ClassID:

112743

C12Q2525/117 - CPC Classification

Classification description:

Reactions involving modified oligonucleotides, nucleic acids, or nucleotides; Modifications characterised by incorporating modified base

Recent Application in this class:
#1
20260062736
2026-03-05

WHOLE TRANSCRIPTOME ANALYSIS IN SINGLE CELLS

#2
20250223650
2025-07-10

METHODS OF DETECTING 5-HYDROXYMETHYLCYTOSINE AND DIAGNOSING OF CANCER

#3
20240417785
2024-12-19

ENHANCEMENT OF NUCLEIC ACID POLYMERIZATION BY MINOR GROOVE BINDING MOIETIES

#4
20240218431
2024-07-04

SYSTEMS AND METHODS FOR IDENTIFYING AND DISTINGUISHING GENETIC SAMPLES

#5
20240158870
2024-05-16

Analysis of Chromatin Using a Nicking Enzyme

#6
20230416804
2023-12-28

WHOLE TRANSCRIPTOME ANALYSIS IN SINGLE CELLS

#7
20230332223
2023-10-19

TUNNELING JUNCTIONS FOR SEQUENCING

#8
20230103381
2023-04-06

Reusable initiators for synthesizing nucleic acids

#9
20230092081
2023-03-23

SINGLE-STRAND BINDING PROTEIN

#10
20220348998
2022-11-03

METHODS FOR LABELLING NUCLEIC ACIDS

#11
20220290224
2022-09-15

METHOD FOR IN SITU DETERMINATION OF NUCLEIC ACID PROXIMITY

#12
20220195497
2022-06-23

HYBRIDIZING all-LNA OLIGONUCLEOTIDES

#13
20220180970
2022-06-09

Methods and systems for determining haplotypes and phasing of haplotypes

#14
20220180969
2022-06-09

METHODS AND SYSTEMS FOR DETERMINING HAPLOTYPES AND PHASING OF HAPLOTYPES

#15
20220177950
2022-06-09

WHOLE TRANSCRIPTOME ANALYSIS IN SINGLE CELLS

#16
20220056537
2022-02-24

Analysis of chromatin using a nicking enzyme

#17
20210403978
2021-12-30

Methods for detecting agglutination and compositions for use in practicing the same

#18
20210155976
2021-05-27

HYBRIDIZING ALL-LNA OLIGONUCLEOTIDES

#19
20210054435
2021-02-25

Methods of nucleic acid sample preparation

#20
20210032683
2021-02-04

DNA-tagged methanol responsive polymer for single-stranded nucleic acid production

#21
20210017571
2021-01-21

Methods of nucleic acid sample preparation for analysis of DNA

#22
20200325533
2020-10-15

Mapping the location, type and strand of damaged and/or mismatched nucleotides in double-stranded DNA

#23
20200102591
2020-04-02

Methods for the Imaging of Nucleic Acid Sequences

#24
20200087717
2020-03-19

Systems and methods for identifying and distinguishing genetic samples

#25
20200058369
2020-02-20

Quantitative Cluster Analysis Method Of Target Protein By Using Next-Generation Sequencing And Use Thereof

#26
20190390269
2019-12-26

METHOD FOR DETECTING KNOWN NUCLEOTIDE MODIFICATIONS IN AN RNA

#27
20190390267
2019-12-26

Tunneling junctions for sequencing

#28
20190376122
2019-12-12

Single-strand binding protein

#29
20190284621
2019-09-19

THERAPEUTIC OLIGONUCLEOTIDES CAPTURE AND DETECTION

#30
20190275492
2019-09-12

Reusable initiators for synthesizing nucleic acids

#31
20190249239
2019-08-15

CONVERTIBLE ADAPTERS

#32
20190211404
2019-07-11

Analysis of chromatin using a nicking enzyme

#33
20190203283
2019-07-04

Methods for labelling nucleic acids

#34
20190177780
2019-06-13

VISUALIZING MODIFIED NUCLEOTIDES AND NUCLEIC ACID INTERACTIONS IN SINGLE CELLS

#35
20190135851
2019-05-09

Massive parallel method for decoding DNA and RNA

#36
20190135850
2019-05-09

Massive parallel method for decoding DNA and RNA

#37
20190127790
2019-05-02

3′-OH unblocked, fast photocleavable terminating nucleotides and methods for nucleic acid sequencing

#38
20190092806
2019-03-28

Massive parallel method for decoding DNA and RNA

#39
20190092805
2019-03-28

Massive parallel method for decoding DNA and RNA

#40
20190085016
2019-03-21

Massive parallel method for decoding DNA and RNA

#41
20190085015
2019-03-21

Massive parallel method for decoding DNA and RNA

#42
20190085014
2019-03-21

Massive parallel method for decoding DNA and RNA

#43
20190062807
2019-02-28

Substrates and methods useful in sequencing

#44
20190031706
2019-01-31

Massive parallel method for decoding DNA and RNA

#45
20190031705
2019-01-31

Massive parallel method for decoding DNA and RNA

#46
20190031704
2019-01-31

Massive parallel method for decoding DNA and RNA

#47
20180363046
2018-12-20

Compositions and methods for detecting a nucleic acid sequence in a sample comprising a primer oligonucleotide with a 3′-terminal region comprising a 2′-modified nucleotide

#48
20180327855
2018-11-15

METHODS OF DETECTING 5-HYDROXYMETHYLCYTOSINE AND DIAGNOSING OF CANCER

#49
20180322243
2018-11-08

Methods and systems for determining haplotypes and phasing of haplotypes

#50
20180320219
2018-11-08

Nucleotide analogs

#51
20180305737
2018-10-25

Method for fragmenting and ligating adapters onto a nucleic acid and kit for performing the same

#52
20180258481
2018-09-13

Method for nucleic acid sequencing

#53
20180201642
2018-07-19

Massive parallel method for decoding DNA and RNA

#54
20180201641
2018-07-19

Cytidine-5-carboxamide modified nucleotide compositions and methods related thereto

#55
20180164280
2018-06-14

MODIFIED NUCLEIC ACIDS FOR NANOPORE ANALYSIS

#56
20180141970
2018-05-24

Process using dual specificity oligonucleotide and dual specificity oligonucleotide

#57
20180111959
2018-04-26

Compositions and methods for sequencing nucleic acids

#58
20180100181
2018-04-12

Methods for detecting agglutination and compositions for use in practicing the same

#59
20180094310
2018-04-05

Compositions and methods for detecting a nucleic acid sequence in a sample comprising a primer oligonucleotide with a 3′-terminal region comprising a 2′-modified nucleotide

#60
20180087104
2018-03-29

Genomewide unbiased identification of DSBs evaluated by sequencing (GUIDE-seq)

#61
20180044660
2018-02-15

Methods, compositions, and kits for generating rRNA-depleted samples or isolating rRNA from samples

#62
20170362649
2017-12-21

Method for in situ determination of nucleic acid proximity

#63
20170362647
2017-12-21

Visualizing modified nucleotides and nucleic acid interactions in single cells

#64
20170327886
2017-11-16

3′-OH unblocked, fast photocleavable terminating nucleotides and methods for nucleic acid sequencing

#65
20170313737
2017-11-02

Massive parallel method for decoding DNA and RNA

#66
20170275671
2017-09-28

Methods and solutions for inhibiting undesired cleaving of labels

#67
20170260581
2017-09-14

Preservation of information related to genomic DNA methylation

#68
20160369336
2016-12-22

3′-OH unblocked, fast photocleavable terminating nucleotides and methods for nucleic acid sequencing

#69
20160326207
2016-11-10

Method of suppressing formation of photocrosslink, and photoreactive nucleic acid in which auto-crosslink formation is suppressed

#70
20160264612
2016-09-15

Massive parallel method for decoding DNA and RNA

#71
20160208313
2016-07-21

Synthesis of four-color 3′-O-allyl modified photocleavable fluorescent nucleotides and related methods

#72
20150259733
2015-09-17

Methods and compositions for amplification and sequencing of difficult DNA templates

#73
20150225785
2015-08-13

Compositions and methods for nucleotide sequencing

#74
20150197800
2015-07-16

Massive parallel method for decoding DNA and RNA

#75
20150176074
2015-06-25

3′-OH unblocked, fast photocleavable terminating nucleotides and methods for nucleic acid sequencing

#76
20150140559
2015-05-21

Nucleotides and nucleosides and methods for their use in DNA sequencing

#77
20150086994
2015-03-26

Polymerase-nucleic acid complex

#78
20140370498
2014-12-18

Compositions and methods for nucleotide sequencing

#79
20140322821
2014-10-30

Molecule capable of binding to adrenocorticotropic hormone, and use thereof

#80
20140206553
2014-07-24

Massive parallel method for decoding DNA and RNA

#81
20140170666
2014-06-19

Methods, compositions and kits for the improved detection of small RNA molecules

#82
20140024537
2014-01-23

Methods and systems for determining haplotypes and phasing of haplotypes

#83
20140004509
2014-01-02

KIT FOR ISOTHERMAL DNA AMPLIFICATION STARTING FROM AN RNA TEMPLATE

#84
20140004508
2014-01-02

Method for isothermal DNA amplification starting from an RNA template

#85
20130316352
2013-11-28

Methods and compositions for amplification and sequencing of difficult DNA templates

#86
20130295558
2013-11-07

Method of detecting ethylated thymidine DNA adducts

#87
20130078630
2013-03-28

Use of G-clamp for improved allele-specific PCR

#88
20130071836
2013-03-21

COLON CANCER BIOMARKER DISCOVERY

#89
20130035237
2013-02-07

Nucleotides and nucleosides and methods for their use in DNA sequencing

#90
20130029853
2013-01-31

CLASSIFICATION OF NUCLEIC ACID TEMPLATES

#91
20120322691
2012-12-20

Pooled adapter strategy for reducing bias in small RNA characterization

#92
20120308594
2012-12-06

HCV CLADE AND PROTOTYPE SEQUENCES THEREOF

#93
20120295808
2012-11-22

Solid support assay systems and methods utilizing non-standard bases

#94
20120270210
2012-10-25

Method and reagent for gene sequence analysis

#95
20120252691
2012-10-04

Modified nucleotides methods and kits

#96
20120252009
2012-10-04

Methods and compositions for enriching either target polynucleotides or non-target polynucleotides from a mixture of target and non-target polynucleotides

#97
20120244535
2012-09-27

Functionalized 3-alkynyl pyrazolopyrimidine analogues as universal bases and methods of use

#98
20120244525
2012-09-27

Oligonucleotide Adapters: Compositions and Methods of Use

#99
20120237943
2012-09-20

Method for differentiation of polynucleotide strands

#100
20120231462
2012-09-13

Artificial base pair capable of forming specific base pair

#101
20120208178
2012-08-16

Probes comprising fluorescent artificial nucleobases and use thereof for detection of single base alteration

#102
20120156680
2012-06-21

Synthesis of four-color 3′-O-allyl modified photocleavable fluorescent nucleotides and related methods

#103
20120149593
2012-06-14

METHODS AND ARRAYS FOR PROFILING DNA METHYLATION

#104
20120142006
2012-06-07

MASSIVE PARALLEL METHOD FOR DECODING DNA AND RNA

#105
20120135473
2012-05-31

Processes using dual specificity oligonucleotide and dual specificity oligonucleotide

#106
20120115752
2012-05-10

Method for generating aptamers with improved off-rates

#107
20120058518
2012-03-08

Nucleic acid isothermal amplification method

#108
20120052489
2012-03-01

Methods and compositions for sequencing nucleic acid using charge

#109
20110312040
2011-12-22

Preferential amplification of mRNA over DNA using chemically modified primers

#110
20110311968
2011-12-22

Allele-specific amplification of nucleic acids

#111
20110300534
2011-12-08

Compositions and methods for sequencing nucleic acids

#112
20110287431
2011-11-24

Modified oligonucleotides and applications thereof

#113
20110262917
2011-10-27

Modified nucleotides

#114
20110251107
2011-10-13

G-QUADRUPLEX BINDING ASSAYS AND COMPOUNDS THEREFOR

#115
20110229920
2011-09-22

SCREENING METHODS FOR IDENTIFYING SPECIFIC STAPHYLOCOCCUS AUREUS INHIBITORS

#116
20110217791
2011-09-08

METHOD FOR QUANTIFYING OR DETECTING DNA

#117
20110201524
2011-08-18

Preservation of information related to genomic DNA methylation

#118
20110189674
2011-08-04

METHOD FOR QUANTIFYING OR DETECTING DNA

#119
20110183857
2011-07-28

Human single nucleotide polymorphisms within CODIS loci D13S317, TH01, vWA, D12S391, and D6S1043

#120
20110183320
2011-07-28

Methods for identifying nucleic acid modifications

#121
20110177496
2011-07-21

Field-switch sequencing

#122
20110144319
2011-06-16

Modified oligonucleotides and applications thereof

#123
20110136098
2011-06-09

Methods for simplifying microbial nucleic acids by chemical modification of cytosines

#124
20110124054
2011-05-26

Methods and compositions for inhibiting undesired cleaving of labels

#125
20110124053
2011-05-26

Polymerase incorporation of non-standard nucleotides

#126
20110097764
2011-04-28

Amplification primers with non-standard bases for increased reaction specificity

#127
20110076728
2011-03-31

Target amplification and sequencing with primers comprising triplex forming monomer units

#128
20110059450
2011-03-10

Labeled nucleotide analogs and uses therefor

#129
20110053782
2011-03-03

DNA capable of being amplified by PCR with high selectivity and high efficiency

#130
20110045485
2011-02-24

ANALYTICAL METHOD AND KIT

#131
20110040081
2011-02-17

METHODS, COMPOSITIONS, AND KITS FOR GENERATING rRNA-DEPLETED SAMPLES OR ISOLATING rRNA FROM SAMPLES

#132
20110009607
2011-01-13

METHOD FOR PREPARING DNA FRAGMENT HAVING STICKY END

#133
20110003700
2011-01-06

ELIMINATION OF CONTAMINANTS ASSOCIATED WITH NUCLEIC ACID AMPLIFICATION

#134
20110003284
2011-01-06

Aberrantly methylated genes in pancreatic cancer

#135
20100317012
2010-12-16

Massive parallel method for decoding DNA and RNA

#136
20100304442
2010-12-02

Methods, compositions and kits for the improved detection of small RNA molecules

#137
20100297647
2010-11-25

POLYMERASE-BASED SINGLE-MOLECULE SEQUENCING

#138
20100291637
2010-11-18

METHOD FOR MODIFYING NUCLEOTIDE CHAIN

#139
20100285598
2010-11-11

Artificial base pairs and uses thereof

#140
20100228017
2010-09-09

OLIGONUCLEOTIDES CONTAINING PYRAZOLO[3,4-D] PYRIMIDINES FOR HYBRIDIZATION AND MISMATCH DISCRIMINATION

#141
20100222563
2010-09-02

Method for modifying nucleic acid bases, and nucleic acid base-modified product

#142
20100221785
2010-09-02

Isothermal strand displacement amplification using primers containing a non-regular base

#143
20100221716
2010-09-02

Methods for identifying nucleic acid modifications

#144
20100190972
2010-07-29

Heteropolynucleotide duplexes with purine—purine base pairing

#145
20100186124
2010-07-22

TARGETED NUCLEOTIDE EXCHANGE WITH LNA MODIFIED OLIGONUCLEOTIDES

#146
20100184159
2010-07-22

Compositions, Methods, and Kits for Selective Amplification of Nucleic Acids

#147
20100184074
2010-07-22

UNIVERSAL NUCLEOTIDES FOR NUCLEIC ACID ANALYSIS

#148
20100167938
2010-07-01

Nucleic acid sequencing and electronic detection

#149
20100159531
2010-06-24

Methods and solutions for inhibiting undesired cleaving of labels

#150
20100151455
2010-06-17

Use of base-modified deoxynucleoside triphosphates to improve nucleic acid detection

#151
20100143922
2010-06-10

METHODS FOR REDUCING OVER-REPRESENTATION OF FRAGMENT ENDS

#152
20100120157
2010-05-13

Methods of Using Sulfur Nucleophiles as Improved Alternatives to Sodium Bisulfite for Methylated DNA Analysis

#153
20100112712
2010-05-06

Modified oligonucleotides and applications thereof

#154
20100105028
2010-04-29

PROBE FOR DETECTING NUCLEIC ACIDS

#155
20100099110
2010-04-22

Allele-specific amplification

#156
20100092957
2010-04-15

Compositions and methods for nucleotide sequencing

#157
20100086908
2010-04-08

METHODS FOR THE DETECTION OF RESPIRATORY VIRUSES

#158
20100075307
2010-03-25

Analyte detection assays

#159
20100063743
2010-03-11

Methods and compositions for base calling nucleic acids

#160
20100055780
2010-03-04

TARGETED NUCLEOTIDE EXCHANGE WITH PROPYNYL MODIFIED OLIGONUCLEOTIDES

#161
20100041041
2010-02-18

Nucleotides and nucleosides and methods for their use in DNA sequencing

#162
20100041029
2010-02-18

Synthesis of four color 3′O-allyl, modified photocleavable fluorescent nucleotides and related methods

#163
20100036111
2010-02-11

Method for nucleic acid replication and novel artificial base pairs

#164
20100035253
2010-02-11

Methods And Compositions For Incorporating Nucleotides

#165
20100022411
2010-01-28

Method and sequences for determinate nucleic acid hybridization

#166
20100015670
2010-01-21

Method of modifying nucleotide chain

#167
20090307805
2009-12-10

ALTERNATIVE NUCLEOTIDES FOR IMPROVED TARGETED NUCLEOTIDE EXCHANGE

#168
20090275039
2009-11-05

Methods for detection and quantification of small RNA

#169
20090270601
2009-10-29

Differential detection of single nucleotide polymorphisms

#170
20090226924
2009-09-10

Modified oligonucleotides and applications thereof

#171
20090186343
2009-07-23

METHODS FOR PREPARING MODIFIED BIOMOLECULES, MODIFIED BIOMOLECULES AND METHODS FOR USING SAME

#172
20090171076
2009-07-02

Compositions and methods for the use of FMOC derivatives in DNA/RNA synthesis

#173
20090148846
2009-06-11

Modified oligonucleotides and applications thereof

#174
20090098549
2009-04-16

Selex and photoSELEX

#175
20090064377
2009-03-05

METHOD AND MEANS FOR TARGETED NUCLEOTIDE EXCHANGE

#176
20090042732
2009-02-12

Methods for simplifying microbial nucleic acids by chemical modification of cytosines

#177
20090018324
2009-01-15

Labeled nucleotide analogs and uses therefor

#178
20090005334
2009-01-01

Nucleic acid derivatives

#179
20080319179
2008-12-25

Massive parallel method for decoding DNA and RNA

#180
20080305478
2008-12-11

Processes using dual specificity oligonucleotide and dual specificity oligonucleotide

#181
20080274462
2008-11-06

Universal bases for nucleic acid analyses, methods for using universal bases, and kits comprising universal bases

#182
20080233588
2008-09-25

Analytical method and kit

#183
20080227104
2008-09-18

Primer, primer set, and nucleic acid amplification method and mutation detection method using the same

#184
20080199868
2008-08-21

Massive parallel method for decoding DNA and RNA

#185
20080131895
2008-06-05

Massive parallel method for decoding DNA and RNA

#186
20080114161
2008-05-15

Modified probe molecules having self-complementary regions

#187
20080102450
2008-05-01

Detecting DNA methylation patterns in genomic DNA using bisulfite-catalyzed transamination of CpGS

#188
20080090247
2008-04-17

Method for detecting a structured target

#189
20080090246
2008-04-17

Amplification and detection method

#190
20080020378
2008-01-24

Fluorescent base analogues' usage in the characterization of nucleic acid molecules and their interactions

#191
20070281308
2007-12-06

Phosphotriester-modified oligonucleotide primers for nucleic acid amplification

#192
20070212695
2007-09-13

Compositions, methods, and kits for selective amplification of nucleic acids

#193
20070190564
2007-08-16

Universal nucleotides for nucleic acid analysis

#194
20070190546
2007-08-16

Methods and compositions for sequencing a nucleic acid

#195
20070179289
2007-08-02

Compositions and methods for the use of FMOC derivatives in DNA/RNA synthesis

#196
20070122818
2007-05-31

Gene methylation assay controls

#197
20070117112
2007-05-24

Materials and methods for the generation of fully 2′-modified nucleic acid transcripts

#198
20070117104
2007-05-24

Nucleotide analogs

#199
20070099187
2007-05-03

Nucleic acid array

#200
20070087361
2007-04-19

Solid support assay systems and methods utilizing non-standard bases

#201
20070082349
2007-04-12

Photocrosslinking probes and uses of the same

#202
20070072196
2007-03-29

Fluorescent nucleotide analogs and uses therefor

#203
20070065834
2007-03-22

Method and sequences for determinate nucleic acid hybridization

#204
20070058811
2007-03-15

Method and apparatus to facilitate transmission of an encrypted rolling code

#205
20070048773
2007-03-01

Detection of polyphosphate using fluorescently labeled polyphosphate acceptor substrates

#206
20070048758
2007-03-01

IMPROVED PRIMER-BASED AMPLIFICATION METHODS

#207
20070042389
2007-02-22

Method and sequences for determinate nucleic acid hybridization

#208
20070015156
2007-01-18

Aberrantly methylated genes in pancreatic cancer

#209
20060281099
2006-12-14

Q-melt for polymorphism detection

#210
20060234254
2006-10-19

COLON CANCER BIOMARKER DISCOVERY

#211
20060223064
2006-10-05

Methods of nucleic acid analysis

#212
20060216708
2006-09-28

Method for lowering both sequence variations and increase of base line effects in a diagnostic hybridisation assay, assay for performing such a method and probe for use in the assay

#213
20060183149
2006-08-17

Detection of nucleic acid sequence differences using the ligase detection reaction with addressable arrays

#214
20060148751
2006-07-06

Nucleic acid derivatives

#215
20060147963
2006-07-06

Detection of polynucleotides on nucleic acid arrays using azido-modified triphosphate nucleotide analogs

#216
20060147924
2006-07-06

Population of nucleic acids including a subpopulation of lna oligomers

#217
20060099634
2006-05-11

Simplified biological evaluation method of natural and artificial chemicals by using DNA injury index and apparatus therefor

#218
20060084079
2006-04-20

Modified oligonucleotides and applications thereof

#219
20060078936
2006-04-13

Solid support assay systems and methods utilizing non-standard bases

#220
20060063189
2006-03-23

Methods of using sulfur nucleophiles as improved alternatives to sodium bisulfite for methylated DNA analysis

#221
20060009628
2006-01-12

Modified oligonucleotides for mismatch discrimination

#222
20060003349
2006-01-05

Tleveling compositions

#223
20050266456
2005-12-01

Field-switch sequencing

#224
20050239087
2005-10-27

Multiply-primed amplification of nucleic acid sequences

#225
20050233358
2005-10-20

Electrochemical detection of nucleic acid hybridization

#226
20050221304
2005-10-06

Modified random primers for probe labeling

#227
20050208576
2005-09-22

Sorting and immobilization system for nucleic acids using synthetic binding systems

#228
20050164182
2005-07-28

Nucleotide analogues

#229
20050075491
2005-04-07

TM leveling methods

#230
20050069870
2005-03-31

HCV clade and prototype sequences thereof

#231
20050059003
2005-03-17

Isothermal chimeric primer nucleic acid amplification methods using blocking oglionucleotide

#232
20050053979
2005-03-10

Combinatorial nucleobase oligomers comprising universal base analogues and methods for making and using same

#233
20050053972
2005-03-10

Method for identifying polymorphisms

#234
20050037396
2005-02-17

Universal bases for nucleic acid analyses, methods for using universal bases, and kits comprising universal bases

#235
20050032055
2005-02-10

Methods of making nucleic acid molecules with reduced secondary structure

#236
20050032053
2005-02-10

Nucleic acid molecules with reduced secondary structure

#237
18335851
2025-05-27

High-throughput multiplexed sensitivity and resistance assay

#238
16216266
2020-11-10

Amplification of oligonucleotides containing non-standard nucleotides

#239
15997339
2020-12-15

Polymerase incorporation of non-standard nucleotides

#240
15997325
2019-09-17

In vivo conversion of nucleosides in plasmid DNA

#241
14746243
2017-05-02

Amplification of oligonucleotides containing non-standard nucleotides by polymerase chain reactions

#242
14524227
2016-02-02

Self-avoiding molecular recognition systems in DNA priming

#243
14138532
2015-06-23

Processes for synthesizing DNA with non-standard nucleotides

#244
14048671
2016-03-29

Inexpensive autonomous assembly of ultra-large (UL) DNA constructs

#245
12653613
2016-05-10

Processes replacing standard nucleotides by non-standard nucleotides and non-standard nucleotides by standard nucleotides in DNA

#246
11377136
2015-06-02

Field switch sequencing