ClassID:

109170

C12N2310/321 - page 4 - CPC Classification

Classification description:

Structure or type of the nucleic acid; Chemical structure of the sugar 2'-O-R Modification

Recent Application in this class:
#901
20230167446
2023-06-01

COMPOUNDS AND METHODS FOR REDUCING PSD3 EXPRESSION

#902
20230165954
2023-06-01

RNA-BASED ADJUVANT TO ENHANCE THE IMMUNE RESPONSE TO VACCINES AND THERAPEUTICS

#903
20230159933
2023-05-25

COMPOSITIONS AND METHODS FOR SILENCING SCN9A EXPRESSION

#904
20230159926
2023-05-25

Base editing of PCSK9 and methods of using same for treatment of disease

#905
20230159925
2023-05-25

ANTISENSE OLIGONUCLEOTIDE OF CALM2

#906
20230159923
2023-05-25

RIG-I Agonists and Methods of Using Same

#907
20230159903
2023-05-25

Terminal Deoxynucleotidyl Transferase Variants and Uses Thereof

#908
20230158174
2023-05-25

CHEMICALLY MODIFIED GUIDE RNAS FOR GENOME EDITING WITH CAS9

#909
20230158059
2023-05-25

Prekallikrein-modulating compositions and methods of use thereof

#910
20230151365
2023-05-18

COMPOSITIONS AND METHODS FOR MODULATING TTR EXPRESSION

#911
20230151050
2023-05-18

ANTISENSE NUCLEIC ACIDS

#912
20230147979
2023-05-11

DESIGN METHOD FOR OPTIMIZED RIG-I LIGANDS

#913
20230147811
2023-05-11

MODULATORS OF GROWTH HORMONE RECEPTOR

#914
20230146956
2023-05-11

MULTIMERIC OLIGONUCLEOTIDES WITH DIVIDED STRANDS

#915
20230140670
2023-05-04

FORMULATIONS

#916
20230139594
2023-05-04

CATIONIC LIPIDS FOR LIPID NANOPARTICLE DELIVERY OF THERAPEUTICS TO HEPATIC STELLATE CELLS

#917
20230139322
2023-05-04

SiRNA molecule inhibiting the expression of the PCSK9 gene and use thereof

#918
20230138507
2023-05-04

ALPHA-2A ADRENERGIC RECEPTOR (ADRA2A) iRNA AGENT COMPOSITIONS AND METHODS OF USE THEREOF

#919
20230136552
2023-05-04

COMPLEMENT COMPONENT C5 iRNA COMPOSITIONS FOR USE IN THE TREATMENT OF AMYOTROPHIC LATERAL SCLEROSIS (ALS)

#920
20230134677
2023-05-04

ANTISENSE OLIGONUCLEOTIDES FOR USE IN THE TREATMENT OF USHER SYNDROME

#921
20230134582
2023-05-04

CHEMICALLY MODIFIED GUIDE RNAS FOR GENOME EDITING WITH CAS12B

#922
20230132756
2023-05-04

DOUBLE-STRANDED OLIGONUCLEOTIDE, COMPOSITION AND CONJUGATE COMPRISING DOUBLE-STRANDED OLIGONUCLEOTIDE, PREPARATION METHOD THEREOF AND USE THEREOF

#923
20230132602
2023-05-04

Targeted Inhibition Using Engineered Oligonucleotides

#924
20230132093
2023-04-27

EXTRACELLULAR VESICLE-NLRP3 ANTAGONIST

#925
20230127437
2023-04-27

ANTISENSE OLIGONUCLEOTIDE OF ATN1

#926
20230125933
2023-04-27

MANNAN BINDING LECTIN SERINE PEPTIDASE 2 (MASP2) IRNA COMPOSITIONS AND METHODS OF USE THEREOF

#927
20230125671
2023-04-27

RNAi Agents for Inhibiting Expression of Xanthine Dehydrogenase (XDH), Pharmaceutical Compositions Thereof, and Methods of Use

#928
20230125137
2023-04-27

UNC13A antisense oligonucleotides

#929
20230118592
2023-04-20

Compositions and methods for TTR gene editing and treating ATTR amyloidosis

#930
20230118177
2023-04-20

COMPOSITIONS AND METHODS FOR MODULATING GROWTH HORMONE RECEPTOR EXPRESSION

#931
20230116704
2023-04-13

ANTISENSE OLIGOMERS FOR TREATMENT OF CONDITIONS AND DISEASES

#932
20230114930
2023-04-13

Compounds and methods for reducing LRRK2 expression

#933
20230113863
2023-04-13

Selective Antisense Compounds and Uses Thereof

#934
20230112920
2023-04-13

Compositions for Modulating C9ORF72 Expression

#935
20230111150
2023-04-13

METHODS AND COMPOSITIONS FOR THE SPECIFIC INHIBITION OF KRAS BY ASYMMETRIC DOUBLE-STRANDED RNA

#936
20230109466
2023-04-06

Compositions for treatment of polycystic kidney disease

#937
20230108357
2023-04-06

Polymerizable compound, compound, and method for producing boranophosphate oligomer

#938
20230108340
2023-04-06

METHODS FOR REDUCING HTT EXPRESSION

#939
20230107967
2023-04-06

COMPOSITIONS AND METHODS FOR INHIBITING ALPHA-1 ANTITRYPSIN EXPRESSION

#940
20230107651
2023-04-06

METHODS OF TREATING SPINAL MUSCULAR ATROPHY

#941
20230105319
2023-04-06

PRODRUG INCORPORATED sgRNA SYNTHESIS

#942
20230104978
2023-04-06

RNA-Editing Oligonucleotides and Uses Thereof

#943
20230104708
2023-04-06

EXON SKIPPING COMPOSITIONS FOR TREATING MUSCULAR DYSTROPHY

#944
20230104125
2023-04-06

METHODS AND COMPOSITIONS FOR TREATING A PROPROTEIN CONVERTASE SUBTILISIN KEXIN (PCSK9) GENE-ASSOCIATED DISORDER

#945
20230098714
2023-03-30

MICRORNA COMPOSITIONS AND METHODS OF USE

#946
20230098111
2023-03-30

COMPOSITIONS AND METHODS TO TREAT NEUROLOGICAL DISEASES

#947
20230096557
2023-03-30

Exponential base-3 and greater nucleic acid amplification with reduced amplification time

#948
20230095566
2023-03-30

ANTI-ADAM33 OLIGONUCLEOTIDES AND RELATED METHODS

#949
20230092393
2023-03-23

Guide RNAs with chemical modification for prime editing

#950
20230091801
2023-03-23

Compositions and methods of treating facioscapulohumeral muscular dystrophy

#951
20230090531
2023-03-23

Compositions of matter for detection assays

#952
20230089915
2023-03-23

PRODUCTS AND COMPOSITIONS

#953
20230081388
2023-03-16

ANTISENSE OLIGOMERS AND METHODS FOR TREATING PARKIN-RELATED PATHOLOGIES

#954
20230078622
2023-03-16

Optimized anti-FLT1 oligonucleotide compounds for treatment of preeclampsia and other angiogenic disorders

#955
20230078200
2023-03-16

RNAi CONSTRUCTS AND METHODS FOR INHIBITING LPA EXPRESSION

#956
20230069235
2023-03-02

METHODS AND COMPOSITIONS FOR THE SPECIFIC INHIBITION OF ALPHA-1 ANTITRYPSIN BY DOUBLE-STRANDED RNA

#957
20230068672
2023-03-02

Oligonucleotides for the treatment of nucleotide repeat expansion disorders associated with MSH3 activity

#958
20230068339
2023-03-02

APOLIPOPROTEIN C3 (APOC3) iRNA COMPOSITIONS AND METHODS OF USE THEREOF

#959
20230066380
2023-03-02

ANTAGONISM AS A THERAPY FOR TDP-43 PROTEINOPATHIES

#960
20230063394
2023-03-02

ANTISENSE MOLECULES AND METHODS FOR TREATING PATHOLOGIES

#961
20230061751
2023-03-02

UNIVERSAL DYNAMIC PHARMACOKINETIC-MODIFYING ANCHORS

#962
20230060517
2023-03-02

NEW METHOD FOR TARGETED EDITING OF RNA

#963
20230059865
2023-02-23

Methods and compositions for modulating splicing

#964
20230058834
2023-02-23

Methods and compositions for the specific inhibition of transthyretin (TTR) by double-stranded RNA

#965
20230057718
2023-02-23

Compositions and methods for modulating complement factor B expression

#966
20230056569
2023-02-23

ATAXIN3 (ATXN3) RNAI AGENT COMPOSITIONS AND METHODS OF USE THEREOF

#967
20230055405
2023-02-23

COMPOUNDS AND METHODS FOR REDUCING APP EXPRESSION

#968
20230054178
2023-02-23

TREM compositions and uses thereof

#969
20230053332
2023-02-23

COMPOSITIONS AND METHODS FOR INHIBITING EXPRESSION OF MUTANT EGFR GENE

#970
20230049529
2023-02-16

MODIFIED DOUBLE STRANDED OLIGONUCLEOTIDE

#971
20230047776
2023-02-16

Polynucleotide compositions and methods for gene expression regulations

#972
20230044994
2023-02-09

Compositions and Methods Comprising a TTR Guide RNA and a Polynucleotide Encoding an RNA-Guided DNA Binding Agent

#973
20230042451
2023-02-09

Compositions and methods for inhibiting mitochondria amidoxime reducing component 1 (MARC1) expression

#974
20230040829
2023-02-09

COMPOSITIONS AND METHODS FOR MODULATING ATAXIN 3 EXPRESSION

#975
20230032974
2023-02-02

SMALL RIBOSOMAL PROTEIN SUBUNIT 25 (RPS25) iRNA AGENT COMPOSITIONS AND METHODS OF USE THEREOF

#976
20230032846
2023-02-02

SYSTEMS AND METHODS FOR LIPID NANOPARTICLE DELIVERY OF GENE EDITING MACHINERY

#977
20230030119
2023-02-02

RNA INTERFERENCE MEDIATED INHIBITION OF CATENIN (CADHERIN-ASSOCIATED PROTEIN), BETA 1 (CTNNB1) GENE EXPRESSION USING SHORT INTERFERING NUCLEIC ACID (SINA)

#978
20230028937
2023-01-26

MicroRNA (miRNA) and Downstream Targets for Diagnostic and Therapeutic Purposes

#979
20230027209
2023-01-26

Implantable Medical Device for the Delivery of a Nucleic Acid

#980
20230026968
2023-01-26

COMPOSITIONS AND METHODS FOR INHIBITING EXPRESSION OF THE ALAS1 GENE

#981
20230023015
2023-01-26

Modulation of huntingtin expression

#982
20230021431
2023-01-26

Oligonucleotides for SARS-CoV-2 modulation

#983
20230018254
2023-01-19

EXTRACELLULAR VESICLES WITH ANTISENSE OLIGONUCLEOTIDES TARGETING KRAS

#984
20230015481
2023-01-19

Modulators and modulation of the receptor for advanced glycation end-products RNA

#985
20230013224
2023-01-19

RNAi agents for inhibiting expression of xanthine dehydrogenase (XDH), pharmaceutical compositions thereof, and methods of use

#986
20230013022
2023-01-19

RNAi Agents for Inhibiting Expression of Beta-ENaC, Compositions Thereof, and Methods of Use

#987
20230010288
2023-01-12

RNAI AGENTS, COMPOSITIONS AND METHODS OF USE THEREOF FOR TREATING TRANSTHYRETIN (TTR) ASSOCIATED DISEASES

#988
20230002772
2023-01-05

PCSK9 iRNA COMPOSITIONS AND METHODS OF USE THEREOF

#989
20230002771
2023-01-05

Compounds and methods for modulating factor XII

#990
20230002768
2023-01-05

Compositions and methods for inhibiting gene expression of alpha-1 antitrypsin

#991
20230002767
2023-01-05

RNAi Agents for Inhibiting Expression of Mucin 5AC (MUC5AC), Compositions Thereof, and Methods of Use

#992
20230002766
2023-01-05

CHEMICALLY MODIFIED OLIGONUCLEOTIDES TARGETING BROMODOMAIN CONTAINING PROTEIN 4 (BRD4) FOR IMMUNOTHERAPY

#993
20230000895
2023-01-05

METHODS FOR TREATING HEPATITIS B INFECTION

#994
20220411804
2022-12-29

PIKFYVE antisense oligonucleotides

#995
20220411800
2022-12-29

RNA MOLECULE, CHIMERIC NA MOLECULE, DOUBLE-STRANDED RNA MOLECULE, AND DOUBLE-STRANDED CHIMERIC NA MOLECULE

#996
20220411797
2022-12-29

Twist signaling inhibitor compositions and methods of using the same

#997
20220411796
2022-12-29

COMPOSITIONS AND METHODS FOR DECREASING TAU EXPRESSION

#998
20220411793
2022-12-29

Compounds and methods for modulating UBE3A-ATS

#999
20220409735
2022-12-29

Compositions and methods of treating muscle dystrophy

#1000
20220403393
2022-12-22

Modulation of Angiopoietin-Like 3 Expression

#1001
20220403387
2022-12-22

MODULATING GENOMIC COMPLEXES

#1002
20220403386
2022-12-22

Selective reduction of allelic variants

#1003
20220403383
2022-12-22

METHODS AND COMPOSITIONS FOR MODULATING SPLICING

#1004
20220403382
2022-12-22

COMPOSITIONS AND METHODS FOR INHIBITING EXPRESSION OF THE ALAS1 GENE

#1005
20220403381
2022-12-22

COMPLEMENT COMPONENT C5 IRNA COMPOSITIONS AND METHODS OF USE THEREOF

#1006
20220403377
2022-12-22

MODIFIED iRNA AGENTS

#1007
20220396793
2022-12-15

Methods and compositions for the specific inhibition of alpha-1 antitrypsin by double-stranded RNA

#1008
20220395554
2022-12-15

LAG3 binding peptides

#1009
20220389432
2022-12-08

Allele-specific silencing therapy for DFNA9 using antisense oligonucleotides

#1010
20220389430
2022-12-08

CHEMICAL MODIFICATIONS OF SMALL INTERFERING RNA WITH MINIMAL FLUORINE CONTENT

#1011
20220389428
2022-12-08

Nucleic acid, composition and conjugate comprising the same, and preparation method and use thereof

#1012
20220389421
2022-12-08

RNA MODULATING OLIGONUCLEOTIDES WITH IMPROVED CHARACTERISTICS FOR THE TREATMENT OF NEUROMUSCULAR DISORDERS

#1013
20220387600
2022-12-08

CONJUGATES AND METHODS FOR TREATING LIVER FIBROSIS

#1014
20220380775
2022-12-01

Organic compositions to treat HSF1-related diseases

#1015
20220380774
2022-12-01

ASYMMETRIC SIRNA INHIBITING EXPRESSION OF PD-1

#1016
20220380773
2022-12-01

COMPOUNDS AND METHODS FOR REDUCING APP EXPRESSION

#1017
20220380772
2022-12-01

RNA interference mediated inhibition of prolyl hydroxylase domain 2 (PHD2) gene expression using short interfering nucleic acid (siNA)

#1018
20220380771
2022-12-01

Xanthine dehydrogenase (XDH) iRNA compositions and methods of use thereof

#1019
20220380770
2022-12-01

SHORT INTERFERING NUCLEIC ACID (siNA) MOLECULES AND USES THEREOF FOR CORONAVIRUS DISEASES

#1020
20220372488
2022-11-24

COMPOSITIONS AND METHODS FOR TREATING NEURODEGENERATIVE DISORDERS

#1021
20220372482
2022-11-24

Modified antisense oligonucleotide for inhibition of FoxP3 expression

#1022
20220372476
2022-11-24

Dynamic pharmacokinetic-modifying anchors

#1023
20220372475
2022-11-24

Inhibitors Of RNA Editing And Uses Thereof

#1024
20220370626
2022-11-24

FN3 domain-siRNA conjugates and uses thereof

#1025
20220364100
2022-11-17

OLIGONUCLEOTIDE COMPOUNDS FOR TREATMENT OF PREECLAMPSIA AND OTHER ANGIOGENIC DISORDERS

#1026
20220364098
2022-11-17

Compositions and methods for modulating PNPLA3 expression

#1027
20220364097
2022-11-17

RNAi-MEDIATED INHIBITION OF HIF1A FOR TREATMENT OF OCULAR ANGIOGENESIS

#1028
20220364096
2022-11-17

Modified Short Interfering Nucleic Acid (siNA) Molecules and Uses Thereof

#1029
20220364088
2022-11-17

COMPLEMENT COMPONENT C3 IRNA COMPOSITIONS AND METHODS OF USE THEREOF

#1030
20220364086
2022-11-17

ANTISENSE OLIGONUCLEOTIDE CAPABLE OF ALTERING SPLICING OF DUX4 pre-mRNA

#1031
20220348926
2022-11-03

PATATIN-LIKE PHOSPHOLIPASE DOMAIN CONTAINING 3 (PNPLA3) iRNA COMPOSITIONS AND METHODS OF USE THEREOF

#1032
20220348916
2022-11-03

COMPOSITION FOR DIAGNOSIS OR TREATMENT OF A CONDITION ASSOCIATED WITH INCREASED ACTIVITY OF EIF4E COMPRISING AN EIF4E INHIBITOR

#1033
20220348915
2022-11-03

GNAQ targeted dsRNA compositions and methods for inhibiting expression

#1034
20220340909
2022-10-27

COMPOSITIONS AND METHODS FOR INHIBITING KETOHEXOKINASE (KHK)

#1035
20220340907
2022-10-27

OLIGONUCLEOTIDES FOR TREATMENT OF ANGIOPOIETIN LIKE 4 (ANGPTL4) RELATED DISEASES

#1036
20220340900
2022-10-27

CHEMICALLY MODIFIED OLIGONUCLEOTIDES FOR RNA EDITING

#1037
20220333112
2022-10-20

Antisense nucleic acid that induces skipping of exon 50

#1038
20220333104
2022-10-20

TRANSTHYRETIN (TTR) iRNA COMPOSITIONS AND METHODS OF USE THEREOF FOR TREATING OR PREVENTING TTR-ASSOCIATED OCULAR DISEASES

#1039
20220331446
2022-10-20

Modified RNAi agents

#1040
20220331351
2022-10-20

Nucleic acids for inhibiting expression of TMPRSS6 and iron chelators

#1041
20220325300
2022-10-13

Methods and systems for guide RNA design and use

#1042
20220325280
2022-10-13

ANTISENSE OLIGONUCLEOTIDES AND THEIR USE FOR TREATING PENDRED SYNDROME

#1043
20220324984
2022-10-13

NUCLEIC ACID-POLYPEPTIDE COMPOSITIONS AND USES THEREOF

#1044
20220324900
2022-10-13

COMPOSITIONS AND METHODS FOR MODULATING ANGIOPOIETIN-LIKE 3 EXPRESSION

#1045
20220307027
2022-09-29

RNA-Editing Enzyme-Recruiting Oligonucleotides and Uses Thereof

#1046
20220307024
2022-09-29

DELIVERY OF OLIGONUCLEOTIDES TO THE STRIATUM

#1047
20220307023
2022-09-29

ANTISENSE RNA EDITING OLIGONUCLEOTIDES COMPRISING CYTIDINE ANALOGS

#1048
20220307022
2022-09-29

RNAI CONSTRUCTS FOR INHIBITING SCAP EXPRESSION AND METHODS OF USE THEREOF

#1049
20220307019
2022-09-29

DOUBLE-STRANDED NUCLEIC ACID COMPLEX AND USE THEREOF

#1050
20220296631
2022-09-22

METHODS FOR TREATING MUSCULAR DYSTROPHY USING INHIBITORY OLIGONUCLEOTIDES TO CD49D

#1051
20220296628
2022-09-22

RNA COMBINATIONS AND COMPOSITIONS WITH DECREASED IMMUNOSTIMULATORY PROPERTIES

#1052
20220290150
2022-09-15

Methods and compositions for modulating gene expression using oligonucleotide based drugs administered in vivo or in vitro

#1053
20220290148
2022-09-15

Defined multi-conjugates oligonucleotides

#1054
20220290143
2022-09-15

Products and compositions

#1055
20220290142
2022-09-15

COMPOSITIONS AND METHODS FOR MODULATING SPLICING AND PROTEIN EXPRESSION

#1056
20220282249
2022-09-08

COMPOUNDS AND METHODS USEFUL FOR MODULATING GENE SPLICING

#1057
20220282246
2022-09-08

OLIGONUCLEOTIDE THERAPY FOR STARGARDT DISEASE

#1058
20220275375
2022-09-01

COMPOSITIONS AND METHODS FOR THE TREATMENT OF HYPERCHOLESTEROLEMIA

#1059
20220275373
2022-09-01

METHODS AND COMPOSITIONS FOR TREATING MALIGNANT TUMORS ASSOCIATED WITH KRAS MUTATION

#1060
20220275366
2022-09-01

RNA INTERFERENCE MEDIATED INHIBITION OF GENE EXPRESSION USING CHEMICALLY MODIFIED SHORT INTERFERING NUCLEIC ACID (SINA)

#1061
20220275365
2022-09-01

COMPOSITIONS AND METHODS FOR MODULATING TTR EXPRESSION

#1062
20220267779
2022-08-25

SiRNA structures for high activity and reduced off target

#1063
20220267775
2022-08-25

CANCER TREATMENT USING TARGETED siRNA PHARMACEUTICAL FORMULATIONS TO DOWNREGULATE EXPRESSION OF PRDM14 PROTEIN

#1064
20220267770
2022-08-25

COMPOSITIONS AND METHODS OF USING C/EBP ALPHA SARNA

#1065
20220265864
2022-08-25

SPLICE MODULATING OLIGONUCLEOTIDES TARGETING RECEPTOR FOR ADVANCED GLYCATION END PRODUCTS AND METHODS OF USE

#1066
20220259600
2022-08-18

COMPOUNDS AND METHODS FOR MODULATING TMPRSS6 EXPRESSION

#1067
20220259592
2022-08-18

EXON SKIPPING COMPOSITIONS FOR TREATING MUSCULAR DYSTROPHY

#1068
20220251570
2022-08-11

COMPOSITIONS AND METHODS FOR INHIBITING EXPRESSION OF TMPRSS6 GENE

#1069
20220251555
2022-08-11

O-methyl rich fully stabilized oligonucleotides

#1070
20220251553
2022-08-11

Methods and compositions for inhibiting PMP22 expression

#1071
20220243209
2022-08-04

Modulators of Complement Factor B

#1072
20220243205
2022-08-04

Modulators of MALAT1 expression

#1073
20220243202
2022-08-04

NUCLEIC ACIDS FOR INHIBITING EXPRESSION OF PROS1 IN A CELL

#1074
20220243200
2022-08-04

COMPOSITIONS AND METHODS FOR MODULATING TAU EXPRESSION

#1075
20220243199
2022-08-04

Lipid formulated compositions and methods for inhibiting expression of serum amyloid a gene

#1076
20220235361
2022-07-28

RNAi Inhibition of Alpha-ENaC Expression

#1077
20220235358
2022-07-28

Angiopoietin-like 3 (ANGPTL3) iRNA compositions and methods of use thereof

#1078
20220235355
2022-07-28

Antisense oligonucleotides for the treatment of Leber congenital amaurosis

#1079
20220233714
2022-07-28

NANOGOLD-DNA BIOCONJUGATES AND METHODS OF USE THEREOF

#1080
20220233573
2022-07-28

METHODS AND COMPOSITIONS FOR TREATING PULMONARY ARTERIAL HYPTERNSION

#1081
20220228151
2022-07-21

Carboxypeptidase B2 (CPB2) iRNA COMPOSITIONS AND METHODS OF USE THEREOF

#1082
20220228149
2022-07-21

Methods and compositions for the specific inhibition of alpha-1 antitrypsin by double-stranded RNA

#1083
20220228144
2022-07-21

SERPIN FAMILY F MEMBER 2 (SERPINF2) iRNA COMPOSITIONS AND METHODS OF USE THEREOF

#1084
20220228140
2022-07-21

COMPOUND, METHOD AND PHARMACEUTICAL COMPOSITION FOR MODULATING EXPRESSION OF DUX4

#1085
20220213486
2022-07-07

COMPLEMENT COMPONENT iRNA COMPOSITIONS AND METHODS OF USE THEREOF

#1086
20220213485
2022-07-07

Nucleic acids and methods for the treatment of Pompe disease

#1087
20220213480
2022-07-07

Targeted inhibition using engineered oligonucleotides

#1088
20220213476
2022-07-07

Oral delivery of antisense conjugates targeting PCSK9

#1089
20220213475
2022-07-07

DUAL TARGETING siRNA AGENTS

#1090
20220213474
2022-07-07

MODULATION OF TRANSTHYRETIN EXPRESSION

#1091
20220213473
2022-07-07

COMPOSITIONS AND METHODS FOR INHIBITING EXPRESSION OF THE LECT2 GENE

#1092
20220213472
2022-07-07

MODULATION OF APOLIPOPROTEIN C-III (APOCIII) EXPRESSION IN LIPOPROTEIN LIPASE DEFICIENT (LPLD) POPULATIONS

#1093
20220204972
2022-06-30

Antisense oligonucleotides for the treatment of Stargardt disease

#1094
20220202847
2022-06-30

HIGH DENSITY LIPOPROTEIN BINDING PROTEIN (HDLBP/VIGILIN) iRNA COMPOSITIONS AND METHODS OF USE THEREOF

#1095
20220195439
2022-06-23

TREATMENT OF GLIAL CELL DERIVED NEUROTROPHIC FACTOR (GDNF) RELATED DISEASES BY INHIBITION OF NATURAL ANTISENSE TRANSCRIPT TO GDNF

#1096
20220195438
2022-06-23

OLIGOMERS

#1097
20220195437
2022-06-23

TAU-TARGETING OLIGONUCLEOTIDE GAPMERS

#1098
20220195435
2022-06-23

Antisense oligonucleotide and double stranded RNAS for control of hemipteran and lepidopteran pests

#1099
20220195433
2022-06-23

RNA interference mediated inhibition of gene expression using short interfering nucleic acids (siNA)

#1100
20220195430
2022-06-23

Compositions for modulating Ataxin 2 expression

#1101
20220195429
2022-06-23

OLIGONUCLEOTIDE COMPOSITIONS AND METHODS THEREOF

#1102
20220195427
2022-06-23

Compositions comprising chemically modified guide RNAs for CRISPR/Cas-mediated editing of HBB

#1103
20220195426
2022-06-23

CHEMICALLY MODIFIED GUIDE RNAS FOR CRISPR/CAS-MEDIATED GENE CORRECTION

#1104
20220195425
2022-06-23

Chemically modified guide RNAS for CRISPR/Cas-mediated gene regulation

#1105
20220186229
2022-06-16

METHODS AND COMPOSITIONS FOR INHIBITING EXPRESSION OF CYP27A1

#1106
20220186222
2022-06-16

Linkage modified oligomeric compounds and uses thereof

#1107
20220186217
2022-06-16

OLIGONUCLEOTIDE COMPOSITIONS AND METHODS THEREOF

#1108
20220184112
2022-06-16

COMPOSITIONS AND METHODS FOR ENHANCED INTESTINAL ABSORPTION OF CONJUGATED OLIGOMERIC COMPOUNDS

#1109
20220177893
2022-06-09

COMPOUNDS AND METHODS FOR REDUCING KCNT1 EXPRESSION

#1110
20220177888
2022-06-09

Modified short interfering nucleic acid (siNA) molecules and uses thereof

#1111
20220177884
2022-06-09

Oligonucleotides for modulating Tau expression

#1112
20220177883
2022-06-09

Antisense Oligonucleotides Targeting ATXN3

#1113
20220175813
2022-06-09

Methods for treating or preventing ophthalmological conditions

#1114
20220170025
2022-06-02

COMPOSITIONS AND METHODS FOR INHIBITING GENE EXPRESSION IN THE CENTRAL NERVOUS SYSTEM

#1115
20220170024
2022-06-02

ANTISENSE-INDUCED EXON2 INCLUSION IN ACID ALPHA-GLUCOSIDASE

#1116
20220170023
2022-06-02

Modulation of prekallikrein (PKK) expression

#1117
20220170016
2022-06-02

Nucleic acids for inhibiting expression of LPA in a cell

#1118
20220170015
2022-06-02

Alpha-1 antitrypsin (AAT) RNAi agents, compositions including AAT RNAi agents, and methods of use

#1119
20220162614
2022-05-26

RNAi-MEDIATED INHIBITION OF HIF1A FOR TREATMENT OF OCULAR ANGIOGENESIS

#1120
20220162607
2022-05-26

NUCLEIC ACID COMPLEX FOR MODULATING IHH EXPRESSION

#1121
20220162605
2022-05-26

ANTISENSE OLIGOMERS FOR TREATMENT OF CONDITIONS AND DISEASES

#1122
20220162604
2022-05-26

ANTISENSE NUCLEIC ACIDS

#1123
20220162603
2022-05-26

COMPOSITIONS COMPRISING ALTERNATING 2'-MODIFIED NUCLEOSIDES FOR USE IN GENE MODULATION

#1124
20220162598
2022-05-26

OLIGONUCLEOTIDE COMPOSITIONS AND METHODS THEREOF

#1125
20220155716
2022-05-19

SERPINA1 SIRNAS: COMPOSITIONS OF MATTER AND METHODS OF TREATMENT

#1126
20220154185
2022-05-19

HETERO DOUBLE-STRANDED antimiR

#1127
20220154182
2022-05-19

ANTISENSE OLIGONUCLEOTIDE-BASED PROGRANULIN AUGMENTATION THERAPY IN NEURODEGENERATIVE DISEASES

#1128
20220146496
2022-05-12

Oligonucleotides for inducing paternal UBE3A expression

#1129
20220145302
2022-05-12

TARGETS AND METHODS FOR TREATING EPSTEIN-BARR VIRUS MEDIATED NEURODEGENERATION

#1130
20220145295
2022-05-12

ENZYMATIC RNA SYNTHESIS

#1131
20220127618
2022-04-28

KETOHEXOKINASE (KHK) iRNA COMPOSITIONS AND METHODS OF USE THEREOF

#1132
20220127615
2022-04-28

CORONAVIRUS IRNA COMPOSITIONS AND METHODS OF USE THEREOF

#1133
20220127614
2022-04-28

Compositions and methods for treating COVID-19

#1134
20220127611
2022-04-28

Methods of modulating RNA translation

#1135
20220127610
2022-04-28

OLIGONUCLEOTIDES FOR USE IN THE TREATMENT OF DYSTROPHIC EPIDERMOLYSIS BULLOSA

#1136
20220127609
2022-04-28

ANTISENSE OLIGONUCLEOTIDES FOR NUCLEIC ACID EDITING

#1137
20220119820
2022-04-21

COMPOSITIONS AND METHODS FOR CORRECTING LIMB GIRDLE MUSCULAR DYSTROPHY TYPE 2C USING EXON SKIPPING

#1138
20220119817
2022-04-21

Polycomb-associated Non-Coding RNAs

#1139
20220119341
2022-04-21

Modified amine lipids

#1140
20220118000
2022-04-21

ANTISENSE OLIGOMERS AND USES THEREOF

#1141
20220117999
2022-04-21

PATATIN-LIKE PHOSPHOLIPASE DOMAIN CONTAINING 3 (PNPLA3) iRNA COMPOSITIONS AND METHODS OF USE THEREOF

#1142
20220112505
2022-04-14

RNAi Inhibition of Alpha-ENaC Expression

#1143
20220112503
2022-04-14

COMPOUNDS AND METHODS FOR REDUCING PMP22 EXPRESSION

#1144
20220112502
2022-04-14

Modulation of GYS1 expression

#1145
20220112497
2022-04-14

CANCER-SPECIFIC MOLECULES AND METHODS OF USE THEREOF

#1146
20220112496
2022-04-14

Therapeutic compositions for treating pain via multiple targets

#1147
20220112493
2022-04-14

PHOSPHONOACETATE GAPMER OLIGONUCLEOTIDES

#1148
20220106601
2022-04-07

Antisense Drug Against the Human Intercellular Adhesion Molecule 1 (ICAM-1)

#1149
20220098596
2022-03-31

SPLICE MODULATING OLIGONUCLEOTIDES AND METHODS OF USE THEREOF

#1150
20220098587
2022-03-31

Methods and compositions for editing RNAs

#1151
20220098586
2022-03-31

OLIGONUCLEOTIDE

#1152
20220098585
2022-03-31

OLIGONUCLEOTIDE COMPOSITIONS AND METHODS THEREOF

#1153
20220098582
2022-03-31

Methods for Treatment of Alport Syndrome

#1154
20220090087
2022-03-24

ANTISENSE OLIGONUCLEOTIDES TARGETING SCN2A RETAINED INTRONS

#1155
20220090082
2022-03-24

Gapmer antisense oligonucleotides targeting SARS-CoV-2 for treating COVID 19

#1156
20220090081
2022-03-24

NOVEL DNA APTAMER AND USE THEREOF

#1157
20220090080
2022-03-24

Method for generating aptamers with improved off-rates

#1158
20220090074
2022-03-24

HNF4a saRNA compositions and methods of use

#1159
20220090072
2022-03-24

Method of treating fatty liver disease

#1160
20220090069
2022-03-24

OLIGONUCLEOTIDES FOR HTT-1A MODULATION

#1161
20220090068
2022-03-24

Complement component C5 iRNA compositions and methods of use thereof

#1162
20220090067
2022-03-24

Products and compositions

#1163
20220090012
2022-03-24

GENETICALLY ENGINEERED T CELLS WITH REGNASE-1 AND/OR TGFBRII DISRUPTION HAVE IMPROVED FUNCTIONALITY AND PERSISTENCE

#1164
20220088078
2022-03-24

Genetically engineered T cells with regnase-1 and/or TGFBRII disruption have improved functionality and persistence

#1165
20220088077
2022-03-24

Genetically engineered t cells with Regnase-1 and/or TGFBRII disruption have improved functionality and persistence

#1166
20220081689
2022-03-17

Compounds and Methods for Use in Dystrophin Transcript

#1167
20220079973
2022-03-17

RNAi agents for Hepatitis B virus infection

#1168
20220073930
2022-03-10

COMPOSITIONS AND METHODS FOR TREATING AND PREVENTING AMYOTROPHIC LATERAL SCLEROSIS

#1169
20220073929
2022-03-10

Angiopoietin-like 3 (ANGPTL3) iRNA compositions and methods of use thereof

#1170
20220073928
2022-03-10

Angiopoietin-like 3 (ANGPTL3) iRNA compositions and methods of use thereof

#1171
20220073927
2022-03-10

Angiopoietin-like 3 (ANGPTL3) iRNA compositions and methods of use thereof

#1172
20220073926
2022-03-10

Angiopoietin-like 3 (ANGPTL3) iRNA compositions and methods of use thereof

#1173
20220073925
2022-03-10

Angiopoietin-like 3 (ANGPTL3) iRNA compositions and methods of use thereof

#1174
20220073924
2022-03-10

Angiopoietin-like 3 (ANGPTL3) iRNA compositions and methods of use thereof

#1175
20220073922
2022-03-10

Aptamers and use thereof

#1176
20220073918
2022-03-10

Allele selective inhibition of mutant C9orf72 foci expression by duplex RNAs targeting the expanded hexanucleotide repeat

#1177
20220073915
2022-03-10

ARTIFICIAL NUCLEIC ACIDS FOR RNA EDITING

#1178
20220073914
2022-03-10

COMPOUNDS AND METHODS FOR MODULATION OF SMN2

#1179
20220073913
2022-03-10

METHODS AND COMPOSITIONS FOR MODULATING ALPHA-1-ANTITRYPSIN EXPRESSION

#1180
20220072029
2022-03-10

Bi specific aptamer

#1181
20220072024
2022-03-10

COMPOSITIONS AND METHODS FOR INHIBITING HMGB1 EXPRESSION

#1182
20220064650
2022-03-03

MODULATION OF HEPATITIS B VIRUS (HBV) EXPRESSION

#1183
20220064645
2022-03-03

Double-stranded RNA molecule targeting CKIP-1 and use thereof

#1184
20220064638
2022-03-03

COMPOUNDS AND METHODS FOR MODULATING SMN2

#1185
20220056454
2022-02-24

RNAi Agents for Inhibiting Expression of 17beta-HSD Type 13 (HSD17B13), Compositions Thereof, and Methods of Use

#1186
20220056451
2022-02-24

HBV BINDING OLIGONUCLEOTIDES AND METHODS OF USE

#1187
20220056444
2022-02-24

PROCESS TO INHIBIT OR ELIMINATE EOSINOPHILIC DISEASES OF THE AIRWAY AND RELATED CONDITIONS

#1188
20220056443
2022-02-24

METABOLIC BENEFITS OF SHORT MIR-22 MIRNA ANTAGOMIR THERAPIES

#1189
20220056437
2022-02-24

METHODS AND COMPOSITIONS FOR INHIBITION OF CRISPR RE-CLEAVAGE EVENTS

#1190
20220056436
2022-02-24

Stabilized CRISPR complexes

#1191
20220054526
2022-02-24

Antisense compounds targeting genes associated with cystic fibrosis

#1192
20220049255
2022-02-17

Modulating the cellular stress response

#1193
20220049253
2022-02-17

COMPOSITIONS AND METHODS FOR INHIBITION OF EXPRESSION OF APOLIPOPROTEIN C-III (APOC3) GENES

#1194
20220049252
2022-02-17

CHEMICALLY-MODIFIED RNAi CONSTRUCTS AND USES THEREOF

#1195
20220049251
2022-02-17

dsRNA Directed to Coronavirus Proteins

#1196
20220049249
2022-02-17

Double-stranded oligonucleotide, composition and conjugate comprising double-stranded oligonucleotide, preparation method thereof and use thereof

#1197
20220049248
2022-02-17

MODULATORS OF IRF5 EXPRESSION

#1198
20220049240
2022-02-17

Purification methods for guanine-rich oligonucleotides

#1199
20220042021
2022-02-10

RNAi-MEDIATED INHIBITION OF HIF1A FOR TREATMENT OF OCULAR ANGIOGENESIS

#1200
20220042014
2022-02-10

APOLIPOPROTEIN C3 (APOC3) iRNA COMPOSITIONS AND METHODS OF USE THEREOF