108997 ⎘
Enzymes; Proenzymes; Compositions thereof ; Processes for preparing, activating, inhibiting, separating or purifying enzymes Stabilising an enzyme by forming an adduct or a composition; Forming enzyme conjugates
Purification of polymerase complexes
#302Compositions and methods for treatment of homocystinuria
#303GENERATION AND CORRECTION OF A HUMANIZED MOUSE MODEL WITH A DELETION OF DYSTROPHIN EXON 44
#304Liquid Enzyme Preparation and Preparation Method Thereof
#305Purification of polymerase complexes
#306Methods of preparing a solid composition containing proteases
#307PEPTIDE ANTIBIOTIC COMPLEXES AND METHODS OF USE THEREOF
#308Switchable CAS9 nucleases and uses thereof
#309CRISPR CPF1 direct repeat variants
#310Long-acting coagulation factors and methods of producing same
#311Glycerol-free formulations for reverse transcriptases
#312Engineered heme-binding compositions and uses thereof
#313Methods for treating pseudoxanthoma elasticum (PXE)
#314Using RNA-guided FokI nucleases (RFNs) to increase specificity for RNA-guided genome editing
#315INNOVATIVE DISCOVERY OF THERAPEUTIC, DIAGNOSTIC, AND ANTIBODY COMPOSITIONS RELATED TO PROTEIN FRAGMENTS OF ALANYL TRNA SYNTHETASES
#316Substituted 6,11-dihydro-5H-benzo[B]carbazoles as inhibitors of ALK and SRPK
#317Conjugates of biologically active molecules to functionalized polymers
#318Site-specific polyethylene glycolylated (pegylated) asparaginase, preparation method therefor and use thereof
#319Methods and compositions for the treatment of cellulosic biomass and products produced thereby
#320Inhibitors of kidney-type glutaminase, GLS-1
#321Expansin-agarase enzyme complex and method for degrading agar by using same
#322High concentration alpha-glucosidase compositions for the treatment of Pompe disease
#323METHODS AND COMPOSITIONS FOR SINGLE CHAIN VARIABLE REGION ENOX2 ANTIBODIES FOR CANCER DETECTION AND DIAGNOSIS
#324Compositions for increasing polypeptide stability and activity, and related methods
#325Chromogenic peroxidase substrates
#326SYNTHETIC BRASSICA-DERIVED CHLOROPLAST TRANSIT PEPTIDES
#327PEPTIDE-MEDIATED DELIVERY OF RNA-GUIDED ENDONUCLEASE INTO CELLS
#328Self-assembling protein scaffolds and methods
#329Histidyl-tRNA synthetase-Fc conjugates
#330CRISPR-BASED GENOME MODIFICATION AND REGULATION
#331METHOD FOR MONOMERIZING MATRIX METALLOPROTEINASE 7 (MMP-7) AGGREGATE
#332INNOVATIVE DISCOVERY OF THERAPEUTIC, DIAGNOSTIC, AND ANTIBODY COMPOSITIONS RELATED TO PROTEIN FRAGMENTS OF METHIONYL-TRNA SYNTHETASES
#333Compositions for treating pathological calcification conditions, and methods using same
#334Stabilization of glutamate dehydrogenase in an aqueous solution
#335Gold optimized CAR T-cells
#336Compositions and methods for treating cancer
#337PHARMACEUTICAL COMBINATION FOR TREATMENT OF FABRY DISEASE AND USE THEREOF
#338CONTROLLED BREAK ENZYME FORMULATIONS
#339Viscosity-reducing compounds for protein formulations
#340Coatings containing enzyme for stable self-cleaning of organic stains
#341Antigen-specific tolerance and compositions for induction of same
#342HIGH-THROUGHPUT SYNTHESIS OF BIOMOLECULE-POLYMER CONJUGATES
#343Engineered enzymes with methionine-gamma-lyase enzymes and pharmacological preparations thereof
#344Encapsulated Solid Enzyme Product
#345Using truncated guide RNAs (tru-gRNAs) to increase specificity for RNA-guided genome editing
#346Engineered nucleic-acid targeting nucleic acids
#347Immunoglobulin chimeric monomer-dimer hybrids
#348Downstream Processing of an Alkaline Phosphatase
#349Systems and methods for one-shot guide RNA (ogRNA) targeting of endogenous and source DNA
#350INNOVATIVE DISCOVERY OF THERAPEUTIC, DIAGNOSTIC, AND ANTIBODY COMPOSITIONS RELATED TO PROTEIN FRAGMENTS OF ASPARAGINYL TRNA SYNTHETASES
#351BRANCHED POLYMERS
#352Gold optimized CAR T-cells
#353Thrombin solution and methods of use thereof
#354Reagents and methods for esterification
#355COMBINATION THERAPY WITH CGRP ANTAGONISTS AND CLOSTRIDIAL DERIVATIVES
#356Methods and compositions for biopreservation
#357BIOLOGICAL FLUIDS
#358Mapping a Functional Cancer Genome Atlas of Tumor Suppressors Using AAV-CRISPR Mediated Direct In Vivo Screening
#359Oligosaccharides comprising an aminooxy group and conjugates thereof
#360Conjugates of tumor necrosis factor inhibitors to functionalized polymers
#361Aqueous solution of burlulipase comprising calciumions
#362Cas9 proteins and guiding features for DNA targeting and genome editing
#363Targeted protease compositions and uses related thereto
#364Polymer engineered regenerating bioscavengers
#365Polymer engineered regenerating bioscavengers
#366Stabilized Proteins and Method of Making the Same
#367Anti-indoleamine 2,3-dioxygenase 1 antibodies and diagnostic uses thereof
#368Polymerase-template complexes
#369RNA-guided targeting of genetic and epigenomic regulatory proteins to specific genomic loci
#370Heteroaryl compounds and uses thereof
#371Bioresponsive particles
#372Enzymatic reaction medium containing surfactant
#373Composition for polymerase reaction
#374Reprogramming urokinase into an antibody-recruiting anticancer agent
#375Mutant glucose oxidase and use thereof
#376Acinetobacter lysins
#377Complexes for gene deletion and editing
#378Blood coagulation protein conjugates
#379Gold optimized CAR T-cells
#380Compositions comprising a GH61 polypeptide having cellulolytic enhancing activity and a liquor and method of using thereof
#381Proteome Editing System
#382STABILIZATION OF ENZYMES IN COMPOSITIONS
#383Stable lignocellulolytic enzyme composition
#384Innovative discovery of therapeutic, diagnostic, and antibody compositions related to protein fragments of Histidyl-tRNA synthetases
#385Viscosity-reducing excipient compounds for protein formulations
#386Butyrylcholinesterase zwitterionic polymer conjugates
#387METHOD FOR MANUFACTURING A STABLE AQUEOUS SOLUTION OF BETA-AMYLASE, AQUEOUS SOLUTION OBTAINED AND USES THEREOF
#388Compositions for treating pathological calcification conditions, and methods using same
#389Compositions and methods relating to synthetic RNA polynucleotides created from synthetic DNA oligonucleotides
#390Methods and compositions for regulation of transgene expression
#391Processing engineered FMDV P1 polypeptide using an alternative TEV protease
#392REVERSE TRANSCRIPTASE MIXTURES WITH IMPROVED STORAGE STABILITY
#393Factor IX polypeptides and methods of use thereof
#394Factor IX polypeptides and methods of use thereof
#395Method for obtaining active insoluble xylose isomerase
#396Preparation of lipase with improved ester synthesis activity by using surfactants
#397Fusion proteins with improved properties
#398PRODUCTS AND METHODS FOR ASSESSING AND INCREASING KLOTHO PROTEIN LEVELS
#399Dried L-glutamate oxidase composition
#400CRISPR-CAS SYSTEMS FOR ALTERING EXPRESSION OF GENE PRODUCTS
#401Biofunctional materials
#402BIOFUNCTIONAL MATERIALS
#403Biofunctional materials
#404Aldehyde tags, uses thereof in site-specific protein modification
#405Dithioamine reducing agents
#406Devices for CRISPR effector system based diagnostics
#407Coatings containing polymer modified enzyme for stable self-cleaning of organic stains
#408Coatings containing polymer modified enzyme for stable self-cleaning of organic stains
#409Coatings containing polymer modified enzyme for stable self-cleaning of organic stains
#410Application of gene in improving photosynthesis of rice
#411MK2 inhibitors and uses thereof
#412Supramolecular protein assemblies with advanced functions and synthesis thereof
#413Conjugates of biologically active molecules to functionalized polymers
#414Compositions and methods for treatment of homocystinuria
#415TAL-effector assembly platform, customized services, kits and assays
#416Engineered nucleic-acid targeting nucleic acids
#417STABILISATION OF POLYPEPTIDES
#418Liquid formulation of alpha-amylase
#419Peptide-mediated delivery of RNA-guided endonuclease into cells
#420Coexpression of CAS9 and TREX2 for targeted mutagenesis
#421Coagulation factor-targeting to TREM-like transcript 1 (TLT-1) on activated platelets
#422Nucleic acid modifying enzymes
#423PROTEINASE B AND LACTASE SOLUTION USING ITS PROPERTIES AND METHOD FOR PRODUCING THE SAME
#424Activated polyoxazolines and conjugates and compositions comprising the same
#425Conjugates of biomolecules to nanoparticles
#426Methods and apparatus for single molecule sequencing using energy transfer detection
#427Polymerase compositions and methods
#428Therapeutic fusion proteins
#429Histidyl-tRNA synthetase-Fc conjugates
#430Polymer-encased nanodiscs with improved buffer compatibility
#431Intracellular genomic transplant and methods of therapy
#432Intracellular genomic transplant and methods of therapy
#433Technology for the Preparation of Microparticles
#434Preparation of multi-hapten mutant G6PDH conjugates and their use for detection of multiple analytes
#435Excipient compounds for protein processing
#436Targeting of glycoprotein therapeutics
#437Intracellular genomic transplant and methods of therapy
#438Conjugate of therapeutic enzymes
#439Engineered nucleic-acid targeting nucleic acids
#440Amylases and glucoamylases, nucleic acids encoding them and methods for making and using them
#441Long-acting coagulation factors and methods of producing same
#442STABILIZING AGENT FOR PHARMACEUTICAL PROTEINS
#443Gold optimized CAR T-cells
#444Strain producing allose from fructose and method for producing allose using same
#445Enzyme Composition for DNA End Repair, Adenylation, Phosphorylation
#446Universal N-glycan binding reagent
#447Enzyme-pore constructs
#448RNase H-Based Assays Utilizing Modified RNA Monomers
#449PSMA binding ligand-linker conjugates and methods for using
#450Administration of kynurenine depleting enzymes for tumor therapy
#451MODIFICATIONS OF PEPTIDE COMPOSITIONS TO INCREASE STABILITY AND DELIVERY EFFICIENCY
#452Antibodies for detecting redox modulated proteins
#453Conjugates of tumor necrosis factor inhibitors to functionalized polymers
#454Compositions comprising a polypeptide having cellulolytic enhancing activity and a heterocyclic compound and uses thereof
#455High concentration alpha-glucosidase compositions for the treatment of pompe disease
#456METHODS AND KITS FOR QUALITY CONTROL
#457Manipulation of nuclear architecture
#458Protease variants and polynucleotides encoding same
#459Fusion polymerase and method for using the same
#460Covalent modification of biological macromolecules
#461Pegylated L-Asparaginase
#462Engineered nucleic-acid targeting nucleic acids
#463Using RNA-guided FokI nucleases (RFNs) to increase specificity for RNA-guided genome editing
#464Purification of polymerase complexes
#465Stabilizer for preserving biological samples
#466Apparatus and method for dehydrating biological materials with freezing and microwaving
#467Human-enzyme mediated depletion of homocysteine for treating patients with hyperhomocysteinemia and homocystinuria
#468RNA-guided gene editing and gene regulation
#469Processable single chain molecules and polypeptides made using same
#470Engineered heme-binding compositions and uses thereof
#471MODIFIED SULFAMIDASE AND PRODUCTION THEREOF
#472Methods to create chemically-induced dimerizing protein systems for regulation of cellular events
#473Compositions and methods for treatment of homocystinuria
#474Engineered nucleic-acid targeting nucleic acids
#475Chemically modified cystathionine beta-synthase enzyme for treatment of homocystinuria
#476Chemically ligated RNAs for CRISPR/Cas9-1gRNA complexes as antiviral therapeutic agents
#477MULTIPLEXED TAGMENTATION
#478FORMULATIONS OF PEGYLATED ARGININE DEIMINASE
#479Pregabalin immunoassays
#480Assays for screening activity of modulators of members of the hydroxy steroid (17-beta) dehydrogenase (HSD17B) family
#481Immunogenic compositions and reagents for preparing
#482Chimeric DNA:RNA Guide for High Accuracy Cas9 Genome Editing
#483CRISPR effector system based diagnostics
#484Genome editing enhancement
#485Generation and correction of a humanized mouse model with a deletion of dystrophin exon 44
#486Stabilization of dehydrogenases with stable coenzymes
#487Multi-functionalized polysaccharide compounds and use thereof for targeting the cation-independent mannose 6-phosphate receptor
#488GENERATION OF COMPLEX TRAIT LOCI IN SOYBEAN AND METHODS OF USE
#489Labeled enzyme compositions, methods and systems
#490Substituted 6,11-dihydro-5H-benzo[b]carbazoles as inhibitors of ALK and SRPK
#491SANDWICH GRANULE
#492Methods and compositions for protein purification and enzyme reaction
#493Systems and methods for one-shot guide RNA (ogRNA) targeting of endogenous and source DNA
#494Phospholipid nanogel for exoglycosidase enzyme stabilization
#495Compositions and methods of engineered CRISPR-Cas9 systems using split-nexus Cas9-associated polynucleotides
#496Tethering cysteine residues using cyclic disulfides
#497COMPOSITIONS FOR INCREASING POLYPEPTIDE STABILITY AND ACTIVITY, AND RELATED METHODS
#498Tethering cysteine residues using cyclic disulfides
#499Delivery of negatively charged proteins using cationic lipids
#500Fusion molecule based on TAA variant
#501Factor IX Polypeptides and Methods of Use Thereof
#502Factor IX polypeptides and methods of use thereof
#503Compounds for use in PCR systems and applications thereof
#504Bacteriophage recombination followed by blockage of non-recombinant bacteriophage replication
#505Mutant hydrolase proteins with enhanced kinetics and functional expression
#506AGGREGATE-FREE URATE OXIDASE FOR PREPARATION OF NON-IMMUNOGENIC POLYMER CONJUGATES
#507Recombinant K1-5 bacteriophages and uses thereof
#508HSD17B13 variants and uses thereof
#509Synthon Formation
#510HSD17B13 variants and uses thereof
#511Increasing specificity for RNA-guided genome editing
#512LENTIVIRUS AND NON-INTEGRATING LENTIVIRUS AS VIRAL VECTOR TO DELIVER CRISPR THERAPEUTIC
#513Factor IX Polypeptides and Methods of Use Thereof
#514Systems and methods for one-shot guide RNA (ogRNA) targeting of endogenous and source DNA
#515MODIFIED FNCAS9 PROTEIN AND USE THEREOF
#516Glycopolysialylation of non-blood coagulation proteins
#517Processing of a modified foot-and-mouth disease virus P1 polypeptide by an alternative protease
#518ALBUMIN FUSION PROTEINS
#519Method for producing maltitol, with an increased yield
#520DNA editing using relatively long single-stranded DNA and CRISPR/Cas9 to increase success rate in methods for preparing transgenic embryos and animals
#521SELF-ASSEMBLING MOLECULAR NANOSYSTEM FOR TARGETED DNA AND GENE DELIVERY
#522Compositions comprising nucleic acids and methods of using the same
#523Therapeutic nuclease compositions and methods
#524Cellulolytic compositions comprising monooxygenase polysaccharide enzymes with improved activity
#525Antigen-specific tolerance and compositions for induction of same
#526Compositions for generation of immune tolerance to specific antigens
#527Compositions for inducing antigen-specific tolerance
#528Chemical crosslinkers
#529Modified CRISPR RNA and modified single CRISPR RNA and uses thereof
#530Engineered enzymes with methionine-gamma-lyase enzymes and pharmacological preparations thereof
#531Vectors
#532ACETOLACTATE DECARBOXYLASE
#533RUBBER-LIKE MATERIAL FOR THE IMMOBILIZATION OF PROTEINS AND ITS USE IN LIGHTING, DIAGNOSIS AND BIOCATALYSIS
#534Unbiased identification of double-strand breaks and genomic rearrangement by genome-wide insert capture sequencing
#535Method for making site-directed modification to plant genomes by using non-inheritable materials
#536Gene expression in Bacteroides
#537Compositions and methods for delivery of a polynucleotide into a plant
#538INDUCIBLE DIMERIZATION OF RECOMBINASES
#539Site-specific polyethylene glycolylated (pegylated) asparaginase, preparation method therefor and use thereof
#540Methods and compositions for efficient delivery of nucleic acids and RNA-based antimicrobials
#541Proteome Editing System and A Biomarker of Veev Infection
#542Stabilized lactate responsive enzymes, electrodes and sensors, and methods for making and using the same
#543Composition and method for the protection of proteins, cell components and cells during temperature stress
#544PORE-FORMING PROTEIN CONJUGATE COMPOSITIONS AND METHODS
#545Treatment methods using DNA editing with single-stranded DNA
#546Cell sorting
#547Methods and compositions for the treatment of cellulosic biomass and products produced thereby
#548Chemically modified guide RNAs for CRISPR/CAS-mediated gene regulation
#549Method for obtaining a biomass of a microalga of the species enriched in superoxide dismutase (SOD)
#550PROTEIN AGGREGATION INHIBITOR
#551Sensor systems for target ligands and uses thereof
#552Enzyme-based protein separation and enrichment from soy meal, wheat meal, and other protein-rich materials derived from plant seeds, fruits and other biomass
#553CRISPR mediated in vivo modeling and genetic screening of tumor growth and metastasis
#554Methods for modifying genomic DNA
#555CRISPR/CAS-RELATED METHODS, COMPOSITIONS AND COMPONENTS
#556Methods And Compositions For PCR
#557Long-acting coagulation factors and methods of producing same
#558Reaction mixtures
#559Compositions for treating pathological calcification conditions, and methods using same
#560Gold optimized CAR T-cells
#561Compositions for treating pathological calcification conditions, and methods using same
#562Compositions for treating pathological calcification conditions, methods, and host cells using the same
#563Biofunctional materials
#564Treatment of Cellulosic Material and Enzymes Useful Therein
#565Reagents and methods for esterification
#566Technology for the Preparation of Microparticles
#567Nanoparticle-protein complex for intracellular protein delivery
#568Heteroaryl compounds and uses thereof
#569Nanocaged enzymes with enhanced catalytic activity and increased stability
#570Combination cancer immunotherapies with arginine depletion agents
#571Innovative discovery of therapeutic, diagnostic, and antibody compositions related to protein fragments of phenylalanyl-beta-tRNA synthetases
#572Method of producing and processing diamines from an engineered microorganism
#573Inhibitors of kidney-type glutaminase, GLS-1
#574Methods and compositions for enriching compositions for polymerase enzyme complexes
#575Multi-enzyme conjugate, method for preparing the same and method for preparing organic compound using the same
#576Methods and compositions for regulation of transgene expression
#577RNase H-Based Assays Utilizing Modified RNA Monomers
#578Factor VII conjugates
#579DELIVERY, USE AND THERAPEUTIC APPLICATIONS OF CRISPR SYSTEMS AND COMPOSITIONS FOR GENOME EDITING AS TO HEMATOPOIETIC STEM CELLS (HSCs)
#580Escorted and functionalized guides for CRISPR-Cas systems
#581Methods and compositions for single chain variable region ENOX2 antibodies for cancer detection and diagnosis
#582STABILIZED ENZYME COMPOSITIONS
#583Compositions for treating pathological calcification conditions, and methods using same
#584Compositions for treating pathological calcification conditions, and methods using same
#585ENZYME-PORE CONSTRUCTS
#586Compositions and methods of engineered CRISPR-CAS9 systems using split-nexus CAS9-associated polynucleotides
#587Compositions and methods of engineered CRISPR-Cas9 systems using split-nexus Cas9-associated polynucleotides
#588CHIMERIC PROTEIN
#589Peptide-mediated delivery of RNA-guided endonuclease into cells
#590Multi-domain enzymes having cutinase activity, compositions comprising same and uses thereof
#591Lysosomal targeting of enzymes, and uses thereof
#592Using RNA-guided FokI nucleases (RFNs) to increase specificity for RNA-guided genome editing
#593Innovative discovery of therapeutic, diagnostic, and antibody compositions related to protein fragments of histidyl-tRNA synthetases
#594Methods for coupling targeting peptides onto recombinant lysosomal enzymes for improved treatments of lysosomal storage diseases
#595ENZYME IMMOBILIZATION USING IRON OXIDE YOLK-SHELL NANOSTRUCTURE
#596Polypeptides Having Dextranase Activity and Polynucleotides Encoding Same
#597COMPOSITIONS AND METHODS COMPRISING GLYCYL-TRNA SYNTHETASES HAVING NON-CANONICAL BIOLOGICAL ACTIVITIES
#598Methods and apparatus for single molecule sequencing using energy transfer detection
#599Protected guide RNAS (PGRNAS)
#600Compositions and methods relating to synthetic RNA polynucleotides created from synthetic DNA oligonucleotides