ClassID:

109236

C12N2330/51 - CPC Classification

Classification description:

Production; Biochemical production, i.e. in a transformed host cell Specially adapted vectors

Recent Application in this class:
#1
20260125432
2026-05-07

MALTOSE DEPENDENT DEGRONS, MALTOSE-RESPONSIVE PROMOTERS, STABILIZATION CONSTRUCTS, AND THEIR USE IN PRODUCTION OF NON-CATABOLIC COMPOUNDS

#2
20260049320
2026-02-19

RECOMBINANT VIRUS PRODUCTS AND METHODS FOR INHIBITING EXPRESSION OF DYSTROPHIA MYOTONICA PROTEIN KINASE AND/OR INTERFERING WITH A TRINUCLEOTIDE REPEAT EXPANSION IN THE 3' UNTRANSLATED REGION OF THE DMPK GENE

#3
20260027235
2026-01-29

ADENO-ASSOCIATED VIRUS VECTOR DELIVERY OF MICRO-DYSTROPHIN TO TREAT MUSCULAR DYSTROPHY

#4
20250361532
2025-11-27

BIDIRECTIONAL MULTI-ENZYMATIC SCAFFOLDS FOR BIOSYNTHESIZING CANNABINOIDS

#5
20250249052
2025-08-07

COMPOSITIONS AND METHODS FOR MUSCLE DISORDERS

#6
20250235556
2025-07-24

GENE THERAPY FOR AUTOSOMAL DOMINANT DISEASES

#7
20250197884
2025-06-19

INSECT CELLS AND METHODS FOR ENGINEERING THE SAME

#8
20250161490
2025-05-22

ADENO-ASSOCIATED VIRUS VECTOR DELIVERY OF MICRO-DYSTROPHIN TO TREAT MUSCULAR DYSTROPHY

#9
20250146000
2025-05-08

COMPOSITIONS AND METHODS OF TREATING AMYOTROPHIC LATERAL SCLEROSIS (ALS)

#10
20250121051
2025-04-17

HIV PRE-IMMUNIZATION AND IMMUNOTHERAPY

#11
20250121050
2025-04-17

METHODS OF PRODUCING CELLS RESISTANT TO HIV INFECTION

#12
20250019697
2025-01-16

MODIFIED U6 PROMOTER SYSTEM FOR TISSUE SPECIFIC EXPRESSION

#13
20240415868
2024-12-19

COMPOSITIONS AND METHODS FOR TREATING HUNTINGTON'S DISEASE

#14
20240409940
2024-12-12

MODIFIED AAV CONSTRUCTS AND USES THEREOF

#15
20240336934
2024-10-10

CRISPR/CAS9-BASED COMPOSITIONS AND METHODS FOR TREATING RETINAL DEGENERATIONS

#16
20240318201
2024-09-26

RECOMBINANT VIRUS PRODUCTS AND METHODS FOR INHIBITION OF EXPRESSION OF DUX4

#17
20240263172
2024-08-08

CRISPR TRANSIENT EXPRESSION CONSTRUCT (CTEC)

#18
20240238406
2024-07-18

HIV PRE-IMMUNIZATION AND IMMUNOTHERAPY

#19
20240175046
2024-05-30

VECTORS

#20
20240165145
2024-05-23

COMPOSITIONS AND METHODS FOR TREATING CANCER AND BIOMARKERS TO DETECT CANCER STEM CELL REPROGRAMMING AND PROGRESSION

#21
20240141386
2024-05-02

COMPOSITIONS AND METHODS FOR TREATING CEP290 ASSOCIATED DISEASE

#22
20240108714
2024-04-04

PRE-IMMUNIZATION AND IMMUNOTHERAPY

#23
20240091339
2024-03-21

PRE-IMMUNIZATION AND IMMUNOTHERAPY

#24
20240084303
2024-03-14

AAV TREATMENT OF HUNTINGTON’S DISEASE

#25
20240076668
2024-03-07

RAAV-BASED COMPOSITIONS AND METHODS FOR TREATING AMYOTROPHIC LATERAL SCLEROSIS

#26
20240043849
2024-02-08

ENGINEERED VIRAL VECTOR REDUCES INDUCTION OF INFLAMMATORY AND IMMUNE RESPONSES

#27
20240043845
2024-02-08

COMPOSITIONS AND METHODS FOR TREATING BETA-HEMOGLOBINOPATHIES

#28
20230416738
2023-12-28

VIRAL VECTORS AND NUCLEIC ACIDS FOR USE IN THE TREATMENT OF ILD, PF-ILD AND IPF

#29
20230399642
2023-12-14

COMPOSITIONS AND METHODS OF TREATING HUNTINGTON'S DISEASE

#30
20230397612
2023-12-14

miRNA, and Derivative Thereof and Use Thereof

#31
20230332180
2023-10-19

USE OF NOVEL MIRNA-BINDING SITE CASSETTES FOR ANTIGEN-PRESENTING CELL DETARGETING OF TRANSGENE EXPRESSION BY RAAV GENE THERAPY

#32
20230332156
2023-10-19

Compositions and methods of treating amyotrophic lateral sclerosis (ALS)

#33
20230323391
2023-10-12

TRANSGENE EXPRESSION SYSTEM

#34
20230295659
2023-09-21

TARGETING PEPTIDES FOR DIRECTING ADENO-ASSOCIATED VIRUSES (AAVs)

#35
20230277579
2023-09-07

METHODS AND COMPOSITIONS FOR THE ACTIVATION OF GAMMA-DELTA T-CELLS

#36
20230265465
2023-08-24

BIDIRECTIONAL MULTI-ENZYMATIC SCAFFOLDS FOR BIOSYNTHESIZING CANNABINOIDS

#37
20230257756
2023-08-17

REAL-TIME CELLULAR THERMAL SHIFT ASSAY (RT-CETSA) FOR RESEARCH AND DRUG DISCOVERY

#38
20230241200
2023-08-03

HIV PRE-IMMUNIZATION AND IMMUNOTHERAPY

#39
20230235354
2023-07-27

ENHANCEMENT OF THE PRODUCTION OF ADENOIDVIRUS-BASED GENETRANSFER VECTORS

#40
20230235325
2023-07-27

Compositions and Methods for Treating Huntington's Disease and Related Disorders

#41
20230173101
2023-06-08

ADENO-ASSOCIATED VIRUS VECTOR DELIVERY OF MICRO-DYSTROPHIN TO TREAT MUSCULAR DYSTROPHY

#42
20230144548
2023-05-11

RECOMBINANT AAV VECTORS WITH ALTERED IMMUNOGENCITY AND METHODS OF MAKING THE SAME

#43
20230119344
2023-04-20

RNAI INDUCED HUNTINGTIN GENE SUPPRESSION

#44
20230115116
2023-04-13

ONCOLYTIC VIRAL VECTORS AND USES THEREOF

#45
20230093951
2023-03-30

REAGENTS FOR TREATMENT OF HEPATITIS B VIRUS (HBV) INFECTION AND USE THEREOF

#46
20230077409
2023-03-16

Modified U6 promoter system for tissue specific expression

#47
20230070527
2023-03-09

POTATO TRANSFORMATION VECTORS

#48
20230070049
2023-03-09

MICRORNA-7 COMPOSITIONS FOR PROMOTING FUNCTIONAL RECOVERY FOLLOWING SPINAL CORD INJURY AND METHODS OF USE THEREOF

#49
20230056466
2023-02-23

NOVEL PRECURSOR MIRNA AND APPLICATION THEREOF IN TUMOR TREATMENT

#50
20230025574
2023-01-26

Recombinant Adeno-Associated Virus Delivery of Exon 2-Targeted U7SNRNA Polynucleotide Constructs

#51
20230015505
2023-01-19

MODULAR, CELL-FREE PROTEIN EXPRESSION VECTORS TO ACCELERATE BIOLOGICAL DESIGN IN CELLS

#52
20230001015
2023-01-05

Adeno-Associated Virus Vector Delivery of Microrna-29 to Treat Muscular Dystrophy

#53
20220411792
2022-12-29

NUCLEIC ACID COMPOSITIONS

#54
20220380778
2022-12-01

XYLANASE MUTANT HAVING IMPROVED SPECIFIC ACTIVITY

#55
20220333103
2022-10-20

GENE VECTOR

#56
20220290186
2022-09-15

GENE EDITING USING A MODIFIED CLOSED-ENDED DNA (CEDNA)

#57
20220288141
2022-09-15

GENERATION OF NEURONS BY REPROGRAMMING OF OLIGODENDROCYTES AND OLIGODENDROCYTE PRECURSOR CELLS

#58
20220288101
2022-09-15

COMBINED TRANSGENE AND INTRON-DERIVED MIRNA THERAPY FOR TREATMENT OF SCA1

#59
20220282262
2022-09-08

SYNTHESIS OF THE FUCOSYLATED OLIGOSACCHARIDE LNFP-V

#60
20220267783
2022-08-25

FILAMENTOUS FUNGAL EXPRESSION SYSTEM

#61
20220267768
2022-08-25

Recombinant virus products and methods for inducing DUX4 exon skipping

#62
20220259594
2022-08-18

VECTORS AND COMPOSITIONS FOR TREATING HEMOGLOBINOPATHIES

#63
20220235372
2022-07-28

Use of novel miRNA-binding site cassettes for antigen-presenting cell detargeting of transgene expression by rAAV gene therapy vectors

#64
20220235330
2022-07-28

METHODS FOR CREATING INTEGRATION-FREE, VIRUS-FREE, EXOGENOUS ONCOGENE-FREE IPS CELLS AND COMPOSITIONS FOR USE IN SUCH METHODS

#65
20220213503
2022-07-07

VIRAL VECTORS AND NUCLEIC ACIDS FOR USE IN THE TREATMENT OF PF-ILD AND IPF

#66
20220213455
2022-07-07

Thermostable CAS9 nucleases

#67
20220195460
2022-06-23

RETROVIRAL VECTOR HAVING IMMUNE-STIMULATING ACTIVITY

#68
20220186257
2022-06-16

AAV-CAS13D VECTORS AND USES THEREOF

#69
20220186251
2022-06-16

VIRAL VECTORS FOR THE TREATMENT OF DIABETES

#70
20220168450
2022-06-02

TREATMENT OF AMYOTROPHIC LATERAL SCLEROSIS AND DISORDERS ASSOCIATED WITH THE SPINAL CORD

#71
20220127607
2022-04-28

METHODS AND MATERIALS FOR ACTIVATING AN INTERNAL RIBOSOME ENTRY SITE IN EXON 5 OF THE DMD GENE

#72
20220112504
2022-04-14

METHODS AND COMPOSITIONS FOR ALLELE SPECIFIC GENE EDITING

#73
20220106609
2022-04-07

PARAVOVIRAL VECTORS AND METHODS OF MAKING AND USE THEREOF

#74
20220064641
2022-03-03

RECOMBINANT VIRUS PRODUCTS AND METHODS FOR INHIBITION OF EXPRESSION OF MYOTILIN

#75
20220056460
2022-02-24

CRISPR GUIDE-RNA EXPRESSION STRATEGIES FOR MULTIPLEX GENOME ENGINEERING

#76
20220056446
2022-02-24

Reagents for treatment of oculopharyngeal muscular dystrophy (OPMD) and use thereof

#77
20220054657
2022-02-24

Gene therapy for retinitis pigmentosa

#78
20220033823
2022-02-03

RECOMBINANT VIRUS PRODUCTS AND METHODS FOR INHIBITING EXPRESSION OF DYSTROPHIA MYOTONICA PROTEIN KINASE AND/OR INTERFERING WITH A TRINUCLEOTIDE REPEAT EXPANSION IN THE 3' UNTRANSLATED REGION OF THE DMPK GENE

#79
20220010312
2022-01-13

AAV treatment of Huntington's disease

#80
20210401868
2021-12-30

Safe lentiviral vectors for targeted delivery of multiple therapeutic molecules

#81
20210380981
2021-12-09

Anti-angiogenic miRNA therapeutics for inhibiting corneal neovascularization

#82
20210371859
2021-12-02

RNA MEDIATED GENE REGULATING METHODS

#83
20210363530
2021-11-25

Splice inhibiting oligonucleotides

#84
20210348170
2021-11-11

Compositions and methods for treating beta-hemoglobinopathies

#85
20210340539
2021-11-04

Modified AAV constructs and uses thereof

#86
20210340532
2021-11-04

Thermostable Cas9 nucleases

#87
20210330783
2021-10-28

HIV pre-immunization and immunotherapy

#88
20210324387
2021-10-21

AAV VECTORS FOR TREATMENT OF DOMINANT RETINITIS PIGMENTOSA

#89
20210317475
2021-10-14

RECOMBINANT AAV VECTORS USEFUL FOR REDUCING IMMUNITY AGAINST TRANSGENE PRODUCTS

#90
20210316013
2021-10-14

HAEMATOPOIETIC STEM CELL-GENE THERAPY FOR WISKOTT-ALDRICH SYNDROME

#91
20210301292
2021-09-30

Compositions of Asymmetric Interfering RNA and Uses Thereof

#92
20210284979
2021-09-16

METHODS AND COMPOSITIONS FOR GENETICALLY MANIPULATING GENES AND CELLS

#93
20210269804
2021-09-02

MULTIPLEXED SHRNAS AND USES THEREOF

#94
20210261981
2021-08-26

GENE THERAPIES FOR NEURODEGENERATIVE DISEASES

#95
20210261954
2021-08-26

Method for generating a gene editing vector with fixed guide RNA pairs

#96
20210254093
2021-08-19

DOWN-REGULATING GENE EXPRESSION IN INSECT PLANTS

#97
20210254068
2021-08-19

GENOME ENGINEERING PRIMARY MONOCYTES

#98
20210246450
2021-08-12

RAAV-based compositions and methods for treating amyotrophic lateral sclerosis

#99
20210230234
2021-07-29

MALTOSE DEPENDENT DEGRONS, MALTOSE-RESPONSIVE PROMOTERS, STABILIZATION CONSTRUCTS, AND THEIR USE IN PRODUCTION OF NON-CATABOLIC COMPOUNDS

#100
20210214749
2021-07-15

DIRECTED EVOLUTION

#101
20210205476
2021-07-08

Isolation of novel AAV's and uses thereof

#102
20210198739
2021-07-01

METHODS FOR DETERMINING THE PRESENCE OR RISK OF DEVELOPING FACIOSCAPULOHUMERAL DYSTROPHY (FSHD)

#103
20210155941
2021-05-27

COMPOSITIONS AND METHODS FOR MAKING ENGINEERED T CELLS

#104
20210154326
2021-05-27

CRISPR-Based Synthetic Gene Circuits as Next Generation Gene Therapy of Inner Ear

#105
20210139915
2021-05-13

Compositions and methods of treating amyotrophic lateral sclerosis (ALS)

#106
20210139905
2021-05-13

Oligonucleotide therapy for Leber congenital amaurosis

#107
20210121561
2021-04-29

Methods of producing cells resistant to HIV infection

#108
20210108197
2021-04-15

SHRNA EXPRESSION CASSETTE, POLYNUCLEOTIDE SEQUENCE CARRYING SAME, AND APPLICATION THEREOF

#109
20210095292
2021-04-01

Use of MIR101 or MIR128 in the treatment of seizure disorders

#110
20210071174
2021-03-11

CRISPR TRANSIENT EXPRESSION CONSTRUCT (CTEC)

#111
20210032627
2021-02-04

GENE THERAPEUTIC FOR THE TREATMENT OF HIV AND USES THEREOF

#112
20210008093
2021-01-14

Methods and compositions for the activation of gamma-delta T-cells

#113
20200399326
2020-12-24

MALTOSE DEPENDENT DEGRONS, MALTOSE-RESPONSIVE PROMOTERS, STABILIZATION CONSTRUCTS, AND THEIR USE IN PRODUCTION OF NON-CATABOLIC COMPOUNDS

#114
20200392500
2020-12-17

AAV-based treatment of cholesterol-related disorders

#115
20200385738
2020-12-10

H-1 PV EXPRESSING RNAI EFFECTORS TARGETING CDK9

#116
20200377887
2020-12-03

COMPOSITIONS AND METHODS OF TREATING HUNTINGTON'S DISEASE

#117
20200370042
2020-11-26

COMPOSITIONS AND METHODS FOR CORRECTING DYSTROPHIN MUTATIONS IN HUMAN CARDIOMYOCYTES

#118
20200352977
2020-11-12

ANTISENSE OLIGONUCLEOTIDES FOR THE TREATMENT OF LEBER CONGENITAL AMAUROSIS

#119
20200340011
2020-10-29

RECOMBINANT INSECT VECTORS AND METHODS OF USE

#120
20200339992
2020-10-29

RNAi induced huntingtin gene suppression

#121
20200325477
2020-10-15

Compositions and Methods for Inducing an Enhanced Immune Response Using Poxvirus Vectors

#122
20200268907
2020-08-27

Compositions and methods for the expression of CRISPR guide RNAs using the H1 promoter

#123
20200263165
2020-08-20

METHODS AND COMPOSITIONS FOR POLYMERASE II (POL-II) BASED GUIDE RNA EXPRESSION

#124
20200260698
2020-08-20

EXON DELETION CORRECTION OF DUCHENNE MUSCULAR DYSTROPHY MUTATIONS IN THE DYSTROPHIN ACTIN BINDING DOMAIN 1 USING CRISPR GENOME EDITING

#125
20200216850
2020-07-09

Splice inhibiting oligonucleotides

#126
20200165641
2020-05-28

Bidirectional multi-enzymatic scaffolds for biosynthesizing cannabinoids

#127
20200165607
2020-05-28

COMPOSITION AND METHOD OF USING MIR-302 PRECURSORS AS ANTI-CANCER DRUGS FOR TREATING HUMAN LUNG CANCER

#128
20200157547
2020-05-21

Compositions and methods of treating amyotrophic lateral sclerosis (ALS)

#129
20200155590
2020-05-21

Safe lentiviral vectors for targeted delivery of multiple therapeutic molecules

#130
20200147156
2020-05-14

Oncolytic viral vectors and uses thereof

#131
20200140884
2020-05-07

DOWN-REGULATING GENE EXPRESSION IN INSECT PLANTS

#132
20200123574
2020-04-23

Compositions and methods of treating amyotrophic lateral sclerosis (ALS)

#133
20200109417
2020-04-09

HIV pre-immunization and immunotherapy

#134
20200109399
2020-04-09

Vectors and compositions for treating hemoglobinopathies

#135
20200087664
2020-03-19

AAV treatment of Huntington's disease

#136
20200080108
2020-03-12

CRISPR/CAS9-BASED COMPOSITIONS AND METHODS FOR TREATING RETINAL DEGENERATIONS

#137
20200071696
2020-03-05

Compositions of asymmetric interfering RNA and uses thereof

#138
20200063134
2020-02-27

Oligonucleotide therapy for Leber Congenital Amaurosis

#139
20200063128
2020-02-27

Compositions of asymmetric interfering RNA and uses thereof

#140
20200063124
2020-02-27

Methods for RNA promoter identification

#141
20200046851
2020-02-13

Gene therapy for retinitis pigmentosa

#142
20200032256
2020-01-30

RAAV-based compositions and methods for treating amyotrophic lateral sclerosis

#143
20200032221
2020-01-30

Cell culture methods involving HDAC inhibitors or rep proteins

#144
20190388456
2019-12-26

Methods and compositions for the activation of gamma-delta T-cells

#145
20190367911
2019-12-05

Gene vector

#146
20190365928
2019-12-05

Compositions and methods for the expression of CRISPR guide RNAS using the H1 promoter

#147
20190360002
2019-11-28

Thermostable Cas9 nucleases

#148
20190338314
2019-11-07

Exosome delivery system

#149
20190338311
2019-11-07

OPTIMIZED STRATEGY FOR EXON SKIPPING MODIFICATIONS USING CRISPR/CAS9 WITH TRIPLE GUIDE SEQUENCES

#150
20190338285
2019-11-07

Reagents for treatment of hepatitis B virus (HBV) infection and use thereof

#151
20190330672
2019-10-31

Highly efficient and tunable system for the incorporation of unnatural amino acids into proteins in

#152
20190330647
2019-10-31

Methods and compositions for multiplex RNA guided genome editing and other RNA technologies

#153
20190330629
2019-10-31

Reagents for treatment of oculopharyngeal muscular dystrophy (OPMD) and use thereof

#154
20190322993
2019-10-24

Thermostable CAS9 nucleases

#155
20190316126
2019-10-17

RAAV-based compositions and methods for treating amyotrophic lateral sclerosis

#156
20190316101
2019-10-17

METHODS AND COMPOSITIONS FOR GENETICALLY MANIPULATING GENES AND CELLS

#157
20190316095
2019-10-17

Methods for creating integration-free, virus-free, exogenous oncogene-free IPS cells and compositions for use in such methods

#158
20190314521
2019-10-17

Compositions and methods comprising improvements of CRISPR guide RNAS using the H1 promoter

#159
20190314421
2019-10-17

NUCLEIC ACID CONSTRUCTS INCLUDING A TXNIP PROMOTER FOR THE TREATMENT OF DISEASE

#160
20190314313
2019-10-17

HOMEOSTATIC REGULATION OF L-DOPA BIOSYNTHESIS

#161
20190307809
2019-10-10

Methods and compositions for in vivo induction of pancreatic beta cell formation

#162
20190300903
2019-10-03

Recombinant virus products and methods for inhibition of expression of DUX4

#163
20190300877
2019-10-03

METHODS AND COMPOSITIONS FOR T-RNA BASED GUIDE RNA EXPRESSION

#164
20190292539
2019-09-26

Method for modifying genes

#165
20190290780
2019-09-26

Compositions and methods for mitochondrial genome editing

#166
20190284559
2019-09-19

E. COLI MEDIATED siRNA SILENCING OF AVIAN INFLUENZA IN CHICKENS

#167
20190282709
2019-09-19

Isolation of novel AAV's and uses thereof

#168
20190282639
2019-09-19

Viral vectors for treating Parkinson's disease

#169
20190276830
2019-09-12

Novel Paratransgenic System for the Biocontrol of Disease-Transmitting Mosquitos

#170
20190276826
2019-09-12

RAAV-based compositions and methods for treating amyotrophic lateral sclerosis

#171
20190276822
2019-09-12

Recombinant adeno-associated virus delivery of exon 2-targeted U7SNRNA polynucleotide constructs

#172
20190264206
2019-08-29

MicroRNA-200 based approaches for modulating bone formation inhibition and bone regeneration

#173
20190256858
2019-08-22

AAV delivery of shRNA for treatment of pancreatic cancer

#174
20190249174
2019-08-15

Recombinant virus products and methods for inhibition of expression of myotilin

#175
20190225969
2019-07-25

CTLA-4-targeting trans-splicing ribozyme for delivery of chimeric antigen receptor, and use thereof

#176
20190218573
2019-07-18

HIV pre-immunization and immunotherapy

#177
20190218559
2019-07-18

siRNA knocking down human PD-1 and recombinant expression CAR-T vector and their construction methods and applications

#178
20190201523
2019-07-04

HIV pre-immunization and immunotherapy

#179
20190200589
2019-07-04

Anti-aging transgenic Caenorhabditis elegans

#180
20190194692
2019-06-27

CRISPR-CAS system for a filamentous fungal host cell

#181
20190185853
2019-06-20

AAV-based treatment of cholesterol-related disorders

#182
20190185819
2019-06-20

Human induced pluripotent stem cells for high efficiency genetic engineering

#183
20190177731
2019-06-13

Engineered viral vector reduces induction of inflammatory and immune responses

#184
20190169652
2019-06-06

Compositions and methods for treating CEP290 associated disease

#185
20190169619
2019-06-06

Use of MIR101 or MIR128 in the treatment of seizure disorders

#186
20190161730
2019-05-30

COMPOSITIONS AND METHODS RELATED TO THERAPEUTIC CELL SYSTEMS EXPRESSING EXOGENOUS RNA

#187
20190160091
2019-05-30

Compositions and methods for treating Huntington's disease

#188
20190153448
2019-05-23

Inhibitory RNA-based therapeutics targeting ANLN for cancer treatment

#189
20190144860
2019-05-16

RNAi induced huntingtin gene suppression

#190
20190136235
2019-05-09

Modified U6 promoter system for tissue specific expression

#191
20190117795
2019-04-25

Adeno-associated virus vector delivery of microrna-29 to treat muscular dystrophy

#192
20190112607
2019-04-18

Cancer therapy

#193
20190100759
2019-04-04

Compositions and methods for treating beta-hemoglobinopathies

#194
20190093111
2019-03-28

AAV vectors for treatment of dominant retinitis pigmentosa

#195
20190093110
2019-03-28

System for the biocontrol of disease-transmitting mosquitoes and their eggs using horizontally transferable symbiotic bacteria to deliver pathogen specific interfering RNA polynucleotides

#196
20190085335
2019-03-21

In-vitro induction of adult stem cell expansion and derivation

#197
20190085325
2019-03-21

Conditional CRISPR sgRNA expression

#198
20190083523
2019-03-21

Methods and compositions for the activation of gamma-delta T-cells

#199
20190071671
2019-03-07

Therapeutic for treatment of diseases including the central nervous system

#200
20190060489
2019-02-28

Adeno-associated virus vector delivery of microRNA-29 and micro-dystrophin to treat muscular dystrophy

#201
20190055581
2019-02-21

Adeno-associated virus vector delivery of micro-dystrophin to treat muscular dystrophy

#202
20190055552
2019-02-21

Compositions and methods for treating Huntington's disease and related disorders

#203
20190048343
2019-02-14

Anti-angiogenic miRNA therapeutics for inhibiting corneal neovascularization

#204
20190046633
2019-02-14

Method of producing cells resistant to HIV infection

#205
20190032090
2019-01-31

Compositions and Methods to Treat Latent Viral Infections

#206
20190024083
2019-01-24

Recombinant virus products and methods for inducing DUX4 exon skipping

#207
20190024081
2019-01-24

Nucleic acid molecule, expression cassette, expression vector, eukaryotic host cell, induction method of RNA interference in eukaryotic host and use of the nucleic acid molecule in therapy of diseases induced by expansion of trinucleotide CAG repeats

#208
20190010493
2019-01-10

Treatment of heart disease by inhibtion of the action of muscle A-kinase anchoring protein (mAKAP)

#209
20180369420
2018-12-27

Compositions and methods for the expression of CRISPR guide RNAs using the H1 promoter

#210
20180339004
2018-11-29

Oncolytic viral vectors and uses thereof

#211
20180334675
2018-11-22

Culicinae Mosquito TRA-2 RNA Interference Technique to Genetically Produce Maleness Population

#212
20180327757
2018-11-15

Enhanced protein expression and methods thereof

#213
20180320198
2018-11-08

Methods and compositions for integration defective lentiviral vectors

#214
20180320180
2018-11-08

AGE-RELATED MACULAR DEGENERATION TREATMENT

#215
20180298380
2018-10-18

Modified AAV constructs and uses thereof

#216
20180291402
2018-10-11

Linalool composition and method of producing therefor

#217
20180282732
2018-10-04

Compositions and methods of treating amyotrophic lateral sclerosis (ALS)

#218
20180273951
2018-09-27

Methods for modulating KLHL1 levels, methods for modulating current activity in T-type calcium channels, molecules therefor, and methods for identifying molecules therefor

#219
20180273939
2018-09-27

RNA and method for specifically activating human RSPO2 gene with CRISPR-Cas9 and application thereof

#220
20180265893
2018-09-20

Viral vectors for the treatment of diabetes

#221
20180255751
2018-09-13

Delivery, use and therapeutic applications of the CRISPR-cas systems and compositions for modeling mutations in leukocytes

#222
20180223277
2018-08-09

Precursor miRNA and applications in tumor therapy thereof

#223
20180222917
2018-08-09

Compositions and methods for treating leukemia

#224
20180216110
2018-08-02

Paratransgenic system for the biocontrol of disease-transmitting mosquitos

#225
20180201927
2018-07-19

NOVEL PRECURSOR MIRNA AND APPLICATION THEREOF IN TUMOR TREATMENT

#226
20180201689
2018-07-19

Antibody Fusion Protein and Preparation Method and Use Thereof

#227
20180200388
2018-07-19

Compositions and methods for the expression of CRISPR guide RNAs using the H1 promoter

#228
20180187188
2018-07-05

Cancer specific-splicing ribozyme and use thereof

#229
20180186841
2018-07-05

Maltose dependent degrons, maltose-responsive promoters, stabilization constructs, and their use in production of non-catabolic compounds

#230
20180171354
2018-06-21

Vectors

#231
20180171341
2018-06-21

Maltose dependent degrons, maltose-responsive promoters, stabilization constructs, and their use in production of non-catabolic compounds

#232
20180171309
2018-06-21

Immortalised chicken embryo fibroblasts

#233
20180169269
2018-06-21

Methods of delivery of transgenes for treating brain diseases

#234
20180163206
2018-06-14

In vivo production of small interfering RNAs that mediate gene silencing

#235
20180161455
2018-06-14

NON-INTEGRATING VIRAL DELIVERY SYSTEM AND METHODS OF USE THEROF

#236
20180155715
2018-06-07

RNA-guided transcriptional regulation and methods of using the same for the treatment of back pain

#237
20180155713
2018-06-07

Methods for RNA promoter identification

#238
20180148737
2018-05-31

Down-regulating gene expression in insect plants

#239
20180148711
2018-05-31

GENOME EDITING VECTORS

#240
20180117076
2018-05-03

MiRNA compositions for the treatment of mature B-cell neoplasms

#241
20180112225
2018-04-26

Cyanobacterial strains capable of utilizing phosphite

#242
20180094264
2018-04-05

AAV treatment of Huntington's disease

#243
20180044670
2018-02-15

Gene vector

#244
20180044662
2018-02-15

Use and production of CHD8+/− transgenic animals with behavioral phenotypes characteristic of autism spectrum disorder

#245
20180030546
2018-02-01

Identification of a 5-Gene Expression Signature Predicting Clinical Outcome of Patients with Brain Tumors

#246
20180030449
2018-02-01

Replication capable rAAV vectors encoding inhibitory siRNA and methods of their use

#247
20180030439
2018-02-01

Oligonucleotide therapy for leber congenital amaurosis

#248
20180010130
2018-01-11

Double-stranded ribonucleic acid as control against insects

#249
20170369877
2017-12-28

Reduction of off-target RNA interference toxicity

#250
20170355989
2017-12-14

RNAI induced huntingtin gene suppression

#251
20170354130
2017-12-14

Method of conveniently producing genetically modified non-human mammal with high efficiency

#252
20170342418
2017-11-30

USE OF MICRORNA PRECURSORS AS DRUGS FOR INDUCING CD34-POSITIVE ADULT STEM CELL EXPANSION

#253
20170327827
2017-11-16

ADIPOCYTE-SPECIFIC CONSTRUCTS AND METHODS FOR INHIBITING PLATELET-TYPE 12 LIPOXYGENASE EXPRESSION

#254
20170321192
2017-11-09

Recombinant RNA Viruses and Uses Thereof

#255
20170314040
2017-11-02

Fusarium chitin synthase gene chs3b and the use thereof

#256
20170314020
2017-11-02

MicroRNA-200 based approaches for modulating bone formation inhibition and bone regeneration

#257
20170312318
2017-11-02

Methods and compositions for in vivo induction of pancreatic beta cell formation

#258
20170306399
2017-10-26

Methods for characterizing alternatively or aberrantly spliced mRNA isoforms

#259
20170306335
2017-10-26

RNA-targeting system

#260
20170306326
2017-10-26

Microrna inhibitor system and methods of use thereof

#261
20170304465
2017-10-26

Adeno-associated viral vectors for treating myocilin (MYOC) glaucoma

#262
20170298350
2017-10-19

Methods and compositions for use of non-coding RNA in cell culturing and selection

#263
20170292959
2017-10-12

PLASMIDS COMPRISING INTERNAL RIBOSOMAL ENTRY SITES AND USES THEREOF

#264
20170240899
2017-08-24

Multiplexed shRNAs and uses thereof

#265
20170239370
2017-08-24

Magnetic control of gene delivery in vivo

#266
20170232097
2017-08-17

Live attenuated viral vaccine created by self-attenuation with species-specific artificial MicroRNA

#267
20170218366
2017-08-03

Methods and materials for activating an internal ribosome entry site in exon 5 of the DMD gene

#268
20170198295
2017-07-13

Nurr1 as a genetic target for treating levodopa-induced dyskinesias in Parkinson's disease

#269
20170183670
2017-06-29

Isolated oleaginous yeast

#270
20170175137
2017-06-22

Retroviral vector having immune-stimulating activity

#271
20170175118
2017-06-22

Composition and method of using miR-302 precursors as anti-cancer drugs for treating human lung cancer

#272
20170173183
2017-06-22

Gene therapy for retinitis pigmentosa

#273
20170166927
2017-06-15

Isolation of novel AAV's and uses thereof

#274
20170166926
2017-06-15

Targeting peptides for directing adeno-associated viruses (AAVs)

#275
20170166925
2017-06-15

Recombinant AAV vectors useful for reducing immunity against transgene products

#276
20170165377
2017-06-15

Isolation of novel AAV's and uses thereof

#277
20170152517
2017-06-01

Treatment of amyotrophic lateral sclerosis

#278
20170114340
2017-04-27

RAAV-based compositions and methods for treating amyotrophic lateral sclerosis

#279
20170051280
2017-02-23

Methods and compositions for inhibiting retinopathy of prematurity

#280
20170044549
2017-02-16

SiRNA in tandem expression and uses thereof in treating chronic lymphocytic leukemia

#281
20170029849
2017-02-02

Recombinant virus products and methods for inhibition of expression of DUX4

#282
20170029843
2017-02-02

Method and compositions for controlling pest insects on plants by silencing genes of the chitin synthase and of the vitellogenin family, as well as alternatively by expressing the gene of a cry toxin

#283
20170022499
2017-01-26

METHODS AND COMPOSITIONS FOR THE PRODUCTION OF GUIDE RNA

#284
20160376586
2016-12-29

Nucleic acid molecule, expression cassette, expression vector, eukaryotic host cell, induction method of RNA interferencde in eukaryotic host and use of the nucleic acid molecule in therapy of diseases induced by expansion of trinucleotide CAG repeats

#285
20160362685
2016-12-15

In vivo production of small interfering RNAs that mediate gene silencing

#286
20160333361
2016-11-17

DNA vector production system

#287
20160310548
2016-10-27

Recombinant virus products and methods for inhibition of expression of myotilin

#288
20160304868
2016-10-20

Compositions of asymmetric interfering RNA and uses thereof

#289
20160264981
2016-09-15

Methods and compositions for multiplex RNA guided genome editing and other RNA technologies

#290
20160264974
2016-09-15

Use of microRNA precursors as drugs for inducing CD34-positive adult stem cell expansion

#291
20160264971
2016-09-15

COMPOSITIONS AND METHODS FOR SILENCING EBOLA VIRUS GENE EXPRESSION

#292
20160257955
2016-09-08

Methods for inducing cardiomyocyte proliferation

#293
20160220525
2016-08-04

Use of novel monosaccharide-like glycylated sugar alcohol compositions for designing and developing anti-diabetic drugs

#294
20160208257
2016-07-21

AAV-based treatment of cholesterol-related disorders

#295
20160186169
2016-06-30

Effective method for specific gene silencing using artificial small RNA

#296
20160177300
2016-06-23

Means and methods for the generation of mammalian producer cells for the production of recombinant proteins

#297
20160145692
2016-05-26

Methods and compositions involving lincRNA and leukemia

#298
20160145611
2016-05-26

Age-related macular degeneration treatment

#299
20160143951
2016-05-26

Dosage compensating transgenes and cells

#300
20160135438
2016-05-19

Isolation of novel AAV's and uses thereof