METHOD FOR IDENTIFYING ANTIBIOTIC TARGETS

DETERMINING A PROBABILISTIC DIAGNOSIS OF CANCER BY ANALYSIS OF GENOMIC COPY NUMBER VARIATIONS

RNA-STITCH SEQUENCING: AN ASSAY FOR DIRECT MAPPING OF RNA : RNA INTERACTIONS IN CELLS

Cross-network genomic data user interface

Secure genomic data accessioning

K-mer database for organism identification

GENOMIC NETWORK SERVICE USER INTERFACE

SYSTEM AND METHOD FOR POLYGENIC PHENOTYPIC TRAIT PREDISPOSITION ASSESSMENT USING A COMBINATION OF DYNAMIC NETWORK ANALYSIS AND MACHINE LEARNING

POLYGENIC RECOMMENDATIONS BASED ON INDIVIDUALIZED EXPRESSION OF GENETIC VARIANTS

Hybridized storage optimization for genomic workloads

Determining potential cancer therapeutic targets by joint modeling of survival events

METHOD, SYSTEM AND NON-TRANSITORY COMPUTER-READABLE RECORDING MEDIUM FOR PROVIDING PREDICTION ABOUT BREEDING

DETERMINING A PROBABILISTIC DIAGNOSIS OF CANCER BY ANALYSIS OF GENOMIC COPY NUMBER VARIATIONS

Biomarker for diagnosing overactive bladder disease and screening method of therapeutic agents using the same

Systems, devices, and/or processes for OMIC and/or behavioral content processing

Single sample genetic classification via tensor motifs

Bio-information data providing method, bio-information data storing method and bio-information data transferring system based on multiple blockchains

Soybean variety

Method capable of differentiating fetal sex and fetal sex chromosome abnormality on various platforms

Systems and methods for leveraging relatedness in genomic data analysis

BIOMETRIC HOT TUB TEMPERATURE CONTROL

Determination of MAPK-AP-1 pathway activity using unique combination of target genes

PATIENT DIAGNOSIS AND TREATMENT BASED ON GENOMIC TENSOR MOTIFS

SYSTEMS AND METHODS FOR IDENTIFYING RESPONDERS AND NON-RESPONDERS TO IMMUNE CHECKPOINT BLOCKADE THERAPY

Methods and systems for identifying hybrids for use in plant breeding

Differential gene set enrichment analysis in genome-wide mutational data

Neural network based selection of representative patients

Determining a nucleic acid sequence imbalance using multiple markers

Optimization of multigene analysis of tumor samples

TFPI inhibitors and methods of use

BIOLOGICAL SEQUENCE FINGERPRINTS

METHODS OF DETERMINING TISSUES AND/OR CELL TYPES GIVING RISE TO CELL-FREE DNA, AND METHODS OF IDENTIFYING A DISEASE OR DISORDER USING SAME

High resolution allele identification

DAISY CHAIN FOR PHASING POLYPLOID

TRIE-BASED POLYPLOID PHASING

Systems and Methods For RNA Analysis In Functional Confirmation Of Cancer Mutations

Methods for using nucleic acids to store, retrieve and access information comprising a text, image, video or audio format

PHENOTYPIC PERSONALIZED MEDICINE: ADAPTIVE OPTIMIZATION OF PATIENT-SPECIFIC COMBINATION THERAPY

Method for determining the risk of developing acute kidney injury in a human subject with acute myocardial infarction and inhibiting such development

Optimization of multigene analysis of tumor samples

Image-based circular plot recognition and interpretation

Deep learning-based splice site classification

METAGENOMIC NGS READ CLASSIFICATION AND INTRINSIC ACCURACY MEASURE THROUGH SEQUENCE FRAGMENTATION

Deep learning-based aberrant splicing detection

DRUG REPURPOSING BASED ON DEEP EMBEDDINGS OF GENE EXPRESSION PROFILES

Target-associated molecules for characterization associated with biological targets

ERROR CORRECTION IN ANCESTRY CLASSIFICATION

METHOD AND KIT FOR GENETIC ANALYSIS

METHOD FOR MAPPING SPINAL MUSCULAR ATROPHY (“SMA”) LOCUS AND OTHER COMPLEX GENOMIC REGIONS USING MOLECULAR COMBING

METHODS FOR PREDICTING OR DETECTING DISEASE

METHOD OF SEQUENCE TYPING WITH IN SILICO APTAMERS FROM A NEXT GENERATION SEQUENCING PLATFORM

Method of detecting fetal chromosomal aneuploidy

GENETIC VARIANT IDENTIFICATION FOR COMPLEX DISEASE

GENETIC VARIANT IDENTIFICATION FOR COMPLEX DISEASE

METHOD OF ANALYZING MICROBIOME

METHODS AND TOOLS FOR DETECTING, DIAGNOSING, PREDICTING, PROGNOSTICATING, OR TREATING A NEUROBEHAVIORAL PHENOTYPE IN A SUBJECT

Determination of JAK-STAT3 pathway activity using unique combination of target genes

Identification and use of glycopeptides as biomarkers for diagnosis and treatment monitoring

Systems and methods for discovery and analysis of markers

BLOCKCHAIN BASED PROACTIVE CHROMOSOMAL DETERMINATION

Universal method to determine real-time PCR cycle threshold values

Gene Expression Profile Algorithm for Calculating a Recurrence Score for a Patient with Kidney Cancer

Methods of using miRNAs from bodily fluids for detection and differentiation of neurodegenerative diseases

Methods, devices, and computer program products for standardizing a fermentation process

Methods to compress, encrypt and retrieve genomic alignment data

SYSTEM AND METHOD FOR ANALYZING GENOTYPE USING GENETIC VARIATION INFORMATION ON INDIVIDUAL'S GENOME

Method and System for DNA Analysis

METHOD AND SYSTEM FOR MICROBIOME-DERIVED DIAGNOSTICS AND THERAPEUTICS FOR CONDITIONS ASSOCIATED WITH THYROID HEALTH ISSUES

Tracking infections in hospital environments

SYSTEMS, METHODS, AND PROCESSOR-READABLE MEDIA FOR DETECTING DISEASE CAUSAL VARIANTS

Systems and methods for characterization of viability and infection risk of microbes in the environment

Methods for epitope mapping

Methods of treating cancer

METHOD AND SYSTEM FOR MICROBIOME-DERIVED DIAGNOSTICS AND THERAPEUTICS FOR CONDITIONS ASSOCIATED WITH GASTROINTESTINAL HEALTH

Universal short adapters with variable length non-random unique molecular identifiers

GENETIC TESTING FOR PREDICTING RESISTANCE OF SALMONELLA SPECIES AGAINST ANTIMICROBIAL AGENTS

Methods And Systems For Profiling Personalized Biomarker Expression Perturbations

MICROORGANISM-RELATED SIGNIFICANCE INDEX METRICS

Monitoring and diagnosis for immunotherapy, and design for therapeutic agent

Computational phylogenetic analysis

Method and system for characterization for female reproductive system-related conditions associated with microorganisms

SEQUENCING ANALYSIS OF CIRCULATING DNA TO DETECT AND MONITOR AUTOIMMUNE DISEASES

Compositions and methods for discovery of causative mutations in genetic disorders

SUB-POPULATION DETECTION AND QUANTIZATION OF RECEPTOR-LIGAND STATES FOR CHARACTERIZING INTER-CELLULAR COMMUNICATION AND INTRATUMORAL HETEROGENEITY

EPITOPE MIMICS

Secure computing systems and methods

Systems and methods for determining the integrity of test strings with respect to a ground truth string

MACHINE LEARNING BASED ANTIBODY DESIGN

Using cell-free DNA fragment size to determine copy number variations

DATA COLLECTION METHOD TO BE USED FOR CLASSIFYING CANCER LIFE

SYSTEMS AND METHODS FOR STRING REPRIORITIZATION

PREDICTING DISEASE BURDEN FROM GENOME VARIANTS

GENETIC TEST FOR LIVER COPPER ACCUMULATION IN DOGS

METHODS AND COMPOSITIONS FOR THE DETECTION, CLASSIFICATION, AND DIAGNOSIS OF SCHIZOPHRENIA

Compression/decompression method and apparatus for genomic variant call data

MACHINE BASED CLASSIFIER FOR GENETIC INTERACTIONS

BIOMARKER-DRIVEN MOLECULARLY TARGETED COMBINATION THERAPIES BASED ON KNOWLEDGE REPRESENTATION PATHWAY ANALYSIS

MULTI-MODAL PROSTATE CANCER MARKER

Noninvasive detection of fetal aneuploidy in egg donor pregnancies

DNA SEQUENCE PROCESSING METHOD AND DEVICE

Systems and Methods for Analyzing Nucleic Acids

Methylation pattern analysis of tissues in a DNA mixture

Materials and methods for determining metabolizer status in humans

ENHANCED APPLICATIONS OF MOLECULAR LIBRARIES BASED ON STRUCTURE/FUNCTION ANALYSIS

Method for determining kinetic profiles in drug discovery

SYSTEMS AND METHODS FOR DETERMINING IMPACT OF AGE RELATED CHANGES IN SPERM EPIGENOME ON OFFSPRING PHENOTYPE

COMPUTER-IMPLEMENTED METHODS FOR AUTOMATED ANALYSIS AND PRIORITIZATION OF VARIANTS IN DATASETS

NONINVASIVE PRENATAL GENOTYPING OF FETAL SEX CHROMOSOMES

Device and method of using rodent vocalizations for automatic classification of animal behavior

Automatically identifying statistically significant combination therapies from clinical data

METHOD AND DEVICE FOR CALCULATING BINDING FREE ENERGY, AND PROGRAM

Resource allocation method and apparatus for gene analysis

Gene fusions and gene variants associated with cancer

Method for genotyping clonotype profiles using sequence tags

COMPUTER-BASED SYSTEMS AND METHODS FOR MONITORING THE HEART MUSCLE OF A PATIENT WITH COMPREHENSIVE CONTEXTUAL OVERSIGHT

Method and system for identification and classification of operational taxonomic units in a metagenomic sample

High-throughput identification of patient-specific neoepitopes as therapeutic targets for cancer immunotherapies

Attribute identification based on seeded learning

METHODS, SYSTEMS, AND APPARATUS FOR IDENTIFYING TARGET SEQUENCES FOR CAS ENZYMES OR CRISPR-CAS SYSTEMS FOR TARGET SEQUENCES AND CONVEYING RESULTS THEREOF

GENETIC TESTING AND SUITABILITY SIMULATING SYSTEM

CURATED GENETIC DATABASE FOR IN SILICO TESTING, LICENSING AND PAYMENT

Information processing apparatus, suspect information generation method and program

Quantum mechanical/X-ray crystallography diagnostic for proteins

GENOMIC SERVICES PLATFORM SUPPORTING MULTIPLE APPLICATION PROVIDERS

APPARATUS, SYSTEM AND METHOD FOR ANALYZING DISEASE SAMPLE

Measurement and comparison of immune diversity by high-throughput sequencing

Immuno-oncology applications using next generation sequencing

Methods for proteome docking to identify protein-ligand interactions

SYSTEM AND METHOD FOR PROCESSING GENOTYPE INFORMATION RELATING TO MEDICALLY-ASSISTED TREATMENT REGARDING WITHDRAWAL OR PAIN

Methods and systems for de novo peptide sequencing using deep learning

Systems and methods for storing, processing and utilizing proprietary genetic information

REPEAT PROTEIN ARCHITECTURES

Feature selection for efficient epistasis modeling for phenotype prediction

Feature selection for efficient epistasis modeling for phenotype prediction

Methods and materials for determining pain sensitivity and predicting and treating related disorders

Healthcare analysis stream management

Cancer evolution detection and diagnostic

Reliable and Secure Detection Techniques for Processing Genome Data in Next Generation Sequencing (NGS)

METHOD FOR PREDICTING EFFICACY OF DRUGS IN A PATIENT

METHODS OF ESTIMATING GAMETE VARIATION

Methods and processes for non-invasive detection of a microduplication or a microdeletion with reduced sequence read count error

Methods of screening

IDENTIFYING ANTIGEN CLUSTERS FOR MONITORING A GLOBAL STATE OF AN IMMUNE SYSTEM

Systems For Biomarker Detection

HAPLOTYPING OF HLA LOCI WITH ULTRA-DEEP SHOTGUN SEQUENCING

DETECTION OF CHROMOSOME ABNORMALITIES

SYSTEMS AND METHODS FOR ENCODING GENOMIC GRAPH INFORMATION

Method and System for the Use of Biomarkers for Regulatory Dysfunction in Disease

Secure secret-sharing-based crowdsourcing for large-scale association studies of genomic and phenotypic data

Natural product and genetic data analysis and discovery system, method and computational platform therefor

Devices, compositions and methods for imaging with Raman scattering

Non-invasive diagnosis of graft rejection in organ transplant patients

Non-invasive diagnosis of graft rejection in organ transplant patients

Systems and Methods for the Interpretation of Genetic and Genomic Variants via an Integrated Computational and Experimental Deep Mutational Learning Framework

GENETIC TESTING FOR PREDICTING RESISTANCE OF ENTEROBACTER SPECIES AGAINST ANTIMICROBIAL AGENTS

Methods of protein evolution

System, device and a method for providing a therapy or a cure for cancer and other pathological states

METHOD FOR DETERMINING COPY-NUMBER VARIATION IN SAMPLE COMPRISING MIXTURE OF NUCLEIC ACIDS

PROTEIN DESIGN METHOD AND SYSTEM

Method for administering a checkpoint blockade therapy to a subject

SYSTEMS AND METHODS FOR IDENTIFYING RESPONDERS AND NON-RESPONDERS TO IMMUNE CHECKPOINT BLOCKADE THERAPY

Selective peptide antagonists

Genetic resistance prediction against antimicrobial drugs in microorganism using structural changes in the genome

Cancer antigen targets and uses thereof

Risk calculation for evaluation of fetal aneuploidy

Rapid evaporative ionisation mass spectrometry (“REIMS”) and desorption electrospray ionisation mass spectrometry (“DESI-MS”) analysis of swabs and biopsy samples

Individual and cohort pharmacological phenotype prediction platform

Methods of Processing and Classifying Microarray Data for the Detection and Characterization of Pathogens

Primer design using indexed genomic information

Secure communication of sensitive genomic information using probabilistic data structures

Genome and self-evolution of AI

Systems and methods for the analysis of proximity binding assay data

METHODS FOR DETECTING COPY-NUMBER VARIATIONS IN NEXT-GENERATION SEQUENCING

Systems and methods for recognizing, classifying, recalling and analyzing information utilizing SSM sequence models

System and methods for deriving gene signature biomarkers of response to PD-1 antagonists

METHODS AND PROCESSES FOR NON-INVASIVE ASSESSMENT OF GENETIC VARIATIONS

METHOD OF DETECTING CHROMOSOME ABNORMALITY IN EMBRYO BY USING BLASTOCYST CULTURE

SYSTEM AND METHOD FOR PROCESSING GENOTYPE INFORMATION RELATING TO NSAID RISK

METHOD, SYSTEM AND COMPUTER READABLE MEDIUM FOR DETERMINING BASE INFORMATION IN PREDETERMINED AREA OF FETUS GENOME

USE OF CLINICAL KNOWLEDGE TO IMPROVE USE OF NEXT GENERATION SEQUENCING

INTERACTIVE PRECISION MEDICINE EXPLORER FOR GENOMIC ABBERATIONS AND TREATMENT OPTIONS

Mantle phenotype detection in palm

Compression and annotation of digital waveforms from serial read next generation sequencing to support remote computing base calling

System, Method and Apparatus for Determining the Effect of Genetic Variants

Using cell-free DNA fragment size to detect tumor-associated variant

Protein biomarkers for memory loss

Biomarkers and methods of diagnosing and prognosing mild traumatic brain injuries

Monitoring Dysregulated Serum Complement, Coagulation, and Acute-Phase Inflammation Sub-Proteomes Associated with Cancer

METHODS FOR PREDICTING PALM OIL YIELD OF A TEST OIL PALM PLANT

Multiallelic Genotyping of Single Nucleotide Polymorphisms and Indels

Predicting health outcomes

Advanced Tensor Decompositions For Computational Assessment And Prediction From Data

CHAIN OF CUSTODY FOR BIOLOGICAL SAMPLES AND BIOLOGICAL MATERIAL USED IN GENOTYPING TESTS

SYSTEM AND METHOD FOR CLEANING NOISY GENETIC DATA AND DETERMINING CHROMOSOME COPY NUMBER

System and method for automatically discovering, characterizing, classifying and semi-automatically labeling animal behavior and quantitative phenotyping of behaviors in animals

Rigorous method and apparatuses for the analysis of complex mixtures of organic molecules with an enhanced degree of information extraction

Image acquisition methods for simultaneously detecting genetic rearrangement and nuclear morphology

Techniques for determining whether an individual is included in ensemble genomic data

Methods of Cross Correlation of Biofield Scans to Enome Database, Genome Database, Blood Test, and Phenotype Data

Systems and methods for use in identifying multiple genome edits and predicting the aggregate effects of the identified genome edits

Identifying a de novo fetal mutation from a maternal biological sample

Chromosome Representation Determinations

Typing and Assembling Discontinuous Genomic Elements

Methods of associating genetic variants with a clinical outcome in patients suffering from age-related macular degeneration treated with anti-VEGF

Systems and methods for detecting structural variants

Gene test platform method

CONVOLUTIONAL ARTIFICIAL NEURAL NETWORKS, SYSTEMS AND METHODS OF USE

Lung cancer biomarkers and uses thereof

DETERMINATION OF TGF-BETA PATHWAY ACTIVITY USING UNIQUE COMBINATION OF TARGET GENES

SYSTEMS AND METHODS TO DETECT COPY NUMBER VARIATION

PHASING ANALYSIS WITH DYNAMIC PROGRAMMING ALGORITHM

LINKAGE DISEQUILIBRIUM METHOD AND DATABASE

Analyzing metagenomics data

Systems and Methods for Developing Diagnostic Tests Based on Biomarker Information from Legacy Clinical Sample Sets

Personalized Health-Information Based on Genetic Data

Thermodynamic measures on protein-protein interaction networks for cancer therapy

Predicting skin age based on the analysis of skin flora and lifestyle data

Method and system for screening of cells and organoids

Method for designing RNA binding protein utilizing PPR motif, and use thereof

SYSTEM AND METHOD FOR PROCESSING GENOTYPE INFORMATION RELATING TO NON-OPIOID RESPONSE

A METHOD FOR CD4+ T-CELL EPITOPE PREDICTION USING ANTIGEN STRUCTURE

INTEGRATED METHOD AND SYSTEM FOR IDENTIFYING FUNCTIONAL PATIENT-SPECIFIC SOMATIC ABERATIONS USING MULTI-OMIC CANCER PROFILES

Bioinformatics systems, apparatuses, and methods executed on a quantum processing platform

Metabolite, annotation, and gene integration system and method

METHODS AND SYSTEMS FOR SOCIAL NETWORKING BASED ON NUCLEIC ACID SEQUENCES

Information processing device, method, and computer-readable recording medium

Methods and systems for tumor detection

Size-based genomic analysis

METHOD AND KIT FOR CHARACTERIZING MICROORGANISMS

Method of using genetic architecture of phenomic-enabled canopy coverage in

System and methods for identifying a base call included in a target sequence

METHOD FOR INTERROGATING MIXTURES OF NUCLEIC ACIDS

Sensitivity and the dynamic range of photometric assays by generating multiple calibration

Apparatus, Compositions, and Methods for Assessment of Chronic Obstructive Pulmonary Disease Progression Among Rapid and Slow Decline Conditions

METHOD FOR SELECTING A TRANSPLANTATION DONOR OR DONOR MATERIAL USING LOW OR INTERMEDIATE HLA TYPING INFORMATION

GENETIC TESTING FOR PREDICTING RESISTANCE OF MORGANELLA SPECIES AGAINST ANTIMICROBIAL AGENTS

Epitope focusing by variable effective antigen surface concentration

METHODS FOR ASSESSING RISK OF FEMALE INFERTILITY

Systems and methods for prioritizing variants of unknown significance

DISEASE RISK PREDICTION METHOD, AND DEVICE FOR PERFORMING SAME

Method for managing complex genomic data workflows

Analysis of genetic variants

MOLECULAR BASED DECISION SUPPORT SYSTEM FOR CANCER TREATMENT

Methods for assessing response to inflammatory disease therapy withdrawal

Computer implemented identification of genetic similarity

Method for evaluating physical conditions, method for presenting information, and method for screening for substance capable of improving or preventing physical conditions

Pathogen detection using next generation sequencing

DEVICE, SYSTEM AND METHOD FOR MANAGING TREATMENT OF AN INFLAMMATORY AUTOIMMUNE DISEASE OF A PERSON

IDENTIFICATION OF FACTORS FOR THE TREATMENT OF MITOCHONDRIAL AND AGE-RELATED DISEASES

Methods for non-invasive prenatal ploidy calling

Kit, apparatus, and method for detecting chromosome aneuploidy

Compensation for spectral crosstalk in mulitplex nucleic acid amplification

CANCER PROGNOSIS AND THERAPY BASED ON SYNTHEIC LETHALITY

BIOINFORMATICS SYSTEMS, APPARATUSES, AND METHODS FOR PERFORMING SECONDARY AND/OR TERTIARY PROCESSING

Droplet tagging contiguity preserved tagmented DNA

AUTOMATED GENETIC TEST COUNSELING

Systems And Methods For Patient-Specific Prediction Of Drug Responses From Cell Line Genomics

Bioinformatics systems, apparatuses, and methods for generating a De Bruijn graph

Methods and systems for predicting alloreactivity in transplantation

Cardiovascular risk event prediction and uses thereof

Genetic comparisons between grandparents and grandchildren

The Use of Bioinformatic Data in Autologous Cell Therapies

METHOD, AN ARRANGEMENT AND A COMPUTER PROGRAM PRODUCT FOR ANALYSING A BIOLOGICAL OR MEDICAL SAMPLE

Technique for identifying features

METHOD FOR PERFORMING GENOTYPING ANALYSIS

System and method for improved estimation of functional potential of genomes and metagenomes

Predicting suicidality using a combined genomic and clinical risk assessment

Methods for quantitative genetic analysis of cell free DNA

Multispecific antigen-binding proteins

Generation and use of simulated genomic data

ESTABLISHING A MACHINE LEARNING MODEL FOR CANCER ANTICIPATION AND A METHOD OF DETECTING CANCER BY USING MULTIPLE TUMOR MARKERS IN THE MACHINE LEARNING MODEL FOR CANCER ANTICIPATION

Systems and Methods for Detection of Aneuploidy

Enhanced amplicon sequencing analysis

SYSTEM AND METHOD FOR CLEANING NOISY GENETIC DATA AND DETERMINING CHROMOSOME COPY NUMBER

Method and system for estimating whether a female is pregnant based on a blood sample

Methods and compositions for cannabis characterization

Method and system for estimating a gender of a foetus of a pregnant female

GENERALIZED COMPUTATIONAL FRAMEWORK AND SYSTEM FOR INTEGRATIVE PREDICTION OF BIOMARKERS

Neural network architectures for linking biological sequence variants based on molecular phenotype, and systems and methods therefor

Methods for detecting mutation load from a tumor sample

Metabolic pathway and metabolite identification

Methods for the detection of genomic copy changes in DNA samples

Size-based analysis of fetal DNA fraction in plasma

SYSTEMS AND METHODS FOR ALIGNING SEQUENCES TO PERSONALIZED REFERENCES

Systems and methods for genotyping by angle configuration search

CODING GENOME RECONSTRUCTION FROM TRANSCRIPT SEQUENCES

System and method for cleaning noisy genetic data and determining chromosome copy number

System and method for cleaning noisy genetic data and determining chromosome copy number

Structure-based peptide inhibitors of P53 aggregation as a new approach to cancer therapeutics

DEVICE AND METHOD FOR DIAGNOSING CARDIOVASCULAR DISEASE USING GENOME INFORMATION AND HEALTH MEDICAL CHECKUP DATA

METHOD FOR OPTIMAL DESIGN OF POLYNUCLEOTIDES SEQUENCES FOR ANALYSIS OF SPECIFIC EVENTS IN ANY GENETIC REGION OF INTEREST

Compressed sensing for simultaneous measurement of multiple different biological molecule types in a sample

Methods and compositions for determining ploidy

Cancer neoepitopes

Nucleic acid-based data storage

SYSTEM, METHOD AND DEVICE FOR IDENTIFYING DISCRIMINANT BIOLOGICAL FACTORS AND FOR CLASSIFYING PROTEOMIC PROFILES

SYSTEM AND METHOD FOR PROCESSING GENOTYPE INFORMATION RELATING TO OPIOID RISK

Genetic marker for determining meat quality traits of pigs and use thereof

Predictive test for aggressiveness or indolence of prostate cancer from mass spectrometry of blood-based sample

PROTEOGENOMIC ANALYSIS SYSTEM AND METHODS