YEAST FOR PRODUCING AND DELIVERING RNA BIOACTIVE MOLECULES AND METHODS AND USES THEREOF

Nucleic acid simultaneously inhibiting expression of mTOR gene and STAT3 gene

Antitumor compounds and tumor diagnosis

COMPLEX OF POLYSACCHARIDE AND DOUBLE-STRANDED RNA AND METHOD OF INHIBITING EXPRESSION OF A TARGET GENE IN A CELL

Methods for preventing ischemia reperfusion injury in an organ with antibody antagonists of IL-33

METHOD OF PRODUCING LEUKOCYTES USING PTPN2 INHIBITION FOR ADOPTIVE CELL TRANSFER

Liposomal particles, methods of making same and uses thereof

METHODS FOR TREATING OVARIAN CANCER

Variant RNAi

COMPOSITIONS AND METHODS FOR TREATING HYPERTRIGLYCERIDEMIA

Angiotensinogen (AGT) iRNA compositions and methods of use thereof

Fungal immunogens and related materials and methods

Activating chimeric receptors and uses thereof in natural killer cell immunotherapy

Method of treating infection or its associated symptoms

SERPINA1 SIRNAS: COMPOSITIONS OF MATTER AND METHODS OF TREATMENT

Method to enhance the transcription regulation of SUPT4H on genes containing repetitive nucleotide sequences

Method of treating inflammatory bowel disease (IBD), irritable bowel syndrome (IBS) or gluten hypersensitivity by administering an elastase 2A (ELA2A) inhibitor

Method of targeting senescent cells

Lipid-derived neutral nanoparticles

GENE THERAPEUTIC FOR THE TREATMENT OF HIV AND USES THEREOF

Transgenic microalgae and use thereof as a feed for delivery of interfering RNA molecules

Nucleic acid, composition and conjugate containing nucleic acid, preparation method therefor and use thereof

Peptides and nanoparticles for intracellular delivery of molecules

Compositions and methods for transport across the blood brain barrier

APPLICATION OF A NANO RNAi PREPARATION IN PVY PREVENTION AND CONTROL

Enhancing radiation sensitivity comprising administering PMVK inhibiting siRNA and shRNA

Methods of Modulating Lymphangiogenesis, E.g., to Treat Corneal Transplant Rejection, in a Subject

Fully stabilized asymmetric siRNA

Gene therapeutics for treating bone disorders

Block copolymers

METHOD OF DIAGNOSIS, PROGNOSIS OR TREATMENT OF NEURODEGENERATIVE DISEASES

Systems, methods and composition of using RNase III mutants to produce sRNA to control host pathogen infection

Inhibitors of micro-RNA 22

Micro-RNA and obesity

Modified double-stranded RNA agents

Reelin antibodies for treatment of atherosclerosis

METHODS FOR TREATING ALCOHOLIC LIVER DISEASE, ALCOHOL-INDUCED BRAIN INJURY AND REDUCING ALCOHOL ADDICTION

COLON DISEASE TARGETS AND USES THEREOF

Compositions and methods for the treatment of a beta-catenin-associated disease or disorder

Gene therapies for lysosomal disorders

PEANUT WITH REDUCED ALLERGEN LEVELS

Modification of immune cells for reducing toxicity and uses thereof in adoptive cell therapy

REDUCING CUTANEOUS SCAR FORMATION AND TREATING SKIN CONDITIONS

Systemic delivery of myostatin short interfering nucleic acids (siNA) conjugated to a lipophilic moiety

Treatment of ophthalmic conditions with angiopoietin-like 7 (ANGPTL7) inhibitors

Methods and compositions for the activation of gamma-delta T-cells

PREVENTION OR TREATMENT OF CHRONIC ORGAN INJURY

Gene therapy of the FAAH pseudogene

Methods of treating cancer by inhibiting SETD2

COMPOSITIONS AND METHODS FOR TREATING GRAVES DISEASE

Sterol regulatory element binding protein (SREBP) chaperone (SCAP) iRNA compositions and methods of use thereof

Method of synthesis of an ionizable cationic lipid

EXOSOME TRANSFER OF NUCLEIC ACIDS TO CELLS

Fatty acids and their use in conjugation to biomolecules

Immunomodulatory small hairpin RNA molecules

Methods and pharmaceutical compositions for treating tubulin carboxypeptidases associated diseases

Targeted compositions

COMPOUNDS OF CHEMICALLY MODIFIED OLIGONUCLEOTIDES AND METHODS OF USE THEREOF

A DBAIT MOLECULE AGAINST ACQUIRED RESISTANCE IN THE TREATMENT OF CANCER

CONTROL OF INSECT PESTS USING RNA MOLECULES

Compositions and methods of treating muscle atrophy and myotonic dystrophy

System for the biocontrol of white spot syndrome virus (WSSV) in aquaculture

Method of reducing the effects of aging-associated impairment of neurogenesis comprising modulating c-c chemokine receptor type 3 (CCR3)

Treatment of angiopoietin like 7 (ANGPTL7) related diseases

Deoxynucleic Guanidines (DNG)- Modified Oligonucleotides and Methods of Synthesizing Deoxynucleic Guanidine Strands

SLIT AND BONE GROWTH MODULATION

NOVEL RNAi MOLECULE DELIVERY PLATFORM BASED ON SINGLE-siRNA AND shRNA NANOCAPSULES

Method for diagnosis of Alzheimer's disease using microRNA

TMPRSS6 iRNA compositions and methods of use thereof

MODULATORS OF DNM2 EXPRESSION

RNAi-MEDIATED INHIBITION OF HIF1A FOR TREATMENT OF OCULAR ANGIOGENESIS

Pharmaceutical compositions and methods of use for activation of human fibroblast and myofibroblast apoptosis

Methods relating to circulating tumor cell clusters and the treatment of cancer

Short interfering nucleic acid (siNA) compositions

POLYNUCLEOTIDE CONSTRUCTS HAVING BIOREVERSIBLE AND NON-BIOREVERSIBLE GROUPS

Modulating Immune Responses

Compounds and methods for trans-membrane delivery of molecules

Compositions and methods for treating HIF-1a over-expressing cancers

Methods of treating wounds using cathepsin K inhibitors

Method for inhibiting the expression of inflammation promoting factors

H-1 PV EXPRESSING RNAI EFFECTORS TARGETING CDK9

METHODS OF MODULATING ALK

Una amidites and uses thereof

KISSPEPTIN 1 (KISS1) IRNA COMPOSITIONS AND METHODS OF USE THEREOF

THERAPEUTIC AND DIAGNOSTIC METHODS RELATING TO CANCER STEM CELLS

PVRIG polypeptides and methods of treatment

Nucleoside derivative and use thereof

Nucleic acid-polypeptide compositions and uses thereof

Decreasing lactate level and increasing polypeptide production by downregulating the expression of lactate dehydrogenase and pyruvate dehydrogenase kinase

COMPOSITIONS AND METHODS FOR INHIBITING EXPRESSION OF MUTANT EGFR GENE

Inhibitor for use for preventing and/or treating an infection with hepatitis B virus

Reprogramming of non-neuronal cells into neurons and methods and compositions to treat neurodegenerative diseases and disorders

CTLA-4 aptamer conjugates

Transthyretin (TTR) iRNA compositions and methods of use thereof for treating or preventing TTR-associated diseases

RUNX1 inhibition for treatment of proliferative vitreoretinopathy and conditions associated with epithelial to mesenchymal transition

Reducing beta-catenin expression to potentiate immunotherapy

Concatemeric RNA molecules, compositions, and methods and uses thereof

Modulating dsRNA editing, sensing, and metabolism to increase tumor immunity and improve the efficacy of cancer immunotherapy and/or modulators of intratumoral interferon

Targeting cell tropism receptors to inhibit cytomegalovirus infection

C/EBP alpha saRNA compositions and methods of use

SHIP INHIBITION TO COMBAT OBESITY

NANOCARRIERS AND THEIR PROCESSING FOR DIAGNOSTICS AND THERAPEUTICS

MRGPRX2/MRGPRB2 EXPRESSING CELL BASED ASSAY TO DETECT PSEUDO-ALLERGIC DRUG REACTIONS AND TO IDENTIFY BLOCKERS TO PREVENT THE ADVERSE REACTIONS

METHOD OF TREATING TYPE II DIABETES AND OBESITY AND METHOD OF SCREENING A MEDICAMENT FOR THE SAME

METHODS AND COMPOSITIONS FOR EXPANSION OF CELL POPULATION

Genetically-modified immune cells comprising a microRNA-adapted shRNA (shRNAmiR)

Nucleic acid-containing lipid nanoparticle

Methods and compositions for RNA-directed target DNA modification and for RNA-directed modulation of transcription

Fibrotic treatment

Methods of inducing insulin production

Localized therapy of lower airways inflammatory disorders with proinflammatory cytokine inhibitors

METHODS AND MODIFICATIONS THAT PRODUCE ssRNAi COMPOUNDS WITH ENHANCED ACTIVITY, POTENCY AND DURATION OF EFFECT

Peptide phosphorodiamidate morpholino oligomers plant delivery to reduce pathogens and insect pests

BIOLOGICAL MATERIALS AND USES THEREOF

Nucleic acid, composition and conjugate containing same, preparation method, and use thereof

Compositions and methods for treating motor neuron diseases

ROR2 inhibitors and use thereof in treating and/or preventing cartilage loss

ANTI-VIRAL COMPOSITIONS CONTAINING PIKFYVE INHIBITORS AND USE THEREOF

Method for inhibiting the expression of cancer-promoting factors

Methods and compositions for RNA-directed target DNA modification and for RNA-directed modulation of transcription

Methods and compositions for RNA-directed target DNA modification and for RNA-directed modulation of transcription

Methods and compositions for RNA-directed target DNA modification and for RNA-directed modulation of transcription

Anti-cancer RNA aptamers

FMRP and cancer treatment

HSD17B13 variants and uses thereof

Modified EC7 cells having low toxicity to viral production payloads

Prevention and/or treatment of hearing loss or impairment

Novel method of treating dystonia

TRANSGENIC PLANT OF THE SPECIES SOLANUM TUBEROSUM WITH RESISTANCE TO PHYTOPHTHORA

Compositions and methods for rapid and dynamic flux control using synthetic metabolic valves

COMBINATION GENE TARGETS FOR IMPROVED IMMUNOTHERAPY

Medical devices for delivery of siRNA

Method for treating or preventing heart failure

Serum amyloid P component (APCS) iRNA compositions and methods of use thereof

Use of specific siRNA against protein S for the treatment of hemophilia

Liposomes for modulating Wiskott-Aldrich syndrome protein

Use of leucine-zipper protein for diagnosis or treatment of fatty liver

COMPLEMENT COMPONENT iRNA COMPOSITIONS AND METHODS OF USE THEREOF

Medicine for treating cancer and method for treating cancer

Treatment of HIV

RNAi induced huntingtin gene suppression

RNAi CONJUGATES, PARTICLES AND FORMULATIONS THEREOF

Multivalent oligonucleotide assemblies

Bioactive conjugates for oligonucleotide delivery

NUCLEIC ACID MOLECULES ENCODING AN ENGINEERED ANTIGEN RECEPTOR AND AN INHIBITORY NUCLEIC ACID MOLECULE AND METHODS OF USE THEREOF

Compositions and methods useful in promoting milk production

Conjugates and preparation and use thereof

Method of treating a localized fibrotic disorder using an IL-33 antagonist

Reducing beta-catenin and IDO expression to potentiate immunotherapy

MULTI-TARGET MODULATION FOR TREATING FIBROSIS AND INFLAMMATORY CONDITIONS

RNA interference mediated inhibition of prolyl hydroxylase domain 2 (PHD2) gene expression using short interfering nucleic acid (SINA)

Dual Targeting siRNA Agents

Amphoteric liposomes comprising imino lipids

Ophthalmic delivery device and ophthalmic drug compositions

PARP9 and PARP14 as key regulators of macrophage activation

Methods and compositions for modulating gene expression using oligonucleotide based drugs administered in vivo or in vitro

Engineered producer cell lines and methods of making and using the same

Compositions and Methods for Inhibiting Expression of the PCSK9 Gene

Methods and compositions for the specific inhibition of KRAS by asymmetric double-stranded RNA

Influenza-activated constructs and methods of use thereof

RNAI AGENTS, COMPOSITIONS AND METHODS OF USE THEREOF FOR TREATING TRANSTHYRETIN (TTR) ASSOCIATED DISEASES

Reducing fratricide of immune cells expressing NKG2D-based receptors

Compositions and methods for inhibition of HAO1 (hydroxyacid oxidase 1 (glycolate oxidase)) gene expression

Compositions and methods for inhibiting PTPN22

Dynamin 2 inhibitor for the treatment of centronuclear myopathies

HIGH MOBILITY GROUP BOX-1 (HMGB1) IRNA COMPOSITIONS AND METHODS OF USE THEREOF

Composition for delivery of genetic material

TARGETING GLIOBLASTOMA STEM CELLS THROUGH THE TLX-TET3 AXIS

Oligonucleotide compounds for targeting huntingtin mRNA

KCNK3-BASED GENE THERAPY OF CARDIAC ARRHYTHMIA

RNA duplexes with single stranded phosphorothioate nucleotide regions for additional functionality

Trialkyl cationic lipids and methods of use thereof

Methods of treating bone loss

ApoCIII and the Treatment and Diagnosis of Diabetes

NTRK1 fusion molecules and uses thereof

Methods and compositions for RNA-directed target DNA modification and for RNA-directed modulation of transcription

Methods and compositions for RNA-directed target DNA modification and for RNA-directed modulation of transcription

NUCLEIC ACID MOLECULES THAT CONFER RESISTANCE TO COLEOPTERAN PESTS

Xanthine dehydrogenase (XDH) IRNA compositions and methods of use thereof

Dual activity super toxic RNAi active dsRNAs

Gene silencing kills emerald ash borer, an exotic, invasive tree-killing insect

Components and methods for producing toxic RNAs in eukaryotic cells

RNAi agents for inhibiting expression of alpha-ENaC and methods of use

RNAi agents and compositions for inhibiting expression of apolipoprotein C-III (APOC3)

Compositions and methods for rapid and dynamic flux control using synthetic metabolic valves

Fungal immunogens and related materials and methods

Treatment of increased lipid levels with sterol regulatory element binding protein cleavage-activating protein (SCAP) inhibitors

Treatment of increased lipid levels with sterol regulatory element binding transcription factor 1 (SREBF1) inhibitors

TREATMENT OF GLIAL CELL DERIVED NEUROTROPHIC FACTOR (GDNF) RELATED DISEASES BY INHIBITION OF NATURAL ANTISENSE TRANSCRIPT TO GDNF

PREVENTIVE OR THERAPEUTIC AGENT FOR FIBROSIS

HEPATITIS D VIRUS (HDV) iRNA COMPOSITIONS AND METHODS OF USE THEREOF

Methods and compositions for diagnosing and treating diseases

METHODS OF TREATING CANCER USING TIGIT INHIBITORS AND ANTI-CANCER AGENTS

Compositions for treating heart disease by inhibiting the action of mAKAPβ

Delivery method of target material into extracellular vesicles using extracorporeal shockwave

Exosomal loading using hydrophobically modified oligonucleotides

Nucleotide sequence and application thereof in enhancing plant pest resistance

RNAi agents and compositions for inhibiting expression of Asialoglycoprotein receptor 1

METHODS AND COMPOSITIONS TO TREAT DRUG-INDUCED DISEASES AND CONDITIONS

as a diagnostic and therapeutic target for NAFLD, NASH, metabolic syndrome, and hepatic fibrosis

Compositions and Methods for Inhibiting Expression of Transthyretin

BIOTIN COMPLEXES FOR TREATMENT AND DIAGNOSIS OF ALZHEIMER'S DISEASE

NOVEL CATIONIC LIPIDS AND METHODS OF USE THEREOF

Combination therapy for C3 inhibition

METHODS AND COMPOSITIONS FOR CELL-PROLIFERATION-RELATED DISORDERS

Compositions and methods for inhibiting expression of RRM2 genes

RNAi-MEDIATED INHIBITION OF HIF1A FOR TREATMENT OF OCULAR ANGIOGENESIS

Methods and compositions to inhibit metastasis and to treat fibrosis and to enhance wound healing

Insulin-like growth factor binding protein, acid labile subunit (IGFALS) and insulin-like growth factor 1 (IGF-1) iRNA compositions and methods of use thereof

Treatments of oxidative stress conditions

Compositions and methods for treatment of sepsis-related disorders

2'-METHOXY SUBSTITUTED OLIGOMERIC COMPOUNDS AND COMPOSITIONS FOR USE IN GENE MODULATIONS

PREDICTING AGE-RELATED MACULAR DEGENERATION WITH SINGLE NUCLEOTIDE POLYMORPHISMS WITHIN OR NEAR THE GENES FOR COMPLEMENT COMPONENT C2, FACTOR B, PLEKHA1, HTRA1, PRELP, OR LOC387715

siRNA compositions that specifically down regulate expression of a variant of the PNPLA3 gene and methods of use thereof for treating a chronic liver disease

Single-Stranded RNAI Oligonucleotides Targeting APOC-III

Methods and compositions for selecting siRNA of improved functionality

Dynamic pharmacokinetic-modifying anchors

ACTIVITY-DEPENDENT GENE PAIRS AS THERAPEUTIC TARGETS AND METHODS AND DEVICES TO IDENTIFY THE SAME

Complement component iRNA compositions and methods of use thereof

COMPOSITIONS AND METHODS FOR INHIBITING GENE EXPRESSION OF LPA

Compositions and Methods for Inhibition of Expression of Apolipoprotein C-III (APOC3) Genes

Treatment of hepatotoxicity with IL-11 antibody

Selenium Cancer Therapy

COMPOSITIONS AND METHODS FOR REGULATION OF GENE EXPRESSION WITH, AND DETECTION OF, FOLINIC ACID AND FOLATES

Oligonucleotide sequences targeting transcription factor TSC22D4 for the treatment of insulin resistance

Therapeutic compositions

miRNA biogenesis in exosomes for diagnosis and therapy

METHODS AND COMPOSITIONS FOR ALTERING FUNCTION AND STRUCTURE OF CHROMATIN LOOPS AND/OR DOMAINS

Stabilized HNF4A saRNA compositions and methods of use

HNF4A saRNA compositions and methods of use

BIOLOGICAL MATERIALS AND THERAPEUTIC USES THEREOF

Facile assembly of soft nanoarchitectures and co-loading of hydrophilic and hydrophobic molecules via flash nanoprecipitation

Methods and compositions using RNA interference and antisense oligonucleotides for inhibition of KRAS

Human antibodies to the human glucagon receptor and methods of use thereof to lower blood glucose or ketone levels

TARGETING GDF6 AND BMP SIGNALING FOR ANTI-MELANOMA THERAPY

METHODS OF TREATING MOTOR NEURON DISEASES

METHODS FOR DIAGNOSING AND TREATING PROSTATE CANCER

MULTI-CONJUGATE OF SIRNA AND PREPARING METHOD THEREOF

Control of plant pests using RNA molecules

Compositions and methods for inhibition of expression of protein C (PROC) genes

Lipid formulated compositions and methods for inhibiting expression of serum amyloid A gene

Delivery of hydrophobic active agent particles

USE OF RNAI INHIBITING PARP ACTIVITY FOR THE MANUFACTURE OF A MEDICAMENT FOR THE TREATMENT OF CANCER

Method and composition for targeted delivery of therapeutic agents

Control of hemipteran pests using RNA molecules

COMPOSITIONS AND METHODS TO CONTROL INSECT PESTS

Quality protein maize based on increased sulfur reduction in leaf cells

Anticancer therapeutic intervention

Nucleic acid simultaneously inhibiting expression of AR gene and mTOR gene

COMPOSITIONS AND METHODS FOR INHIBITING EXPRESSION OF FACTOR V

Double-stranded RNA molecule targeting CKIP-1 and use thereof

Agents useful in treating facioscapulohumeral muscular dystrophy

Treatment of ophthalmic conditions with angiopoietin-like 7 (ANGPTL7) inhibitors

Gene therapies for lysosomal disorders

Compositions and methods comprising histidyl-tRNA synthetase splice variants having non-canonical biological activities

Use of Circ-CDH1 inhibitors

SCREENING METHOD FOR SELECTED AMINO-LIPID-CONTAINING COMPOSITIONS

HOMEOBOX TRANSCRIPTION FACTOR VENTX REGULATES DIFFERENTIATION AND MATURATION OF HUMAN DENDRITIC CELLS

Angiopoietin-like 3 (ANGPTL3) iRNA compositions and methods of use thereof

MODULATION OF IMMUNE RESPONSE THROUGH STIMULATOR OF INTERFERON GENES

METHODS OF MODULATING FAM46A

Therapeutic targeting of SET1B/compass pathway for treating cancers

Biodegradable lipids for delivery of nucleic acids

Hybridosomes, compositions comprising the same, processes for their production and uses thereof

Variant RNAi

SERPINC1 iRNA COMPOSITIONS AND METHODS OF USE THEREOF

CONDITIONAL PROTEIN TRANSLATION SWITCHES, CONDITIONAL GENE EXPRESSION SYSTEMS AND USES THEREOF

Compositions and methods comprising histidyl-tRNA synthetase splice variants having non-canonical biological activities

Targeting synaptogyrin-3 in tauopathy treatment

CHEMICALLY MODIFIED OLIGONUCLEOTIDES

Methods and compositions for improving exercise endurance, performance, or tolerance

Microbubble nucleic acid delivery platform

Plants with shortened time to flowering

Inhibition of SEMA3A in the prevention and treatment of ocular hyperpermeability

RNA LIGAND-DISPLAYING EXOSOMES FOR SPECIFIC DELIVERY OF THERAPEUTICS TO CELL BY RNA NANOTECHNOLOGY

ALLELE SELECTIVE INHIBITION OF MUTANT C9ORF72 FOCI EXPRESSION BY DUPLEX RNAS TARGETING THE EXPANDED HEXANUCLEOTIDE REPEAT

Long noncoding RNAs in pulmonary airway inflammation

METHODS FOR TREATING OR PREVENTING CONTACT-ACTIVATION PATHWAY-ASSOCIATED DISEASES USING iRNA COMPOSITIONS TARGETING FACTOR XII (HAGEMAN FACTOR) (F12)

Alpha-1 antitrypsin (AAT) RNAi agents, compositions including AAT RNAi agents, and methods of use

Platelets as delivery agents

METHODS FOR MODULATING THE INTERACTION BETWEEN EWS-FLI1 AND BAF COMPLEXES

INSTANT THICKENED DRY FOOD COMPOSITIONS

Modulatory polynucleotides

RNA interference mediated inhibition of hepatitis B virus (HBV) gene expression using short interfering nucleic acid (SINA)

tRNA derived small RNAs (tsRNAs) involved in cell viability

siRNA Therapy for Transthyretin (TTR) Related Ocular Amyloidosis

Apolipoprotein C3 (APOC3) iRNA compositions and methods of use thereof

IDENTIFICATION OF VSIG8 AS THE PUTATIVE VISTA RECEPTOR (V-R) AND USE THEREOF TO PRODUCE VISTA/VSIG8 AGONISTS AND ANTAGONISTS

GENETICALLY MANIPULATED CORNEA FOR TRANSPLANTATION

CD25 PRE-SELECTIVE COMBINATION ANTI-HIV VECTORS, TARGETING VECTORS, AND METHODS OF USE

Nucleic acid-loaded unit polyion complex

DRUG CARRIER AND DRUG DELIVERY SYSTEM THEREOF

Methods and compositions for RNA-directed target DNA modification and for RNA-directed modulation of transcription

METHODS FOR REDUCING DNA-INDUCED CYTOTOXICITY AND ENHANCING GENE EDITING IN PRIMARY CELLS

PKLR inhibition in the treatment of NAFLD and HCC

COMPOUNDS AND METHODS FOR MODULATING TMPRSS6 EXPRESSION

METHOD OF TREATING KELOIDS OR HYPERTROPHIC SCARS USING ANTISENSE COMPOUNDS TARGETING CONNECTIVE TISSUE GROWTH FACTOR (CTGF)

Peptide, complex of peptide and siRNA, and methods of use thereof

Organic compositions to treat EPAS1-related diseases

Oligonucleotide compositions and methods of use thereof