ClassID:

109054

C12N15/1137 - page 6 - CPC Classification

Classification description:

Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor; Recombinant DNA-technology; DNA or RNA fragments; Modified forms thereof; Non-coding nucleic acids modulating the expression of genes, e.g. antisense oligonucleotides against enzymes

Recent Application in this class:
#1501
20190106699
2019-04-11

siRNA targeting LDHA

#1502
20190105341
2019-04-11

Compositions and Methods for Treating Alzheimer's Disease and Other Tauopathies

#1503
20190100759
2019-04-04

Compositions and methods for treating beta-hemoglobinopathies

#1504
20190099453
2019-04-04

Medicament for liver regeneration and for treatment of liver failure

#1505
20190091265
2019-03-28

MEDICAMENT FOR LIVER REGENERATION AND FOR TREATMENT OF LIVER FAILURE

#1506
20190091234
2019-03-28

GAMMA-SECRETASE INHIBITION REDUCE APOC3 LEVELS AND PLASMA TRIGLYCERIDES

#1507
20190091225
2019-03-28

Antihelminthic medications for pathogenic nematodes

#1508
20190091220
2019-03-28

TARGETING PARP1 FOR TREATMENT OF TSC AND CANCERS

#1509
20190091160
2019-03-28

Bacterially-derived, intact minicells that encompass plasmid-free functional nucleic acid for in vivo delivery to mammalian cells

#1510
20190085336
2019-03-21

Treatment and diagnosis of inflammatory disorders

#1511
20190085328
2019-03-21

In vivo gene silencing by chemically modified and stable siRNA

#1512
20190084965
2019-03-21

Amine cationic lipids and uses thereof

#1513
20190083523
2019-03-21

Methods and compositions for the activation of gamma-delta T-cells

#1514
20190078096
2019-03-14

Combination vectors and methods for treating cancer

#1515
20190071679
2019-03-07

ANTI-TUMOR THERAPY

#1516
20190071678
2019-03-07

Modulation of DYRK1B expression

#1517
20190071677
2019-03-07

Methods for treating hypercholesterolemia

#1518
20190064149
2019-02-28

Cancer examination method and examination kit

#1519
20190062746
2019-02-28

RNA interference mediated inhibition of gene expression using chemically modified short interfering nucleic acid (siNA)

#1520
20190062697
2019-02-28

Cell Differentiation Marker and its Uses

#1521
20190060239
2019-02-28

Technology for the Preparation of Microparticles

#1522
20190055564
2019-02-21

ANTISENSE OLIGONUCLEOTIDES FOR MODULATING HTRA1 EXPRESSION

#1523
20190055563
2019-02-21

POLYMERASE Q AS A TARGET IN HR-DEFICIENT CANCERS

#1524
20190054180
2019-02-21

Gene/carrier complex for preventing or treating inflammatory diseases

#1525
20190048360
2019-02-14

Double strand RNA-mediated RNA interference through feeding detrimental to larval (gypsy moth)

#1526
20190048351
2019-02-14

MODULATORS OF COMPLEMENT FACTOR B

#1527
20190046660
2019-02-14

Compositions and methods for genetically modifying myosin phosphatase target subunit (Mypt1) gene for lowering blood pressure

#1528
20190040435
2019-02-07

Decreasing lactate level and increasing polypeptide production by down regulating the expression of lactate dehydrogenase and pyruvate dehydrogenase kinase

#1529
20190040396
2019-02-07

Method of treating VEGF/VEGFR resistant prostate cancer by combining the therapy with RAC1 inhibitors

#1530
20190040395
2019-02-07

MODULATORS OF KLK3 ERNA

#1531
20190040393
2019-02-07

Managing Intercellular Communications

#1532
20190038538
2019-02-07

RNA complexes that inhibit melanin production

#1533
20190032146
2019-01-31

Compositions and methods for predicting response and resistance to CDK4/6 inhibition

#1534
20190032061
2019-01-31

RNAi-Mediated Inhibition of Tumor Necrosis Factor Alpha-Related Conditions

#1535
20190032059
2019-01-31

Gene vector

#1536
20190032058
2019-01-31

Inhibition of oxidative stress in atrial fibrillation

#1537
20190031775
2019-01-31

Compositions and methods comprising histidyl-tRNA synthetase splice variants having non-canonical biological activities

#1538
20190030064
2019-01-31

Methods of treating myelodysplastic syndrome

#1539
20190025307
2019-01-24

Methods to identify and treat subjects having corticosteroid-resistant inflammatory diseases

#1540
20190024089
2019-01-24

Interfering RNA molecules

#1541
20190024088
2019-01-24

Polynucleotide agents targeting factor XII (hageman factor) (F12) and methods of use thereof

#1542
20190022125
2019-01-24

Methods and compositions for increasing the suppressive function of regulatory T-cells (Tregs)

#1543
20190022099
2019-01-24

Methylene-tetrahydrofolate reductase isoform-based biomarker and method of use thereof

#1544
20190017051
2019-01-17

Oligonucleotide compositions with enhanced efficiency

#1545
20190015422
2019-01-17

Methods for treating brain metastases using combinations of anti-P13K and anti-mTOR agents

#1546
20190015416
2019-01-17

BTK INHIBITORS FOR TREATING NEUROBLASTOMA

#1547
20190010548
2019-01-10

Methods and materials for determining pain sensitivity and predicting and treating related disorders

#1548
20190010503
2019-01-10

SINGLE-STRANDED NUCLEIC ACID MOLECULE INHIBITING EXPRESSION OF PRORENIN GENE OR PRORENIN RECEPTOR GENE, AND USE THEREOF

#1549
20190010501
2019-01-10

Targeting WSB1 and pVHL to treat cancer

#1550
20190010497
2019-01-10

RNA INTERFERENCE MEDIATED INHIBITION OF GENE EXPRESSION USING CHEMICALLY MODIFIED SHORT INTERFERING NUCLEIC ACID (siNA)

#1551
20190008898
2019-01-10

Inhibition of Diacylglycerol Kinase to Augment Adoptive T cell Transfer

#1552
20190002885
2019-01-03

Anti-ADAM33 oligonucleotides and related methods

#1553
20190002884
2019-01-03

Methods of treating cancer by inhibition of DNA repair proteins using antisense based therapies

#1554
20190002880
2019-01-03

DOUBLE-STRANDED OLIGONUCLEOTIDES

#1555
20190002585
2019-01-03

CANCER TREATMENT METHODS AND COMPOSITIONS

#1556
20190002499
2019-01-03

Peptides and nanoparticles for intracellular delivery of molecules

#1557
20190000880
2019-01-03

IMMUNE EFFECTOR CELL THERAPIES WITH ENHANCED EFFICACY

#1558
20180371482
2018-12-27

Polypeptides having beta-xylosidase activity and polynucleotides encoding same

#1559
20180371005
2018-12-27

Modified nucleosides, analogs thereof and oligomeric compounds prepared therefrom

#1560
20180369396
2018-12-27

Targeted sensitization of non-del(5q) malignant cells

#1561
20180369274
2018-12-27

RNA interference agents for GST-π gene modulation

#1562
20180363008
2018-12-20

Methods and compositions to increase somatic cell nuclear transfer (SCNT) efficiency by removing histone H3-lysine trimethylation

#1563
20180362988
2018-12-20

Methods for reducing LRRK2 expression

#1564
20180362987
2018-12-20

Targeted augmentation of nuclear gene output

#1565
20180362978
2018-12-20

Compositions and Methods for Inhibition of Expression of Apolipoprotein C-III (APOC3) Genes

#1566
20180360927
2018-12-20

Enzymatic replacement therapy and antisense therapy for pompe disease

#1567
20180360843
2018-12-20

MAO inhibitors and their conjugates as therapeutics for the treatment of brain cancer

#1568
20180360819
2018-12-20

ANTI-INFLUENZA VIRUS AGENT AND SCREENING METHOD FOR ANTI-INFLUENZA VIRUS AGENT

#1569
20180355361
2018-12-13

Modulation of pre-MRNA using splice modulating oligonucleotides as therapeutic agents in the treatment of disease

#1570
20180355359
2018-12-13

METHODS FOR DETERMINING RESISTANCE TO ANTICANCER THERAPY AND COMPOSITION USED THEREFOR

#1571
20180355352
2018-12-13

INHIBITING GENE EXPRESSION WITH dsRNA

#1572
20180346915
2018-12-06

Pharmaceutical composition for inhibition of cancer cell metastasis including siRNA for ribosomal protein S3

#1573
20180338919
2018-11-29

AMPHOTERIC LIPOSOMES COMPRISING IMINO LIPIDS

#1574
20180334726
2018-11-22

Somatic mutations in ATRX in brain cancer

#1575
20180334665
2018-11-22

Methods and compositions for producing double allele knock outs

#1576
20180327801
2018-11-15

METHOD FOR PREPARING RECOMBINANT PROTEINS THROUGH REDUCTION OF rnpA GENE EXPRESSION

#1577
20180327765
2018-11-15

Guayule with increased rubber production and yield

#1578
20180327751
2018-11-15

siRNA compositions that specifically downregulate expression of a variant of the PNPLA3 gene and methods of use thereof for treating a chronic liver disease or alcoholic liver disease (ALD)

#1579
20180327750
2018-11-15

Methods and compositions for reducing immunosupression by tumor cells

#1580
20180327748
2018-11-15

RNA interference in skin indications

#1581
20180325992
2018-11-15

MODULATION OF AXON DEGENERATION

#1582
20180320182
2018-11-08

Methods and Compositions for Selecting siRNA of Improved Functionality

#1583
20180320180
2018-11-08

AGE-RELATED MACULAR DEGENERATION TREATMENT

#1584
20180320155
2018-11-08

Polypeptides having cellulolytic enhancing activity and polynucleotides encoding same

#1585
20180320132
2018-11-08

Agents and methods for treating and preventing seborrheic keratosis

#1586
20180318430
2018-11-08

Complex comprising RNAi molecule and N-acetylated chitosan

#1587
20180318428
2018-11-08

POLYAMINATED POLYGLUTAMIC ACID-CONTAINING COMPOUNDS AND USES THEREOF FOR DELIVERING OLIGONUCLEOTIDES

#1588
20180312929
2018-11-01

Methods and compositions related to T-cell activity

#1589
20180312867
2018-11-01

Identification and use of target genes for control of plant parasitic nematodes

#1590
20180312847
2018-11-01

Methods of treatment using antisense oligomers and conjugates targeting PCSK9

#1591
20180312846
2018-11-01

Manufacture of antisense oligomers and conjugates targeting PCSK9

#1592
20180312845
2018-11-01

MODULATORS OF DIACYGLYCEROL ACYLTRANSFERASE 2 (DGAT2)

#1593
20180312844
2018-11-01

TREATMENT FOR CANCER METASTASIS

#1594
20180312841
2018-11-01

RIG-I ligands and methods for producing them

#1595
20180312607
2018-11-01

Application of PCSK9 inhibitors in the preparation of drugs for the treatment of inflammatory immune diseases

#1596
20180312477
2018-11-01

Substituted thiazoles for preventing and/or treating cell or tissue necrosis

#1597
20180305698
2018-10-25

Pharmaceutical composition for preventing and treating metabolic disease comprising MKRN1 expression or activity inhibitor as an active ingredient

#1598
20180305697
2018-10-25

Compositions and methods for enhancing CRISPR activity by POLQ inhibition

#1599
20180305693
2018-10-25

Treatment of down syndrome gene related diseases by inhibition of natural antisense transcript to a down syndrome gene

#1600
20180305687
2018-10-25

Linkage modified oligomeric compounds

#1601
20180305674
2018-10-25

Polypeptides having beta-xylosidase activity and polynucleotides encoding same

#1602
20180303863
2018-10-25

Pharmaceutical Composition for Treating STK11-Mutation Cancer Using Cardiac Glycosides

#1603
20180303833
2018-10-25

Method of preventing or treating osteoporosis by neddylation inhibitor

#1604
20180298379
2018-10-18

SMALL INTERFERING RNA MODIFICATION METHOD BY COMBINING WITH ISONUCLEOSIDE MODIFICATION, TERMINAL PEPTIDE CONJUGATION AND CATIONIC LIPOSOMES, AND PREPARATION

#1605
20180296677
2018-10-18

Lipids and lipid compositions for the delivery of active agents

#1606
20180296638
2018-10-18

Compositions for treating heart disease by inhibiting the action of mAKAP-β

#1607
20180291381
2018-10-11

Interfering RNA molecules

#1608
20180291380
2018-10-11

USP30 INHIBITORS AND METHODS OF USE

#1609
20180291379
2018-10-11

Methods and compositions for the specific inhibition of glycolate oxidase (HAO1) by double-stranded RNA

#1610
20180282735
2018-10-04

PHARMACEUTICAL COMPOSITION FOR NEURODEGENERATIVE BRAIN DISEASE AND SCREENING METHOD FOR THE SAME

#1611
20180282734
2018-10-04

Methods and compositions for the treatment of head and neck cancer

#1612
20180282733
2018-10-04

Therapeutic agent for sarcopenia and metabolic diseases

#1613
20180282732
2018-10-04

Compositions and methods of treating amyotrophic lateral sclerosis (ALS)

#1614
20180282398
2018-10-04

Expression of Fc-containing proteins

#1615
20180273638
2018-09-27

LIN28- MEDIATED CONTROL OF LET-7 BIOGENESIS

#1616
20180273637
2018-09-27

Methods and compositions for treatment of atherosclerosis

#1617
20180265873
2018-09-20

Genetic or pharmacological reduction of PERK enhances cortical- and hippocampus-dependent cognitive function

#1618
20180264027
2018-09-20

Method for treating a degenerative neurological disorders comprising administering ASM inhibitor

#1619
20180258491
2018-09-13

BIOMARKERS ASSOCIATED WITH BRM INHIBITION

#1620
20180258433
2018-09-13

Renal selective inhibition of cytochrome P450 3A5

#1621
20180258426
2018-09-13

Compounds for inducing anti-tumor immunity and methods thereof

#1622
20180256729
2018-09-13

Conjugated antisense compounds and their use

#1623
20180256720
2018-09-13

Compositions and methods for treating HIV-associated neurocognitive disorders

#1624
20180251761
2018-09-06

Oligomeric compounds comprising bicyclic nucleotides and uses thereof

#1625
20180250323
2018-09-06

Compositions and methods for inhibiting expression of ADAMTS-5 and ADAM17

#1626
20180245084
2018-08-30

COMPOSITIONS AND METHODS FOR ENHANCED INTESTINAL ABSORPTION OF CONJUGATED OLIGOMERIC COMPOUNDS

#1627
20180245083
2018-08-30

RNA INTERFERENCE MEDIATED INHIBITION OF GENE EXPRESSION USING CHEMICALLY MODIFIED SHORT INTERFERING NUCLEIC ACID (siNA)

#1628
20180237783
2018-08-23

Methods and compositions of short small hairpin RNAS and microRNAS for wound healing

#1629
20180237778
2018-08-23

ANTISENSE DESIGN

#1630
20180237777
2018-08-23

ANTISENSE DESIGN

#1631
20180235210
2018-08-23

ANTISENSE COMPOSITIONS TARGETING ERWINIA SPECIES AND METHODS OF USING THE SAME

#1632
20180223289
2018-08-09

Modulation of TMPRSS6 expression

#1633
20180223288
2018-08-09

COMPOSITIONS AND METHODS FOR THE MODULATION OF DNA DAMAGE RESPONSES USING BAL1 AND BBAP

#1634
20180223287
2018-08-09

Fibrotic treatment

#1635
20180223286
2018-08-09

Interfering RNA molecules

#1636
20180222917
2018-08-09

Compositions and methods for treating leukemia

#1637
20180221494
2018-08-09

SITE-SPECIFIC DELIVERY OF NUCLEIC ACIDS BY COMBINING TARGETING LIGANDS WITH ENDOSOMOLYTIC COMPONENTS

#1638
20180221436
2018-08-09

Treatments of oxidative stress conditions

#1639
20180216156
2018-08-02

Compositions and methods for modulating ABHD2 activity

#1640
20180216116
2018-08-02

Antisense oligomers targeting PCSK9

#1641
20180216115
2018-08-02

Compositions and methods for inhibiting expression of the PCSK9 gene

#1642
20180216114
2018-08-02

XANTHINE DEHYDROGENASE (XDH) IRNA COMPOSITIONS AND METHODS OF USE THEREOF

#1643
20180216113
2018-08-02

METHODS FOR REDUCING PROTEOTOXICITY

#1644
20180216112
2018-08-02

PROCESS FOR INDUCING RESISTANCE TO DIPHTHERIA TOXIN IN HUMAN CELLS, PRODUCTS AND USES THEREOF

#1645
20180216111
2018-08-02

ANTISENSE-INDUCED EXON2 INCLUSION IN ACID ALPHA-GLUCOSIDASE

#1646
20180216104
2018-08-02

HSD17B13 variants and uses thereof

#1647
20180216084
2018-08-02

HSD17B13 variants and uses thereof

#1648
20180215797
2018-08-02

Regulatory Protein Deficient Trichoderma Cells and Methods of Use Thereof

#1649
20180214573
2018-08-02

Gene therapies for neurodegenerative disorders targeting ganglioside biosynthetic pathways

#1650
20180214474
2018-08-02

Methods and compositions for selecting siRNA of improved functionality

#1651
20180209963
2018-07-26

SCREENING METHOD FOR SELECTED AMINO-LIPID-CONTAINING COMPOSITIONS

#1652
20180208930
2018-07-26

TREATMENT OF LIPID TRANSPORT AND METABOLISM GENE RELATED DISEASES BY INHIBITION OF NATURAL ANTISENSE TRANSCRIPT TO A LIPID TRANSPORT AND METABOLISM GENE

#1653
20180208555
2018-07-26

Method of synthesis of an ionizable cationic lipid

#1654
20180201936
2018-07-19

Polynucleotide agents targeting patatin-like phospholipase domain containing 3 (PNPLA3) and methods of use thereof

#1655
20180201935
2018-07-19

Fidgetin-like 2 as a target to enhance wound healing

#1656
20180201934
2018-07-19

Methods and compositions for selecting siRNA of improved functionality

#1657
20180201933
2018-07-19

Compounds for inducing anti-tumor immunity and methods thereof

#1658
20180200374
2018-07-19

Amine-containing transfection reagents and methods for making and using same

#1659
20180195074
2018-07-12

Compositions and methods for inhibiting expression of RRM2 genes

#1660
20180195073
2018-07-12

Glucokinase (GCK) iRNA compositions and methods of use thereof

#1661
20180195072
2018-07-12

Nucleic acid molecules targeting superoxide dismutase 1 (SOD1)

#1662
20180195070
2018-07-12

Compositions and methods for inhibiting gene expression of LPA

#1663
20180193344
2018-07-12

Nanocarriers and their processing for diagnostics and therapeutics

#1664
20180187198
2018-07-05

METHODS AND COMPOSITIONS FOR TREATING A PROPROTEIN CONVERTASE SUBTILISIN KEXIN (PCSK9) GENE-ASSOCIATED DISORDER

#1665
20180179546
2018-06-28

Oligonucleotide compounds for treatment of preeclampsia and other angiogenic disorders

#1666
20180179545
2018-06-28

Reduction of lipase activity in product formulations

#1667
20180179524
2018-06-28

COMPOSITIONS AND METHODS FOR INHIBITING CELL PROLIFERATION

#1668
20180177786
2018-06-28

MONOAMINE OXIDASE INHIBITORS AND METHODS FOR TREATMENT AND DIAGNOSIS OF PROSTATE CANCER

#1669
20180171305
2018-06-21

Use of phospholipid scramblase inhibitors for modulating inflammatory immune responses

#1670
20180171028
2018-06-21

Afucosylated protein, cell expressing said protein and associated methods

#1671
20180170865
2018-06-21

Ionizable cationic lipid for RNA delivery

#1672
20180163273
2018-06-14

Breast cancer biomarkers and methods of using same

#1673
20180163210
2018-06-14

Compositions and methods for controlling vasculature

#1674
20180163209
2018-06-14

MODULATION OF DYSTROPHIA MYOTONICA-PROTEIN KINASE (DMPK) EXPRESSION

#1675
20180163203
2018-06-14

Compositions and methods for delivery of a polynucleotide into a plant

#1676
20180153932
2018-06-07

METHOD FOR MAINTAINING INCREASED INTRACELLULAR p53 LEVEL, INDUCED BY PLATINUM-BASED ANTICANCER DRUG, AND APPLICATION THEREOF

#1677
20180148738
2018-05-31

CNS TARGETING AAV VECTORS AND METHODS OF USE THEREOF

#1678
20180148722
2018-05-31

Dual Targeting siRNA Agents

#1679
20180148719
2018-05-31

Delivering CRISPR therapeutics with lipid nanoparticles

#1680
20180147296
2018-05-31

CARBON MATERIAL DELIVERY SYSTEMS AND METHODS

#1681
20180142008
2018-05-24

Dynamin 2 inhibitor for the treatment of Duchenne's muscular dystrophy

#1682
20180135129
2018-05-17

Methods for treating Parkinson's disease

#1683
20180135058
2018-05-17

Cell death inducing agent for cells having BRAF gene mutation, growth suppressing agent for same cells and pharmaceutical composition for therapy of diseases caused by growth defect of same cells

#1684
20180127783
2018-05-10

CRISPR-related methods and compositions with governing gRNAS

#1685
20180127759
2018-05-10

DYNAMIC GENOME ENGINEERING

#1686
20180127758
2018-05-10

Modulation of nuclear-retained RNA

#1687
20180127453
2018-05-10

2′-arabino-fluorooligonucleotide N3′˜P5′ phosphoramidates: their synthesis and use

#1688
20180119168
2018-05-03

Negative regulator of plant immunity against nematodes

#1689
20180119152
2018-05-03

Antisense compounds targeting genes associated with cystic fibrosis

#1690
20180119147
2018-05-03

RNA amidates and thioamidates for RNAi

#1691
20180119144
2018-05-03

Methods and compositions for selecting siRNA of improved functionality

#1692
20180118775
2018-05-03

Nucleoside-lipid compounds with pH-sensitive dialkylorthoester chains and their use for transportation or vectorization of at least one therapeutic agent

#1693
20180117173
2018-05-03

Method of targeting senescent cells

#1694
20180110788
2018-04-26

METHODS AND COMPOSITIONS FOR INHIBITING THE GROWTH AND/OR PROLIFERATION OF MYC-DRIVEN TUMOR CELLS

#1695
20180105860
2018-04-19

MUTEINS OF THE PYRROLINE-5-CARBOXYLATE REDUCTASE 1

#1696
20180105817
2018-04-19

Compounds and methods for modulating TMPRSS6 expression

#1697
20180105816
2018-04-19

Therapeutic UNA oligomers and uses thereof

#1698
20180105493
2018-04-19

Cationic lipid

#1699
20180104349
2018-04-19

Novel linker, preparation method, and application thereof

#1700
20180104342
2018-04-19

Lipid compositions

#1701
20180100167
2018-04-12

Methods for enriching gene-targeted cells

#1702
20180100156
2018-04-12

Modulation of pre-mRNA using splice modulating oligonucleotides as therapeutic agents in the treatment of disease

#1703
20180100154
2018-04-12

RNA interference mediated inhibition of prolyl hydroxylase domain 2 (PHD2) gene expression using short interfering nucleic acid (siNA)

#1704
20180094266
2018-04-05

Antisense compounds targeting leucine-rich repeat kinase 2 (LRRK2) for the treatment of parkinsons disease

#1705
20180092990
2018-04-05

Polynucleotide agents targeting hydroxyacid oxidase (glycolate oxidase, HAO1) and methods of use thereof

#1706
20180092920
2018-04-05

METHOD FOR TREATING TAU PROTEIN-MEDIATED DEGENERATIVE NEURONAL DISEASE

#1707
20180092894
2018-04-05

TREATMENT OF EOSINOPHILIC INFLAMMATORY DISEASE

#1708
20180092848
2018-04-05

NOVEL LIPID FORMULATIONS FOR NUCLEIC ACID DELIVERY

#1709
20180087058
2018-03-29

TMPRSS6 iRNA COMPOSITIONS AND METHODS OF USE THEREOF

#1710
20180087057
2018-03-29

Methods of treating cancer

#1711
20180087056
2018-03-29

Oligonucleotide compositions with enhanced efficiency

#1712
20180087037
2018-03-29

BGL7 Beta-Glucosidase and Nucleic Acids Encoding the Same

#1713
20180085390
2018-03-29

Polyvalent RNA-nanoparticle compositions

#1714
20180085312
2018-03-29

NOVEL LIPID FORMULATIONS FOR NUCLEIC ACID DELIVERY

#1715
20180073084
2018-03-15

METHOD FOR PREDICTING RESPONSIVENESS TO PHOSPHATIDYLSERINE SYNTHASE 1 INHIBITOR

#1716
20180073021
2018-03-15

Recombinant protein-based method for the delivery of silencer RNA to target the brain

#1717
20180071397
2018-03-15

NOVEL LIPID FORMULATIONS FOR DELIVERY OF THERAPEUTIC AGENTS TO SOLID TUMORS

#1718
20180066327
2018-03-08

Methods to Accelerate Wound Healing in Diabetic Subjects

#1719
20180066269
2018-03-08

Promoter and uses thereof

#1720
20180066266
2018-03-08

EML4-ALK FUSION GENE

#1721
20180064746
2018-03-08

Assay for telomere length regulators

#1722
20180057888
2018-03-01

KUB5/HERA AS A DETERMINANT OF SENSITIVITY TO DNA DAMAGE

#1723
20180057815
2018-03-01

siRNA sequence-independent modification formats for reducing off-target phenotypic effects in RNAi, and stabilized forms thereof

#1724
20180055811
2018-03-01

Methods of treating an overweight subject

#1725
20180051289
2018-02-22

THERAPEUTICS AND METHODS OF TREATING FATTY LIVER DISEASE

#1726
20180050011
2018-02-22

Inflammasome activation in myelodysplastic syndromes

#1727
20180045740
2018-02-15

METHOD OF DIAGNOSIS, PROGNOSIS OR TREATMENT OF NEURODEGENERATIVE DISEASES

#1728
20180044681
2018-02-15

Methods of treating cancer harboring hemizygous loss of TP53

#1729
20180037895
2018-02-08

COMPOSITIONS AND METHODS FOR EFFICACIOUS AND SAFE DELIVERY OF SIRNA USING SPECIFIC CHITOSAN-BASED NANOCOMPLEXES

#1730
20180037893
2018-02-08

Low molecular weight cyclic amine containing cationic lipids for oligonucleotide delivery

#1731
20180037886
2018-02-08

Compositions and methods for inhibiting expression of the ALAS1 gene

#1732
20180030452
2018-02-01

TARGETING OLIGONUCLEOTIDES AND USES THEREOF TO MODULATE GENE EXPRESSION

#1733
20180030451
2018-02-01

Methods for treating aging and skin disorders using nucleic acids targeting Tyr or MMP1

#1734
20180028456
2018-02-01

Delivering functional nucleic acids to mammalian cells via bacterially-derived, intact minicells

#1735
20180028449
2018-02-01

Technology for the Preparation of Microparticles

#1736
20180023087
2018-01-25

Screening Method For Compound Having Obesity Preventive Or Therapeutic Activity

#1737
20180023086
2018-01-25

Compositions and methods for inhibiting gene expression of factor XII

#1738
20180022824
2018-01-25

COMPLEMENT INHIBITION FOR IMPROVED NERVE REGENERATION

#1739
20180022779
2018-01-25

Compositions and methods for regulating arterial tone

#1740
20180021449
2018-01-25

Antisense conjugates for decreasing expression of DMPK

#1741
20180021447
2018-01-25

Lipid Nanoparticle Compositions and Methods of Making and Methods of Using the Same

#1742
20180021323
2018-01-25

FLIP - A SELECTIVE MOLECULAR TARGET OF SENESCENT CELLS

#1743
20180016579
2018-01-18

Methods for the treatment of Leber congenital amaurosis

#1744
20180016294
2018-01-18

Oligonucleotide compositions and methods of making the same

#1745
20180016293
2018-01-18

Oligonucleotide compositions and methods of making the same

#1746
20180010132
2018-01-11

INHIBITION OF PRMT5 TO TREAT MTAP-DEFICIENCY-RELATED DISEASES

#1747
20180010129
2018-01-11

Compositions and methods to promote erythropoiesis

#1748
20180010127
2018-01-11

METHOD OF ENHANCING MIR-185 EXPRESSION TO REDUCE LOW DENSITY LIPOPROTEIN/CHOLESTEROL ACCUMULATION IN A CELL

#1749
20180009837
2018-01-11

Compounds and methods for the modulation of proteins

#1750
20180002724
2018-01-04

Agents for improved delivery of nucleic acids to eukaryotic cells

#1751
20180002702
2018-01-04

METHODS AND COMPOSITIONS FOR TREATING MALIGNANT TUMORS ASSOCIATED WITH KRAS MUTATION

#1752
20180002701
2018-01-04

Antisense oligonucleotides for modulating HTRA1 expression

#1753
20180002700
2018-01-04

Pharmaceutical composition for preventing or treating diabetic complications and screening method for preventive or therapeutic agent for diabetic complications

#1754
20180002699
2018-01-04

Compositions and methods for reactivating latent immunodeficiency virus

#1755
20180002692
2018-01-04

Sequence Specific and Organism Specific Antimicrobials and Related Materials and Methods

#1756
20180000830
2018-01-04

INHIBITORS OF HEMOPOIETIC CELL KINASE (P-59-HCK) AND THEIR USE IN THE TREATMENT OF INFLUENZA INFECTION

#1757
20180000822
2018-01-04

Use of RNAI Inhibiting PARP Activity for the Manufacture of a Medicament for the Treatment of Cancer

#1758
20180000817
2018-01-04

TREATMENT OF HUTCHINSON-GILFORD PROGERIA SYNDROME AND DISEASES RELATED TO VASCULAR AGEING

#1759
20170369888
2017-12-28

ADAM12 inhibitors and their use against inflammation-induced fibrosis

#1760
20170369887
2017-12-28

Therapeutic compositions for breast cancer containing protein kinase D1 inhibitor

#1761
20170369841
2017-12-28

Method for modifying T cell population

#1762
20170362622
2017-12-21

Polypeptides having cellulolytic enhancing activity and polynucleotides encoding same

#1763
20170362595
2017-12-21

Methods and materials for treating cancer

#1764
20170362594
2017-12-21

TMPRSS6 iRNA compositions and methods of use thereof

#1765
20170362593
2017-12-21

USE OF RAD18 INHIBITORS IN THE TREATMENT OF TUMORS

#1766
20170362592
2017-12-21

Modulation of UBE3A-ATS expression

#1767
20170355996
2017-12-14

Treatment of RNASE H1 related diseases by inhibition of natural antisense transcript to RNASE H1

#1768
20170349911
2017-12-07

CNS targeting AAV vectors and methods of use thereof

#1769
20170349904
2017-12-07

Methods and Compositions for Selecting siRNA of Improved Functionality

#1770
20170349903
2017-12-07

siRNA compositions that specifically downregulate expression of a variant of the PNPLA3 gene and methods of use thereof for treating a chronic liver disease or alcoholic liver disease (ALD)

#1771
20170348266
2017-12-07

Inhibition of proline catabolism for the treatment of cancer and other therapeutic applications

#1772
20170348234
2017-12-07

METHOD AND COMPOSITION FOR TARGETED DELIVERY OF THERAPEUTIC AGENTS

#1773
20170342454
2017-11-30

Method for preparing recombinant proteins through reduction of rnpA gene expression

#1774
20170342420
2017-11-30

METHODS FOR TREATING HYPERCHOLESTEROLEMIA

#1775
20170342413
2017-11-30

Antisense design

#1776
20170342412
2017-11-30

Antisense design

#1777
20170340661
2017-11-30

Patatin-like phospholipase domain containing 3 (PNPLA3) iRNA compositions and methods of use thereof

#1778
20170336425
2017-11-23

PIP2 AS A MARKER FOR HDL FUNCTION AND CARDIOVASCULAR DISEASE RISK

#1779
20170335011
2017-11-23

Bruton's tyrosine kinase as anti-cancer drug target

#1780
20170334852
2017-11-23

Cationic lipid

#1781
20170333490
2017-11-23

Targeting epigenetic regulators using a bacterial delivery system

#1782
20170327846
2017-11-16

Methods and compositions to increase somatic cell nuclear transfer (SCNT) efficiency by removing histone H3-lysine trimethylation

#1783
20170327827
2017-11-16

ADIPOCYTE-SPECIFIC CONSTRUCTS AND METHODS FOR INHIBITING PLATELET-TYPE 12 LIPOXYGENASE EXPRESSION

#1784
20170325708
2017-11-16

Methods and compositions for cell-proliferation-related disorders

#1785
20170321219
2017-11-09

Oligonucleotide compositions with enhanced efficiency

#1786
20170321218
2017-11-09

Factor XIa-specific aptamers

#1787
20170321217
2017-11-09

Antisense oligonucleotide for splicing adjustment of mutant dopa decarboxylase gene and using method thereof

#1788
20170321216
2017-11-09

Modulation of AGPAT5 expression

#1789
20170320964
2017-11-09

Modulators of ACYL-COA lysocardiolipin acyltransferase 1 (ALCAT1) and uses thereof

#1790
20170314040
2017-11-02

Fusarium chitin synthase gene chs3b and the use thereof

#1791
20170314029
2017-11-02

Oligonucleotide sequence for use in pathway engineering

#1792
20170314028
2017-11-02

Modulatory polynucleotides

#1793
20170314027
2017-11-02

INCREASING ATOH1 LIFE TO DRIVE SENSORINEURAL HAIR CELL DIFFERENTIANTION

#1794
20170314026
2017-11-02

Modulation of prekallikrein (PKK) expression

#1795
20170312318
2017-11-02

Methods and compositions for in vivo induction of pancreatic beta cell formation

#1796
20170306333
2017-10-26

Methods and compositions for the specific inhibition of glycolate oxidase (HAO1) by double-stranded RNA

#1797
20170306332
2017-10-26

Therapeutic inhibition of lactate dehydrogenase and agents therefor

#1798
20170306328
2017-10-26

Method for controlling obesity using minimally invasive means

#1799
20170304446
2017-10-26

Compositions and methods for inhibition of HAO1 (Hydroxyacid Oxidase 1 (Glycolate Oxidase)) gene expression

#1800
20170298421
2017-10-19

Method for identification of sensitivity of a patient to telomerase inhibition therapy