non-coding nucleic acids modulating the expression of genes, e.g. antisense oligonucleotides

Recent Application in this class:
#4201
20210285000
2021-09-16

COMBINATION THERAPY FOR TREATING HEPATITIS B VIRUS INFECTION

#4202
20210284999
2021-09-16

Application of microRNA-210 inhibitor in preparation of drugs for treating inflammatory skin diseases

#4203
20210284998
2021-09-16

Compositions for Transfecting Resistant Cell Types

#4204
20210284974
2021-09-16

COMPOSITIONS AND METHODS FOR THE TREATMENT OF ORNITHINE TRANSCARBAMYLASE DEFICIENCY

#4205
20210284697
2021-09-16

Methods and products for genetic engineering

#4206
20210284680
2021-09-16

ANTISENSE NUCLEIC ACIDS

#4207
20210283186
2021-09-16

Engineered Exosomes for Medical Applications

#4208
20210283170
2021-09-16

METHODS AND COMPOUNDS FOR TREATMENT OF LYMPHOCYTE-RELATED DISEASES AND CONDITIONS

#4209
20210283167
2021-09-16

ALTERING MICROBIAL POPULATIONS & MODIFYING MICROBIOTA

#4210
20210283166
2021-09-16

USE OF MYOSTATIN INHIBITORS AND COMBINATION THERAPIES

#4211
20210283164
2021-09-16

Methods for treating hepatitis B infection

#4212
20210283163
2021-09-16

COMPOSITIONS AND METHODS FOR THE TREATMENT OF ACUTE AND CHRONIC PRURITIS

#4213
20210283108
2021-09-16

METHOD FOR TREATING NEURODEGENERATIVE DISEASES

#4214
20210277421
2021-09-09

Homologous Recombination Reporter Construct and Uses Thereof

#4215
20210277418
2021-09-09

AAV VARIANTS WITH ENHANCED TROPISM

#4216
20210277402
2021-09-09

Targeting microRNA-101-3p in cancer therapy

#4217
20210277398
2021-09-09

Small cell lung cancer therapeutic agent containing oligonucleotide

#4218
20210277397
2021-09-09

Compounds and methods for modulating UBE3A-ATS

#4219
20210277396
2021-09-09

Methods and compositions for sensitization of tumor cells to immune therapy

#4220
20210277395
2021-09-09

Methods and compositions for modulating lncRNAs and methods of treatment based on lncRNA expression

#4221
20210277394
2021-09-09

Short hairpin RNA compositions, methods of making and applications thereof

#4222
20210277389
2021-09-09

Methods and Compositions for the Single Tube Preparation of Sequencing Libraries Using Cas9

#4223
20210277384
2021-09-09

Compositions and methods for evading bacterial defense mechanisms

#4224
20210277371
2021-09-09

ENGINEERING OF SYSTEMS, METHODS AND OPTIMIZED GUIDE COMPOSITIONS WITH NEW ARCHITECTURES FOR SEQUENCE MANIPULATION

#4225
20210277370
2021-09-09

COMPOSITIONS AND METHODS OF USE OF CRISPR-CAS SYSTEMS IN NUCLEOTIDE REPEAT DISORDERS

#4226
20210277078
2021-09-09

FIBER ASSEMBLY AND USE THEREOF

#4227
20210277073
2021-09-09

KIDNEY DISEASE TARGETS AND USES THEREOF

#4228
20210275672
2021-09-09

Compound usable as cationic lipid

#4229
20210275602
2021-09-09

Therapeutic bacterial composition

#4230
20210275600
2021-09-09

Methods for diagnosis and treatment of type 1 diabetes

#4231
20210275566
2021-09-09

COMPOSITIONS FOR CONFERRING TOLERANCE TO VIRAL DISEASE IN SOCIAL INSECTS, AND THE USE THEREOF

#4232
20210275564
2021-09-09

Nucleic acid, pharmaceutical composition and conjugate containing nucleic acid, and use thereof

#4233
20210270845
2021-09-02

MICRORNA-134 BIOMARKER

#4234
20210269866
2021-09-02

CRISPR EFFECTOR SYSTEM BASED AMPLIFICATION METHODS, SYSTEMS, AND DIAGNOSTICS

#4235
20210269803
2021-09-02

OLIGONUCLEOTIDE-BASED PROTEOLYSIS TARGETING CHIMERA

#4236
20210269801
2021-09-02

Methods of Managing Nucleic Acid Replication, Expression, and Cleavage Using CRISPR Associated Nucleases

#4237
20210269800
2021-09-02

RNA MOLECULES COMPRISING NON-CANONICAL BASE PAIRS

#4238
20210269799
2021-09-02

SYNTHETIC GUIDE MOLECULES, COMPOSITIONS AND METHODS RELATING THERETO

#4239
20210269798
2021-09-02

MODIFICATION OF SMALL RNAS FOR THERAPEUTIC USES

#4240
20210269797
2021-09-02

METHODS AND COMPOSITIONS FOR TARGETING PD-L1

#4241
20210269796
2021-09-02

Serpina1 iRNA compositions and methods of use thereof

#4242
20210269790
2021-09-02

Virus-like particles and use thereof

#4243
20210269472
2021-09-02

Compounds and methods for the modulation of proteins

#4244
20210268015
2021-09-02

Sideroflexins as mitochondrial serine transporters

#4245
20210267895
2021-09-02

Lipid formulations for nucleic acid delivery

#4246
20210267893
2021-09-02

Artificial exosome composition and related methods

#4247
20210267216
2021-09-02

Compositions and methods for mitigating pest infestation with

#4248
20210261968
2021-08-26

RNA INTERFERENCE IN DERMAL AND FIBROTIC INDICATIONS

#4249
20210261967
2021-08-26

Compositions and methods of inhibiting gene expression in a lung

#4250
20210261963
2021-08-26

COMPOSITION COMPRISING ANTISENSE OLIGONUCLEOTIDE AND USE THEREOF FOR TREATMENT OF DUCHENNE MUSCULAR DYSTROPHY

#4251
20210261962
2021-08-26

CORRECTION OF DYSTROPHIN EXON 43, EXON 45, OR EXON 52 DELETIONS IN DUCHENNE MUSCULAR DYSTROPHY

#4252
20210261961
2021-08-26

ANTISENSE OLIGONUCLEOTIDES TARGETING TIA1

#4253
20210261960
2021-08-26

METHOD OF USING CUT&RUN OR CUT&TAG TO VALIDATE CRISPR-CAS TARGETING

#4254
20210261959
2021-08-26

Complement component C3 iRNA compositions and methods of use thereof

#4255
20210261945
2021-08-26

Modified compounds and uses thereof

#4256
20210261680
2021-08-26

MUSCLE-TARGETING COMPLEXES AND USES THEREOF

#4257
20210260215
2021-08-26

AAV CARDIAC GENE THERAPY FOR CARDIOMYOPATHY

#4258
20210260209
2021-08-26

ANTIBODY-OLIGONUCLEOTIDE CONJUGATES

#4259
20210260206
2021-08-26

CHIMERIC PEPTIDES FOR ANTISENSE DELIVER

#4260
20210260130
2021-08-26

COMPOSITIONS AND METHODS FOR INHIBITION OF LINEAGE SPECIFIC ANTIGENS

#4261
20210260117
2021-08-26

Modified cells and methods of therapy

#4262
20210260097
2021-08-26

Methods for therapeutic administration of messenger ribonucleic acid drugs

#4263
20210260063
2021-08-26

Pharmaceutical composition for preventing or treating cancer comprising KSP inhibitor and mitosis inhibitor

#4264
20210260002
2021-08-26

METHODS OF TREATING SCHIZOPHRENIA AND OTHER NEUROPSYCHIATRIC DISORDERS

#4265
20210259980
2021-08-26

Compositions and methods for organ specific delivery of nucleic acids

#4266
20210259968
2021-08-26

METHODS AND COMPOSITIONS FOR LOCALIZED AGENT DELIVERY

#4267
20210259218
2021-08-26

Methods of genetic mediated engineering of RNAi models

#4268
20210257504
2021-08-19

ANTI-REFLECTIVE ARTICLES WITH NANOSILICA-BASED COATINGS

#4269
20210254163
2021-08-19

Exonic splicing enhancers and exonic splicing silencers

#4270
20210254161
2021-08-19

METHOD FOR DETERMINING DECREASE IN FUNCTIONS OF HIPPOCAMPUS BY USING CORRELATION BETWEEN MICRO RNA AND NMDA RECEPTOR, METHOD FOR INHIBITING DECREASE IN FUNCTIONS, AND METHOD FOR SCREENING FOR INHIBITORS OF DECREASE IN FUNCTIONS

#4271
20210254101
2021-08-19

METHODS FOR TREATING SPINAL CORD INJURY

#4272
20210254093
2021-08-19

DOWN-REGULATING GENE EXPRESSION IN INSECT PLANTS

#4273
20210254086
2021-08-19

Composition for editing flavonoid biosynthetic gene by using CRISPR/Cas9 system, and use thereof

#4274
20210254076
2021-08-19

TMPRSS6 iRNA COMPOSITIONS AND METHODS OF USE THEREOF

#4275
20210254071
2021-08-19

Oligonucleotide comprising an inosine for treating DMD

#4276
20210254070
2021-08-19

SYSTEMS AND METHODS RELATED TO OLIGONUCLEOTIDE BUFFERS

#4277
20210254069
2021-08-19

COMBINATION THERAPIES COMPRISING C/EBP ALPHA SARNA

#4278
20210254068
2021-08-19

GENOME ENGINEERING PRIMARY MONOCYTES

#4279
20210254067
2021-08-19

MICRORNA INHIBITORS FOR USE IN TREATING METABOLIC DISEASES

#4280
20210254066
2021-08-19

Nucleic acid molecules and uses thereof

#4281
20210254065
2021-08-19

iRNA AGENTS WITH BIOCLEAVABLE TETHERS

#4282
20210254064
2021-08-19

Structurally designed shRNAs

#4283
20210254063
2021-08-19

SERPINC1 iRNA COMPOSITIONS AND METHODS OF USE THEREOF

#4284
20210254062
2021-08-19

OLIGONUCLEOTIDE COMPOSITIONS AND METHODS OF USE THEREOF

#4285
20210254061
2021-08-19

Systems and methods for the treatment of hemoglobinopathies

#4286
20210254060
2021-08-19

MIR-3132 UPREGULATION OF THE TRAIL PATHWAY AND APOPTOTIC ACTIVITY IN CANCER CELLS

#4287
20210254059
2021-08-19

LINKAGE MODIFIED OLIGOMERIC COMPOUNDS

#4288
20210254058
2021-08-19

Short/small hairpin RNA molecules

#4289
20210254057
2021-08-19

Compositions and methods for gene editing by targeting transferrin

#4290
20210254056
2021-08-19

IDENTIFICATION AND TARGETED MODULATION OF GENE SIGNALING NETWORKS

#4291
20210254055
2021-08-19

Single-stranded oligonucleotide

#4292
20210254054
2021-08-19

Artificially-manipulated neovascularization regulatory system

#4293
20210252145
2021-08-19

EPITOPE OF EPB41L5, AND MONOCLONAL ANTIBODY

#4294
20210252039
2021-08-19

Compounds and methods for increasing STMN2 expression

#4295
20210252038
2021-08-19

COMBINATION THERAPIES FOR INNER EAR SENSORY HAIR CELL REGENERATION/REPLACEMENT

#4296
20210251988
2021-08-19

METHODS OF TREATING DISORDERS

#4297
20210246450
2021-08-12

RAAV-based compositions and methods for treating amyotrophic lateral sclerosis

#4298
20210246449
2021-08-12

Antisense oligonucleotides and their use for treating Pendred syndrome

#4299
20210246448
2021-08-12

Composition and methods of RNAi prophylactics and therapeutics for treatment of severe acute respiratory infection caused by 2019 novel coronavirus (2019-nCoV)

#4300
20210246447
2021-08-12

Factor XII (Hageman Factor) (F12), KALLIKREIN B, PLASMA (FLETCHER FACTOR) 1 (KLKB1), and Kininogen 1 (KNG1) iRNA COMPOSITIONS AND METHODS OF USE THEREOF

#4301
20210246446
2021-08-12

tRNA/pre-miRNA compositions and use in treating cancer

#4302
20210246445
2021-08-12

Polynucleotide and method for controlling insect infestation

#4303
20210246444
2021-08-12

Polynucleotide and method used for controlling insect invasion

#4304
20210246443
2021-08-12

Antisense oligonucleotides to restore dysferlin protein expression in dysferlinopathy patient cells

#4305
20210246436
2021-08-12

Electrochemical biosensor

#4306
20210246424
2021-08-12

METHOD OF PRODUCING CAR-T CELLS, NUCLEIC ACID-INTRODUCING CARRIER AND KIT

#4307
20210246193
2021-08-12

Recombinant polypeptide production method

#4308
20210246180
2021-08-12

Methods for expressing proteins in axons

#4309
20210244665
2021-08-12

NEUTRAL LIPOSOMES CONTAINING BIOLOGICALLY ACTIVE AGENTS

#4310
20210241852
2021-08-05

Systems and methods for determining effects of therapies and genetic variation on polyadenylation site selection

#4311
20210238633
2021-08-05

System and Method for the Universal Destruction of Cancer Cells without Toxicity

#4312
20210238628
2021-08-05

ENGINEERED CELLS WITH MODIFIED HOST CELL PROTEIN PROFILES

#4313
20210238604
2021-08-05

USING MICRORNAS TO CONTROL ACTIVATION STATUS OF HEPATIC STELLATE CELLS AND TO PREVENT FIBROSIS IN PROGRESSIVE LIVER DISEASES

#4314
20210238603
2021-08-05

BETA CATENIN NUCLEIC ACID INHIBITOR MOLECULE

#4315
20210238602
2021-08-05

RNAi Agents And Compositions for Inhibiting Expression of Angiopoietin-Like 3 (ANGPTL3), And Methods Of Use

#4316
20210238601
2021-08-05

Oligonucleotide Conjugates

#4317
20210238600
2021-08-05

Bioactive renal cells

#4318
20210238599
2021-08-05

Treatment of ophthalmic conditions with son of Sevenless 2 (SOS2) inhibitors

#4319
20210238598
2021-08-05

COMPOSITIONS, SYSTEMS, AND METHODS FOR BASE DIVERSIFICATION

#4320
20210238597
2021-08-05

Chemically modified single-stranded RNA-editing oligonucleotides

#4321
20210238596
2021-08-05

PHARMACEUTICAL COMPOSITION FOR PREVENTING OR TREATING CANCER, CONTAINING CD300C EXPRESSION INHIBITOR OR ACTIVITY INHIBITOR

#4322
20210238595
2021-08-05

Modified RNA agents with reduced off-target effect

#4323
20210238594
2021-08-05

Compositions and methods for improving strand biased

#4324
20210238593
2021-08-05

MicroRNAs as therapeutic targets for ischemic stroke

#4325
20210238592
2021-08-05

Chimeric RNA-driven genomic rearrangement in mammalian cells

#4326
20210238591
2021-08-05

Selective antisense compounds and uses thereof

#4327
20210238590
2021-08-05

Staufen1 regulating agents and associated methods

#4328
20210238579
2021-08-05

Suppression of shade avoidance response in plants

#4329
20210238557
2021-08-05

Personalized cells, tissues, and organs for transplantation from a humanized, bespoke, designated-pathogen free, (non-human) donor and methods and products relating to same

#4330
20210238556
2021-08-05

Synergistic genome-nonintegrating reprogramming by microRNAs and transcription factors

#4331
20210238552
2021-08-05

EXTRACELLULAR VESICLES LOADED WITH AN EXOGENOUS MOLECULE

#4332
20210238544
2021-08-05

Enhanced placental stem cells and uses thereof

#4333
20210238222
2021-08-05

PRODUCING RECOMBINANT PROTEINS WITH REDUCED LEVELS OF HOST CELL PROTEINS

#4334
20210236653
2021-08-05

Gene therapy for AADC deficiency

#4335
20210236651
2021-08-05

General and direct method for preparing oligonucleotide-functionalized metal-organic framework nanoparticles

#4336
20210236645
2021-08-05

Cationic amphiphilic polymers for codelivery of hydrophobic agents and nucleic acids

#4337
20210236593
2021-08-05

METHODS OF SUPPORTING WEIGHT MAINTENANCE BY DECREASING THE ACTIVITY OF FAM46A

#4338
20210236534
2021-08-05

Compositions and methods for the treatment of expanded repeat-associated disorders

#4339
20210231670
2021-07-29

METHODS OF EVALUATING TREATMENT OUTCOME IN HIGH GRADE SEROUS OVARIAN CANCER

#4340
20210230639
2021-07-29

Methods and compositions for RNA-directed target DNA modification and for RNA-directed modulation of transcription

#4341
20210230632
2021-07-29

COMPOSITIONS AND METHODS FOR DELIVERY OF AAV

#4342
20210230621
2021-07-29

PLANT REGULATORY ELEMENTS AND USES THEREOF

#4343
20210230620
2021-07-29

Plant regulatory elements and uses thereof

#4344
20210230603
2021-07-29

RNAi-MEDIATED INHIBITION OF HIF1A FOR TREATMENT OF OCULAR ANGIOGENESIS

#4345
20210230598
2021-07-29

OLIGONUCLEOTIDES FOR CONTROLLING TAU SPLICING, AND USES THEREOF

#4346
20210230597
2021-07-29

Micro-RNAS and compositions comprising same for the treatment and diagnosis of serotonin-, adrenalin-, noradrenalin-, glutamate-, and corticotropin-releasing hormone- associated medical conditions

#4347
20210230596
2021-07-29

RIG-I Agonists and Methods of Using Same

#4348
20210230595
2021-07-29

BIODEGRADABLE AND CLINICALLY-COMPATIBLE NANOPARTICLES AS DRUG DELIVERY CARRIERS

#4349
20210230594
2021-07-29

COMPOSITIONS AND METHODS FOR CONTROLLING LEPTINOTARSA

#4350
20210230593
2021-07-29

Programmable conditional SIRNAS and uses thereof

#4351
20210230592
2021-07-29

Targeted Self-Assembly of Functionalized Carbon Nanotubes on Tumors

#4352
20210230591
2021-07-29

Methods of reducing virus molecule levels

#4353
20210230590
2021-07-29

Stereospecific linkages in RNA editing oligonucleotides

#4354
20210230589
2021-07-29

Compositions for Modulating C9ORF72 Expression

#4355
20210230588
2021-07-29

Methods and systems of molecular recording by CRISPR-Cas system

#4356
20210230587
2021-07-29

Method for stabilizing nucleic acid nanostructures

#4357
20210230586
2021-07-29

Expanding the chemical substrates for genetic code reprogramming

#4358
20210230256
2021-07-29

NOVEL TARGET FOR ANTI-CANCER AND IMMUNE-ENHANCING

#4359
20210228741
2021-07-29

METHODS AND COMPOSITIONS TO STIMULATE RETINAL REGENERATION

#4360
20210228738
2021-07-29

COMPOSITIONS AND METHODS FOR INCREASING OR ENHANCING TRANSDUCTION OF GENE THERAPY VECTORS AND FOR REMOVING OR REDUCING IMMUNOGLOBULINS

#4361
20210228647
2021-07-29

Mesenchymal stem cell and use thereof for treatment of muscle injury and muscle-associated diseases

#4362
20210228631
2021-07-29

Targeted replacement of endogenous T cell receptors

#4363
20210228629
2021-07-29

ANTI-BCMA CAR-T-CELLS FOR PLASMA CELL DEPLETION

#4364
20210228615
2021-07-29

Oligonucleotide compositions and methods thereof

#4365
20210228614
2021-07-29

LACTATE DEHYDROGENASE A (LDHA) iRNA COMPOSITIONS AND METHODS OF USE THEREOF

#4366
20210228495
2021-07-29

DRUG-LOADED TISSUE ADHESIVE FILM AND PREPARATION METHOD THEREFOR

#4367
20210222205
2021-07-22

Methods and compositions for RNA-directed target DNA modification and for RNA-directed modulation of transcription

#4368
20210222196
2021-07-22

MODIFIED AAV CONSTRUCTS AND USES THEREOF

#4369
20210222176
2021-07-22

POLYNUCLEOTIDE AGENTS TARGETING FACTOR XII (HAGEMAN FACTOR) (F12) AND METHODS OF USE THEREOF

#4370
20210222174
2021-07-22

COMPOSITIONS AND METHODS FOR THE TREATMENT OF ANESTHESIA-INDUCED NEUROTOXICITY

#4371
20210222173
2021-07-22

Compositions and Methods for Lactate Dehydrogenase (LDHA) Gene Editing

#4372
20210222172
2021-07-22

Methods of treating porphyria

#4373
20210222171
2021-07-22

CRISPR/CAS9 SYSTEMS, AND METHODS OF USE THEREOF

#4374
20210222170
2021-07-22

Von Willebrand Factor (VWF)-targeting agents and methods of using the same

#4375
20210222169
2021-07-22

ANTISENSE NUCLEIC ACIDS

#4376
20210222168
2021-07-22

METHODS FOR REACTIVATING GENES ON THE INACTIVE X CHROMOSOME

#4377
20210222167
2021-07-22

SLC2A1 LNCRNA AS A BIOLOGIC AND RELATED TREATMENTS AND METHODS

#4378
20210222166
2021-07-22

LNA BASED NANODEVICE

#4379
20210222150
2021-07-22

GENE-DRIVE IN DNA VIRUSES

#4380
20210222147
2021-07-22

Incorporation of unnatural nucleotides and methods thereof

#4381
20210220387
2021-07-22

PHARMACEUTICAL COMPOSITIONS FOR TREATMENT OF MICRORNA RELATED DISEASES

#4382
20210220386
2021-07-22

EXON SKIPPING OLIGOMERS AND OLIGOMER CONJUGATES FOR MUSCULAR DYSTROPHY

#4383
20210220274
2021-07-22

NOVEL LIPID FORMULATIONS FOR NUCLEIC ACID DELIVERY

#4384
20210214744
2021-07-15

Polynucleotide and method for controlling insect invasion

#4385
20210214728
2021-07-15

COMPOSITIONS FOR DELIVERY OF CARGO TO CELLS

#4386
20210214727
2021-07-15

ENHANCED OLIGONUCLEOTIDES FOR INHIBITING SCN9A EXPRESSION

#4387
20210214726
2021-07-15

Peptide docking vehicle for targeted nucleic acid delivery

#4388
20210214725
2021-07-15

COMPOSITIONS FOR MODULATING EXPRESSION OF C9ORF72 ANTISENSE TRANSCRIPT

#4389
20210214217
2021-07-15

Nucleic acid loaded extracellular vesicles

#4390
20210213136
2021-07-15

Targeting PAX2 for the treatment of breast cancer

#4391
20210213042
2021-07-15

Treatments of non-alcoholic steatohepatitis (NASH)

#4392
20210213041
2021-07-15

REPEAT RNA AS BIOMARKERS OF TUMOR IMMUNE RESPONSE

#4393
20210207203
2021-07-08

CRISPR DOUBLE NICKASE BASED AMPLIFICATION COMPOSITIONS, SYSTEMS, AND METHODS

#4394
20210207169
2021-07-08

VIRAL DELIVERY OF RNA UTILIZING SELF-CLEAVING RIBOZYMES AND CRISPR-BASED APPLICATIONS THEREOF

#4395
20210207141
2021-07-08

Methods and compositions for inhibiting detoxification response

#4396
20210207140
2021-07-08

Non-liposomal systems for nucleic acid delivery

#4397
20210207139
2021-07-08

Programmable and portable CRISPR-Cas transcriptional activation in bacteria

#4398
20210207138
2021-07-08

METHOD FOR EFFICIENT EXON (44) SKIPPING IN DUCHENNE MUSCULAR DYSTROPHY AND ASSOCIATED MEANS

#4399
20210207137
2021-07-08

RNA-INTERFERENCE-INDUCING NUCLEIC ACID MOLECULE ABLE TO PENETRATE INTO CELLS, AND USE THEREFOR

#4400
20210207136
2021-07-08

MYOCARDIAL DYSFUNCTION THERAPEUTIC AGENT

#4401
20210207135
2021-07-08

INHIBITION OF FOLLISTATIN

#4402
20210207130
2021-07-08

METHODS AND COMPOSITIONS FOR THE MAKING AND USING OF GUIDE NUCLEIC ACIDS

#4403
20210207113
2021-07-08

Recruitment of DNA polymerase for templated editing

#4404
20210207093
2021-07-08

Genetically-modified cells comprising a modified human T cell receptor alpha constant region gene

#4405
20210206868
2021-07-08

Method of reducing expression of DUX4 in a muscle cell by administering an anti-transferrin receptor antibody linked to an oligonucleotide targeting DUX4

#4406
20210206848
2021-07-08

RECEPTOR INHIBITION BY PHOSPHATASE RECRUITMENT

#4407
20210205476
2021-07-08

Isolation of novel AAV's and uses thereof

#4408
20210205474
2021-07-08

Senile dementia treatment formulation and application thereof

#4409
20210205380
2021-07-08

ANTIBACTERIAL PHAGE, THERAPEUTIC COMPOSITION, BACTERICIDAL AGENT, FOOD, BACTERIA IDENTIFICATION KIT, THERAPEUTIC COMPOSITION MANUFACTURING METHOD, BACTERIA ELIMINATION METHOD, BACTERIA IDENTIFICATION METHOD, AND ANIMAL THERAPEUTIC METHOD

#4410
20210205229
2021-07-08

MICROENCAPSULATED MODIFIED POLYNUCLEOTIDE COMPOSITIONS AND METHODS

#4411
20210198739
2021-07-01

METHODS FOR DETERMINING THE PRESENCE OR RISK OF DEVELOPING FACIOSCAPULOHUMERAL DYSTROPHY (FSHD)

#4412
20210198699
2021-07-01

KIT FOR REPARING FBN1T7498C MUTATION, COMBINATION FOR MAKING AND REPAIRING MUTATION, AND METHOD OF REPAIRING THEREOF

#4413
20210198696
2021-07-01

Gene editing method using virus

#4414
20210198684
2021-07-01

METHOD FOR INCREASING THE YIELD OF MICROALGAE AND PRODUCTS PRODUCED THEREBY, AN ALTERED CAM1 GENE AND POLYPEPTIDE, AND A NOVEL CHLAMYDOMONAS SP.

#4415
20210198673
2021-07-01

RNA targeting of mutations via suppressor tRNAs and deaminases

#4416
20210198670
2021-07-01

Method for knocking out N-myristoyltransferase (NMT) gene from

#4417
20210198669
2021-07-01

Compositions and methods for treating and preventing muscular disorders and dystrophies, steroid side effects, and inflammation

#4418
20210198668
2021-07-01

Methods and formulations for the treatment of obesity and obesity-related metabolic diseases

#4419
20210198667
2021-07-01

ANTIFIBROTIC AGENT AND BIOMARKER FOR FIBROSIS

#4420
20210198666
2021-07-01

ANTISENSE OLIGONUCLEOTIDES FOR INDUCING EXON SKIPPING AND METHODS OF USE THEREOF

#4421
20210198664
2021-07-01

NOVEL CRISPR-ASSOCIATED SYSTEMS AND COMPONENTS

#4422
20210198641
2021-07-01

MAD nucleases

#4423
20210198636
2021-07-01

Use of Syncytin for Targeting Drug and Gene Delivery to Lung Tissue

#4424
20210198355
2021-07-01

ANTI-IL-23 ANTIBODIES

#4425
20210198328
2021-07-01

MODULATED CAS-INHIBITORS

#4426
20210198323
2021-07-01

RECOMBINANT NEWCASTLE DISEASE VIRUSES AND USES THEREOF FOR THE PREVENTION OF RSV DISEASE OR HUMAN METAPNEUMOVIRUS DISEASE

#4427
20210198306
2021-07-01

Antisense nucleic acids

#4428
20210198305
2021-07-01

OLIGONUCLEOTIDE COMPOSITIONS AND METHODS OF USE THEREOF

#4429
20210196828
2021-07-01

BACTERIAL DELIVERY VEHICLES FOR IN VIVO DELIVERY OF A DNA PAYLOAD

#4430
20210196827
2021-07-01

FUNCTIONAL NUCLEIC ACID HAVING NUCLEOSIDE ANALOG DRUG INTEGRATED INTO SKELETON, DERIVATIVE AND USE THEREOF

#4431
20210196750
2021-07-01

Liposomal-gold nanoparticles for drug delivery into the brain

#4432
20210189460
2021-06-24

SEQUENTIAL PAIRED-END SEQUENCING

#4433
20210189435
2021-06-24

System for DNA editing and uses thereof

#4434
20210189432
2021-06-24

COMPOSITIONS AND METHODS OF USE OF ARC CAPSIDS

#4435
20210189430
2021-06-24

AAV vectors for retinal and CNS gene therapy

#4436
20210189426
2021-06-24

CRISPR INTERFERENCE BASED HTT ALLELIC SUPPRESSION AND TREATMENT OF HUNTINGTON DISEASE

#4437
20210189416
2021-06-24

Creation of herbicide resistant gene and use thereof

#4438
20210189403
2021-06-24

Expression from transposon-based vectors and uses

#4439
20210189395
2021-06-24

Composition for preventing or treating neurodegenerative disease

#4440
20210189394
2021-06-24

Targeting ligands for therapeutic compounds

#4441
20210189393
2021-06-24

COMPOSITIONS AND METHODS FOR INHIBITING EXPRESSION OF FACTOR V

#4442
20210189392
2021-06-24

S-ANTIGEN TRANSPORT INHIBITING OLIGONUCLEOTIDE POLYMERS AND METHODS

#4443
20210189391
2021-06-24

Programmed cell death 1 ligand 1 (PD-L1) iRNA compositions and methods of use thereof

#4444
20210189390
2021-06-24

Combination treatment for cystic fibrosis

#4445
20210189389
2021-06-24

METHODS OF MODULATING ANK1

#4446
20210189388
2021-06-24

DNA-guided gene editing and regulation

#4447
20210189375
2021-06-24

Method for regulating gene expression

#4448
20210189352
2021-06-24

ENHANCED REPROGRAMMING OF SOMATIC CELLS

#4449
20210189342
2021-06-24

COMPOSITIONS AND METHODS FOR MODULATING MONOCYTE AND MACROPHAGE INFLAMMATORY PHENOTYPES AND IMMUNOTHERAPY USES THEREOF

#4450
20210188895
2021-06-24

SINGLE-STRANDED NUCLEIC ACID MOLECULE, AND PRODUCTION METHOD THEREFOR

#4451
20210187125
2021-06-24

COMPOSITIONS AND METHODS FOR GENE EDITING FOR HEMOPHILIA A

#4452
20210187116
2021-06-24

Compositions and methods of treating muscle atrophy and myotonic dystrophy

#4453
20210187083
2021-06-24

Modified factor VII polypeptides for subcutaneous administration and on-demand treatment

#4454
20210187040
2021-06-24

IPSC-DERIVED SECRETOME COMPOSITIONS, AND RELATED SYSTEMS AND METHODS

#4455
20210187018
2021-06-24

CYTOBIOLOGICS AND THERAPEUTIC USES THEREOF

#4456
20210187007
2021-06-24

C/EBP ALPHA SARNA COMPOSITIONS AND METHODS OF USE

#4457
20210187003
2021-06-24

EXON SKIPPING OLIGOMERS FOR MUSCULAR DYSTROPHY

#4458
20210186934
2021-06-24

COMPOSITIONS AND USES THEREOF

#4459
20210186029
2021-06-24

Control of plant pests using RNA molecules

#4460
20210180085
2021-06-17

Transgene cassettes designed to express a human MECP2 gene

#4461
20210180066
2021-06-17

Compositions and methods for inhibiting gene expression of Hif2alpha

#4462
20210180065
2021-06-17

Antisense oligonucleotides targeting alpha-synuclein and uses thereof

#4463
20210180064
2021-06-17

Exon skipping compositions for treating muscular dystrophy

#4464
20210180063
2021-06-17

ANTI-ARID3A TREATMENTS FOR INFLAMMATORY DISORDERS

#4465
20210180062
2021-06-17

Modulating SYNGAP

#4466
20210180061
2021-06-17

Methods and compositions for the specific inhibition of alpha-1 antitrypsin by double-stranded RNA

#4467
20210180060
2021-06-17

MULTIPLE EXON SKIPPING COMPOSITIONS FOR DMD

#4468
20210180059
2021-06-17

COMPOSITIONS AND METHODS FOR IMPROVING THE EFFICACY OF CAS9-BASED KNOCK-IN STRATEGIES

#4469
20210180058
2021-06-17

Methods and compositions for studying cell evolution

#4470
20210180057
2021-06-17

MODULATORS OF ENaC EXPRESSION

#4471
20210180056
2021-06-17

Method for treating cancer by disabling-BRCA1/FANCM interaction

#4472
20210180055
2021-06-17

Systems and methods for gene modification

#4473
20210180031
2021-06-17

RECOMBINANT AAVS HAVING USEFUL TRANSCYTOSIS PROPERTIES

#4474
20210180017
2021-06-17

Enhanced immune effector cells and use thereof

#4475
20210180016
2021-06-17

PLATELETS LOADED WITH mRNA

#4476
20210180014
2021-06-17

Method of assessing activity of recombinant antigen receptors

#4477
20210179720
2021-06-17

Nucleic acid-polypeptide compositions and uses thereof

#4478
20210179659
2021-06-17

ANTISENSE NUCLEIC ACIDS

#4479
20210177984
2021-06-17

Skin-permeating carrier containing nucleic acid complex and use thereof

#4480
20210177884
2021-06-17

COMPLEMENT COMPONENT C5 iRNA COMPOSITIONS AND METHODS OF USE THEREOF

#4481
20210177770
2021-06-17

POROUS SILICON MATERIALS COMPRISING A METAL SILICATE FOR DELIVERY OF THERAPEUTIC AGENTS

#4482
20210172008
2021-06-10

METHODS AND COMPOSITIONS TO IDENTIFY NOVEL CRISPR SYSTEMS

#4483
20210171983
2021-06-10

Genomic safe harbors for genetic therapies in human stem cells and engineered nanoparticles to provide targeted genetic therapies

#4484
20210171970
2021-06-10

Increasing plant oil content by altering a negative regulator of acetyl-CoA carboxylase

#4485
20210171967
2021-06-10

bZIP transcription factors regulate conversion of nicotine to nornicotine

#4486
20210171955
2021-06-10

Angiopoietin-like 3 (ANGPTL3) iRNA compositions and methods of use thereof

#4487
20210171954
2021-06-10

Angiopoietin-like 3 (ANGPTL3) iRNA compositions and methods of use thereof

#4488
20210171949
2021-06-10

Targeting Mirnas for Exosomal Delivery or Cellular Retention

#4489
20210171948
2021-06-10

COMPOSITIONS AND METHODS FOR TARGETING GLYPICAN-2 IN THE TREATMENT OF CANCER

#4490
20210171947
2021-06-10

Recruitment methods and compounds, compositions and systems for recruitment

#4491
20210171946
2021-06-10

COMPLEMENT COMPONENT C5 iRNA COMPOSITIONS AND METHODS OF USE THEREOF FOR TREATING PAROXYSMAL NOCTURNAL HEMOGLOBINURIA (PNH)

#4492
20210171945
2021-06-10

METHODS OF MODULATING ANTISENSE ACTIVITY

#4493
20210171944
2021-06-10

Compositions and methods for modulating gene expression

#4494
20210171932
2021-06-10

Polyanionic acids to improve recovery and minimize system loss

#4495
20210171923
2021-06-10

MAD nucleases

#4496
20210171615
2021-06-10

Use of SRSF3 agents for the treatment and/or prevention of neurological conditions, cancer, bacterial infections or viral infections

#4497
20210169974
2021-06-10

Compounds for use in the treatment of telomere related diseases and/or telomere related medical conditions

#4498
20210169919
2021-06-10

EXON SKIPPING OLIGOMER CONJUGATES FOR MUSCULAR DYSTROPHY

#4499
20210169917
2021-06-10

Conjugated Antisense Compounds for Use in Therapy

#4500
20210169916
2021-06-10

METHODS FOR REDUCING C9ORF72 EXPRESSION