Mammal with an orthotopic tumor capable of metastasis, a method of making and a method of using

METHODS AND COMPOSITIONS RELATED TO THE SMCHD1 GENE

Modified nucleosides, analogs thereof and oligomeric compounds prepared therefrom

Treatment of tumor suppressor gene related diseases by inhibition of natural antisense transcript to the gene

Compositions and methods for controlling arthropod parasite and pest infestations

Oligonucleotide compounds comprising non-nucleotide overhangs

METHODS OF TREATING OBESITY

Treatments of oxidative stress conditions

Generation of human induced pluripotent stem cells using nucleic acid sequences that inhibit Δ-NP63 and DGCR8

Skin lightening composition

Method for expression of small RNA molecules within a cell

Treatment of pyrroline-5-carboxylate reductase 1 (PYCR1) related diseases by inhibition of natural antisense transcript to PYCR1

HEXIM-1 AS A TARGET OF LEPTIN SIGNALING TO REGULATE OBESITY AND DIABETES

Treatment of filaggrin (FLG) related diseases by modulation of FLG expression and activity

Chemical modification of short small hairpin RNAs for inhibition of gene expression

siRNA compounds comprising terminal substitutions

THERAPIES FOR CANCER USING RLIP76

Modulation of TLR4-signaling pathway

Isoform of Bruton's Tyrosine Kinase (BTK) Protein

AEROSOL DELIVERY SYSTEMS, COMPOSITIONS AND METHODS

RNA interference mediated inhibition of gene expression using chemically modified short interfering nucleic acid (siNA)

NUCLEIC ACID COMPLEX AND NUCLEIC ACID-POLYSACCHARIDE COMPLEX

Sugar chain-containing polymer, and sugar chain-containing polymer complex

USP37 inactivation as a treatment for PLZF/RARA-associated acute promyelocytic leukemia

Methods and compositions for inhibiting the growth and/or proliferation of MYC-driven tumor cells

Constructs for diagnosing and treating inflammatory bowel diseases and colon cancer

Compositions and methods for controlling leptinotarsa

Ionizable cationic lipid for RNA delivery

Charge conversional ternary polyplex

RNA interference mediating small RNA molecules

Therapeutic targets for Alzheimer's disease

Methods of treating and diagnosing diseases using agents that regulate the alternative splicing pathway

Small molecule inhibitors of RNA binding motif (RBM) proteins for the treatment of acute cellular injury

Oligoribonucleotides and methods of use thereof for treatment of alopecia, acute renal failure and other diseases

Sustained release siRNA for ocular drug delivery

Method of diagnosing, treating and determining progression and survival of cancer cells using BCL-2 antagonist of cell death (BAD) pathway gene signature

Lipidated glycosaminoglycan particles for the delivery of nucleic acids

METHODS FOR DIAGNOSING AND TREATING FOCAL SEGMENTAL GLOMERULOSCLEROSIS

COMPOSITIONS AND METHODS FOR THE TREATMENT OF RADIATION EXPOSURE

USES OF CXCL17, A NOVEL CHEMOKINE MARKER OF HUMAN LUNG AND GASTROINTESTINAL DISEASE

Methods and Uses for Proprotein Convertase Subtilisin Kexin 9 (PCSK9) Inhibitors

Compositions and methods for the control of root lesion nematode

Compositions for controlling mites in bees

Treatment of RNASE H1 related diseases by inhibition of natural antisense transcript to RNASE H1

PYRUVATE DEHYROGENASE KINASES AS THERAEUTIC TARGETS FOR CANCER AND ISCHEMIC DISEASES

METHOD FOR DOWN-REGULATING GENE EXPRESSION IN FUNGI

Compositions and methods for inducing myoblast differentiation and myotube formation

Diester and triester based low molecular weight, biodegradeable cationic lipids for oligonucleotide delivery

High complexity siRNA pools

Method for rapidly evaluating performance of short interfering RNA with novel chemical modifications

Composition and methods for reduced scarring and treatment of fibrosis

METHODS OF MODULATING ANGIOGENESIS VIA TRPV4

TREATMENT OF CANCER

Transgenic plant-based methods for plant pests using RNAI

Combination therapy for treating hearing and balance disorders

Reducing galectin-12 activity to influence the cell function of human sebocytes

Modulation of sphingosine 1-phosphate metabolizing enzymes for the treatment of negative-strand RNA virus infections

Diagnosis of autism spectrum disorders and its treatment with an antagonist or inhibitor of the 5-HT2c receptor signaling pathway

AMPK activator screening method, and AMPK activator

Transferrin receptor aptamers and aptamer-targeted delivery

COLON DISEASE TARGETS AND USES THEREOF

Treatment of interferon regulatory factor 8 (IRF8) related diseases by inhibition of natural antisense transcript to IRF8

RNA products and uses thereof

CUL4B as predictive biomarker for cancer treatment

Influenza virus reassortment method

Method for constructing functional nucleic acid molecule, and nucleic acid combination to be used in said method

Methods for producing interfering RNA molecules in mammalian cells and therapeutic uses for such molecules

Lipid nanoparticle compositions and methods of making and methods of using the same

Methods and compositions for root knot nematode control

Compositions and Methods for Inhibiting Expression of RRM2 Genes

Method for treating glioma using Tarbp2 expression inhibitor

Inhibition of DNA2 in fanconi anemia

RNA-interference-inducing nucleic acid molecule able to penetrate into cells, and use therefor

Compositions and methods for decreasing leukocyte extravasation and vessel fluid leakage

Compositions and methods for silencing ebola virus gene expression

Compositions and methods for inhibiting expression of the ALAS1 gene

Cancer therapeutics

Composition for gene delivery

Compositions and methods for siRNA inhibition of angiogenesis

Methods and compositions for the specific inhibition of gene expression by double-stranded RNA

Interfering RNA molecules

Polynucleotide comprising sequences of wheat gliadins and use thereof for silencing by RNAi

Treatment of Paraoxonase 1 (PON1) related diseases by inhibition of natural antisense transcript to PON1

Multi-targeting short interfering RNAs

MEANS AND METHODS FOR THE SPECIFIC MODULATION OF TARGET GENES IN THE CNS AND THE EYE AND METHODS FOR THEIR IDENTIFICATION

Fidgetin-like 2 as a target to enhance wound healing

RNA INTERFERENCE MEDIATED INHIBITION OF GENE EXPRESSION USING CHEMICALLY MODIFIED SHORT INTERFERING NUCLEIC ACID (siNA)

Single-stranded nucleic acid molecule for regulating expression of gene having delivering function

LIM kinasemodulating agents for neurofibromatoses therapy and methods for screening for same

Compositions and methods for the treatment of VprBP-related cancers

GNAQ targeted dsRNA compositions and methods for inhibiting expression

Rational design of microRNA-siRNA chimeras for multi-functional target suppression

COMPOSITIONS AND METHODS FOR MODULATING MITOCHONDRIAL PYRUVATE CARRIER ACTIVITY

NOVEL THERAPEUTIC TARGET AND DIAGNOSTIC MARKER FOR ASTHMA AND RELATED CONDITIONS

Methods of Treating Hepatitis C Virus Infection

Method of regulating gene expression

RNA-interference by single-stranded RNA molecules

Treatment of hepatocyte growth factor (HGF) related diseases by inhibition of natural antisense transcript to HGF

Modulation of NLGn4 expression, NK cell activity in non-alcoholic fatty liver disease (NAFLD)

METHOD FOR TREATING CELL PROLIFERATIVE DISORDER BY INHIBITING C1GALT1 EXPRESSION

Block copolymer, liquid composite thereof, nucleic acid preparation, preparation methods therefor, and use thereof

METHOD OF CONTROLLING INITIAL DRUG RELEASE OF siRNA FROM SUSTAINED-RELEASE IMPLANTS

MICRORNA-BASED METHODS AND COMPOSITIONS FOR THE DIAGNOSIS, PROGNOSIS AND TREATMENT OF TUMOR INVOLVING CHROMOSOMAL REARRANGEMENTS

Micro-RNAs involved in macular degeneration

G protein-coupled purinergic receptor Gpr17 mediates orexigenic effects of FoxO1 in AgRP neurons

COMPOSITIONS AND METHODS FOR EFFICACIOUS AND SAFE DELIVERY OF siRNA USING SPECIFIC CHITOSAN-BASED NANOCOMPLEXES

Lipid-derived neutral nanoparticles

Cancer-related extracellular matrix signatures and related methods and products

Glycaspis Brimblecombei Control Agents

Bronze bug control agents

MULTI-TARGET MODULATION FOR TREATING FIBROSIS AND INFLAMMATORY CONDITIONS

Spalt-like transcription factor 4 (SALL4) and uses thereof

Reduction of formation of amidated amino acids in cell lines for protein expression

Method for selectively inhibiting ACAT1 in the treatment of neurodegenerative diseases

Method for treatment of diabetes by a small molecule inhibitor for GRK5

Agents and methods for treating and preventing seborrheic keratosis

ANTI-NEOPLASTIC USES OF ARTEMIN ANTAGONISTS

iRNA agents with biocleavable tethers

Micro-RMA inhibitor

Treatment of down syndrome gene related diseases by inhibition of natural antisense transcript to a down syndrome gene

Preventing or treating viral infection using an inhibitor of the LSD1 protein, a MAO inhibitor or an inhibitor of LSD1 and a MAO inhibitor

DELIVERY MOLECULES FOR THERAPEUTICS

NOVEL NTRK1 FUSION MOLECULES AND USES THEREOF

Methods and pharmaceutical compositions for the treatment of hypertension

BIOMARKERS FOR CANCER CHARACTERIZATION AND TREATMENT

Methods for genome-wide screening and construction of genetic interaction maps

Methods and kits for synthesis of siRNA expression cassettes

RNAi molecule delivery platform based on single-siRNA and shRNA nanocapsules

Use of annexin A3 as a diagnostic and prognostic biomarker and therapeutic target for treating hepatocellular carcinoma

LM-antibodies, functional fragments, LM-1 target antigen, and methods for making and using same

Combination therapy using c-Met inhibitor and beta-catenin inhibitor

EGFL7 targeting and/or binding polypeptides and methods for inhibiting angiogenesis

Compositions and methods for treating otitis media and other conditions with inhibitors of CYLD

METHODS FOR DELIVERY OF siRNA TO THE SPINAL CORD AND THERAPIES ARISING THEREFROM

Glycoconjugates of RNA interference agents

Methods for controlling pests using RNAi

THERAPEUTIC TARGETS FOR MITOCHONDRIAL DISORDERS

Methods and compositions for the specific inhibition of MCL1 by double-stranded RNA

Neurofibromatoses therapeutic agents and screening for same

Methods of treating cancer having an active Wnt/β-catenin pathway

Visfatin therapeutic agents for the treatment of acne and other conditions

REDUCING CUTANEOUS SCAR FORMATION AND TREATING SKIN CONDITIONS

METHOD FOR INHIBITING CELL GROWTH, NUCLEIC ACID MOLECULE HAVING RNA INTERFERENCE EFFECT ON NEK10 VARIANT GENE, AND ANTICANCER AGENT

Trialkyl cationic lipids and methods of use thereof

High molecular weight arginine-grafted bioreducible polymers

Methods and compositions for the specific inhibition of KRAS by asymmetric double-stranded RNA

RNAi-RELATED INHIBITION OF TNF alpha SIGNALING PATHWAY FOR TREATMENT OF GLAUCOMA

NOVEL FUSION GENES IDENTIFIED IN LUNG CANCER

USE OF INHIBITORS OF ZDHHC2 ACTIVITY FOR MODULATION OF ADIPOGENESIS

Double-stranded oligonucleotides

Methods for the treatment of nonalcoholic steatohepatitis

Cellular targets for HIV infection

HIGH THROUGHPUT METHODS FOR FUNCTIONALLY DETERMINING RNA INTERFERENCE EFFICIENCY

Methods of treating proliferative disorders with malate or derivatives thereof

Compositions of combinations of non-covalent DNA binding agents and anti-cancer and/or anti-inflammatory agents and their use in disease treatment

BRANCHED POLYMERS

Compositions and methods for insecticidal control of stinkbugs

Dually derivatized chitosan nanoparticles and methods of making and using the same

INHIBITORS OF NOX4 EXPRESSION AND /OR NOX4 FUNCTION AND THEIR USE IN THE PREVENTION AND TREATMENT OF NERVE INJURY AND/OR NEUROPATHIC PAIN

Reverse micelle system comprising nucleic acids and use thereof

Methods and compositions for RNAi-based cancer treatment

Methods for treating eye disorders

Methods for diagnosing and treating neuroendocrine cancer

Combination therapy for cancer using HSP27 inhibitor and EGFR tyrosine kinase inhibitors or anti-folates

Delivery of dsRNA to arthropods

RNA-directed DNA cleavage by the Cas9-crRNA complex

RNA Modulating Oligonucleotides with Improved Characteristics for the Treatment of Duchenne and Becker Muscular Dystrophy

Pain treatment

METHOD OF REGULATING CFTR EXPRESSION AND PROCESSING

Prostate cancer-specific alterations in ERG gene expression and detection and treatment methods based on those alterations

Compositions and Methods for Diagnosing, Preventing and Treating Intracranial Aneurysms

Method of enhancing the efficacy of anti-hepatocyte growth factor receptor breast cancer therapy by administering an inhibitor of mena

Compositions and methods for treating tumors, fibrosis, and pulmonary alveolar proteinosis

Compositions for Inhibiting Gene Expression and Uses Thereof

Extended dicer substrate agents and methods for the specific inhibition of gene expression

Extended dicer substrate agents and methods for the specific inhibition of gene expression

Pharmaceutical composition for preventing or treating diabetes containing TENC1 expression or activity suppressor

Nano delivery systems for siRNA

siRNA compositions and methods for inhibiting gene expression in tumor initiating cells of breast cancer

ROBO2 inhibitory compositions comprising SLIT2-binding extracellular domain of ROBO2

RNA-Mediated Gene Modulation

Anaplastic lymphoma kinase (ALK) as an oncogene capable of transforming normal human cells

Modulating the interaction between ZO-2/TJP2 and a Snail zinc finger transcription factor family member

Methods and compositions for neuroprotection

Nanoconjugates able to cross the blood-brain barrier

TREATMENT OF UTERINE LEIOMYOMATA

RHOGEF12 IS A THERAPEUTIC TARGET FOR THE TREATMENT OF HEART FAILURE

Vitamin B6-coupled poly(ester amine) as gene carrier and application in cancer gene therapy

Increasing taxane sensitivity in cancer cells

POLYPEPTIDES AND POLYNUCLEOTIDES FOR ARTEMIN AND RELATED LIGANDS, AND METHODS OF USE THEREOF

BACTERIAL MEDIATED THF ALPHA GENE SILENCING

Identification of molecular pathways and methods of use thereof for treating retinal neurodegeneration and other neurodegenerative disorders

Compositions and methods for the suppression of target polynucleotides from lepidoptera

Methods and Compositions for Modulating Gene Expression Using Oligonucleotide Based Drugs Administered in vivo or in vitro

Aptamer regulated nucleic acids and uses thereof

Pharmaceutical compositions for preventing or treating angiogenic diseases comprising inhibitors of NUP153 gene expression or NUP153 activity as active ingredient

Compositions and methods for diagnosing and treating hyperthyroidism in companion animals

Method for Preparing Fertility-Lowered Plant

Compositions and methods for the modulation of DNA damage responses using BAL1 and BBAP

CELL ADHESION INHIBITOR, CELL PROLIFERATION INHIBITOR, AND METHOD AND KIT FOR EXAMINING CANCER

Double-stranded and single-stranded RNA molecules with 5′ Triphosphates and their use for inducing interferon

Personalized medicine for the prediction of therapy targeting the hedgehog pathway

Arginine-based lipids for delivery of therapeutics

BACTERIAL MEDIATED THF ALPHA GENE SILENCING

EMT-INDUCING TRANSCRIPTION FACTORS COOPERATE WITH SOX9

NUCLEIC ACID MOLECULE FOR INHIBITING ACTIVITY OF RNAI MOLECULE

METHODS AND COMPOSITIONS FOR TREATING INSECTS

RNAi MODULATION OF RSV AND THERAPEUTIC USES THEREOF

Inhibition of the glycine cleavage system for treatment of cancer

Method for enhancing remyelination using GLI1 inhibitors

iRNA Agents Targeting VEGF

Methods and compositions for the specific inhibition of alpha-1 antitrypsin by double-stranded RNA

Compositions and methods to promote erythropoiesis

Single-Stranded Nucleic Acid Molecule for Controlling Gene Expression

Methods, kits, and systems for treatment of metastatic papillary thyroid cancer

Compositions and Methods for Suppressing Gene Expression of p53 and Clusterin

Cottonseed oil and uses

Use of human NLK gene and associated drugs thereof

ADAM12 inhibitors and their use against inflammation-induced fibrosis

High-efficiency nanoparticle-type double-helical oligo-RNA structure and method for preparing same

Methods and compositions for reducing viral genome amounts in a target cell

Lipid particle, nucleic acid transfer carrier, compound for manufacturing nucleic acid transfer carrier, method for manufacturing lipid particle, and gene transfer method

Novel shRNA Molecules and Methods of Use Thereof

Polypeptides having cellulolytic enhancing activity and polynucleotides encoding same

Methods and compositions involving miRNA and miRNA inhibitor molecules

METHODS AND COMPOSITIONS FOR INCREASING RNA INTERFERENCE

Simultaneous gene silencing and suppressing gene silencing in the same cell

Transgenic plants modified for reduced cadmium transport, derivative products, and related methods

Transcriptional repression leading to parkinson's disease

INHIBITION OF PATTERN RECOGNITION RECEPTORS IN PANCREATIC CANCER TREATMENT USING TLR INHIBITORS

Retinaldehyde mimetics and inhibitors of retinaldehyde dehydrogenase I in the treatment of disorders

Collateral gene inactivation biomarkers and targets for cancer therapy

DESIGN OF NUCLEIC ACID BINDING MOLECULES WITH NON-WATSON CRICK AND NON-CANONICAL PAIRING BASED ON ARTIFICIAL MUTATION CONSENSUS SEQUENCES TO COUNTER ESCAPE MUTATIONS

MATERIALS AND METHODS FOR TREATING PTEN MUTATED OR DEFICIENT CANCER

Agonists and antagonists of toll-like receptor (TLR) 13

Treatment of vasculoproliferative conditions with Lrg1 antagonists

Methods and compositions involving NKG2D inhibitors and cancer

Polypeptides having beta-xylosidase activity and polynucleotides encoding same

dsRNA as insect control agent

Method to trigger RNA interference

Double-stranded RNA compounds to CASP2 and uses thereof

Prevention and treatment of Nosema disease in bees

Methods and compositions to protect aquatic invertebrates from disease

Compositions and methods comprising histidyl-tRNA synthetase splice variants having non-canonical biological activities

Amine cationic lipids and uses thereof

RNA interference for the treatment of gain-of-function disorders

INHIBITION OF MACROPHAGE-SYNTHESIZED WNT7B TO INHIBIT TUMOR ANGIOGENESIS AND METASTASIS

Therapeutic nanoparticles and methods of use thereof

Screening method

Methods and compositions for the treatment of cancer

COMBINATION THERAPY FOR TREATING HEARING AND BALANCE DISORDERS

CDCP1 AND BREAST CANCER

Methods and compositions for the specific inhibition of gene expression by double-stranded RNA

RNAi-related inhibition of TNF alpha signaling pathway for treatment of ocular angiogenesis

RNAi-mediated inhibition of spleen tyrosine kinase-related inflammatory conditions

RNAi-mediated inhibition of tumor necrosis factor α-related conditions

Metabolic gene mesenchymal signatures and uses thereof

RNAi Inhibition of Serum Amyloid A For Treatment of Glaucoma

Method for treating fibrosis using siRNA and a retinoid-lipid drug carrier

COMPOSITIONS AND METHODS FOR TREATMENT OF METASTATIC CANCER

siRNA conjugate and preparation method thereof

Methods and compositions involving miRNA and miRNA inhibitor molecules

Peptide sequence design and use thereof for peptide-mediated siRNA delivery

Small interference RNAs, uses thereof and method for inhibiting the expression of plk1 gene

Amphipathic co-oligomers for the delivery of siRNA

Compositions and methods for inhibiting expression of the PCSK9 gene

Extended dicer substrate agents and methods for the specific inhibition of gene expression

Double-stranded nucleic acid molecule, cancer cell proliferation inhibitor and pharmaceutical agent suitable for prevention or treatment of cancer

Repressor on IFN-λ promoter and siRNA against ZEB1 and BLIMP-1 to increase IFN-λ gene activity

Serapina1 iRNA compositions and methods of use thereof

RTP801L SIRNA COMPOUNDS AND METHODS OF USE THEREOF

Feeder-free Derivation of human-induced pluripotent stem cells with synthetic messenger RNA

IN VIVO DELIVERY OF NUCLEIC ACIDS TO THE LIVER OR LIVER TISSUE

COMBINATORIAL METHODS AND COMPOSITIONS FOR TREATMENT OF MELANOMA

RNAi for the control of insects and arachnids

IN VIVO DELIVERY OF NUCLEIC ACIDS TO THE LIVER OR LIVER TISSUE

Method of treating and reducing the risk of acute myelogenous leukemia

RNA interference mediated inhibition of catenin (cadherin-associated protein), beta 1 (CTNNB1) gene expression using short interfering nucleic acid (SINA)

Oligonucleotides for RNA interference and biological applications thereof

Method for reducing expression of downregulated in renal cell carcinoma in malignant gliomas

Compositions and methods for inhibiting expression of factor VII gene

METHODS AND COMPOSITIONS FOR REDUCING ACTIVITY OF THE ATRIAL NATRIURETIC PEPTIDE RECEPTOR AND FOR TREATMENT OF DISEASES

Combined hairpin-antisense compositions and methods for modulating expression

METHODS AND COMPOSITIONS TO MODULATE ANTIVIRAL AND IMMUNE ACTIVITY RESPONSES

MCPIP as wound therapy

siRNA molecule for inhibiting growth of melanin and application thereof

Oligomeric compounds and compositions for use in modulation of small non-coding RNAs

Lipid Formulated Compositions and Methods for Inhibiting Expression of Eg5 and VEGF Genes

Methods of identifying and using MDM2 inhibitors

Therapeutic use of activators of zinc finger protein GL13

Compositions and methods for modulating an immune response

DELIVERY OF RNA INTERFERING AGENTS

NOVEL DOUBLE-STRANDED RIBONUCLEIC ACIDS WITH RUGGED PHYSICO-CHEMICAL STRUCTURE AND HIGHLY SPECIFIC BIOLOGIC ACTIVITY

Methods and pharmaceutical compositions for treating cancer

Culicinae mosquito Tra-2 RNA interference technique to genetically produce maleness population

Single-stranded nucleic acid molecule having amino acid backbone

Lipids, lipid complexes and use thereof

Oligomeric compounds and compositions for use in modulation of small non-coding RNAS

Exonuclease resistant polynucleotide and related duplex polynucleotides, constructs, compositions, methods and systems

Oligonucleotide modulators of the toll-like receptor pathway