116858 ⎘
Hydrolases acting on peptide bonds, i.e. peptidases (3.4); Serine endopeptidases (3.4.21) Kexin (3.4.21.61), i.e. proprotein convertase subtilisin/kexin type 9
DOUBLE STRANDED RNAi AGENTS, COMPOSITIONS AND METHODS OF USE
#2RNAi Agent Targeting PCSK9 and Use Thereof
#3Methods for Preventing Cardiovascular Events Through Proprotein Convertase Subtilisin Kexin 9 (PCSK9) Reduction
#4GALNAC MONOMER COMPRISING RIBOSE RING OR DERIVATIVE STRUCTURE THEREOF AND USE THEREOF IN LIVER-TARGETED DELIVERY OF SMALL NUCLEIC ACID DRUGS
#5COMPOSITIONS AND METHODS FOR IN VIVO NUCLEASE-MEDIATED GENE TARGETING FOR THE TREATMENT OF GENETIC DISORDERS IN ADULT PATIENTS
#6LIPOSOMAL NANOCARRIER DELIVERY SYSTEM FOR TARGETING ACTIVE CD44 MOLECULE, PREPARATION METHOD THEREFOR, AND USES THEREOF
#7GalNAc Compound Containing Triazole Structure and Oligonucleotide Conjugate Thereof
#8METHOD FOR PREPARING ENHANCED CAR-T-CELLS BASED ON INTERFERING OR KNOCKING OUT HUMAN PCSK9 GENE AND APPLICATION THEREOF
#9DOUBLE STRANDED RNAi AGENTS, COMPOSITIONS AND METHODS OF USE
#10SIRNA TARGETING AND REGULATING PCSK9 GENE EXPRESSION AND USE THEREOF
#11RNAi Agents for Inhibiting Expression of Proprotein Convertase Subtilisin Kexin 9 (PCSK9), Pharmaceutical Compositions Thereof, and Methods of Use
#12LIPOLYTIC ENZYME VARIANTS
#13SMALL RNA AND USE THEREOF IN TREATMENT OF HYPERLIPIDEMIA
#14PCSK9 ENDONUCLEASE VARIANTS, COMPOSITIONS, AND METHODS OF USE
#15IMMUNOGENIC ANTI-FUNGAL POLYPEPTIDES, COMPOSITIONS AND METHODS THEREOF
#16ANTI-PCSK9 ANTIBODIES
#17DEGRADATION OF RNA BY THE LYSOSOMAL PATHWAY
#18DOUBLE STRANDED RNA TARGETING PROPROTEIN CONVERTASE SUBTILISIN KEXIN 9 (PCSK9) AND METHODS OF USE THEREOF
#19KEXIN-DERIVED VACCINES TO PREVENT OR TREAT FUNGAL INFECTIONS
#20NUCLEIC ACID TARGETING PROPROTEIN CONVERTASE SUBTILISIN/KEXIN 9 AND USES THEREOF
#21USE OF microRNA MIMICS TO INHIBIT OR TREAT LIVER DISEASE
#22ANTIBODY-GUIDED PCSK9-MIMICKING IMMUNOGENS LACKING 9-RESIDUE SEQUENCE OVERLAP WITH HUMAN PROTEINS
#23PEPTIDE VACCINES USABLE FOR HYPERCHOLESTEROLEMIA RELATED DISEASES
#24PCSK9 ENDONUCLEASE VARIANTS, COMPOSITIONS, AND METHODS OF USE
#25Anti-PCSK9 antibodies
#26Modulators of PCSK9 Expression
#27KEXIN-DERIVED VACCINES TO PREVENT OR TREAT FUNGAL INFECTIONS
#28COMPOSITIONS AND METHODS FOR THE TARGETING OF PCSK9
#29DUAL TARGETING siRNA AGENTS
#30APPLICATION OF PCSK9 INHIBITORS IN THE PREPARATION OF DRUGS FOR THE TREATMENT OF INFLAMMATORY AND IMMUNE DISEASES
#31ANTI-PCSK9 ANTIBODIES
#32Compositions comprising a PCSK9 peptide conjugated to a qbeta carrier and methods of using the same
#33KEXIN-DERIVED VACCINES TO PREVENT OR TREAT FUNGAL INFECTIONS
#34Peptide vaccines for hypercholesterolemia related diseases
#35Methods for Preventing Cardiovascular Events Through Proprotein Convertase Subtilisin Kexin 9 (PCSK9) Reduction
#36Modulators of PCSK9 expression
#37MULTIVALENT HETEROMULTIMER SCAFFOLD DESIGN AND CONSTRUCTS
#38PCSK9 endonuclease variants, compositions, and methods of use
#39Dual Targeting siRNA Agents
#40Modulators of PCSK9 expression
#41EXPRESSION AND LARGE-SCALE PRODUCTION OF PEPTIDES
#42ANTIBODIES THAT BIND NOVEL PCSK9 VARIANTS
#43METHODS AND PHARMACEUTICAL COMPOSITIONS FOR MODULATING STEM CELLS PROLIFERATION OR DIFFERENTIATION
#44INHIBITION OF PCSK9 THROUGH RNAI
#45Long-acting PCSK9-specific binding protein and application thereof
#46METHODS FOR INCREASING EFFICACY OF LIPID FORMULATED siRNA
#47Anti-PCSK9 antibodies
#48Composition comprising PCSK9 peptide conjugated to a Qbeta carrier and methods of using the same
#49Multivalent heteromultimer scaffold design and constructs
#50PCSK9 VACCINE
#51KEXIN-DERIVED VACCINES TO PREVENT OR TREAT FUNGAL INFECTIONS
#52Application of PCSK9 inhibitors in the preparation of drugs for the treatment of inflammatory immune diseases
#53Peptide vaccines usable for hypercholesterolemia related diseases
#54Dual Targeting siRNA Agents
#55METHOD FOR PREPARATION OF A RECOMBINANT PROTEIN FROM A PRECUSOR
#56Peptides derived from human PCSK9 catalytic domain and uses thereof for promoting LDL-R activity
#57LYSOSOMAL TARGETING AND USES THEREOF
#58PCSK9 peptide vaccine conjugated to a Qbeta carrier and methods of using the same
#59Multivalent heteromultimer scaffold design and constructs
#60KEXIN-DERIVED VACCINES TO PREVENT OR TREAT FUNGAL INFECTIONS
#61Inhibition of PCSK9 through RNAI
#62Treatments using a peptide and/or vaccine
#63PCSK9 vaccine
#64Anti-PCSK9 antibodies
#65Peptide vaccines against PCSK9
#66ANTIBODIES THAT BIND NOVEL PCSK9 VARIANTS
#67Dual Targeting siRNA Agents
#68PCSK9 peptide combination vaccine and method of use
#69Methods for increasing efficacy of lipid formulated siRNA
#70Host cells and methods of use
#71Vaccine capable of inducing formation of antibodies directed to proprotein convertase subtilisin/kexin type 9 (PCSK9) in vivo
#72Process of expressing a fully folded functional two chain insulin glargine
#73PCSK9 vaccine
#74Kexin-derived vaccines to prevent or treat fungal infections
#75Inhibition of PCSK9 through RNAi
#76Dual targeting siRNA agents
#77POLYNUCLEOTIDES ENCODING NOVEL PCSK9 VARIANTS
#78Kexin-Derived Vaccines to Prevent or Treat Fungal Infections
#79Multivalent heteromultimer scaffold design and constructs
#80Methods for increasing efficacy of lipid formulated siRNA
#81Polynucleotides encoding novel PCSK9 variants
#82Antisense oligomers targeting PCSK9
#83RNA INTERFERENCE MEDIATED INHIBITION OF PROPROTEIN CONVERTASE SUBTILISIN KEXIN 9 (PCSK9) GENE EXPRESSION USING SHORT INTERFERING NUCLEIC ACID (siNA)
#84Neutralizing proprotein convertase subtilisin kexin type 9 (PCSK9) variants and uses thereof
#85Polynucleotides encoding novel PCSK9 variants
#86High affinity human antibodies to PCSK9
#87PCSK9 vaccine
#88High affinity human antibodies to PCSK9
#89PCSK9 polypeptides
#90Polynucleotides encoding novel PCSK9 variants
#91Kexin-based vaccines to prevent or treat fungal infections