109145 ⎘
Structure or type of the nucleic acid; Type of nucleic acid interfering N.A.
Methods for modulating KLHL1 levels, methods for modulating current activity in T-type calcium channels, molecules therefor, and methods for identifying molecules therefor
#4802Methods for improving cognitive function via modulation of quinone reductase 2
#4803Method of Modulating Fibroblast Accumulation or Collagen Deposition
#4804NUCLEIC ACID THAT INHIBITS EXPRESSION OF IRF5
#4805METHODS AND COMPOSITIONS FOR PREVENTING ISCHEMIA REPERFUSION INJURY IN ORGANS
#4806Retinoid-lipid drug carrier
#4807COMPOUNDS, COMPOSITION, METHODS, TARGETS FOR CANCER THERAPY
#4808Cell penetrating peptides for intracellular delivery of molecules
#4809Polypeptides having peroxygenase activity
#4810Polypeptides Having Peroxygenase Activity
#4811Peptide containing conjugates for dual molecular delivery of oligonucleotides
#4812Anti-PVRIG antibodies and methods of use
#4813Carrier nanoparticles and related compositions, methods and systems
#4814COMPOUNDS AND METHODS FOR TRANS-MEMBRANE DELIVERY OF MOLECULES
#4815Technology for the Preparation of Microparticles
#4816ANTAGONISTS OF SLC38A9 AND THEIR USE IN THERAPY
#4817MELK Regulation for the Treatment of Breast Cancer
#4818Cell-type specific aptamer-siRNA delivery system for HIV-1 therapy
#4819RNAi-Mediated Inhibition of Frizzled Related Protein-1 for Treatment of Glaucoma
#4820Treatment of Collagen gene related diseases by inhibition of natural antisense transcript to a collagen gene
#4821Compositions and Methods for Selective Delivery of Oligonucleotide Molecules to Cell Types
#4822Organic compositions to treat HSF1-related diseases
#4823Use of inhibitors of leukotriene B4 receptor BLT2 for treating asthma
#4824MiR-320e and colorectal cancer
#4825Invertebrate microRNAs
#4826Compositions and methods for inhibiting expression of CD274/PD-L1 gene
#4827SUGAR CHAIN-RELATED GENE AND USE THEREOF
#4828RNA interference in dermal and fibrotic indications
#4829Skin and hair color-controlling factor
#4830RNA-interference by single-stranded RNA molecules
#4831MicroRNAs 206 and 21 cooperate to promote RAS-extracellular signal-regulated kinase signaling by suppressing the translation of RASA1 and SPRED1
#4832Reprogramming of human wharton's jelly cells to produce hair cells
#4833Esophageal cancer marker and use thereof
#4834Metal-particle-based oral-administrating liver-specific nucleic acid delivery system and method of manufacturing the same
#4835Eukaryotic cells and methods for recombinantly expressing a product of interest
#4836SiRNAs and their use in methods and compositions for the treatment and/or prevention of eye conditions
#4837COMPOSITIONS AND METHODS OF USING SAME FOR CONTROLLING PATHOGENICALLY INFECTED MOSQUITOES
#4838METHODS FOR MODULATING IMMUNE RESPONSES DURING CHRONIC IMMUNE CONDITIONS BY TARGETING IL-27 INDUCED PATHWAYS
#4839Compositions and methods for transport across the blood brain barrier
#4840LOW DENSITY LIPOPROTEIN RECEPTOR-MEDIATED siRNA DELIVERY
#4841Methods of treating autoimmune conditions in patients with genetic variations in DcR3 or in a DcR3 network gene
#4842Methods and compositions for RNA-directed target DNA modification and for RNA-directed modulation of transcription
#4843RNAi-mediated inhibition of phosphodiesterase type 4 for treatment of CAMP-related ocular disorders
#4844METHODS FOR TREATMENT OF DISORDERS IN THE FRONT OF THE EYE UTILIZING NUCLEIC ACID MOLECULES
#4845Composition for enhancing radiation sensitivity comprising PI4K isozyme inhibitor
#4846Methods for treating cancer using nucleic acids targeting MDM2 or MYCN
#4847METHODS AND MODIFICATIONS THAT PRODUCE ssRNAi COMPOUNDS WITH ENHANCED ACTIVITY, POTENCY AND DURATION OF EFFECT
#4848COMPOSITIONS AND METHODS OF USING SAME FOR REDUCING RESISTANCE TO MOSQUITO LARVICIDES
#4849RNA interference for the treatment of gain-of-function disorders
#4850Method and composition for diagnosis or treatment of aggressive prostate cancer
#4851Compositions comprising a mitofusin inhibitor for promoting cell reprogramming and a use thereof
#4852Methods and Pharmaceutical Compositions for the Treatment of Diseases Mediated by the NRP-1/OBR Complex Signaling Pathway
#4853Therapeutic drug for malignant tumors
#4854P97-polynucleotide conjugates
#4855MULTIBLOCK COPOLYMERS
#4856Pharmaceutical combination comprising a CIP2A silencing agent for use in the treatment of a hyperproliferative disorder, preferably one with impaired P53 function
#4857Pdia4 protein as a target for diagnosis, monitoring and treatment of diabetes
#4858Targeting PARP1 for treatment of TSC and cancers
#4859Genetic alterations on chromosome 16 and methods of use thereof for the diagnosis and treatment of type 1 diabetes
#4860Recombinant RNA particles and methods of producing proteins
#4861Polycomb-associated non-coding RNAs
#4862SiRNA in tandem expression and uses thereof in treating chronic lymphocytic leukemia
#4863METHODS AND COMPOSITIONS FOR THE TREATMENT OF CANCER
#4864Compositions and methods to promote erythropoiesis
#4865SARNA COMPOSITIONS AND METHODS OF USE
#4866Methods for producing enteroendocrine cells that make and secrete insulin
#4867Transposon Activation During Aging and Neuronal Decline
#4868tRNA derived small RNAs (tsRNAs) involved in cell viability
#4869REDUCING CUTANEOUS SCAR FORMATION AND TREATING SKIN CONDITIONS
#4870Antibodies and processes for preparing the same
#4871Aptamer-mRNA conjugates for targeted protein or peptide expression and methods for their use
#4872Bioactive conjugates for oligonucleotide delivery
#4873Compositions and methods for modulating stem cells and uses thereof
#4874Compositions and methods for treating hepatitis B
#4875Methods targeting miR-128 for regulating cholesterol/lipid metabolism
#4876Methods for treating T-cell acute lymphoblastic leukemia
#4877USE OF CASEIN KINASE I INHIBITORS FOR DEPLETING STEM CELLS
#4878LIPID NANO PARTICLES COMPRISING CATIONIC LIPID FOR DRUG DELIVERY SYSTEM
#4879NANOPARTICLES FOR TARGETED GENE THERAPY AND METHODS OF USE THEREOF
#4880NOVEL LIPID FORMULATIONS FOR NUCLEIC ACID DELIVERY
#4881NEAT1 as a prognostic marker and therapeutic target for prostate cancer
#4882Compositions and methods for virus control in mite and bees
#4883Pharmaceutical composition comprising Nanog shRNA, and method of using Nanog shRNA to treat cancer
#4884LncRNAs for therapy and diagnosis of angiogenesis
#4885Oligomeric compounds and compositions for use in modulation of small non-coding RNAs
#4886COMPOUNDS AND METHODS FOR TRANS-MEMBRANE DELIVERY OF MOLECULES
#4887MODULATING IMMUNE RESPONSES
#4888Polypeptides having cellobiohydrolase activity and polynucleotides encoding same
#4889Targeted therapy to restore radioactive iodine transport in thyroid cancer
#4890Methods for treating and/or limiting development of diabetes
#4891Compositions and methods for controlling pests
#4892RNA interference mediated inhibition of catenin (cadherin-associated protein), beta 1 (CTNNB1) gene expression using short interfering nucleic acid (siNA)
#4893TRUNCATED TRK B AND TRK C ANTAGONISTS AND USES THEREOF
#4894Treatment using truncated Trk B and Trk C antagonists
#4895Methods for eliminating or reducing the expression of genes in filamentous fungal strains by transitive RNA interference
#4896Plant-protecting RNAi compositions comprising plant-protecting double-stranded RNA adsorbed onto layered double hydroxide particles
#4897RNA modulating oligonucleotides with improved characteristics for the treatment of duchenne and becker muscular dystrophy
#4898Transthyretin (TTR) iRNA compositions and methods of use thereof for treating or preventing TTR-associated diseases
#4899Multivalent oligonucleotide assemblies
#4900RNAi agents modified at the 4′-C position
#4901Agents useful in treating facioscapulohumeral muscular dystrophy
#4902Anti-PVRIG antibodies and methods of use
#4903Use of inhibitors of leukotriene B4 receptor BLT2 for treating asthma
#4904Polycationic methyl phospholipids for improved delivery of nucleic acids to eukaryotic cells
#4905MAO inhibitors and their conjugates as therapeutics for the treatment of brain cancer
#4906Use of liposomes in a carrier comprising a continuous hydrophobic phase for delivery of polynucleotides in vivo
#4907MultiLigand agent for drug delivery
#4908RNA interference functions as an antiviral immunity in mammals
#4909CaMKK-β as a target for treating cancer
#4910RNA complexes that inhibit melanin production
#4911Tools and Methods for Targeting Oligonucleotide Repeat RNA Toxicity
#4912Nucleic acid molecules to control insect pests
#4913Methods of Producing a Secreted Protein
#4914Small molecule conjugates for intracellular delivery of biologically active compounds
#4915Polycomb-associated non-coding RNAs
#4916Methods of modulating WARS2
#4917METHOD OF TREATING KELOIDS OR HYPERTROPHIC SCARS USING ANTISENSE COMPOUNDS TARGETING CONNECTIVE TISSUE GROWTH FACTOR (CTGF)
#4918Targeting molecule and a use thereof
#4919METHOD OF REGULATING GENE EXPRESSION
#4920Polyconjugates for Delivery of RNAi triggers to Tumor Cells In Vivo
#4921REDUCTION OF OFF-TARGET RNA INTERFERENCE TOXICITY
#4922Asymmetric bifunctional silyl monomers and particles thereof as prodrugs and delivery vehicles for pharmaceutical, chemical and biological agents
#4923Combination therapy for the treatment of autoimmune diseases
#4924Compositions and methods for nanoparticle lyophile forms
#4925PRP8 NUCLEIC ACID MOLECULES TO CONTROL INSECT PESTS
#4926SNAP25 NUCLEIC ACID MOLECULES TO CONTROL INSECT PESTS
#4927Pharmaceutical composition and method for reducing scar formation
#4928Composition for promoting chondrocyte differentiation or treating cartilage diseases, containing KLF10 expression inhibitor, and method for promoting cartilage differentiation by using same
#4929Method of Treating Cancer by Inhibition of DNA Repair Proteins
#4930ASYMMETRIC INTERFERING RNA COMPOSITIONS THAT SILENCE K-RAS AND METHODS OF USES THEREOF
#4931Low molecular weight cationic lipids for oligonucleotide delivery
#4932Methods of treating or preventing pruritis by blocking natriuretic polypeptide B
#4933Induction of thyroid iodide-handling gene expression in human cancers
#4934SGK1 INHIBITORS FOR TREATMENT OF PROSTATE CANCER
#4935RNA interference in skin indications
#4936Short interfering RNA (siRNA) analogues
#4937RNAi-mediated inhibition of connexin 43 for treatment of IOP-related conditions
#4938Methods used to treat cancer
#4939Inhibition of NEAT1 for treatment of solid tumors
#4940BIOLOGICAL MATERIALS AND THERAPEUTIC USES THEREOF
#4941DOWNREGULATION OF miR-7 FOR PROMOTION OF BETA CELL DIFFERENTIATION AND INSULIN PRODUCTION
#4942COMBINATION ANTI-HIV VECTORS, TARGETING VECTORS, AND METHODS OF USE
#4943Trialkyl cationic lipids and methods of use thereof
#4944Compositions and methods for treating diabetes
#4945Methods of using an activator of cereblon for neural cell expansion and the treatment of central nervous system disorders
#4946Microbubble complexes and methods of use
#4947TREATMENT OF NEURODEGENERATIVE AND NEURODEVELOPMENTAL DISEASES BY INHIBITION OF THE a2-Na/K ATPase/a-ADDUCIN COMPLEX
#4948Multi-targeting short interfering RNAs
#4949COMPOSITION FOR REDUCING CELLULAR SENESCENCE LEVEL INCLUDING ACTIVITY INHIBITOR INHIBITING DCUN1D3 ACTIVITY OR EXPRESSION INHIBITOR INHIBITING EXPRESSION OF DCUN1D3-ENCODING GENE AND USE THEREOF
#4950SiRNA targeting PRK2, which is hepatitis C virus therapeutic agent
#4951PROTEIN PHOSPHATASE INHIBITOR
#4952Method for treatment of heart failure
#4953HBV treatment
#4954Inhibitors of thioredoxin-interacting protein (TXNIP) for therapy
#4955Compositions and methods for reducing C/EBP homologous protein activity in myeloid-derived suppressor cells
#4956TAILED MIRTRON EFFECTORS FOR RNAI-MEDIATED GENE SILENCING
#4957SMALL RNA, PREPARATION METHOD THEREFOR AND APPLICATION THEREOF IN PHARMACEUTICALS FOR SPECIFICALLY UP-REGULATING GENE TRANSCRIPTIONAL ACTIVITY
#4958Compositions and methods for modulating an immune response
#4959Eukaryotic cells and methods for recombinantly expressing a product of interest
#4960Compounds for targeting drug delivery and enhancing siRNA activity
#4961Compounds for targeting drug delivery and enhancing siRNA activity
#4962Methods and Compositions for Inhibiting Mitochondrial Trafficking
#4963Methods for treating diet-induced obesity by decreasing or inhibiting P2Y2 purinergic receptor expression or activity
#4964RNAi inhibition of alpha-ENaC expression
#4965Polycomb-associated non-coding RNAS
#4966iRNA agents with biocleavable tethers
#4967Methods and compositions for the specific inhibition of gene expression by double-stranded RNA
#4968Molecular re-engineering of excitation-inhibition balance in memory circuits
#4969Oligonucleotide-ligand conjugates and process for their preparation
#4970METHOD OF TREATING CANCER
#4971Adeno-associated virus virions with variant capsid and methods of use thereof
#4972Biocompatible flavonoid compounds for organelle and cell imaging
#4973Adeno-associated virus virions with variant capsid and methods of use thereof
#4974MIKTO-ARM BRANCHED POLYMERS
#4975TYROSINE-PHOSPHORYLATED WBP2, A NOVEL CANCER TARGET AND BIOMARKER
#4976METHODS AND COMPOSITIONS INVOLVING CHITOSAN NANOPARTICLES
#4977COMPOSITIONS
#4978Peptide/particle delivery systems
#4979METHODS FOR DIAGNOSING AND TREATING MYHRE SYNDROME
#4980Modulation of NLGn4 expression, NK cell activity in non-alcoholic fatty liver disease (NAFLD)
#4981Polypeptides having peroxygenase activity
#4982Parental RNAI suppression of kruppel gene to control hemipteran pests
#4983RNAi targeting SEC61G
#4984RNAi-Mediated Inhibition of Tumor Necrosis Factor Alpha-Related Conditions
#4985COMPOSITIONS FOR BACTERIAL MEDIATED GENE SILENCING AND METHODS OF USING SAME
#4986Target point, preparation and method for treating human ADSL deficiency
#4987Double-stranded and single-stranded RNA molecules with 5′ triphosphates and their use for inducing interferon
#4988RNA interference mediated inhibition of hepatitis B virus (HBV) gene expression using short interfering nucleic acid (siNA)
#4989RNAi targeting CNTD2
#4990RNAi targeting ZNF205
#4991Modulation of transthyretin expression
#4992Polycation-functionalized nanoporous silicon carrier for systemic delivery of gene silencing agents
#4993Methods and compositions for treating solid tumors and enhancing tumor vaccines
#4994Compositions for in vivo expression of therapeutic sequences in the microbiome
#4995Site-specific delivery of nucleic acids by combining targeting ligands with endosomolytic components
#4996Molecular marker for cancer stem cell
#4997METHODS AND COMPOSITIONS FOR INHIBITING THE GROWTH AND/OR PROLIFERATION OF MYC-DRIVEN TUMOR CELLS
#4998Effect of PpeGID1c on vegetative growth of fruit trees
#4999Methods and compositions for neuroprotection
#5000METHODS AND COMPOSITIONS FOR THE DIAGNOSIS, CLASSIFICATION, AND TREATMENT OF CANCER
#5001Reagents and Methods for Treating Cancer
#5002Polynucleotides and methods for inhibiting cancer cells
#5003In vivo production of small interfering RNAs that mediate gene silencing
#5004COMPOSITIONS AND METHODS OF MODULATING B CELL RESPONSE
#5005Therapeutic targets for cancer progression
#5006KIDNEY DISEASE TARGETS AND USES THEREOF
#5007Methods of Using Interleukin-10 for Treating Diseases and Disorders
#5008TREATMENT OF CARDIAC DISEASES WITH MODULATORS OF THE HIPPO PATHWAY
#5009METHODS FOR CATEGORISING CANCER SUCH AS BREAST CANCER
#5010RNA POLYMERASE II33 NUCLEIC ACID MOLECULES TO CONTROL INSECT PESTS
#5011Oligonucleotide compounds for treatment of preeclampsia and other angiogenic disorders
#5012Method for selectively inhibiting ACAT1 in the treatment of obesity, metabolic syndrome, and atherosclerosis
#5013Control of Varroa mite infestation
#5014RNAi agents, compositions and methods of use thereof for treating transthyretin (TTR) associated diseases
#5015PROKARYOTIC RNAi-LIKE SYSTEM AND METHODS OF USE
#5016Polycomb-associated non-coding RNAs
#5017Oligonucleotide compounds for targeting huntingtin mRNA
#5018Polycomb-associated non-coding RNAs
#5019Double stranded oligonucleotide compounds comprising positional modifications
#5020Targeted therapeutic nucleosides and their use
#5021Anionic polyplexes for use in the delivery of nucleic acids
#5022Compositions and methods for modulating an immune response
#5023Blockade of CCL18 signaling via CCR6 as a therapeutic option in treating interstitial lung disease
#5024Compositions and Methods for Inhibition of PCSK9 Genes
#5025Gamma-secretase inhibition reduce APOC3 levels and plasma triglycerides
#5026Hybridosomes, compositions comprising the same, processes for their production and uses thereof
#5027SPT5 NUCLEIC ACID MOLECULES TO CONTROL INSECT PESTS
#5028MUCOSAL HEALING PROMOTER
#5029Compositions and methods for inhibiting expression of the PCSK9 gene
#5030RNA aptamers against BAFF-R as cell-type specific delivery agents and methods for their use
#5031NUCLEIC ACID CHEMICAL MODIFICATIONS
#5032POST-SYNTHETIC CHEMICAL MODIFICATION OF RNA AT THE 2'-POSITION OF THE RIBOSE RING VIA "CLICK" CHEMISTRY
#5033Compositions and methods for inhibiting gene expression of Hif2alpha
#5034Alternative export pathways for vector expressed RNA interference
#5035Compounds of chemically modified oligonucleotides and methods of use thereof
#5036Oligonucleotides and Methods for Treatment of Cardiomyopathy Using RNA Interference
#5037Oligonucleotides and methods for inhibiting or reducing bacterial biofilms
#5038Agents that modulate RGMb-neogenin-BMP signaling and methods of use thereof
#5039LONG NON-CODING RNA SPRY4-IT1 AS A DIAGNOSTIC AND THERAPEUTIC AGENT
#5040Nanoscale carriers for the delivery or co-delivery of chemotherapeutics, nucleic acids and photosensitizers
#5041SCREENING FOR TARGET-SPECIFIC AFFINITY BINDERS
#5042miR-211 expression and related pathways in human melanoma
#5043Ketohexokinase (KHK) iRNA compositions and methods of use thereof
#5044Treatment of vascular endothelial growth factor (VEGF) related diseases by inhibition of natural antisense transcript to VEGF
#5045Methods and compositions for the specific inhibition of gene expression by double-stranded RNA
#5046Compositions and Methods to Inhibit EZH2 for the Treatment of Cardiovascular Diseases
#5047Clonal analysis of functional genomic assays and compositions for practicing same
#5048In vitro method for identifying compounds of the Nav 1.9 sodium channel intended for the treatment of an inflammatory skin disease
#5049Wound healing compositions and treatments
#5050MAO inhibitors and their conjugates as therapeutics for the treatment of brain cancer
#5051Imino compounds for amphoteric liposomes and uses thereof
#5052Method of diagnosis, prognostic or treatment of neurodegenerative disease
#5053METHODS FOR DELIVERY OF siRNA TO THE SPINAL CORD AND THERAPIES ARISING THEREFROM
#5054Oligonucleotide modulators of the toll-like receptor pathway
#5055Anti-tumor therapy
#5056DOUBLE STRANDED RNA COMPOUNDS TO RHOA AND USE THEREOF
#50575′ triphosphate oligonucleotide with blunt end and uses thereof
#5058Bi-Functional Short-Hairpin RNA (Bi-shRNA) Specific for Single-Nucleotide KRAS Mutations
#50595′ triphosphate oligonucleotide with blunt end and uses thereof
#5060NUCLEIC ACID CAPABLE OF INHIBITING EXPRESSION OF BETA-2GPI
#5061Method of Treatment of Vascular Complications
#5062Compositions and methods for inhibition of expression of apolipoprotein C-III (APOC3) genes
#5063METHODS
#5064Molecular targets for healing or treating wounds
#5065Modulation of synaptic maintenance
#5066RNAi-Related Inhibition of TNF-alpha Signaling Pathway for Treatment of Ocular Angiogenesis
#5067Targeting WSB1 and pVHL to treat cancer
#5068METHODS AND COMPOSITIONS FOR PANIC DISORDERS
#5069Method for Regulating Cell Proliferation
#5070Cationic lipid
#5071Recurrent gene fusions in prostate cancer
#5072MicroRNAs and uses thereof
#5073COMPOSITION FOR PREVENTING OR TREATING OSTEOPOROSIS, CONTAINING PROGRANULIN INHIBITOR AS ACTIVE INGREDIENT
#5074Use of miR-494 to Modulate TRAIL-induced Apoptosis through BIM Down-regulation
#5075Multilayered nanoparticle and methods of manufacturing and using the same
#5076FULLY STABILIZED ASYMMETRIC SIRNA
#5077METHODS OF IMPROVED PROTEIN PRODUCTION USING MIRNAs AND SIRNAs
#5078Regulation of BARD1 expression by non-coding RNA
#5079NOVEL FUSION GENES AS FACTORS RESPONSIBLE FOR GASTRIC CANCER
#5080Targeted nanocarriers for the administration of immunosuppressive agents
#5081NANO DELIVERY SYSTEMS FOR SIRNA
#5082Lipids and lipid compositions for the delivery of active agents
#5083Treating neurodegenerative disease
#5084Synthesis of transcripts using Syn5 RNA polymerase
#5085Modulators of intracellular chloride concentration for treating down syndrome
#5086METHOD OF INDUCING AN IMMUNE RESPONSE
#5087Reduction of lipase activity in product formulations
#5088Composition for regenerating normal tissue from fibrotic tissue
#5089Manganese ion coated nanoparticles for delivery of compositions into the central nervous system by nasal insufflation
#5090METHOD AND PHARMACEUTICAL COMPOSITION FOR INHIBITING NEURONAL REMODELING
#5091Hippo and dystrophin complex signaling in cardiomyocyte renewal
#5092SYSTEM FOR CO-DELIVERY OF POLYNUCLEOTIDES AND DRUGS INTO PROTEASE-EXPRESSING CELLS
#5093Dual Targeting siRNA Agents
#5094Agents and methods to elicit anti-tumor immune response
#5095METHODS FOR TREATING ALLERGIC AIRWAY INFLAMMATION
#5096Polypeptides, nucleic acids and uses thereof
#5097Methods and pharmaceutical compositions for expressing a polynucleotide of interest in the retinal pigment epithelium of a subject
#5098Recombinant virus products and methods for inhibition of expression of myotilin
#5099Liposomal particles, methods of making same and uses thereof
#5100SiRNA and their use in methods and compositions for inhibiting the expression of the ORAI1 gene