ClassID:

114469

C12Y114/16001 - CPC Classification

Classification description:

Oxidoreductases acting on paired donors, with incorporation or reduction of molecular oxygen (1.14) with reduced pteridine as one donor, and incorporation of one atom of oxygen (1.14.16) Phenylalanine 4-monooxygenase (1.14.16.1)

Recent Application in this class:
#1
20250381300
2025-12-18

AAV PIGGYBAC TRANSPOSON POLYNUCLEOTIDE COMPOSITIONS AND METHODS OF USE THEREFOR

#2
20250312488
2025-10-09

TARGETED INTEGRATION AT ALPHA-GLOBIN LOCUS IN HUMAN HEMATOPOIETIC STEM AND PROGENITOR CELLS

#3
20250312485
2025-10-09

COMPOSITIONS AND METHODS FOR THE MANAGEMENT AND TREATMENT OF PHENYLKETONURIA

#4
20250283030
2025-09-11

Biosynthesis of Phenylpropanoid Compounds

#5
20250179522
2025-06-05

HUMAN PAH EXPRESSION CASSETTE FOR TREATMENT OF PKU BY LIVER-DIRECTED GENE REPLACEMENT THERAPY

#6
20250090691
2025-03-20

ADENO-ASSOCIATED VIRUS COMPOSITIONS FOR RESTORING PAH GENE FUNCTION AND METHODS OF USE THEREOF

#7
20240285806
2024-08-29

STABLE EXPRESSION OF AAV VECTORS IN JUVENILE SUBJECTS

#8
20240207444
2024-06-27

LIPID NANOPARTICLES CONTAINING POLYNUCLEOTIDES ENCODING PHENYLALANINE HYDROXYLASE AND USES THEREOF

#9
20240141381
2024-05-02

COMPOSITIONS AND METHODS FOR TREATING PHENYLKETONURIA

#10
20240124850
2024-04-18

Auxotrophic Cells for Virus Production and Compositions and Methods of Making

#11
20240041789
2024-02-08

Process of Preparing mRNA-Loaded Lipid Nanoparticles

#12
20240026374
2024-01-25

CLOSED-ENDED DNA VECTORS AND USES THEREOF FOR EXPRESSING PHENYLALANINE HYDROXYLASE (PAH)

#13
20240009249
2024-01-11

ADIPOGENIC CELL COMPOSITIONS AND METHODS

#14
20230323390
2023-10-12

METHODS AND COMPOSITIONS FOR EXPRESSING PHENYLALANINE HYDROXYLASE

#15
20230235298
2023-07-27

PHENYLALANINE HYDROXYLASE VARIANTS AND USES THEREOF

#16
20230126159
2023-04-27

ENGINEERED BACTERIAL STRAINS COMPRISING A TRANSGENE

#17
20230055020
2023-02-23

ADENO ASSOCIATED VIRUS BASED GENE THERAPY FOR PHENYLKETONURIA

#18
20230050301
2023-02-16

MRNA THERAPY FOR PHENYLKETONURIA

#19
20230038295
2023-02-09

ADENO-ASSOCIATED VIRUS PACKAGING SYSTEMS

#20
20230024354
2023-01-26

NON-VIRAL DNA VECTORS AND USES THEREOF FOR EXPRESSING PHENYLALANINE HYDROXYLASE (PAH) THERAPEUTICS

#21
20220403398
2022-12-22

METHODS OF CELL SELECTION

#22
20220313760
2022-10-06

GENE THERAPY FOR TREATING PHENYLKETONURIA

#23
20220162643
2022-05-26

OPTIMIZED PHENYLANANINE HYDROXYLASE EXPRESSION

#24
20220160728
2022-05-26

GENE THERAPY METHODS

#25
20220112520
2022-04-14

Human PAH expression cassette for treatment of PKU by liver-directed gene replacement therapy

#26
20220073944
2022-03-10

MULTIMERIC CODING NUCLEIC ACID AND USES THEREOF

#27
20220047654
2022-02-17

PHARMABIOTIC TREATMENTS FOR METABOLIC DISORDERS

#28
20210393804
2021-12-23

Adeno-associated virus compositions for restoring PAH gene function and methods of use thereof

#29
20210348135
2021-11-11

GENERATION OF IMPROVED HUMAN PAH FOR TREATMENT OF SEVERE PKU BY LIVER-DIRECTED GENE REPLACEMENT THERAPY

#30
20210261983
2021-08-26

Methods of treating phenylketonuria

#31
20210246433
2021-08-12

VECTORS AND METHODS OF USE

#32
20210079372
2021-03-18

Optimized microbial cells for production of melatonin and other compounds

#33
20210040456
2021-02-11

Polynucleotides encoding phenylalanine hydroxylase for the treatment of phenylketonuria

#34
20200318081
2020-10-08

VECTORS WITH PROMOTER AND ENHANCER COMBINATIONS FOR TREATING PHENYLKETONURIA

#35
20200216823
2020-07-09

VECTORS AND METHODS OF USE

#36
20200172923
2020-06-04

Multimeric coding nucleic acid and uses thereof

#37
20200109375
2020-04-09

Compositions and methods for treating phenylketonuria

#38
20200087682
2020-03-19

Compositions and methods for treating phenylketonuria

#39
20200087650
2020-03-19

METHODS OF ATTACHING A MOLECULE-OF-INTEREST TO A MICROTUBE

#40
20200087649
2020-03-19

METHOD OF ATTACHING A CELL-OF-INTEREST TO A MICROTUBE

#41
20200069819
2020-03-05

STABLE EXPRESSION OF AAV VECTORS IN JUVENILE SUBJECTS

#42
20200056190
2020-02-20

TYROSINE PROTOTROPHY

#43
20190336550
2019-11-07

Gene therapy for treating Phenylketonuria

#44
20190249191
2019-08-15

Multimeric coding nucleic acid and uses thereof

#45
20190211314
2019-07-11

mRNA therapy for phenylketonuria

#46
20190119663
2019-04-25

Optimized microbial cells for production of melatonin and other compounds

#47
20180282774
2018-10-04

Microbial approach for the production of 5-hydroxytryptophan

#48
20180153822
2018-06-07

Process of Preparing mRNA-Loaded Lipid Nanoparticles

#49
20180064672
2018-03-08

Allosteric activators for treatment of phenylketonuria

#50
20180051262
2018-02-22

Messenger UNA molecules and uses thereof

#51
20170314041
2017-11-02

Multimeric coding nucleic acid and uses thereof

#52
20170240939
2017-08-24

Microbial approach for the production of 5-hydroxytryptophan

#53
20170073648
2017-03-16

MRNA therapy for phenylketonuria

#54
20170002481
2017-01-05

METHODS OF ATTACHING A MOLECULE-OF-INTEREST TO A MICROTUBE

#55
20160160236
2016-06-09

Methods of expressing products in mammalian cells

#56
20160144094
2016-05-26

Compositions, methods, and devices for dialysis

#57
20160130567
2016-05-12

MESSENGER UNA MOLECULES AND USES THEREOF

#58
20160120956
2016-05-05

COMPOSITION OF ERYTHROCYTES ENCAPSULATING PHENYLALANINE HYDROXYLASE AND THERAPEUTIC USE THEREOF

#59
20150110858
2015-04-23

MRNA therapy for phenylketonuria

#60
20130004504
2013-01-03

METHOD OF MODULATING PHENYLALANINE HYDROXYLASE STRUCTURE AND FUNCTION

#61
20120196321
2012-08-02

Selectable markers and related methods

#62
20110123573
2011-05-26

Methods and compositions for treating phenylketonuria

#63
20110081394
2011-04-07

Methods of attaching a molecule-of-interest to a microtube

#64
20110039296
2011-02-17

Method of attaching a cell-of-interest to a microtube

#65
20110028834
2011-02-03

Use of electrospun microtubes for drug delivery

#66
20070092501
2007-04-26

Compositions and methods relating to reduction of symptoms of autism

#67
20050147592
2005-07-07

Methods of treating amino acid metabolic disorders using recombinant adeno-associated virus virions