121412 ⎘
Methods of creating libraries, e.g. combinatorial synthesis Biochemical methods, e.g. using enzymes or whole viable microorganisms
Method of discovering specific functional antibodies
#302Oligonucleotide replacement for di-tagged and directional libraries
#303Rationally designed, synthetic antibody libraries and uses therefor
#304Modified peptide display
#305Rationally designed, synthetic antibody libraries and uses therefor
#306CONSTRUCTION METHOD FOR SERIAL SEQUENCING LIBRARIES OF RAD TAGS
#307Frequency-based modulation of diverse species in a nucleic acid library
#308Methods of transcription activator like effector assembly
#309METHODS FOR SELECTING ENZYMES HAVING PROTEASE ACTIVITY
#310MRNA display antibody library and methods
#311Methods for raising antibodies
#312Targeted in situ protein diversification by site directed DNA cleavage and repair
#313Method For In Vivo High-Throughput Evaluating Of RNA-Guided Nuclease Activity
#314Method for generating a stranded RNA library
#315Methods and Compositions for the Single Tube Preparation of Sequencing Libraries Using Cas9
#316METHOD FOR APTAMER PAIR SELECTION
#317Modifying bacteriophage
#318Compositions and methods for immune repertoire sequencing
#319Sequencing library, and preparation and use thereof
#320Episomal plasmid vectors
#321Methods of sample preparation
#322Scaffolded nucleic acid polymer particles and methods of making and using
#323Methods for sample preparation
#324Cloning and expression system for T-cell receptors
#325Surface, anchored FC-bait antibody display system
#326Measurement and comparison of immune diversity by high-throughput sequencing
#327Method of preparing cell free nucleic acid molecules by in situ amplification
#328Method for constructing next-generation sequencing library for detection of lowfrequency mutation and kit thereof
#329System and methods for massively parallel analysis of nucleic acids in single cells
#330Amplification and analysis of selected targets on solid supports
#331Library preparation methods and compositions and uses therefor
#332Antibody libraries
#333Simultaneous, integrated selection and evolution of antibody/protein performance and expression in production hosts
#334Method and kit for generating high affinity binding agents
#335COMPOSITIONS AND METHODS FOR ACCURATELY IDENTIFYING MUTATIONS
#336COMPOSITIONS AND METHODS FOR ACCURATELY IDENTIFYING MUTATIONS
#337GENERATION OF LIBRARY OF SOLUBLE RANDOM POLYPEPTIDES LINKED TO mRNA
#338Next-generation sequencing libraries
#339Yeast display systems
#340Generation of a cancer-specific immune response toward MUC1 and cancer specific MUC1 antibodies
#341Fibronectin type III domain based scaffold compositions, methods and uses
#342Synthetic single domain antibody
#343Compositions and methods for improving sample identification in indexed nucleic acid libraries
#344Use of heterologous expressed polyketide synthase and small molecule foldases to make aromatic and cyclic compounds
#345Method for constructing high-resolution single cell Hi-C library with a lot of information
#346Method for fragmenting double-stranded RNA and use of the same
#347Full interrogation of nuclease DSBs and sequencing (FIND-seq)
#348Cell analysis device, apparatus, and cell analysis method using same
#349Systems and methods for massively parallel combinatorial analysis of single cells
#350Libraries of genetic packages comprising novel HC CDR3 designs
#351Methods for studying nucleic acids
#352Multiplexed binary assembly and quantitative tracking of bacterial populations
#353Antibody screening methods
#354SEQUENCING LIBRARY PREPARATION IN SMALL WELL FORMAT
#355Methods for high efficiency library preparation using double-stranded adapters
#356Compositions and methods for immune repertoire sequencing
#357SYSTEM AND METHOD FOR GENERATING ANTIBODY LIBRARIES
#358METHOD FOR CONSTRUCTING LONG FRAGMENT DNA LIBRARY
#359RNA-mediated gene assembly from DNA oligonucleotides
#360SCAFFOLDED NUCLEIC ACID POLYMER PARTICLES AND METHODS OF MAKING AND USING
#361Peptide library constructing method and related vectors
#362Generation of binding molecules
#363Fibronectin type III repeat based protein scaffolds with alternative binding surfaces
#364Use of lambda-gam protein in ribosomal display technology
#365Method and system for fragment assembly and sequence identification
#366A METHOD OF SITE-DIRECTED INSERTION TO H11 LOCUS IN PIGS BY USING SITE-DIRECTED CUTTING SYSTEM
#367Immuno-PETE
#368Methods and devices for amplification of nucleic acid
#369Method for constructing nucleic acid single-stranded cyclic library and reagents thereof
#370Transposon nucleic acids comprising a calibration sequence for DNA sequencing
#371Methods for producing optimised therapeutic molecules
#372Methods of constructing libraries comprising displayed and/or expressed members of a diverse family of peptides, polypeptides or proteins and the novel libraries
#373Vesicular linker and uses thereof in nucleic acid library construction and sequencing
#374Genetic encoding of chemical post-translational modification for phage-displayed libraries
#375Method and reagent for constructing nucleic acid double-linker single-strand cyclical library
#376Methods for modulating ATRX-dependent gene repression
#377SYSTEMS AND METHODS FOR AMPLIFICATION AND PHAGE DISPLAY
#378Gene expression analysis ME1HOD using two dimensional cDNA library
#379Primer for nucleic acid random fragmentation and nucleic acid random fragmentation method
#380Enzymatic encoding methods for efficient synthesis of large libraries
#381Error detection in sequence tag directed subassemblies of short sequencing reads
#382Recombinant fusion proteins and libraries from immune cell repertoires
#383Recombinant fusion proteins and libraries from immune cell repertoires
#384Linker element and method of using same to construct sequencing library
#385Method for constructing a sequencing library based on a single-stranded DNA molecule and application thereof
#386Method and system for screening nanobody
#387Collection and methods for its use
#388Multivalent phage display systems and methods
#389Methods for the production of libraries for directed evolution
#390Protein and peptide libraries
#391Mutant viral capsid libraries and related systems and methods
#392System and methods for massively parallel analysis of nucleic acids in single cells
#393Methods and compositions for preparing sequencing libraries
#394Fab fragment libraries and methods for their use
#395Oligonucleic acid variant libraries and synthesis thereof
#396Yeast display systems
#397Full interrogation of nuclease DSBs and sequencing (find-seq)
#398Locus specific amplification using array probes
#399Reducing adapter dimer formation
#400Continuous directed evolution
#401Methods of creating and screening DNA-encoded libraries
#402Recombinant fusion proteins and libraries from immune cell repertoires
#403Recombinant fusion proteins and libraries from immune cell repertoires
#404Negative selection and stringency modulation in continuous evolution systems
#405Measurement and comparison of immune diversity by high-throughput sequencing
#406System and methods for massively parallel analysis of nucleic acids in single cells
#407Compositions and methods for accurately identifying mutations
#408Methods for detecting modification resistant nucleic acids
#409Methods of transcription activator like effector assembly
#410Antigen-binding molecules, the antigen-binding activity of which varies according to the concentration of compounds, and libraries of said molecules
#411Methods for the production of libraries for directed evolution
#412Method for producing antigen-binding molecule using modified helper phage
#413Antibody libraries
#414Sequence tag directed subassembly of short sequencing reads into long sequencing reads
#415Synthetic single domain antibody
#416Compositions and methods for enrichment of nucleic acids
#417Generation of a cancer-specific immune response toward MUC1 and cancer specific MUC1 antibodies
#418Phage displaying system expressing single chain antibody
#419Efficient method for displaying protein multimer
#420Molecular identity tags and uses thereof in identifying intermolecular ligation products
#421Devices and methods for display of encoded peptides, polypeptides, and proteins on DNA
#422Oligonucleotide replacement for di-tagged and directional libraries
#423Use of LAMBDA-GAM protein in ribosomal display technology
#424Transposon nucleic acids comprising a calibration sequence for DNA sequencing
#425Structured peptide processing
#426Fibronectin type III repeat based protein scaffolds with alternative binding surfaces
#427Fibronectin type III domain based scaffold compositions, methods and uses
#428Methods for the production of libraries for directed evolution
#429Polynucleotide modification on solid support
#430Generation of library of soluble random polypeptides linked to mRNA
#431Method of nucleic acid fragmentation
#432Construction of pool of interfering nucleic acids covering entire RNA target sequence and related compositions
#433Measurement and comparison of immune diversity by high-throughput sequencing
#434Surface display of recombinant proteins in lower eukaryotes
#435Methods and compositions
#436Next-generation sequencing libraries
#437Compositions and methods for accurately identifying mutations
#438Simultaneous, integrated selection and evolution of antibody/protein performance and expression in production hosts
#439Amplification and analysis of selected targets on solid supports
#440Constructing method of high-throughput sequencing library and use thereof
#441Methods for cell-free protein synthesis
#442High throughput methylation detection method
#443Methods and devices for amplification of nucleic acid
#444Protein and peptide libraries
#445Connector compound peptide phage display
#446Methods of generating libraries and uses thereof
#447Collection and methods for its use
#448Multispecific peptides
#449Adaptive immunity profiling and methods for generation of monoclonal antibodies
#450Scaffolded nucleic acid polymer particles and methods of making and using
#451Methods of generating libraries and uses thereof
#452Oligonucleotide replacement for di-tagged and directional libraries
#453Reducing adapter dimer formation
#454Peptide library production method, peptide library, and screening method
#455Continuous directed evolution
#456Phage displaying system expressing single chain antibody
#457Antibody preparation method, and antibody and antibody library thus prepared
#458Efficient method for displaying protein multimer
#459DNA library, preparation method thereof, and device for detecting SNPs
#460Methods for detecting modification resistant nucleic acids
#461RNA-mediated gene assembly from DNA oligonucleotides
#462Systems and methods for amplification and phage display
#463Modified peptide display
#464Measurement and comparison of immune diversity by high-throughput sequencing
#465Method for constructing libraries of non-standard peptide compounds comprising N-methyl amino acids and other special (non-standard) amino acids and method for searching and identifying active species
#466Sequence tag directed subassembly of short sequencing reads into long sequencing reads
#467Error detection in sequence tag directed subassemblies of short sequencing reads
#468Methods for manufacturing molecular arrays
#469Microfabrication methods for the optimal patterning of substrates
#470Methods for manufacturing molecular arrays
#471Fibronectin type III domain based scaffold compositions, methods and uses
#472Systems and methods for processing fluids
#473Fibronectin type III repeat based protein scaffolds with alternative binding surfaces
#474Methods of constructing libraries comprising displayed and/or expressed members of a diverse family of peptides, polypeptides or proteins and the novel libraries
#475Transposon nucleic acids comprising a calibration sequence for DNA sequencing
#476Protein display
#477COMPOSITIONS AND METHODS FOR THE RAPID BIOSYNTHESIS AND IN VIVO SCREENING OF BIOLOGICALLY RELEVANT PEPTIDES
#478High affinity adaptor molecules for redirecting antibody specifity
#479DONOR SPECIFIC ANTIBODY LIBRARIES
#480METHODS OF GENERATING IMPROVED ANTIGEN-BINDING AGENTS USING CHAIN SHUFFLING AND OPTIONALLY SOMATIC HYPERMUTATION
#481Compositions and methods for the assembly of polynucleotides
#482GENE EXPRESSION ANALYSIS METHOD USING TWO DIMENSIONAL cDNA LIBRARY
#483Simultaneous, integrated selection and evolution of antibody/protein performance and expression in production hosts
#484RATIONAL LIBRARY
#485Multivalent phage display systems and methods
#486ISOLATING BIOLOGICAL MODULATORS FROM BIODIVERSE GENE FRAGMENT LIBRARIES
#487RAPID DISPLAY METHOD IN TRANSLATIONAL SYNTHESIS OF PEPTIDE
#488COMBINATORIAL METHODS FOR OPTIMIZING ENGINEERED MICROORGANISM FUNCTION
#489ENGINEERING OF ZINC FINGER ARRAYS BY CONTEXT-DEPENDENT ASSEMBLY
#490Simultaneous, integrated selection and evolution of antibody/protein performance and expression in production hosts
#491Structured peptide processing
#492METHODS AND KITS TO GENERATE miRNA- AND SMALL RNA-EXPRESSING VECTORS, AND ITS APPLICATION TO DEVELOP LENTIVIRAL EXPRESSION LIBRARIES
#493Reducing adapter dimer formation
#494Multispecific peptides
#495STRUCTURED POLYCYCLIC PEPTIDE
#496COMBINATORIAL LIBRARIES OF PROTEINS HAVING THE SCAFFOLD STRUCTURE OF C-TYPE LECTIN-LIKE DOMAINS
#497Particle Population and Methods of Making and Using
#498Collection and methods for its use
#499Vector for inhibition-based high-throughput screen strategy
#500Methods of creating and screening DNA-encoded libraries
#501Method for producing second-generation library
#502SOMATIC HYPERMUTATION SYSTEMS
#503Method of creating a library of bacterial clones with varying levels of gene expression
#504Adaptive immunity profiling and methods for generation of monoclonal antibodies
#505Methods of Generating Gene Specific Libraries
#506METHODS AND COMPOSITIONS FOR POLYPEPTIDE ENGINEERING
#507Triple tag sequences and methods of use thereof
#508Method for constructing mutagenesis libraries in situ
#509Methods and compositions for polynucleotide library production, immortalization and region of interest extraction
#510Method for screening phage display libraries against each other
#511Methods of generating libraries and uses thereof
#512Expression system for modulating an immune response
#513Yeast Display Systems
#514Amplification and analysis of selected targets on solid supports
#515Screening method and vector, vector library, and assay kit used therefor
#516Production Of Single-Stranded Circular Nucleic Acid
#517βGI-IgG intron for enhanced anti-IGF1R expression
#518METHOD FOR PRODUCTION OF cDNA LIBRARY HAVING REDUCED CONTENT OF cDNA CLONE DERIVED FROM HIGHLY EXPRESSED GENE
#519Particle Arrays and Methods of Making and Using
#520Methods of Using Porous Particles
#521Methods of Primer Extension Using Porous Particle Supports
#522Methods of Making Libraries of Nucleic Acids Using Porous Particles
#523Scaffolded Nucleic Acid Polymer Particles and Methods of Making and Using
#524Scaffolded Nucleic Acid Polymer Particles and Methods of Making and Using
#525METHOD OF NUCLEIC ACID DELIVERY INTO THREE-DIMENSIONAL CELL CULTURE ARRAYS
#526SOMATIC HYPERMUTATION SYSTEMS
#527Inhibition-based high-throughput screen strategy for cell clones
#528Synthetic polypeptide libraries and methods for generating naturally diversified polypeptide variants
#529Libraries of genetic packages comprising novel HC CDR3 designs
#530MICROFABRICATION METHODS FOR THE OPTIMAL PATTERNING OF SUBSTRATES
#531ISOLATING BIOLOGICAL MODULATORS FROM BIODIVERSE GENE FRAGMENT LIBRARIES
#532Combinatorial Libraries Based on C-type Lectin-like Domain
#533REDUCED CODON MUTAGENESIS
#534PHAGE DISPLAYING SYSTEM EXPRESSING SINGLE CHAIN ANTIBODY
#535Synthetic polypeptide libraries and methods for generating naturally diversified polypeptide variants
#536METHODS AND COMPOSITIONS FOR POLYPEPTIDE ENGINEERING
#537VIRAL RECOMBINEERING AND USES THEREOF
#538Multiplex barcoded Paired-End ditag (mbPED) library construction for ultra high throughput sequencing
#539Methods for Identifying One or More Bioactive Genes
#540Surface display of recombinant proteins in lower eukaryotes
#541Methods and compositions
#542INHIBITION-BASED HIGH-THROUGHPUT SCREEN STRATEGY FOR CELL CLONES
#543Scaffolded nucleic acid polymer particles and methods of making and using
#544Providing improved immunoglobulin sequences by mutating CDR and/or FR positions
#545DONOR SPECIFIC ANTIBODY LIBRARIES
#546Method of preparing libraries of template polynucleotides
#547Fibronectin type III domain based scaffold compositions, methods and uses
#548Identification of peptide tags for the production of insoluble peptides by sequence scanning
#549ISOLATING BIOLOGICAL MODULATORS FROM BIODIVERSE GENE FRAGMENT LIBRARIES
#550Methods for generating polynucleotides having desired characteristics by iterative selection and recombination
#551Fibronectin type III domain based scaffold compositions, methods and uses
#552NOVEL PROTEINS WITH TARGETED BINDING
#553Methods and compositions for identifying binding partners from libraries of biomolecules
#554Protein scaffolds and uses thereof
#555Methods and compounds for phototransfer
#556Methods for the formation of disulphide bonds
#557Triple tag sequence and methods of use thereof
#558Compositions and methods for the assembly of polynucleotides
#559Compositions and methods for the assembly of polynucleotides
#560Methods for detecting modification resistant nucleic acids
#561Generation of library of soluble random polypeptides linked to mRNA
#562Antibody libraries
#563Combined automated parallel synthesis of polynucleotide variants
#564Metagenomic Functional Selection
#565Methods for creating diversity in libraries and libraries, display vectors and methods, and displayed molecules
#566Sequence tag directed subassembly of short sequencing reads into long sequencing reads
#567Rationally designed, synthetic antibody libraries and uses therefor
#568Generation of a cancer-specific immune response toward MUC1 and cancer specific MUC1 antibodies
#569shRNA library
#570Trace mRNA amplification method and use thereof
#571METHOD OF SYNTHESIZING POLYNUCLEOTIDE VARIANTS
#572Enzymatic encoding methods for efficient synthesis of large libraries
#573Methods for enriching subpopulations
#574FOCUSED LIBRARY GENERATION
#575Methods and devices for amplification of nucleic acid
#576Rationally designed, synthetic antibody libraries and uses therefor
#577Methods of constructing libraries comprising displayed and/or expressed members of a diverse family of peptides, polypeptides or proteins and the novel libraries
#578Methods and compositions for polypeptide engineering
#579Method for manufacturing recombinant polyclonal proteins
#580Locus specific amplification using array probes
#581Construction of pool of interfering nucleic acids covering entire RNA target sequence and related compositions
#582Methods of generating libraries and uses thereof
#583Somatic hypermutation systems
#584Monoclonal antibodies that specifically bind to and neutralize toxin, compositions, and methods of use
#585METHODS FOR GENERATING POLYNUCLEOTIDES HAVING DESIRED CHARACTERISTICS BY ITERATIVE SELECTION AND RECOMBINATION
#586Mutant reverse transcriptase and methods of use
#587Donor specific antibody libraries
#588Isolating biological modulators from biodiverse gene fragment libraries
#589Oil-immersion, soft-print array replication
#590Arrayed polynucleotides
#591NOVEL FAB FRAGMENT LIBRARIES AND METHODS FOR THEIR USE
#592Cellular Arrays
#593Method of creating a library of bacterial clones with varying levels of gene expression
#594Passaged neural stem cell-derived neuronal networks as sensing elements for detection of environmental threats
#595Method to prepare macrolide analogs
#596Combinatorial libraries of proteins having the scaffold structure of C-type lectin-like domains
#597Method of preparing libraries of template polynucleotides
#598Amplification and analysis of whole genome and whole transcriptome libraries generated by a DNA polymerization process
#599Methods and compositions for polypeptide engineering
#600Method for producing second-generation library