112284 ⎘
Vector systems having a special element relevant for transcription controllable enhancer/promoter combination inducible enhancer/promoter combination, e.g. hypoxia, iron, transcription factor
Engineered dendritic cells and uses for the treatment of cancer
#302FROG/TOAD conditionally silenced vectors for hypoxia gene therapy
#303Minicircle DNA vector preparations and methods of making and using the same
#304PHARMACOLOGICALLY INDUCED TRANSGENE ABLATION SYSTEM
#305Promoters exhibiting endothelial cell specificity and methods of using same for regulation of angiogenesis
#306USE OF MEGANUCLEASES FOR INDUCING HOMOLOGOUS RECOMBINATION EX VIVO AND IN TOTO IN VERTEBRATE SOMATIC TISSUES AND APPLICATION THEREOF
#307USE OF MEGANUCLEASES FOR INDUCING HOMOLOGOUS RECOMBINATION EX VIVO AND IN TOTO IN VERTEBRATE SOMATIC TISSUES AND APPLICATION THEREOF
#308Ecdysone receptor-based inducible gene expression system
#309Use of meganucleases for inducing homologous recombination ex vivo and in toto in vertebrate somatic tissues and application thereof
#310Hepatocyte Based Insulin Gene Therapy For Diabetes
#311USE OF MEGANUCLEASES FOR INDUCING HOMOLOGOUS RECOMBINATION EX VIVO AND IN TOTO IN VERTEBRATE SOMATIC TISSUES AND APPLICATION THEREOF
#312Regulation of endogenous gene expression in cells using zinc finger proteins
#313USE OF MEGANUCLEASES FOR INDUCING HOMOLOGOUS RECOMBINATION EX VIVO AND IN TOTO IN VERTEBRATE SOMATIC TISSUES AND APPLICATION THEREOF
#314USE OF MEGANUCLEASES FOR INDUCING HOMOLOGOUS RECOMBINATION EX VIVO AND IN TOTO IN VERTEBRATE SOMATIC TISSUES AND APPLICATION THEREOF
#315Use of meganucleases for inducing homologous recombination ex vivo and in toto in vertebrate somatic tissues and application thereof
#316CONTROL OF GENE EXPRESSION
#317Promoter sequences
#318Transgenic non-human animal and uses thereof
#319Method and Composition to Increase Radiation-Induced Tumor Therapeutic Effects
#320CRE-LOX BASED GENE KNOCKDOWN CONSTRUCTS AND METHODS OF USE THEREOF
#321Promoters exhibiting endothelial cell specificity and methods of using same
#322Targeted cell death
#323Stem cell beacon
#324CUSTOM-MADE MEGANUCLEASE AND USE THEREOF
#325Synthetic genes and genetic constructs
#326Engineered biological pacemakers
#327THERAPEUTIC REGIMEN FOR TREATING CANCER
#328Engineered Dendritic Cells and Uses for the Treatment of Cancer
#329TRUNCATED ACTIVIN TYPE II RECEPTOR AND METHODS OF USE
#330Simian adenovirus nucleic acid and amino acid sequences, vectors containing same, and methods of use
#331Genetically modified mesenchymal stem cell that express an exogenous cytotoxic protein
#332Materials and methods for the treatment of pathological neovascularization in the eye
#333Pharmacologically induced transgene ablation system
#334Gene delivery system and method of use
#335Controlling transgene expression across the skin
#336Expression Vector
#337ShRNA gene therapy for treatment of ischemic heart disease
#338POLYPEPTIDES AND POLYNUCLEOTIDES ENCODING SAME AND USE THEREOF IN THE TREATMENT OF MEDICAL CONDITIONS ASSOCIATED WITH ISCHEMIA
#339Optogenetic method for generating an inhibitory current in a mammalian neuron
#340Method for suppressing cell growth
#341Use of VEGF and homologues to treat neuron disorders
#342Multi-chain eukaryotic display vectors and uses thereof
#343Use of meganucleases for inducing homologous recombination ex vivo and in toto in vertebrate somatic tissues and application thereof
#344Multi-chain eukaryotic display vectors and uses thereof
#345Multi-chain eukaryotic display vectors and uses thereof
#346Attentuated Herpesvirus Encoding a Mek Pathway Polypeptide
#347Modified Thromboxane A2 Receptor Promoter Sequence
#348COMPOSITIONS AND METHODS FOR REGULATING CELL OSMOLARITY
#349Engineered cells expressing multiple immunomodulators and uses thereof
#350Regulation of endogenous gene expression in cells using zinc finger proteins
#351Isolated transgenic mammalian neural cell for detection of a sample containing a chemical substance damage to neurological system or selection of drugs for treating neurodegenerative disorders
#352Transgenic fish and uses thereof
#353PROMOTERS EXHIBITING ENDOTHELIAL CELL SPECIFICITY AND METHODS OF USING SAME FOR REGULATION OF ANGIOGENESIS
#354PROMOTERS EXHIBITING ENDOTHELIAL CELL SPECIFICITY AND METHODS OF USING SAME
#355Multi-chain eukaryotic display vectors and uses thereof
#356NUCLEIC ACIDS, BACTERIA, AND METHODS FOR DEGRADING THE PEPTIDOGLYCAN LAYER OF A CELL WALL
#357USE OF MEGANUCLEASES FOR INDUCING HOMOLOGOUS RECOMBINATION EX VIVO AND IN TOTO IN VERTEBRATE SOMATIC TISSUES AND APPLICATION THEREOF
#358Viral vectors whose replication and, optionally, passenger gene are controlled by a gene switch activated by heat in the presence or absence of a small-molecule regulator
#359Promoters exhibiting endothelial cell specificity and methods of using same for regulation of angiogenesis
#360Circular nucleic acid vectors, and methods for making and using the same
#361Translation enhancer-element dependent vector systems
#362Modified Nucleotide Sequence Encoding Glucagon-Like Peptide-1 (GLP-1), Nucleic Acid Construct Comprising Same for Production of Glucagon-Like Peptide-1 (GLP-1), Human Cells Comprising Said Construct and Insulin-Producing Constructs, and Method of Use Thereof
#363Novel Ecdysone Receptor-Based Inducible Gene Expression System
#364Ecdysone receptor-based inducible gene expression system
#365Recombinant Double-Stranded RNA Phage, and Use of the Same
#366THERAPEUTIC REGIMEN FOR TREATING CANCER
#367Truncated activin type II receptor and methods of use
#368Production of viral vectors
#369DNA fragment and use thereof
#370Antibody-producing transgenic silkworms and methods for producing the same
#371NEW MODULATING MOLECULES FOR AN IMPROVED REGULATED EXPRESSION SYSTEM
#372Hypoxia inducible VEGF plasmid for ischemic disease
#373Multi-chain eukaryotic display vectors and uses thereof
#374TARGETED CELL DEATH
#375POLYPEPTIDES AND POLYNUCLEOTIDES ENCODING SAME AND USE THEREOF IN THE TREATMENT OF MEDICAL CONDITIONS ASSOCIATED WITH ISCHEMIA
#376Promoter inducible by reactive oxygen species and vector comprising the same
#377Engineered cellular pathways for programmed autoregulation of differentiation
#378Promoters Exhibiting Endothelial Cell Specificity and Methods of Using Same for Regulation of Angiogenesis
#379Alteration of tumor growth using zinc finger proteins
#380Model animal in which state of disease condition is observable in real time, gene construct for achieving the same and use of the same
#381LexA-based chemical-inducible gene expression system for use in transgenic animals
#382ENHANCED HOMOLOGOUS RECOMBINATION MEDIATED BY LAMBDA RECOMBINATION PROTEINS
#383Regulation of endogenous gene expression in cells using zinc finger proteins
#384INFLAMMATION-INDUCED ANTI-FLAMMATORY GENE EXPRESSION
#385Coumermycin/novobicin-regulated gene expression system
#386DNA for eukaryotic expression of CymR
#387Eukaryotic layered vector initiation systems
#388Ligand-regulable transactivation systems, methods of use thereof, methods of detecting estrogen receptor ligands, and methods of differentiating estrogen receptor ligand agonists and antagonists
#389ENDOCRINE CELL LINES AND METHOD OF USING THE SAME
#390TARGETED TUMOR THERAPY BY USE OF RECOMBINANT ADENOVIRUS VECTORS THAT SELECTIVELY REPLICATE IN HYPOXIC REGIONS OF TUMORS
#391REGULATED EXPRESSION OF RECOMBINANT PROTEINS FROM ADENO-ASSOCIATED VIRAL VECTORS
#392VECTORS AND METHODS FOR ENZYME PRODUCTION
#393Use of meganucleases for inducing homologous recombination ex vivo and in toto in vertebrate somatic tissues and application thereof
#394In Vivo Production and Delivery of Erythropoietin or Insulinotropin for Gene Therapy
#395ISOLATED DNA FRAGMENT OF THE HUMAN A33 PROMOTER AND ITS USE TO CONTROL THE EXPRESSION OF A HETEROLOGOUS GENE IN TUMOR CELLS
#396Nucleic acid for treatment or prevention of immunodeficiency virus infection
#397Promoters exhibiting endothelial cell specificity and methods of using same for regulation of angiogenesis
#398Minicircle DNA vector preparations and methods of making and using the same
#399Transgenic non-human animals expressing a truncated activin type II receptor
#400Use of VEGF and homologues to treat neuron disorders
#401Restoration of visual responses by in vivo delivery of rhodopsin nucleic acids
#402Promoters exhibiting endothelial cell specificity and methods of using same
#403Recombinant vector for deleting specific regions of chromosome and method for deleting specific chromosomal regions of chromosome in the microorganism using the same
#404Recombinant double stranded RNA nucleocapsid and use of the same
#405Steroidal ligands and their use in gene switch modulation
#406Adenovirus vectors specific for cells expressing androgen receptor and methods of use thereof
#407Gene therapy for amyotrophic lateral sclerosis and other spinal cord disorders
#408Expression system for proteins
#409Methanol-responsive promoter, fusion gene comprising promoter and foreign gene connected so that foreign gene can be expressed, vector, transformant, and method of producing protein
#410Pseudotyped retroviral vectors and methods of use thereof
#411Cre-lox based gene knockdown constructs and methods of use thereof
#412Inflammation models in neurodegenerative and arthritic disorders
#413Truncated Activin Type II Receptor and Methods of Use
#414Use of the ornithine transcarbamylase (), as a marker for diagnosing brain damages
#415ENRICHED PREPARATION OF HUMAN FETAL MULTIPOTENTIAL NEURAL STEM CELLS
#416Adenoviral vector-based malaria vaccines
#417Therapeutic Gene-Switch Constructs and Bioreactors for the Expression of Biotherapeutic Molecules, and Uses Thereof
#418Adenovirus vectors containing cell status-specific response elements and methods of use thereof
#419Engineered Dendritic Cells and Uses for the Treatment of Cancer
#420Multiple Heat Shock Elements
#421Ligand screening and discovery
#422SYSTEMS, METHODS AND COMPOSITIONS FOR OPTICAL STIMULATION OF TARGET CELLS
#423Methods of Identifying Synthetic Transcriptional and Translational Regulatory Elements, and Compositions Related to Same
#424REGULATABLE FUSION PROMOTERS
#425Compositions and methods for studying and treating inflammatory diseases and disorders
#426Targeted cell death
#427Viral vectors whose replication and, optionally, passenger gene are controlled by a gene switch activated by heat in the presence or absence of a small-molecule regulator
#428TRANSGENIC ORGANISM
#429Modified nucleotide sequence encoding glucagon-like peptide-1 (GLP-1), nucleic acid construct comprising same for production of glucagon-like peptide-1 (GLP-1), human cells comprising said construct and insulin-producing constructs, and methods of use thereof
#430Polynucleotides and Polypeptides of the IFNalpha-21 Gene
#431heat inducible promoters and their use
#432Sequential delivery of immunogenic molecules via adenovirus and adeno-associated virus-mediated administrations
#433Transgenic animal model
#434DIACYLHYDRAZINE LIGANDS FOR MODULATING THE EXPRESSION OF EXOGENOUS GENES IN MAMMALIAN SYSTEMS VIA AN ECDYSONE RECEPTOR COMPLEX
#435Vectors for tissue-specific replication
#436Means and methods for producing adenovirus vectors
#437Diacylhydrazine ligands for modulating the expression of exogenous genes in mammalian systems via an ecdysone receptor complex
#438Adenovirus vectors containing cell status-specific response elements and methods of use thereof
#439Adenovirus vectors containing cell status-specific response elements and methods of use thereof
#440METHOD FOR DETERMINING GENOTOXICITY
#441Compositions and methods for modulating hedgehog signaling
#442Anemia
#443Adenovirus particles with enhanced infectivity of dendritic cells and particles with decreased infectivity of hepatocytes
#444Ecdysone receptor-based inducible gene expression system
#445Diacylhydrazine ligands for modulating the expression of exogenous genes in mammalian systems via an ecdysone receptor complex
#446Vectors for tissue-specific replication
#447Simian adenovirus nucleic acid and amino acid sequences, vectors containing same, and methods of use
#448Devices, vectors and methods for inducible ischemia cardioprotection
#449Adenovirus vectors containing cell status-specific response elements and methods of use thereof
#450Vectors for tissue-specific replication
#451Transgenic flies expressing tau and amyloid precursor fragment
#452System for regulated and enhanced baculovirus mediated transient transgene expression in mammalian cells
#453Ligand-regulable transactivation systems, methods of use thereof, methods of detecting estrogen receptor ligands, and methods of differentiating estrogen receptor ligand agonists and antagonists
#454Use of VEGF and homologuest to treat neuron disorders
#455Integration-type low-dose radiation-inducible vector
#456Vector and method for detecting the change in transcription amount
#457Regulated expression of recombinant proteins from adeno-associated viral vectors
#458Method for Producing Non-Pathogenic Helper Virus-Free Preparations of Herpes Virus Amplicon Vectors, the Helper Virus and the Cells Used in this Method, the Corresponding Generic Tools, as Well as the Applications of These Non-Pathogenic Amplicon Vectors
#459Treatment of diabetes with synthetic beta cells
#460Tumor-Specific Expression of Reporter Genes
#461Methods of identifying synthetic transcriptional and translational regulatory elements, and compositions relating to same
#462Use of VEGF and homologues to treat neuron disorders
#463Novel Herpes Simplex Viruses
#464Stem Cell Beacon
#465Transgenic animals and methods of monitoring hedgehog responding cells
#466Methods and compositions relating to restricted expression lentiviral vectors and their applications
#467Zebrafish models of acute myelogenous leukemia
#468Substrates for beta-lactamase and uses thereof
#469GM-CSF gene therapy for Crohn's disease using an improved regulated expression system
#470Adenovirus-transfected primary cells and methods of pathway mapping
#471Ecdysone receptor-based inducible gene expression system
#472Hypoxia inducible VEGF plasmid for ischemic disease
#473Method for selective expression of therapeutic genes by hyperthermia
#474Hiv-dependent expression constructs and uses therefor
#475Method for producing immortalised antibodies-secreting cells
#476Vigilant cells
#477Endocrine cell lines and methods of using same
#478Orthogonal gene switches
#479Vectors for tissue-specific replication
#480Production of recombinant AAV using adenovirus comprising AAV rep/cap genes
#481Artificial chromosomes, uses thereof and methods for preparing artificial chromosomes
#482Translation enhancer-element dependent vector systems
#483Tarp promoter and uses thereof
#484Polynucleotides for use in recombinant adeno-associated virus virion production
#485Coumermycin/novobiocin-regulated gene expression system
#486Combinatorial expression of split caspase molecules
#487Inhibition of Lysyl oxidase for treating tumor growth and diagnostics relating thereto
#488Glucose inducible insulin expression and methods of treating diabetes
#489Interferon-beta gene therapy using an improved, regulated expression system
#490Regulation of endogenous gene expression in cells using zinc finger proteins
#491Treatment of disease using an improved regulated expression system
#492Repressing endogenous CCR5 gene expression in cells using engineered zinc finger proteins
#493Recombinant double-stranded RNA phage, and use of the same
#494Therapeutic regimen for treating cancer
#495Inducible plasmid vector encoding TGF-β and use thereof
#496Directed complementation
#497Circular nucleic acid vectors, and methods for making and using the same
#498Directed complementation
#499Tr2, tr4, tr2/tr4 double knockouts and uses thereof
#500Non-naturally occurring animal that expresses an untranslated non-coding RNA
#501Transposon-based vectors and methods of nucleic acid integration
#502Custom-made meganuclease and use thereof
#503Promoters exhibiting endothelial cell specificity and methods of using same for regulation of angiogenesis
#504Adenovirus vectors containing cell status-specific response elements and methods of use thereof
#505Regulatable gene expression in mammalian cells and mammals
#506Enhancers specific to motor nerve cells/sensory nerve cells
#507Use of meganucleases for inducing homologous recombination ex vivo and in toto in vertebrate somatic tissues and application thereof
#508Enhancement of adenoviral oncolytic activity by modification of the E1A gene product
#509Recombinant double-stranded RNA phages and uses thereof
#510Selective inhibition of rock1 in cardiac therapy
#511Packaging of positive-strand RNA virus replicon particles
#512Sex-specific automated sorting of non-human animals
#513Inducible eukaryotic expression system
#514Targeted tumor therapy by use of recombinant adenovirus vectors that selectively replicate in hypoxic regions of tumors
#515RNA silencing in animals as an antiviral defense
#516Regulation of endogenous gene expression in cells using zinc finger proteins
#517Highly hypoxia-specific gene expression system for ischemic gene therapy
#518Compositions and methods for protein production
#519Gene transcription and ionizing radiation: methods and compositions
#520Chimeric viral vectors for gene therapy
#521Target cell-specific adenoviral vectors containing E3 and methods of use thereof
#522Selective killing of cancerous cells
#523Hyperthermic inducible expression vectors for gene therapy and methods of use thereof
#524Control of gene expression
#525Methods for modulating expression of exogenous genes in mammalian systems, and products related thereto
#526Vectors having both isoforms of beta-hexosaminidase
#527Promiscuous G-protein compositions and their use
#528Vectors for tissue-specific replication
#529Induction of apoptic or cytotoxic gene expression by adenoviral mediated gene codelivery
#530Molecular switch for regulating mammalian gene expression
#531Method to improve translation of polypeptides by using untranslated regions from heat-shock proteins
#532Treatment of diabetes with synthetic beta cells
#533Transgenic non-human animals expressing a truncated activin type II receptor
#534Control of gene expression
#535Compositions and methods for gene silencing
#536Control of gene expression in eukaryotic cells
#537Regulation of endogenous gene expression in cells using zinc finger proteins
#538Diaclhydrazine ligands for modulating the expression of exogenous genes in mammalian systems via an ecdysone receptor complex
#539Methods of unidirectional, site-specific integration into a genome, compositions and kits for practicing the same
#540Methods for detecting metalloproteinase inhibitors
#541Molecular regulatory circuits to achieve sustained activation of genes of interest by a single stress
#542Promoters exhibiting endothelial cell specificity and methods of using same for regulation of angiogenesis
#543Adenovirus vectors containing cell status-specific response elements and methods of use thereof
#544Hyperthermic inducible expression vectors for gene therapy and methods of use thereof
#545Means and methods for the production of adenovirus vectors
#546Antigen presenting system and methods for activation of T-cells
#547In vivo production and delivery of erythropoietin or insulinotropin for gene therapy
#548Viral vectors whose replication and, optionally, passenger gene are controlled by a gene switch activated by heat in the presence or absence of a small molecule regulator
#549Regulation of endogenous gene expression in cells using zinc finger proteins
#550DNA construct for effecting homologous recombination and uses thereof
#551Anemia
#552Packaging complementation cell-line for sv-40 vectors
#553Generation of recombinant adeno-associated viral vectors by a complete adenovirus-mediated approach
#554Method for identifying target epitopes of the T cell mediated immune response and for assaying epitope-specific T cells
#555Promoters exhibiting endothelial cell specificity and methods of using same
#556Methods of treating diabetes and other blood sugar disorders
#557Viruses targeted to hypoxic cells and tissues
#558Simian adenovirus nucleic acid and amino acid sequences, vectors containing same, and methods of use
#559Spatial and temporal control of gene expression using a heat shock protein promoter in combination with local heat
#560Specific proliferation in tumour cell which can express antioncogene with high efficiency and the use of it
#561Use of chimeric nucleases to stimulate gene targeting
#562Diminishing viral gene expression by promoter replacement
#563Retroviral vectors comprising a functional splice donor site and a functional splice acceptor site
#564Gene delivery system and methods of use
#565Microorganisms and methods for producing biologics and introducing biologics to sites