108986 ⎘
Enzymes; Proenzymes; Compositions thereof ; Processes for preparing, activating, inhibiting, separating or purifying enzymes; Hydrolases (3) acting on peptide bonds (3.4); Proteinases, e.g. Endopeptidases (3.4.21-3.4.25) derived from animal tissue from mammals Metalloendopeptidases (3.4.24)
3D-PRINTED SKIN MODEL USING PERSONALIZED DECELLULARIZED ECM
#2HUMANIZED LIGHT CHAIN MICE
#3DUAL-SPECIFIC BINDING MOLECULE USEFUL FOR ISOLATING SPECIFIC BLOOD CELLS
#4THERAPEUTIC MACROPHAGES
#5METHODS OF PURIFYING RECOMBINANT ADAMTS13 AND OTHER PROTEINS AND COMPOSITIONS THEREOF
#6CELL-FREE CLOSTRIDIAL NEUROTOXIN ASSAYS
#7Thrombolytic Protease Resistant ADAMTS13 Mutants
#8METHOD OF CULTURING MESENCHYMAL STEM CELLS
#9METHODS AND COMPOSITIONS RELATED TO ENGINEERED THERMOGENIC MICROVASCULARFRAGMENTS (MVFS)
#10METHODS FOR PRODUCING ANTIGEN-BINDING PROTEINS AGAINST FOREIGN ANTIGENS
#11METHODS AND COMPOSITIONS FOR INHIBITING ADAM10 BIOLOGICAL ACTIVITIES
#12METHOD FOR INCREASING BOTULINUM TOXIN PRODUCTIVITY
#13COMPOSITION COMPRISING COLLAGENASE, CALCIUM, HISTIDINE, AND GLYCINE, AND METHOD FOR STABILIZING COLLAGENASE
#14METHODS AND COMPOSITIONS FOR INHIBITING ADAM9 BIOLOGICAL ACTIVITIES
#15CULTURE OF TUMOR INFILTRATING LYMPHOCYTES FROM TUMOR DIGEST
#16BACTERIOLYSIS METHOD, BACTERIOLYSIS AID, AND METHOD FOR DETERMINING THE PRESENCE OR ABSENCE OF BACTERIA
#17COMPOSITION COMPRISING COLLAGENASE, CALCIUM, HISTIDINE, AND GLYCINE, AND METHOD FOR STABILIZING COLLAGENASE
#18COMPOSITIONS AND METHODS FOR ALTERING AMYLOID PRECURSOR PROTEIN (APP) PROCESSING
#19CATALYTICALLY INACTIVE CLOSTRIDIAL NEUROTOXINS FOR THE TREATMENT OF PAIN & INFLAMMATORY DISORDERS
#20RIGID SURFACE TREATMENT AGENT
#21MODIFIED RECOMBINANT COLLAGENASE, COMPOSITIONS COMPRISING THE SAME AND USES THEREOF IN DENTAL RELATED PROCEDURES
#22TOOL AND METHOD FOR DISAGGREGATION OF POLYQ STRETCH-CONTAINING PROTEINS
#23ADAM6 MICE
#24PROCASPASE-CLEAVING PROTEASES AND USES THEREOF
#25PEPTIDES FOR THE TREATMENT OF CANCER AND/OR METASTASIS
#26COMBINATION THERAPY USING CLOSTRIDIAL TOXIN DERIVATIVE AND AT LEAST ONE CHEMICAL DEPOLARIZING AGENT
#27Clostridial Neurotoxins Comprising an Exogenous Activation Loop
#28FEED COMPOSITION SUPPLEMENTED WITH A PROTEASE COMBINATION
#29METHOD FOR SEPARATING SPERMATOGONIAL STEM CELLS (SSCs) FROM FROZEN TESTICULAR TISSUE
#30Compositions and Methods for Treating Celiac Sprue Disease
#31IMMUNOGENIC PROTEIN HYDROLYSATE WITH REDUCED ALLERGENICITY
#32ADAMTS13 VARIANT
#33LEATHER IMPROVING AGENT
#34AUTOMATIC DISHWASHING DETERGENT COMPOSITIONS
#35TRUNCATED MODIFIED RECOMBINANT ADAMTS13 AND USES THEREOF
#36COMPOSITION FOR TREATING OR PREVENTING MYOPATHY, OBESITY OR DIABETES
#37MUTANT PROTEASE AND USE THEREOF
#38NATURAL KILLER CELLS WITH ENHANCED ACTIVITY
#39Methods for Lysis of Cells Within a Sample
#40HUMANIZED LIGHT CHAIN MICE
#41A DISINTEGRIN AND METALLOPROTEINASE WITH A THROMBOSPONDIN TYPE I MOTIF, MEMBER 13 (ADAMTS-13) MUTANTS, COMPOSITIONS AND THERAPEUTIC METHODS THEREOF
#42COMPOSITION COMPRISING RECOMBINANT CLOSTRIDIUM NEUROTOXIN
#43METHODS OF PURIFYING RECOMBINANT ADAMTS13 AND OTHER PROTEINS AND COMPOSITIONS THEREOF
#44ADAMTS13 PROTEIN VARIANTS AND USES THEREOF
#45ADAMTS13 VARIANT, COMPOSITIONS, AND USES THEREOF
#46Methods and compositions for inhibiting ADAM10 biological activities
#47COMPOSITIONS AND METHODS OF ADAMTS13 CHIMERIC AUTOANTIBODY RECEPTOR CELLS
#48DERMAL FILLER
#49BLENDS CONTAINING PROTEASES
#50BOTULINUM NEUROTOXINS PRODUCTION METHODS
#51CHARACTERIZING MODULATORS OF ADAMTS-7 AND ADAMTS-12
#52HUMANIZED UNIVERSAL LIGHT CHAIN MICE
#53IMMUNOGENIC PEPTIDE FRAGMENTS OF METALLOPROTEASE ADAMTS-7 AND USES THEREOF IN ANTI-ATHEROSCLEROSIS AND RELATED DISEASES
#54DERMAL FILLER
#55TARGETED DELIVERY OF TUMOR MATRIX MODIFYING ENZYMES
#56RED BLOOD CELLS EXPRESSING VON WILLEBRAND FACTOR PROTEASE AND METHODS OF USE THEREOF
#57METHODS AND COMPOSITIONS FOR INHIBITING ADAM8 BIOLOGICAL ACTIVITIES
#58METHODS FOR PRODUCING ANTIGEN-BINDING PROTEINS AGAINST FOREIGN ANTIGENS
#59COMBINATION THERAPY USING CLOSTRIDIAL TOXIN DERIVATIVE AND AT LEAST ONE CHEMICAL DEPOLARIZING AGENT
#60Subcutaneous administration of ADAMTS13
#61Feed composition supplemented with a protease combination
#62IMPROVED DELIVERY OF LARGE AGENTS
#63ADAMTS13-CONTAINING COMPOSITIONS HAVING THROMBOLYTIC ACTIVITY
#64HUMANIZED RODENTS THAT EXPRESS HEAVY CHAIN CONTAINING VL DOMAINS
#65Compositions and Methods for Treating Celiac Sprue Disease
#66ANIMAL PRODUCT FREE SYSTEM AND PROCESS FOR PURIFYING A BOTULINUM TOXIN
#67ANIMAL PRODUCT FREE SYSTEM AND PROCESS FOR PURIFYING A BOTULINUM TOXIN
#68MITOCHONDRIAL PROTEASE OMA1 AS A MARKER FOR BREAST CANCER
#69Production method for protease of M23A subfamily
#70VARIANTS OF TACE PRO-DOMAIN AS TNF-A INHIBITOR AND THEIR MEDICAL USE
#71Method of producing recombinant high molecular weight vWF in cell culture
#72BOTULINUM NEUROTOXINS PRODUCTION METHODS
#73ADAM6 mice
#74ADAM6 mice
#75ANIMAL PRODUCT FREE SYSTEM AND PROCESS FOR PURIFYING A BOTULINUM TOXIN
#76Bicyclic peptide ligands and uses thereof
#77ANIMAL PRODUCT FREE SYSTEM AND PROCESS FOR PURIFYING A BOTULINUM TOXIN
#78Methods for Lysis of Cells Within a Sample
#79ADAMTS13 protein cell culture supernatant
#80Pappalysin regulator
#81Humanized light chain mice
#82Humanized light chain mice
#83Inhibition of vascular matrix metalloproteinase-9 to treat ischemic injury
#84Transgenic Animals
#85Compositions and methods for treating celiac sprue disease
#86Subcutaneous administration of ADAMTS13
#87Methods and compositions for inhibiting ADAM 9 biological activities
#88Mitochondrial protease OMA1 as a marker for breast cancer
#89METHODS AND COMPOSITIONS FOR INHIBITING ADAM10 BIOLOGICAL ACTIVITIES
#90Variants of TACE pro-domain as TNF-A inhibitor and their medical use
#91Fusion proteins of collagen-binding domain and parathyroid hormone
#92Compositions and Methods for Altering Amyloid Precursor Protein (APP) Processing
#93Composition comprising recombinant clostridium neurotoxin
#94Phosphate-free automatic dishwashing detergent compositions having a protease and a complexing agent
#95ADAMTS13-containing compositions having thrombolytic activity
#96Method of producing a polypeptide or virus of interest in a continuous cell culture
#97Fusion proteins of collagen-binding domain and parathyroid hormone
#98Humanized universal light chain mice
#99VARIANTS OF TISSUE INHIBITOR OF METALLOPROTEINASE TYPE THREE (TIMP-3), COMPOSITIONS AND METHODS
#100Method of producing recombinant high molecular weight vWF in cell culture
#101Cell culture methods for expressing ADAMTS protein
#102OMA1 activity assay
#103ADAM6 mice
#104ADAM6 mice
#105ADAM6 mice
#106ADAM6 mice
#107Bicyclic peptide ligands and uses thereof
#108COMPOSITION FOR RAPIDLY SEPARATING ADIPOSE TISSUE-DERIVED STROMAL CELLS
#109Transgenic Animals
#110Botulinum neurotoxin compositions
#111Manufacture of di-chain recombinant neurotoxins using Lys-C and a hydrophobic surface
#112Method for treating vascular stenosis or occlusive disease due to thrombi by administering a saxatilin-fc fusion protein
#113Method of producing a polypeptide or virus of interest in a continuous cell culture
#114Method of producing recombinant high molecular weight vWF in cell culture
#115Multimodal antimicrobial therapy
#116ANIMAL PRODUCT FREE SYSTEM AND PROCESS FOR PURIFYING A BOTULINUM TOXIN
#117METHODS FOR BREAKING IMMUNOLOGICAL TOLERANCE USING MULTIPLE GUIDE RNAS
#118Humanized light chain mice
#119Variants of TACE pro-domain as TNF-A inhibitor and their medical use
#120Subcutaneous administration of ADAMTS13
#121Dermal filler
#122Method for inhibiting ADAM proteases with cyclic peptides
#123Fusion proteins of collagen-binding domain and parathyroid hormone
#124Cell culture methods for expressing ADAMTS13 protein
#125Method of producing recombinant high molecular weight vWF in cell culture
#126Transgenic Animals
#127CELL CULTURE PROCESSES
#128Detection and removal of misfolded proteins/peptides
#129Compositions and methods for treating celiac sprue disease
#130Cyclic peptides as ADAM protease inhibitors
#131Pappalysin Regulator
#132Variants of tissue inhibitor of metalloproteinase type three (TIMP-3), compositions and methods
#133Antibacterial phage, phage peptides and methods of use thereof
#134Cell culture medium for ADAMTS protein expression
#135Fusion proteins of collagen-binding domain and parathyroid hormone
#136ADAM6 mice
#137ADAM6 mice
#138FUNCTION AND REGULATION OF ADAMTS-1
#139Multimodal antimicrobial therapy
#140TIKI inhibitors
#141Pregnancy-associated plasma protein-A2 (PAPP-A2) polypeptides
#142Variants of TACE pro-domain as TNF-A inhibitor and their medical use
#143Methods of purifying recombinant ADAMTS13 and other proteins and compositions thereof
#144METHODS FOR MODIFICATION OF TISSUES
#145METHOD OF PRODUCING RECOMBINANT HIGH MOLECULAR WEIGHT vWF IN CELL CULTURE
#146Peptide increasing fusiogenic capacity of a gamete
#147ADAMTS-13 mutant
#148Gain-of-function ADAMTS13 variants resistant to auto antibody inhibition and methods of use thereof
#149Method of producing recombinant high molecular weight vWF in cell culture
#150Composition exhibiting a von Willebrand factor (vWF) protease activity comprising a polypeptide chain with the amino acid sequence AAGGILHLELLV
#151Cell culture medium for ADAMTS protein expression
#152FUNCTION AND REGULATION OF ADAMTS-1
#153Subcutaneous administration of ADAMTS13
#154Suppression of prostate cancer using a targeted clostridial neurotoxin
#155ADAM6 mice
#156METHOD FOR PREPARING MICROVESICULAR ADAM15
#157ADAMTS-13 mutant
#158Animal product free system and process for purifying a botulinum toxin
#159Compositions having antiangiogenic activity and uses thereof
#160Detection and removal of misfolded proteins/peptides
#161Method of producing a polypeptide or virus of interest in a continuous cell culture
#162Humanized light chain mice
#163Use of ide as a biomarker for a scalp condition
#164Fusion proteins of collagen-binding domain and parathyroid hormone
#165Composition for dissolving thrombi, and a pharmaceutical composition for treating stenotic or occlusive vascular diseases which comprises the same
#166Humanized universal light chain mice
#167Humanized light chain mice
#168ADAMTS13-containing compositions having thrombolytic activity
#169Pregnancy-associated plasma protein-A2 (PAPP-A2) polynucleotides
#170Methods for increasing recovery of an ADAMTS activity from a cell culture supernatant
#171PRODOMAIN MODULATORS OF ADAM 10
#172MODIFIED ADAM DISINTEGRIN DOMAIN POLYPEPTIDES AND USES THEREOF
#173von Willebrand Factor (vWF) - Cleaving Protease
#174ADAM6 mice
#175Compositions having antiangiogenic activity and uses thereof
#176Bioactive Macromers and Hydrogels and Methods for Producing Same
#177Polypeptides for the in vitro assessment of the sensitising potential of a test compound
#178Animal product free system and process for purifying a botulinum toxin
#179Fusion proteins
#180ADAMTS-13 mutant
#181METHODS AND COMPOSITIONS FOR PROMOTING WOUND HEALING
#182Antibacterial phage, phage peptides and methods of use thereof
#183Method of producing recombinant high molecular weight vWF in cell culture
#184Method of producing recombinant ADAMTS13 in cell culture
#185PRODOMAIN MODULATORS OF ADAM 10
#186Metallopeptide catalysts
#187Screening and treatment methods using IGS5 enzymes of the metalloprotease family
#188ANTIBODIES AND METHODS OF DIAGNOSING DISEASES
#189Non-cytotoxic protein conjugates
#190SUPPRESSION OF NEUROENDOCRINE DISEASES
#191Polypeptides that bind to and inhibit secretion from growth hormone secreting cells
#192Polynucleotides and Polypeptides Encoding Receptors
#193METHOD OF DIAGNOSING A CLINICAL CONDITION BY DETECTION OF A PAPP-A/proMBP COMPLEX
#194Methods for expressing ADAMTS proteins in cell culture medium supplemented with zinc
#195Method of producing a polypeptide or virus of interest in a continuous cell culture
#196Methods of purifying recombinant ADAMTS13 and other proteins and compositions thereof
#197FUNCTION AND REGULATION OF ADAMTS-1
#198Therapeutic agents for inducing platelet fragmentation and treating thromboembolic disorders
#199DNA fragment and use thereof
#200Non-human gene-disrupted animal with disrupted ADAM11 gene
#201Selective exosite inhibition of PAPP-A activity against IGFBP-4
#202PROTEASE INHIBITION
#203Fusion proteins
#204PLASMID CONTAINING A SEQUENCE ENCODING A DISINTEGRIN DOMAIN OF METARGIDIN (RDD)
#205Use of a chromatography substrate for reducing the amount of ADAMTS13 in a solution derived from plasma
#206Modified tumor necrosis factor-alpha converting enzyme and methods of use thereof
#207Method of producing microbial transglutaminase
#208Compositions Having Antiangiogenic Activity and Uses Thereof
#209Novel 27875, 22025, 27420, 17906, 16319, 55092 and 10218 molecules and uses therefor
#210Fusion proteins of collagen-binding domain and parathyroid hormone
#211Prodomain modulators of ADAM 10
#212INSULIN-DEGRADING ENZYME MUTANTS AND METHODS OF USE
#213genes and proteins and variants, and therapeutic compositions and methods of utilizing the same
#214Inhibition of TACE or amphiregulin for the modulation of EGF receptor signal transactivation
#215Media for clostridium bacterium and processes for obtaining a clostridial toxin
#216genes and proteins and variants, and therapeutic compositions and methods of utilizing the same
#217TARGETING TNF-alpha CONVERTING ENZYME(TACE)- DEPENDENT GROWTH FACTOR SHEDDING IN CANCER THERAPY
#218Treating diseases mediated by metalloprotease-shed proteins
#219Inhibition of tumor growth and invasion by anti matrix metalloproteinase DNAzymes
#220Modified tumor necrosis factor-alpha converting enzyme and methods of use thereof
#221Pharmaceutical Composition For Treating Vascular-Related Diseases Comprising Peptide
#222Polynucleotides and Polypeptides Encoding Receptors
#223BIOLOGICAL ENTITIES AND THE USE THEREOF
#224BIOLOGICAL ENTITIES AND THE USE THEREOF
#225Composition exhibiting a von willebrand factor (vWF) protease activity comprising a polypeptide chain with the amino acid sequence AAGGILHLELLV
#226Methods of Screening for Atherosclerosis
#227Cell culture processes
#228Non-cytotoxic protein conjugates
#229Dermal filler
#230CHROMATOGRAPHIC METHOD AND SYSTEM FOR PURIFYING A BOTULINUM TOXIN
#231CHROMATOGRAPHIC METHOD AND SYSTEM FOR PURIFYING A BOTULINUM TOXIN
#232Methods and compositions for promoting wound healing
#233SVPH1-26 DNA and polypeptides
#234Composition exhibiting a von Willebrand Factor (vWF) protease activity comprising a polypeptide chain with the amino acid sequence AAGGILHLELLV
#235Novel Integrin Ligand ITGL-TSP
#236Antibody against a human ADAM protease
#237METH1 and METH2 Polynucleotides and Polypeptides
#238Pharmaceutical Composition Containing Meltrin Antagonist
#239Fusion Proteins Having a Modulated Half-Life in Plasma
#240Von Willebrand factor (vWF)-cleaving protease
#241Mam Domain Containing Protein
#242CATALYTIC DOMAIN OF ADAM33 AND METHODS OF USE THEREOF
#243Non-cytotoxic protein conjugates
#244Composition exhibiting a von Willebrand Factor (vWF) protease activity with the amino acid sequence AAGGILHLELLV
#245Antibodies that bind TNF-α converting enzyme
#246Pharmaceutical compositions for treating arthritis and inflammatory disease
#247Novel 27875, 22025, 27420, 17906, 16319, 55092 and 10218 molecules and uses therefor
#248Novel 27875, 22025, 27420, 17906, 16319, 55092 and 10218 molecules and uses therefor
#249PHARMACEUTICAL COMPOSITIONS FOR TREATING ARTHRITIS AND INFLAMMATORY DISEASE
#250Prodomain modulators of ADAM 10
#251Polypeptides for bone mineralization
#252Novel Human Enzymes of the Metalloprotease Family
#253Methods for the treatment of thrombosis
#254Polynucleotides and Polypeptides Encoding Receptors
#255Galectin 11
#256Inhibitors of L1 and ADAM10 for the treatment of carcinomas
#257Method for the Detection of Autoantibodies Against Specific Peptides and Its Use in Diagnosis and Treatment of Pregnancy-Loss or Infertility
#258ASSAYS AND PEPTIDE SUBSTRATE FOR DETERMINING AGGRECAN DEGRADING METALLO PROTEASE ACTIVITY
#259Novel Metalloproteinases
#260Screening and treatment methods using IGS5 enzymes of the metalloprotease family
#261Transgenic mice containing TRP gene disruptions
#262Biological agent that causes IL-6 receptor release
#263Antibody to human enzymes of the metalloprotease family
#264Methods for identifying modified tumor necrosis factor-alpha converting enzyme inhibitors
#265Native TRRE: protein implicated in TNF receptor shedding for treating arthritis and inflammation
#266Pregnancy-associated plasma protein-A2 (PAPP-A2)
#267Nucleic acids encoding human TNF-α convertase
#268Media for bacterium
#269Metalloprotease-disintegrin ADAM23 (SVPH3-17)
#270Peptide increasing fusiogenic capacity of a gamete
#271Substrate polyeptides for von Willebrand factor cleaving protease ADAMTS-13
#272Function and regulation of ADAMTS-1
#273Catalytic domain of ADAM33 and methods of use thereof
#274Novel Integrin Ligand ITGL-TSP
#275Novel Integrin Ligand ITGL-TSP
#276ADAMTS13-containing compositions having thrombolytic activity
#277HUMAN CCV POLYPEPTIDES
#278TNF-α converting enzyme inhibitory agents and method of using same
#279Human disintegrin protein
#280Larynx carcinoma-associated protein larcap-1
#281Metalloprotease proteins
#282Antibody against von Willebrand factor cleaving enzyme and assay system using the same
#283Meltrins
#284Sequences encoding genes and proteins
#285Inhibition of TACE or amphiregulin for the modulation of EGF receptor signal transactivation
#286Construct comprising recognition domain of antibody against von Willebrand factor-specific cleaving enzyme
#287ADAMTS13 genes and proteins and variants and therapeutic compositions and methods utilizing the same
#288Peptide substrates of a proteolytic ADAM33 polypeptide and assays using the same
#289Chromatographic method and system for purifying a botulinum toxin
#290Novel protease gene
#291Modified ADAMTS4 molecules and method of use thereof
#292Novel protein and DNA thereof
#293Novel genes encoding proteins having prognostic, diagnostic, preventive, therapeutic and other uses
#294Human enzymes of the metalloprotease family
#295Integrin antagonists
#296Insulin-like growth factor binding protein-4 protease
#297Metalloprotease highly expressed in the testis, MMP-29
#298Aggrecanase
#299von Willebrand factor (vWF)—cleaving protease
#30081588 methods and compositions of human proteins and uses thereof