108982 ⎘
Enzymes; Proenzymes; Compositions thereof ; Processes for preparing, activating, inhibiting, separating or purifying enzymes; Hydrolases (3) acting on peptide bonds (3.4); Proteinases, e.g. Endopeptidases (3.4.21-3.4.25) derived from animal tissue from mammals
Sub-classes:GENE THERAPY SYSTEMS AND RELATED METHODS FOR TREATMENT OF HEARING LOSS
#2FAST ACTING SNARE-CLEAVING ENZYMES
#3MODIFIED ANGIOTENSIN-CONVERTING ENZYME 2 (ACE2) AND USE THEREOF
#4TASPASE1 INHIBITORS AND USES THEREOF
#5OVEREXPRESSION OF IMMUNOPROTEASOME IN HOST CELLS FOR GENERATING ANTIGEN-PRESENTING CELLS
#6METHODS AND COMPOSITIONS COMPRISING TAU OLIGOMERS
#7GENE THERAPY SYSTEMS AND RELATED METHODS FOR TREATMENT OF HEARING LOSS
#8Detection, identification, and purification of degradative and non-degradative enzymes in biological samples
#9Structure-based peptide inhibitors that target the Tau VQIINK fibrillization segment
#10Bone delivery conjugates and method of using same to target proteins to bone
#11POLYMER-BASED MATERIAL HAVING COVALENTLY BONDED ENZYMATICALLY DEGRADABLE PEPTIDE SEQUENCES
#12Targeting proteins for degradation
#13ANTI-HLA ASSAY AND METHODS
#14Three-dimensional fibroblast aggregate and in vitro 3D skin dermis model comprising same
#15TARGETED XTEN CONJUGATE COMPOSITIONS AND METHODS OF MAKING SAME
#16Peptides
#17Compositions and methods for identifying protease inhibitors
#18Methods and compositions comprising tau oligomers
#19Method for assaying a protease
#20Granzyme B protease variants
#21Modified MT-SP1 proteases that inhibit complement activation
#22Compositions having antiangiogenic activity and uses thereof
#23NT5 and NT6 alternative transcripts of the KLK8 gene encoding kallikrein 8
#24Proteasome inhibitors and uses thereof
#25USP2a peptides and antibodies
#26von Willebrand Factor (vWF) - Cleaving Protease
#27EPITOPE TESTING USING SOLUBLE HLA
#28ANTI-HLA ASSAY AND METHODS
#29COMPARATIVE LIGAND MAPPING FROM MHC CLASS I POSITIVE CELLS
#30COMPARATIVE LIGAND MAPPING FROM MHC POSITIVE CELLS
#31Method for the in vitro diagnosis of bronchopulmonary carcinoma by detection of major alternative transcripts of the KLK8 gene encoding kallikrein 8 and use thereof for prognosticating survival
#32Modified proteases that inhibit complement activation
#33Compositions having antiangiogenic activity and uses thereof
#34PROTEASOME INHIBITORS AND USES THEREOF
#35TAU PROTEASE COMPOSITIONS AND METHODS
#36Compositions and Methods for Identifying Substrate Specificity of Inhibitors of Gamma Secretase
#37Polynucleotides and Polypeptides Encoding Receptors
#38Nel-related type 1 polypeptide
#39Single domain antibodies capable of modulating BACE activity
#40EPITOPE TESTING USING SOLUBLE HLA
#41BACE455, AN ALTERNATIVE SPLICE VARIANT OF THE HUMAN BETA-SECRETASE
#42Method for the in vitro diagnosis of bronchopulmonary carcinoma by detection of major alternative transcripts of the KLK8 gene encoding kallikrein 8 and use thereof for prognosticating survival
#43Bone delivery conjugates and method of using same to target proteins to bone
#44MOLECULES AND METHODS FOR MODULATING PROPROTEIN CONVERTASE SUBTILISIN/KEXIN TYPE 9 (PCSK9)
#45Bone delivery conjugates and method of using same to target proteins to bone
#46Refolded recombinant β-secretase crystals and methods for preparing and using the same
#47CLONING AND CHARACTERIZATION OF 5' FLANKING REGIONS OF A HUMAN AGGRECANASE-1 GENE
#48Method for identifying smoker or ex-smoker at risk of chronic obstructive pulmonary disease
#49Human skeletal muscle-specific ubiquitin-conjugating enzyme
#50TRANSGENIC NON-HUMAN ANIMAL
#51Compositions Having Antiangiogenic Activity and Uses Thereof
#52Crystallization and Structure Determination of Glycosylated Human Beta Secretase, an Enzyme Implicated in Alzheimer's Disease
#53PURIFICATION AND CHARACTERIZATION OF SOLUBLE MHC PROTEINS
#54Nel-related protein type 1 antibody
#55Method of inhibiting human Trabid
#56TRUNCATED MEMAPSIN 2 COMPOSITIONS AND TREATMENTS
#57Novel Egg Receptors for Sperm Proteins
#58Polynucleotides and Polypeptides Encoding Receptors
#59AGENTS FOR PRE-SYMPTOMATIC DETECTION AND THERAPEUTIC TARGETING OF ALZHEIMER'S DISEASE AND DOWN SYNDROME IN HUMANS
#60Methods for removing anti-MHC antibodies from a sample
#61Tomoregulin-2-antibody compositions and methods for the diagnosis and treatment of Alzheimer's disease
#62Crystallization and structure determination of glycosylated human beta secretase, an enzyme implicated in alzheimer's disease
#63Method for refolding enzymes
#64Compositions and Methods for Identifying Substrate Specificity of Inhibitors of Gamma Secretase
#65PROCESS FOR THE DETERMINATION OF THE PRIMARY STRUCTURE OF THE MESSENGER RNA CODING FOR THE HUMAN RECOMBINANT ENDOOLIGOPEPTIDASE A (HEOPA) [AF217798]
#66COMPOSITIONS AND METHODS INVOLVING GENE THERAPY AND PROTEASOME MODULATION
#67Novel BACE proteins, nucleic acid molecules therefor, novel crystal structure of novel BACE proteins, and methods for making and using
#68Von Willebrand factor (vWF)-cleaving protease
#69New Method 706
#70Crystallization and structure determination of beta secretase and/or beta secretase-like proteins
#71Pharmaceutical compositions for treating arthritis and inflammatory disease
#72Transgenic Animal Models for Neurodevelopmental Disorders
#73Methods of screening for inhibitors of antiplasmin cleaving enzyme
#74Catalytically active recombinant memapsin and methods of use thereof
#75GENE 4
#76PHARMACEUTICAL COMPOSITIONS FOR TREATING ARTHRITIS AND INFLAMMATORY DISEASE
#77Polynucleotides and Polypeptides Encoding Receptors
#78Human gene
#79Inhibitors of Memapsin 2 and use thereof
#80Protein conjugates with a water-soluble biocompatible, biodegradable polymer
#81Novel human proteases and polynucleotides encoding the same
#82Cloning And Characterization Of 5'Flanking Regions Of A Human Aggrecanase-1 Gene
#83Modulation of Abeta levels by beta-secretase BACE2
#8432263, a novel human biotin enzyme and uses thereof
#85Methods for modulating proteins not previously known as proteases
#86Aggrecanase structure
#87Truncated aggrecanase molecules
#88Native TRRE: protein implicated in TNF receptor shedding for treating arthritis and inflammation
#89Antibody to BACE455, an alternative splice variant of the human beta-secretase
#90Aggrecanase molecules
#91Human skeletal muscle-specific ubiquitin-conjugating enzyme
#92Aggrecanase structure
#93Methods of identifying compounds that inhibit Notch cleavage
#94Method for making β-secretase co-crystals complexed with a ligand
#95Marburg I mutant of factor VII activating protease (FSAP) as risk factor for arterial thrombosis and methods of detecting FSAP and FSAP mutations
#96Comparative ligand mapping from MHC positive cells
#97Modified proteases that inhibit complement activation
#98TRUNCATED MEMAPSIN 2 COMPOSITIONS AND TREATMENTS
#99Novel ubp8rp polypeptides and their use in the treatment of psoriasis
#100Nucleic acid expressed in the hypothalamus or muscle tissue in obese animals
#101Regulators of type-1 tumor necrosis factor receptor and other cytokine receptor shedding
#102Process for the determination of the primary structure of the messenger rna coding for the human recombinant endooligopeptidase a (heopa)(af217798)...
#103HUMAN CCV POLYPEPTIDES
#104Universal procedure for refolding recombinant proteins
#105Aortic carboxypeptidase-like polypeptide
#106Purification and characterization of soluble human HLA proteins
#107Rat and mouse members of the CRISP family of genes
#108Novel tumor antigen useful in diagnosis and therapy of prostate and colon cancer
#109Truncated aggrecanase molecules
#110Interleukin 1beta protease and interleukin 1beta protease inhibitors
#111Novel beta-secretase and modulation of beta-secretase activity
#112Transgenic mice containing deubiquitinated enzyme gene disruptions
#113Method for crystallizing human beta secretase in complex with an inhibitor
#114Composition and methods relating to SENP1—a sentrin-specific protease
#115Human gene
#116Aggrecanase
#117von Willebrand factor (vWF)—cleaving protease
#118Lactacystin analogs
#119Epitope testing using soluble HLA
#120Human hydrolase family members and uses thereof
#121Administration of neutral endopeptidase to treat inflammatory bowel disease
#122Constructs for homogenously processed preparations of beta site APP-cleaving enzyme
#123Novel promoter
#124Bone delivery conjugates and method of using same to target proteins to bone
#125Novel proteases
#126Proteases and protease inhibitors
#127Isolated human protease proteins, nucleic acid molecules encoding human protease proteins, and uses thereof
#128Mammalian proteases; related reagents
#129Proteases
#130Proteases
#131Noved human proteases and polynucleotides encoding the same
#132Treatment of inflammatory disease by cleaving TNF receptors
#133Polynucleotides and polypeptides encoding receptors
#134Novel human protease and polynucleotides encoding the same
#135Tissue plasminogen activator-like protease
#136Aggrecanase-1 and -2 peptide substrates and methods
#137Novel human proteases and polynucleotides encoding the same
#138Treating arthritis by cleaving TNF receptors
#139Methods for diagnosing and treating autoimmune disease
#140Protein modification and maintenance molecules
#141Secreted proteins
#142Human proteins
#143Proteases
#144Protein modification and maintenance molecules
#145Human aggrecanase and nucleic acid compositions encoding the same
#146Identification of differentially methylated and mutated nucleic acids
#147Novel human proteases and polynucleotides encoding the same
#148Pharmaceutical compositions for treating arthritis and inflammatory disease
#149Constructs for homogenously processed preparations of beta site APP-cleaving enzyme
#150Secreted proteins
#151Nucleic acid expressed in the hypothalamus or muscle tissue in obese animals
#152Agents for pre-symptomatic detection and therapeutic targeting of alzheimer's disease and down syndrome in humans
#153Dominant negative variants of methionine aminopeptidase 2 (MetAP2) and clinical uses thereof
#154Protein modification and maintenance molecules
#155Methods of attaching soluble HLA to solid supports
#156Comparative ligand mapping from MHC class 1 positive cells
#157System and method for creating crystals of human acetylcholinesterase with open active sites