109145 ⎘
Structure or type of the nucleic acid; Type of nucleic acid interfering N.A.
Phosphoribosyl pyrophosphate synthetase 2 (PRPS2) as a therapeutic target in cancer treatment
#5702COMPOSITIONS AND METHODS TARGETING SIGNALING BY THE G PROTEIN BETA-GAMMA SUBUNIT FOR THE TREATMENT OF ASTHMA
#5703MUCOSAL HEALING PROMOTER
#5704Treatment of antiviral gene related diseases by inhibition of natural antisense transcript to an antiviral gene
#5705Methods and compositions for the production of siRNAs
#5706Oligomeric compounds and compositions for use in modulation of small non-coding RNAs
#5707Biological control of coleopteran pests
#5708Polypeptides Having Cellulolytic Enhancing Activity And Polynucleotides Encoding Same
#5709METHODS TO TREAT ALZHEIMER'S DISEASE USING APOE INHIBITORS
#5710METHODS FOR TREATING INFLAMMATION
#5711Inhibitors of atypical protein kinase C and their use in treating hedgehog pathway-dependent cancers
#5712METHODS FOR PRODUCING DOPAMINERGIC NEURONS AND USES THEREOF
#5713LDH inhibitors as treatment for fibrosis and fibrotic-related disorders
#5714Methods of treating an overweight subject
#5715Plant in which expression of a clathrin and/or coatomer subunit is suppressed or inhibited, a method for increasing the production of plant biomass and a method for producing a plant
#5716Pharmaceutical Compositions and Diagnostic Methods for Inflammatory Skin Diseases, Disorders or Conditions
#5717Methods of treating ischemia-reperfusion injury with siRNAs
#5718DESIGN OF OLIGONUCLEOTIDE ANALOGS AS THERAPEUTIC AGENTS
#5719Gene Silencing by Single-Stranded Polynucleotides
#5720LONG NON-CODING RNA USED FOR ANTICANCER THERAPY
#5721RNA INTERFERENCE TO ACTIVATE STEM CELLS
#5722Peptides useful for modulating histone demethylase function
#5723Apoptosis-inducing agent
#5724Systems and methods for diagnosing and treating cancer
#5725SATB1: A DETERMINANT OF MORPHOGENESIS AND TUMOR METASTATIS
#5726Molecular signatures of ovarian cancer
#5727METHOD OF PRODUCING BIOFUEL USING MICROALGAE CULTURES
#5728Nucleic acid molecules that confer resistance to coleopteran pests
#5729SEC23 NUCLEIC ACID MOLECULES THAT CONFER RESISTANCE TO COLEOPTERAN AND HEMIPTERAN PESTS
#5730Modified oligonucleotides for telomerase inhibition
#5731Modified oligonucleotides for telomerase inhibition
#5732Formulations for treating amyloidosis
#5733Post-synthetic orthogonal amidation plus metal catalyzed azide-alkyne cycloaddition click chemistry on siRNA
#5734Compositions and methods for functional nucleic acid delivery
#5735Methods and compositions of improved modified siRNA
#5736Treatment of B-cell lymphoma with microRNA
#5737COMPOUNDS AND METHODS FOR IMPROVED CELLULAR UPTAKE OF ANTISENSE COMPOUNDS
#5738Cancer treatment and immune system regulation through FAT10 pathway inhibition
#5739Production of therapeutic proteins in genetically modified mammalian cells
#5740Manipulation of hairy and enhancer of split 3 (Hes3) and its regulators/mediators as an anti-cancer strategy
#5741Identification of an inhibitor of iRhom1 or an inhibitor of iRhom2
#5742Mantle phenotype detection in palm
#5743Methods and compositions for detection of targets for autoimmune disease
#5744Transferrin/transferrin receptor-mediated siRNA delivery
#5745Methods of inhibiting cancer stem cells with HMGA1 inhibitors
#5746Compositions and methods for silencing apolipoprotein C-III expression
#5747Methods and compositions for the specific inhibition of CKAP5 by double-stranded RNA
#5748Signal activatable constructs and related components compositions methods and systems
#5749DOUBLE STRAND COMPOSITIONS COMPRISING DIFFERENTIALLY MODIFIED STRANDS FOR USE IN GENE MODULATION
#5750Identification of novel genes coding for small temporal RNAs
#5751Method for inhibiting calcification of a macrophage-derived matrix vesicle
#5752GENETIC DEVICE FOR THE CONTROLLED DESTRUCTION OF DNA
#5753Compositions and methods for selective delivery of oligonucleotide molecules to cell types
#5754Polypeptides having cellulolytic enhancing activity and polynucleotides encoding same
#5755Method for treating heart disease by inhibiting the Coxsackievirus-Adenovirus Receptor
#5756Disulfide masked prodrug compositions and methods
#5757Compositions and methods for polynucleotide transfection
#5758Amphipathic peptide
#5759Composition and method for treating a hematological malignancy
#5760Nutlin-3A for treatment of proliferative vitreoretinopathy
#5761Methods for diagnosing and treating prostate cancer
#5762Treatment-induced damage to the tumor micro-environment promotes cancer therapy resistance through extracellular proteins
#5763ACTIVITY-DEPENDENT GENE PAIRS AS THERAPEUTIC TARGETS AND METHODS AND DEVICES TO IDENTIFY THE SAME
#5764FLT3 receptor antagonists for the treatment or the prevention of pain disorders
#5765Multiple targeted RNAI for the treatment of cancers
#5766RNAI-mediated inhibition of frizzled related protein-1 for treatment of glaucoma
#5767UNA OLIGOMERS HAVING REDUCED OFF-TARGET EFFECTS IN GENE SILENCING
#5768Transthyretin allele selective UNA oligomers for gene silencing
#5769ANOIKIS RESISTANT PLACENTAL STEM CELLS AND USES THEREOF
#5770RNA interference agent, method for producing same, and use therefor
#5771DNA ASSIMILATION
#5772Reprogramming of human whartons jelly cells to produce hair cells
#5773Compositions and methods for the display of proteins on the surface of bacteria and their derived vesicles and uses thereof
#5774Treatment of human cytomegalovirus by modulating Wnt
#5775Nanoliposomal c-MYC-siRNA inhibits in vivo tumor growth of cisplatin-resistant ovarian cancer
#5776MEANS AND METHOD FOR DIAGNOSIS AND TREATMENT OF ALZHEIMER'S DISEASE
#5777Competitive modulation of microRNAs
#5778Composition for treating cancer associated with HPV infection
#5779Construction of pool of interfering nucleic acids covering entire RNA target sequence and related compositions
#5780Therapeutic applications of p53 isoforms in regenerative medicine, aging and cancer
#5781In vivo gene silencing by chemically modified and stable siRNA
#5782Treatment of reprogramming factor related diseases by inhibition of natural antisense transcript to a reprogramming factor
#5783MICROMIRs
#5784Compositions and methods for inhibiting hypdxia induced damage
#5785SHORT INTERFERING NUCLEIC ACID (siNA) COMPOSITIONS
#5786THERAPEUTIC AND DIAGNOSTIC TARGET GENE IN ACUTE MYELOID LEUKEMIA
#5787LOW-DENSITY LIPOPROTEIN ANALOGUE NANOPARTICLES, AND COMPOSITION COMPRISING SAME FOR TARGETED DIAGNOSIS AND TREATMENT OF LIVER
#5788Compositions and methods for inhibiting viral entry
#5789Methods for treating renal disease
#5790METHODS OF TREATMENT OF SKIN ULCERS
#5791Animal model for type 2 diabetes and obesity
#5792Method of treatment of SETDB1 expressing cancer
#5793Methods and Compositions for treatment of cancer by inhibition of NR2F6
#5794Sortilin 1 is a novel inducer of vascular calcification
#5795RNA-DIRECTED DNA CLEAVAGE BY THE Cas9-crRNA COMPLEX
#5796METHODS AND COMPOSITIONS TO PRODUCE ss-RNAi ACTIVITY WITH ENHANCED POTENCY
#5797Organic compositions to treat beta-catenin-related diseases
#5798Methods and products for preventing and/or treating metastatic cancer
#5799Methods for cancer management targeting Co-029
#5800Exosome transfer of nucleic acids to cells
#5801Short interference RNA gene delivery system for systemic circulation
#5802Method of promoting wound healing
#5803RNAi inhibition of alpha-ENaC expression
#5804PME-1 as a biomarker to predict and diagnose endometrial and breast cancer and gene silencing of PME-1 to inhibit epithelial to mesenchymal transition
#5805Organic compositions to treat HSF1-related diseases
#5806Therapeutics with conformationally restricted monomers
#5807Poly(vinyl ester) polymers for in vivo nucleic acid delivery
#5808Polymeric nanoparticles
#5809Synergistic anti-cancer composition and a process for the preparation thereof
#5810Method for establishing modified host cell
#5811Carboxylated polyamine derivatives as transfection reagents
#5812Organic compositions to treat beta-ENaC-related diseases
#5813Delivery of dsRNA to arthropods
#5814POLYMER CONJUGATES FOR DELIVERY OF BIOLOGICALLY ACTIVE AGENTS
#5815Polypeptides having peroxygenase activity
#5816TREATMENT OF CENTRAL NERVOUS SYSTEM (CNS) INJURY
#5817Compositions and methods for regulating arterial tone
#5818Triazine cationic polymers and methods of use thereof
#5819Modulation of CCR10 signals for treatment of skin and intestinal inflammatory diseases and infection
#5820Globo H and related anti-cancer vaccines with novel glycolipid adjuvants
#5821Agents for the prevention and/or treatment of central nervous system damage
#5822Lipidosome preparation, preparation method and application thereof
#5823Treatment of Sirtuin (SIRT) related diseases by inhibition of natural antisense transcript to a Sirtuin (SIRT)
#5824RNA silencing in animals as an antiviral defense
#5825RNA interference mediated inhibition of gene expression using chemically modified short interfering nucleic acid (siNA)
#5826Methods for treating apolipoprotein E4-associated disorders
#5827Methods for modulating C9ORF72 expression
#5828BIODEGRADABLE HYDROGEL FOR POLYNUCLEOTIDE DELIVERY
#5829Double-stranded oligonucleotide molecules to DDIT4 and methods of use thereof
#5830Polypeptides having cellulolytic enhancing activity and polynucleotides encoding same
#5831Therapies based on control of regulatory T cell stability and function via a neuropilin-1:semaphorin axis
#5832Lipids and compositions for the delivery of therapeutics
#5833Methods of treating hemoglobinopathies
#5834Androgen receptor variants and methods for making and using
#5835GALL WASP CONTROL AGENTS
#5836Composition and methods for the prevention and treatment of diet-induced obesity
#5837AMPHIREGULIN-SPECIFIC DOUBLE-HELICAL OLIGO-RNA, DOUBLE-HELICAL OLIGO-RNA STRUCTURE COMPRISING DOUBLE-HELICAL OLIGO-RNA, AND COMPOSITION FOR PREVENTING OR TREATING RESPIRATORY DISEASES CONTAINING SAME
#5838Modulation of human cytomegalovirus replication by micro-RNA 132 (miR132), micro-RNA 145 (miR145) and micro-RNA 212 (miR212)
#5839NICKED OR GAPPED NUCLEIC ACID MOLECULES AND USES THEREOF
#5840Treatment of uncoupling protein 2 (UCP2) related diseases by inhibition of natural antisense transcript to UCP2
#5841AGENT FOR TREATING RENAL FIBROSIS
#5842Gene silencing methods
#5843Hydroxylated polyamine derivatives as transfection reagents
#5844SiRNA and their use in methods and compositions for the treatment and/or prevention of eye conditions
#5845Short interfering ribonucleic acid (siRNA) for oral administration
#5846Polypeptides having peroxygenase activity
#5847CLUSTER OF DIFFERENTIATION 36 (CD36) AS A THERAPEUTIC TARGET FOR HIV INFECTION
#5848Antibodies and processes for preparing the same
#5849Nanotubes as carriers of nucleic acids into cells
#5850Method of treating cancer
#5851MODULATION OF PODOPLANIN MEDIATED PLATELET ACTIVATION
#5852Nanocarriers and their processing for diagnostics and therapeutics
#5853PREPARATION OF ANTIBODY OR AN ANTIBODY FRAGMENT TARGETED IMMUNOLIPOSOMES FOR SYSTEMIC ADMINISTRATION OF THERAPEUTIC OR DIAGNOSTIC AGENTS AND USES THEREOF
#5854Splice Switching Oligomers for TNF Superfamily Receptors and Their Use in Treatment of Disease
#5855METHODS AND COMPOSITIONS FOR ENHANCING DELIVERY OF DOUBLE-STRANDED RNA OR A DOUBLE-STRANDED HYBRID NUCLEIC ACID TO REGULATE GENE EXPRESSION IN MAMMALIAN CELLS
#5856Targets in multiple myeloma and other disorders
#5857Modulation of transthyretin expression
#5858Methods for treating and/or limiting development of diabetes
#5859NANOCOMPOSITES FOR IMAGING AND DRUG DELIVERY
#5860METHODS AND COMPOSITIONS FOR MODIFYING THE IMMUNE RESPONSE
#5861Use of isocitrate dehydrogenase 1 as a diagnostic and prognostic biomarker and therapeutic target for lung cancers
#5862Method for the treatment of cardiovascular fibrosis
#5863Compositions and Methods for Therapy and Diagnosis of Cancer and Cancer Metastasis
#5864COMPOSITION FOR SUPPRESSING EXPRESSION OF TARGET GENE
#5865Complement component C5 iRNA compositions and methods of use thereof
#5866Biotin complexes for treatment and diagnosis of alzheimer's disease
#5867LYVE-1 ANTAGONISTS FOR PREVENTING OR TREATING A PATHOLOGICAL CONDITION ASSOCIATED WITH LYMPHANGIOGENESIS
#5868Use of ADCY3 for diagnosis and treatment of gastric cancer
#5869Compositions and methods for controlling
#5870Compositions And Methods For Inhibiting Expression Of IKK-B Gene
#5871Pain treatment using ERK2 inhibitors
#5872THERAPEUTIC RNA SWITCHES COMPOSITIONS AND METHODS OF USE
#5873Compositions and Methods for Inhibiting Expression of a Gene from the JC Virus
#5874Recombinant RNA particles and methods of use
#5875Methods for producing a population of pancreatic beta-cells
#5876Methods and compositions for the specific inhibition of MYC by double-stranded RNA
#5877Polypeptides having peroxygenase activity
#5878Use of regulatory T cell-specific surface protein LRIG-1
#5879Asymmetric ionizable cationic lipid for RNA delivery
#5880Ionizable cationic lipid for RNA delivery
#5881POLYMERIC CARRIER
#5882Use of miR-494 to modulate TRAIL-induced apoptosis through BIM down-regulation
#5883Methods and compositions for treating cancer
#5884Polynucleotides having bioreversible groups
#5885ORGANIC COMPOSITIONS TO TREAT KRAS-RELATED DISEASES
#5886Nucleic acid molecules that target the vacuolar atpase C subunit and confer resistance to coleopteran pests
#5887TELOMERASE INHIBITORS FOR USE IN THERAPY
#5888Localized therapy of lower airways inflammatory disorders with proinflammatory cytokine inhibitors
#5889UNA oligomers targeting micro-RNA for therapeutics
#5890UNA duplex oligomers for therapeutics
#5891Methods targeting miR-128 for regulating cholesterol/lipid metabolism
#5892Compositions and methods for treatment of prostate and other cancers
#5893Methods and compositions for treating neurological disease
#5894EFFECTS OF APOLIPOPROTEIN B INHIBITION ON GENE EXPRESSION PROFILES IN ANIMALS
#5895Compositions and methods for treating hepatitis B
#5896POLYNUCLEOTIDE-POLY(DIOL) CONJUGATES, PROCESS OF PREPARATION AND USES THEREOF
#5897Treatment of pain by inhibition of USP5 de-ubiquitinase
#5898Transgenic plant of the species solanum tuberosum with resistance to phytophthora
#5899Treatment of fibroblast growth factor 21 (FGF21) related diseases by inhibition of natural antisense transcript to FGF21
#5900Treatment of adiponectin (ADIPOQ) related diseases by inhibition of natural antisense transcript to an adiponectin (ADIPOQ)
#5901Gene nanocomposite, and cellular internalization method of gene using same
#5902RNAi Inhibition of Serum Amyloid A For Treatment of Glaucoma
#5903Selective reactivation of genes on the inactive X chromosome
#5904Adeno-associated virus virions with variant capsid and methods of use thereof
#5905Method for regulating cell proliferation
#5906Pharmaceutical composition and uses thereof
#5907Inhibition of diacylglycerol kinase to augment adoptive T cell transfer
#5908SiRNA and their use in methods and compositions for the treatment and / or prevention of eye conditions
#5909Method for expression of small antiviral RNA molecules with reduced cytotoxicity within a cell
#5910COMPOSITIONS AND METHODS FOR MODULATION OF RORGAMMAT FUNCTIONS
#5911RNA synthesis—phosphoramidites for synthetic RNA in the reverse direction, and application in convenient introduction of ligands, chromophores and modifications of synthetic RNA at the 3′-end
#5912Compositions and methods for treating peripheral arterial disease
#5913RNAI BASED SELECTION SYSTEM
#5914Polypeptides having peroxygenase activity
#5915PROMOTER OF DIFFERENTIATION FROM HEPATIC PROGENITOR CELL INTO HEPATIC CELL, AND USE THEREOF
#5916Compositions for the delivery of RNA and drugs into cells
#5917Exosome-based therapeutics against neurodegenerative disorders
#5918Nucleic acids targeting TCTP for use in the treatment of chemo- or hormone-resistant cancers
#5919Lipid assemblies comprising anionic lysolipids and use thereof
#5920Compositions and methods for detecting and treating colorectal cancer
#5921Diagnosis and treatment of brain tumor
#5922COMPOSITIONS AND METHODS FOR ANALYZING HETEROGENEOUS SAMPLES
#5923Post-synthetic chemical modification of RNA at the 2′-position of the ribose ring via “click” chemistry
#5924Selective inhibition of polyglutamine protein expression
#5925Chiral control
#5926RNAI-BASED THERAPIES FOR CARDIOMYOPATHIES, MUSCULAR DYSTROPHIES AND LAMINOPATHIES
#5927Therapeutic method for pancreatic cancer
#5928Anandamide-modified nucleic acid molecules
#5929CONJUGATES, PARTICLES, COMPOSITIONS, AND RELATED METHODS OF USE
#5930Combination Therapy III
#5931PROCESSES AND COMPOSITIONS FOR LIPOSOMAL AND EFFICIENT DELIVERY OF GENE SILENCING THERAPEUTICS
#5932Predicting and treating diabetic complications
#5933PHOSPHATIDYLINOSITOL-3-KINASE C2 BETA MODULATORS AND METHODS OF USE THEREOF
#5934Compositions and methods for controlling
#5935Inhibition of oxidative stress in atrial fibrillation
#5936INHIBITORS OF BROMODOMAIN-CONTAINING PROTEIN PCAF FOR THE TREATMENT OF AUTOIMMUNE AND INFLAMMATORY DISEASES OR FOR THE TREATMENT OF CANCER
#5937CTLA-4 aptamer siRNA species
#5938CHEMICAL MODIFICATIONS OF MONOMERS AND OLIGONUCLEOTIDES WITH CYCLOADDITION
#5939Treatment of Myelodysplastic Syndrome by Inhibition of NR2F6
#5940Double-stranded oligonucleotide molecules to P53 and methods of use thereof
#5941Tetragalnac containing conjugates and methods for delivery of oligonucleotides
#5942Co-transcriptional assembly of modified RNA nanoparticles
#5943Polypeptides having cellulolytic enhancing activity and polynucleotides encoding same
#5944Di-aliphatic substituted pegylated lipids
#5945Aminoalcohol lipidoids and uses thereof
#5946Compositions for targeted delivery of siRNA
#5947Soluble MANF in pancreatic β-cell disorders
#5948Methods and compositions for the specific inhibition of androgen receptor by double-stranded RNA
#5949EpCAM aptamer for detection of cancer stem cells
#5950Multi-conjugate of siRNA and preparing method thereof
#5951RNAI EXPRESSION CONSTRUCTS
#5952Structurally designed shRNAs
#5953Oral delivery of nucleic acid-based gene interfering agents by
#5954Agent for treating cancer
#5955Modified RNAi agents
#5956Methods and compositions for treating prostate cancer
#5957LEPIDOPTERAN INSECT N-ACETYLGLUCOSAMINIDASE GENES AND THEIR USE IN GLYCOENGINEERING
#5958Therapeutic alteration of transplantable tissues through or exposure to RNA interference molecules
#5959Aptamer-targetted antigen delivery
#5960Composition comprising material for inhibiting SCF or receptor thereof for treating or preventing diseases associated with vascular permeability
#5961Recombinant DNA for gene suppression
#5962Ligand-conjugated monomers
#5963Lipid compositions
#5964Method to treat or prevent herpesvirus infections
#5965INHIBITORS OF NKX2.5 FOR VASCULAR REMODELLING
#5966Compositions Comprising RAC Mutants, and Methods of Use Thereof
#5967Simultaneous detection of cannibalism and senescence as prognostic marker for cancer
#5968Bacteria mediated gene silencing
#5969Diagnostic and screening methods for atopic dermatitis
#5970EML4-ALK fusion gene
#5971Methods and compositions for the specific inhibition of glycolate oxidase (HAO1) by double-stranded RNA
#5972USE OF COX-3 BINDING MOLECULES FOR MODULATING AUTOPHAGY
#5973TRANSLOCATION AND MUTANT ROS KINASE IN HUMAN NON-SMALL CELL LUNG CARCINOMA
#5974NEW TREATMENT FOR NEURODEGENERATIVE DISEASES
#5975Use of nanodiamonds for generating free radicals for therapeutic purposes under radiation
#5976Use of SIRT7 as novel cancer therapy target and method for treating cancer using the same
#5977Ras opposite (ROP) and related nucleic acid molecules that confer resistance to coleopteran and/or hemipteran pests
#5978TARGET GENES FOR CONTROL OF PLANT PARASITIC NEMATODES AND USE OF SAME
#5979Methods of identifying and treating glioblastoma
#5980Nucleic acid molecules that confer resistance to coleopteran pests
#5981Methods of inducing insulin production
#5982Highly efficient method for establishing induced pluripotent stem cell
#5983Cationic lipid
#5984MODIFICATION OF THE IMMUNOMODULATORY EFFECTS OF CELLS
#5985Diagnostic and treatment methods in subjects having or at risk of developing resistance to cancer therapy
#5986Oligomeric compounds and methods
#5987RNAi-MEDIATED INHIBITION OF HIF1A FOR TREATMENT OF OCULAR ANGIOGENESIS
#5988Repressor on IFN-λ promoter and siRNA against GATA1, EVI1, and CRX to alter IFN-λ gene activity
#5989Aptamer-mRNA conjugates for targeted protein or peptide expression and methods for their use
#5990Treatment of NANOG related diseases by inhibition of natural antisense transcript to NANOG
#5991METHODS FOR TREATING MDS1-EVI1 MEDIATED CANCER
#5992Therapeutic oligonucleotides comprising pyrazolotriazine nucleotide analogues
#5993Particle-nucleic acid conjugates and therapeutic uses related thereto
#5994METHODS AND COMPOSITIONS FOR PEROXISOME PROLIFERATOR-ACTIVATED RECEPTOR GAMMA COACTIVATOR-1alpha (PGC1alpha) AS A TARGET OF CIRCULATING TUMOR CELLS
#5995Lipid formulations
#5996Low density lipoprotein receptor-mediated siRNA delivery
#5997Stable non-aggregating nucleic acid lipid particle formulations
#5998Wnt signaling inhibitor comprising insulin-like growth factor-binding protein
#5999Combination of DNA repair inhibition with bendamustine or gemcitabine in the treatment of cancer
#6000Lipid formulations for nucleic acid delivery