112324 ⎘
Vectors comprising a special translation-regulating system translation of more than one cistron
Sub-classes:STOICHIOMETRIC GAS VESICLE EXPRESSION SYSTEM AND RELATED CONSTRUCTS, GENETIC CIRCUITS, VECTORS, CELLS, HOSTS, COMPOSITIONS, METHODS AND SYSTEMS
#2ARMED CHIMERIC RECEPTORS AND METHODS OF USE THEREOF
#3Polycistronic Expression of Gut Peptides
#4MULTIPLEX ASSAY
#5STEM CELL DERIVED LINEAGE BARCODING
#6A NON-HUMAN MAMMAL COMPRISING IN ITS GENOME AT LEAST TWO HUMAN LEUKOCYTE ANTIGEN (HLA) CLASS I ALLELES, METHODS OF MAKING SUCH MAMMAL AND USES THEREOF
#7ANTI-FIBROUS CELLS, MEDICAMENT COMPRISING THE CELLS, AND METHOD FOR OBTAINING THESE CELLS
#8NFAT-RESPONSIVE REPORTER SYSTEMS FOR ASSESSING CHIMERIC ANTIGEN RECEPTOR ACTIVATION AND METHODS OF MAKING AND USING THE SAME
#9DNA MOLECULES PRODUCING CUSTOM DESIGNED REPLICATING AND NON-REPLICATING NEGATIVE STRANDED RNA VIRUSES AND USES THERE OF
#10DNA MOLECULES PRODUCING CUSTOM DESIGNED REPLICATING AND NON-REPLICATING NEGATIVE STRANDED RNA VIRUSES AND USES THERE OF
#11Methods and compositions for rapid generation of single and multiplexed reporters in cells
#12COMPOSITION AND METHODS FOR IMPROVING HEART FUNCTION AND TREATING HEART FAILURE
#13Production System
#14CHIMERIC GENE CONSTRUCTS FOR GENERATION OF FLUORESCENT TRANSGENIC ORNAMENTAL FISH
#15AFFINITY MATURATED T CELL RECEPTORS AND USE THEREOF
#16NON-DISRUPTIVE GENE TARGETING
#17Transposon-based transfection system for primary cells
#18MULTICISTRONIC VECTOR FOR SURFACE ENGINEERING LENTIVIRAL PARTICLES
#19MULTIPLE VECTOR SYSTEM AND USES THEREOF
#20STEM CELL DERIVED LINEAGE BARCODING
#21Genome editing without nucleases
#22GENETICALLY-MODIFIED T CELLS COMPRISING A MODIFIED INTRON IN THE T CELL RECEPTOR ALPHA GENE
#23MULTIPLEX ASSAY
#24NON-DISRUPTIVE GENE TARGETING
#25Minimal volume reprogramming of mononuclear cells
#26RNA-GUIDED GENE EDITING AND GENE REGULATION
#27Genome Editing without Nucleases
#28Methods for directed differentiation of pluripotent stem cells to immune cells
#29RNA-GUIDED GENE EDITING AND GENE REGULATION
#30Methods and compositions for rapid generation of single and multiplexed reporters in cells
#31Expression systems
#32Expression Constructs and Methods for Expressing Polypeptides in Eukaryotic Cells
#33Genetically-modified T cells comprising a modified intron in the T cell receptor alpha gene
#34Enhanced production of recombinant proteins by transient transfection of suspension-growing mammalian cells
#35CMV vaccines
#36Nonviral minicircle vector carrying SOX gene and construction method therefor
#37DNA molecules producing custom designed replicating and non-replicating negative stranded RNA viruses and uses there of
#38Multi-chain eukaryotic display vectors and uses thereof
#39Transposon-based transfection system for primary cells
#40Affinity maturated T cell receptors and use thereof
#41Hybrid dual recombinant AAV vector systems for gene therapy
#42Vectors for expression of prostate-associated antigens
#43Minimal volume reprogramming of mononuclear cells
#44RNA-guided gene editing and gene regulation
#45Methods for directed differentiation of pluripotent stem cells to immune cells
#46Recombinant vectors comprising 2A peptide
#47Multi-Transgenic Pig for Xenotransplantation
#48Method for expression of small RNA molecules within a cell
#49Inducible eukaryotic expression system
#50Chimeric gene constructs for generation of fluorescent transgenic ornamental fish
#51Methods and compositions for rapid generation of single and multiplexed reporters in cells
#52Methods and compositions relating to improved lentiviral vectors and their applications
#53Multi-chain eukaryotic display vectors and uses thereof
#54Protein production method
#55Composition and method for imaging stem cells
#56Expression Constructs and Methods for Expressing Polypeptides in Eukaryotic Cells
#57Multi-lineage hematopoietic precursor cell production by genetic programming
#58Genome editing without nucleases
#59Evolution of high-titer virus-like vesicles for vaccine applications
#60Synthetic genes and genetic constructs
#61Methods and compositions relating to improved lentiviral vectors and their applications
#62Expression in insect cells of genes with overlapping open reading frames, methods and compositions therefor
#63CMV vaccines
#64Vectors for expression of prostate-associated antigens
#65Inducible eukaryotic expression system
#66Chimeric antigen receptors targeting GPC3 and uses thereof
#67RNA-guided gene editing and gene regulation
#68Effective delivery of large genes by dual AAV vectors
#69Methods and compositions relating to improved lentiviral vectors and their applications
#70Multi-chain eukaryotic display vectors and uses thereof
#71Constructs containing multiple expression cassettes for cancer therapy
#72Minimal volume reprogramming of mononuclear cells
#73Translational enhancer-element dependent vector systems
#74Methods and compositions for synthesis of nucleic acid molecules using multiple recognition sites
#75Protein production method
#76Method for expression of small RNA molecules within a cell
#77EXPRESSION CONSTRUCTS AND METHODS FOR EXPRESSING POLYPEPTIDES IN EUKARYOTIC CELLS
#78Expression in insect cells of genes with overlapping open reading frames, methods and compositions therefor
#79Alphavirus vectors for respiratory pathogen vaccines
#80Complementing cell lines
#81Methods and compositions relating to restricted expression lentiviral vectors and their applications
#82Inducible eukaryotic expression system
#83Methods of treating HIV diseases using novel expression vectors
#84Methods and compositions relating to improved lentiviral vectors and their applications
#85Control of gene expression
#86Multi plasmid system for the production of influenza virus
#87Chimeric gene constructs for generation of fluorescent transgenic ornamental fish
#88Multi-chain eukaryotic display vectors and uses thereof
#89Methods and compositions for synthesis of nucleic acid molecules using multiplerecognition sites
#90Synthetic genes and genetic constructs
#91Polynucleotide constructs, pharmaceutical compositions and methods for targeted downregulations of angiogenesis and anticancer therapy
#92Multi plasmid system for the production of influenza virus
#93Methods and compositions relating to improved lentiviral vectors and their applications
#94Promoters exhibiting endothelial cell specificity and methods of using same for regulation of angiogenesis
#95METHODS AND COMPOSITIONS FOR SYNTHESIS OF NUCLEIC ACID MOLECULES USING MULTIPLERECOGNITION SITES
#96USE OF MEGANUCLEASES FOR INDUCING HOMOLOGOUS RECOMBINATION EX VIVO AND IN TOTO IN VERTEBRATE SOMATIC TISSUES AND APPLICATION THEREOF
#97USE OF MEGANUCLEASES FOR INDUCING HOMOLOGOUS RECOMBINATION EX VIVO AND IN TOTO IN VERTEBRATE SOMATIC TISSUES AND APPLICATION THEREOF
#98Use of meganucleases for inducing homologous recombination ex vivo and in toto in vertebrate somatic tissues and application thereof
#99Recombinant RSV Virus Expression Systems And Vaccines
#100USE OF MEGANUCLEASES FOR INDUCING HOMOLOGOUS RECOMBINATION EX VIVO AND IN TOTO IN VERTEBRATE SOMATIC TISSUES AND APPLICATION THEREOF
#101USE OF MEGANUCLEASES FOR INDUCING HOMOLOGOUS RECOMBINATION EX VIVO AND IN TOTO IN VERTEBRATE SOMATIC TISSUES AND APPLICATION THEREOF
#102USE OF MEGANUCLEASES FOR INDUCING HOMOLOGOUS RECOMBINATION EX VIVO AND IN TOTO IN VERTEBRATE SOMATIC TISSUES AND APPLICATION THEREOF
#103Use of meganucleases for inducing homologous recombination ex vivo and in toto in vertebrate somatic tissues and application thereof
#104Multi plasmid system for the production of influenza virus
#105CONTROL OF GENE EXPRESSION
#106EXPRESSION OF HIV POLYPEPTIDES AND PRODUCTION OF VIRUS-LIKE PARTICLES
#107Transgenic avians and protein production
#108Use of triplex structure DNA in transferring nucleotide sequences
#109Use of triplex structure DNA in transferring nucleotide sequences
#110IMMUNOGENIC COMPOSITION AND METHODS
#111Multi plasmids system for the production of influenza virus
#112Therapeutic Antibody Target Validation and Screening In Vivo
#113RECOMBINANT POXVIRUS EXPRESSING HOMOLOGOUS GENES INSERTED INTO THE POXVIRAL GENOME
#114Chimeric gene constructs for generation of fluorescent transgenic ornamental fish
#115CUSTOM-MADE MEGANUCLEASE AND USE THEREOF
#116Synthetic genes and genetic constructs
#117Recombinant poxvirus expressing homologous genes inserted
#118Use of triplex structure DNA in transferring nucleotide sequences
#119Intergenic regions as insertion sites in the genome of modified vaccinia virus ankara (MVA)
#120CHROMOSOME-BASED PLATFORMS
#121Gene delivery system and method of use
#122Methods for Conditional and Inducible Transgene Expression to Direct the Development of Embryonic, Embryonic Stem, Precursor and Induced Pluripotent Stem Cells
#123Intergenic regions as insertion sites in the genome of modified vaccinia virus ankara (MVA)
#124MULTIPLE RNA POLYMERASE III PROMOTER EXPRESSION CONSTRUCTS
#125Method for generating a stable recombinant modified vaccinia virus ankara (MVA) comprising human immunodeficiency virus (HIV) genes inserted into one or more intergenic regions (IGRs)
#126Recombinant modified vaccinia ankara (MVA) virus containing heterologous DNA inserts encoding human immunodeficiency virus (HIV) antigens inserted into one or more intergenic regions (IGRs)
#127Method for introducing human immunodeficiency virus nucleotide sequences into a cell utilizing modified vaccinia virus Ankara (MVA) recombinants comprising HIV genes inserted into one or more intergenic regions (IGRs)
#128Immunogenic compositions for inducing an immune response to HIV
#129Method for the production of human immunodeficiency virus (HIV) proteins utilizing modified vaccinia virus ankara (MVA) recombinants comprising HIV genes inserted into one or more intergenic regions (IGRs)
#130Selection of host cells expressing protein at high levels
#131Multi-chain eukaryotic display vectors and uses thereof
#132Use of meganucleases for inducing homologous recombination ex vivo and in toto in vertebrate somatic tissues and application thereof
#133Methods and compositions for treating neuropathic and neurodegenerative conditions
#134Multi-chain eukaryotic display vectors and uses thereof
#135Multi-chain eukaryotic display vectors and uses thereof
#136Compositions and methods for identifying antigens which elicit an immune response
#137Polynucleotide constructs, pharmaceutical compositions and methods for targeted downregulation of angiogenesis and anticancer therapy
#138Intergenic regions as insertion sites in the genome of modified vaccinia virus Ankara (MVA)
#139Intergenic regions as insertion sites in the genome of modified vaccinia virus ankara (MVA)
#140MULTICISTRONIC VECTORS AND METHODS FOR THEIR DESIGN
#141Compositions and Methods for Non-Targeted Activation of Endogenous Genes
#142PROMOTERS EXHIBITING ENDOTHELIAL CELL SPECIFICITY AND METHODS OF USING SAME FOR REGULATION OF ANGIOGENESIS
#143Multi-chain eukaryotic display vectors and uses thereof
#144Bovine immunodeficiency virus (BIV) based vectors
#145USE OF MEGANUCLEASES FOR INDUCING HOMOLOGOUS RECOMBINATION EX VIVO AND IN TOTO IN VERTEBRATE SOMATIC TISSUES AND APPLICATION THEREOF
#146SITE-SPECIFIC RECOMBINATION SYSTEMS FOR USE IN EUKARYOTIC CELLS
#147Promoters exhibiting endothelial cell specificity and methods of using same for regulation of angiogenesis
#148Translation enhancer-element dependent vector systems
#149METHOD OF EXPRESSING RECOMBINANT PROTEIN IN CHO CELLS
#150SYSTEM FOR PACKAGING HIGH-CAPACITY ADENOVIRUSES
#151Optimized high yield synthetic plasmids
#152Expression of HIV polypeptides and production of virus-like particles
#153Method for expression of small RNA molecules within a cell
#154Composition and method for imaging stem cells
#155RECOMBINANT POXVIRUS EXPRESSING HOMOLOGOUS GENES INSERTED INTO THE POXVIRAL GENOME
#156RECOMBINANT POXVIRUS EXPRESSING HOMOLOGOUS GENES INSERTED INTO THE POXVIRUS GENOME
#157Protein production method
#158Recombinant RSV Virus Expression Systems And Vaccines
#159Compositions and methods modulating MG29 for the treatment of diabetes
#160Use of regulatory sequences for specific, transient expression in neuronal determined cells
#161Use of regulatory sequences for specific, transient expression in neuronal determined cells
#162Multi-chain eukaryotic display vectors and uses thereof
#163Alphavirus Vectors for Respiratory Pathogen Vaccines
#164RECOMBINANT ALPHAVIRUS-BASED VECTORS WITH REDUCED INHIBITION OF CELLULAR MACRO-MOLECULAR SYNTHESIS
#165Intergenic regions as insertion sites in the genome of modified vaccinia virus ankara (MVA)
#166Vectors for multiple gene expression
#167Single expression vector for generation of a virus with a segmented genome
#168Diphtheria toxin first open reading frame operably linked to an H19 promoter and a diphtheria toxin second open reading frame operably linked to an IGF-II promoter as nucleic acid construct
#169Methods and compositions for treating neuropathic and neurodegenerative conditions
#170Recombinant virus vector originating in HHV-6 or HHV-7, method of producing the same, method of transforming host cell using the same, host cell transformed thereby and gene therapy method using the same
#171Use of triplex structure DNA in transferring nucleotide sequences
#172DNA for eukaryotic expression of CymR
#173Recombinant modified vaccinia virus ankara (MVA) comprising human immunodeficiency virus (HIV) genes inserted into one or more intergenic regions (IGRs)
#174Methods for inducing an immune response in a host comprising administering modified vaccinia virus ankara (MVA) recombinants comprising human immunodeficiency virus (HIV) genes inserted into one or more intergenic regions (IGRs)
#175Eukaryotic layered vector initiation systems
#176RECOMBINANT POXVIRUS EXPRESSING HOMOLOGOUS GENES INSERTED INTO THE POXVIRAL GENOME
#177Recombinant viruses comprising the membrane-proximal domain of VSV G protein
#178Signaling peptides
#179TARGETED TUMOR THERAPY BY USE OF RECOMBINANT ADENOVIRUS VECTORS THAT SELECTIVELY REPLICATE IN HYPOXIC REGIONS OF TUMORS
#180Use of meganucleases for inducing homologous recombination ex vivo and in toto in vertebrate somatic tissues and application thereof
#181In Vivo Production and Delivery of Erythropoietin or Insulinotropin for Gene Therapy
#182Viral vectors
#183Hepatitis C virus vaccine
#184Methods for Conditional and Inducible Transgene Espression to Direct the Development of Embryonic, Embryonic Stem, Precursor and Induced Pluripotent Stem Cells
#185Polynucleotide
#186Promoters exhibiting endothelial cell specificity and methods of using same for regulation of angiogenesis
#187Recombinant influenza viruses expressing tumor-associated antigens as antitumor agents
#188SITE-SPECIFIC RECOMBINATION SYSTEMS FOR USE IN EUKARYOTIC CELLS
#189Methods and compositions relating to improved lentiviral vectors and their applications
#190Recombinant RSV Virus Expression Systems And Vaccines
#191Compositions comprising MG29 nucleic acids, polypeptides, and associated methods of use
#192COMPOSITIONS AND METHODS FOR NON-TARGETED ACTIVATION OF ENDOGENOUS GENES
#193Hybrid-AAV vectors to deliver large gene expression cassette
#194MULTIPLE-COMPARTMENT EUKARYOTIC EXPRESSION SYSTEMS
#195Intergenic regions as insertion sites in the genome of modified vaccinia virus ankara (MVA)
#196Multiple RNA polymerase III promoter expression constructs
#197Recombinant RSV Virus Expression Systems And Vaccines
#198Recombinant viruses and their use for treatment of atherosclerosis and other forms of coronary artery disease and method, reagent, and kit for evaluating susceptibility to same
#199NOVEL EXPRESSION VECTORS AND USES THEREOF
#200Cell line
#201Hepatitis C virus vaccine
#202Antibodies produced in a transgenic avian egg white
#203Multi plasmid system for the production of influenza virus
#204Expression in insect cells of genes with overlapping open reading frames, methods and compositions therefor
#205Mammalian Expression Vector Comprising the MCMV Promoter and First Intron of HCMV Major Immediate Early Gene
#206Method for producing temperature sensitive influenza A viruses
#207RECOMBINANT RSV VIRUS EXPRESSION SYSTEMS AND VACCINES
#208Use of regulatory sequences for specific, transient expression in neuronal determined cells
#209Tissue Specific Expression of Exogenous Proteins in Transgenic Chickens
#210Inducible eukaryotic expression system
#211Recombinant adenoviruses preparation and adenovirus banks
#212MULTICISTRONIC VECTORS AND METHODS FOR THEIR DESIGN
#213Alphavirus Vectors for Respiratory Pathogen Vaccines
#214Bovine immunodeficiency virus (BIV) based vectors
#215Novel method for integrating genes at specific sites in mammalian cells via homologous recombination and vectors for accomplishing the same
#216Methods and compositions for genomic modification
#217High-efficiency wild-type-free AAV helper functions
#218TRANSGENIC ORGANISM
#219Treatment of HSV-related pathologies using plasmids that make ssDNA
#220Replication competent hepatitis C virus and methods of use
#221Polynucleotide constructs, pharmaceutical compositions and methods for targeted downregulation of angiogenesis and anticancer therapy
#222Recombinant RSV Virus Expression Systems And Vaccines
#223Expression of HIV polypeptides and production of virus-like particles
#224Methods of treating neoplasia with combination target cell-specific adenovirus, chemotherapy and radiation
#225Methods and compositions for synthesis of nucleic acid molecules using multiple recognition sites
#226Administration of transposon-based vectors to reproductive organs
#227Gene regulation in transgenic animals using a transposon-based vector
#228Vectors for tissue-specific replication
#229Stable adenoviral vectors and methods for propagation thereof
#230Complementing cell lines
#231CODON OPTIMIZED SYNTHETIC PLASMIDS
#232Efficient production of F(ab')fragments in mammalian cells
#233Method of expressing recombinant protein in CHO cells
#234Method for producing transgenic rats
#235Compositions and methods for identifying antigens which elicit an immune response
#236Vectors for tissue-specific replication
#237Expression vector for animal cell comprising at least one copy of MAR DNA sequences at the 3′ terminal of transcription termination region of a gene and method for the expression of foreign gene using the vector
#238Methods of using BCL-2 for the therapeutic treatment and prevention of diseases
#239Vectors for tissue-specific replication
#240Sale of fluorescent transgenic ornamental fish
#241Method for expression of small antiviral RNA molecules within a cell
#242Means and methods for producing a stabilized cell of interest
#243Rescue of mumps virus from CDNA
#244Rescue of mumps virus from cDNA
#245Polyvalent Viral Vectors and a System for Production Thereof
#246Bovine immunodeficiency virus (BIV) based vectors
#247Peripherally delivered glutamic acid decarboxylase gene therapy for spinal cord injury pain
#248Methods and compositions relating to restricted expression lentiviral vectors and their applications
#249Plasmid having three complete transcriptional units and immunogenic compositions for inducing an immune response to hiv
#250GM-CSF gene therapy for Crohn's disease using an improved regulated expression system
#251Compositions and methods for non-targeted activation of endogenous genes
#252Herpes simplex virus vector
#253Method for growing stem cells on genetically modified supporter cells
#254HUMAN DISEASE MODELING USING SOMATIC GENE TRANSFER
#255Immunogenic composition and methods
#256Compositions and methods for non-targeted activation of endogenous genes
#257Compositions and methods for non-targeted activation of endogenous genes
#258Use of regulatory sequences for specific, transient expression in neuronal determined cells
#259Peptide protein translation inhibitor and the use thereof for protein translation control
#260Multiple gene transcription activity assay system
#261hTMC promoter and vectors for the tumor-selective and high-efficient expression of cancer therapeutic genes
#262Vectors for tissue-specific replication
#263Production of recombinant AAV using adenovirus comprising AAV rep/cap genes
#264Method for creating myeloid cell lines
#265Expression Vectors and Methods
#266Compositions and methods for generating an immune response
#267Translation enhancer-element dependent vector systems
#268Expression Vectors and Methods
#269Polynucleotides for use in recombinant adeno-associated virus virion production
#270Production of pseudotyped recombinant AAV virions
#271Transgenic rodents as animal models for modulation of B1 bradykinin receptor protein
#272Compositions and methods for helper-free production of recombinant adeno-associated viruses
#273Treatment of disease using an improved regulated expression system
#274Recombinant modified adenovirus fiber protein
#275High-titer retroviral packaging cells
#276Cell lines for production of replication-defective adenovirus
#277Regulated vectors for selection of cells exhibiting desired phenotypes
#278Production of hSA-linked butyrylcholinesterases in transgenic mammals
#279Inducible alphaviral/orip based gene expression system
#280Chromosome-based platforms
#281Cell-specific molecule and method for importing DNA into osteoblast nuclei
#282Full-length genomic RNA of Japanese encephalitis virus, infectious JEV cDNA therefrom, and use thereof
#283Nucleotide sequence for treating cancer and infection
#284Efficient generation of adenovirus-based libraries by positive selection of adenoviral recombinants through ectopic expression of the adenovirus protease
#285Custom-made meganuclease and use thereof
#286Amplifiable adeno-associated virus (AAV) packaging cassettes for the production of recombinant AAV vectors
#287Flavivirus vaccine delivery system
#288Lentiviral vectors carrying synthetic bi-directional promoters and uses thereof
#289Selection of host cells expressing protein at high levels
#290Optimized high yield synthetic plasmids
#291Intergenic regions as novel sites for insertion of HIV DNA sequences in the genome of Modified Vaccinia virus Ankara
#292Viral vectors
#293Glycosylated interferon α
#294Avians that produce eggs containing exogenous proteins
#295Production of exogenous proteins in egg whites of transgenic chickens
#296Multiple-compartment eukaryotic expression systems
#297Gene trap system
#298Glycosylated interferon alpha obtained from a transgenic chicken
#299Recombinant poxvirus expressing homologous genes inserted into the foxviral genome
#300Nucleic acid sequences encoding proteins capable of associating into a virus-like particle