DOWN-REGULATION OF A HOMEODOMAIN-LEUCINE ZIPPER I-CLASS HOMEOBOX GENE FOR IMPROVED PLANT PERFORMANCE

Methods of treating cancer harboring hemizygous loss of TP53

Regulation of translation of expressed genes

Compositions and methods for modulating TTR expression

Antisense nucleic acids

Zn-DPA complex compounds and siRNA delivery systems containing the same

METHODS FOR MODULATING MECP2 EXPRESSION

Pericyte Long Non-Coding RNAs

DOUBLE-STRANDED OLIGONUCLEOTIDE MOLECULES TO P53 AND METHODS OF USE THEREOF

Car-expressing cells against multiple tumor antigens and uses thereof

Amphipathic peptide

Lipids and compositions for the delivery of therapeutics

RECOMBINANT GLUT1 ADENO-ASSOCIATED VIRAL VECTOR CONSTRUCTS AND RELATED METHODS FOR RESTORING GLUT1 EXPRESSION

Cochleates and methods of using the same to enhance tissue penetration of pharmacologically active agent

Beta-catenin inhibitors in cancer immunotherapy

SIGNATURE OF HEALTH

Glycaspis Brimblecombei Control Agents

COMPOSITIONS AND METHODS FOR EFFICACIOUS AND SAFE DELIVERY OF SIRNA USING SPECIFIC CHITOSAN-BASED NANOCOMPLEXES

Low molecular weight cyclic amine containing cationic lipids for oligonucleotide delivery

Treatment of NANOG related diseases by inhibition of natural antisense transcript to NANOG

Oligonucleotide compositions and uses thereof

ANTISENSE POLYNUCLEOTIDES TO INDUCE EXON SKIPPING AND METHODS OF TREATING DYSTROPHIES

Short interfering RNA for treating cancer

GENE EXPRESSION REGULATION SYSTEM OF SYNECHOCOCCUS ELONGATUS PCC 7942 AND APPLICATION THEREOF

Compositions and methods for inhibiting expression of the ALAS1 gene

Methods and compositions for treating and/or preventing a disease or disorder associated with abnormal level and/or activity of the IFP35 family of proteins

Method for diagnosing a molecular phenotype of a patient suffering from an illness accompanied by chronic inflammation

COMPOSITIONS AND METHODS FOR INSECTICIDAL CONTROL OF STINKBUGS

RNA interference mediated inhibition of catenin (cadherin-associated protein), beta 1 (CTNNB1) gene expression using short interfering nucleic acid (siNA)

TARGETING OLIGONUCLEOTIDES AND USES THEREOF TO MODULATE GENE EXPRESSION

Antisense oligonucleotides (ODN) against SMAD7 and uses thereof in medical field

Pharmaceutical Composition Consisting Of RNA Having Alkali Metal As Counter Ion And Formulated With Dications

Compositions and methods using capsids resistant to hydrolases

Multimeric oligonucleotide compounds having non-nucleotide based cleavable linkers

NON-IONIC, LOW OSMOLAR CONTRAST AGENTS FOR DELIVERY OF ANTISENSE OLIGONUCLEOTIDES AND TREATMENT OF DISEASE

MicroRNA therapy for pancreatic cancer

siRNA compounds comprising terminal substitutions

Pharmaceutical composition for treating cancer comprising microrna as active ingredient

Oligonucleotide therapy for leber congenital amaurosis

MATERIALS AND METHODS FOR TREATMENT OF HEMOGLOBINOPATHIES

Acyl-amino-LNA and/or hydrocarbyl-amino-LNA oligonucleotides

Methods and compositions for wound healing

Extracellular vesicles for agent delivery

Hybrid oligonucleotides and uses thereof

Oligomers Having Bicyclic Scaffold Moeities

COATED CHITOSAN-BASED POLYPLEX FOR DELIVERY OF NUCLEIC ACIDS

Delivering functional nucleic acids to mammalian cells via bacterially-derived, intact minicells

Technology for the Preparation of Microparticles

MICRORNAS IN NEURODEGENERATIVE DISORDERS

Recombinant AAV variants and uses thereof

Compositions and methods for inhibiting gene expression of factor XII

Disulfide-containing alkyne linking agents

Double strand RNA as molecular biopesticides for RNA interference through feeding in the hemipteran invasive insect pest, brown marmorated stink bug

Variant RNAi

LNA OLIGONUCLEOTIDES WITH ALTERNATING FLANKS

Long Non-Coding RNA For The Treatment Of Endothelial Dysfunction

Circular RNA For The Diagnosis Of Cardiovascular And Inflammatory Diseases

Oligonucleotide sequences targeting transcription factor TSC22D4 for the treatment of insulin resistance

Compositions for modulating expression of C9ORF72 antisense transcript

DOUBLE STRAND RNA DELIVERY SYSTEM FOR PLANT-SAP-FEEDING INSECTS

Compositions and methods for enhancing homologous recombination

Facile assembly of soft nanoarchitectures and co-loading of hydrophilic and hydrophobic molecules via flash nanoprecipitation

Nanoparticle-protein complex for intracellular protein delivery

Biological Materials and Uses Thereof

Compositions and methods for regulating arterial tone

Endonuclease targeting blood coagulation factor VIII gene and composition for treating hemophilia comprising same

Lipid Nanoparticle Compositions and Methods of Making and Methods of Using the Same

Hyperbranched polymers and polyplexes and DNA or RNA delivery systems including the same

Materials and methods for treatment of hemoglobinopathies

Use of isocitrate dehydrogenase 1 as a diagnostic and prognostic biomarker and therapeutic target for lung cancers

Method for improving heterologous synthesis of into polyketides and use of same

Morpholino oligonucleotide manufacturing method

Methods for the treatment of Leber congenital amaurosis

Methods and agents to increase therapeutic dystrophin expression in muscle

Treatment of facioscapulohumeral dystrophy

Novel Therapeutic Agent for Septicemia, and a Method for Screening for Same

LNA Gapmer Oligonucleotides Comprising Chiral Phosphorothioate Linkages

EXON SKIPPING COMPOSITIONS FOR TREATING MUSCULAR DYSTROPHY

Oligonucleotide compositions and methods of making the same

Oligonucleotide compositions and methods of making the same

Compositions and methods for monitoring, diagnosis, prognosis, detection, and treatment of cancer

CRISPR-CAS system for a yeast host cell

Treatment of erythropoietin (EPO) related diseases by inhibition of natural antisense transcript to EPO

Double-stranded ribonucleic acid as control against insects

Compositions and methods to promote erythropoiesis

Oligomeric compounds and compositions for use in modulation of small non-coding RNAs

METHOD OF ENHANCING MIR-185 EXPRESSION TO REDUCE LOW DENSITY LIPOPROTEIN/CHOLESTEROL ACCUMULATION IN A CELL

ANTISENSE COMPOUNDS AND USES THEREOF

Double-stranded oligonucleotide molecules to DDIT4 and methods of use thereof

Synthetic promoters for high throughput screening and gene modulation

Compounds and methods for the modulation of proteins

Compositions and methods thereof for down-regulation of genes following oral delivery of an RNAi molecule bioencapsulated within plant cells

Recombinant DNA constructs and methods for controlling gene expression

Composition for reducing cellular senescence level including activity inhibitor inhibiting DCUN1D3 activity or expression inhibitor inhibiting expression of DCUN1D3-encoding gene and use thereof

Antisense oligonucleotides for inducing exon skipping and methods of use thereof

Treatment of sodium channel, voltage-gated, alpha subunit (SCNA) related diseases by inhibition of natural antisense transcript to SCNA

COMPOUNDS AND METHODS FOR IMPROVED CELLULAR UPTAKE OF ANTISENSE COMPOUNDS

Reducing intron retention

COMPOSITIONS AND METHODS

Sequence Specific and Organism Specific Antimicrobials and Related Materials and Methods

Compositions and methods for controlling

Plant regulatory elements and uses thereof

EXON SKIPPING COMPOSITIONS FOR TREATING MUSCULAR DYSTROPHY

Heterodimeric Cas9 and methods of use thereof

Inflammatory disease diagnosis and methods of treatment using down-regulators of lipopolysaccharide-responsive beige-like anchor

MICRONEEDLE ARRAYS FOR ACTIVE AGENT DELIVERY

Methods and devices for preparation of lipid nanoparticles

Blood biomarkers for respiratory infections

Analysis of nucleic acids associated with single cells using nucleic acid barcodes

MicroRNAs Sensitize Cancers to Therapy

FULLY STABILIZED ASYMMETRIC SIRNA

RNA targeting in alpha-synucleinopathies

Compositions comprising alternating 2′-modified nucleosides for use in gene modulation

Methods for treatment of alport syndrome

MICRORNA COMBINATIONS FOR ANTI-CANCER THERAPEUTICS

Reduction of off-target RNA interference toxicity

EXON SKIPPING COMPOSITIONS FOR TREATING MUSCULAR DYSTROPHY

EXON SKIPPING COMPOSITIONS FOR TREATING MUSCULAR DYSTROPHY

RAAV-BASED COMPOSITIONS AND METHODS FOR TREATING ALPHA-1 ANTI-TRYPSIN DEFICIENCIES

PARENTAL RNAI SUPPRESSION OF CHROMATIN REMODELING GENES TO CONTROL COLEOPTERAN PESTS

REVERSIR TM COMPOUNDS

COMPOSITIONS AND METHODS FOR EFFICIENT GENE EDITING IN E. COLI USING GUIDE RNA/CAS ENDONUCLEASE SYSTEMS IN COMBINATION WITH CIRCULAR POLYNUCLEOTIDE MODIFICATION TEMPLATES

Method for modifying T cell population

RECOMBINANT CELLS COMPRISING miRNA MIMICS

Compositions for enhancing transport of molecules into cells

Methods for treating spinal muscular atrophy

Simultaneous detection of cannibalism and senescence as prognostic marker for cancer

Treatment of angiogenesis disorders

Methods and means of generating IL-17 associated antitumor effector cells by inhibition of NR2F6 inhibition

PHARMACEUTICAL COMPOSITIONS COMPRISING MICRORNA

METHODS AND COMPOSITIONS FOR SELECTIVELY ELIMINATING CELLS OF INTEREST

METHODS AND COMPOSITIONS FOR REGULATING IRON HOMEOSTASIS BY MODULATION OF BMP-6

Methods for tuning carotenoid production levels and compositions in and genera

VLP WITH A FUSION PROTEIN

ANTI-ARRHYTHMICITY AGENTS

Luterion and separating and culturing methods for same

Formulations for targeted release of agents under low pH conditions and methods of use thereof

PROCESSES FOR PRODUCING STABLE EXOSOME FORMULATIONS

EXTRACELLULAR VESICLES WITH ENHANCED POTENCY

Treatment and prevention of thrombosis using an anti-miR

OLIGONUCLEOTIDE PROBES AND USES THEREOF

ACTIVITY-DEPENDENT GENE PAIRS AS THERAPEUTIC TARGETS AND METHODS AND DEVICES TO IDENTIFY THE SAME

Delivery across cell plasma membranes

Methods and compositions for transducing lymphocytes and regulating the activity thereof

Treatment of fibroblast growth factor 21 (FGF21) related diseases by inhibition of natural antisense transcript to FGF21

Angiopoietin-like 3 (ANGPTL3) iRNA compositions and methods of use thereof

Modulation of alternative MDM2 splicing

Factor V/Va-targeting aptamer compositions and methods of using the same

COMPOSITIONS AND METHODS TO CONTROL INSECT PESTS

TREATMENT OF SODIUM CHANNEL, VOLTAGE-GATED, ALPHA SUBUNIT (SCNA) RELATED DISEASES BY INHIBITION OF NATURAL ANTISENSE TRANSCRIPT TO SCNA

RNAI induced huntingtin gene suppression

Mitochondrial phosphate carrier targets for treating soft-tissue calcification

Inhibitors Of Lactate Transporters For Use In The Treatment Of Inflammatory Diseases

ANTISENSE MODULATION OF APOLIPOPROTEIN B EXPRESSION

COLON DISEASE TARGETS AND USES THEREOF

Conjugated antisense compounds and their use

TARGETED DISRUPTION OF A CSF1-DAP12 PATHWAY MEMBER GENE FOR THE TREATMENT OF NEUROPATHIC PAIN

Oligonucleotide having non-natural nucleotide at 5′-terminal thereof

METHODS AND COMPOSITIONS FOR TREATING AND DIAGNOSING DISEASES

Methods to monitor post-translational gene silencing activity in plant tissues/cell types relevant for pathogen entry, propagation or replication

Methods and Compositions for Selecting siRNA of Improved Functionality

Single-stranded nucleic acid molecule for inhibiting TGF-β1 expression

Fungal chromosome-end knockoff strategy

IMMUNOMODULATION BY CONTROLLING ELR+ PROINFLAMMATORY CHEMOKINE LEVELS WITH THE LONG NON-CODING RNA UMLILO

Compositions for modulating C9ORF72 expression

Poly oligomer compound with biocleavable conjugates

NUCLEIC ACID COMPLEX, METHOD FOR FORMING NUCLEIC ACID HYBRIDIZATION, PHARMACEUTICAL COMPOSITION, NUCLEIC ACID PROBE, AND COMPLEMENTARY-STRAND NUCLEIC ACID COMPLEX

Cationic sulfonamide amino lipids and amphiphilic zwitterionic amino lipids

Modified polycationic polymers

Combination therapies for inner ear sensory hair cell regeneration/replacement

Products for the delivery of therapeutic/diagnostic compounds to the heart

METHOD AND COMPOSITION FOR TARGETED DELIVERY OF THERAPEUTIC AGENTS

Plant regulatory elements and uses thereof

USE OF MICRORNA PRECURSORS AS DRUGS FOR INDUCING CD34-POSITIVE ADULT STEM CELL EXPANSION

Methods of using microRNA-141

RNA interference mediated inhibition of gene expression using chemically modified short interfering nucleic acid (siNA)

Methods for the prevention and the treatment of extracapillary glomerulonephritis

ANTISENSE OLIGONUCLEOTIDES FOR THE TREATMENT OF LEBER CONGENITAL AMAUROSIS

Antisense design

Antisense design

Methods and pharmaceutical compositions for treating human immunodeficiency virus type 1 (HIV-1) infections

Structurally designed shRNAs

Cell penetrating stapled peptide, manufacturing method therefor, and use thereof

Efficient delivery of therapeutic molecules in vitro and in vivo

Nucleic acid complexes

Patatin-like phospholipase domain containing 3 (PNPLA3) iRNA compositions and methods of use thereof

Compositions and methods of engineered CRISPR-CAS9 systems using split-nexus CAS9-associated polynucleotides

Compositions and methods of engineered CRISPR-Cas9 systems using split-nexus Cas9-associated polynucleotides

Methods and compositions for the activation of gamma-delta T-cells

ANTISENSE OLIGONUCLEOTIDES DIRECTED AGAINST CONNECTIVE TISSUE GROWTH FACTOR AND USES THEREOF

Preventing and treating inflammatory skin diseases

Nucleic acid molecules inducing RNA interference, and uses thereof

METHODS FOR TREATING NEURODEGENERATIVE DISEASES

Chiral library screen

Compounds and methods for the modulation of COMP

MALAT-1, A NON-CODING RNA, IS A TARGET FOR THE REGULATION OF LEARNING AND MEMORY

Use of a reverse-transcriptase inhibitor in the prevention and treatment of degenerative diseases

RNA hydrogel

RNA interference suppression of neurodegenerative diseases and methods of use

Methods for modulating ATRX-dependent gene repression

Genetically-modified cells comprising a modified human T cell receptor alpha constant region gene

Targeting Apolipoprotein E (APOE) in Neurologic Disease

Cationic lipid

TLR9 TARGETED CYTOTOXIC AGENTS

Methods for treating and/or limiting development of diabetes

Genetically-modified cells comprising a modified human T cell receptor alpha constant region gene

MIR-214 AS A DIAGNOSTIC AND PROGNOSTIC BIOMARKER SPECIFIC FOR ULCERATIVE COLITIS AND A MIR-214 INHIBITOR FOR TREATMENT OF SAME

Nanoparticle

Treatment of PAR4 related diseases by inhibition of natural antisense transcript to PAR4

Neutral nucleic acid ligands

Decoy oligonucleotides for the treatment of diseases

SELECTIVE ANTISENSE COMPOUNDS AND USES THEREOF

Selective Reactivation of Genes on the Inactive X Chromosome

RNA interference mediating small RNA molecules

Compositions and methods of nucleic acid-targeting nucleic acids

RNA-PROTEIN COMPLEX, AND RNA AND PROTEIN DELIVERY SYSTEM USING THE SAME

Sucrose ester based cationic gene vector and preparation method thereof

PH-sensitive peptides and their nanoparticles for drug delivery

Biotin complexes for treatment and diagnosis of Alzheimer'S disease

Methods, systems, and compositions relating to MiRNA-146a

Oligonucleotide compositions with enhanced efficiency

Albumin production and cell proliferation

DEAD GUIDES FOR CRISPR TRANSCRIPTION FACTORS

Compositions and methods for inhibiting expression of transthyretin

CRISPR enzymes and systems

Antisense nucleic acids

COMPOSITIONS AND METHODS TO CONTROL INSECT PESTS

Isolated Novel Nucleic Acid and Protein Molecules from Corn and Methods of Using Those Molecules to Generate Transgenic Plants with Enhanced Agronomic Traits

Oligonucleotide sequence for use in pathway engineering

Modulation of prekallikrein (PKK) expression

AGENT FOR TREATING FIBROSIS OF THE INTESTINE

MicroRNA-200 based approaches for modulating bone formation inhibition and bone regeneration

Microrna compositions and methods of making and using same

LncRNA and oncolytic adenovirus, and application thereof

miRNA transcriptome methods and compositions

CRISPR/CAS-related methods and compositions for treating sickle cell disease

Delivery of small interfering RNA and micro RNA through nanogels containing hydrophobic pseudo-peptides

Branched oligonucleotides

miRNA FOR TREATING CANCER AND FOR USE WITH ADOPTIVE IMMUNOTHERAPIES

Methods of treating transthyretin (TTR) mediated amyloidosis

Methods for characterizing alternatively or aberrantly spliced mRNA isoforms

Pharmaceutical composition for treatment of cancer comprising RNA oligonucleotide

METHODS FOR TREATING EYE DISORDERS

Method for controlling obesity using minimally invasive means

Hippo and dystrophin complex signaling in cardiomyocyte renewal

Microrna inhibitor system and methods of use thereof

Single-stranded nucleic acid molecule for regulating expression of gene having delivering function

Tetragalnac and peptide containing conjugates and methods for delivery of oligonucleotides

Antisense antiviral compounds and methods for treating a filovirus infection

ACC OX promoter identified by microarray analysis

Adeno-associated viral vectors for treating myocilin (MYOC) glaucoma

METHODS AND COMPOSITIONS FOR INHALATION DELIVERY OF CONJUGATED OLIGONUCLEOTIDE

POLARIZATION OF MACROPHAGES TO A HEALING PHENOTYPE BY CARDIOSPHERE-DERIVED CELLS AND BY THE EXOSOMES SECRETED BY SUCH CELLS

MiRNA and its diagnostic and therapeutic uses in diseases or conditions associated with melanoma, or in diseases or conditions associated with activated BRAF pathway

MicroRNA (miRNA) and downstream targets for diagnostic and therapeutic purposes

Method for treating neurodegenerative diseases

Nucleic acids related to MiR-29B-1-5P and uses thereof

ANTI-TUMOR THERAPY

RNA interference mediated inhibition of gene expression using chemically modified short interfering nucleic acid (siNA)

Organic compositions to treat HSF1-related diseases

Enhancing dermal wound healing by downregulating microRNA-26a

COMPOSITIONS AND METHODS FOR TREATING HEPATIC FIBROSIS

Method For Screening Interfering Molecules

Intergenic RNAS and methods for modulating gene expression and pathogenesis in

Set of polypeptides exhibiting nuclease activity or nickase activity with dependence on light or in presence of drug or suppressing or activating expression of target gene

RNA interference agents for p21 gene modulation

Methods and compositions for transducing lymphocytes and regulated expansion thereof

TREATMENT OF C9FTD/ALS BY TARGETING RNA EXPANDED REPEAT SEQUENCES

Neuroprotective molecules and methods of treating neurological disorders and inducing stress granules

MULTIPLE EXON SKIPPING COMPOSITIONS FOR DMD

Cardiosphere-derived cells and exosomes secreted by such cells in the treatment of muscular dystrophy

Compositions and methods to control insect pests

Compositions for enhancing targeted gene editing and methods of use thereof

Methods for genetic control of insect infestations in plants and compositions thereof

FSH nucleic acid molecules to control insect pests

Therapeutic compositions

Downregulating miR-132 for the treatment of lipid related disorders

Compositions for treating muscular dystrophy

TTV miRNA sequences as an early marker for the future development of cancer and as a target for cancer treatment and prevention

PHOSPHATIDYLINOSITOL-3-KINASE NUCLEIC ACIDS AND USES THEREOF

Compositions and methods for treating and preventing inflammation

Programmable polypeptide and nucleic acid nanoparticles

NUCLEIC ACID-POLYPEPTIDE COMPOSITIONS AND USES THEREOF

Molecular targets for the treatment of wounds, in particular chronic wounds

Methods and compositions for the treatment of cancer

Antisense design

Chimeric single-stranded antisense polynucleotides and double-stranded antisense agent

Modified double-stranded RNA agents

Methods Of Inhibiting Tumorigenesis In Colon Adenocarcinoma And Compositions Therefor

Methods of Inducing Exon Skipping

Cancer treatment and immune system regulation through FAT10 pathway inhibition

ALTERATION OF NEURONAL GENE EXPRESSION BY SYNTHETIC piRNAs AND BY ALTERATION OF piRNA FUNCTION

Chiral control

MODULATION OF APOLIPOPROTEIN C-III EXPRESSION

Compositions and methods for treating vascular disorders

METHODS AND COMPOSITIONS FOR THE SPECIFIC INHIBITION OF MYC BY DOUBLE-STRANDED RNA

Methods and compositions for treating leber congenital amaurosis

Triggering RNA interference with RNA-DNA and DNA-RNA nanoparticles

Lipid membrane structure for intracellular delivery of siRNA

Methods for identifying and treating invasive/metastatic breast cancers