109145 ⎘
Structure or type of the nucleic acid; Type of nucleic acid interfering N.A.
Means for inhibiting the expression of ANG2
#6302Lin28-mediated control of let-7 biogenesis
#6303METHOD FOR IMPROVING THE SUCCESS RATE OF HEMATOPOIETIC STEM CELL TRANSPLANTS
#6304tRNA derived small RNAs (tsRNAs) involved in cell viability
#6305gene in cancer and inflammation
#6306PME-1 as a biomarker to predict and diagnose an increased risk of endometrial cancer and gene silencing of PME-1 to inhibit epithelial to mesenchymal transition
#6307Targeting domain and related signal activated molecular delivery
#6308Methods and compositions for enhancing the efficacy and specificity of RNA silencing
#6309Methods of regulating angiogenesis by administering agents which increase apoB-100 polypeptide
#6310Expanding hematopoietic stem cells
#6311Methods of using ZSCAN4 for rejuvenating human cells
#6312Modified iRNA agents
#6313Methods and compositions for the specific inhibition of met by double stranded RNA
#6314Double-stranded nucleic acid molecule for gene expression control
#6315Methods for treating chronic pain
#6316Compositions and methods for treatment of prostate and other cancers
#6317Delivering functional nucleic acids to mammalian cells via bacterially-derived, intact minicells
#6318RNAi agents, compositions and methods of use thereof for treating transthyretin (TTR) associated diseases
#6319Methods and compositions involving miRNA and miRNA inhibitor molecules
#6320Recombinant polypeptides for membrane fusion and uses thereof
#6321Modified parvovirus useful for gene silencing
#6322Therapeutic compositions
#6323Combination anti-HIV vectors, targeting vectors, and methods of use
#6324Induced pluripotent stem cells with synthetic modified RNAs
#6325Method for selectively inhibiting ACAT1 in the treatment of neurodegenerative diseases
#6326Reduction of off-target RNA interference toxicity
#6327Auto-recognizing therapeutic RNA/DNA chimeric nanoparticles (NP)
#6328Lipids and lipid compositions for the delivery of active agents
#6329Pharmaceutical composition comprising NANOG SHRNA, and method of using NANOG SHRNA to treat cancer
#6330Delaying the progression of diabetes
#6331Genetic alterations in glioma
#6332Process for purifying VLPs
#6333Inhibitors of metastasis
#6334MCPIP protection against osteoclast production
#6335Complement antagonists and uses thereof
#6336Induction of thyroid iodide-handling gene expression in human cancers
#6337Nucleic acid molecules that confer resistance to coleopteran pests
#6338Compositions and methods for inhibiting expression of the HAMP gene
#6339Means and methods for treating and/or preventing natural AHR ligand-dependent cancer
#6340Targets for regulation of angiogenesis
#6341Method for nucleic acid delivery using hyaluronic acid
#6342Methods and compositions for the specific inhibition of beta-catenin by double stranded RNA
#6343Methods of treating cancer
#6344Treatment of antiviral gene related diseases by inhibition of natural antisense transcript to an antiviral gene
#6345Preventive or therapeutic agent for fibrosis
#6346Dendronized polymers for nucleic acid delivery
#6347RNA interference suppression of neurodegenerative diseases and methods of use thereof
#6348Methods and compositions for enhancing the efficacy and specificity of single and double blunt-ended siRNA
#6349Treatment of heart disease by inhibition of the action of ribosomal S6 kinase 3 (RSK3)
#6350miRNA-212/132 family as a therapeutic target
#6351Uses of the human ZFX gene and drugs associated with same
#6352Compositions and methods for treating cancer
#6353Compositions and methods to control insect pests
#6354Use of antagonists of growth hormone or growth hormone receptor to prevent or treat stress-sensitive psychiatric illness
#6355Epigenetic biomarker ZNF545 for diagnosing and prognosis of gastric cancer
#6356Conserved HBV and HCV sequences useful for gene silencing
#6357Targeting CLPTM1L by RNA interference for treatment and prevention of cancer
#6358Modulation of transthyretin expression
#6359Site specific delivery of nucleic acids by combining targeting ligands with endosomolytic components
#6360Methods and compositions for the treatment of huntington's disease
#6361Use of leucyl tRNA synthetase
#6362Compositions and methods for silencing aldehyde dehydrogenase
#6363siRNA useful in the treatment of flavivirus infection
#6364Antibody against mutant α-actinin-4
#6365Compositions and methods for inhibiting expression of a gene from the Ebola virus
#6366PHOSPHOLIPID-DETERGENT CONJUGATES AND USES THEREOF
#6367KRT19 stabilizing HER2 and use thereof
#6368Therapeutic nanoparticles and methods of use thereof
#6369Methods and compositions for enhancing the therapeutic effect of anti-tumor T cells
#6370Short interfering RNA (siRNA) analogues
#6371Method of classifying antibody, method of identifying antigen, method of obtaining antibody or antibody set, method of constructing antibody panel and antibody or antibody set and use of the same
#6372Modulation of HSP47 expression
#6373Method to trigger RNA interference
#6374Method for decreasing radioresistance and growth, metastasis and infiltration of cancer cells through regulating expression or activity of TM4SF4 in non-small cell lung cancer
#6375Methods and compositions for reducing amyloid beta levels
#6376Method for therapeutic angiogenesis
#6377Methods of introducing dsRNA to plant seeds for modulating gene expression
#6378Genes and polypeptides relating to breast cancers
#6379Methods and compositions involving MicroRNA
#6380Cell penetrating peptides for intracellular delivery of molecules
#6381Nogo receptor antagonists and methods of increasing neurite outgrowth
#6382Bacterially-derived, intact minicells that encompass plasmid-free functional nucleic acid for in vivo delivery to mammalian cells
#6383Ameliorating oxidative stress in neurodegenerative disease via Nox1 targeting
#6384Method and medicament for inhibiting the expression of a given gene
#6385Methods for treating Niemann-Pick type C disease
#6386Method and medicament for inhibiting the expression of a given gene
#6387LRP1 as key receptor for the transfer of sterified cholesterol from very-low-density lipoproteins (VLDL) to ischaemic cardiac muscle
#6388Method of inhibiting cancer in a mammal by administering an antibody to PTHrP
#6389MOLECULAR TARGETS FOR HEALING OR TREATING WOUNDS
#6390Methods for treatment of cancer by targeting Sirt5
#6391Downregulation of miR-7 for promotion of beta cell differentiation and insulin production
#6392Methods for producing interfering RNA molecules in mammalian cells and therapeutic uses for such molecules
#6393Targeting the steroidogenic pathway for treating and/or preventing allergic diseases
#6394Compositions and methods for inhibiting expression of factor V
#6395Compositions and methods for treating colon cancer
#6396Down regulation of the gene expression by means of nucleic acid-loaded virus-like particles
#6397Compositions and methods for inhibiting expression of transthyretin
#6398Compositions and methods for inhibiting expression of TMPRSS6 gene
#6399Interfering RNA delivery system and uses thereof
#6400Methods for creating and identifying functional RNA interference elements
#6401Control of gene expression
#6402Modulation of angiopoietin-like 3 expression
#6403Methods used in sensitizing invasive glioblastoma to therapeutic treatment
#6404Mitochondrial ribosomal proteins as aging regulators
#6405Inhibitor of neuronal connectivity linked to schizophrenia susceptibility and cognitive dysfunction
#6406Methods of modulating compliance of the trabecular meshwork
#6407Treatment of frataxin (FXN) related diseases by inhibition of natural antisense transcript to FXN
#6408Protection against endothelial barrier dysfunction through inhibition of the tyrosine kinase abl-related gene (ARG)
#6409Anti-sense oligonucleotides targeted against exon 9 of IL-23Rα gene and method of using same to induce exon skipping and to treat inflammatory bowel diseases
#6410Cochleate compositions directed against expression of proteins
#6411Tumor associated vaccines and compositions for disrupting tumor-derived immunosuppression for use in combination cancer immunotherapy
#6412Angiopoietin-like 3 (ANGPTL3) iRNA compositions and methods of use thereof
#6413Phase changing formulations of nucleic acid payloads
#6414Reduction of ALMS1 gene expression or inhibition of altröm protein to induce cardiomyocyte proliferation
#6415In vivo production of small interfering RNAs that mediate gene silencing
#6416Lipid formulated compositions and methods for inhibiting expression of serum amyloid A gene
#6417pRNA multivalent junction domain for use in stable multivalent RNA nanoparticles
#6418Modified siRNA molecules and uses thereof
#6419Alternative export pathways for vector expressed RNA interference
#6420Theranostic imaging agents and methods of use
#6421Single-stranded nucleic acid molecule having nitrogen-containing alicyclic skeleton
#6422Composition for inhibiting angiogenesis containing a peroxidasin inhibitor as an active ingredient
#6423RNAi-mediated inhibition of phosphodiesterase type 4 for treatment of cAMP-related ocular disorders
#6424Single-stranded nucleic acid molecule having nitrogen-containing alicyclic skeleton
#6425Compositions and methods for treatment of tamoxifen resistant breast cancer
#6426Nanotubes as carriers of nucleic acids into cells
#6427RNA interference suppression of neurodegenerative diseases and methods of use thereof
#6428Combined inhibition of the vitamin D receptor and DNA replication in the treatment of cancer
#6429Methods of modulating MicroRNAs in the treatment of pulmonary arterial hypertension
#6430Methods and compositions for controlling efficacy of RNA silencing
#6431Amine-containing lipidoids and uses thereof
#6432Platelet derived growth factor receptor supports cytomegalovirus infectivity
#6433Micro-RNA's that regulate muscle cells
#6434Methods of treating a metabolic syndrome by modulating heat shock protein (HSP) 90-β
#6435Compositions and methods for treating, diagnosing and monitoring disease
#6436Insect-combating preparation and method based on RNAi technology
#6437Compositions and methods for inhibiting expression of CD274/PD-L1 gene
#6438Methods and compositions for selecting siRNA of improved functionality
#6439Compositions and methods of preventing or ameliorating abnormal thrombus formation and cardiovascular disease
#6440Compositions and methods for inhibition of expression of protein C (PROC) genes
#6441Polycomb-associated non-coding RNAs
#6442Hepatitis C dsRNA effector molecules, expression constructs, compositions, and methods of use
#6443Medicament for liver regeneration and for treatment of liver failure
#6444Combination therapy
#6445Method of treatment of breast cancers over-expressing the SHP2 signature genes
#6446Compositions and method for inhibiting hepcidin antimicrobial peptide (HAMP) or HAMP-related gene expression
#6447Micro-RNAs and micro-RNA inhibitors to modulate blood vessel growth, patterning, tumor growth and malignant disease and method for making and using them
#6448Oligomeric compounds and compositions for use in modulation of small non-coding RNAs
#6449Microrna (miRNA) and downstream targets for diagnostic and therapeutic purposes
#6450Compositions and methods for inhibition of expression of apolipoprotein C-III (APOC3) genes
#6451Method of treating cancer by inhibition of DNA repair proteins
#6452RNA interference in dermal and fibrotic indications
#6453Mammalian receptors as targets for antibody and active vaccination therapy against mold infections
#6454Organic compositions to treat Beta-ENaC-related diseases
#6455Methods and compositions for the specific inhibition of MYC by double-stranded RNA
#6456Compositions and methods for inhibiting expression of a target gene
#6457Methods and compositions for high efficiency transfection of siRNA
#6458Modulators of Plexin B2 activity
#6459RNA interference mediated inhibition of isocitrate dehydrogenase (IDH1) gene expression
#6460SiRNA sequence-independent modification formats for reducing off-target phenotypic effects in RNAi, and stabilized forms thereof
#6461Regulators of NFAT and/or store-operated calcium entry
#6462VEGF-D/VEGFR2/3-mediated regulation of dendrites
#6463Modified siRNA molecules incorporating 5-fluoro-2′-deoxyuridine residues to enhance cytotoxicity
#6464RNAi-mediated inhibition of histamine receptor H1-related conditions
#6465Matriptase inhibitors and uses thereof against orthomyxoviridae infections
#6466Methods for treating castration resistant prostate cancer and metastasis by reducing B-cell number and/or function
#6467Porous nanoparticle-supported lipid bilayers (protocells) for targeted delivery and methods of using same
#6468Vector for pulmonary delivery, inducing agent, and uses
#6469Efficient protein expression in vivo using modified RNA (MOD-RNA)
#6470Modified small interfering RNA molecules and methods of use
#6471Bruton's tyrosine kinase as anti-cancer drug target
#6472Methods and compositions for RNA-directed target DNA modification and for RNA-directed modulation of transcription
#6473Compositions and methods for treatment of ear disorders
#6474Prostate carcinogenesis predictor
#6475Agents that reduce neuronal overexcitation
#6476dsRNA for treating viral infection
#6477Oligomeric compounds and compositions for use in modulation of small non-coding RNAS
#6478Compositions and methods for the treatment of cancer
#6479Repressor on IFN-λ promoter and siRNA against ZEB1 and BLIMP-1 to increase IFN-λ gene activity
#6480Anti-DCLK1 monoclonal antibodies and methods of production and use thereof
#6481Nucleic acid aptamers
#6482Treating hepatitis C virus infection
#6483Compositions and methods for inhibiting expression of an RNA from west nile virus
#6484Methods targeting miR-128 for regulating cholesterol/lipid metabolism
#6485Micro-RNAs of the miR-15 family modulate cardiomyocyte survival and cardiac repair
#6486Method and medicament for inhibiting the expression of a given gene
#6487Methods for diagnosing and treating neuroendocrine cancer
#6488RNAi modulation of ApoB and uses thereof
#6489Methods and compositions for the diagnosis, classification, and treatment of cancer
#6490Methods and compositions for promoting survival and proliferation of endothelial cells and stimulating angiogenesis
#6491Human micrornas and methods for inhibiting same
#6492Method for selectively inhibiting ACAT1 in the treatment of alzheimer's disease
#6493RNAi pharmaceutical composition for suppressing expression of KRAS gene
#6494B-type plexin antagonists and uses thereof
#6495Molecular marker for cancer stem cell
#6496Organic compositions to treat HSF1-related diseases
#6497Multi-conjugate of siRNA and preparing method thereof
#6498Pancreatic cancer biomarker using the characteristics of pancreatic cancer stem cells, and use thereof
#6499Lipid nano particles comprising cationic lipid for drug delivery system
#6500Amino acid lipids and uses thereof
#6501Modulation of LRCH4 activity and therapeutic application thereof
#6502Composition comprising expression or activity inhibitors of Ninjurin1 for the prevention and treatment of inflammatory disease
#6503siRNA targeting VEGFA and methods for treatment in vivo
#6504Method of treatment
#6505Recombinant polypeptide production method
#6506Compositions and methods for increasing erythropoietin (EPO) production
#6507Methods and compositions for the treatment of eye disorders with increased intraocular pressure
#6508Compositions and methods for inhibiting expression of klf-1 and bcl11a genes
#6509MicroRNAs and uses thereof
#6510Compositions and methods for treating leukemia
#6511Use of DR6 and p75 antagonists to promote survival of cells of the nervous system
#6512SiRNA against Cbl-b and optionally IL-2 and IL-12 for use in the treatment of cancer
#6513Compositions and methods for treating lung disease and injury
#6514Biological inhibitors of ROR1 capable of inducing cell death
#6515Methods and compositions for the specific inhibition of gene expression by double-stranded RNA
#6516Lipid formulated compositions and methods for inhibiting expression of Eg5 and VEGF genes
#6517SiRNA compositions and methods for treatment of HPV and other infections
#6518Composition and method for oligonucleotide delivery
#6519Method for suppressing receptor tyrosine kinase-mediated pro-survival signaling in cancer cell
#6520Repressor on IFN-λ promoter and siRNA against ZEB1 and BLIMP-1 to increase IFN-λ gene activity
#6521TAZ/WWTR1 for diagnosis and treatment of cancer
#6522BACH2 repression in cells
#6523Sp35 antibodies and uses thereof
#6524Methods for modulating the expression and aggregation of a CAG-expanded gene product in cells and methods for identifying agents useful for doing the same
#6525Metabolic gene, enzyme, and flux targets for cancer therapy
#6526Composition comprising expression or activity regulators of AKAP12 for treating central nerve system diseases
#65275′-end derivatives
#6528RNA molecules that upregulate insulin production
#6529Selective reduction of the deleterious activity of extended tri-nucleotide repeat containing genes
#6530Serpinc1 iRNA compositions and methods of use thereof
#6531Modified iRNA agents
#6532Lipid nanoparticle compositions for antisense oligonucleotides delivery
#6533Genetic amplification of IQGAP1 in cancer
#6534Lipid-polymer hybrid particles
#6535Inhibitors of branched-chain-aminotransferase-1 (BCAT1) for the treatment of brain tumors
#6536Methods and compositions for enhancing the efficacy and specificity of RNA silencing
#6537Antagonists of GRASP55 for use as a medicament
#6538METHODS AND COMPOSITIONS FOR MAINTENANCE OF A FUNCTIONAL WOUND
#6539Methods and compositions for the specific inhibition of HIF-1α by double-stranded RNA
#6540Therapeutic uses of inhibitors of RTP801L
#6541Combination of DNA repair inhibition with bendamustine or gemcitabine in the treatment of cancer
#6542Oligonucleotide compositions with enhanced efficiency
#6543Therapeutic applications of P53 isoforms in regenerative medicine, aging and cancer
#6544Feeder-free derivation of human-induced pluripotent stem cells with synthetic messenger RNA
#6545HBV treatment
#6546MicroRNA biomarkers for human breast and lung cancer
#6547Method for expression of small antiviral RNA molecules with reduced cytotoxicity within a cell
#6548Down-regulating gene expression in insect pests
#6549Methods of inducing insulin production
#6550Compositions for conferring tolerance to viral disease in social insects, and the use thereof
#6551Synthetic lethality in cancer
#6552Methods for alleviating facioscapulohumeral dystrophy (FSHD) by N siRNA molecule inhibiting the expression of DUX4-FL
#6553dsRNA molecules comprising oligonucleotide analogs having modified intersubunit linkages and/or terminal groups
#6554iRNA agents with biocleavable tethers
#6555Peptide-based in vivo siRNA delivery system
#6556Compositions and methods for inhibiting expression of the ALAS1 gene
#6557MicroRNA target site for cell- or tissue-specific inhibition of expression of a transgene
#6558Methods and compositions for RNAi-based cancer treatment
#6559SiRNA against p22phox
#6560Compositions and methods for inhibiting expression of Eg5 gene
#6561RNAi modulation of SCAP and therapeutic uses thereof
#6562Methods and kits for synthesis of siRNA expression cassettes
#6563Nucleic acid molecules inducing RNA interference, and uses thereof
#6564Therapeutic alteration of transplantable tissues through in situ or ex vivo exposure to RNA interference molecules
#6565Agent for treating myelofibrosis
#6566Gene silencing by single-stranded polynucleotides
#6567Nucleic acids targeting TCTP for use in the treatment of chemo- or hormone-resistant cancers
#6568Compositions and methods for treatment of drug resistant multiple myeloma
#6569Method to trigger RNA interference
#6570Protease degradable polypeptides and uses thereof
#6571Methods targeting miR-33 microRNAs for regulating lipid metabolism
#6572Compositions for targeted delivery of siRNA
#6573Identification of novel genes coding for small temporal RNAs
#6574RNAi sequence-independent modification formats, and stabilized forms thereof
#6575Methods of treating obesity by inhibiting nicotinamide N-methyl transferase (NNMT)
#6576Nanotopography-mediated reverse uptake platform for nucleic acid delivery and applications thereof
#6577Nucleic acid having an anti-metabolic syndrome effect
#6578Down-regulating gene expression in insect pests
#6579Short interfering ribonucleic acid (siRNA) for oral administration
#6580Modulation of immune responses by the poxviral K4 protein
#6581Myomegalin variant 8
#6582Genetic inhibition by double-stranded RNA
#6583Inhibitors of SP140 and their use in therapy
#6584SiRNA targeting ETS1 and ELK1 and method of using same in the inhibition of CIP2A gene in cancer treatment
#6585Combinations of TGFβ and COX-2 inhibitors and methods for their therapeutic application
#6586MicroRNA-based short hairpin RNA for gene knockdown of NR1 subunit of N-methyl-D-aspartate receptor and its application on pharmaceutics
#6587SiRNA compositions and methods for potently inhibiting viral infection
#6588Methods and compositions for the treatment of cancer
#6589RNA interference mediated inhibition of gene expression using short interfering nucleic acids (siNA)
#6590Polynucleotides for reducing respiratory syncytial virus gene expression
#6591Cell growth inhibitor and screening method thereof
#6592Influenza virus reassortment
#6593Methods for producing enteroendocrine cells that make and secrete insulin
#6594Pharmaceutical composition for transcolonic absorption
#6595Cancer therapy
#6596siRNA targeting myeloid differentiation primary response gene (88) (MYD88)
#6597Polypeptides having cellobiohydrolase activity and polynucleotides encoding same
#6598Microvesicles carrying small interfering RNAs, preparation methods and uses thereof
#6599Custom designed microbubble contrast agents and techniques of ultrasound delivery optimized for gene therapy
#6600Preparation of microvesicle-siRNA complexes and use thereof in AIDS treatment