109168 ⎘
Structure or type of the nucleic acid; Chemical structure of the backbone linked by 2'-5' linkages, i.e. having a free 3'-position
REVERSIR TM COMPOUNDS
#2TUNING CRISPR/CAS9 ACTIVITY WITH CHEMICALLY MODIFIED NUCLEOTIDE SUBSTITUTIONS
#3REVERSIR™ compounds
#4DIRECT OLIGONUCLEOTIDE SYNTHESIS ON CELLS AND BIOMOLECULES
#5REVERSIR TM COMPOUNDS
#6Methods for extending polynucleotides
#7Direct oligonucleotide synthesis on cells and biomolecules
#8siRNA sequence-independent modification formats for reducing off-target phenotypic effects in RNAI, and stabilized forms thereof
#9Treatment of collagen gene related diseases by inhibition of natural antisense transcript to a collagen gene
#10Tuning CRISPR/Cas9 activity with chemically modified nucleotide substitutions
#11Double-stranded oligonucleotide molecules targeting p53 and methods of use thereof
#12METHODS AND COMPOSITIONS FOR PREVENTING ISCHEMIA REPERFUSION INJURY IN ORGANS
#13Short interfering nucleic acid (siNA) molecules containing a 2′ internucleoside linkage (3dT)
#14siRNA sequence-independent modification formats for reducing off-target phenotypic effects in RNAi, and stabilized forms thereof
#15DOUBLE-STRANDED OLIGONUCLEOTIDE MOLECULES TO P53 AND METHODS OF USE THEREOF
#16Double-stranded oligonucleotide molecules to DDIT4 and methods of use thereof
#17Methods and compositions for preventing ischemia reperfusion injury in organs
#18METHODS AND COMPOSITIONS FOR PREVENTING ISCHEMIA REPERFUSION INJURY IN ORGANS
#19Double stranded oligonucleotide compounds comprising positional modifications
#20siRNA sequence-independent modification formats for reducing off-target phenotypic effects in RNAI, and stabilized forms thereof
#21Phosphorous-linked oligomeric compounds and their use in gene modulation
#22Short interfering nucleic acid (siNA) molecules containing a 2′ internucleoside linkage
#23RNAi-related inhibition of TNF-alpha signaling pathway for treatment of ocular angiogenesis
#24Double-stranded oligonucleotide molecules to DDIT4 and methods of use thereof
#25Double-stranded oligonucleotide molecules to P53 and methods of use thereof
#26RNAi-related inhibition of TNF alpha signaling pathway for treatment of ocular angiogenesis
#27Synthetic lariat RNA for RNA interference
#28SiRNA sequence-independent modification formats for reducing off-target phenotypic effects in RNAi, and stabilized forms thereof
#29RNAi sequence-independent modification formats, and stabilized forms thereof
#30LNA OLIGONUCLEOTIDES AND THE TREATMENT OF CANCER
#31TREATMENT OF COLLAGEN GENE RELATED DISEASES BY INHIBITION OF NATURAL ANTISENSE TRANSCRIPT TO A COLLAGEN GENE
#32RNAi-related inhibition of TNFα signaling pathway for treatment of ocular angiogenesis
#33RNAi-RELATED INHIBITION OF TNFa SIGNALING PATHWAY FOR TREATMENT OF MACULAR EDEMA
#34Potentiation of autoimmune and inflammatory disease treatments by immune regulatory oligonucleotide (IRO) antagonists of TLR7 and TLR9
#35Double-stranded RNA directed to CASP2 and methods of use thereof
#36siRNA compounds for inhibiting NRF2
#37NOVEL SIRNA STRUCTURES
#38RNAi-RELATED INHIBITION OF TNFa SIGNALING PATHWAY FOR TREATMENT OF OCULAR ANGIOGENESIS
#39siRNA sequence-independent modification formats for reducing off-target phenotypic effects in RNAi, and stabilized forms thereof
#405'-Substituted-2-F' Modified Nucleosides and Oligomeric Compounds Prepared Therefrom
#41Method of treating a cancer by administering A 2′,5′-oligoadenylate analog
#42COMPOSITIONS AND METHODS FOR SPECIFICALLY SILENCING A TARGET NUCLEIC ACID
#43Modified short interfering RNA
#44LNA oligonucleotides and the treatment of cancer
#45RNAi-RELATED INHIBITION OF TNFa SIGNALING PATHWAY FOR TREATMENT OF MACULAR EDEMA
#46RNAi-RELATED INHIBITION OF TNFalpha SIGNALING PATHWAY FOR TREATMENT OF OCULAR ANGIOGENESIS
#47LNA oligonucleotides and the treatment of cancer
#48Oligoribonucleotide derivatives for specific inhibition of gene expression
#492′, 5′-oligoadenylate analogs
#50Methods of preventing off-target gene silencing
#51Phosphorous-linked oligomeric compounds and their use in gene modulation