170784 ⎘
Screening for compounds of potential therapeutic value Screening involving studying the effect of compounds C on the interaction between interacting molecules A and B (e.g. A = enzyme and B = substrate for A, or A = receptor and B = ligand for the receptor)
Methods for identifying enzyme inhibitors and protein kinases
#1502Novel mechanism for hiv-1 entry into host cells and peptides inhibiting this mechanism
#1503Novel therapies and methods of screening for therapeutic compounds
#1504Method for treating conditions associated with fear memory
#1505Method using a nonlinear optical technique for detection of interactions involving a conformational change
#1506Novel fibulin-like polypeptides
#1507Protein fragment complementation assays for high-throughput and high-content screening
#1508Modulation of Th2 lineage commitment by T-bet
#1509TEX14 compositions and modulators thereof to alter intercellular bridge development and function
#1510Diagnostic and therapeutic use of a sulfotransferase for neurodegenerative diseases
#1511Chimeric gaba receptor
#1512Compositions and methods for preventing, treating and diagnosing diabetes
#1513Methods for determining plasma free drug concentration by direct measurement of binding affinity of protease inhibitors to plasma proteins
#1514Human T2R receptors for acetaminophen ranitidine, strychnine and denatomium and related assays for identifying human bitter taste modulators
#1515Uses of DC-SIGN and DC-SIGNR for inhibiting hepatitis C virus infection
#1516Methods of treatment using antibodies to Neutrokine-alpha
#1517Fluorescent protein variants and methods for making same
#1518Phosphorylation and regulation of Akt/PKB by the rictor-mTOR complex
#1519Screening assays for cannabinoid-ligand-type modulators of gpr55
#1520Methods of Treatment Using Antibodies to Neutrokine-alpha
#1521Compositions of low molecular weight heparin produced with modified heparinase III
#1522Methods for assessing p19-Arf interactions in cMyc
#1523Methods for preparing low molecular weight heparin with modified heparinase III
#1524Single chain recombinant T cell receptors
#1525Method for Identifying compounds for suppressing metastasizing tumor cells
#1526Compositions and methods for promoting angiogenesis
#1527Purified Stat proteins and methods of purifying thereof
#1528EPF derived peptides and therapeutic compositions
#1529GD2 ligands
#1530Molecules and methods for inhibiting shedding of KIM-1
#1531Novel mucin-like polypeptides
#1532Polypeptides and polypeptide constructs comprising single domain antibodies directed against von Willebrand factor
#1533Method of screening for agents that modulate a homer signaling pathway
#1534Method of screening substance interacting with ABC protein
#1535Assays for fprl-1 ligands
#1536Adherent entities and uses therefor
#1537Methods for assaying inhibition of HIV-1 envelope glycoprotein-mediated membrane fusion
#1538Monoclonal antibody specific for PPAR gamma, hydridoma cell line producing the same, and method for detecting regulator related to diseases, including inflammation, cancer and metabolic diseases, using the same
#1539Method of detection and quantification of cGMP by using a cGMP-visualizing probe
#1540Toll-like receptor 9 modulators
#1541Alternatively spliced isoforms of purinergic receptor P2X, ligand-gated ion channel, subunits 3 and 4 (P2RX3, P2RX4)
#1542Receptor and screening methods
#1543Assays for identifying ubiquitin agents and for identifying agents that modify the activity of ubiquitin agents
#1544Tyrosylprotein sulfotransferases and methods of use thereof
#1545Antigenic binding patterns of norovirus to human histo-blood group antigens
#1546Methods and compositions for treating cellular proliferative diseases
#1547Mammalian cytokines; receptors; related reagents and methods
#1548Metabolism-modulating agents and uses therefor
#1549System for protease mediated protein expression
#1550Fluorescence polarization assay for determining histidine decarboxylase activity
#1551Braca1/acc alpha molecular complexes, diagnostic and therapeutic applications
#1552Novel tumor suppressor gene and compositions and methods for making and using the same
#1553Reducing NgR-p75 mediated inhibition of axon regeneration
#1554Toll-like receptor assays
#1555Modulators of retinol-retinol binding protein (RBP)-transthyretin (TTR) complex formation
#1556Sperm specific lysozyme-like proteins
#1557Isolated physiologically active peptide and use thereof
#1558Method for determining inhibition activity of a compound on one of the enzymes of the folate synthesis pathway
#1559E7 regulation of p21 cip1 through akt
#1560Compositions for manipulating the lifespan and stress response of cells and organisms
#1561Methods and compositions for modulating hepatocyte growth factor activation
#1562Methods and compositions for modulating Bax-mediated apoptosis
#1563CaMKII/calcium channel binding-related compositions and methods
#1564Complex formed by N-linked glycoproteins (SIBLINGS) and Factor H
#1565Ligand for G-protein coupled receptor FPRL2 and uses thereof
#1566Therapeutic agents and methods for cardiovascular disease
#1567Glycoproteins which bind to TNF
#1568Heparinase III and methods of specifically cleaving therewith
#1569Tr4/tr2 response elements
#1570Nuclear factors associated with transcriptional regulation
#1571Histone deacetylase whole cell enzyme assay
#1572DRG11-responsive (DRAGON) gene and uses thereof
#1573Compositions and methods for detecting pathogen infection
#1574Novel g protein-coupled receptor protein and dna thereof
#1575Labeled substrate conjugates for identifying enzyme inhibitors
#1576Method, composition and kit for antigenic binding of norwalk-like viruses
#1577Methods and compositions for cancer treatment relating to BRCA1 BRCT domain recognition of phosphorylated BACH1
#1578Identification of inhibitors of mitosis
#1579Screening methods for the identification of inhibitors of human immunodeficiency virus (HIV) viral protein R (Vpr) binding to the adenine nucleotide translocator (ANT)
#1580Method for screening compounds inhibiting signal transduction through inflammatory cytokines
#1581Rhesus monkey NURR1 nuclear receptor
#1582Specific binding agents for KSHV vIL-6 that neutralize a biological activity
#1583Antagonizing interleukin-21 receptor activity
#1584Modified defensins and their use
#1585Method of identifying protein kinase modulators and uses therefore
#1586Method for detecting acetyltransferase and deacetylase activities and method for screening inhibitors or enhancers of these enzymes
#1587Screening methods for inhibitors of protein-protein binding interactions
#1588Methods and compositions for modulating HGF/Met
#1589Molecules inhibiting hepatitis c virus protein synthesis and method for screening same
#1590Cell death inhibitor
#1591Ghrelin receptor inverse agonists for regulation of feeding behaviors
#1592Methods and compositions for using MHC class II invariant chain polypeptide as a receptor for macrophage migration inhibitory factor
#1593Methods of identifying modulators of ligand binding to ChemerinR polypeptides
#1594Method to modulate the immune system with a novel guanine nucleotide exchange factor
#1595Methods of modifying feeding behavior, compounds useful in such methods, and DNA encoding a hypothalamic atypical neuropeptide Y/peptide YY receptor (Y5)
#1596Identification and characterization of racemases, definition of protein signatures, and a test for detecting D-amino acid and for screening molecules capable of inhibiting the activity of racemase, especially proline racemase
#1597Tyrosylprotein sulfotransferases and methods of use thereof
#1598Novel 38594, 57312, 53659, 57250, 63760, 49938, 32146, 57259, 67118, 67067, 62092, FBH58295FL, 57255, and 57255alt molecules and uses therefor
#1599Method for the identification of inhibitors of the binding of ARE-containing mRNA and a HuR protein
#1600Negative regulation of hypoxia inducible factor 1 by OS-9
#1601Monomeric and dimeric fluorescent protein variants and methods for making same
#1602Screening methods for the identification of agents that inhibit SIRT1 Tat deacetylase activity
#1603Methods, compositions and compound assays for inhibiting amyloid-beta protein production
#1604Assay for TSG101 as inhibitors of HIV production
#1605Methods, compositions and compound assays for inhibiting amyloid-beta protein production
#1606Methods, compositions and compound assays for inhibiting amyloid-beta protein production
#1607Methods and compositions for regulating protein-protein interactions
#1608Multivalent antibody materials and methods for VEGF/PDGF family of growth factors
#1609Hedgehog antibodies
#1610Methods and compositions for activating VEGF-D and VEGF-C
#1611Angiotensin-converting enzyme-2 as a receptor for the SARS coronavirus
#1612Antibodies to cyclin E2 protein
#1613Compositions and methods for regulating peptidyltransferase activity and uses thereof
#1614Compositions and kits for detecting pathogen infection
#1615Novel treatment
#1616Compositions and methods for the identification of protein interactions in vertebrate cells
#1617Methods of using ZC1 and ZC3 kinase substrate phosphorylation as biomarkers
#1618Cytokine-, stress-, and oncoprotein-activated human protein kinase kinases
#1619Novel ubiquitin ligases as therapeutic targets
#1620Method of detecting and preventing Alzheimer's disease, particularly at prodromal and early stages
#1621Methods for affecting various diseases utilizing LXR compounds
#1622Glyceraldehyde 3-phosphate dehydrogenase-S (GAPDHS), a glycolytic anzyme expressed only in male germ cells, is a target for male contraception
#1623Method for identifying compounds that inhibit the activity of Myc
#1624Detection of proteases and screening for protease inhibitors
#1625Methods of modulating immune responses by modulating tim-1, tim-2 and tim-4 function
#1626Arrays of biological membranes and methods and use thereof
#1627Novel ubiquitin ligases as therapeutic targets
#1628Methods of diagnosing cervical cancer
#1629Toll-like receptor 9 modulators
#1630Compounds for treating human papillomavirus
#1631Methods for preventing or reducing ischemia/reperfusion induced myocardial cell death
#1632Isolated human protease proteins, nucleic acid molecules encoding human protease proteins, and uses thereof
#1633Isolated monomers of a type II serine proteinase inhibitor
#1634Peptides derived from cadherin and methods of use thereof
#1635Fluorescent protein variants and methods for making same
#1636Methods of screening of PP1-interacting polypeptides or proteins, peptides inhibiting PP1c binding to Bcl-2 proteins, Bcl-xand Bcl-w, and uses thereof
#1637Transgenic mouse whose genome comprises an APP having a mutation at amino acid 664
#1638Gtp cyclohydrolase II as as target for fungicides
#1639Immunocapture-based measurements of mammalian pyruvate dehydrogenase complex
#1640Method for identifying a modulator of the binding of CCX CKR polypeptide to a chemokine
#1641Detection of evolutionary bottlenecking by dna sequencing as a method to discover genes of value
#1642Heparinase III HLGAG fragments and uses thereof
#1643Method of screening therapeutic agents for nerve degeneration associated diseases
#1644Map3ks as modifiers of the p53 pathway and methods of use
#1645Compositions and Methods for Evaluating and Designing Nuclear Receptor Ligands that Modulate Co-Regulator Affinity
#1646Compositions and methods for promoting nerve regeneration
#1647Cell-based assays employing voltage and calcium dyes
#1648Probes for imaging protein phosphorylation and dephosphorylation and method for detecting and determining protein phosphorylation and dephosphorylation using the same
#1649Methods and products based on oligomerization of stress proteins
#1650Inhibitors of HIV membrane fusion
#1651Methods of identifying agents that mediate polypeptide aggregation
#1652Methods of evaluating phosphatase inhibitors
#1653Novel ubiquitin ligases as therapeutic targets
#1654Isolated human Ras-like proteins, nucleic acid molecules encoding these human Ras-like proteins, and uses thereof
#1655Nucleic acids encoding dendritic cell transmembrane serine protease
#1656Methods for treating cancer using Porimin as a target
#165724p3 receptors and uses thereof
#1658Anti-fusion assay
#1659Common ligand universal enzyme assay and compositions for use therein
#1660Novel ubiquitin ligases as therapeutic targets
#1661Compositions, methods and kits relating to anti-platelet autoantibodies and inhibitors thereof
#1662Toll-like receptor assays
#1663Recombinant baculovirus and virus-like particle
#1664Metadherin polypeptides, encoding nucleic acids and methods of use
#1665Novel spliced 5-HT1A receptors and methods, kits, and uses relating thereto
#1666Yeast cells expressing modified G proteins and methods of use therefor
#1667Modulating Robo: ligand interactions
#1668Monomeric and dimeric fluorescent protein variants and methods for making same
#1669Method of screening cocaine antagonists
#1670Pharmaceuticals and methods for treating hypoxia and screening methods therefor
#1671Method for screening a substance which can suppress degradation of a nuclear receptor or a substance which can promote degradation of a nuclear receptor
#1672Method for screening transcriptional coregulatory proteins of transcription factors, and androgen receptor transcriptional coregulatory proteins as targets for androgen receptor-dependent diseases
#1673Pappss as modifiers of the axin pathway and methods of use
#1674Monoclonal antibodies that bind Chemerin polypeptide
#1675Method for screening compounds which change the binding properties of a protein with a ligand
#1676Use of serum amyloid a gene in diagnosis and treatment of glaucoma and identification of anti-glaucoma agents
#1677Immunocapture of mitochondrial protein complexes
#1678Compositions and method for regulation of calcium-dependent signaling in brain
#1679Targeted polypeptide degradation
#1680Imaging regulated protein-protein interactions in cells and living animals by enhanced luciferase protein fragment complementation
#1681Identification of active-site inhibitors of glycosyltransferases using a generalizable high-throughput screen
#1682Inhibitors of amyloid precursor protein processing
#1683Compositions for manipulating the lifespan and stress response of cells and organisms
#1684Methods and compositions for identifying therapeutic compounds with GS-9005 ester hydrolase B
#1685Methods and compositions for identifying therapeutic compounds with GS-7340 ester hydrolase
#1686Methods and compositions for identifying therapeutic compounds with GS-9005 ester hydrolase A
#1687Methods for identifying modulators of intracellular aggregate formation
#1688Homogeneous fluorescence polarization assay for high throughput screening
#1689Novel cell cycle genes required for mitotic entry
#1690Cell surface tropomyosin as a target of angiogenesis inhibition
#1691Novel proteins and dnas thereof
#1692Assay and treatment
#1693Method, composition, and kit to design, evaluate, and/or test compounds that modulate regulatory factor binding to nucleic acids
#1694Human papillomavirus inhibitors
#1695Manganese ion regulation of reverse transcriptase activity and methods of modulating same
#1696Methods for diagnosis and treatment of epithelial-derived cancers
#1697Imaging the activity of extracellular protease in cells using mutant anthrax toxin protective antigens that are cleaved by specific extracellular proteases
#1698Methods for diagnosis and treatment of epithelial-derived cancers
#1699Drug for regenerating tissue and vessel and method therefor
#1700Compositions, methods and assays related to secretase cleavage specificity
#1701Methods for selective targeting
#1702Compositions and methods for treating inflammatory disorders
#1703Molecules and methods for inhibiting shedding of KIM-1
#1704Method and composition for treating immune complex associated disorders
#1705Hairless protein-interacting partner complexes and methods thereof for the beautification and/or improvement of mammalian skin
#1706Methods for the identification of inhibitors of biotin synthase expression or activity in plants
#1707Cell-free methods for identifying compounds that affect toll-like receptor 9 (TLR9) signaling
#1708Fluorescent probes for use in protein kinase inhibitor binding assay
#1709Complexes and methods of using same
#1710Substrates and assays for beta-secretase
#1711Compositions for manipulating the lifespan and stress response of cells and organisms
#1712Process for screening fungitoxic compounds
#1713Solution-based methods for detecting MHC-binding peptides
#1714Modified tachykinin receptors
#1715Use of inhibitors of glycogen synthase-3 to augment CD28 dependent -T-cell responses
#1716JAB1 as a prognostic marker and a therapeutic target for human cancer
#1717Mutant IGFBP-3 molecules that do not bind to IGFS, but retain their ability to functionally bind IGFBP-3 receptor
#1718Multiplex binding and activity assays
#1719Recruitment of mst1 or mst2 protein kinase to induce apoptosis in eukaryotic cells
#1720Complexes of GPCR142 and relaxin3 or INSL5, and their production and use
#1721Calmodulin independent activation of nitric oxide synthase
#1722Methods of modulating cell death based on the Bit1/AES regulatory pathway
#1723Probe for visualizing phosphorylation/dephosphorylation of protein and method of detecting and quantifying phosphorylation/dephosphorylation of protein
#1724Substituted aryl 1, 4-pyrazine derivatives
#1725Phosphoprotein target for insulin and its antagonists
#1726Methods for the identification of inhibitors of porphobilinogen deaminase as antibiotics
#1727Pain signaling molecules
#1728Agent for controlling circadian rhythm disorder
#1729Novel biomarkers of aggrecanase activity
#1730Methods and compositions for modulating HGF/Met
#1731Methods of modulating drug clearance mechanisms by altering SXR activity
#1732Method for alleviating pain using sphingosine-1-phosphate and related compounds, and assays for identifying such compounds
#1733Fluorescence polarization method for determining viral inhibitors
#1734Methods and compounds useful to induce apoptosis in cancer cells
#1735Protein interaction mapping
#1736Allosteric probes and methods
#1737HIV-1 VPR interactions with mitochondrial apoptosis inducing factor and methods of using the same
#1738Novel method for screening inhibitors of the linkage between the neuronal nitric oxide synthase associated protein and the protein inhibiting neuronal nitric oxide synthase
#1739Use of VLCFAE for identifying herbicidally active compounds
#1740Germinal center kinase proteins, compositions, and methods of use
#1741Screening for hepatitis c virus entry inhibitors
#1742Use of small molecule radioligands to discover inhibitors of amyloid-beta peptide production and for diagnostic imaging
#1743Inhibition of viral replication by targeting RNA-DNA complexes
#1744Method of identifying compounds that specifically inhibit the anaphase promoting complex
#1745Cytokine receptor
#1746Use of insulin response modulators in the treatment of diabetes and insulin resistance
#1747IL-1 zeta, IL-1 zeta splice variants and Xrec2 DNAs and polypeptides
#1748IL-1 zeta, IL-1 zeta splice variants and Xrec2 DNAs and polypeptides
#1749TSG101 as inhibitor of HIV production
#1750In vitro assays for inhibitors of hiv capsid conformational changes and for hiv capsid formation
#1751Use of VLCFAE for identifying herbicidally active compounds
#1752IL-1 zeta, IL-1 zeta splice variants and Xrec2 DNAS and polypeptides
#1753Assays and kits for detecting protein binding
#1754Polynucleotide encoding IL-1 zeta, TDZ.1 isoform polypeptide
#1755Ptp10d, tec protein tyrosine kinase and edtp homologous proteins involved in the regulation of energy homeostasis
#1756Methods and compositions for treating hcap associated diseases
#1757SHC proteins as therapeutic targets in proliferative diseases
#1758Inhibitor of demethylase, antitumorigenic agent, and an in vitro assay for demethylase inhibitors
#1759Diagnosis and treatment of AUR1 and/or AUR2 related disorders
#1760COVID-19 spike-ACE2 binding assay for drug and antibody screening
#1761Covid-19 spike-ACE2 binding assay for drug and antibody screening
#1762Methods of screening for sortilin binding antagonists
#1763Inhibitors of the FKBP51 protein from a high-throughput drug screen and methods of use