109145 ⎘
Structure or type of the nucleic acid; Type of nucleic acid interfering N.A.
SYSTEMS AND METHODS FOR DIAGNOSING AND TREATING CANCER
#5402Methods and compositions for RNA-directed target DNA modification and for RNA-directed modulation of transcription
#5403Agents for improved delivery of nucleic acids to eukaryotic cells
#5404Interfering RNA molecules
#5405Preventive or therapeutic agent for fibrosis
#5406TARGETING DOMAIN AND RELATED SIGNAL ACTIVATED MOLECULAR DELIVERY
#5407RNA amidates and thioamidates for RNAi
#5408Adipocyte-targeting non-viral gene delivery system
#5409Reduced size self-delivering RNAi compounds
#5410NUCLEOTIDE SEQUENCE MOTIFS DIRECTING NUCLEIC ACID LOCATION TO EXTRACELLULAR VESICLES
#5411Compounds and methods for trans-membrane delivery of molecules
#5412Method for Inhibiting HIV Replication in Mammal and Human Cells
#5413SHIP INHIBITION TO COMBAT OBESITY
#5414Double-stranded ribonucleic acid as control against insects
#5415Treatment of hyperhidrosis
#5416METHOD OF SCREENING FOR CHAPERONIN MODULATOR
#5417Autoimmune disease treatments
#5418Methods and compositions for reducing immunosupression by tumor cells
#5419QSOX1 AS AN ANTI-NEOPLASTIC DRUG TARGET
#5420RESPIRATORY DISEASE-RELATED GENE SPECIFIC SIRNA, DOUBLE-HELICAL OLIGO RNA STRUCTURE CONTAINING SIRNA, COMPOSITON CONTAINING SAME FOR PREVENTING OR TREATING RESPIRATORY DISEASE
#5421Replication factor C-40 (RFC40/RFC2) as a prognostic marker and target in estrogen positive and negative and triple negative breast cancer
#5422COMPOSITIONS AND METHODS FOR MODULATION OF TARGET NUCLEIC ACIDS
#5423Dosages and methods for delivering lipid formulated nucleic acid molecules
#5424AGENTS FOR DOWNREGULATION OF THE ACTIVITY AND/OR AMOUNT OF BCL-XL AND/OR BCL-W
#5425SiRNA targeting HSR1
#5426PROTEIN INVOLVED IN DNA REPLICATION, AND MODULATION OF ITS ACTIVITY
#5427COMPOUNDS AND METHODS FOR TRANS-MEMBRANE DELIVERY OF MOLECULES
#5428Liposomes for modulating Wiskott-Aldrich syndrome protein
#5429In vitro method of inhibiting the growth of radioresistant laryngeal cancer cells
#5430Methods for identifying agents useful for modulating the expression and aggregation of CAG-expanded gene product in cells
#5431cgb2 And cgb1 Genes; Diagnosis, Monitoring And Treatment Of Cancer
#5432Modulation of NLGn4 expression, NK cell activity in non-alcoholic fatty liver disease (NAFLD)
#5433Inhibition of MAP4K4 through RNAi
#5434SILENCING OF POLO-LIKE KINASE EXPRESSION USING INTERFERING RNA
#5435RNA interference in ocular indications
#5436PROSTATE CANCER-SPECIFIC ALTERATIONS IN ERG GENE EXPRESSION AND DETECTION AND TREATMENT METHODS BASED ON THOSE ALTERATIONS
#5437Methods and compositions for the treatment of cancer
#5438Lipid encapsulating interfering RNA
#5439Compositions and methods for inhibiting expression of the ALAS1 gene
#5440Treatment of insulin resistance through inhibitors of transcription factor TSC22D4
#5441Anti-sense oligonucleotides targeted against exon 9 of IL-23R-alpha gene and method of using same to induce exon skipping and to treat inflammatory bowel diseases
#5442Methods for treating inflammatory responses or diseases caused by inflammation using ApoA-I binding protein (APOA1BP)
#5443Amine-containing lipidoids and uses thereof
#5444Role of a cluster of long noncoding RNA transcripts in protecting the heart from pathological hypertrophy
#5445MODULATORS OF ADP-DEPENDENT GLUCOKINASE (ADPGK) AND GLYCEROL-3-PHOSPHATE DEHYDROGENASE (GPD2) FOR THERAPY
#5446Delivering functional nucleic acids to mammalian cells via bacterially-derived, intact minicells
#5447Compositions and methods for insecticidal control of stinkbugs
#5448METHOD OF REGULATING CFTR EXPRESSION AND PROCESSING
#5449Method for inhibiting HIV replication in mammal and human cells
#5450Nucleic acid aptamers
#5451Complement component C5 iRNA compositions and methods of use thereof
#5452Single-Stranded Nucleic Acid Molecule for Controlling Gene Expression
#5453Modulation of HSP47 expression
#5454Inflammatory disease diagnosis and methods of treatment using lipopolysaccharides-responsive beige-like anchor
#5455Therapeutics for the induction of endogenous steroidogenesis and methods associated with their identification
#5456Compounds and methods for trans-membrane delivery of molecules
#5457Lipids and lipid compositions for the delivery of active agents
#5458Use of PKC-iota inhibitors for the treatment of breast cancer
#5459Porous nanoparticle-supported lipid bilayers (protocells) for targeted delivery and methods of using same
#5460CANCER EXAMINATION METHOD AND EXAMINATION KIT
#5461DOUBLE STRANDED RNA COMPOUNDS TO RHOA AND USE THEREOF
#5462Compositions and methods for inhibiting expression of the HAMP gene
#5463Protection against ionizing radiation and chemotherapy toxicity via latexin regulation
#5464IN VIVO PRODUCTION OF SMALL INTERFERING RNAS THAT MEDIATE GENE SILENCING
#5465Method of isolating nucleic acid
#5466Recurrent gene fusions in prostate cancer
#5467Matriptase inhibitors and uses thereof against orthomyxoviridae infections
#5468QSOX1 as an anti-neoplastic drug target
#5469Use of hydrogen sulfide synthesis inhibitors for cancer therapy
#5470Methods for diagnosis and treatment of amyotrophic lateral sclerosis based on an increased level of interaction between TDP-43 polypeptide and NF-KB P65 polypeptide
#5471Composition and method for inner ear sensory hair cell regeneration and replacement
#5472Lipid Formulated Compositions And Methods For Inhibiting Expression Of Transthyretin (TTR)
#5473Modulators of itch ubiquitinase activity
#5474METHODS AND USES INVOLVING GENETIC ABERRATIONS OF NAV3 AND ABERRANT EXPRESSION OF MULTIPLE GENES
#5475Compositions and methods for treating cancer
#5476NOVEL TREATMENT OF METABOLIC DISEASES
#5477Synthetic lethality in cancer
#5478Aptamer-RNAi therapeutic compositions
#5479Phase changing formulations of nucleic acid payloads
#5480Methods and compositions for enhancing the therapeutic effect of anti-tumor T cells
#5481Compositions and methods for the treatment of parkinson disease by the selective delivery of oligonucleotide molecules to specific neuron types
#5482Prophylactic and/or therapeutic agent for inflammatory disease, and method for screening prophylactic and/or therapeutic drug for inflammatory disease
#5483SiRNA TARGETING ETS1 AND ELK1 AND METHOD OF USING SAME IN THE INHIBITION OF CIP2A GENE IN CANCER TREATMENT
#5484Methods and compositions for stimulating reepithelialisation during wound healing
#5485METHODS, COMPOSITIONS AND KITS FOR PROMOTING MOTOR NEURON SURVIVAL AND TREATING AND DIAGNOSING NEURODEGENERATIVE DISORDERS
#5486Small Interfering RNA Delivery
#5487Foreign DNA surveillance protein
#5488Therapeutic compositions
#5489Nanoparticle mediated delivery of siRNA
#5490RNA aptamers against BAFF-R as cell-type specific delivery agents and methods for their use
#5491Compositions and methods for silencing marburg virus gene expression
#5492RNA interference mediated inhibition of hepatitis B virus (HBV) gene expression using short interfering nucleic acid (siNA)
#5493Phosphorous-linked oligomeric compounds and their use in gene modulation
#5494siRNA Therapy for Transthyretin (TTR) Related Ocular Amyloidosis
#5495A Novel EGFR Variant
#5496NOVEL SINGLE CHEMICAL ENTITIES AND METHODS FOR DELIVERY OF OLIGONUCLEOTIDES
#5497Hydrazinyl lipidoids and uses thereof
#5498Methods of identifying compounds for the treatment of fibrosis by using S1PR5
#5499Homeobox transcription factor ventx regulates differentiation and maturation of human dendritic cells
#5500Compositions and methods for “resistance-proof” SiRNA therapeutics for influenza
#5501RNAI MODULATION OF SCAP AND THERAPEUTIC USES THEREOF
#5502Short interfering nucleic acid (siNA) molecules containing a 2′ internucleoside linkage
#5503Polynucleotides and polypeptide sequences involved in the process of bone remodeling
#5504GLUTAMATE DEHYDROGENASE IN IDH1- AND IDH2-MUTATED CANCERS
#5505Composition for delivery of genetic material
#5506Brush-poly (glycoamidoamine)-lipids and uses thereof
#5507Fungal immunogens and related materials and methods
#5508Hydrazinyl lipidoids and uses thereof
#5509Method for treating breast cancer by targeting breast cancer stem cell
#5510Composition comprising inhibitor against PAPSS2 gene or protein encoded by gene for inducing senescence in tumor cells and method for inducing senescence in tumor cells using the same
#5511Down-regulating gene expression in insect pests
#5512Huntington's disease therapeutic compounds
#5513T-cell-specific humanized single fragment antibody delivery vehicle
#5514Compositions and methods for reducing neointima formation
#5515Lipopeptides for delivery of nucleic acids
#5516MOLECULAR TARGETS AND COMPOUNDS, AND METHODS TO IDENTIFY THE SAME, USEFUL IN THE TREATMENT OF FIBROTIC DISEASES
#5517Genetic amplification of IQGAP1 in cancer
#5518RNAi-mediated inhibition of histamine receptor H1-related conditions
#5519RNA interference mediated inhibition of gene expression using chemically modified short interfering nucleic acid (siNA)
#5520Antiproliferative agent
#5521Multi-targets interfering RNA molecules and their applications
#5522Methods and compositions for the specific inhibition of beta-catenin by double-stranded RNA
#5523Compositions comprising alternating 2′-modified nucleosides for use in gene modulation
#5524Biocompatible infinite coordination polymer nanoparticle-nucleic acid conjugates for antisense gene regulation
#5525Double stranded RNA constructs for aphid control
#5526Composition for controlling stem cells pluripotency, containing LIN28A methylation inhibitor, and method for screening for LIN28A methylation inhibitor
#5527Method for assaying microRNA, cancer therapeutic agent, and medicinal composition containing same for cancer therapy
#5528Bruton's tyrosine kinase as anti-cancer drug target
#5529Methods for preserving the viability of retinal ganglion cells in patients with glaucoma by an anti-TNF receptor 2 (anti-TNFR2) antibody
#5530Compositions and methods for treating HIF-1α over-expressing cancers
#5531METHOD OF TREATMENT OR PROPHYLAXIS INFTAMMATORY PAIN
#5532METHODS AND COMPOSITIONS FOR IMPROVING SLEEP AND MEMORY
#5533Bacterially-derived, intact minicells that encompass plasmid-free functional nucleic acid for in vivo delivery to mammalian cells
#5534B7-H4 EXPRESSION ON TUMOR VASCULATURE
#5535Viral and viral associated miRNAs and uses thereof
#5536P-coumaroyl-CoA:monolignol transferase
#5537Targeting chromatin modifiers for the treatment of medical conditions
#5538Treatment of sex hormone binding globulin (SHBG) related diseases by inhibition of natural antisense transcript to SHBG
#5539Small interference RNA for inhibiting intracellular expression of ribosomal protein S3
#5540Biodegradable and clinically-compatible nanoparticles as drug delivery carriers
#5541HSA-MIR-146B-5P-related nucleic acids and uses thereof
#5542Signal activated RNA interference
#5543Site-specific induction of bimolecular quadruplex-duplex hybrids and methods of using the same
#5544Method for inhibiting proliferation of high LIX1L-expressing tumor cell, and tumor cell proliferation-inhibiting peptide
#5545ApoIII and the Treatment and Diagnosis of Diabetes
#5546METHOD FOR THE DIAGNOSIS, PROGNOSIS, AND TRATMENT OF CANCER METASTASIS
#5547Mutations in DSTYK cause dominant urinary tract malformations
#5548Long interfering nucleic acid duplexes targeting multiple RNA targets
#5549Composition for treatment or metastasis suppression of cancers which includes p34 expression inhibitor or activity inhibitor as active ingredient
#5550Oligonucleotides for modulating gene expression and uses thereof
#5551In vivo delivery of oligonucleotides
#5552siRNA-mediated gene silencing
#5553FIBROBLAST GROWTH FACTOR RECEPTOR INHIBITION FOR THE TREATMENT OF DISEASE
#5554Biological Materials and Uses Thereof
#5555Modified Poly(Beta-Amino Ester)s for Drug Delivery
#5556Treatment of myocardial infarction by inhibiting the action of mAKAPβ
#5557Use of GPR83 to identify pruritus-related substances
#5558Biomarkers associated with BRM inhibition
#5559Non-liposomal systems for nucleic acid delivery
#5560Controlling fungal pathogens by disabling their small RNA pathways using RNAi-based strategy
#5561Pharmaceutical composition comprising Nanog shRNA, and method of using Nanog shRNA to treat cancer
#5562RNA sequence-specific mediators of RNA interference
#5563ORGANIC COMPOSITIONS TO TREAT HSF1-RELATED DISEASES
#5564Random RNAi libraries, methods of generating same, and screening methods utilizing same
#5565STRAIN OF DEFORMED WING VIRUS (DWV)
#5566Role for the perlman syndrome exonuclease Dis3l2 in the Lin28-let-7 pathway
#5567METHODS AND PHARMACEUTICALS COMPOSITIONS FOR TREATING BREAST CANCERS
#5568Methods for Promoting Reinnervation of Auditory Hair Cells
#5569Treatment of staphylococcal disorders
#5570Vectors for delivery of agents across biological membranes
#5571Fatty acids and their use in conjugation to biomolecules
#5572Therapeutic agent for fibroid lung
#5573Methods of using ZSCAN4 for rejuvenating human cells
#5574Methods and compositions related to T-cell activity
#5575FALZ for use as a target for therapies to treat cancer
#5576Therapeutic alteration of transplantable tissues through in situ or ex vivo exposure to RNA interference molecules
#5577Treatment of LCAT gene related diseases by inhibition of a natural antisense transcript to LCAT
#5578Treatment of lipid transport and metabolism gene related diseases by inhibition of natural antisense transcript to a lipid transport and metabolism gene
#5579TREATING TH2-MEDIATED DISEASES BY INHIBITION OF BROMODOMAINS
#5580miRNA BIOGENESIS IN EXOSOMES FOR DIAGNOSIS AND THERAPY
#5581Compositions and methods for inhibition of expression of protein C (PROC) genes
#5582Methods for increasing efficacy of lipid formulated siRNA
#5583Treating hepatitis B virus infections by administering receptor associated protein (RAP)
#5584Medicament for liver regeneration and for treatment of liver failure
#5585Polypeptide based block copolymer and the process for the preparation thereof, and the polymer micelles using the same
#5586Method for treating muscle-invasive bladder cancer, containing S100A9 and EGFR inhibitors and cisplatin as active ingredients
#5587COMPOSITIONS AND METHODS FOR INHIBITING EXPRESSION OF FACTOR VII GENE
#5588PCSK9 iRNA compositions and methods of use thereof
#5589Targeting microRNA miR-409-3P to treat prostate cancer
#5590Serpinc1 iRNA compositions and methods of use thereof
#5591Oligomeric compounds and compositions for use in modulation of small non-coding RNAs
#5592DOUBLE STRAND COMPOSITIONS COMPRISING DIFFERENTIALLY MODIFIED STRANDS FOR USE IN GENE MODULATION
#5593CHIMERIC OLIGOMERIC COMPOUNDS AND THEIR USE IN GENE MODULATION
#5594Method for expressing, secreting and transferring functional microRNAs/siRNAs and application thereof
#5595Selective targeting of cancer stem cells
#5596TIM RECEPTORS AS VIRUS ENTRY COFACTORS
#5597PHF20 AND JMJD3 COMPOSITIONS AND METHODS OF USE IN CANCER IMMUNOTHERAPY
#5598Lipid-Coated Albumin Nanoparticle Compositions and Methods of Making and Method of Using the Same
#5599Method for enhancing a function of a T cell
#5600Compositions and methods for reducing skin pigmentation
#5601METHODS TO PREDICT AND PREVENT RESISTANCE TO TAXOID COMPOUNDS
#5602Gene silencing of sugar-dependent 1 in
#5603Organic compositions to treat EPAS1-related diseases
#5604Method for inhibiting tumor growth through RNA-interference using liposomally associated CDC20 siRNA
#5605Method for treating and/or preventing myopia
#5606Methods of preserving and protecting pancreatic beta cells and treating or preventing diabetes by inhibiting NOX-1
#5607Complex of bi-specific antibody and digoxigenin conjugated to a therapeutic or diagnostic agent
#5608Therapeutic and diagnostic methods relating to cancer stem cells
#5609PHARMACEUTICAL COMPOSITION FOR TREATING CANCER
#5610METHODS FOR REGULATING HAIR GROWTH DISORDERS
#5611Rspondins as modulators of angiogenesis and vasculogenesis
#5612Biodegradable lipids for the delivery of active agents
#5613Method of altering vascular permeability and uses thereof
#5614Methods of treating cancer
#5615Tetrary gene delivery system for gene therapy and methods of its use
#5616BIOMARKERS FOR THE PREDICTION OF PRETERM BIRTH
#5617MOLECULAR TARGETS AND COMPOUNDS, AND METHODS TO IDENTIFY THE SAME, USEFUL IN THE TREATMENT OF DISEASES ASSOCIATED WITH EPITHELIAL MESENCHYMAL TRANSITION
#5618Methods for co-silencing expression of genes in filamentous fungal strains and uses thereof
#5619Compositions And Methods To Enhance Protein Expression
#5620Inhibition of SEMA3A in the prevention and treatment of ocular hyperpermeability
#5621RNAi-mediated inhibition of connexin 43 for treatment of IOP-related conditions
#5622Diagnostic and treatment for chronic and acute phase myeloid leukemia
#5623METHODS AND COMPOSITIONS FOR MANAGING VASCULAR CONDITIONS
#5624TOX INHIBITION FOR THE TREATMENT OF CANCER
#5625Notch inhibition in the prevention of vein graft failure
#5626Nanoparticles stabilized with nitrophenylboronic acid compositions
#5627Method and compositions for the genetic control of insect pests in cotton plants by chitin synthase gene silencing
#5628Methods of diagnosing, treating and monitoring diabetic retinopathy
#5629Methods to identify and treat subjects having corticosteroid-resistant asthma
#5630Modified oligonucleotides for telomerase inhibition
#5631Antisense oligonucleotides directed against connective tissue growth factor and uses thereof
#5632Influenza-activated constructs and methods of use thereof
#5633MODIFIED SMALL INTERFERING RNA MOLECULES AND METHODS OF USE
#5634CCCTC-Binding Factor (CTCF) RNA Interactome
#5635Oligonucleotide
#5636Treatment of metastatic tumors
#5637Composition for gene delivery comprising chitosan and liquid crystal formation material
#5638Process for formulating an anionic agent
#5639Lipid formulations for delivery of therapeutic agents to solid tumors
#5640Inhibitors of Branched-Chain-Aminotransferase-1 (BCAT1) for the Treatment of Brain Tumors
#5641Methods and compositions relating to the treatment of cancer
#5642STABLE TRANSFORMATION OF A POPULATION AND A METHOD OF BIOCONTAINMENT USING HAPLOINSUFFICIENCY AND UNDERDOMINANCE PRINCIPLES
#5643Furin-knockdown bi-functional RNA
#5644USE OF VEGFR1 AS A BIOMARKER
#5645Genetic control method and compositions against insect pests in cotton plants by the silencing of genes of the laccase family
#5646COMPOSITIONS AND METHODS OF INHIBITING GENE EXPRESSION IN A LUNG
#5647Compositions and methods for treating pancreatic cancer
#5648Cell-type specific aptamer-siRNA delivery system for HIV-1 therapy
#5649Methods to screen compounds for regulating USF1 activity and methods and compounds to treat cardiometabolic and lipid pathologies
#5650ShRNA molecules and methods of use thereof
#5651Intranuclear protein transduction through a nucleoside salvage pathway
#5652Positively charged polysaccharides for RNA transfection
#5653Suppression of malignant mesothelioma by overexpression or stimulation of endothelial protein C receptors (EPCR)
#5654Methods of treating cholangiocarcinoma
#5655PLATELETS TRANSFECTED BY EXOGENOUS GENETIC MATERIAL AND PLATELET MICROPARTICLES OBTAINED BY SAID TRANSFECTED PLATELETS, METHOD FOR THE PREPARATION AND USES THEREOF
#5656Low molecular weight cyclic amine containing cationic lipids for oligonucleotide delivery
#5657Inhibitors of miRNAs 221 and 222 for anti-tumor activity in multiple myeloma
#5658MODIFIED SMALL INTERFERING RNA MOLECULES AND METHODS OF USE
#5659Methods for treating eye disorders
#5660Methods and compositions for targeting immunoglobulins
#5661Compositions and methods for inhibiting gene expression of alpha-1 AntiTrypsin
#5662Method of producing dicer
#5663T cell balance gene expression, compositions of matters and methods of use thereof
#5664METHODS OF MODULATING DLK STABILITY
#5665INHIBITION OF THE COMPLEMENT SYSTEM
#5666Methods of modulating GABAergic inhibitory synapse formation and function
#5667Cancer antigen EEF2
#5668Lipids, lipid complexes and use thereof
#5669Technology for the Preparation of Microparticles
#5670Modulators of the interaction of astrin and raptor, and uses thereof in cancer therapy
#5671Transcription factor which regulates flavonoid, phenylpropanoid, tyrosine, and tryptophan pathways
#5672Compositions and methods for inhibiting expression of a target gene
#5673ANTIGENE OLIGOMERS INHIBIT TRANSCRIPTION
#5674MELK regulation for the treatment of breast cancer
#5675Lipid Formulated Compositions and Methods for Inhibiting Expression of a Gene from the Ebola Virus
#5676Methods of treating a metabolic syndrome by modulating heat shock protein (HSP) 90-beta
#5677Methods of inhibiting proliferation of estrogen-independent cancer cells
#5678Peptide-based in vivo siRNA delivery system
#5679Plants as functional microRNA and/or functional siRNA carriers, preparation methods and uses thereof
#5680Polyvalent RNA-nanoparticle compositions
#5681METHOD OF TREATING DELAYED HEALING OF A WOUND ASSOCIATED WITH DIABETES
#5682Methods and compositions involving miRNA and miRNA inhibitor molecules
#5683Method for diagnosis, prognosis and determination of treatment for cutaneous T-cell lymphoma
#5684DIAGNOSTIC MARKERS FOR TREATING CELL PROLIFERATIVE DISORDERS WITH TELOMERASE INHIBITORS
#5685METHODS FOR CONTROLLING STEM CELL DIFFERENTIATION
#5686Reduction of TGF beta signaling in myeloid cells in the treatment of cancer
#5687Methods and compositions for inducing deregulation of EPHA7 and ERK phosphorylation in human acute leukemias
#5688USP30 INHIBITORS AND METHODS OF USE
#5689siRNA FOR INHIBITION OF USP15 EXPRESSION AND PHARMACEUTICAL COMPOSITION CONTAINING THE SAME
#5690RNAi-related inhibition of TNF-alpha signaling pathway for treatment of ocular angiogenesis
#5691HBV treatment
#5692Compositions and methods to promote bone formation
#5693Methods and compositions involving miRNA and miRNA inhibitor molecules
#5694Methods of trans-differentiating a terminally differentiated target cell to a neuron
#5695Targeted sensitization of non-del(5q) malignant cells
#5696Cationic lipid
#5697FURTHER USE OF PROTEIN KINASE N BETA
#5698Polypeptides Having Cellulolytic Enhancing Activity And Polynucleotides Encoding Same
#5699Methods and compositions to modulate RNA processing
#5700RNA TARGETED TO C-MET