112314 ⎘
Vector systems having a special element relevant for transcription from vertebrates mammalian
EXPRESSION AND SECRETION SYSTEM
#2BIDIRECTIONAL CHEF1 VECTORS
#3METHODS OF REDOSING GENE THERAPY VECTORS
#4CARDIOMYOCYTE-DERIVED NUCLEIC ACID REGULATORY ELEMENTS AND METHODS AND USE THEREOF
#5EXPRESSION AND SECRETION SYSTEM
#6Liver-Specific Nucleic Acid Regulatory Elements and Methods and Use Thereof
#7Promoter of Hspa5 Gene
#8Methods and compositions for reducing the immunogenicity of chimeric notch receptors
#9METHODS AND COMPOSITIONS FOR REDUCING THE IMMUNOGENICITY OF CHIMERIC NOTCH RECEPTORS
#10SYNP88, A PROMOTER FOR THE EXPRESSION OF GENES
#11Modulation of Engineered Immune Cell Receptor Translation Using Noncoding Sequence Elements
#12Method of detecting and/or identifying adeno-associated virus (AAV) sequences and isolating novel sequences identified thereby
#13REGULATABLE ADENO-ASSOCIATED VIRUS (AAV) VECTOR
#14TRANSCRIPTIONAL REGULATORY ELEMENT AND ITS USE IN ENHANCING THE EXPRESSION OF HETEROLOGOUS PROTEIN
#15DLX2 VECTOR
#16Method of detecting and/or identifying adeno-associated virus (AAV) sequences and isolating novel sequences identified thereby
#17Adeno-associated virus (AAV) clades, sequences, vectors containing same, and uses therefor
#18Adeno-associated virus (AAV) serotype 8 sequences, vectors containing same, and uses therefor
#19Adeno-associated virus (AAV) clades, sequences, vectors containing same, and uses therefor
#20AAV VIRIONS WITH DECREASED IMMUNOREACTIVITY AND USES THEREFOR
#21NUCLEIC ACID CONSTRUCTS AND GENE THERAPY VECTORS FOR USE IN THE TREATMENT OF WILSON DISEASE
#22Muscle-Specific Nucleic Acid Regulatory Elements and Methods and Use Thereof
#23Optimized Liver-Specific Expression Systems for FVIII and FIX
#24ADENO-ASSOCIATED VIRUS (AAV) CLADES, SEQUENCES, VECTORS CONTAINING SAME, AND USES THEREFOR
#25METHOD OF DETECTING AND/OR IDENTIFYING ADENO-ASSOCIATED VIRUS (AAV) SEQUENCES AND ISOLATING NOVEL SEQUENCES IDENTIFIED THEREBY
#26Transcriptional regulatory element and its use in enhancing the expression of heterologous protein
#27ADENO-ASSOCIATED VIRUS (AAV) CLADES, SEQUENCES, VECTORS CONTAINING SAME, AND USES THEREFOR
#28BIDIRECTIONAL CHEF1 VECTORS
#29Muscle-specific nucleic acid regulatory elements and methods and use thereof
#30EXPRESSION AND SECRETION SYSTEM
#31CANCER IMAGING WITH THERAPY: THERANOSTICS
#32METHODS OF REDOSING GENE THERAPY VECTORS
#33SYNP88, a promoter for the specific expression of genes in retinal ganglion cells
#34Adeno-associated viral (AAV) vectors useful for transducing adipose tissue
#35Compositions and methods for the expression of CRISPR guide RNAs using the H1 promoter
#36ADENO-ASSOCIATED VIRUS (AAV) CLADES, SEQUENCES, VECTORS CONTAINING SAME, AND USES THEREFOR
#37Method of detecting and/or identifying adeno-associated virus (AAV) sequences and isolating novel sequences identified thereby
#38Method of detecting and/or identifying adeno-associated virus (AAV) sequences and isolating novel sequences identified thereby
#39Method of detecting and/or identifying adeno-associated virus (AAV) sequences and isolating novel sequences identified thereby
#40Vector for targeting the human Rosa26 gene
#41Engineered Cellular Pathways for Programmed Autoregulation of Differentiation
#42Liver-specific nucleic acid regulatory elements and methods and use thereof
#43Methods of rapid ligation-independent cloning of DNA and uses thereof
#44METHODS OF USE OF INHIBITORS OF PHOSPHODIESTERASES AND MODULATORS OF NITRIC OXIDE, REACTIVE OXYGEN SPECIES, AND METALLOPROTEINASES IN THE TREATMENT OF PEYRONIE'S DISEASE, ARTERIOSCLEROSIS AND OTHER FIBROTIC DISEASES
#45Compositions and methods for the expression of CRISPR guide RNAS using the H1 promoter
#46AAV virions with decreased immunoreactivity and uses therefor
#47Adeno-associated virus (AAV) serotype 8 sequences, vectors containing same, and uses therefor
#48PDL1 block CAR-T transgenic vector for suppressing immune escape, preparation method thereof, and application of the same
#49REVERSE GENETICS USING NON-ENDOGENOUS POL I PROMOTERS
#50Promoter for cell-specific gene expression and uses thereof
#51Promoter of Hspa5 gene
#52Methods for cardiomyocyte survival, proliferation or differentiation by NRG-2
#53Promoter
#54Adeno-associated virus (AAV) clades, sequences, vectors containing same, and uses therefor
#55Liver-specific nucleic acid regulatory elements and methods and use thereof
#56Method of detecting and/or identifying adeno-associated virus (AAV) sequences and isolating novel sequences identified thereby
#57Adeno-associated virus (AAV) clades, sequences, vectors containing same, and uses therefor
#58Adeno-associated virus (AAV) serotype 8 sequences, vectors containing same, and uses therefor
#59Adeno-associated virus (AAV) clades, sequences, vectors containing same, and uses therefor
#60Compositions and methods for the expression of CRISPR guide RNAs using the H1 promoter
#61Methods and compositions for reducing the immunogenicity of chimeric notch receptors
#62Vectors Conditionally Expressing Protein
#63METHODS OF USE OF INHIBITORS OF PHOSPHODIESTERASES AND MODULATORS OF NITRIC OXIDE, REACTIVE OXYGEN SPECIES, AND METALLOPROTEINASES IN THE TREATMENT OF PEYRONIE'S DISEASE, ARTERIOSCLEROSIS AND OTHER FIBROTIC DISEASES
#64AAV VIRIONS WITH DECREASED IMMUNOREACTIVITY AND USES THEREFOR
#65Method for expression of small RNA molecules within a cell
#66Compositions and methods for the expression of CRISPR guide RNAs using the H1 promoter
#67RETROVIRAL VECTORS CONTAINING A REVERSE ORIENTATION HUMAN UBIQUITIN C PROMOTER
#68ADENOVIRAL TUMOR DIAGNOSTICS
#69RAAV-GUANYLATE CYCLASE COMPOSITIONS AND METHODS FOR TREATING LEBER'S CONGENITAL AMAUROSIS-1 (LCA1)
#70Optimized liver-specific expression systems for FVIII and FIX
#71rAAV vector compositions, methods for targeting vascular endothelial cells and use in treatment of type I diabetes
#72Method of detecting and/or identifying adeno-associated virus (AAV) sequences and isolating novel sequences identified thereby
#73METHOD AND COMPOSITION TO INCREASE RADIATION-INDUCED TUMOR THERAPEUTIC EFFECTS
#74Synthetic promoters for high throughput screening and gene modulation
#75Expression and secretion system
#76Nucleic acid constructs and gene therapy vectors for use in the treatment of Wilson's disease and other conditions
#77Nucleic acid constructs and gene therapy vectors for use in the treatment of Wilson disease
#78Adeno-associated virus (AAV) serotype 8 sequences, vectors containing same, and uses therefor
#79Method of detecting and/or identifying adeno-associated virus (AAV) sequences and isolating novel sequences identified thereby
#80STEM CELL GENE TARGETING
#81Muscle-specific nucleic acid regulatory elements and methods and use thereof
#82Promoter and regulatory elements for improved expression of heterologous genes in host cells
#83REGULATION OF ENDOGENOUS GENE EXPRESSION IN CELLS USING ZINC FINGER PROTEINS
#84Method of detecting and/or identifying adeno-associated virus (AAV) sequences and isolating novel sequences identified thereby
#85LIGAND SCREENING AND DISCOVERY
#86Liver-specific nucleic acid regulatory elements and methods and use thereof
#87Adeno-associated virus (AAV) clades, sequences, vectors containing same, and uses therefor
#88Adeno-associated virus (AAV) serotype 8 sequences, vectors containing same, and uses therefor
#89ADENOVIRAL TARGETING, COMPOSITIONS AND METHODS THEREFOR
#90Adeno-associated virus (AAV) clades, sequences, vectors containing same, and uses therefor
#91METHOD AND COMPOSITION TO INCREASE RADIATION-INDUCED TUMOR THERAPEUTIC EFFECTS
#92Artificial introns
#93Muscle-specific nucleic acid regulatory elements and methods and use thereof
#94Adeno-associated viral (AAV) vectors useful for transducing adipose tissue
#95Super-enhancers and methods of use thereof
#96RECOMBINANT VECTOR WITH STABILIZING A-LOOP
#97Adeno-associated virus (AAV) serotype 8 sequences, vectors containing same, and uses therefor
#98mda-9/syntenin promoter to image and treat metastatic cancer cells
#99Method of detecting and/or identifying adeno-associated virus (AAV) sequences and isolating novel sequences identified thereby
#100Compositions and methods for the expression of CRISPR guide RNAs using the H1 promoter
#101Placental like alkaline phosphatase (PLAP) promoter mediated cell targeting
#102S100B mini-promoters
#103Regulatory nucleic acid elements
#104Adeno-associated virus (AAV) glades, sequences, vectors containing same, and uses therefor
#105Adeno-associated virus (AAV) serotype 8 sequences, vectors containing same, and uses therefor
#106Method for expression of small RNA molecules within a cell
#107Adeno-associated virus (AAV) serotype 8 sequences, vectors containing same, and uses therefor
#108Transcription units and the use thereof in expression vectors
#109Artificial nucleic acid molecules comprising a 5′TOP UTR
#110Baculovirus-based vaccines
#111Methods of inducing regulated pancreatic hormone production in non-pancreatic islet tissues
#112Adenoviral tumor diagnostics
#113Method of treating or retarding the development of blindness
#114Lentiviral vectors containing an MHC class I, MHC class II, or B2 microglobulin upstream promoter sequence
#115Promoter derived from human gene
#116Methods and compositions relating to restricted expression lentiviral vectors and their applications
#117Vectors conditionally expressing protein
#118Chimeric promoter for cone photoreceptor targeted gene therapy
#119Genetic element that enhances protein translation
#120Artificial introns
#121Engineered cellular pathways for programmed autoregulation of differentiation
#122PCP2 mini-promoters
#123Expression vector for animal cells including CSP-B 5′-SAR factor and method for producing recombinant proteins using same
#124Expression system with SAR element from IFNα2
#125Expression and secretion system
#126Pol I promoter derived from Vero cells and recombinant vector containing same
#127Methods for use of a specific anti-angiogenic adenoviral agent
#128Adeno-associated virus (AAV) serotype 8 sequences, vectors containing same, and uses therefor
#129Hybrid promoter and recombinant vector comprising the same
#130Gene delivery system having enhanced tumor-specific expression, and recombinant gene expression regulating sequence
#131MIR-21 promoter driven targeted cancer therapy
#132Promoters exhibiting endothelial cell specificity and methods of using same
#133Nucleic acids encoding FOXD3 promoter and methods to isolate FOXD3 expressing cells
#134Polynucleotide constructs, pharmaceutical compositions and methods for targeted downregulations of angiogenesis and anticancer therapy
#135rAAV-guanylate cyclase compositions and methods for treating lebers congenital amaurosis-1 (LCA1)
#136Methods and compositions for gene therapy and GHRH therapy
#137Baculovirus-mediated transgene expression in both mammalian and insect cells
#138Method of detecting and/or identifying adeno-associated virus (AAV) sequences and isolating novel sequences identified thereby
#139Promoters exhibiting endothelial cell specificity and methods of using same for regulation of angiogenesis
#140Regulation of endogenous gene expression in cells using zinc finger proteins
#141DNA regulatory element for the expression of transgenes in neurons of a subject and uses thereof
#142Constructs for enhancement of gene expression in muscle
#143DNA CONSTRUCT, AND PROCESS FOR PRODUCTION OF RECOMBINANT CHO CELL USING SAME
#144Isolation, Cloning, Sequencing and Functional analysis of ss-casein promoter along with the regions of exon1, intron1 and exon2 using mammary gland derived cell line of Buffalo (Bubulus bubalis)
#145Transgenic non-human animal and uses thereof
#146Method and Composition to Increase Radiation-Induced Tumor Therapeutic Effects
#147Cardiac-specific nucleic acid regulatory elements and methods and use thereof
#148METHOD OF TREATING OR RETARDING THE DEVELOPMENT OF BLINDNESS
#149METHODS FOR PROTECTING DOPAMINERGIC NEURONS FROM STRESS AND PROMOTING PROLIFERATION AND DIFFERENTIATION OF OLIGODENDROCYTE PROGENITORS BY NRG-2
#150DUAL VECTOR FOR INHIBITION OF HUMAN IMMUNODEFICIENCY VIRUS
#151Promoters exhibiting endothelial cell specificity and methods of using same
#152Reverse genetics using non-endogenous pol I promoters
#153Stem cell beacon
#154Methods of Use of Inhibitors of Phosphodiesterases and Modulators of Nitric Oxide, Reactive Oxygen Species, and Metalloproteinases in the Treatment of Peyronie's Disease, Arteriosclerosis and Other Fibrotic Diseases
#155Methods for modulating embryonic stem cell differentiation
#156Polynucleotides encoding a human TRIM-Cyp fusion polypeptide, compositions thereof, and methods of using same
#157TRUNCATED ACTIVIN TYPE II RECEPTOR AND METHODS OF USE
#158MIR-21 promoter driven targeted cancer therapy
#159CHROMOSOME-BASED PLATFORMS
#160NON-AD5 ADENOVIRAL VECTORS AND METHODS AND USES RELATED THERETO
#161Gene delivery system and method of use
#162Use of VEGF and homologues to treat neuron disorders
#163Expression of factor IX in gene therapy vectors
#164Adeno-associated virus (AAV) sequences and isolating novel sequences identified thereby
#165Polynucleotide constructs, pharmaceutical compositions and methods for targeted downregulation of angiogenesis and anticancer therapy
#166DNA transfection system for the generation of negative strand RNA virus
#167Regulation of endogenous gene expression in cells using zinc finger proteins
#168ADENO-ASSOCIATED VIRUS (AAV) CLADES, SEQUENCES, VECTORS CONTAINING SAME, AND USES THEREFOR
#169Muscle-specific expression vectors
#170PROMOTERS EXHIBITING ENDOTHELIAL CELL SPECIFICITY AND METHODS OF USING SAME FOR REGULATION OF ANGIOGENESIS
#171PROMOTERS EXHIBITING ENDOTHELIAL CELL SPECIFICITY AND METHODS OF USING SAME
#172Protein Expression
#173Liver-specific nucleic acid regulatory elements and methods and use thereof
#174Bovine immunodeficiency virus (BIV) based vectors
#175Method for detecting adeno-associated virus
#176Viral vectors whose replication and, optionally, passenger gene are controlled by a gene switch activated by heat in the presence or absence of a small-molecule regulator
#177Promoters exhibiting endothelial cell specificity and methods of using same for regulation of angiogenesis
#178Recombinant gene which enhances the ability of fish to tolerate low dissolved oxygen stress and the use thereof
#179MUTANT MUSCLE-SPECIFIC ENHANCERS
#180Methods of reducing excitotoxicity-induced retinal ganglionic neuron degeneration by an orthodenticle HOMOLOG2 (OTX2) homeoprotein
#181Method for expression of small RNA molecules within a cell
#182TRANSGENIC RABBITS PRODUCING HUMAN FACTOR VII
#183Methods and Compositions for Increasing Gene Expression
#184Composition and Methods for Expressing Reporter Molecules in Mammalian Cells
#185Truncated activin type II receptor and methods of use
#186Use of regulatory sequences for specific, transient expression in neuronal determined cells
#187Use of regulatory sequences for specific, transient expression in neuronal determined cells
#188Compositions and methods for enhanced expression of recombinant polypeptides from a single vector using a peptide cleavage site
#189Regulatory nucleic acid elements
#190Nucleic acids encoding SOX10 promoter and methods to isolate SOX10 expressing cells
#191Engineered cellular pathways for programmed autoregulation of differentiation
#192Baculovirus-Based Vaccines
#193Alteration of tumor growth using zinc finger proteins
#194Method of treating or retarding the development of blindness
#195Regulation of endogenous gene expression in cells using zinc finger proteins
#196DNA regulatory element for the expression of transgenes in neurons of a subject and uses thereof
#197MAMMARY GLAND- SPECIFIC HUMAN ERYTHEROPOIETIN EXPRESSION VECTOR, TRANSGENIC ANIMAL AND METHOD FOR PRODUCING HUMAN ERYTHROPOIETIN USING SAME
#198Long-term in vivo transgene expression
#199Compositions and methods for retinal transduction and photoreceptor specific transgene expression
#200CELL CAPABLE OF EXPRESSING LACRITIN AT HIGH LEVEL
#201Use of Pol III promoters for controlled expression of therapeutic proteins
#202TARGETED TUMOR THERAPY BY USE OF RECOMBINANT ADENOVIRUS VECTORS THAT SELECTIVELY REPLICATE IN HYPOXIC REGIONS OF TUMORS
#203In Vivo Production and Delivery of Erythropoietin or Insulinotropin for Gene Therapy
#204Genetically modified animal for use in evaluating harmfulness of test substance
#205Methods for expression of transgenes
#206ISOLATED DNA FRAGMENT OF THE HUMAN A33 PROMOTER AND ITS USE TO CONTROL THE EXPRESSION OF A HETEROLOGOUS GENE IN TUMOR CELLS
#207Polynucleotide
#208Mitochondrial nucleic acid delivery systems
#209METHODS FOR MODULATING EMBRYONIC STEM CELL DIFFERENTIATION
#210Olig1 mini-promoters
#211Promoters exhibiting endothelial cell specificity and methods of using same for regulation of angiogenesis
#212Transgenic non-human animals expressing a truncated activin type II receptor
#213Use of VEGF and homologues to treat neuron disorders
#214METHOD FOR THE PRODUCTION OF FUSION PROTEINS IN TRANSGENIC MAMMAL MILK
#215Targeting the Rosa26 gene in human embryonic stem cells
#216AGENTS FOR TREATING MALIGNANT MESOTHELIOMA
#217Promoters exhibiting endothelial cell specificity and methods of using same
#218MULTIPLE-COMPARTMENT EUKARYOTIC EXPRESSION SYSTEMS
#219Use of Caspase-8 Inhibitors for Modulating Hematopoiesis
#220REGULATORY ELEMENTS THAT MEDIATE RETINAL CELL-SPECIFIC GENE EXPRESSION
#221Adeno-associated virus (AAV) serotype 8 sequences, vectors containing same, and uses therefor
#222Truncated Activin Type II Receptor and Methods of Use
#223Herpes simplex virus expressing foreign genes and method for treating cancers therewith
#224Use of regulatory sequences for specific, transient expression in neuronal determined cells
#225Metastatic colon cancer specific promoter and uses thereof
#226ENRICHED PREPARATION OF HUMAN FETAL MULTIPOTENTIAL NEURAL STEM CELLS
#227Model animal of schizophrenia
#228Epididymal lipocalin gene and uses thereof
#229Transgenic animal model for alzheimer's disease
#230RAAV VECTOR-BASED COMPOSITIONS AND METHODS FOR THE PREVENTION AND TREATMENT OF MAMMALIAN DISEASES
#231Non-invasive, in vivo fluorescent imaging of the nervous system in whole living animal
#232Ligand screening and discovery
#233Pan cancer oncolytic vectors and methods of use thereof
#234Bovine immunodeficiency virus (BIV) based vectors
#235RECOMBINANT ADENOVIRAL VECTORS AND METHODS OF USE
#236TRANSGENIC ROSA26-LUCIFERASE MICE FOR BIOLUMINESCENT IMAGING
#237Adenoviral vectors having a protein IX deletion
#238Method of Treating or Retarding the Development of Blindness
#239Viral vectors whose replication and, optionally, passenger gene are controlled by a gene switch activated by heat in the presence or absence of a small-molecule regulator
#240Dengue Reporter Virus and Methods of Making and Using the Same
#241DNA-transfection system for the generation of infectious influenza virus
#242DNA-transfection system for the generation of infectious influenza virus
#243Polynucleotide constructs, pharmaceutical compositions and methods for targeted downregulation of angiogenesis and anticancer therapy
#244Adenoviral vectors having a protein IX deletion
#245AAV vectors for gene delivery to the lung
#246Host Cells Containing Multiple Integrating Vectors
#247Compositions and methods for enhanced expression of recombinant polypeptides from a single vector using a peptide cleavage site
#248ALK protein tyrosine kinase, cells and methods embodying and using same
#249Methods
#250Expression systems using mammalian beta-actin promoter
#251Methods of treating neoplasia with combination target cell-specific adenovirus, chemotherapy and radiation
#252DNA-transfection system for the generation of infectious influenza virus
#253Transgenic mammal carrying GANP gene transferred thereinto and utilization thereof
#254Vectors having both isoforms of beta-hexosaminidase and uses of the same
#255Vectors for tissue-specific replication
#256Cancer-targeted viral vectors
#257Means and methods for regulating gene expression
#258Expression Vectors and Methods for Obtaining Nk Cell Specific Expression
#259Adenoviral vectors having a protein IX deletion
#260Procedure for specific replacement of a copy of a gene present in the recipient genome by the integration of a gene different from that where the integration is made
#261ADENOVIRAL VECTORS HAVING A PROTEIN IX DELETION
#262Transgenic animal
#263Expression of factor IX in gene therapy vectors
#264Method for producing transgenic rats
#265Target Cell-Specific Short Interfering Rna and Methods of Use Thereof
#266Means and methods for regulating gene expression
#267Regulatory Nucleic Acid Elements
#268Oncolytic adenoviral vectors encoding GM-CSF
#269Methods And Compositions For Combinatorial Approaches To Cancer Gene Therapy
#270Vectors for tissue-specific replication
#271Methods and Compositions for Cytokine Expression and Treatment of Tumors
#272Vectors for tissue-specific replication
#273Adeno-associated virus (AAV) serotype 8 sequences, vectors containing same, and uses therefor
#274Adeno-associated virus (AAV) serotype 8 sequences, vectors containing the same, and uses therefor
#275REGULATORY ELEMENTS FOR DELIVERY TO THE LIVER
#276Use of VEGF and homologuest to treat neuron disorders
#277Isolation, selection and propagation of animal transgenic stem cells
#278AAV virions with decreased immunoreactivity and uses therefor
#279Method for expression of small antiviral RNA molecules within a cell
#280COMPOSITION AND METHODS FOR EXPRESSING REPORTER MOLECULES IN MAMMALIAN CELLS
#281Means and methods for producing a stabilized cell of interest
#282Methods And Compositions Involving S-Ship Promoter Regions
#283Treatment of diabetes with synthetic beta cells
#284Use of Caspase-8 Inhibitors for Modulating Hematopoiesis
#285Adenoviral vectors having a protein IX deletion
#286RECOMBINANT ADENOVIRAL VECTORS AND METHODS OF USE
#287Use of VEGF and homologues to treat neuron disorders
#288Minigene expression cassette
#289Novel Herpes Simplex Viruses
#290Stem Cell Beacon
#291Bovine immunodeficiency virus (BIV) based vectors
#292Selective Killing Of Cancer Cells By Induction Of Acetyltransferase Via Tnf-Alpha And Il-6
#293Methods and compositions relating to restricted expression lentiviral vectors and their applications
#294Adept or gdept producing acetaldehyde
#295Self-rearranging DNA vectors
#296Growth differentiation factor promoter and uses therefor
#297Sequences upstream of the carp gene, vectors containing them and uses thereof
#298Cancer gene therapeutic drug
#299Method for selective expression of therapeutic genes by hyperthermia
#300Cancer gene therapeutic drug