Nucleic acid molecules and their use in therapy

Agents and methods to elicit anti-tumor immune response

Screening method for pain suppressor and pharmaceutical composition for prevention or treatment of pain

METHODS FOR IDENTIFYING THERAPEUTIC AGENTS WHICH INTERACT WITH STK24

HYBRID FORMULATION OF RESPONSIVE POLYMERIC NANOCARRIERS FOR THERAPEUTIC AND DIAGNOSTIC DELIVERY

RNAI APPROACH FOR CROP PEST PROTECTION

Compositions and methods for inhibition of the lncRNA SAF to drive apoptotic cell death in human immunodeficiency virus (HIV) infected human macrophages

Anti-inflammatory treatment via inhibition of endothelial cell kinesin light chain 1, variant 1 (KLC1C)

COMPOSITIONS AND METHODS FOR INHIBITING EXPRESSION OF THE ALAS1 GENE

NUCLEIC ACIDS COMPRISING IMPREFECT HAIRPINS

Gene-regulating compositions and methods for improved immunotherapy

Collagen-mimetic peptide mediated delivery of nucleic acid carriers for efficient delivery from collagen

Modulators of FOXP3 expression

USP30 INHIBITORS AND METHODS OF USE

Ketohexokinase (KHK) iRNA compositions and methods of use thereof

NANOCOMPOSITES FOR IMAGING AND DRUG DELIVERY

METHODS OF MODULATING PROTEIN EXPRESSION FROM THE MENA-RIBONUCLEOPROTEIN COMPLEX IN CELLS

GENES AND POLYMORPHISMS ASSOCIATED WITH AGE RELATED MACULAR DEGENERATION (AMD)

COTL1 protein involved in maintaining homeostasis of hematopoietic stem cell, and use thereof

Compositions and methods for controlling

Oligonucleotide compounds for treatment of preeclampsia and other angiogenic disorders

Methods for inhibition of HAO1 (hydroxyacid oxidase 1 (glycolate oxidase)) gene expression

RNAi-MEDIATED INHIBITION OF HIF1A FOR TREATMENT OF OCULAR ANGIOGENESIS

Core master regulators of glioblastoma stem cells

Virus like particle

INHIBITION OF VASCULAR ENDOTHELIAL CELL-MEDIATED PHAGOCYTIC PROCESSES FOR TREATMENT OF DEMYELINATING CONDITIONS

COMPOSITION AND METHOD OF USING MIR-302 PRECURSORS AS ANTI-CANCER DRUGS FOR TREATING HUMAN LUNG CANCER

Mammalian cells for producing a secreted protein

LncRNAs for therapy and diagnosis of cardiac hypertrophy

PUM 1 protein as target for virus inhibition

COMPOSITION FOR DELIVERING PHYSIOLOGICALLY ACTIVE INGREDIENTS INTO BLOOD VESSEL

Polypeptides having beta-xylosidase activity and polynucleotides encoding same

RNAi inhibition of alpha-ENaC expression

Tumor associated vaccines and compositions for disrupting tumor-derived immunosuppression for use in combination cancer immunotherapy

Compositions and methods of treating amyotrophic lateral sclerosis (ALS)

Oligonucleotide compositions and methods of use thereof

EXOSOME LOADED THERAPEUTICS FOR THE TREATMENT OF NON-ALCOHOLIC STEATOHEPATITIS, DIABETES MELLITUS TYPE 1 AND TYPE 2, ATHEROSCLEROTIC CARDIOVASCULAR DISEASE, AND ALPHA 1 ANTITRYPSIN DEFICIENCY

Use of therapeutic agents

Modulating RNA Interactions with Polycomb Repressive Complex 1 (PRC1)

Antisense therapies for treating cancer

DEVICE AND METHOD FOR PROMOTING RAPID STRUT COVERAGE AND VASCULAR ENDOTHELIAL COVERAGE

Fungal immunogens and related materials and methods

Safe lentiviral vectors for targeted delivery of multiple therapeutic molecules

TRPC3 as a therapeutic target for alzheimer's disease

Use of potassium channel inhibitor for treating depression

METHODS AND COMPOSITIONS RELATING TO ANTI-CALCIFICATION

Modulatory polynucleotides

Control of insect infestation

Methods of expanding hematopoietic stem cells, compositions, and methods of use thereof

Anti-PVRIG antibodies and methods of use

Antibodies and processes for preparing the same

COMPOSITIONS AND METHODS FOR ENHANCING THE THERAPEUTIC POTENTIAL OF STEM CELLS

Methods and compositions for the treatment of retinopathy and other ocular diseases

Methods and compositions for the treatment of retinopathy and other ocular diseases

METHODS FOR ALTERING GENE EXPRESSION FOR GENETIC DISORDERS

DOWN-REGULATING GENE EXPRESSION IN INSECT PLANTS

Methods and compositions for treating a proprotein convertase subtilisin kexin (PCSK9) gene-associated disorder

Fidgetin-like 2 as a target to enhance wound healing

COMPOSITIONS AND METHODS FOR TREATING CANCER

Angiopoietin-like 3 (ANGPTL3) iRNA compositions and methods of use thereof

Hepatitis B virus (HBV) iRNA compositions and methods of use thereof

Therapeutic agent for a lung disease and/or method for screening for the same

Long non-coding RNA in cancer

IncRNAs GADLOR 1 and 2 for use in treating and preventing cardiac remodelling

METHOD OF SYNTHESIS OF AN IONIZABLE CATIONIC LIPID

Cationic sulfonamide amino lipids and amphiphilic zwitterionic amino lipids

Lipid compositions

Nutlin-3a for treatment of proliferative vitreoretinopathy

Silencing of HNF4A-P2 isoforms with siRNA to improve hepatocyte function in liver failure

Treatment of Sirtuin (SIRT) related diseases by inhibition of natural antisense transcript to a Sirtuin (SIRT)

Molecules and agents for treating hepatitis B virus

Factor XII (hageman factor) (F12), kallikrein B, plasma (fletcher factor) 1 (KLKB1), and kininogen 1 (KNG1) iRNA compositions and methods of use thereof

SHIP INHIBITION TO INDUCE EXPRESSION OF GRANULOCYTE COLONY STIMULATING FACTOR IN A SUBJECT

Molecular system for cancer biology

Compositions and methods of treating amyotrophic lateral sclerosis (ALS)

siRNA Targeting LDHA

Enhanced organogenesis through manipulation of LIN28/LET-7/DIS3L2

TREATMENT OF ANGIOGENESIS-ASSOCIATED DISEASES USING RNA COMPLEXES THAT TARGET ANGPT2 AND PDGFB

Treatment strategies against anthrax by interfering with critical host factors

GENE THERAPY TARGETING THE NEONATAL FORM OF NAV1.5 FOR TREATING CANCER

Modified oligonucleotides targeting SNPs

GENETICALLY MODIFIED NK-92 CELLS WITH DECREASED CD96/TIGIT EXPRESSION

Methods for reducing post-operative cognitive dysfunction (POCD)

Double-stranded nucleic acid molecule, DNA, vector, cancer cell growth inhibitor, cancer cell migration inhibitor, and drug

PANCREATIC CANCER TARGETS AND USES THEREOF

Modulation of angiopoietin-like 3 expression

NOVEL LIPID FORMULATIONS FOR NUCLEIC ACID DELIVERY

HIV pre-immunization and immunotherapy

Treatment of atopic dermatitis and asthma using RNA complexes that target IL4Rα, TRPA1, or F2RL1

In vivo delivery of oligonucleotides

Variant RNAi

Gemcitabine Derivatives for Cancer Therapy

Functional Nucleic Acid Protective Vector Based On DNA Hydrogel, Preparation Method and Application Thereof

Methods for overcoming glucocorticoid resistance and for determining glucocorticoid resistance potential in cancer

EXOSOME LOADED THERAPEUTICS FOR TREATING SICKLE CELL DISEASE

Methods of treating cancer having an active Wnt/β-catenin pathway

COMPOSITIONS AND METHODS FOR PRODUCING EXOSOME LOADED THERAPEUTICS FOR TREATING CARDIOVASCULAR DISEASE

COMPOSITIONS AND METHODS FOR NUCLEIC ACID AND/OR PROTEIN PAYLOAD DELIVERY

Method for inhibiting calcification of a smooth muscle cell (SMC)

COMPOSITIONS AND METHODS OF TREATMENT FOR LYTIC AND LYSOGENIC VIRUSES

Methods for Producing Enteroendocrine Cells That Make and Secrete Insulin

Methods and compositions for managing vascular conditions

Products and compositions

POLYNUCLEOTIDE AGENTS TARGETING COMPLEMENT COMPONENT C5 AND METHODS OF USE THEREOF

TREATMENT OF A DISEASE OF THE GASTROINTESTINAL TRACT WITH A CHST15 INHIBITOR

METHODS FOR TREATING AND PREVENTING ALLERGIES AND ACUTE ALLERGIC RESPONSES

ERBB3 Activators in Hearing Restoration

Methods and compositions for the treatment of retinopathy and other ocular diseases

Stable transformation of a population and a method of biocontainment using haploinsufficiency and underdominance principles

Compositions and methods for treating phenylketonuria

COMPOUNDS TARGETING LONG NON CODING RNA FOR THE TREATMENT OF CANCER

SYSTEMS

O-methyl rich fully stabilized oligonucleotides

Vista modulators for diagnosis and treatment of cancer

Use of alphavirus in preparation of antitumor drugs

TARGETING NR3B1 FOR TREATMENT OF NASH

CO-DELIVERY OF NUCLEIC ACIDS FOR SIMULTANEOUS SUPPRESSION AND EXPRESSION OF TARGET GENES

NANOSCALE CARRIERS FOR THE DELIVERY OR CO-DELIVERY OF CHEMOTHERAPEUTICS, NUCLEIC ACIDS AND PHOTOSENSITIZERS

Inhibition of Chemokine CCL7 or Receptor CCR3 of Same for the Treatment and Diagnosis of Prostate Cancer

PROSTATIC CANCER MARKER, PLXNA1, AND APPLICATION THEREOF

METHODS OF DIAGNOSING AND TREATING ALZHEIMER'S DISEASE

Methods and compositions for RNA-directed target DNA modification and for RNA-directed modulation of transcription

RNAi strategies for control of whitefly

Methods for Treating Obesity of a Subject Suffering from Obesity

APOLIPOPROTEIN C3 (APOC3) iRNA COMPOSITIONS AND METHODS OF USE THEREOF

Twist signaling inhibitor compositions and methods of using the same

Cationic lipid

Serpina1 iRNA compositions and methods of use thereof

A METHOD FOR REGULATING THE FUNCTION OF A HEART CELL, RELATED NUCLEOTIDES AND COMPOUNDS

Therapeutic drug for Alport's syndrome

Anti-LILRB antibodies and their use in detecting and treating cancer

RENAL CLEARABLE DRUG DELIVERING NANOPARTICLES AND METHODS OF USE THEREFOR

Gene therapies for lysosomal disorders

SYSTEM AND METHODS FOR THE BIOCONTROL OF PLANT PATHOGENS

Engineered immunostimulatory bacterial strains and uses thereof

Compositions of asymmetric interfering RNA and uses thereof

COMPLEMENT COMPONENT C5 iRNA COMPOSITIONS AND METHODS OF USE THEREOF

Staufen1 agents and associated methods

MicroRNA (miRNA) and Downstream Targets for Diagnostic and Therapeutic Purposes

HYBRID EXOSOMAL-POLYMERIC (HEXPO) NANO-PLATFORM FOR DELIVERY OF RNAI THERAPEUTICS

Methods and compositions for the activation of gamma-delta T-cells

Methods of treating cancer harboring hemizygous loss of TP53

Prevention and/or treatment of inflammatory skin disease

DELIVERY OF THERAPEUTIC AGENT

Products and compositions

Therapeutic alteration of transplantable tissues through in situ or ex vivo exposure to RNA interference molecules

Compositions of asymmetric interfering RNA and uses thereof

Nucleic acid molecules encoding an engineered antigen receptor and an inhibitory nucleic acid molecule and methods of use thereof

Method of delivering genes and drugs to a posterior segment of an eye

Compositions for facilitating membrane fusion and uses thereof

Haploid induction compositions and methods for use therefor

Methods for detection of RNase activity

Targeted nanocarriers for the administration of immunosuppressive agents

Compounds and methods for reducing ATXN2 expression

LONG NON-CODING RNA USED FOR ANTICANCER THERAPY

COMPOSITIONS AND METHODS FOR INHIBITIION OF EXPRESSION OF PROTEIN C (PROC) GENES

COMPOSITIONS AND METHODS OF TREATING CANCER

Oligonucleotide compositions and methods thereof

Agents and methods for treating and preventing seborrheic keratosis

Dually derivatized chitosan nanoparticles and methods of making and using the same for gene transfer in vivo

Compositions comprising bacterially derived minicells and methods of using the same

Application of PDCD4 as a therapeutic target for antidepressants and/or anxiolytics drugs

COMPOSITIONS AND METHODS FOR ANALYZING HETEROGENEOUS SAMPLES

RNAi-MEDIATED INHIBITION OF HIF1A FOR TREATMENT OF OCULAR ANGIOGENESIS

Novel Structurally Designed shRNAs

Inhibition of serotonin expression in gut enteroendocrine cells results in conversion to insulin-positive cells

NOVEL USE OF REGULATORY T CELL-SPECIFIC SURFACE PROTEIN LRIG-1

Peptide-polynucleotide complex for polynucleotide transfection

METHOD FOR DETERMINING, PREDICTING AND TREATING CANCER

Mutant calreticulin for the diagnosis of myeloid malignancies

Compositions and methods for the treatment of hypercholesterolemia

Gene silencing

Multimodal cancer therapy comprising chimeric viral/nonviral nanoparticles and anticancer agents

COMPOSITIONS AND METHODS FOR MODULATING AN IMMUNE RESPONSE

Synergistic combination of oligonucleotides and chemotherapeutic for treating cancer

Particles and compositions comprising the same for transfection

Method for diagnosis, prognosis and determination of treatment for cutaneous t-cell lymphoma

Biomarkers And Targets For Proliferative Diseases

COMPOSITIONS, METHODS AND KITS FOR CHARACTERIZING AND SCREENING FOR SMALL CELL OVARIAN CARCINOMA

Methods of treating cancers containing fusion genes

NUCLEIC ACID DELIVERY CARRIER, NUCLEIC ACID DELIVERY KIT, AND NUCLEIC ACID DELIVERY METHOD

NUCLEIC ACID CAPABLE OF INHIBITING EXPRESSION OF MASP2

Treatment of CNS injury with RNAi therapeutics

Treatment of down syndrome gene related diseases by inhibition of natural antisense transcript to a down syndrome gene

Methods and compositions for controlling efficacy of RNA silencing

Complement component C5 iRNA compositions and methods of use thereof

COMPLEMENT COMPONENT C5 IRNA COMPOSITIONS AND METHODS OF USE THEREOF

RAAV-based compositions and methods for treating amyotrophic lateral sclerosis

Polypeptides having cellulolytic enhancing activity and polynucleotides encoding same

Lin28-mediated control of let-7 biogenesis

Methods of treating cancer by administering inhibitory RNA molecules targeting protease serine 2 (PRSS2) expression

Compositions and methods for the delivery of nucleic acids

LIGAND-MODIFIED DOUBLE-STRANDED NUCLEIC ACIDS

Inhibition of stress granule formation through manipulation of UBAP2L

Methods of treating or alleviating joint diseases by administering an inhibitor of discoidin domain receptor 1 (DDR1)

GFI1 inhibitors for the treatment of hyperglycemia

METHODS AND COMPOSITIONS FOR ENHANCING THE EFFICACY AND SPECIFICITY OF SINGLE AND DOUBLE BLUNT-ENDED siRNA

RNA interference for the treatment of gain-of-function disorders

COMPOSITIONS AND METHODS FOR MODULATING AN IMMUNE RESPONSE

KINASE AND UBIQUITIN LIGASE INHIBITORS AND USES THEREOF

Liposomal particles, methods of making same and uses thereof

Methods of treating porphyria

Compositions comprising alternating 2′-modified nucleosides for use in gene modulation

Arrays of memory cells individually comprising a capacitor and an elevationally-extending transistor, methods of forming a tier of an array of memory cells, and methods of forming an array of memory cells individually comprising a capacitor and an elevationally-extending transistor

STAT5a AND ITS FUNCTIONAL TUMOR SUPPRESSOR ANALOGS FOR TREATMENT OF MALIGNANCIES EXPRESSING NPM/ALK AND OTHER ONCOGENIC KINASES

Method for assessing the efficacy of IMiDs and composition or combination for use in treating IMiD sensitive diseases

Engineered cells with decreased gene expression resulting in increased viral production

Capped cyclodextrin-hydrophobic moiety conjugate, cyclodextrin supramolecular polymer, and cyclodextrin-siRNA complex and method of synthesis thereof

THERAPIES BASED ON CONTROL OF REGULATORY T CELL STABILITY AND FUNCTION VIA A NEUROPILIN-1:SEMAPHORIN AXIS

METHOD FOR MAINTAINING INCREASED INTRACELLULAR p53 LEVEL, INDUCED BY PLATINUM-BASED ANTICANCER DRUG, AND APPLICATION THEREOF

METHODS OF INHIBITING CANCER STEM CELLS WITH HMGA1 INHIBITORS

Tobacco plant and production method thereof

Cytotoxic T cell response modifiers

Methods and compositions for the specific inhibition of glycolate oxidase (HAO1) by double-stranded RNA

HIPPO AND DYSTROPHIN COMPLEX SIGNALING IN CARDIOMYOCYTE RENEWAL

Reduced size self-delivering RNAI compounds

Costimulatory B7-H1 in renal cell carcinoma patients: indicator of tumor aggressiveness and potential therapeutic target

EFFICIENT PROTEIN EXPRESSION IN VIVO USING MODIFIED RNA (MOD-RNA)

METHODS OF TREATMENT FOR CANCER, STEROL HOMEOSTASIS, AND NEUROLOGICAL DISEASES

MARKERS SELECTIVELY DEREGULATED IN TUMOR-INFILTRATING REGULATORY T CELLS

Compositions and methods for the production of pyruvic acid and related products using dynamic metabolic control

P-coumaroyl-CoA:monolignol transferase

REDUCTION OF LIPASE ACTIVITY IN PRODUCT FORMULATIONS

Interfering RNA molecules

Methods and compositions for the specific inhibition of alpha-1 antitrypsin by double-stranded RNA

3′ end caps for RNAi agents for use in RNA interference

Nucleic acid constructs and methods of using the same

Methods and compositions for the activation of gamma-delta T-cells

Compositions and methods for treating endometriosis

Methods for sub-typing and treating cancer

Asymmetric siRNA for inhibiting expression of male pattern hair loss target gene

Methods of using PVT1 exon 9 to diagnose and treat prostate cancer

Chemically-modified siRNA

Compositions and methods for treating and preventing pancreatitis, renal injury and cancer

Isolated mammalian somatic cells containing modified RNA encoding OCT4, SOX2, and KLF4

METHODS AND COMPOSITIONS FOR TREATMENT OF IONIZING RADIATION RESISTANT TUMORS

Methods of Treating Angiogenesis-Related Disorders Using JNK3 Inhibitors

DIAGNOSTIC AND SCREENING METHODS FOR ATOPIC DERMATITIS

RNAi therapy for treatment and/or prevention of glaucoma

Genetic and pharmacological transcriptional upregulation of the repressed FXN gene as a therapeutic strategy for Friedreich ataxia

MUCOSAL HEALING PROMOTER

siRNA sequence-independent modification formats for reducing off-target phenotypic effects in RNAI, and stabilized forms thereof

IncRNAS for therapy and diagnosis of angiogenesis

Engineered natural killer (NK) cells and compositions and methods thereof

METHODS AND COMPOSITIONS FOR TREATING SOLID TUMORS AND ENHANCING TUMOR VACCINES

Car t-cells comprising inactivated CBL and CBL-B genes

Compositions and related methods for modulating endosymbionts

Methods and compositions for treating malignant tumors associated with KRAS mutation

Treatment of idiopathic pulmonary fibrosis using RNA complexes that target connective tissue growth factor

Method for assaying MicroRNA, cancer therapeutic agent, and medical composition containing same for cancer therapy

Nucleotide sequence and method for controlling insect infestation

METHODS OF TREATING NEURODEGENERATIVE DISEASES BY INDUCING DISEASE-ASSOCIATED MICROGLIA (DAM) CELLS

Recombinant polypepties for membrane fusion and uses thereof

METHOD OF ELIMINATING STEM CELLS

Compositions and methods for regulating body weight and metabolic syndromes

Fusion genes associated with progressive prostate cancer

BIOLOGICAL CONTROLS OF COLEOPTERAN PESTS

Composition and method for oligonucleotide delivery

Adjustable method for sustainable human cognitive enhancement

Compositions and methods for inhibiting gene expression of factor XII

Antibody targeting IL-13RA2 and use thereof

Compositions and methods for treating and preventing inflammation

Rspondins as modulators of angiogenesis and vasculogenesis

Lipids and lipid compositions for the delivery of active agents

Serpina1 siRNAs: compositions of matter and methods of treatment

CD2-associated protein (CD2AP) and its interactive proteins

Angiopoietin-like 3 (ANGPTL3) iRNA compositions and methods of use thereof

Polycationic methyl phospholipids for improved delivery of nucleic acids to eukaryotic cells

STRUCTURES AND METHODS FOR GENE THERAPY

Multifunctional RNA nanoparticles and methods for treating cancer and therapeutic resistant cancer

METHODS FOR TREATING OR PREVENTING TTR-ASSOCIATED DISEASES USING TRANSTHYRETIN (TTR) iRNA COMPOSITIONS

Methods and Compositions for Selecting siRNA of Improved Functionality

METHODS AND PHARMACEUTICAL COMPOSITIONS FOR MODULATING STEM CELLS PROLIFERATION OR DIFFERENTIATION

Modified iRNA agents

Nucleic acid simultaneously inhibiting expression of mTOR gene and STAT3 gene

Transthyretin (TTR) iRNA compositions and methods of use thereof for treating or preventing TTR-associated diseases

HYBRID NUCLEIC ACID MOLECULES AND THEIR USE

Therapeutic targets for facioscapulohumeral muscular dystrophy

Application of ERH Gene in the Preparation of Bladder Cancer Diagnosis and Treatment Products

TREATMENT OF SARCOMA

Compositions and methods for reactivating latent immunodeficiency virus

RNAi-MEDIATED INHIBITION OF HIF1A FOR TREATMENT OF OCULAR ANGIOGENESIS

IMMUNOMODULATION BY CONTROLLING ELR+ PROINFLAMMATORY CHEMOKINE LEVELS WITH THE LONG NON-CODING RNA UMLILO

Method of making peptide-tagged PEGylated chitosan nanoparticles

USE OF HYDROGEN SULFIDE SYNTHESIS INHIBITORS FOR CANCER THERAPY

Methods and compositions for RNA-directed target DNA modification and for RNA-directed modulation of transcription

RNA INTERFERENCE MEDIATED INHIBITION OF CATENIN (CADHERIN-ASSOCIATED PROTEIN), BETA 1 (CTNNB1) GENE EXPRESSION USING SHORT INTERFERING NUCLEIC ACID (SINA)

Methods and materials for treating cancer

SUGAR CHAIN-RELATED GENE AND USE THEREOF

Endosomal cleavable linkers

Consequences of a defective switch in cutaneous squamous cell carcinoma

MICRORNAS DIFFERENTIALLY EXPRESSED IN PANCREATIC DISEASES AND USES THEREOF

ENHANCED HETATOPOIETIC STEM CELL TRANSPLANTATION

METHODS FOR ENHANCING VASCULAR DENSITY

Methods of treatment of viral infection and uses of anti-HSC70 inhibitors

Methods of treating mitochondrial dysfunction

SiRNA structures for high activity and reduced off target

Therapeutic inhibition of lactate dehydrogenase and agents therefor

ANTISENSE OLIGONUCLEOTIDES DIRECTED AGAINST CONNECTIVE TISSUE GROWTH FACTOR AND USES THEREOF

Compositions and methods for treating cancer by inhibiting PIWIL4