170784 ⎘
Screening for compounds of potential therapeutic value Screening involving studying the effect of compounds C on the interaction between interacting molecules A and B (e.g. A = enzyme and B = substrate for A, or A = receptor and B = ligand for the receptor)
INTERACTION OF BIM WITH TRIM2, AN E3 UBIQUITIN LIGASE
#1202HIFαprolyl hydroxylation assay
#1203Method for quantitative analysis of interactions between HIF-1alpha C-terminal peptides and CBP or p300 proteins and method of screening inhibitors using the same
#1204Biased Ligands for Receptors Such as the PTH Receptor
#1205Parkin substrate and assay
#1206Assays and methods for determining STIM2 activity
#1207Methods for determining GTP cyclohydrolase I or II activity
#1208Antiviral screening method to identify inhibitors of phosphatidylinositol 4,5-bisphosphate [PI(4,5)P] binding to the HIV gag matrix (MA) protein
#1209Compositions and Methods for Identifying Substrate Specificity of Inhibitors of Gamma Secretase
#1210Methods of modulating cell death based on the Bit-1/AES regulatory pathway
#1211Identification of modulators of serine protease inhibitor Kazal and their use as anti-cancer and anti-viral agents
#1212EGFR ANTIGEN-BINDING MOLECULES AND USES THEREOF
#1213Plasminogen activator inhibitor-1 inhibitors and methods of use thereof to modulate lipid metabolism
#1214Mapkap kinase-2 as a specific target for blocking proliferation of P53-defective cells
#1215METHODS AND COMPOSITIONS FOR AFFECTING CYCLOPHILIN A REGULATION OF KINASES IN MODULATING CELLULAR ACTIVITIES
#1216Organic Compounds
#1217Methods of modulating tubulin deacetylast activity
#1218Method of quantifying the G protein-coupled receptor (GPCR)/G protein coupling using a cell membrane array
#1219Expression of human milk proteins in transgenic plants
#1220Fluorescent Labeled Sphingosines
#1221Modulation of Muci-Dependent Anti-Estrogen Resistance
#1222Methods and compositions for the detection and isolation of ligands
#1223Three-dimensional structures of TALL-1 and its cognate receptors and modified proteins and methods related thereto
#1224Method For Treating Huntington's Disease by Inhibiting Dephosphorylation of Huntingtin at S421
#1225Anti-fugetactic agents for the treatment of ovarian cancer
#1226Substrates and assays for beta-secretase activity
#1227Assays for modulators of parkin activity using S5a as a parkin substrate
#1228Methods for assessing CDK5 activation and function
#1229Compositions and methods for identifying response targets and treating flavivirus infection responses
#1230Means and methods for the determination of camp in vitro and in vivo
#1231Screening method
#1232Selective and dual-action p53/MDM2/MDM4 antagonists
#1233Devices and methods for profiling enzyme substrates
#1234G protein coupled receptor signaling modulation
#1235Compositions and methods for gene expression
#1236Novel Therapeutic Molecular Variants And Uses Thereof
#1237Method, composition and kit for antigenic binding of norwalk-like viruses
#1238Method of Assaying Fad Synthetase
#1239Assay of Ubiquitinization of Synoviolin and Use Thereof in Screening
#1240THIOFLAVIN T METHOD FOR DETECTION OF AMYLOID POLYPEPTIDE FIBRIL AGGREGATION
#1241YEAST CELLS EXPRESSING MODIFIED G PROTEINS AND METHODS OF USE THEREFOR
#1242Use of specific T2R receptors to identify compounds that block bitter taste
#1243Method
#1244FGF21 upregulates expression of GLUT-1 in a βklotho-dependent manner
#1245Polynucleotides encoding acetylcholine-gated chloride channel subunits of
#1246SPECIFIC BINDING AGENTS FOR KSHV vIL-6 THAT NEUTRALIZE A BIOLOGICAL ACTIVITY
#1247Claudin polypeptides
#1248Connective Tissue Growth Factor Signaling
#1249Enhancement of vanadium-containing phosphatase inhibitors
#1250Ubiquitin E3 ligase
#1251Neuropilin/VEGF-C/VEGFR-3 Materials and Methods
#1252METHODS AND COMPOSITIONS FOR MODULATING IL-17F/IL-17A BIOLOGICAL ACTIVITY
#1253ANTAGONIZING INTERLEUKIN-21 RECEPTOR ACTIVITY
#1254IL-1F6 polypeptides
#1255Compositions and methods for increasing bone mineralization
#1256Methods for Identifying Compounds that Modulate Enzymatic Activities by Employing Covalently Bonded Target-Extender Complexes with Ligand Candidates
#1257Use of Eph Receptor Inhibitors for the Treatment of Neurodegenerative Diseases
#1258Method of identifying compounds useful to treat neuronal degenerative diseases
#1259Agent for treating allergic or hypersensitivity condition
#1260Constrained Hiv V3 Loop Peptides as Novel Immunogens and Receptor Antagonists
#12612031 Oxidoreductase
#1262Dephosphorylation of HDAC7 By Myosin Phosphatase
#1263Modulation of T cell signaling threshold and T cell sensitivity to antigens
#1264Nucleic acids encoding the GPCR, RUP3, and methods of use thereof
#1265Env polypeptide complexes and methods of use
#1266Regulation and function of TPL-2
#1267Enzyme Inhibitors and Uses Thereof
#1268Tumor Suppressor Lkb1 Kinase Directly Activates Amp-Activated Kinase
#1269Compositions and methods for regulation of calcium-dependent signaling in brain
#1270Inducible Nitric Oxide Synthase Binds, S-Nitrosylates, and Activates Cyclooxygenase-2
#1271Assay for cytochrome P450 isoform 2C9
#1272Cardiovascular safety assay
#1273Methods of diagnosis of spinal muscular atrophy and treatments thereof
#1274Reducing myelin-mediated inhibition of axon regeneration
#1275Identification of bitter ligands that specifically activate human T2R receptors and related assays for identifying human bitter taste modulators
#1276Core 2 glcnac-t inhibitors
#1277Compositions and methods for increasing bone mineralization
#1278Method for modulating cell proliferation
#1279Screening assays for binding antagonists of the AMD-associated variant of factor H (H384)
#1280Screening assays for hedgehog agonists and antagonists
#1281Disheveled PDZ modulators
#1282MATERIALS AND METHODS TO INHIBIT HODGKIN AND REED STERNBERG CELL GROWTH
#1283Cell-based assays employing voltage and calcium dyes
#1284PDZ DOMAIN INTERACTIONS AND LIPID RAFTS
#1285Methods of screening compounds inhibiting signal transduction through inflammatory cytokines
#1286Novel Screening Method
#1287METHOD FOR INHIBITING CELLULAR ACTIVATION BY INSULIN-LIKE GROWTH FACTOR-1
#1288METHOD OF TREATING SIDE EFFECTS INDUCED BY THERAPEUTIC AGENTS
#1289Method for screening for compounds using MHC class II invariant chain polypeptide and macrophage migration inhibitory factor
#1290Methods for modulating the sensation of satiety perception and agents useful for same
#1291Stresscopins and their uses
#1292Compositions and Methods for Assaying hERG Channel Binding
#1293Identification and characterization of novel proline racemases and hydroxyproline-2-epimerases, uses thereof, and methods of identifying proline racemases and hydroxyproline-2-epimerases
#1294Nucleic acids encoding monomers of a type II serine proteinase inhibitor
#1295Use of methionine synthase inhibitors for the treatment of fungal diseases of crops
#1296Preventing and reversing the formation of advance glycosylation endproducts
#1297Method for Identifying Inhibitors Using a Homology Model of Polo-Like Kinase 1
#1298SHC proteins as therapeutic targets in proliferative diseases
#1299Screening assay using G-protein coupled receptor protein OT7T175
#1300Optical molecular sensors for cytochrome P450 activity
#1301Agents for treatment of HCV and methods of use
#1302Method of screening compound preventing cells from infection with Hepatitis C virus (HCV)
#1303Compositions comprising a ligand of chemerinR
#1304Methods of diagnosing cervical cancer
#1305Molecules and methods for inhibiting shedding of KIM-1
#1306Method for diagnosing non-small cell lung cancers by tRNA-dihydrouridine synthase activity of
#1307Compositions and methods for regulating peptidyltransferase activity and uses thereof
#1308NOVEL GERMINAL KINASE PROTEINS, COMPOSITIONS AND METHODS OF USE
#1309MUC1 and ABL
#1310Method of screening for inhibitors of tau protein phosphororylation by tyrosine kinase c-Abl
#1311Dendritic cell transmembrane serine protease
#1312Assays for detecting modulators of cytoskeletal function
#1313Nucleic acid molecules encoding emission ratiometric indicators of phosphoinositides
#1314Devices and methods for profiling enzyme substrates
#1315Substrates and Assays for Beta Secretase Activity
#1316ActRIIB Fusion Polypeptides and Uses Therefor
#1317METHOD FOR SCREENING TRANSCRIPTIONAL COREGULATORY PROTEINS OF TRANSCRIPTION FACTORS, AND ANDROGEN RECEPTOR TRANSCRIPTIONAL COREGULATORY PROTEINS AS TARGETS FOR ANDROGEN RECEPTOR-DEPENDENT DISEASES
#1318ASSAYS FOR IDENTIFYING UBIQUITIN AGENTS AND FOR IDENTIFYING AGENTS THAT MODIFY THE ACTIVITY OF UBIQUITIN AGENTS
#1319Compositions and methods for detecting and treating HIV infections
#1320Method for selecting allosteric regulators of class III G protein-coupled receptors
#1321Assays and kits for detecting protein binding
#1322Method of analyzing protein structural affinity relationship
#1323Receptor for GDNF family ligands
#1324Identification of substances that inhibit NEMO oligomerization
#1325Expression of human milk proteins in transgenic plants
#1326Compositions for Inhibiting plexin-A1-DAP12 interactions and Methods of Treating Inflammatory, Autoimmune or Bone Resorption Diseases Using the Same
#1327Noble metal complex-mediated immunosuppression
#1328Methods for identifying modulators of RGS21 activity, compositions comprising an RGS21 Modulator, and methods of use thereof to modulate taste sensation
#1329CRAC channel and modulator screening methods
#1330FLAVIVIRUS PROTEASE SUBSTRATES AND INHIBITORS
#1331USE OF CORE 2 GlcNAc TRANSFERASE INHIBITORS IN TREATING INFLAMMATION
#1332Methods for identifying chemical modulators of Ras superfamily GTPase activity
#1333Phosphorylated COP1 molecules and uses thereof
#1334Treatment of atherosclerosis
#1335Method for treating an immune disorder by decreasing NIK-SIVA complex formation
#1336COP1 molecules and uses thereof
#1337Methods for preventing or reducing ischemia/reperfusion induced myocardial cell death
#1338PROTEIN KINASE REGULATION
#1339Assays for identifying ubiquitin agents and for identifying agents that modify the activity of ubiquitin agents
#1340Method for Inhibiting Telomerase Activity and an Agent for Inhibiting the Same
#1341Antibacterial agents and methods of identifying and utilizing same
#1342SULFOTYROSINE SPECIFIC ANTIBODIES AND USES THEREFOR
#1343Identification of Phospholipase A2 as Target in Cancer Treatment, with Special Emphasis on Colorectal Cancer and Its Mechanism of Action
#1344Bacterial iron acquisition targets
#1345Methods of identifying compounds for producing insulin sensitization
#1346Method for expressing a functional membrane-bound receptor protein using budded baculovirus
#1347Protein kinase C iota
#1348Methods and Compositions for Modulating Satiety
#1349Screening systems utilizing RTP801
#1350Tie Receptor and Tie Ligand Materials and Methods for Modulating Female Fertility
#1351Compositions and methods for the treatment and diagnosis of neoplastic and infectious diseases
#1352Methods Of Treating Demyelinating Disorders
#1353Chondroitin sulfate binding proteins and modulators thereof
#1354Mutant IGFBP-3 molecules that do not bind to IGFS, but retain their ability to functionally bind IGFBP-3 receptor
#1355Assay for inositol phosphorylceramide synthase activity
#1356METHOD OF IDENTIFYING COMPOUNDS USEFUL TO TREAT NEURONAL DEGENERATIVE DISEASES
#1357Methods to improve creatine kinase metabolism and contractile function in cardiac muscle for the treatment of heart failure
#1358Methods for identifying polypeptide targets and uses thereof for treating immunological diseases
#1359Modulation of activity of neurotrophins
#1360Interaction of Colon Cancer Related Gene C200RF20 With P120
#1361COMPOSITIONS AND METHODS FOR TREATING INFLAMMATORY DISORDERS
#1362Single-molecule platform for drug discovery: methods and apparatuses for drug discovery, including discovery of anticancer and antiviral agents
#1363Bcma Polypeptides and Uses Thereof
#1364High-throughput screening method for intergrin antagonist and new peptide screened therefrom
#1365Methods to treat or prevent hormone-resistant prostate cancer using siRNA specific for protocadherin-PC, or other inhibitors of protocadherin-PC expression or activity
#1366Method for Identifying and Producing Effectors of Calmodulin-Dependent Peptidyl-Prolyl Cis/Trans Isomers
#1367Modulators of ATP-binding cassette transporters
#1368Specific binding agents for KSHV vIL-6 that neutralize a biological activity
#1369Functional antibodies that specifically bind to the Chemerin receptor
#1370Compositions and methods for treating diseases associated with T-box and N-Myc
#1371Method for identifying inhibitors of G protein coupled receptor signaling
#1372Methods for screening agents that modulate presenilin activity and A-β production
#1373Screening Assay and Treatment
#1374Pyrrolo[1,2b]pyridazine compounds and their uses
#1375Detection of influenza virus
#1376Covalently stabilized chimeric coiled-coil HIV gp41 N-peptides with improved antiviral activity
#1377Neuregulin variants and methods of screening and using thereof
#1378Hepatitis C virus NS2/3 activity assay
#1379Methods and compositions for exotoxins
#1380Integrase-dirived HIV-inhibiting agents
#1381Hydrolases, nucleic acids encoding them and methods for making and using them
#1382TGFBeta
#1383NOVEL PEROXIREDOXIN DEFENSE SYSTEM FROM MYCOBACTERIUM TUBERCULOSIS
#1384Method of diagnosis of obesity
#1385Pain signaling molecules
#1386Materials and methods for identifying agents that modulate Norrin, Norrin mimetics, and agents identified thereby
#1387Inhibitors of 2-oxoglutarate dioxygenase as gamma globin inducers
#1388Method of cancer treatment by p53 protein control
#1389Assays for detection of bioactive compounds that interact with heat shock protein 90
#1390Screening assay for modulators of interaction between interleukin-12 and/or -23 with their receptors
#1391Cell-based assay for G-protein-coupled receptor-mediated activity employing a mutated cyclic nucleotide-gated ion channel and a membrane potential dye
#1392Recombinant platelet collagen receptor glycoprotein VI and its pharmaceutical use
#1393RECOMBINANT PLATELET COLLAGEN RECEPTOR GLYCOPROTEIN VI AND ITS PHARMACEUTICAL USE
#1394IL-1 zeta splice variant polypeptide
#1395Methods and compositions for modulating gamete adhesion
#1396Signal transduction protein TAB2
#1397Methods and compositions for diagnosis and treatment of influenza
#1398Chimeric human sweet-umami and umami-sweet taste receptors
#1399VIRAL PROTEASE
#1400SULFOTYROSINE SPECIFIC ANTIBODIES AND USES THEREFOR
#1401Methods of treatment and uses for CaMKII and its interaction with HDACs and calpain
#1402Pregnancy-associated plasma protein-A2 (PAPP-A2)
#1403IDENTIFICATION OF NON-COVALENT COMPLEXES BY MASS SPECTROMETRY
#1404Control of proliferation and apoptosis in cancer cells
#1405Identification of compounds for inhibiting complexation of C-reactive protein with fibronectin
#1406Interaction inhibitors, method of detecting interaction inhibitor and kit detecting interaction inhibitor
#1407Means for use in treating diseases correlated with or caused by non-physiological levels of microtubule-associated PP2Ac
#1408METHODS AND COMPOSITIONS FOR MODULATING HGF/MET
#1409Systems of diagnosing cervical cancer
#1410Modulation of IL-2 production by T-bet
#1411Identification and characterization of racemases, definition of protein signatures, and a test for detecting D-amino acid and for screening molecules capable of inhibiting the activity of racemase, especially proline racemase
#1412Reagents and method for modulating Dkk-mediated interactions
#1413Method of selecting novel immunosuppressant
#1414Releasable wire connector
#1415Human G protein-coupled receptors
#1416Control of TGFβ signaling by km23 superfamily members
#1417Inhibitor of interaction of granzyme b with golgin-160
#1418Polypeptide complex of TRPM8 and calmodulin and its uses thereof
#1419Compositions and methods for the treatment of cancer
#1420Compositions and methods for identifying modulators of TRPV2
#1421Ion channel
#1422Specific binding sites in collagen for integrins and use thereof
#1423Bak binding protein, DNA encoding the protein, and methods of use thereof
#1424Methods and compositions for treating cervical cancer
#1425Modulation of mesenchymal and metastatic cell growth
#1426Hematopoietic progenitor kinase 1 for modulation of an immune response
#1427VEGF-C or VEGF-D materials and methods for treatment of neuropathologies
#1428Method for reducing HIV viral budding by administering a VPS28-specfic antibody that disrupts Gag-TSG101-VPS28 binding interactions
#1429Method for identifying modulators of G protein coupled receptor signaling
#1430Method of screening compounds
#1431OPTICAL MOLECULAR SENSORS FOR CYTOCHROME P450 ACTIVITY
#1432METHODS AND REAGENTS FOR THE ANALYSIS AND PURIFICATION OF POLYSACCHARIDES
#1433Compounds and methods for the diagnosis and treatment of amyloid associated diseases
#1434METHODS FOR SHP1 MEDIATED NEUROPROTECTION
#1435Agents that modulate the interaction of B7-1 polypeptide with PD-L1 and methods of use thereof
#1436Compositions and methods for inhibiting platelet activation and thrombosis
#1437Shc proteins as therapeutic targets in proliferative diseases
#1438Identification of therapeutic compounds
#1439Methods for selective targeting
#1440Proteinase inhibitor, precursor thereof and genetic sequences encoding same
#1441Methods for assaying inhibition of HIV-1 envelope glycoprotein-mediated membrane fusion
#1442Cell-based luminogenic and nonluminogenic proteasome assays
#1443Vav inhibition in graft rejection
#1444Neuregulin protein regulation of synaptic proteins
#1445Method for detection of MIP-4 and CCRL2 binding and activity modulating agents
#1446Methods and compositions for modulating somatolactogenic functions
#1447Ndr kinase modulators
#1448Method of treatment
#1449Regulation of interaction between rapl and rap1
#1450Inhibitors of amyloid precursor protein processing
#1451Hemiasterlin affinity probes and their uses
#1452Compositions and methods of mutant Nogo-66 domain proteins
#1453Use of antagonists of ghrelin or ghrelin receptor to treat intestinal inflammation
#1454Modulation of HCN channels by second messengers
#1455Preventing and reversing the formation of advance glycosylation endproducts
#1456Heparin compositions and selectin inhibition
#1457Novel treatment
#1458Three-dimensional structures of TALL-1 and its cognate receptors and modified proteins and methods related thereto
#1459Triazolopyrimidine derivatives
#1460Specific binding agents for KSHV vIL-6 that neutralize a biological activity
#1461Methods for detecting virulent , for evaluating virulence, and for screening new drugs employing the 3′UTR of SUB2 and the SUB2 serine protease
#1462Compounds having inhibitive activity of phosphatidylinositol 3-kinase and methods of use thereof
#1463Multiple sclerosis therapy and diagnosis
#1464METHODS FOR SHP1 MEDIATED NEUROPROTECTION
#1465Human tumor necrosis factor TR21 and methods based thereon
#1466Sequence #115 as a target for identifying weight modulating compounds
#1467Compositions and methods for treatment of chronic and infectious diseases
#1468Compositions and methods for treatment of eye disorders
#1469Methods, compositions and compound assays for inhibiting amyloid-beta protein production
#1470Cyclin groove inhibitors
#1471METHODS AND COMPOSITIONS FOR TREATING NEUROLOGICAL DISORDERS
#1472Method of controlling transcription insulin gene
#1473Use of substances inhibiting the association of said protein with ubiquitin c-terminal hydrolase for altering cellular responses to tgf-beta or bmp
#1474Peptide for assaying hERG channel binding
#1475Vaccine compositions for prevention of chronic and infectious diseases
#1476Use of saposin-related proteins for preventing and treating obesity, diabetes and/or metabolic syndrome
#1477Diagnosis and treatment of Alzheimer disease
#1478T cell protein and nucleotides encoding the same
#1479METHOD FOR REDUCING LYSOZYME ENZYMATIC ACTIVITY
#1480Inhibition of nerve cell death by inhibiting degradation of shc3, atf6 or crebl1 by htra2 and method of ameliorating neurodegenerative diseases
#1481Fluorescent probes for use in protein kinase inhibitor binding assay
#1482Diagnostics and therapeutics for diseases associated with dopamine receptor d4 (drd4)
#1483Use of dg931 protein for treating diabetes, obesity and metabolic syndrome
#1484Methods and composition for derepressions of IAP-inhibited caspase
#1485Method of screening for drugs that block ligand binding to a lipid binding protein
#1486Cell lines and host nucleic acid sequences related to infectious disease
#1487Compositions and methods for modulating cells via CD14 and toll-like receptor 4 signaling pathway
#1488Method for identifying a substance which mediates interaction between interleukin 22 and an interleukin 22 receptor
#1489FBL2-specific agents as modulators of Flaviviridae RNA replication
#1490Modulators and modulation of the interaction between RGM and Neogenin
#1491SIR2 activity
#1492Slim compositions and methods of use thereof
#1493Modulation of the synthesis of insulin
#1494Yersinia polypeptide vaccines, antibodies and immunomodulatory proteins
#1495Method for screening transcriptional coregulatory proteins of transcription factors, and androgen receptor transcriptional coregulatory proteins as targets for androgen receptor-dependent diseases
#1496Inducible nitric oxide synthase binds, S-nitrosylates, and activates cyclooxygenase-2
#1497Methods of identifying inhibitors of GTP cyclohydrolase I and II
#1498Mutagenesis of aspergillus fungi and identification of genes essential for growth
#1499Use of dg008,dg065,dg210 or dg239 secreted protein products for preventing and treating pancreatic diseases and/or obesity and/or metabolic syndrome
#1500Methods for modulating neuronal responses