TARGETED GENOME MODIFICATION USING CIRCULAR SINGLE-STRANDED DNA

Compositions and Methods for Targeted Delivery of CRISPR-CAS Effector Polypeptides and Transgenes

CIRCULAR RNAS FOR CELLULAR THERAPY

ENGINEERED ENVELOPED VECTORS AND METHODS OF USE THEREOF

REPROGRAMABLE TNPB POLYPEPTIDES AND USE THEREOF

TRANSGENIC T CELL AND CHIMERIC ANTIGEN RECEPTOR T CELL COMPOSITIONS AND RELATED METHODS

SIMULTANEOUS GENE EDITING AND HAPLOID INDUCTION

PRECISION-BASED IMMUNO-MOLECULAR AUGMENTATION (PBIMA) COMPUTERIZED SYSTEM, METHOD, AND THERAPEUTIC VACCINE

METHODS FOR INCREASING THE EFFICIENCY OF HOMOLOGY DIRECTED REPAIR (HDR) IN THE CELLULAR GENOME

PLASTID TRANSFORMATION BY COMPLEMENTATION OF PLASTID MUTATIONS

INCREASING GENE EDITING AND SITE-DIRECTED INTEGRATION EVENTS UTILIZING MEIOTIC AND GERMLINE PROMOTERS

COMPOSITIONS AND METHODS FOR TRANSGENE EXPRESSION FROM AN ALBUMIN LOCUS

METHOD FOR DIGESTING NUCLEIC ACID IN A SAMPLE

Polynucleotides, Compositions, and Methods for Genome Editing

RNA-Guided Endonuclease Fusion Polypeptides and Methods of Use Thereof

MATERIALS AND METHODS FOR REDOSING SUBJECTS RECEIVING GENE INSERTION THERAPEUTICS

METHODS OF TREATING AN ISCHEMIC DISEASE

METHODS AND COMPOSITIONS FOR TRANSGENE DELIVERY AND/OR RECONSTITUTING MICROGLIA

TRANSIENT REPORTERS AND METHODS FOR BASE EDITING ENRICHMENT

LYMPHOCYTE MEDIATED DELIVERY OF INTRACELLULAR TARGET-SPECIFIC PROTEINS

EUKARYOTE QUADRUPLET EXPANDED DNA (QED) GENETIC CODE

METHOD FOR TARGETED ALTERATION OF DUPLEX DNA

ENGINEERED MUSCLE TARGETING COMPOSITIONS

COUNTER-SELECTION BY INHIBITION OF CONDITIONALLY ESSENTIAL GENES

COMPOSITIONS AND METHODS FOR TREATING ALPHA-1 ANTITRYPSIN DEFICIENCY

ANALYSIS SYSTEM FOR ORTHOGONAL ACCESS TO AND TAGGING OF BIOMOLECULES IN CELLULAR COMPARTMENTS

Compositions and Methods for Kallikrein (KLKB1) Gene Editing

RNA-GUIDED NUCLEASES AND ACTIVE FRAGMENTS AND VARIANTS THEREOF AND METHODS OF USE

OPTIMIZED ENGINEERED MEGANUCLEASES HAVING SPECIFICITY FOR THE HUMAN T CELL RECEPTOR ALPHA CONSTANT REGION GENE

REPROGRAMMABLE ISCB NUCLEASES AND USES THEREOF

SUPPLEMENTATION OF LIVER ENZYME EXPRESSION

SUPPLEMENTATION OF LIVER ENZYME EXPRESSION

SUPPLEMENTATION OF LIVER ENZYME EXPRESSION

METHODS OF PREPARING MITOCHONDRIA REPLACED CELLS WITH IMPROVED MITOCHONDRIAL FUNCTION

METHOD FOR CREATING MALE STERILE AND MAINTAINER DUAL-PURPOSE LINE BY KNOCKING OUT BnOPR3 GENE IN BRASSICA NAPUS

PHAGE-DERIVED PARTICLES FOR IN SITU DELIVERY OF DNA PAYLOAD INTO C. ACNES POPULATION

RNA-GUIDED DNA INTEGRATION USING TN7-LIKE TRANSPOSONS

HIGH-THROUGHPUT COMBINATORIAL GENETIC MODIFICATION SYSTEM AND OPTIMIZED CAS9 ENZYME VARIANTS

METHODS OF TREATING PULMONARY SARCOIDOSIS WITH DNA NUCLEASES

CATIONIC LIPID COMPOSITIONS FOR TISSUE-SPECIFIC DELIVERY

Drug-Resistant Immune Cells and Methods of Use Thereof

COMPOSITIONS AND METHODS FOR TREATING HEMOGLOBINOPATHIES

REGULATION OF CELLS AND ORGANISMS

VECTOR FOR MULTI-GENE BASE EDITING, EDITING METHOD, AND USE

TARGETED GENE INSERTION FOR IMPROVED IMMUNE CELLS THERAPY

CRISPR AND AAV STRATEGIES FOR X-LINKED JUVENILE RETINOSCHISIS THERAPY

Gene Therapy for Genetic and Acquired Vasculopathies

RNA GUIDED ERADICATION OF HERPES SIMPLEX TYPE I AND OTHER RELATED HERPESVIRUSES

IMMUNE CELLS EXPRESSING ENGINEERED ANTIGEN RECEPTORS

CRISPR/CPF1 Systems and Methods

LIPID-ENCAPSULATED DUAL-CLEAVING ENDONUCLEASE FOR DNA AND GENE EDITING

GENE EDITING-BASED METHOD OF ATTENUATING THE BETA-AMYLOID PATHWAY

REGULATION OF CELLS AND ORGANISMS

AMPLICON-DEPLETED CRISPR/CAS-REGULATED ISOTHERMAL MOLECULAR ASSAY AT SKIN TEMPERATURE ENABLING MULTI-LEVEL, EQUIPMENT-FREE, HOME-BASED SELF-TESTING OF VIRAL INFECTIONS

METHODS OF IMMORTALIZING PRIMARY RESTING T CELLS BY CRISPR/DCAS9-BASED EPIGENETIC MODIFIERS AND TRANSCRIPTIONAL ACTIVATORS

INSECT RESISTANT INIR6 TRANSGENIC MAIZE PLANTS LACKING A SELECTABLE MARKER AND JUNCTION

METHODS FOR IMPROVING THE HEALTH OF PORCINE SPECIES BY TARGETED INACTIVATION OF CD163

Method to Rejuvenate Human Cells Through Transcriptional Reprogramming

KIT FOR RAPID DETECTION OF AVIAN LEUKOSIS VIRUS SUBGROUP J BASED ON CRISPR/Cas13a SYSTEM

CHIMERIC TRANSPOSASES AND USES THEREOF

COMPOSITIONS AND METHODS FOR TREATING, AMELIORATING, AND/OR PREVENTING DISEASES AND/OR DISORDERS

Differential Knockout of an Allele of a Heterozygous Elane Gene

Materials and Methods for Treatment of Pain Related Disorders

METHODS AND PRODUCTS FOR EXPRESSING PROTEINS IN CELLS

ENDONUCLEASE SYSTEMS

METHODS AND PRODUCTS FOR TRANSFECTING CELLS

SCARLESS GENOME EDITING THROUGH TWO-STEP HOMOLOGY DIRECTED REPAIR

METHODS FOR CONTROLLING MERISTEM SIZE FOR CROP IMPROVEMENT

METHODS AND COMPOSITIONS FOR IMPROVING PLANT ARCHITECTURE AND YIELD TRAITS

INSECT RESISTANT INIR6 TRANSGENIC MAIZE PLANTS LACKING A SELECTABLE MARKER AND JUNCTION

Treatment Of Sepsis With PCSK9 And LDLR Modulators

ENGINEERED PROTEINS AND METHODS OF USE THEREOF

POLYPEPTIDES

RNA PROGRAMMABLE EPIGENETIC RNA MODIFIERS AND USES THEREOF

HLA Triple Knockout Human Follicle Cells for Enhanced Hair Implantation Therapy with Integrated Biosensor System

METHOD FOR PRODUCING A COMPUTATIONAL REDUCTION VACCINE

METHODS OF INDUCING SITE-SPECIFIC CLEAVAGE OF RNA POLYNUCLEOTIDES WITH T2 FAMILY RIBONUCLEASES

ENGINEERED MUSCLE TARGETING COMPOSITIONS

GUIDE POLYNUCLEOTIDE MULTIPLEXING

COMPOSITIONS, KITS, AND METHODS FOR ANALYSIS OF DNA SEQUENCE-SPECIFICITY IN V(D)J RECOMBINATION

NUCLEOBASE EDITORS AND METHODS OF USE THEREOF

CRISPR ENZYMES AND SYSTEMS WITH MODIFIED PAM SPECIFICITY

ENGINEERED CASCADE COMPONENTS AND CASCADE COMPLEXES

GENE EDITING FOR THE TREATMENT OF EPIDERMOLYSIS BULLOSA

CELL MEMBRANE PENETRATING CONJUGATES FOR GENE EDITING

METHODS FOR IMPROVING PRODUCTION OF BIOLOGICAL PRODUCTS BY REDUCING THE LEVEL OF ENDOGENOUS PROTEIN

Hyperactive variants of the transposase protein of the transposon system Sleeping Beauty

SIRPalpha-SILENCED NATURAL KILLER (NK) CELLS

METHODS FOR TREATING ACUTE CORONARY SYNDROME USING APOA-1 FUSION PROTEINS

COMPOSITIONS AND METHODS FOR TREATING HEMOGLOBINOPATHIES

LENTIVIRUS WITH ALTERED INTEGRASE ACTIVITY

Differential Knockout of An Allele of A Heterozygous Fibrinogen Alpha Chain (FGA) Gene

CRISPR/CAS9-BASED REPRESSORS FOR SILENCING GENE TARGETS IN VIVO AND METHODS OF USE

EVOLVED INTEGRASES AND METHODS OF USING THE SAME FOR GENOME EDITING

CELL-BASED ASSAY FOR QUANTIFYING THE POTENCY AND EFFICACY OF CANNABINOIDS AND/OR TERPENOIDS, AND METHODS OF USE THEREOF

METHODS AND COMPOSITIONS FOR SEQUENCING LIBRARY NORMALIZATION

METHODS AND PRODUCTS FOR TRANSFECTING CELLS

ABCA4 TRANS-SPLICING MOLECULES

COMPOSITIONS FOR AND METHODS OF EDITING THE GENOME

CRISPR/CAS SCREENING PLATFORM TO IDENTIFY GENETIC MODIFIERS OF TAU SEEDING OR AGGREGATION

Targeting Nrip1 to Alleviate Metabolic Disease

USE OF SmABCG2 GENE IN CULTIVATION OF MALE STERILE LINES IN EGGPLANT

Compositions and Methods for Hydroxyacid Oxidase 1 (HAO1) Gene Editing for Treating Primary Hyperoxaluria Type 1 (PH1)

SINGLE BASE SUBSTITUTION PROTEIN, AND COMPOSITION COMPRISING SAME

Therapeutic Nuclease Compositions and Methods

Protected DNA and Methods for the Production Thereof

POD SHATTER TOLERANCE IN BRASSICA PLANTS

Gene Editing System of Escherichia Coli and Gene Editing Method Thereof

Compositions and Methods for Lactate Dehydrogenase (LDHA) Gene Editing

SYSTEMS AND METHODS FOR THE TREATMENT OF HEMOGLOBINOPATHIES

RNA-GUIDED NUCLEASES AND ACTIVE FRAGMENTS AND VARIANTS THEREOF AND METHODS OF USE

SYNTHETIC MINIATURE CRISPR-CAS (CASMINI) SYSTEM FOR EUKARYOTIC GENOME ENGINEERING

THERAPEUTIC NUCLEASE COMPOSITIONS AND METHODS

GENOME EDITING TECHNIQUE

RNA-GUIDED NUCLEASES AND DNA BINDING PROTEINS

ENGINEERED MEGANUCLEASES HAVING SPECIFICITY FOR A RECOGNITION SEQUENCE IN THE HEPATITIS B VIRUS GENOME

METHOD FOR PREPARING ENHANCED CAR-T-CELLS BASED ON INTERFERING OR KNOCKING OUT HUMAN PCSK9 GENE AND APPLICATION THEREOF

Compositions And Methods For Enhancing Adoptive T Cell Therapeutics

COMPOSITION FOR INDUCING DEATH OF CELLS HAVING MUTATED GENE, AND METHOD FOR INDUCING DEATH OF CELLS HAVING MUTATED GENE BY USING COMPOSITION

CRISPR-CAS COMPONENT SYSTEMS, METHODS AND COMPOSITIONS FOR SEQUENCE MANIPULATION

EXPRESSION SYSTEM FOR PRODUCT MANUFACTURING

SINGLE-VECTOR TYPE I VECTORS

SYSTEMS FOR CELL PROGRAMMING AND METHODS THEREOF

BROAD SPECTRUM NANOZYMES

COMPOSITIONS AND METHODS FOR NUCLEIC ACID MODIFICATIONS

Compositions and Methods for Kallikrein (KLKB1) Gene Editing

RECOMBINANT PROTEINS FOR GENE DELIVERY AND INSERTION

NPP1 Fusion Proteins

ENHANCED VIRUS-LIKE PARTICLES AND METHODS OF USE THEREOF FOR DELIVERY TO CELLS

METHODS AND COMPOSITIONS FOR TREATING TUMOR CELLS

Modified Guide RNAs

COMPOSITIONS AND METHODS OF NUCLEIC ACID-TARGETING NUCLEIC ACIDS

ENZYME BASED COMPOSITIONS AND METHODS FOR REMOVING DENTAL CALCULI

COMPOSITIONS FOR EXPOSING FILM-FORMING MICROBES AND METHODS FOR USE OF THE COMPOSITIONS

MODIFYING THE SPECIFICITY OF PLANT NON-CODING RNA MOLECULES FOR SILENCING GENE EXPRESSION

Methods and Kits for Identifying Cancer Treatment Targets

METHODS AND COMPOSITIONS FOR MODIFICATION OF PROTOSPACER ADJACENT MOTIF SPECIFICITY OF CAS12A

SYNTHETIC GENOME EDITING SYSTEM

MODULAR GENETICALLY ENGINEERED CELL AND METHODS OF GENERATION THEREOF

METHODS, COMPOSITIONS AND COMPONENTS FOR CRISPR-CAS9 EDITING OF CBLB IN T CELLS FOR IMMUNOTHERAPY

METHODS AND COMPOSITIONS FOR SELECTIVELY ELIMINATING CELLS OF INTEREST

LACHNOSPIRACEAE SP. CAS12A MUTANTS WITH ENHANCED CLEAVAGE ACTIVITY AT NON-CANONICAL TTTT PROTOSPACER ADJACENT MOTIFS

MICROHOMOLOGY MEDIATED REPAIR OF MICRODUPLICATION GENE MUTATIONS

COMPOSITIONS AND METHODS FOR THE TREATMENT OF CANCER USING A CD8 ENGINEERED T CELL THERAPY

METHODS OF TREATING NON-SYNDROMIC SENSORINEURAL HEARING LOSS

SYSTEMS AND METHODS FOR ULTRA-SPECIFIC AND ULTRA-SENSITIVE NUCLEIC ACID DETECTION

RECOMBINANT TYPE I CRISPR-CAS SYSTEM AND USES THEREOF FOR SCREENING FOR VARIANT CELLS

COMPOSITIONS AND METHODS FOR TARGETING, EDITING, OR MODIFYING GENES

PROTEIN HAVING NUCLEASE ACTIVITY, FUSION PROTEINS AND USES THEREOF

Methods of Identifying Adenosine-to-Inosine Edited RNA

RATIONALLY-DESIGNED MEGANUCLEASES WITH ALTERED SEQUENCE SPECIFICITY AND DNA-BINDING AFFINITY

GENE EDITING COMPOSITIONS AND METHODS OF USE THEREOF

SYSTEM AND METHOD FOR EXTRACTING GUT MICROBIOTA, CLASSIFYING THEIR DESIRABLE & UNDESIRABLE TRAITS, GENETICALLY MODIFYING THEM FOR DESIRED TRAITS & RESEEDING THEM FOR VARIOUS TREATMENTS & OUTCOMES

DETECTION ASSAYS

HIV OR HCV DETECTION WITH CRISPR-CAS13A

DELIVERY, ENGINEERING AND OPTIMIZATION OF SYSTEMS, METHODS AND COMPOSITIONS FOR SEQUENCE MANIPULATION AND THERAPEUTIC APPLICATIONS

POLYPEPTIDE LINKERS FOR USE IN ENGINEERED MEGANUCLEASES

METHODS AND COMPOSITIONS USING ONE-SIDED TRANSPOSITION

Unconstrained Genome Targeting with near-PAMless Engineered CRISPR-Cas9 Variants

RECOMBINANT ENHANCED ANTIVIRAL RESTRICTORS

CRISPR-Cas Enzymes with Enhanced On-Target Activity

SYSTEMS FOR STEM CELL PROGRAMMING AND METHODS THEREOF

DELIVERY, USE AND THERAPEUTIC APPLICATIONS OF THE CRISPR-CAS SYSTEMS AND COMPOSITIONS FOR HBV AND VIRAL DISEASES AND DISORDERS

CRISPR-TRANSPOSON SYSTEMS AND COMPONENTS

CRISPR HYBRID DNA/RNA POLYNUCLEOTIDES AND METHODS OF USE

MODULAR SYSTEM FOR GENE AND PROTEIN DELIVERY BASED ON AAV

METHODS FOR CONTROLLING MERISTEM SIZE FOR CROP IMPROVEMENT

TYPE I CRISPR SYSTEM AS A TOOL FOR GENOME EDITING

METHODS AND PRODUCTS FOR GENETIC ENGINEERING

CONTINUOUS IN VITRO TRANSCRIPTION PROCESS AND APPARATUS

SUBSTRATE CLEAVAGE FOR NUCLEIC ACID SYNTHESIS

HOMING ENDONUCLEASE VARIANTS

COMPOSITIONS AND METHODS FOR RNA-TEMPLATED EDITING IN PLANTS

SHP INHIBITOR COMPOSITIONS AND USES FOR CHIMERIC ANTIGEN RECEPTOR THERAPY

NUCLEOBASE EDITING SYSTEM AND METHOD OF USING SAME FOR MODIFYING NUCLEIC ACID SEQUENCES

NOVEL ZINC FINGER FUSION PROTEINS FOR NUCLEOBASE EDITING

TARGETED REPLACEMENT OF ENDOGENOUS T CELL RECEPTORS

SYSTEMS, METHODS, AND COMPOSITIONS FOR TREATING VASCULAR DISEASE

Type V CRISPR/CAS Effector Proteins for Cleaving ssDNAs and Detecting Target DNAs

TARGETING PEPTIDE TO DELIVER A COMPOUND TO OOCYTES

CIS CONJUGATIVE PLASMID SYSTEM

RNA-GUIDED TRANSCRIPTIONAL REGULATION AND METHODS OF USING THE SAME FOR THE TREATMENT OF BACK PAIN

METHODS AND COMPOSITIONS FOR MODULATING A GENOME

GENE-MODIFYING ENDONUCLEASES

Allosteric Conditional Guide RNAs for Cell-Selective Regulation of CRISPR/Cas

ENGINEERED MEGANUCLEASES HAVING SPECIFICITY FOR A RECOGNITION SEQUENCE IN THE HEPATITIS B VIRUS GENOME

Novel Mutations That Enhance the DNA Cleavage Activity of Acidaminococcus Sp. CPF1

CRISPR/Cas9-Mediated Exon-Skipping Approach for USH2A-Associated Usher Syndrome

FUSION MOLECULES OF RATIONALLY-DESIGNED DNA-BINDING PROTEINS AND EFFECTOR DOMAINS

Stabilized Nucleic Acids Encoding Messenger Ribonucleic Acid (mRNA)

CISH GENE EDITING OF TUMOR INFILTRATING LYMPHOCYTES AND USES OF SAME IN IMMUNOTHERAPY

METHODS AND COMPOSITIONS FOR MODULATING A GENOME

GENE EDITING COMPONENTS, SYSTEMS, AND METHODS OF USE

LENTIVIRAL-BASED VECTORS AND RELATED SYSTEMS AND METHODS FOR EUKARYOTIC GENE EDITING

HI Genes and Normal A Cytotype Combination

ARTIFICIAL DNA REPLISOME AND METHODS OF USE THEREOF

ENGINEERED GLYCOPROTEIN POPULATION AND USES THEREOF

ENGINEERED GLYCOPROTEIN POPULATION AND USES THEREOF

CELLS LACKING B2M SURFACE EXPRESSION AND METHODS FOR ALLOGENEIC ADMINISTRATION OF SUCH CELLS

OPTIMIZED ENGINEERED NUCLEASES HAVING SPECIFICITY FOR THE HUMAN T CELL RECEPTOR ALPHA CONSTANT REGION GENE

DETECTION ASSAYS

Compositions for Inducing Modifications of Target Endogenous Nucleic Acid Sequences in Nucleuses of Eukaryotic Cells

CBLB ENDONUCLEASE VARIANTS, COMPOSITIONS, AND METHODS OF USE

MODIFIED CASCADE RIBONUCLEOPROTEINS AND USES THEREOF

DNA EDITING USING SINGLE-STRANDED DNA

Novel Mutations in Streptococcus Pyogenes CAS9 Discovered by Broad Scanning Mutagenesis Demonstrate Enhancement of DNA Cleavage Activity

TARGETED NON-VIRAL DNA INSERTIONS

COMPOSITIONS, SYSTEMS, AND METHODS FOR REGULATION OF HEPATITIS B VIRUS THROUGH TARGETED GENE REPRESSION

CRISPR-CPF1-RELATED METHODS, COMPOSITIONS AND COMPONENTS FOR CANCER IMMUNOTHERAPY

COMPOSITIONS AND METHODS OF NUCLEIC ACID-TARGETING NUCLEIC ACIDS

NOVEL RNA-PROGRAMMABLE ENDONUCLEASE SYSTEMS AND USES THEREOF

A DNA Assembly Mix And Method Of Uses Thereof

ENGINEERED GENETIC MODULATORS

POLYPEPTIDES

GENETICALLY-MODIFIED CELLS COMPRISING A MODIFIED TRANSFERRIN GENE

GELATIN AND LIPIDOID GENETIC DELIVERY PARTICLE

COMPOSITIONS AND METHODS FOR MODIFYING GENOMES

CRISPR-CAS COMPONENT SYSTEMS, METHODS AND COMPOSITIONS FOR SEQUENCE MANIPULATION

NUCLEIC ACIDS ENCODING CRISPR-ASSOCIATED PROTEINS AND USES THEREOF

IMMOBILIZED ENZYME NANOGEL AND PREPARATION METHOD AND APPLICATION THEREOF

INDUCIBLE RECOMBINASE SYSTEMS

METHODS USING NOVEL CPF1 MUTATIONS THAT ENHANCE THE DNA CLEAVAGE ACTIVITY OF ACIDAMINOCOCCUS SP. CPF1

NUCLEIC ACIDS ENCODING ANCHOR MODIFIED ANTIBODIES AND USES THEREOF

SINGLE-STRANDED END PRESERVING ADAPTORS

LIPID-ENCAPSULATED DUAL-CLEAVING ENDONUCLEASE FOR DNA AND GENE EDITING

Engineering of CAS9 Variants That Possess Targeted Nuclease Activity When Paired with Short SGRNAS

GENETICALLY-MODIFIED PLURIPOTENT STEM CELLS AND DERIVED NATURAL KILLER CELLS AND METHODS FOR PRODUCING THE SAME

USE OF A 53BP1 BINDING HUMAN UBIQUITIN VARIANT TO IMPROVE RATES OF HDR IN MULTIPLE CELL TYPES

ISOLATION OF ANTI-INFLAMMATORY NEUTROPHIL OR MONOCYTE SUBSET AND USE IN TREATING CARDIOVASCULAR DISEASES

MULTIDOMAIN LIGASE ENZYMES WITH RNA-DNA HYBRID DUPLEX BINDING DOMAINS

TARGET-SPECIFIC CRISPR MUTANT

COMPOSITIONS COMPRISING A CRISPR NUCLEASE AND USES THEREOF

GAMMA DELTA T CELL COMPOSITIONS AND METHODS OF USE

ALTERNATIVE SPLICING ENHANCER MOLECULES

NUCLEIC ACID BINDING DOMAINS AND METHODS OF USE THEREOF

COMPOSITIONS AND METHODS FOR PROMOTING HOMOLOGY DIRECTED REPAIR

COMPOSITIONS AND METHODS FOR EPIGENETIC REGULATION OF HBV GENE EXPRESSION

RNA BASE EDITING COMPOSITIONS, SYSTEMS, METHODS AND USES THEREOF

RNA-GUIDED NUCLEASES AND ACTIVE FRAGMENTS AND VARIANTS THEREOF AND METHODS OF USE

SYSTEMS FOR CELL CONTROL

GENE-DRIVE IN DNA VIRUSES

MODULATING LACTOGENIC ACTIVITY IN MAMMALIAN CELLS

SYSTEMS AND METHODS FOR MODULATING RNA

Polypeptides Having Beta-Glucanase Activity, Polynucleotides Encoding Same and Uses Thereof In Cleaning and Detergent Compositions

METHODS FOR PRODUCING A COMPLEX TRANSGENIC TRAIT LOCUS

KNOCKOUT OF A MUTANT ALLELE OF AN ELANE GENE

GENOME EDITING IN PLANTS

METHODS AND COMPOSITIONS FOR RE-DOSING AAV USING ANTI-CD40 ANTAGONISTIC ANTIBODY TO SUPPRESS HOST ANTI-AAV ANTIBODY RESPONSE

Conditional male sterility in wheat

Methods for Suppression of Gene Silencing in Plants

PLANTS WITH ALTERED ROOT AND SHOOT ARCHITECTURE AND METHODS FOR OBTAINING AND USING SAME

METHODS AND COMPOSITIONS FOR IMPROVING YIELD CHARACTERISTICS IN PLANTS

COMPOSITIONS, SYSTEMS, AND METHODS FOR REGULATION OF HEPATITIS B VIRUS THROUGH TARGETED GENE REPRESSION

GUIDE RNAS AND USES THEREOF

NUCLEOBASE EDITORS AND USES THEREOF

A SYNTHETIC SYSTEM FOR TUNABLE THRESHOLDING OF PROTEIN SIGNALS

RT EDITING COMPOSITIONS AND METHODS

METHODS FOR TREATING DILATED CARDIOMYOPATHY AND PHARMACEUTICAL COMPOSITIONS THEREFOR

RNA AND DNA ANALYSIS USING ENGINEERED SURFACES

GENE EDITING OF GBA1 IN STEM CELLS AND METHOD OF USE OF CELLS DIFFERENTIATED THEREFROM

PLASMID ENCODING AN INSULIN PEPTIDE AND Fc FUSION PROTEIN

PLASMID ENCODING A NGF AND Fc FUSION PROTEIN

PLASMID ENCODING A TLR3 AND Fc FUSION PROTEIN

PLASMID ENCODING A DNAse I AND Fc FUSION PROTEIN

PLASMID ENCODING A TLR9 AND Fc FUSION PROTEIN

INIR20 TRANSGENIC SOYBEAN WITH JUNCTION POLYNUCLEOTIDE DELETIONS

CYTOSINE DEAMINASE AND USE THEREOF IN BASE EDITING

NUCLEOBASE EDITORS COMPRISING GEOCAS9 AND USES THEREOF

MUTANT RNASE E FOR ENHANCING RECOMBINANT PROTEIN EXPRESSION

PCSK9 ENDONUCLEASE VARIANTS, COMPOSITIONS, AND METHODS OF USE

DUAL VECTOR SELF-INACTIVATING CRISPR/CAS9 SYSTEM

Targeted DNA Integration in Plants by CRISPR-Associated Transposases (CASTs)

RNA-GUIDED DNA TRANSPOSITION

METHODS FOR NOMINATION OF NUCLEASE ON-/OFF-TARGET EDITING LOCATIONS, DESIGNATED "CTL-seq" (CRISPR Tag Linear-seq)

NUCLEIC ACID-BASED THERAPEUTICS

PEPTIDES AND NANOPARTICLES FOR INTRACELLULAR DELIVERY OF GENOME-EDITING MOLECULES

COMPOSITIONS AND METHODS FOR EPIGENOME EDITING

GUIDE NUCLEIC ACID IDENTIFICATION AND METHODS OF USE

METHODS AND COMPOSITIONS FOR TREATING CANCER

METHOD AND COMPOSITION FOR GENERATING BASAL FOREBRAIN CHOLINERGIC NEURONS (BFCNS)

VIRUS-FREE CRISPR CAR NATURAL KILLER CELLS

METHOD FOR INDUCING A TOLEROGENIC IMMUNE RESPONSE

METHODS AND COMPOSITIONS RELATED TO EPIGENETIC EDITING BY A METHLYLATION-DEPENDENT CAS9

RNA AND DNA ANALYSIS USING ENGINEERED SURFACES

CRISPR ENZYMES AND SYSTEMS

CRISPR ENZYMES AND SYSTEMS

METHODS AND REAGENTS FOR ENRICHMENT OF NUCLEIC ACID MATERIAL FOR SEQUENCING APPLICATIONS AND OTHER NUCLEIC ACID MATERIAL INTERROGATIONS

CRISPR-CAS13 SYSTEM AND USE THEREOF

DELIVERY, ENGINEERING AND OPTIMIZATION OF SYSTEMS, METHODS AND COMPOSITIONS FOR SEQUENCE MANIPULATION AND THERAPEUTIC APPLICATIONS

SYSTEMS AND METHODS FOR THE TREATMENT OF HEMOGLOBINOPATHIES

CRISPR-CAS COMPONENT SYSTEMS, METHODS AND COMPOSITIONS FOR SEQUENCE MANIPULATION

ENGINEERING AND OPTIMIZATION OF SYSTEMS, METHODS AND COMPOSITIONS FOR SEQUENCE MANIPULATION WITH FUNCTIONAL DOMAINS

TAT-INDUCED CRISPR/ENDONUCLEASE-BASED GENE EDITING

METHOD TO ANALYZE AND OPTIMIZE GENE EDITING MODULES AND DELIVERY APPROACHES

DNA MODIFYING ENZYMES AND ACTIVE FRAGMENTS AND VARIANTS THEREOF AND METHODS OF USE

ENGINEERING OF SYSTEMS, METHODS AND OPTIMIZED GUIDE COMPOSITIONS FOR SEQUENCE MANIPULATION

Compositions and Methods for Immunotherapy

SEQUENCE SPECIFIC ANTIMICROBIALS

PHARMACEUTICAL COMPOSITION FOR TOPICAL WOUND TREATMENT

Dual Cut Retron Editors for Genomic Insertions and Deletions