109219 ⎘
Applications; Uses in screening processes in functional genomics, i.e. for the determination of gene function
CRISPR/CAS SCREENING PLATFORM TO IDENTIFY GENETIC MODIFIERS OF TAU SEEDING OR AGGREGATION
#2INSECT CELLS AND METHODS FOR ENGINEERING THE SAME
#3HIGH THROUGHPUT ASSAY FOR MEASURING ADENOVIRUS REPLICATION KINETICS
#4CRISPR/CAS SCREENING PLATFORM TO IDENTIFY GENETIC MODIFIERS OF TAU SEEDING OR AGGREGATION
#5A METHOD FOR REPRODUCIBLE APTAMER SELECTION USING CLOSED SEQUENCE SOLUTION SPACES
#6IN VIVO CRISPR SCREENING SYSTEM FOR DISCOVERING THERAPEUTIC TARGETS IN CD8 T CELLS
#7METHOD FOR RNAI FUNGICIDE GENERATING AND THE RNAI FUNGICIDE THEREOF
#8SYSTEMS AND METHODS FOR DETERMINING BARCODES AND SCREENING IN SITU
#9SYSTEMS AND METHODS FOR GENOME-WIDE ANNOTATION OF GENE REGULATORY ELEMENTS LINKED TO CELL FITNESS
#10CRISPR ENABLED MULTIPLEXED GENOME ENGINEERING
#11ENGINEERED NUCLEIC ACIDS TARGETING LONG NONCODING RNA INVOLVED IN PATHOGENIC INFECTION
#12CRISPR/Cas screening platform to identify genetic modifiers of tau seeding or aggregation
#13ENHANCEMENTS TO SINGLE CELL OR NUCLEUS NEXT GENERATION SEQUENCING FOR REDUCING COSTS AND IMPROVING THROUGHPUT
#14INTERNAL STANDARD FOR CRISPR GUIDE RNA
#15METHODS AND COMPOSITIONS INVOLVING CRISPR CLASS 2, TYPE VI GUIDES
#16CRISPR enabled multiplexed genome engineering
#17IN SITU CELL SCREENING METHODS AND SYSTEMS
#18IMAGING-BASED POOLED CRISPR SCREENING
#19COMPOSITIONS FOR SUPPRESSING TRIM28 AND USES THEREOF
#20CRISPR enabled multiplexed genome engineering
#21HIGH THROUGHPUT ASSAY FOR MEASURING ADENOVIRUS REPLICATION KINETICS
#22COMPOSITIONS AND METHODS FOR HIGHLY EFFICIENT GENETIC SCREENING USING BARCODED GUIDE RNA CONSTRUCTS
#23COMPOSITIONS AND METHODS FOR MODULATING EGG DEVELOPMENT IN MOSQUITOES
#24METHODS OF INHIBITING PROLIFERATIVE CELLS
#25CRISPR enabled multiplexed genome engineering
#26IDENTIFICATION AND TARGETED MODULATION OF GENE SIGNALING NETWORKS
#27Treatment of angiogenesis disorders
#28CRISPR enabled multiplexed genome engineering
#29CRISPR/Cas screening platform to identify genetic modifiers of tau seeding or aggregation
#30MODULATION OF IMMUNE RESPONSE THROUGH STIMULATOR OF INTERFERON GENES
#31METHODS FOR IDENTIFYING ACTIVATORS AND SUPPRESSORS
#32CRISPR enabled multiplexed genome engineering
#33CRISPR enabled multiplexed genome engineering
#34METHODS OF PRODUCING HUMAN CANCER CELL MODELS AND METHODS OF USE
#35Mapping a Functional Cancer Genome Atlas of Tumor Suppressors Using AAV-CRISPR Mediated Direct In Vivo Screening
#36AAV-Mediated Direct In vivo CRISPR Screen in Glioblastoma
#37CRISPR enabled multiplexed genome engineering
#38CRISPR enabled multiplexed genome engineering
#39Treatment of angiogenesis disorders
#40Efficient genetic screening method
#41COMPOSITIONS AND METHODS FOR CRISPR-BASED SCREENING
#42CRISPR enabled multiplexed genome engineering
#43METHODS AND COMPOSITIONS FOR MANIPULATING TRANSLATION OF PROTEIN ISOFORMS FROM ALTERNATIVE INITIATION START SITES
#44Production of viruses in avian eggs
#45CRISPR enabled multiplexed genome engineering
#46Human induced pluripotent stem cells for high efficiency genetic engineering
#47ANTI-TUMOR THERAPY
#48VECTORS AND SYSTEM FOR MODULATING GENE EXPRESSION
#49Identification of selected spectrum antibiotics
#50Gene modification assays
#51CRISPR enabled multiplexed genome engineering
#52High throughput assay for measuring adenovirus replication kinetics
#53Production of viruses in avian eggs
#54Tissue selective transgene expression
#55METHODS OF CONTROLLING CELL FATE AND CONSEQUENCES FOR DISEASE
#56Delivery, use and therapeutic applications of the CRISPR-cas systems and compositions for modeling mutations in leukocytes
#57CRISPR enabled multiplexed genome engineering
#58CRISPR enabled multiplexed genome engineering
#59Methods and compositions for translational profiling and molecular phenotyping
#60Small-interfering RNA expression systems for production of small-interfering RNAs and their use
#61CRISPR mediated in vivo modeling and genetic screening of tumor growth and metastasis
#62Targeting hepatitis B virus (HBV) host factors
#63HER2-regulated RNA as a diagnostic and therapeutic targets in HER2+ breast cancer
#64MOLECULAR TARGETS FOR THE PREVENTION AND/OR TREATMENT OF FIBROSIS, HYPERTROPHIC SCARS OR KELOIDS
#65Method for improving heterologous synthesis of into polyketides and use of same
#66Treatment of angiogenesis disorders
#67miRNA transcriptome methods and compositions
#68ANTI-TUMOR THERAPY
#69CRISPR enabled multiplexed genome engineering
#70Ribosomal protein L40 (RPL40) nucleic acid molecules that confer resistance to coleopteran and hemipteran pests
#71Cell lines for virus production and methods of use
#72Transmission blocking vaccines for mosquito-borne
#73MicroRNA expression in human peripheral blood microvesicles and uses thereof
#74Anti-tumor therapy
#75RECOMBINANT CELLS AND METHODS OF USING SUCH CELLS TO IDENTIFY CIRCADIAN RHYTHM MODULATORS
#76Molecular targets for the prevention and/or treatment of fibrosis, hypertrophic scars or keloids
#77Methods of identifying compounds for the treatment of fibrosis by using S1PR5
#78Methods for co-silencing expression of genes in filamentous fungal strains and uses thereof
#79Methods and compositions involving miRNA and miRNA inhibitor molecules
#80Methods and compositions involving miRNA and miRNA inhibitor molecules
#81Compositions and methods for treating peripheral arterial disease
#82Methods and compositions for translational profiling and molecular phenotyping
#83Methods for genome-wide screening and construction of genetic interaction maps
#84Fluoride-responsive riboswitches, fluoride transporters, and methods of use
#85Methods and compositions involving miRNA and miRNA inhibitor molecules
#86Metabolic gene mesenchymal signatures and uses thereof
#87Methods and compositions involving miRNA and miRNA inhibitor molecules
#88Methods and compositions involving miRNA and miRNA inhibitor molecules
#89Methods and compositions for manipulating translation of protein isoforms from alternative initiation of start sites
#90Compositions and methods for characterizing and treating muscular dystrophy
#91MicroRNA biomarkers for human breast and lung cancer
#92Method for modulating double-strand break-induced homologous recombination
#93Compositions and methods for treating cancer and modulating stress granule formation
#94Methods, agents, and compound screening assays for inducing differentiation of undifferentiated mammalian cells into osteoblasts
#95P53 MODULATOR AND CANCER TARGET
#96Isoform of bruton's tyrosine kinase (BTK) protein
#97ISOFORM OF BRUTON'S TYROSINE KINASE (BTK) PROTEIN
#98NEW ISOFORM OF BRUTON'S TYROSINE KINASE (BTK) PROTEIN
#99Influenza targets
#100Methods for identifying drug effects on a cell by determining changes in the cell's spliced message profile
#101Means and methods for the specific modulation of target genes in the CNS and the eye and methods for their identification
#102MicroRNA-10 antagonists and MicroRNA-10 targets for use in the treatment of a glioma
#103Systems and methods for individualized functional genomic profiling related to cancer cell growth
#104Methods and systems for identifying micro-RNA targets and synthesizing novel micro-RNAs and uses of the same
#105Methods for Diagnosing Stomach Cancer Using MicroRNA Signatures
#106Methods for Diagnosing Prostate Cancer Using MicroRNA Signatures
#107Methods for diagnosing lung cancer using MicroRNA signatures
#108Methods for diagnosing colon cancer using MicroRNA signatures
#109Methods for Diagnosing Breast Cancer Using MicroRNA Signatures
#110Methods for diagnosing stomach cancer using MicroRNAs
#111Methods for diagnosing prostate cancer using MicroRNAs
#112Methods for diagnosing pancreatic cancer using MicroRNAs
#113Methods for diagnosing lung cancer using microRNAs
#114Methods for diagnosing colon cancer using MicroRNAs
#115Methods for diagnosing breast cancer using MicroRNAs
#116Methods for diagnosing pancreatic cancer using miR-103-1, miR-103-2, miR-24-2 and miR-107
#117Methods for Diagnosing Breast Cancer Using miR-21, miR-125-1, miR-125b-2 and miR-145
#118Methods for Diagnosing Colon, Stomach, Prostate and Pancreas Cancer Using miR-223
#119Methods for Diagnosing Breast and Lung Cancer Using miR-210 and miR-213
#120Methods for diagnosing breast, colon, lung, pancreatic and prostate cancer using miR-21 and miR-17-5p
#121System for Synergistic Expression of Multiple Small Functional RNA Elements
#122Method for screening anticancer agent or SIP1/ZEB2 inhibitor using integrin alpha 5
#123Method and means for treatment of osteoarthritis
#124METHODS FOR EVALUATING GASTROINTESTINAL ABSORPTION OF CHEMICALS
#125POLYNUCLEOTIDE AND POLYPEPTIDE SEQUENCES INVOLVED IN CANCER
#126INHIBITION OF TRIM62 ACTIVITY REDUCES CANCER CELL PROLIFERATION
#127METHODS AND COMPOSITIONS FOR TREATING CANCER
#128Methods and compositions involving miRNA and miRNA inhibitor molecules
#129ISOLATION OF FACTORS THAT ASSOCIATE DIRECTLY OR INDIRECTLY WITH CHROMATIN
#130METHODS FOR IDENTIFYING AND COMPOUNDS USEFUL FOR THE DIAGNOSIS AND TREATMENT OF DISEASES INVOLVING INFLAMMATION
#131METHODS AND COMPOSITIONS INVOLVING MIRNA AND MIRNA INHIBITOR MOLECULES
#132RNAI BASED SELECTION SYSTEM
#133METHODS FOR IDENTIFYING AND COMPOUNDS USEFUL FOR THE DIAGNOSIS AND TREATMENT OF DISEASES INVOLVING INFLAMMATION
#134Methods of modulating mesenchymal stem cell differentiation
#135Methods for identifying and compounds useful for increasing the functional activity and cell surface expression of CF-associated mutant cystic fibrosis transmembrane conductance regulator
#136PIRNA AND USES RELATED THERETO
#137System For Synergetic Expression Of Multiple Small Functional RNA Elements
#138GENE EXPRESSION PROFILE THAT PREDICTS OVARIAN CANCER SUBJECT RESPONSE TO CHEMOTHERAPY
#139Compositions and methods for prognosis of gastric cancer
#140USE OF ENDO-LYSOSOMAL SYSTEM AND SECRETED VESICLES (EXOSOME-LIKE) IN TREATMENTS AND DIAGNOSTICS BASED ON SMALL RNA AND EXPERIMENTAL STUDY OF SMALL RNA
#141ASSAY FOR IDENTIFYING AGENTS THAT MODULATE EPIGENETIC SILENCING, AND AGENTS IDENTIFIED THEREBY
#142VIRUS-SPECIFIC miRNA SIGNATURES FOR DIAGNOSIS AND THERAPEUTIC TREATMENT OF VIRAL INFECTION
#143INFLUENZA TARGETS
#144METHODS FOR IDENTIFICATION, AND COMPOUNDS USEFUL FOR THE TREATMENT OF DEGENERATIVE & INFLAMMATORY DISEASES
#145MICRORNA-BASED DIAGNOSTIC TESTING AND THERAPIES FOR INFLAMMATORY BOWEL DISEASE AND RELATED DISEASES
#146COMPOSITIONS AND METHODS FOR TREATING CANCER AND MODULATING STRESS GRANULE FORMATION
#147TREATMENT OF CANCER
#148METHODS AND COMPOSITIONS FOR TRANSLATIONAL PROFILING AND MOLECULAR PHENOTYPING
#149NOVEL HIV TARGETS
#150MEANS AND METHODS FOR THE SPECIFIC INHIBITION OF GENES IN CELLS AND TISSUE OF THE CNS AND/OR EYE
#151Stable cell lines and methods for evaluating gastrointestinal absorption of chemicals
#152Stable cell lines and methods for evaluating gastrointestinal absorption of chemicals
#153METHODS FOR MEDIATING GENE SUPPRESSION
#154MEANS AND METHODS FOR shRNA MEDIATED CONDITIONAL KNOCKDOWN OF GENES
#155TUMOR SUPPRESSOR GENE SCREENING USING RNA INTERFERENCE LIBRARIES AND METHOD OF TREATMENT
#156Methods for detecting a target nucleotide sequence in a sample utilising a nuclease-aptamer complex
#157Pro-angiogenic genes in ovarian tumor endothelial cell isolates
#158Apoptosis inducing positive control for expression modulation experiments
#159MicroRNA expression in human peripheral blood microvesicles and uses thereof
#160TREATMENT AND PREVENTION OF HIV INFECTION
#161Screening of micro-RNA cluster inhibitor pools
#162TARGETS FOR TUMOR GROWTH INHIBITION
#163P53 modulator and cancer target
#164GENE EXPRESSION SIGNATURE FOR CLASSIFICATION OF CANCERS
#165RAS-MEDIATED EPIGENETIC SILENCING EFFECTORS AND USES THEREOF
#166METHODS AND COMPOSITIONS FOR MODULATING THE MIRNA PATHWAY
#167GENES INVOLVED IN MITOCHONDRIAL BIOGENESIS
#168METHOD AND MEANS FOR TREATMENT OF OSTEOARTHRITIS
#169Methods, agents, and compound screening assays for inducing differentiation of undifferentiated mammalian cells into osteoblasts
#170Isoform of bruton's tyrosine kinase (BTK) protein
#171Methods and compositions for regulating cell cycle progression
#172OLIGONUCLEOTIDES FOR MODULATING TARGET RNA ACTIVITY
#173MicroRNA biomarkers for human breast and lung cancer
#174Regulation of epigenetic control of gene expression
#175DOUBLE STRANDED RNA STRUCTURES AND CONSTRUCTS, AND METHODS FOR GENERATING AND USING THE SAME
#176miR-34 Regulated Genes and Pathways as Targets for Therapeutic Intervention
#177Novel HIV Targets
#178Methods and compositions for RNA interference
#179miR-10 Regulated Genes and Pathways as Targets for Therapeutic Intervention
#180Methods and compositions involving miRNA and miRNA inhibitor molecules
#181miR-20 Regulated Genes and Pathways as Targets for Therapeutic Intervention
#182Methods and compositions for silencing genes without inducing toxicity
#183Genetic selection system for identification of MicroRNA target genes
#184miR-15, miR-26, miR-31, miR-145, miR-147, miR-188, miR-215, miR-216, miR-331, mmu-miR-292-3P REGULATED GENES AND PATHWAYS AS TARGETS FOR THERAPEUTIC INTERVENTION
#185Molecular targets and compounds, and methods to identify the same, useful in the treatment of bone and joint degenerative diseases
#186miRNA PROCESSING INHIBITOR EFFICACY ASSAYS AND SUBSTANCES
#187piRNA and uses related thereto
#188Methods for identification, and compounds useful for the treatment of degenerative and inflammatory diseases
#189METHODS OF IDENTIFYING GENES INVOLVED IN MEMORY FORMATION USING SMALL INTERFERING RNA(siRNA)
#190RNA INTERFERENCE USING A UNIVERSAL TARGET
#191Human immunodeficiency virus integrase—Transportin—SR protein—protein interactions
#192Methods for Identifying Genes that Mediate a Response of a Living Cell to an Agent
#193MicroRNA-based methods and compositions for the diagnosis, prognosis and treatment of solid cancers
#194Identification of genetic alterations that modulate drug sensitivity in cancer treatments
#195Products and Methods Related to Mono-Methyl Branched-Chain Fatty Acids
#196Methods and compositions for RNA interference
#197Nanoparticles Comprising Rna Ligands
#198Methods and compositions involving miRNA and miRNA inhibitor molecules
#199Methods and compositions involving miRNA and miRNA inhibitor molecules
#200Stable cell lines and methods for evaluating gastrointestinal absorption of chemicals
#201MODULATION OF GENE EXPRESSION USING DNA-RNA HYBRIDS
#202Agent for Inducing senescence and apoptosis of cancer cell
#203Methods and compositions involving miRNA and miRNA inhibitor molecules
#204MicroRNA biomarkers for human breast and lung cancer
#205Compositions and methods for altering RNAi
#206Method for preparing short hairpin RNA from CDNA
#207Modified triple-helix forming oligonucleotides for targeted mutagenesis
#208Methods, agents, and compound screening assays for inducing differentiation of undifferentiatied mammalian cells into osteoblasts
#209Methods and compositions for RNA interference
#210Methods of modulating angiogenesis and screening compounds for activity in modulating angiogenesis
#211Use of eukaryotic genes affecting spindle formation or microtubule function during cell division for diagnosis and treatment of proliferative diseases
#212Method of identifying agents that inhibit the growth of cancer cells
#213Methods of treatment and diagnosis using modulators of virus-induced cellular gene sequences
#214Methods and compositions for silencing genes without inducing toxicity
#215GLUCOSE TRANSPORT-RELATED GENES, POLYPEPTIDES, AND METHODS OF USE THEREOF
#216Method and systems for identifying micro-RNA targets and synthesizing novel micro-RNAs and uses of the same
#217Methods and compositions for RNA interference
#218Method and means for treatment of osteoarthritis
#219Targets for tumor growth inhibition
#220Methods of treatment and diagnosis of kaposi's sarcoma (ks) and ks related diseases
#221Methods and compositions for evaluating cell function in sensory neurons
#222Target validation assay
#223Apparatus and system having dry control gene silencing compositions
#224Eukaryotic genes involved in adult lifespan regulation
#225Methods and compositions for RNA interference
#226Method of determining a cellular response to a biological agent
#227Human immunodeficiency virus integrase-LEDGF p75 isoform protein-protein interactions
#228Methods for identification, and compounds useful for the treatment of degenerative & inflammatory diseases
#229Means and methods for the specific modulation of target genes in the CNS and the eye and methods for their identification
#230Use of interfering RNA in the production of transgenic animals
#231Reagents and methods for identification of RNAi pathway genes and chemical modulators of RNAi
#232Compositions and methods that modulate RNA interference
#233Double stranded rna structures and constructs, and methods for generating and using the same
#234Means and methods for the specific inhibition of genes in cells and tissue of the cns and/or eye
#235siRNA knockout assay method and constructs
#236Interspersed repetitive element RNAs as substrates, inhibitors and delivery vehicles for RNAi
#237Synthetic lethal screen using RNA interference
#238Modulation of gene expression using DNA-RNA hybrids
#239Modulation of gene expression using DNA-DNA hybrids
#240RNA interference mediated target discovery and target validation using short interfering nucleic acid (siNA)
#241High-throughput transcriptome and functional validation analysis
#242Methods and compositions for selective RNAi mediated inhibition of gene expression in mammal cells
#243Methods and compositions for modulating apoptosis