112282 ⎘
Vector systems having a special element relevant for transcription
Sub-classes:NUCLEIC ACID CONSTRUCT AND USE THEREOF
#2TUMOR-SELECTIVE E1A AND E1B MUTANTS
#3TAT-INDUCED CRISPR/ENDONUCLEASE-BASED GENE EDITING
#4Riboswitch modulated gene therapy for retinal diseases
#5IMMUNOGENIC COMPOSITION
#6RIBOSWITCH MODULATED GENE THERAPY FOR RETINAL DISEASES
#7METHODS TO PROTECT TRANSPLANTED TISSUE FROM REJECTION
#8RECOMBINANT ADENO-ASSOCIATED VIRUS VECTORS WITH CD14 PROMOTER AND USE THEREOF
#9ARTIFICIAL NUCLEIC ACID MOLECULES
#10Tumor-selective E1a and E1b mutants
#11Orthogonal Cas9 Proteins for RNA-Guided Gene Regulation and Editing
#12NUCLEIC ACID MOLECULE FOR TREATING THROMBOCYTOPENIA AND APPLICATION THEREOF
#13TAT-INDUCED CRISPR/ENDONUCLEASE-BASED GENE EDITING
#14COMPOSITIONS AND METHODS FOR REDUCING NUCLEASE EXPRESSION AND OFF-TARGET ACTIVITY USING A PROMOTER WITH LOW TRANSCRIPTIONAL ACTIVITY
#15Endothelium-Specific Nucleic Acid Regulatory Elements and Methods and Use Thereof
#16RECOMBINANT HEME THIOLATE OXYGENASES
#17CHIMERIC GENE CONSTRUCTS FOR GENERATION OF FLUORESCENT TRANSGENIC ORNAMENTAL FISH
#18Recombinant adeno-associated virus vectors with CD14 promoter and use thereof
#19A CELL SURFACE TAG EXCHANGE (CSTE) SYSTEM FOR TRACING AND MANIPULATION OF CELLS DURING RECOMBINASE MEDIATED CASSETTE EXCHANGE INTEGRATION OF NUCLEIC ACID SEQUENCES TO ENGINEERED RECEIVER CELLS
#20ADENO-ASSOCIATED VIRUS COMPOSITIONS FOR IDS GENE TRANSFER AND METHODS OF USE THEREOF
#21FOWL ADENOVIRUS 9 (FADV-9) VECTOR SYSTEM AND ASSOCIATED METHODS
#22Tumor-selective E1A and E1B mutants
#23Compositions and Methods for Multiplexed Genome Editing and Screening
#24Replication-enhanced oncolytic adenoviruses
#25Modified promoter
#26EXPRESSION VECTOR ELEMENT COMBINATIONS, NOVEL PRODUCTION CELL GENERATION METHODS AND THEIR USE FOR THE RECOMBINANT PRODUCTION OF POLYPEPTIDES
#27SITES FOR PLASTID TRANSFORMATION
#28Endothelium-specific nucleic acid regulatory elements and methods and use thereof
#29Genomic engineering of pluripotent cells
#30Use of adenovirus and nucleic acids coding therefor
#31Riboswitch modulated gene therapy for retinal diseases
#32Orthogonal Cas9 proteins for RNA-guided gene regulation and editing
#33Optimized genetic tool for modifying bacteria
#34REVERSE GENETICS USING NON-ENDOGENOUS POL I PROMOTERS
#35Genomic engineering of pluripotent cells
#36Triple vector for expressing antibody molecules in full therapeutic format
#37Tumor-selective E1a and E1b mutants
#38Immunogenic composition
#39Use of adenovirus and nucleic acids coding therefor
#40T7 alpha viral vector system
#41Cell lines for screening odorant and aroma receptors
#42Methods to protect transplanted tissue from rejection
#43Activation of taste receptor genes in mammalian cells using CRISPR-Cas-9
#44Gene Expression Cassette And Product Thereof
#45Genetically engineered larvae for wound healing
#46Reverse genetics systems
#47Inducible eukaryotic expression system
#48Genomic engineering of pluripotent cells
#49Transgenic animal for visualization of ATP and use thereof
#50Chimeric gene constructs for generation of fluorescent transgenic ornamental fish
#51Protein expression enhancer sequences and use thereof
#52Use of adenovirus and nucleic acids coding therefor
#53Optimized expression cassette for expressing a polypeptide with high yield
#54Virus-based expression vectors and uses thereof
#55Targeted mutations
#56Synthetic genes and genetic constructs
#57Artificial nucleic acid molecules
#58Super-enhancers and methods of use thereof
#59Orthogonal Cas9 proteins for RNA-guided gene regulation and editing
#60Inducible eukaryotic expression system
#61Method for improving efficiency of inducing pluripotent stem cell
#62System and method for electroporating a sample
#63Optimized expression cassette for expressing a polypeptide with high yield
#64Use of adenoviruses and nucleic acids that code for said viruses
#65Vectors and methods for genetic immunization
#66Compositions and methods of use thereof for identifying anti-viral agents
#67Vectors and methods for genetic immunization
#68Expression vector
#69Retroviral vector with mini-promoter cassette
#70Orthogonal Cas9 proteins for RNA-guided gene regulation and editing
#71Nucleic acid Construct
#72System and method for electroporating a sample
#73Super-enhancers and methods of use thereof
#74Gene therapy vectors for adrenoleukodystrophy and adrenomyeloneuropathy
#75Gene therapy vectors for adrenoleukodystrophy and adrenomyeloneuropathy
#76Complementing cell lines
#77Compositions and methods for generating an immune response
#78Methods and compositions relating to restricted expression lentiviral vectors and their applications
#79Inducible eukaryotic expression system
#80Transgenic bird expressing foreign gene using endoplasmic reticulum chaperone promoter
#81Control of gene expression
#82System and method for electroporating a sample
#83Chimeric gene constructs for generation of fluorescent transgenic ornamental fish
#84Synthetic genes and genetic constructs
#85Gene therapy vectors for adrenoleukodystrophy and adrenomyeloneuropathy
#86System for increasing gene expression and vector comprising the system
#87CONTROL OF GENE EXPRESSION
#88Reverse genetics systems
#89Female specific insect expression system
#90Drug comprising as the active ingredient proliferative vector containing survivin promoter
#91ENHANCER FOR PROMOTER, AND USE THEREOF
#92Reverse genetics using non-endogenous pol I promoters
#93Methods and materials for increasing expression of recombinant polypeptides
#94Chimeric gene constructs for generation of fluorescent transgenic ornamental fish
#95Synthetic genes and genetic constructs
#96Expression vector for producing protein derived from foreign gene in large quantity using animal cells, and use thereof
#97Promoters for recombinant viral expression
#98CHROMOSOME-BASED PLATFORMS
#99E1-MINUS ADENOVIRUSES AND USE THEREOF
#100Immunogenic compositions for inducing an immune response to HIV
#101Tumor selective E1a and E1b mutants
#102NOVEL USE OF ADENOVIRUSES AND NUCLEIC ACIDS THAT CODE FOR SAID VIRUSES
#103Female specific insect expression system
#104MVA expressing modified HIV envelope, GAG, and POL genes
#105Viral vectors whose replication and, optionally, passenger gene are controlled by a gene switch activated by heat in the presence or absence of a small-molecule regulator
#106Use of AAV replication machinery for improved protein production
#107MVA expressing modified HIV envelope, gag, and pol genes
#108MAMMALIAN CELL EXPRESSION VECTORS AND UTILIZATION
#109VV PROMOTER-DRIVEN OVEREXPRESSION OF RECOMBINANT ANTIGENS
#110Methods and Compositions for Increasing Gene Expression
#111Use of adenovirus and nucleic acids coding therefor
#112DNA fragment and use thereof
#113Compositions and methods for enhanced expression of recombinant polypeptides from a single vector using a peptide cleavage site
#114NOVEL USE OF ADENOVIRUSES AND NUCLEIC ACIDS THAT CODE FOR SAID VIRUSES
#115Nucleic acids for inducing expression of transcripts and proteins and methods for making and using them
#116Vectors and method for genetic immunization
#117Synthetic 5'UTRs, expression vectors, and methods for increasing transgene expression
#118Construct
#119Selectively replicating viral vectors
#120Isolated Polynucleotide Sequence with IRES Activity
#121NUCLEIC ACID CONSTRUCTS
#122USE OF CHICK BETA ACTIN GENE INTRON-1
#123System and method for electroporating a sample
#124VIRUS MEDIATED CYTOPLASMIC EXPRESSION OF DNA VACCINES
#125Synthetic expression vectors for insect cells
#126Adenoviral vector comprising herpes simplex virus type 1 thymidine kinase and a transgene for increasing the expression of the transgene
#127Optimized core promoters and uses thereof
#128Mitochondrial nucleic acid delivery systems
#129Vector for expressing NC protein of HIV and method for producing NC protein using the same
#130Serotype of adenovirus and uses thereof
#131MULTIPLE-COMPARTMENT EUKARYOTIC EXPRESSION SYSTEMS
#132CELL LINES WITH LATENT IMMUNODEFICIENCY VIRUS AND METHODS OF USE THEREOF
#133Use of Caspase-8 Inhibitors for Modulating Hematopoiesis
#134Adenovirus vectors specific for cells expressing androgen receptor and methods of use thereof
#135Expression system incorporating a capsid promoter sequence as an enhancer
#136Crustaceans as production systems for therapeutic proteins
#137E1-MINUS ADENOVIRUSES AND USE THEREOF
#138Antibodies produced in a transgenic avian egg white
#139Artificial chromosomes and transchromosomic avians
#140Herpes simplex virus expressing foreign genes and method for treating cancers therewith
#141Drug comprising as the active ingredient proliferative vector containing survivin promoter
#142Recombinant protein production in a human cell
#143VACCINIA VIRUS HOST RANGE GENES TO INCREASE THE TITER OF AVIPOXVIRUSES
#144Inducible eukaryotic expression system
#145Adenoviral vector-based malaria vaccines
#146HBM variants that modulate bone mass and lipid levels
#147Humanised Baculovirus
#148Pan cancer oncolytic vectors and methods of use thereof
#149TRANSGENIC ROSA26-LUCIFERASE MICE FOR BIOLUMINESCENT IMAGING
#150MVA expressing modified HIV envelope, gag, and pol genes
#151Protein expression systems
#152Stocks of replication-deficient adenovirus
#153Viral vectors whose replication and, optionally, passenger gene are controlled by a gene switch activated by heat in the presence or absence of a small-molecule regulator
#154Replication competent hepatitis C virus and methods of use
#155Host Cells Containing Multiple Integrating Vectors
#156Compositions and methods for enhanced expression of recombinant polypeptides from a single vector using a peptide cleavage site
#157System and method for electroporating a sample
#158Recombinant protein production in a human cell
#159Live virus vaccines
#160Methods
#161Expression systems using mammalian beta-actin promoter
#162Preprotachykinin Enhancer Elements
#163Methods of treating neoplasia with combination target cell-specific adenovirus, chemotherapy and radiation
#164Expression Vectors for Treating Bacterial Infections
#165Means and methods for regulating gene expression
#166Treating immunodeficiencies by intrathymic injection of nucleotide sequences
#167Complementing cell lines
#168Recombinant MVA viruses expressing clade A/G, clade B, and clade C modified HIV env, gag and pol genes
#169Procedure for specific replacement of a copy of a gene present in the recipient genome by the integration of a gene different from that where the integration is made
#170Serotype of adenovirus and uses thereof
#171Nucleic acid constructs
#172Expression vectors with improved safety
#173Methods and Materials for Increasing Expression of Recombinant Polypeptides
#174Means and methods for regulating gene expression
#175Protein isolation
#176Oncolytic adenoviral vectors encoding GM-CSF
#177Lentiviral LTR-deleted vector
#178Sale of fluorescent transgenic ornamental fish
#179Method for the identification of compounds capable of activating latent human immunodeficiency virus (HIV)
#180Isolation, selection and propagation of animal transgenic stem cells
#181New Expression Tools for Multiprotein Applications
#182Methods and materials for increasing expression of recombinant polypeptides
#183Method for Producing Non-Pathogenic Helper Virus-Free Preparations of Herpes Virus Amplicon Vectors, the Helper Virus and the Cells Used in this Method, the Corresponding Generic Tools, as Well as the Applications of These Non-Pathogenic Amplicon Vectors
#184Tumor-Specific Expression of Reporter Genes
#185Use of Caspase-8 Inhibitors for Modulating Hematopoiesis
#186Novel Herpes Simplex Viruses
#187BAK PROMOTER EXPRESSION SYSTEM
#188Over-expression of enzymes involved in post-translational protein modifications in human cells
#189Collapsin response mediator protein-1 (CRMP-1) transcriptional regulatory nucleic acid sequences
#190Promoters for RNA interference
#191Methods and compositions relating to restricted expression lentiviral vectors and their applications
#192Plasmid having three complete transcriptional units and immunogenic compositions for inducing an immune response to hiv
#193Autologous upregulation mechanism allowing optimized cell type-specific and regulated gene expression cells
#194Methods for producing minus-strand RNA viral vectors using hybrid promoter comprising cytomegalovirus enhancer and chicken β-actin promoter
#195Growth differentiation factor promoter and uses therefor
#196HUMAN DISEASE MODELING USING SOMATIC GENE TRANSFER
#197Sequences upstream of the carp gene, vectors containing them and uses thereof
#198Adenovirus packaging cell lines
#199Reversibly immortalised olfactory ensheathing glia and their use to promote neuronal regeneration
#200Methods and compositions for lowering the level of tumor necrosis factor (TNF) in TNF-associated disorders
#201Novel use of adenoviruses and nucleic acids that code for said viruses
#202Truncated CMV promoters and vectors containing same
#203Isolated polynucleotide sequence with IRES activity
#204Methods of obtaining neural stem cells
#205Method for creating myeloid cell lines
#206Recombinant protein production in a human cell
#207Method of making a genetically modified mammalian cell
#208HYBRID VECTOR HAVING A CYTOMEGALOVIRUS ENHANCER AND MYELOPROLIFERATIVE SARCOMA VIRUS PROMOTER
#209Serotype of adenovirus and uses thereof
#210Vectors for expressing exogenous gene or exogenous nucleic acid sequences
#211Methods and compositions for in vivo inflammation monitoring
#212Methods for modulating apoptotic cell death
#213Addition of transgenes into adenoviral vectors
#214Vectors
#215Cell lines for production of replication-defective adenovirus
#216RNA polymerase III promoter, process for producing the same and method of using the same
#217Ocular gene therapy
#218Chromosome-based platforms
#219Nucleotide sequences of shrimp beta-actin and actin promoters and their use in gentic transformation technology
#220Adiponectin gene therapy
#221Human prolyl isomerase 1 (PIN 1) promoter and uses thereof
#222Lentiviral vectors carrying synthetic bi-directional promoters and uses thereof
#223Viral agents
#224Glycosylated interferon α
#225Avians that produce eggs containing exogenous proteins
#226Production of exogenous proteins in egg whites of transgenic chickens
#227Multiple-compartment eukaryotic expression systems
#228Lentiviral LTR-deleted vector
#229Artificial chromosomes and transchromosomic avians
#230Gene trap system
#231Glycosylated interferon alpha obtained from a transgenic chicken
#232Nucleic acid sequences encoding proteins capable of associating into a virus-like particle
#233Method of screening antiobesity agents and animal model of obesity
#234Recombinant poxvirus comprising at least two compox ATI promoters
#235High yield heterologous expression cell lines for expression of gene products with human glycosylation pattern
#236Method of expressing gene in transgenic birds using retrovirus vector and transgenic birds thus obtained
#237Methods for constructing antibiotic resistance free vaccines
#238Transgenic animals for producing specific isotypes of human antibodies via non-cognate switch regions
#239MVA expressing modified HIV envelope, gag, and pol genes
#240Method of producing an exogenous protein in the egg of a chicken
#241Methods and vectors for controlling gene expression
#242Episomal expression system
#243Sequences upstream of the CARP gene, vectors containing them and uses thereof
#244Inducible eukaryotic expression system
#245Recombinant expression of factor VIII in human cells
#246Novel use of adenoviruses and nucleic acids coding therefor
#247Expression system for stem-loop rna molecule having rnai effect
#248Transgenic chickens producing exogenous protein in eggs
#249Methods for identifying a cell or an embryo carrying a Y chromosome
#250Nuclear factors associated with transcriptional regulation
#251SYSTEM FOR PRODUCING SYNTHETIC PROMOTERS
#252Isolated avian cell that expresses Vaccinia virus host range genes
#253Methods of treating neoplasia with combinations of target cell-specific adenovirus and chemotherapy
#254Genetic immunization of transgenic animals with non-eukaryotic expression systems
#255Adenovirus packaging cell lines
#256Chromosome-based platforms
#257Target cell-specific adenoviral vectors containing E3 and methods of use thereof
#258Transcriptionally-activated AAV inverted terminal repeats (ITRs) for use with recombinant AAV vectors
#259Expression vectors for treating bacterial infections
#260Control of gene expression
#261Stable bactericidal/permeability-increasing protein products and pharmaceutical compositions containing the same
#262Oncolytic adenoviral vectors encoding GM-CSF
#263Expression vector encoding coronavirus-like particle
#264Complementing cell lines
#265System and method for electroporating a sample
#266Novel clock gene promoter
#267Control of gene expression
#268Promoter sequences
#269Lentiviral LTR-deleted vector
#270Serotype of adenovirus and uses thereof
#271Recombinant fibroblast growth factor analogs
#272Control of gene expression in eukaryotic cells
#273System for producing synthetic promoters
#274Means and methods for nucleic acid delivery vehicle design and nucleic acid transfer
#275Recombinant negative strand virus RNA expression systems and vaccines
#276Pan cancer oncolytic vectors and methods of use thereof
#277Means and methods for regulating gene expression
#278Compositions and methods for determining anti-viral drug susceptibility and resistance and anti-viral drug screening
#279Method and cell composition for screening compounds for anti-inflammatory activity
#280Poxvirus with targeted infection specificity
#281Isolation, selection and propagation of animal transgenic stem cells
#282Methods for detecting metalloproteinase inhibitors
#283Oncolytic adenoviral vectors encoding GM-CSF
#284Collapsin response mediator protein-1 (CRMP-1) transcriptional regulatory nucleic acid sequences
#285Chromosome-based platforms
#286Anti-neoplastic viral agents
#287Recombinant protein production in permanent amniocytic cells that comprise nucleic acid encoding adenovirus E1A and E1B proteins
#288Overexpression of enzymes involved in post-translational protein modifications in human cells
#289Cell-specific and/or tumor-specific promoter retargeting of herpes γ 34.5 gene expression
#290Expression vector
#291Replication competent hepatitis C virus and methods of use
#292Method of genetic screening using an amplifiable gene
#293Viral vectors whose replication and, optionally, passenger gene are controlled by a gene switch activated by heat in the presence or absence of a small molecule regulator
#294DNA construct for effecting homologous recombination and uses thereof
#295Hepatocellular carcinoma specific promoter and uses thereof
#296Method for targeting transcriptionally active loci
#297Method for identifying target epitopes of the T cell mediated immune response and for assaying epitope-specific T cells
#298Efficient production of IgA in recombinant mammalian cells
#299Host cells containing multiple integrating vectors
#300Chicken anemia virus mutants and vaccines and uses based on the viral proteins VP1, VP2 and VP3 or sequences of that virus coding therefor