112225 ⎘
Nucleic acids vectors Vector systems comprising sequences for excision in presence of a recombinase, e.g. loxP or FRT
Facultatively attenuated bacterial species and methods of preparation and use thereof
#302Reversible gene expression
#303Mouse for predicting a behavior of drugs in humans
#304Efficient protein expression in vivo using modified RNA (MOD-RNA)
#305Elimination of N-glycolylneuraminic acid from animal products for human use
#306Humanized light chain mice
#307Methods and compositions for synthesis of nucleic acid molecules using multiplerecognition sites
#308Promoter-regulated differentiation-dependent self-deleting cassette
#309Promoter-regulated differentiation-dependent self-deleting cassette
#310Multifunctional alleles
#311Animal models and therapeutic molecules
#312Synthetic regulation of gene expression
#313Substances and compositions for enhancing DNA repair and methods of use
#314Adenoviral assembly method
#315Transgenic animals and methods of use
#316Humanized universal light chain mice
#317Humanized light chain mice
#318Methods and compositions for alteration of a cystic fibrosis transmembrane conductance regulator (CFTR) gene
#319Enhanced expression and stability regions
#320Genetically modified mice having humanized TCR variable genes
#321In vivo gene regulation by the combination of knock-in-tetO sequence into the genome and tetracycline-controlled trans-suppressor (tTS) protein
#322Dopaminergic Neurons Derived From Induced Pluripotent Stem Cells and Method of Making Same
#323Mouse λ light chain locus
#324Elimination of N-glycolylneuraminic acid from animal products for human use
#325Minicircle DNA vector preparations and methods of making and using the same
#326CONDITIONAL EXPRESSION OF TRANSGENES IN VIVO
#327PHARMACOLOGICALLY INDUCED TRANSGENE ABLATION SYSTEM
#328Polycistronic vector for human induced pluripotent stem cell production
#329METHODS AND COMPOSITIONS FOR SYNTHESIS OF NUCLEIC ACID MOLECULES USING MULTIPLERECOGNITION SITES
#330ADAM6 mice
#331METHOD FOR HOMOLOGOUS RECOMBINATION IN EUKARYOTIC CELLS
#332Mouse artificial chromosome vector
#333Adenovirus library and methods
#334Chromosomal landing pads and related uses
#335CRE-LOX BASED GENE KNOCKDOWN CONSTRUCTS AND METHODS OF USE THEREOF
#336Method of producing induced pluripotent stem cells using inhibitors of P53
#337PNMT as a novel marker for progenitor cells
#338Therapeutic Antibody Target Validation and Screening In Vivo
#339Method of predicting a behavior of one or more drugs
#340FUNCTIONAL DISRUPTION OF AN IMMUNOGLOBULIN GENE IN AN AVIAN EMBRYONIC STEM CELL
#341Recombinant influenza viruses for vaccines and gene therapy
#342Methods and compositions for seamless cloning of nucleic acid molecules
#343Nucleic acids for cloning and expressing multiprotein complexes
#344Method of Genetically Altering and Producing Allergy Free Cats
#345Targeted integration into the PPP1R12C locus
#346Site-directed integration of transgenes in mammals
#347Isolation and growth of stem cells from hemangiomas
#348ISOGENIC HUMAN CELL LINES COMPRISING MUTATED CANCER ALLELES AND PROCESS USING THE CELL LINES
#349METHODS AND KITS FOR HIGH EFFICIENCY ENGINEERING OF CONDITIONAL MOUSE ALLELES
#350TRUNCATED ACTIVIN TYPE II RECEPTOR AND METHODS OF USE
#351Human artificial chromosome (HAC) vector
#352Methods for producing microRNAs
#353CHROMOSOME-BASED PLATFORMS
#354Attenuated poliovirus
#355Caveolin 1-reporter protein knock-in mouse
#356Pharmacologically induced transgene ablation system
#357Methods for Conditional and Inducible Transgene Expression to Direct the Development of Embryonic, Embryonic Stem, Precursor and Induced Pluripotent Stem Cells
#358METHOD FOR INTRODUCING MUTANT GENE, GENE HAVING MUTATION INTRODUCED THEREIN, CASSETTE FOR INTRODUCING MUTATION, VECTOR FOR INTRODUCING MUTATION, AND KNOCK-IN NON-HUMAN MAMMALIAN ANIMAL
#359Recombinant adenovirus vector having a reduced side effect
#360Non-human animal model for amyotrophic lateral sclerosis (ALS) with loss-of-TDP-43 function
#361Use of VEGF and homologues to treat neuron disorders
#362RECOMBINANT KOI HERPESVIRUS (KHV) OR CYPRINID HERPESVIRUS 3 (CYHV-3) AND A VACCINE FOR THE PREVENTION OF A DISEASE CAUSED BY KHV/CYHV-3 IN CYPRINUS CARPIO CARPIO OR CYPRINUS CARPIO KOI
#363Vectors
#364Transgenic Aves Producing Human Polyclonal Antibodies
#365Genetically modified non-human mammals and cells
#366EVERNINOMICIN BIOSYNTHETIC GENES
#367Immunoglobulin display vectors
#368FOCAL CALCIUM CHANNEL MODULATION
#369Single lentiviral vector system for induced pluripotent (iPS) stem cells derivation
#370Potential Prognostic Markers and Therapeutic Targets for Neurological Disorders
#371Method and Composition for Controlling Gene Expression
#372Targeted delivery of glycine receptors to excitable cells
#373Paramyxovirus vector encoding angiogenesis gene and use thereof
#374Recombination sequences
#375Method of generating transgenic organisms using transposons
#376TRANSGENIC ANIMALS AND METHODS OF MAKING RECOMBINANT ANTIBODIES
#377PROTEIN PRODUCTION USING EUKARYOTIC CELL LINES
#378Compositions and Systems for the Regulation of Genes
#379USE OF AAV INTEGRATION EFFICIENCY ELEMENT FOR MEDIATING SITE-SPECIFIC INTEGRATION OF A TRANSCRIPTION UNIT
#380TRANSGENIC ANIMALS EXPRESSING ANTIBODIES SPECIFIC FOR GENES OF INTEREST AND USES THEREOF
#381Method for modifying chromosomes
#382RECOMBINANT INFLUENZA VIRUSES FOR VACCINES AND GENE THERAPY
#383DEFICIENCY IN THE HISTONE DEMETHYLASE JHDM2A RESULTS IN IMPAIRED ENERGY EXPENDITURE AND OBESITY
#384SITE-SPECIFIC RECOMBINATION SYSTEMS FOR USE IN EUKARYOTIC CELLS
#385GENETICALLY MODIFIED EUKARYOTIC CELLS
#386Circular nucleic acid vectors, and methods for making and using the same
#387Multifunctional Alleles
#388knockout mice and elucidation of association of with early onset degenerative joint disease and role as a tumor suppressor
#389MUTANT MUSCLE-SPECIFIC ENHANCERS
#390Mouse λ light chain locus
#391DEVELOPMENT STAGE-SPECIFIC LETHALITY SYSTEM FOR INSECT POPULATION CONTROL
#392SYSTEM FOR PACKAGING HIGH-CAPACITY ADENOVIRUSES
#393Reprogramming of somatic cells
#394SELF-INACTIVATING HELPER ADENOVIRUSES FOR THE PRODUCTION OF HIGH-CAPACTIY RECOMBINANT ADENOVIRUSES
#395Expression of Xenogenous (Human) Immunoglobulins in cloned, transgenic ungulates
#396Methods of inhibiting tumor cell proliferation
#397VECTORS AND METHODS FOR GENERATING VECTOR-FREE INDUCED PLURIPOTENT STEM (IPS) CELLS USING SITE-SPECIFIC RECOMBINATION
#398Methods and compositions for targeted gene modification
#399TRANSGENIC MAMALS MODIFIELD IN BRI PROTEIN EXPRESSION
#400METHODS AND COMPOSITIONS FOR SEAMLESS CLONING OF NUCLEIC ACID MOLECULES
#401Substances and compositions for enhancing DNA repair and methods of use
#402Promoter-regulated differentiation-dependent self-deleting cassette
#403miRNA-regulated differentiation-dependent self-deleting cassette
#404Animal model, and products and methods useful for the production thereof
#405Compositions and methods modulating MG29 for the treatment of diabetes
#406Truncated activin type II receptor and methods of use
#407Production of viral vectors
#408Everninomicin biosynthetic genes
#409Targeted integration into stem cells
#410Functional Disruption Of Avian Immunoglobulin Genes
#411GENETIC REFERENCE MATERIALS
#412Methods and materials for the reproducible generation of high producer cell lines for recombinant proteins
#413METHOD OF PREPARING INDUCED PLURIPOTENT STEM CELLS DEPRIVED OF REPROGRAMMING GENE
#414Methods of using human tissue factor-producing knock-in mice
#415Methods of protein production using ovomucoid regulatory regions
#416Animal Model Based on Targeted Apoptosis for the Study of Genetic Diseases Such as Parkinson's Disease
#417Transgenic non-human animals for pharmacological and toxicological studies
#418Compositions and methods for monosynaptic transport
#419VECTORS WITH MODIFIED PROTEASE-DEPENDENT TROPISM
#420Transgenic mouse with a homozygous mutation in the CMAH gene
#421Enhanced expression and stability regions
#422A CONSERVED REGION OF THE HIV-1 GENOME AND USES THEREOF
#423Compositions and methods for making therapies delivered by viral vectors reversible for safety and allele-specificity
#424Modified transposon vector and its use
#425Oncolytic virus
#426ENHANCED HOMOLOGOUS RECOMBINATION MEDIATED BY LAMBDA RECOMBINATION PROTEINS
#427AIDS virus vaccines using Sendai virus vector
#428Properdin Modulation of Alternative Pathway and Uses Thereof
#429Methods of identifying small molecules for renewals, survival and migration of cardiac progenitors
#430COMPOSITIONS AND METHODS FOR HEMATOPOIETIC STEM CELL EXPANSION OR FOR MODULATING ANGIOGENESIS
#431OPTIMIZED T-DNA TRANSFER AND VECTORS THEREFOR
#432IDENTIFICATION OF GROUP OF HYPERTENSION-SUSCEPTIBILITY GENES
#433ATTENUATED INVASIVE E.COLI STRAINS AND APPLICATIONS THEREOF AS INTRACELLULAR VECTOR FOR THERAPEUTIC MOLECULE
#434Enhancer-containing gene trap vectors for random and targeted gene trapping
#435Regulation of expression of PI3Kβ protein in tumors
#436Altered Recombinases for Genome Modification
#437In vivo genome-wide mutagenesis
#438Tunable genetic switch for regulating gene expression
#439METHODS OF GENERATING CARDIOMYOCYTES
#440Use of tailored recombinases for the treatment of retroviral infections
#441PARAMYXOVIRUS VECTOR ENCODING ANGIOGENESIS GENE AND USE THEREOF
#442Pig whose genome comprises a heterologous site-specific recombination site and a transpohon tag
#443Polycistronic Vector For Human Induced Pluripotent Stem Cell Production
#444Compositions and Methods for Modulating Cognitive Function
#445Method for producing a transgenic pig using a hyper-methylated transposon
#446TRANSGENIC NON-HUMAN ANIMAL
#447Reduction of graft-versus-host disease by modulation of SHIP activity
#448Pluripotency determining factors and uses thereof
#449Transgenic chickens with an inactivated endogenous gene locus
#450IDENTIFICATION OF GROUP OF HYPERTENSION-SUSCEPTIBILITY GENES
#451Transgenic pig as a model of Alzheimer's disease
#452Pig model for atherosclerosis
#453Detection of cellular stress
#454Method of stimulating epithelial cell proliferation by administration of gastrointestinal proliferative factor
#455Method for transcription/degradation dual control of protein by antibiotic
#456HUMANISATION OF ANIMALS
#457PIG MODEL FOR PSORIASIS
#458METHOD FOR HOMOLOGOUS RECOMBINATION
#459Methods for Conditional and Inducible Transgene Espression to Direct the Development of Embryonic, Embryonic Stem, Precursor and Induced Pluripotent Stem Cells
#460PIG MODEL FOR BREAST CANCER, MITOCHONDRIA RELATED PROTEIN FOLDING DISORDERS AND/OR EPIDERMOLYSIS BULLOSA SIMPLEX
#461Double-muscling in mammals
#462Method of adenoviral vector synthesis
#463METHODS AND REAGENTS FOR SCREENING NEW DRUGS AND FOR TREATING ION PUMP ASSOCIATED DISORDERS AND DISEASES
#464Isolated polynucleotides, nucleic acid constructs, methods and kits for localization of rna and/or polypeptides within living cells
#465Production of heterologous protein in the avian oviduct
#466Ungulates with genetically modified immune systems
#467Animal model exhibiting cancer, pulmonary emphysema and cardiomyopathy
#468Minicircle DNA vector preparations and methods of making and using the same
#469Animal having modification in MGAT2 gene
#470SITE-SPECIFIC RECOMBINATION SYSTEMS FOR USE IN EUKARYOTIC CELLS
#471Transgenic non-human animals expressing a truncated activin type II receptor
#472Methods to generate DNA mini-circles
#473High efficiency FLP site-specific recombination in mammalian cells using an optimized FLP gene
#474KNOCKOUT ANIMAL EXHIBITING ANXIETY-LIKE BEHAVIOR
#475Methods for preparing mature erythrocytes from conditionally immortalized hematopoietic stem cells
#476Use of VEGF and homologues to treat neuron disorders
#477Method for sustained expression of an exogenous gene
#478Compositions comprising MG29 nucleic acids, polypeptides, and associated methods of use
#479Prostate Epithelial Androgen Receptor Suppresses Prostate Growth and Tumor Invasion
#480Compositions and Methods for Modulating Osteoblast Cell Differentiation and Bone Generation Through HIF-1a
#481Targeting the Rosa26 gene in human embryonic stem cells
#482Human artificial chromosome (HAC) vector and human cell medicine comprising same
#483CHIMERIC NON-HUMAN ANIMAL
#484ISOLATION OF THE T-COMPLEX DISTORTERS AND APPLICATIONS THEREOF
#485DNA Vector Production System
#486Novel apoptosis inducing factor and method of inducing apoptosis using the same
#487Use of Caspase-8 Inhibitors for Modulating Hematopoiesis
#488SGRF gene-modified mouse
#489TRANSGENIC ANIMALS WITH REDUCED MAJOR URINARY PROTEIN PRODUCTION
#490ABI1 conditional knockout mouse
#491METHOD FOR REMOVING DESIRED CHROMOSOME AND TAILOR-MADE MEDICAL TREATMENT UTILIZING THE SAME
#492Isolated human chromosome 14 fragment encoding immunoglobulin genes
#493RECOMBINANT INFLUENZA VIRUSES FOR VACCINES AND GENE THERAPY
#494Attenuated poliovirus
#495Transgenic non-human animals for pharmacological and toxicological studies
#496Gene recombination exchange system for stable gene modification in human ES cells
#497Antibodies produced in a transgenic avian egg white
#498Enzymes, cells and methods for site specific recombination at asymmetric sites
#499Cre-lox based gene knockdown constructs and methods of use thereof
#500Inflammation models in neurodegenerative and arthritic disorders
#501Methods for Controlling Stem Cell Differentiation
#502Compositions and Methods Related to Controlled Gene Expression Using Viral Vectors
#503Genetically modified non-human mammals and cells
#504In vivo transfection in avians
#505Conditional-stop dimerizable caspase transgenic animals
#506Cre-lox based gene knockdown constructs and methods of use thereof
#507Truncated Activin Type II Receptor and Methods of Use
#508Composition and method for imaging cells
#509Mouse carrying a knock-out mutation of the Qpct-gene
#510Methods and protein production using ovomucoid promoters
#511Highly safe intranasally administrable gene vaccines for treating alzheimer's disease
#512METHOD FOR HOMOLOGOUS RECOMBINATION IN EUKARYOTIC CELLS
#513Transgenic bovine having reduced prion protein activity and uses thereof
#514Chimeric Non-Human Animal and Use Thereof
#515Recombinant adenoviruses preparation and adenovirus banks
#516Method for Gene Amplification
#517Reversibly immortalized mammalian liver cells and use thereof
#518Vectors capable of immortalizing non-dividing cells and cells immortalized with said vectors
#519Immunoglobulin display vectors
#520HBM variants that modulate bone mass and lipid levels
#521METHOD FOR HOMOLOGOUS RECOMBINATION IN FUNGAL CELLS
#522Enhanced expression and stability regions
#523Ex vivo and in vivo expression of the thrombomodulin gene for the treatment of cardiovascular and peripheral vascular diseases
#524GENE TRAP CASSETTES FOR RANDOM AND TARGETED CONDITIONAL GENE INACTIVATION
#525Protein and peptide fragments from mouse telomerase reverse transcriptase
#526Ex vivo and in vivo expression of the thrombomodulin gene for the treatment of cardiovascular and peripheral vascular diseases
#527NOVEL RECOMBINANT ADENOVIRUS VECTOR HAVING A REDUCED SIDE EFFECT
#528Targeting constructs for the functional disruption of avian immunoglobulin genes
#529Methods for producing microRNAs
#530PREMATURELY AGEING MOUSE MODELS FOR THE ROLE OF DNA DAMAGE IN AGEING AND INTERVENTION IN AGEING-RELATED PATHOLOGY
#531PNMT as a novel marker for progenitor cells
#532Methods and compositions for genomic modification
#533Compositions and methods for studying and treating inflammatory diseases and disorders
#534Transgenic animal model of bone mass modulation
#535High-efficiency wild-type-free AAV helper functions
#536Transgenic Animals for Assessing Drug Metabolism and Toxicity in Man
#537Method for modifying chromosomes
#538Everninomicin biosynthetic genes
#539RECOMBINASE-EXPRESSING CELLS
#540Human artificial chromosome containing human antibody λ light chain gene and non-human animal containing the human artificial chromosome capable of genetic transmission
#541Role of alpha1-adrenergic receptors
#542Gastrointestinal proliferative factor and uses thereof
#543Vectors with modified protease-dependent tropism
#544Targeted integration into the PPP1R12C locus
#545ISOLATION AND GROWTH OF STEM CELLS FROM HEMANGIOMAS
#546Tumor mouse models using lentiviral vectors
#547Targeted delivery of glycine receptors to excitable cells
#548Soluble Hybrid Prion Proteins And Their Use In The Diagnosis, Prevention And Treatment Of Transmissible Spongiform Encephalopathies
#549Recombinant Adenovirus Expressing A Gene Encoding Streptolysin O Proetin and Anti-Cancer Composition Comprising Same
#550Non-invasive real-time in vivo bioluminescence imaging of local Ca+ dynamics in living organisms
#551Baculovirus-Based Gene Libraries
#552Ant2 Conditional Knockout Mouse and Methods
#553Genetic manipulation method
#554Animal models of pancreatic adenocarcinoma and uses therefor
#555Methods and compositions for synthesis of nucleic acid molecules using multiple recognition sites
#556Targeting of sall4 for the treatment and diagnosis of proliferative disorders associated with myelodysplastic syndrome (MDS)
#557Transgenic animal model
#558Dampening Humoral and Innate Immunity by Inhibition of Ppgalnact-1
#559Polypeptide, novel DNA and novel antibody
#560Vectors having both isoforms of beta-hexosaminidase and uses of the same
#561In vivo transfection in avians
#562Transgenic non-human animal for use in research models for studying Parkinson's disease
#563Vectors and Methods Using Same
#564Animal model for cancer, methods of producing the same and associated methods of use
#565Siv and Hiv Vaccination Using Rhcmv- and Hcmv-Based Vaccine Vectors
#566Transgenic Animals and Methods of Making Recombinant Antibodies
#567Method of generating transgenic organisms using transposons
#568Compositions and methods for monosynaptic transport
#569Herpes Virus-Based Compositions and Methods of Use
#570Suppression of Endogenous Immunoglobulin Expression in Non-Human Transgenic Animals
#571Procedure for specific replacement of a copy of a gene present in the recipient genome by the integration of a gene different from that where the integration is made
#572Focal calcium channel modulation
#573Altered Recombinases for Genome Modification
#574Culturing human cells and tissues in an N-glycolylneuraminic acid-free environment
#575Chromosomal loci for the stringent control of gene activities via transcription activation systems
#576Adenovirus particles with enhanced infectivity of dendritic cells and particles with decreased infectivity of hepatocytes
#577Method for the Generation of Virus Producing Cell Lines and Cell Lines
#578Methods And Compositions For Combinatorial Approaches To Cancer Gene Therapy
#579Methods of identifying small molecules for renewal, survival and migration of cardiac progenitors
#580Stable Genomic Integration of Multiple Polynucleotide Copies
#581Control of NK cell function and survival by modulation of SHIP activity
#582Mouse model of chronic heart failure and coronary atherosclerosis regression
#583Modified Cells and Methods of Using Same
#584Mouse model of cholinergic dysfunction to evaluate cognitive enhancers and drugs that improve myasthenia
#585Optimized T-DNA transfer and vectors therefor
#586Genetic Reference Materials
#587Use of VEGF and homologuest to treat neuron disorders
#588Method of proliferation in neurogenic regions
#589Methods and compositions for identifying biomarkers
#590Ungulates with genetically modified immune systems
#591Transgenic mice carrying functional single nucleotide polymorphisms in brain-specific tryptophan hydroxylase
#592New Expression Tools for Multiprotein Applications
#593Methods And Compositions Involving S-Ship Promoter Regions
#594Animal model for identifying agents that inhibit or enhance CTLA4 signaling
#595Method for Producing Non-Pathogenic Helper Virus-Free Preparations of Herpes Virus Amplicon Vectors, the Helper Virus and the Cells Used in this Method, the Corresponding Generic Tools, as Well as the Applications of These Non-Pathogenic Amplicon Vectors
#596Transgenic mouse comprising a polynucleotide encoding human or humanized C5aR and methods of production and use
#597Methods of Identifying Compounds Which Modulate Granulocite-Colony Stimulating Factor (G-Csf) Dependent Processes by Modulation of the Levels of Suppressor of Cytokine Signaling (Socs)
#598Methods of modifying genes in eukaryotic cells
#599Tumor-Specific Expression of Reporter Genes
#600Use of Caspase-8 Inhibitors for Modulating Hematopoiesis