112327 ⎘
Vectors comprising a special translation-regulating system being a specific part of the splice mechanism, e.g. donor, acceptor
Sub-classes:GENE THERAPY VECTORS FOR TREATMENT OF CANCER
#2DELIVERY OF HETEROLOGOUS PROTEINS
#3COMPOSITIONS AND METHODS FOR TREATING SENSORINEURAL HEARING LOSS USING OTOFERLIN DUAL VECTOR SYSTEMS
#4REGULATION OF GENE EXPRESSION BY APTAMER-MEDIATED MODULATION OF ALTERNATIVE SPLICING
#5ADENOVIRAL CHIMERIC TDP-43 PROTEINS
#6ADENO-ASSOCIATED VIRUS VECTOR VARIANTS FOR HIGH EFFICIENCY GENOME EDITING AND METHODS THEREOF
#7Expression Cassette for Production of High-Expression and High-Functionality Target Protein and Use Thereof
#8NON-VIRAL B CELL ENGINEERING METHODS
#9ADENOVIRUS ARMED WITH BISPECIFIC T CELL ACTIVATOR
#10RECOMBINANT COAGULATION FACTOR VIII AND USE THEREOF
#11COMPOSITIONS AND METHODS FOR TREATING SENSORINEURAL HEARING LOSS USING STEREOCILIN DUAL VECTOR SYSTEMS
#12Adenovirus armed with bispecific T cell activator
#13METHODS AND COMPOSITIONS TO CONFER REGULATION TO GENE THERAPY CARGOES BY HETEROLOGOUS USE OF ALTERNATIVE SPLICING CASSETTES
#14SELF-LIMITING, SEX-SPECIFIC GENE AND METHODS OF USING
#15Gene Expression System
#16COMPOSITIONS AND METHODS FOR MAMMALIAN GENETICS AND USES THEREOF
#17Adeno-associated virus vector variants for high efficiency genome editing and methods thereof
#18COMPOSITIONS AND METHODS FOR CIRCULAR RNA EXPRESSION
#19REGULATION OF GENE EXPRESSION BY APTAMER-MEDIATED MODULATION OF ALTERNATIVE SPLICING
#20Adeno-associated viral chimeric TDP-43 proteins
#21COMPOSITIONS AND METHODS FOR TREATING SENSORINEURAL HEARING LOSS USING OTOFERLIN DUAL VECTOR SYSTEMS
#22METHODS FOR MODIFYING A GENOME
#23REAGENTS AND METHODS FOR MODULATING CONE PHOTORECEPTOR ACTIVITY
#24MULTIPLE VECTOR SYSTEM AND USES THEREOF
#25COMPOSITIONS AND METHODS FOR TREATING SENSORINEURAL HEARING LOSS USING OTOFERLIN DUAL VECTOR SYSTEMS
#26CIRCULARIZED ENGINEERED RNA AND METHODS
#27Enhanced promoter
#28Gene expression system
#29Adeno-associated virus vector variants for high efficiency genome editing and methods thereof
#30Self-limiting, sex-specific gene and methods of using
#31Expression cassette for production of high-expression and high-functionality target protein and use thereof
#32Adenovirus armed with bispecific T cell activator
#33Regulation of gene expression by aptamer-mediated modulation of alternative splicing
#34Vector for targeting the human Rosa26 gene
#35Enhanced production of recombinant proteins by transient transfection of suspension-growing mammalian cells
#36Multifunctional alleles
#37Compositions and methods for mammalian genetics and uses thereof
#38Adenovirus armed with bispecific T cell engager
#39Oncolytic group B adenovirus expressing a stroma-targeted bispecific t-cell engager
#40Methods of modifying genes in eukaryotic cells
#41Reagents and methods for modulating cone photoreceptor activity
#42LENTIVIRAL VECTORS AND USES THEREOF
#43Adeno-associated virus vector variants for high efficiency genome editing and methods thereof
#44Gene expression system using alternative splicing in insects
#45INTRACELLULAR TRANSLATION OF CIRCULAR RNA
#46Regulation of gene expression by aptamer-mediated modulation of alternative splicing
#47STEM CELL GENE TARGETING
#48GENE EXPRESSION SYSTEM
#49Adeno-associated virus vector variants for high efficiency genome editing and methods thereof
#50Gene expression system using alternative splicing in insects
#51Intracellular translation of circular RNA
#52Effective delivery of large genes by dual AAV vectors
#53Stem cell gene targeting
#54REAGENTS AND METHODS FOR MODULATING CONE PHOTORECEPTOR ACTIVITY
#55Methods and compositions relating to improved lentiviral vector production systems
#56Nucleic acid construct and use of the same
#57Gene targeting vector, and method for using same
#58Methods and compositions relating to restricted expression lentiviral vectors and their applications
#59Vectors harboring toxic genes, methods and uses therefor
#60Reversible gene expression
#61Reagents and methods for modulating cone photoreceptor activity
#62Multifunctional alleles
#63USE OF MEGANUCLEASES FOR INDUCING HOMOLOGOUS RECOMBINATION EX VIVO AND IN TOTO IN VERTEBRATE SOMATIC TISSUES AND APPLICATION THEREOF
#64USE OF MEGANUCLEASES FOR INDUCING HOMOLOGOUS RECOMBINATION EX VIVO AND IN TOTO IN VERTEBRATE SOMATIC TISSUES AND APPLICATION THEREOF
#65Use of meganucleases for inducing homologous recombination ex vivo and in toto in vertebrate somatic tissues and application thereof
#66Alternative splicing constructs and methods of use
#67USE OF MEGANUCLEASES FOR INDUCING HOMOLOGOUS RECOMBINATION EX VIVO AND IN TOTO IN VERTEBRATE SOMATIC TISSUES AND APPLICATION THEREOF
#68USE OF MEGANUCLEASES FOR INDUCING HOMOLOGOUS RECOMBINATION EX VIVO AND IN TOTO IN VERTEBRATE SOMATIC TISSUES AND APPLICATION THEREOF
#69USE OF MEGANUCLEASES FOR INDUCING HOMOLOGOUS RECOMBINATION EX VIVO AND IN TOTO IN VERTEBRATE SOMATIC TISSUES AND APPLICATION THEREOF
#70Use of meganucleases for inducing homologous recombination ex vivo and in toto in vertebrate somatic tissues and application thereof
#71METHOD AND COMPOSITION FOR CREATING CONDITIONAL LETHALITY FOR VIRUS MUTANTS AND FOR ELIMINATING THE VIABILITY OF AN EUKARYOTIC CELL
#72Viral Vectors with Improved Properties
#73COMPOSITIONS AND METHODS FOR MAMMALIAN GENETICS AND USES THEREOF
#74REAGENTS AND METHODS FOR MODULATING CONE PHOTORECEPTOR ACTIVITY
#75CUSTOM-MADE MEGANUCLEASE AND USE THEREOF
#76Nucleic acids encoding modified Ebola virus glycoproteins with diminished cytotoxicity while retaining native antigenic structures
#77Helper-free Rescue of Recombinant Negative Strand RNA Virus Systems
#78CDNA corresponding to the antigenome of nonsegmented negative strand RNA viruses, and process for the production of such viruses encoding additional antigenically active proteins
#79Use of meganucleases for inducing homologous recombination ex vivo and in toto in vertebrate somatic tissues and application thereof
#80Immunoglobulin display vectors
#81Compositions and Methods for Non-Targeted Activation of Endogenous Genes
#82Compositions and methods for detecting and modulating cell death by a translation regulated gene expression system
#83USE OF MEGANUCLEASES FOR INDUCING HOMOLOGOUS RECOMBINATION EX VIVO AND IN TOTO IN VERTEBRATE SOMATIC TISSUES AND APPLICATION THEREOF
#84Multifunctional Alleles
#85Method for performing genetic modification under a drug-free environment and components thereof
#86CODON OPTIMIZED CFTR
#87RECOMBINANT ALPHAVIRUS-BASED VECTORS WITH REDUCED INHIBITION OF CELLULAR MACRO-MOLECULAR SYNTHESIS
#88Methods and compositions for regulated expression of multiple nucleic acids
#89Methods and Compositions for Regulated Expressions of Nucleic Acid at Post-Transcriptional Level
#90Eukaryotic layered vector initiation systems
#91Use of meganucleases for inducing homologous recombination ex vivo and in toto in vertebrate somatic tissues and application thereof
#92In Vivo Production and Delivery of Erythropoietin or Insulinotropin for Gene Therapy
#93Polynucleotide
#94Methods of treating anemia using recombinant adeno-associated virus virions
#95Methods and compositions relating to improved lentiviral vector production systems
#96Targeting the Rosa26 gene in human embryonic stem cells
#97COMPOSITIONS AND METHODS FOR NON-TARGETED ACTIVATION OF ENDOGENOUS GENES
#98Methods and Constructs for Expressing Polypeptide Multimers in Eukaryotic Cells Using Alternative Splicing
#99Hybrid-AAV vectors to deliver large gene expression cassette
#100Expression vectors
#101Recombinant viruses and their use for treatment of atherosclerosis and other forms of coronary artery disease and method, reagent, and kit for evaluating susceptibility to same
#102Expression of heterologous genes according to a targeted expression profile
#103Recombinant expression vectors comprising a human codon-optimized marburg virus (MARV) angola glycoprotein gene insert and method of immunization employing said vector
#104Antibodies produced in a transgenic avian egg white
#105Methods of treating anemia using recombinant adeno-associated virus virions
#106Generation of tumor-free embryonic stem-like pluripotent cells using inducible recombinant RNA agents
#107GENE EXPRESSION SYSTEM USING ALTERNATIVE SPLICING IN INSECTS
#108ENRICHED PREPARATION OF HUMAN FETAL MULTIPOTENTIAL NEURAL STEM CELLS
#109Indexed library of cells containing genomic modifications and methods of making and utilizing the same
#110Vectors capable of immortalizing non-dividing cells and cells immortalized with said vectors
#111Immunoglobulin display vectors
#112Genetically Engineered and Photyped Mice and Stem Cell Clones for Producing the Same
#113Recombinant negative strand RNA virus expression systems and vaccines
#114Novel method for integrating genes at specific sites in mammalian cells via homologous recombination and vectors for accomplishing the same
#115TRANSGENIC ORGANISM
#116Methods for delivering DNA to muscle cells using recombinant adeno-associated virus virions
#117Stable adenoviral vectors and methods for propagation thereof
#118Methods for delivering DNA to muscle cells using recombinant adeno-associated virus vectors
#119RGMc modified transgenic animals
#120Method for producing transgenic rats
#121cDNA corresponding to the antigenome of nonsegmented negative stranded RNA viruses and process for the production of such viruses
#122Methods for delivering DNA to muscle cells using recombinant adeno-associated virus virions vectors
#123Modified Cells and Methods of Using Same
#124Isolation, selection and propagation of animal transgenic stem cells
#125ANTI-INFECTIVE THERAPY
#126Infectious recombinant paramyxovirus from antigenomic cDNA
#127Methods of modifying genes in eukaryotic cells
#128Txr1 and enhanced taxane sensitivity based on the modulation of a pathway mediated thereby
#129Methods and compositions relating to restricted expression lentiviral vectors and their applications
#130Compositions and methods for non-targeted activation of endogenous genes
#131Self-rearranging DNA vectors
#132Adenovirus packaging cell lines
#133Flp-mediated recombination
#134Hiv-dependent expression constructs and uses therefor
#135Compositions and methods for non-targeted activation of endogenous genes
#136Compositions and methods for non-targeted activation of endogenous genes
#137Method for creating fusion protein and conditional alleles
#138Expression Vectors and Methods
#139Expression Vectors and Methods
#140Addition of transgenes into adenoviral vectors
#141Viral vectors with improved properties
#142Cell lines for production of replication-defective adenovirus
#143Methods and compositions for use in spliceosome mediated RNA trans-splicing
#144Induction of immune response to antigens expressed by recombinant adeno-associated virus
#145Custom-made meganuclease and use thereof
#146Methods and compositions for modulating angiogenesis
#147Glycosylated interferon α
#148Avians that produce eggs containing exogenous proteins
#149Production of exogenous proteins in egg whites of transgenic chickens
#150Gene trap system
#151Highly efficient gene targeting vectors and methods for gene targeting method forward epithelial cell line
#152Glycosylated interferon alpha obtained from a transgenic chicken
#153Use of meganucleases for inducing homologous recombination ex vivo and in toto in vertebrate somatic tissues and application thereof
#154Method of producing an exogenous protein in the egg of a chicken
#155Compositions and methods for non-targeted activation of endogenous genes
#156Recombinant adeno-associated virus virions for the treatment of lysosomal disorders
#157Methods of treating anemia using recombinant adeno-associated virus virions
#158Methods for delivering DNA to muscle cells using recombinant adeno-associated virus virions vectors
#159Methods and compositions for use in spliceosome mediated RNA trans-splicing in plants
#160Transgenic chickens producing exogenous protein in eggs
#161Mammalian genes involved in rapamycin resistance and tumorgenesis annexin XIII genes
#162Adenovirus packaging cell lines
#163Integration vectors
#164Retroviral vectors
#165RETROVIRAL VECTORS WITH ENHANCED EFFICIENCY OF TRANSGENE EXPRESSION AND SAFETY
#166Lentiviral vectors and uses thereof
#167Coordinate in vivo gene expression
#168Stable bactericidal/permeability-increasing protein products and pharmaceutical compositions containing the same
#169Transgenic cell and gene recombinant animal having a mutant SDHC gene derived from mammals
#170Use of interfering RNA in the production of transgenic animals
#171Methods and compositions for increasing viral vector production in packaging cell lines
#172Frog prince, a transposon vector for gene transfer in vertebrates
#173Methods and constructs for expressing polypeptide multimers in eukaryotic cells using alternative splicing
#174Compositions and methods for determining anti-viral drug susceptibility and resistance and anti-viral drug screening
#175Production of recombinant polypeptides by bovine species and transgenic methods
#176Isolation, selection and propagation of animal transgenic stem cells
#177Methods for detecting metalloproteinase inhibitors
#178Cytomegalovirus Intron A fragments
#179Polynucleotide
#180Anti-neoplastic viral agents
#181Enhanced production of recombinant proteins by transient transfection of suspension-growing mammalian cells
#182Recombinant viruses and their use for treatment of atherosclerosis and other forms of coronary artery disease and method, reagent, and kit for evaluating susceptibility to same
#183Stable adenoviral vectors and methods for propagation thereof
#184Prkag3 gene promoter and uses thereof
#185Expression vector
#186Method for comprehensive identification of cell lineage specific genes
#187In vivo production and delivery of erythropoietin or insulinotropin for gene therapy
#188DNA construct for effecting homologous recombination and uses thereof
#189Viral vector
#190Vectors for gene mutagenesis and gene discovery
#191Vectors for making genomic modifications
#192Cytomegalovirus Intron A fragments
#193SiRNA mediated gene silencing in transgenic animals
#194Adenoviral vector with replication-dependent transgene expression
#195Vectors and methods for the mutagenesis of mammalian genes
#196Persistent expression of candidate molecule in proliferating stem and progenitor cells for delivery of therapeutic products
#197Enzymatically active recombinant glucocerebrosidase
#198Intron fusion construct and method of using for selecting high-expressing production cell lines
#199Enzymatically active recombinant glucocerebrosidase
#200Retroviral vectors comprising a functional splice donor site and a functional splice acceptor site
#201Human DNase
#202Expression vectors and methods
#203Adenovirus packaging cell lines
#204Genome mutation by intron insertion into an embryonic stem cell genome
#205Adenoviral E1A/E1B complementing cell line
#206Method for producing transgenic animals