109048 ⎘
Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor; Recombinant DNA-technology; DNA or RNA fragments; Modified forms thereof Non-coding nucleic acids modulating the expression of genes, e.g. antisense oligonucleotides
MicroRNA fingerprints during human megakaryocytopoiesis
#10802Treatment of hepatocyte growth factor (HGF) related diseases by inhibition of natural antisense transcript to HGF
#10803Treatment of uncoupling protein 2 (UCP2) related diseases by inhibition of natural antisense transcript to UCP2
#10804MicroRNA fingerprints during human megakaryocytopoiesis
#10805THERAPEUTIC AGENT FOR FIBROID LUNG
#10806Pharmaceutical Composition Comprising miRNA-100 And Its Use in the Modulation Of Blood Vessel Growth and Endothelial Inflammation
#10807Modified siRNA molecules and uses thereof
#10808Methods for treating and/or limiting development of diabetes
#10809MicroRNA fingerprints during human megakaryocytopoiesis
#10810Method for treating myocardial infarct
#10811Duplex oligonucleotide complexes and methods for gene silencing by RNA interference
#10812Treatment of pancreatic developmental gene related diseases by inhibition of natural antisense transcript to a pancreatic developmental gene
#10813Oral delivery of therapeutically effective LNA oligonucleotides
#10814TRPM-2 antisense therapy
#10815METHODS AND COMPOSITIONS FOR ENHANCING THE EFFICACY AND SPECIFICITY OF SINGLE AND DOUBLE BLUNT-ENDED siRNA
#10816Compositions and methods for diagnosing and treating melanoma
#10817Down-regulating gene expression in insect pests
#10818Compositions and methods for inhibiting expression of the HAMP gene
#10819Methods and compositions for the inhibition of Stat5 in prostate cancer cells
#10820Composition containing inhibitors of the expression or activity of SH3RF2 for preventing or treating cancer
#10821MOLECULAR TARGETS FOR HEALING OR TREATING WOUNDS
#10822Use of Kif13A and AP-1 inhibitors for inhibiting melanogenesis
#10823Compositions and methods for identifying and targeting cancer cells of alimentary canal origin
#10824Modulation of pre-mRNA using splice modulating oligonucleotides as therapeutic agents in the treatment of disease
#10825METHODS AND COMPOSITIONS FOR TREATING INSECTS
#10826MODULATION OF APOLIPOPROTEIN(A) EXPRESSION
#10827SENESCENCE MARKER, METHOD FOR EVALUATING SENESCENCE INHIBITOR, AND CANCER INHIBITOR
#10828Low density lipoprotein receptor-mediated siRNA delivery
#10829Methods for Modulation of Autophagy Through the Modulation of Autophagy-Inhibiting Gene Products
#10830Treatment of pyrroline-5-carboxylate reductase 1 (PYCR1) related diseases by inhibition of natural antisense transcript to PYCR1
#10831Delivery of dsRNA to arthropods
#10832RNAI IN BUDDING YEAST
#10833Use of miR-30e to treat vascular lesions
#10834COMPOSITIONS AND METHODS FOR SIRNA INHIBITION OF HIF-1 ALPHA
#10835METHODS FOR TREATING DISEASES
#10836USE OF GILZ PROTEIN EXPRESSED IN DENDRITIC CELLS TO MODULATE AN ANTIGEN-SPECIFIC IMMUNE RESPONSE
#10837CONJUGATES, PARTICLES, COMPOSITIONS, AND RELATED METHODS
#10838Tetrary gene delivery system for gene therapy and methods of its use
#10839Methods for Modulation of Autophagy Through the Modulation of Autophagy-Enhancing Gene Products
#10840Th1-associated microRNAs and their use for tumor immunotherapy
#10841INHIBITION OF CHOROIDAL NEOVASCULARIZATION
#10842Plants resistant to insect pests
#10843Morpholino-based antisense agent
#10844Recurrent gene fusions in prostate cancer
#10845AGENTS, COMPOSITIONS AND METHODS FOR TREATING PATHOLOGIES IN WHICH REGULATING AN ACHE-ASSOCIATED BIOLOGICAL PATHWAY IS BENEFICIAL
#10846Targeting microRNAs for the treatment of liver cancer
#10847Treatment of interferon regulatory factor 8 (IRF8) related diseases by inhibition of natural antisense transcript to IRF8
#10848Treatment of tumor protein 63 (p63) related diseases by inhibition of natural antisense transcript to p63
#10849TREATMENT OF FILAGGRIN (FLG) RELATED DISEASES BY MODULATION OF FLG EXPRESSION AND ACTIVITY
#10850Microrna-based methods and compositions for the diagnosis, prognosis and treatment of tumor involving chromosomal rearrangements
#10851Recurrent gene fusions in prostate cancer
#10852Method of diagnosing and treating cancer using B-catenin splice variants
#10853Lipid formulated compositions and methods for inhibiting expression of transthyretin (TTR)
#10854TREATMENT OF INSULIN RECEPTOR SUBSTRATE 2 (IRS2) RELATED DISEASES BY INHIBITION OF NATURAL ANTISENSE TRANSCRIPT TO IRS2 AND TRANSCRIPTION FACTOR E3 (TFE3)
#10855Peptide oligonucleotide conjugates
#10856Synthetic mimics of miR-34
#10857Stabilized STAT3 decoy oligonucleotides and uses therefor
#10858Antibodies that bind polypeptides involved in the process of bone remodeling
#10859Plants with useful traits and related methods
#10860Reduction of off-target RNA interference toxicity
#10861Method of inhibiting miR-33 using a modified oligonucleotide
#10862Modulation of eIF4E expression
#10863siRNA Targeting Glucagon Receptor (GCCR)
#10864MicroRNA Signatures Associated with Human Chronic Lymphocytic Leukemia (CLL) and Uses Thereof
#10865Sirna compounds comprising terminal substitutions
#10866siRNA targeting amyloid beta (A4) precursor protein (APP)
#10867FUNCTIONS AND TARGETS OF LET-7 MICRO RNAS
#10868Lipid formulated compositions and methods for inhibiting expression of Eg5 and VEGF genes
#10869COMPOSITIONS AND METHODS RELATED TO MIRNA IN DIABETIC CONDITIONS
#10870Cochleate compositions directed against expression of proteins
#10871Anti-IL-23 antibodies
#10872ANTI-NEOPLASTIC USES OF ARTEMIN ANTAGONISTS
#10873METHOD AND COMPOSITION FOR CREATING CONDITIONAL LETHALITY FOR VIRUS MUTANTS AND FOR ELIMINATING THE VIABILITY OF AN EUKARYOTIC CELL
#10874Down-regulation of a homeodomain-leucine zipper I-class homeobox gene for improved plant performance
#10875Treatment of sex hormone binding globulin (SHBG) related diseases by inhibition of natural antisense transcript to SHBG
#10876Means and methods for the specific modulation of target genes in the CNS and the eye and methods for their identification
#10877CONTROL OF GENE EXPRESSION
#10878Modulation of signal transducer and activator of transcription 3 (STAT3)expression
#10879MicroRNA-10 antagonists and MicroRNA-10 targets for use in the treatment of a glioma
#10880NOVEL COMPOUNDS FOR MODULATING NEOVASCULARISATION AND METHODS OF TREATMENT USING THESE COMPOUNDS
#10881MicroRNA Mediated Neuronal Cell Induction
#10882Synthetic mimics of MIR-124
#10883Nucleic acid-containing lipid particles and related methods
#10884MicroRNA compositions and methods for enhancing plant resistance to abiotic stress
#10885METHODS AND COMPOSITIONS FOR DYSFERLIN EXON-SKIPPING
#10886MODULATION OF TTC39 EXPRESSION TO INCREASE HDL
#10887MICRORNA COMPOUNDS AND METHODS FOR MODULATING MIR-21 ACTIVITY
#10888Polyamides for nucleic acid delivery
#10889SiRNA targeting apolipoprotein (APOB)
#10890Antisense molecules and methods for treating pathologies
#10891Oligomeric compounds for the modulation of HIF-1A expression
#10892siRNA Targeting Diacylglycerol O-Acyltransferase Homolog 2 (DGAT2)
#10893Alternative export pathways for vector expressed RNA interference
#10894Method for analyzing secretome, biomarker for lung cancer metastasis, and siRNA compound for inhibiting lung cancer metastasis
#10895MicroRNA-140-5p as a tumor suppressor and sensitizing agent for chemotherapy
#10896Methods for treating chronic obstructive pulmonary disease
#10897Reversible platelet inhibition
#10898SiRNA targeting cyclin-dependent kinase inhibitor 1B (p27, Kip1) (CDKN1B)
#10899Treatment of nuclear respiratory factor 1 (NRF1) related diseases by inhibition of natural antisense transcript to NRF1
#10900Method for introducing siRNA into cells by photochemical internalisation
#10901OLIGOMERIC COMPOUNDS AND EXCIPIENTS
#10902Methods and compositions for eliciting an immune response against hepatitis B virus
#10903APTAMER-TARGETED SIRNA TO INHIBIT NONSENSE MEDIATED DECAY
#10904MULTIPLEX DICER SUBSTRATE RNA INTERFERENCE MOLECULES HAVING JOINING SEQUENCES
#10905Molecule for treating an inflammatory disorder
#10906siRNA targeting kinase insert domain receptor (KDR)
#10907siRNA Targeting Proto-oncogene MET
#10908Systems and methods for individualized functional genomic profiling related to cancer cell growth
#10909Compositions for controlling mites in bees
#10910Methods and compositions for the specific inhibition of gene expression by double-stranded RNA
#10911METHOD OF DELIVERING RNA INTERFERENCE AND USES THEREOF
#10912Sequence diversity generation in immunoglobulins
#10913NUCLEIC ACID PROBE-BASED DIAGNOSTIC ASSAYS TARGETING SSRA GENES OF PROKARYOTIC AND EUKARYOTIC ORGANISMS
#10914MicroRNA as a cancer progression predictor and its use for treating cancer
#10915Method of regulating gene expression
#10916Therapeutic agent for tumor
#10917Oligonucleotide complex compositions and methods of use as gene alteration tools
#10918Modulation of huntingtin expression
#10919Trans-acting RNA switches
#10920Methods and compositions for treating diseases, disorders or injury of the CNS
#10921siRNA Targeting Interleukin-1 Receptor-associated Kinase 4 (IRAK4)
#10922RNAi modulation of APOB and uses thereof
#10923Nucleic acid silencing sequences
#10924Method for rapidly evaluating performance of short interfering RNA with novel chemical modifications
#10925Materials and methods useful for affecting tumor cell growth, migration and invasion
#10926Composition for treatment of pancreatic cancer
#10927Bi-functional shRNA targeting Stathmin 1 and uses thereof
#10928Method for diagnosis/prognosis of cancers using an epigenetic marker consisting of a specific single CpG site in TTP promoter and treatment of cancers by regulating its epigenetic status
#10929Plant regulatory elements and uses thereof
#10930RNA-INTERFERENCE BY SINGLE-STRANDED RNA MOLECULES
#10931RNAi-mediated inhibition of HIF1A for treatment of ocular angiogenesis
#10932Compositions and methods for treatment of neuropathic pain
#10933COMPOSITIONS AND METHODS FOR DELIVERING RNAI USING APOE
#10934Methods and kits to identify invasive glioblastoma
#10935Methods and systems for identifying micro-RNA targets and synthesizing novel micro-RNAs and uses of the same
#10936Human microRNAs and methods for inhibiting same
#10937Methods for increasing efficacy of lipid formulated siRNA
#10938METHODS AND COMPOSITIONS FOR MAINTENANCE OF A FUNCTIONAL WOUND
#10939Micro-RNA for the regulation of cardiac apoptosis and contractile function
#10940Antisense oligonucleotides for inhibition of microRNA-21
#10941Methods of identifying modulators of TDP-43 mediated cellular toxicity
#10942Amphiphilic nucleotide cochleate compositions and methods of using the same
#10943Gene expression and pain
#10944Multi-targets interfering RNA molecules and their applications
#10945Compositions and methods for prognosis and treatment of prostate cancer
#10946Treatment of vasculoproliferative conditions with Lrg1 anatgonists
#10947Brachyury polypeptides and methods for use
#10948Methods of Modulating the Sex of Avians
#10949Compositions and methods for inhibiting expression of transthyretin
#10950CONJUGATES, PARTICLES, COMPOSITIONS, AND RELATED METHODS
#10951Compositions and methods for treating cancer and other diseases
#10952FRA-1 TARGET GENES AS DRUG TARGETS FOR TREATING CANCER
#10953AGENTS USEFUL IN TREATING FACIOSCAPULOHUMERAL MUSCULAR DYSTROPHY
#10954Cancer Specific Mitotic Network
#10955Treatment of cancer by inhibition of IGFBPs and clusterin
#10956Use of two microRNA moleculars in lung cancer prognosis and medicine preparation
#10957siRNA targeting catenin, Beat-1 (CTNNB1)
#10958Anti-miR-1 Therapy for Wound Healing
#10959METHODS AND COMPOSITIONS FOR TREATING NEUROLOGICAL DISEASE
#10960Methods for Diagnosing Stomach Cancer Using MicroRNA Signatures
#10961Methods for Diagnosing Prostate Cancer Using MicroRNA Signatures
#10962Methods for diagnosing lung cancer using MicroRNA signatures
#10963Methods for diagnosing colon cancer using MicroRNA signatures
#10964Methods for Diagnosing Breast Cancer Using MicroRNA Signatures
#10965Methods for diagnosing stomach cancer using MicroRNAs
#10966Methods for diagnosing prostate cancer using MicroRNAs
#10967Methods for diagnosing pancreatic cancer using MicroRNAs
#10968Methods for diagnosing lung cancer using microRNAs
#10969Methods for diagnosing colon cancer using MicroRNAs
#10970Methods for diagnosing breast cancer using MicroRNAs
#10971Methods for diagnosing pancreatic cancer using miR-103-1, miR-103-2, miR-24-2 and miR-107
#10972Methods for Diagnosing Breast Cancer Using miR-21, miR-125-1, miR-125b-2 and miR-145
#10973Methods for Diagnosing Colon, Stomach, Prostate and Pancreas Cancer Using miR-223
#10974Methods for Diagnosing Breast and Lung Cancer Using miR-210 and miR-213
#10975Methods for diagnosing breast, colon, lung, pancreatic and prostate cancer using miR-21 and miR-17-5p
#10976COMPOSITIONS AND METHODS FOR MODULATING STEM CELLS AND USES THEREOF
#10977Exon skipping therapy for dysferlinopathies
#10978COMPOUNDS AND METHODS FOR MODULATING EXPRESSION OF GCGR
#10979MODULATION OF GLUT4 GENE PROMOTER ACTIVITY BY AHNAK
#10980IFN TYPE-I PRODUCTION INHIBITOR AND METHOD FOR SCREENING FOR SAME
#10981Compositions of a peptide targeting system for treating cancer
#10982Innate immune suppression enables repeated delivery of long RNA molecules
#10983Diagnostic and treatment for chronic and acute phase myeloid leukemia
#10984Virion Derived Protein Nanoparticles For Delivering Diagnostic Or Therapeutic Agents For The Treatment Of Non-Melanoma Skin Cancer
#10985REPROGRAMMING COMPOSITIONS AND METHODS OF USING THE SAME
#10986Compositions and methods for therapy of macular degeneration
#10987Antisense oligonucleotide modulation of STAT3 expression
#10988RNAi probes targeting cancer-related proteins
#10989Treatment of inflammatory diseases using miR-124
#10990Antisense oligonucleotides
#10991MITOCHONDRIAL FUNCTION OF PROHIBITIN 2 (PHB2)
#10992Method for screening anticancer agent or SIP1/ZEB2 inhibitor using integrin alpha 5
#10993Use of eIF3m for the diagnosis and treatment of cancer
#10994BIOLOGICAL MARKERS PREDICTIVE OF ANTI-CANCER RESPONSE TO INSULIN-LIKE GROWTH FACTOR-1 RECEPTOR KINASE INHIBITORS
#10995Promoters exhibiting endothelial cell specificity and methods of using same
#10996Agents that reduce neuronal overexcitation
#10997Therapeutic and diagnostic molecules
#10998Methods and products for expression of micro RNAs
#10999Mitochondrial function of prohibitin 2 (PHB2)
#11000Oligonucleotides inhibiting cellular migration
#11001Selecting and stabilizing dsRNA constructs
#11002MIRNA INHIBITION OF SIX1 EXPRESSION
#11003Compositions and methods for modulation of SMN2 splicing in a subject
#11004TREATMENT OF PATIENTS AFTER STENT IMPLANTATION OR BALLOON DILATATION AND DRUG ELUTING STENTS
#11005Promoter variants for expressing genes in a fungal cell
#11006COMBINATORIAL ENGINEERING
#11007Short RNA mimetics
#11008Use of MicroRNA for treating diseases associated with a dysfunction of the cilia in multiciliated epithelial cells
#11009Polynucleotides for multivalent RNA interference, compositions and methods of use thereof
#11010Oligoribonucleotides and methods of use thereof for treatment of alopecia, acute renal failure and other diseases
#11011MicroRNA inhibitors comprising locked nucleotides
#11012Compositions and methods for silencing apolipoprotein C-III expression
#11013SiRNA targeting connective tissue growth factor (CTGF)
#11014ANTISENSE INHIBITION VIA RNASE H-INDEPENDENT REDUCTION IN MRNA
#11015Construction of bifunctional short hairpin RNA
#11016Lipid formulation
#11017Lipid formulations for nucleic acid delivery
#11018Treatment of immune disorders with Hom-1 inhibitors
#11019KIDNEY DISEASE TARGETS AND USES THEREOF
#11020SPARC ANTISENSE COMPOSITIONS AND USES THEREOF
#11021MOLECULAR TARGETS FOR TREATMENT OF INFLAMMATION
#11022Ubiquitin promoter and methods of use
#11023MicroRNA-24
#11024Animal models of neurological disorders
#11025Nucleic acids encoding peptides for treating wounds, anti-angiogenic compounds and uses thereof
#11026RNAi-mediated inhibition of frizzled related protein-1 for treatment of glaucoma
#11027siRNA phospholipid conjugate
#11028Methods and compositions for treating and diagnosing diseases
#11029Compositions and methods for treatment, diagnosis and prognosis of mesothelioma
#11030Recombinant DNA molecule encoding 5′ UTR capable of preventing inhibition of translation under environmental stresses
#11031Method for the preparation of micro-RNA and its therapeutic application
#11032Exon Skipping Therapy for Functional Amelioration of Semifunctional Dystrophin in Becker and Duchenne Muscular Dystrophy
#11033Bicyclic cyclohexose nucleic acid analogs
#11034METHODS AND KITS FOR LINKING POLYMORPHIC SEQUENCES TO EXPANDED REPEAT MUTATIONS
#11035Host cell protein knock-out cells for production of therapeutic proteins
#11036METHODS FOR THE IDENTIFICATION OF MICRORNA AND THEIR APPLICATIONS IN RESEARCH AND HUMAN HEALTH
#11037Further use of protein kinase N beta
#11038TREATMENT OF COLLAGEN GENE RELATED DISEASES BY INHIBITION OF NATURAL ANTISENSE TRANSCRIPT TO A COLLAGEN GENE
#11039Polynucleotide comprising sequences of wheat gliadins and use thereof for silencing by RNAi
#11040Regulatory nucleic acid molecules for enhancing constitutive gene expression in plants
#11041SnoRNAi-small nucleolar RNA degradation by RNA interference in trypanosomatids
#11042Chemical modification of short small hairpin RNAs for inhibition of gene expression
#11043Modulation of exportin 5 expression
#11044Spinal muscular atrophy (SMA) treatment via targeting of SMN2 splice site inhibitory sequences
#11045Use of inhibitors of Zdhhc2 activity for modulation of adipogenesis
#11046General composition framework for ligand-controlled RNA regulatory systems
#11047Expanding hematopoietic stem cells
#11048Oligomeric compounds and compositions for use in modulation of small non-coding RNAs
#11049Preventing and Curing Beneficial Insect Diseases Via Plant Transcribed Molecules
#110505′ phosphate mimics
#11051Targeting EN2, PAX2, and/or DEFB1 for treatment of prostate conditions
#11052REPROGRAMMING CANCER CELLS
#11053Therapeutic uses of inhibitors of RTP801
#11054COMPOSITIONS AND METHODS FOR THE TREATMENT OF KRABBE AND OTHER NEURODEGENERATIVE DISEASES
#11055Insect pest control method
#11056Method and system for monitoring nutritional uptake as a function of microflora intestinal gas levels
#11057MICRONEEDLE ARRAYS FOR ACTIVE AGENT DELIVERY
#11058MODULATION OF EIF4E-BP2
#11059Disabling autophagy as a treatment for lysosomal storage diseases
#11060TRICYCLO-DNA ANTISENSE OLIGONUCLEOTIDES, COMPOSITIONS, AND METHODS FOR THE TREATMENT OF DISEASE
#11061Methods for modulating the expression and aggregation of CAG-expanded gene product in cells and methods for identifying agents useful for doing the same
#11062Nucleic acid based fluorescent sensor for mercury detection
#11063MODULATION OF TRANSTHYRETIN EXPRESSION
#11064INHIBITION OF MIGRATION INHIBITORY FACTOR IN THE TREATMENT OF DISEASES INVOLVING CYTOKINE-MEDIATED TOXICITY
#11065CHEMICAL MODIFICATIONS MOTIFS FOR MIRNA INHIBITORS AND MIMETICS
#11066Methods, systems, and compositions for neuronal differentiation of multipotent stromal cells
#11067Lepidopteran moth control using double-stranded RNA constructs
#11068Formicidae (ant) control using double-stranded RNA constructs
#11069Methods for treating nicotinic acetylcholine receptor associated diseases
#11070Sphingosine-bound siRNA
#11071SOLUBLE THF RECEPTORS AND THEIR USE IN TREATMENT OF DISEASE
#11072Treatment of down syndrome gene related diseases by inhibition of natural antisense transcript to a down syndrome gene
#11073RNAi Modulation of AHA and Therapeutic Uses Thereof
#11074MODULATION OF TIMP1 AND TIMP2 EXPRESSION
#11075Diagnosis and treatment of adrenocortical tumors using human microRNA-483
#11076Treatment of 'IQ motif containing GTPase activating protein' (IQGAP) related diseases by inhibition of natural antisense transcript to IQGAP
#11077NON HUMAN ANIMAL MODELS FOR INCREASED RETINAL VASCULAR PERMEABILITY
#11078Oligonucleotide end caps
#11079Inhibitors of heat shock RNA
#11080Targeted integration into the PPP1R12C locus
#11081Modified siNA
#11082Technology for the Preparation of Microparticles
#11083Means and methods for counteracting, delaying and/or preventing adverse energy metabolism switches in heart disease
#11084Methods for treating chronic kidney disease
#11085Methods for genetic control of insect infestation in plants and compositions thereof
#11086SiRNA targeting catenin, beta-1 (CTNNB1)
#11087Screening for compounds that modulate GPR3-mediated beta-arrestin signaling and amyloid beta peptide generation
#11088ANTISENSE OLIGONUCLEOTIDES (ODN) AGAINST SMAD7 AND USES THEREOF IN MEDICAL FIELD
#11089Single nucleotide polymorphism (SNP) targeting therapies for the treatment of huntington'S disease
#11090Treatment of ‘C terminus of HSP70-interacting protein’ (CHIP)related diseases by inhibition of natural antisense transcript to CHIP
#11091siRNA targeting spleen tyrosine kinase
#11092ANTIGENE LOCKS AND THERAPEUTIC USES THEREOF
#11093Synthetic genes and genetic constructs
#11094UNC-45A splice variants based cancer diagnostics and therapeutics
#11095miR-31 in duchenne muscular dystrophy therapy
#11096MODIFIED OLIGONUCLEOTIDES FOR TELOMERASE INHIBITION
#11097Treatment of Adiponectin related diseases by inhibition of natural antisense transcript to an Adiponectin
#11098Cell-targeting nanoparticles comprising polynucleotide agents and uses thereof
#11099Organic compositions to treat HSF1-related diseases
#11100Organic compositions to treat HSF1-related diseases