Method for assessing the efficacy of IMiDs and composition or combination for use in treating IMiD sensitive diseases

PLASMIDS COMPRISING INTERNAL RIBOSOMAL ENTRY SITES AND USES THEREOF

Method for selectively inhibiting ACAT1 in the treatment of neurodegenerative diseases

HER3 Inhibition in Low-grade Serous Ovarian Cancers

ANTI-INFLUENZA VIRUS AGENT AND SCREENING METHOD FOR ANTI-INFLUENZA VIRUS AGENT

FSH nucleic acid molecules to control insect pests

Polypeptides having beta-xylosidase activity and polynucleotides encoding same

BIOLOGICAL CONTROLS OF COLEOPTERAN PESTS

Compositions and methods for diagnosis and treatment of prostate cancer

KRAS nucleic acids and uses thereof

RNA interference compositions targeting heat shock protein 90 and methods of use thereof

DESIGN OF NUCLEIC ACID BINDING MOLECULES WITH NON-WATSON CRICK AND NON-CANONICAL PAIRING BASED ON ARTIFICIAL MUTATION CONSENSUS SEQUENCES TO COUNTER ESCAPE MUTATIONS

Therapeutic compositions

Blocking monoclonal antibodies to AGR2 and its receptor C4.4A

Compositions and methods for treating and preventing inflammation

Programmable polypeptide and nucleic acid nanoparticles

NUCLEIC ACID-POLYPEPTIDE COMPOSITIONS AND USES THEREOF

Molecular targets for the treatment of wounds, in particular chronic wounds

Methods and compositions for the treatment of cancer

Chimeric single-stranded antisense polynucleotides and double-stranded antisense agent

Modified double-stranded RNA agents

Cancer treatment and immune system regulation through FAT10 pathway inhibition

Chiral control

Compositions and methods for treating vascular disorders

METHODS AND COMPOSITIONS FOR THE SPECIFIC INHIBITION OF MYC BY DOUBLE-STRANDED RNA

Methods of preserving and protecting pancreatic beta cells and treating or preventing diabetes by inhibiting NOX-1

Triggering RNA interference with RNA-DNA and DNA-RNA nanoparticles

Methods for identifying and treating invasive/metastatic breast cancers

Method and treatment of recurring endometrial cancer with an inhibitor of USP14

Methods and compositions for preventing or reducing infections of crop plants by bacterial and fungal pathogens

DIAGNOSTIC AND THERAPEUTIC TARGETING OF DNMT-1 ASSOCIATED RNA IN HUMAN CANCER

COMPLEMENT COMPONENT C5 iRNA COMPOSITIONS AND METHODS OF USE THEREOF

Oligomeric compounds and compositions for use in modulation of small non-coding RNAs

Approach for treatment of cancer via immunomodulation by using talabostat

Compositions for modulating cancer stem cells and uses therefor

Methods for sub-typing and treating cancer

Next generation RNA-sequencing and long non-coding RNA in glioblastoma multiforme

MUCOSAL HEALING PROMOTER

Repressor on IFN-λ promoter and siRNA against GATA1, EVI1, and CRX to alter IFN-λ gene activity

POLYNUCLEOTIDES AND POLYPEPTIDE SEQUENCES INVOLVED IN THE PROCESS OF BONE REMODELING

Delivery of dsRNA to arthropods

Apolipoprotein C3 (APOC3) iRNA compositions and methods of use thereof

Methods of treating, inhibiting and/or preventing an auditory impairment

NON-LIPOSOMAL SYSTEMS FOR NUCLEIC ACID DELIVERY

Compositions and methods for controlling insect pests

Exosome transfer of nucleic acids to cells

Bacterially derived intact minicells that encompass plasmid free DNA and methods of using the same

Method for determining the repair activity of non-homologous end joining

COMPOSITIONS AND METHODS TO CONTROL INSECT PESTS

Target of VGSC β3 protein for prevention, treatment and diagnostic detection of cancers

COMPOSITIONS AND METHODS OF SELECTIVELY INHIBITING IRP1 AND TREATING INFLAMMATION

APTAMER-RNAi THERAPEUTIC COMPOSITIONS

Targeting ligands for therapeutic compounds

COMPLEMENT COMPONENT C5 IRNA COMPOSITIONS AND METHODS OF USE THEREOF

Polypeptide inhibitors of Smad3 polypeptide activities

NUCLEIC ACID CONSTRUCTS INCLUDING A TXNIP PROMOTER FOR THE TREATMENT OF DISEASE

Method of predicting obesity comprising measuring neurotensin

ANTI-CANCER AGENT SENSITIVITY-DETERMINING MARKER

Methods and compositions for root knot nematode control

Interfering RNA molecules

CDC25A inhibitor for the treatment of drug resistant cancer or for the prevention of tumor relapse

NUCLEIC ACID CAPABLE OF INHIBITING EXPRESSION OF BETA-2GPI

NUCLEIC ACID CAPABLE OF INHIBITING EXPRESSION OF BETA-2GPI

Interfering RNA molecules

Interfering RNA molecules

MICRORNA WITH PLACENTA-PERMEABILITY AND USES THEREOF

COMPOSITIONS AND METHODS FOR TREATING NEUROLOGICAL DISORDERS

Interfering RNA molecules

Polyol-based osmotic polydixylitol polymer gene transporter and use thereof

MAP3K8 AS A MARKER FOR SELECTING A PATIENT AFFECTED WITH AN OVARIAN CANCER FOR A TREATMENT WITH A MEK INHIBITOR

PREDICTING AMD WITH SNPS WITHIN OR NEAR C2, FACTOR B, PLEKHA1, HTRA1, PRELP, OR LOC387715

Methods and Materials for Producing Coreless Fruit

IMPAIRED WOUND HEALING COMPOSITION AND TREATMENTS

Modulation of breast cancer growth by modulation of XBP1 activity

Method and composition for the treatment, prevention, and diagnosis of cancer containing or derived from cancer stem cells

NUCLEIC ACIDS, AND USES THEROF

Multiplexed shRNAs and uses thereof

GNAQ targeted dsRNA compositions and methods for inhibiting expression

DNA-RNA hybrid particles and manufacturing method thereof

VITAMIN K EPOXIDE RECYCLING POLYPEPTIDE VKORC1, A THERAPEUTIC TARGET OF COUMARIN AND THEIR DERIVATIVES

Compositions and methods for enhancing cardiac function in the neonate

Antibody-siRNA conjugates and uses therefor

Small molecule inhibitors of RNA binding motif (RBM) proteins for the treatment of acute cellular injury

BIOLOGICALLY ACTIVE NUCLEOTIDE MOLECULES FOR SELECTIVELY KILLING OFF CELLS, USE THEREOF, AND APPLICATION KIT

UREIDOPYRIMIDONE SUPRAMOLECULAR COMPLEXES FOR COMPOUND DELIVERY INTO CELLS

Compositions for controlling mites in bees

Compositions Comprising Small Interfering RNA Molecules for Prevention and Treatment of Ebola Virus Disease

Allele selective inhibition of mutant C9orf72 foci expression by duplex RNAS targeting the expanded hexanucleotide repeat

NUCLEIC ACID LIPID PARTICLE FORMULATIONS

Twist signaling inhibitor compositions and methods of using the same

Tetragalnac containing conjugates and methods for delivery of oligonucleotides

POROUS NANOPARTICLE-SUPPORTED LIPID BILAYERS (PROTOCELLS) FOR TARGETED DELIVERY INCLUDING TRANSDERMAL DELIVERY OF CARGO AND METHODS THEREOF

Breast Tumor Markers And Methods Of Use Thereof

DETECTION OF VIRAL INFECTION

INHIBITORY RNA FOR ENHANCED PROTEIN PRODUCTION IN RECOMBINANT MAMMALIAN CELLS

PME-1 as a biomarker to predict and diagnose an increased risk of endometrial cancer and gene silencing of PME-1 to inhibit epithelial to mesenchymal transition

METHODS OF TREATING ISCHEMIA-REPERFUSION INJURY WITH siRNAS

TREATMENT OF GLIAL CELL DERIVED NEUROTROPHIC FACTOR (GDNF) RELATED DISEASES BY INHIBITION OF NATURAL ANTISENSE TRANSCRIPT TO GDNF

PREVENTION OF TUMOUR METASTASIS BY INHIBITION OF NECROPTOSIS

Nucleic acid aptamers

Method for improving memory using CCNY inhibitor

Cationic lipid

Screening method

PANCREATIC CANCER TARGETS AND USES THEREOF

GAWKY (GW) NUCLEIC ACID MOLECULES TO CONTROL INSECT PESTS

RPB7 NUCLEIC ACID MOLECULES TO CONTROL INSECT PESTS

Methods for preparing pecific polypeptide-binding antibodies

Treatment of atopic dermatitis and asthma using RNA complexes that target IL4Rα, TRPA1, or F2RL1

Treatment of angiogenesis-associated diseases using RNA complexes that target ANGPT2 and PDGFB

Composition for diagnosis of liver metastasis of colorectal cancer and the use thereof

METHODS FOR MALIGNANT TUMORS WITH RNAI MOLECULES TARGETED TO HSP47

OLIGONUCLEOTIDES FOR MODULATING TARGET RNA ACTIVITY

DELIVERY MOLECULES FOR THERAPEUTICS

Methods and compositions for perturbing gene expression in hematopoietic stem cell lineages in vivo

Administration of FGF9 for treatment and prevention of major depression

Methods and compositions for inhibiting growth and epithelial to mesenchymal transition (EMT) in cancer cells

Treatment of brain derived neurotrophic factor (BDNF) related diseases by inhibition of natural antisense transcript to BDNF

Prophylactic agent and therapeutic agent for fibrodysplasia ossificans progressiva

ENHANCED REPROGRAMMING TO IPS CELLS

Honey bee mite disruptive compounds and methods of application

BARD1 isoforms in lung and colorectal cancer and use thereof

USE OF H2A.Z.1 AS A HEPATOCELLULAR CARCINOMA BIOMARKER

METHODS FOR OPTIMIZING ELECTROPORATION

MrgprX2/MrgprB2 expressing cell based assay to detect pseudo-allergic drug reactions and to identify blockers to prevent the adverse reactions

dsRNA for treating viral infection

Methods and compositions for treating insects

Compositions for Targeted Delivery of siRNA

Method for secretion of extracellular vesicles from cells and tissues using shock wave

Inhibition of serotonin expression in gut enteroendocrine cells results in conversion to insulin-positive cells

SYNTHESIS AND USE OF AMINO LIPIDS

Aminoalcohol lipidoids and uses thereof

Methods of inhibiting cancer stem cells with HMGA1 inhibitors

R2R1/2 in diagnosis and therapy

ENGINEERING MAMMALIAN GENOME USING DNA-GUIDED ARGONAUTE INTERFERENCE SYSTEMS (DAIS)

Nurr1 as a genetic target for treating levodopa-induced dyskinesias in Parkinson's disease

RNAi-MEDIATED INHIBITION OF HIF1A FOR TREATMENT OF OCULAR ANGIOGENESIS

Preventive or therapeutic agent for fibrosis

Methods and Compositions for Modulating Lung Cancer Tumor Initiating Cells (TIC), and Oxytocin Receptor (OXTR) Modulatory Agents for Use in Practicing the Same

COMPOSITION FOR TREATING CANCER ASSOCIATED WITH HPV INFECTION

Diagnostic and therapeutic tool for cancer

Compositions And Methods For Treating Tumors And Immune Based Inflammatory Diseases

Cationic lipid

Lung cancer adjuvant therapy

Method of encapsulating a nucleic acid in a lipid nanoparticle host

Biomarkers for human monocyte myeloid-derived suppresor cells

Decreasing lactate level and increasing polypeptide production by downregulating the expression of lactate dehydrogenase and pyruvate dehydrogenase kinase

Solid Phase Transfection of Proteins and Nucleic Acids

COMPOSITIONS AND METHODS OF USING SAME FOR INCREASING RESISTANCE OF INFECTED MOSQUITOES

Targeting the steroidogenic pathway for treating and/or preventing allergic diseases

PERFORIN 2 DEFENSE AGAINST INVASIVE AND MULTIDRUG RESISTANT PATHOGENS

RNA EDITING BIOMARKERS FOR DIAGNOSIS, PHARMACOLOGICAL SCREENING AND PROGNOSTICATION IN CANCER

Angiotensinogen (AGT) iRNA compositions and methods of use thereof

USE OF PHOSPHORYLATION PATHWAY-RELATED FACTOR IN REGULATING FUNCTION OF REGULATORY T CELL

Bruton's tyrosine kinase as anti-cancer drug target

Exosomal loading using hydrophobically modified oligonucleotides

Compositions and methods for controlling insect pests

Methods and compositions for treating neuropathic pain

Polynucleotide agents targeting complement component C5 and methods of use thereof

Use of miR-199a-5p, targets and/or inhibitors thereof for the diagnosis, prognosis and treatment of fibroproliferative disorders

Method of separating senescent cells using overexpression of protocadherin

Composition including pint gene expression inhibitor or pint activity inhibitor and use thereof

LNCRNAS FOR THERAPY AND DIAGNOSIS OF CARDIAC HYPERTROPHY

Composition for delivery of genetic material

METHODS OF TREATING MITOCHONDRIAL DYSFUNCTION

Retroviral vector having immune-stimulating activity

COMPOSITIONS AND METHODS FOR THE SUPPRESSION OF TARGET POLYNUCLEOTIDES FROM LEPIDOPTERA

Ribosomal protein L40 (RPL40) nucleic acid molecules that confer resistance to coleopteran and hemipteran pests

Methods of treating cancer

Exon skipping technology in VCP disease

Inhibition of Bruton's tyrosine kinase (Btk) in the lung to treat severe lung inflammation and lung injury

INDIVIDUALIZED CANCER THERAPY

Methods of controlling cell fate and consequences for disease

Lepidopteran moth control using double-stranded RNA constructs

Composition and method of using miR-302 precursors as anti-cancer drugs for treating human lung cancer

Method for treating fibrosis using siRNA and a retinoid-lipid drug carrier

Methods for modulating Ataxin 2 expression

Skin Permeating and Cell Entering (SPACE) Peptides and Methods of Use Thereof

Drug delivery particle and method for producing the same

LONG NON-CODING RNA AS A DIAGNOSTIC AND THERAPEUTIC AGENT

METHOD FOR OPENING TIGHT JUNCTIONS

siRNA structures for high activity and reduced off target

COMPOSITIONS AND METHODS FOR TARGETING O-LINKED N-ACETYLGLUCOSAMINE TRANSFERASE AND PROMOTING WOUND HEALING

Treatment of Liver Cancer through Embolization Depot Delivery of BORIS Gene Silencing Agents

Methods and compositions for RNA-directed target DNA modification and for RNA-directed modulation of transcription

Methods for the treatment of cardiovascular fibrosis

METHODS OF TREATING A METABOLIC SYNDROME BY MODULATING HEAT SHOCK PROTEIN (HSP) 90-BETA

Methods and compositions for treating malignant tumors associated with kras mutation

COMPOSITION OF LIPID-BASED NANOPARTICLES FOR SMALL MOLECULES AND MACROMOLECULES

COMPOSITIONS AND METHODS FOR MODULATION OF RORGAMMAT FUNCTIONS

Methods and compositions for the specific inhibition of gene expression by double-stranded RNA

Methods and compositions for treating a Serpinc1-associated disorder

Small interfering RNA and pharmaceutical composition and method for inhibiting galectin-12 expression and/or enhancing lipolysis containing the same

Medical devices for delivery of siRNA

Modified natural killer cells and natural killer cell lines having increased cytotoxicity

Methods of treating fragile X syndrome and related disorders

Composition, kit, and method for diagnosing and treating ovarian cancer

Method of producing lipid nanoparticles for drug delivery

Methods for triggering de novo formation of heterochromatin and or epigenetic silencing with small RNAS

Modulation of BCL11A for treatment of hemoglobinopathies

Nanoparticle type oligonucleotide structure having high efficiency and method for preparing same

LIPID PARTICLES WITH CATIONIC LIPIDS FOR RNA DELIVERY

Cell lines for virus production and methods of use

Ship inhibition to induce activation of natural killer cells

METHODS FOR THE TREATMENT OF INFECTIONS AND TUMORS

Use of compounds inhibiting apelin / APJ / GP130 signaling for treating cancer

Multicistronic expression constructs

Modular construction of synthetic gene circuits in mammalian cells using TALE transcriptional repressors

Use of Mcoln-1 modulators to regulate cell migration

Double stranded RNA constructs for aphid control

METHODS AND COMPOSITIONS FOR THE TREATMENT OF CANCER

Combination of Anti-Clusterin Oligonucleotide with HSP90 Inhibitor for the Treatment of Prostate Cancer

Transferrin/transferrin receptor-mediated siRNA delivery

Treatment of Frataxin (FXN) related diseases by inhibition of natural antisense transcript to FXN

Treatment of nuclear factor (erythroid-derived 2)-like 2 (NRF2) related diseases by inhibition of natural antisense transcript to NRF2

Ionizable cationic lipid for RNA delivery

METHODS OF TREATING CANCER USING TIGIT INHIBITORS AND ANTI-CANCER AGENTS

Pharmaceutical composition for preventing or treating neurodegenerative diseases

Cell-targeting nanoparticles comprising polynucleotide agents and uses thereof

NANOCOMPOSITES OF GOLD AND POLYMERS

LIPID FORMULATION

Double strand RNA-mediated RNA interference through feeding detrimental to larval (gypsy moth)

Treatment of age-related macular degeneration using RNA complexes that target MYD88 or TLR3

Compositions and methods for inhibiting expression of RRM2 genes

Apoptosis inducer

NEW TREATMENT AGAINST INFLUENZA VIRUS

Inhibition of PCSK9 through RNAI

MOLECULES AND AGENTS FOR TREATING HEPATITIS B VIRUS

NOVEL SINGLE CHEMICAL ENTITIES AND METHODS FOR DELIVERY OF OLIGONUCLEOTIDES

Organic compositions to treat APOC3-related diseases

Nucleic acid functionalized nanoparticles for therapeutic applications

IMPROVED SMALL INTERFERING RIBONUCLEIC ACID MOLECULES

Amine cationic lipids and uses thereof

Pharmaceutical composition and uses thereof

Inhibition of chemokine CCL7 or receptor CCR3 of same for the treatment and diagnosis of prostate cancer

METHODS, ASSAYS, AND SYSTEMS RELATING TO SAKT

Trans-acting elements for intracellular delivery of nucleic acid sequences

SHIBIRE/DYNAMIN NUCLEIC ACID MOLECULES TO CONTROL COLEOPTERAN AND HEMIPTERAN PESTS

Methods for immortalization of epithelial cells

Double-stranded oligo RNA targeted to amphiregulin and pharmaceutical composition comprising same for preventing or treating fibrosis or respiratory diseases

Methods of using PVT1 exon 9 to diagnose and treat prostate cancer

Compositions and methods to activate or inhibit toll-like receptor signaling

Modified oligonucleotides for telomerase inhibition

Replication factor C-40 (RFC40/RFC2) as a prognostic marker and target in estrogen positive and negative and triple negative breast cancer

Small molecules that enhance the activity of oligonucleotides

Methods and compositions for the specific inhibition of alpha-1 antitrypsin by double-stranded RNA

Human antibodies to the glucagon receptor and methods of use thereof for lowering blood glucose or ketone levels

METHOD FOR PREPARING RECOMBINANT GLYCOPROTEIN HAVING HIGH SIALIC ACID CONTENT, THROUGH GLYCOSPHINGOLIPID SYNTHESIS CYCLE CONTROL

Peptide sequence design and use thereof for peptide-mediated siRNA delivery

SHIP INHIBITION TO INDUCE EXPRESSION OF GRANULOCYTE COLONY STIMULATING FACTOR IN A SUBJECT

Liposomal formulations for delivery of nucleic acids

Algal mutants with increased lipid productivity

METHOD FOR PRODUCING LIPID PARTICLES AND NUCLEIC ACID DELIVERY CARRIER HAVING LIPID PARTICLES

NUCLEIC ACID-CONTAINING LIPID PARTICLES AND RELATED METHODS

Multifunctional RNA nanoparticles and methods of use

Compositions and methods for rapid and dynamic flux control using synthetic metabolic valves

Inhibitors of metastasis

Peptide, complex of peptide and siRNA and use thereof

Lipid particles and nucleic acid delivery carrier

Method for treating kidney disease with a SLIT2-binding extracellular domain of ROBO2

Method for expression of small RNA molecules within a cell

Reduction of TGFβ signaling in myeloid cells in the treatment of cancer

Serpina1 iRNA compositions and methods of use thereof

POLYNUCLEOTIDE CONSTRUCTS HAVING BIOREVERSIBLE AND NON-BIOREVERSIBLE GROUPS

RAAV-based compositions and methods for treating amyotrophic lateral sclerosis

Use of negative functional modulators of erythropoietin for therapy

SLIT-ROBO-Myo9-RHOA PATHWAY AND CANCER

Ionizable cationic lipid for RNA delivery

Delivery of hydrophobic active agent particles

VISTA MODULATORS FOR DIAGNOSIS AND TREATMENT OF CANCER

CELL DELIVERY SYSTEM AND METHOD

All sterile males of culicine mosquitoes: a method of creation

COMPOSITIONS, METHODS AND KITS FOR CHARACTERIZING AND SCREENING FOR SMALL CELL OVARIAN CARCINOMA

Pharmaceutical composition for treating chronic kidney disease

Method for expression of small antiviral RNA molecules with reduced cytotoxicity within a cell

Monomers and oligonucleotides comprising cycloaddition adduct(s)

Oligonucleotide end caps

Methods of cancer therapy by inhibiting fusion polypeptides comprising fibroblast growth factor receptor 2 (FGFR2) and vinculin (VCL)

Transmission blocking vaccines for mosquito-borne

STAT5a and its functional tumor suppressor analogs for treatment of malignancies expressing NPM/ALK and other oncogenic kinases

Methods For Treating Nicotinic Acetylcholine Receptor Associated Diseases

Small interfering RNA (siRNA) for the therapy of type 2 (ADO2) autosomal dominant osteopetrosis caused by CLCN7 (ADO2 CLCN7-dependent) gene mutation

METHODS OF INHIBITING VIRAL REPLICATION COMPRISING THE SIGNAL PEPTIDASE COMPLEX

Modulation of gene expression and screening for deregulated protein expression

Modulation of human cytomegalovirus replication by micro-RNA 132 (miR132), micro-RNA 145 (miR145) and micro-RNA 212 (miR212)

RNAi PHARMACEUTICAL COMPOSITION FOR SUPPRESSING EXPRESSION OF CKAP5 GENE

Compounds and methods for trans-membrane delivery of molecules

Lipocationic polymers and uses thereof

Genomic instability markers in Fanconi anemia

Use of CPNE7 for differentiating non-dental mesenchymal stem cells into odontoblasts, regenerating dental pulp and treating dentin hypersensitivity

PHARMACEUTICAL COMPOSITIONS COMPRISING DANIRIXIN FOR TREATING INFECTIOUS DISEASES

INHIBITING GENE EXPRESSION WITH dsRNA

Compositions and methods for inhibiting gene expression of LPA

siRNA Therapy for Transthyretin (TTR) Related Ocular Amyloidosis

Diblock copolymers and polynucleotide complexes thereof for delivery into cells

AGENTS INHIBITING GRANULIN FOR TREATMENT OF CANCER

Neurotensin-induced tumor formation is regulated by micro RNA 133A-aftiphilin-dependent receptor recycling

Compositions and methods for controlling arthropod parasite and pest infestations

Antibody-Based Depletion of Antigen-Presenting Cells and Dendritic Cells

METHODS FOR TREATING AND PREVENTING ALLERGIES AND ACUTE ALLERGIC RESPONSES

Tumor associated vaccines and compositions for disrupting tumor-derived immunosuppression for use in combination cancer immunotherapy