ClassID:

109162

C12N2310/315 - page 10 - CPC Classification

Classification description:

Structure or type of the nucleic acid; Chemical structure of the backbone Phosphorothioates

Recent Application in this class:
#2701
20160333341
2016-11-17

MicroRNA compounds and methods for modulating miR-21 activity

#2702
20160331836
2016-11-17

Chiral nucleic acid adjuvant having antitumor effect and antitumor agent

#2703
20160331835
2016-11-17

Chiral nucleic acid adjuvant having anti-allergic activity, and anti-allergic agent

#2704
20160326527
2016-11-10

Compositions and methods for treatment of prostate and other cancers

#2705
20160326526
2016-11-10

Oligonucleotide-based inhibitors comprising locked nucleic acid motif

#2706
20160319283
2016-11-03

Methods for treatment of alport syndrome

#2707
20160319278
2016-11-03

FULLY STABILIZED ASYMMETRIC SIRNA

#2708
20160317671
2016-11-03

Cell penetrating conjugates and methods of use thereof

#2709
20160312217
2016-10-27

Modulation of huntingtin expression

#2710
20160311845
2016-10-27

Nucleotide derivative or salt thereof, nucleotide-derived 5′-phosphate ester or salt thereof, nucleotide-derived 3′-phosphoramidite compound or salt thereof, and polynucleotide

#2711
20160304880
2016-10-20

SiRNA and their use in methods and compositions for inhibiting the expression of the ORAI1 gene

#2712
20160304877
2016-10-20

COMPOUNDS AND METHODS FOR MODULATION OF DYSTROPHIA MYOTONICA-PROTEIN KINASE (DMPK) EXPRESSION

#2713
20160304876
2016-10-20

Antisense oligonucleotides (ODN) against SMAD7 and uses thereof in medical field

#2714
20160304875
2016-10-20

METHODS FOR TREATMENT OF WOUND HEALING UTILIZING CHEMICALLY MODIFIED OLIGONUCLEOTIDES

#2715
20160304871
2016-10-20

Compositions for modulating C9ORF72 expression

#2716
20160304870
2016-10-20

Methods and compositions for the specific inhibition of transthyretin (TTR) by double-stranded RNA

#2717
20160304868
2016-10-20

Compositions of asymmetric interfering RNA and uses thereof

#2718
20160304864
2016-10-20

MEANS AND METHODS FOR COUNTERACTING MUSCLE DISORDERS

#2719
20160298124
2016-10-13

Complement component iRNA compositions and methods of use thereof

#2720
20160298123
2016-10-13

RNA INTERFERENCE MEDIATED INHIBITION OF PROLYL HYDROXYLASE DOMAIN 2 (PHD2) GENE EXPRESSION USING SHORT INTERFERING NUCLEIC ACID (SINA)

#2721
20160298121
2016-10-13

Targeted augmentation of nuclear gene output

#2722
20160298118
2016-10-13

Aptamers to PDGF and VEGF and their use in treating PDGF and VEGF mediated conditions

#2723
20160289759
2016-10-06

Treatment of pyrroline-5-carboxylate reductase 1 (PYCR1) related disease by inhibition of natural antisense transcript to PYCR1

#2724
20160289677
2016-10-06

APOB Antisense Conjugate Compounds

#2725
20160289675
2016-10-06

Guide RNA with chemical modifications

#2726
20160281091
2016-09-29

METHODS AND COMPOSITIONS FOR THE SPECIFIC INHIBITION OF MYC BY DOUBLE-STRANDED RNA

#2727
20160281089
2016-09-29

PREVENTION OF VIRAL INFECTIVITY

#2728
20160281087
2016-09-29

Modulation of T cell signaling threshold and T cell sensitivity to antigens

#2729
20160273037
2016-09-22

Treatment of colony-stimulating factor 3 (CSF3) related diseases by inhibition of natural antisene transcript to CSF3

#2730
20160272979
2016-09-22

Organic compositions to treat beta-ENaC-related diseases

#2731
20160272978
2016-09-22

Compositions and methods for inhibiting gene expression of factor XII

#2732
20160272974
2016-09-22

Compositions and methods for inhibiting JC virus (JCV)

#2733
20160272971
2016-09-22

Disulfide-containing alkyne linking agents

#2734
20160272968
2016-09-22

Targeting microRNA-26a/b for the treatment of neurodegenerative disease

#2735
20160264972
2016-09-15

Compositions and Methods for Inhibiting Expression of a Gene from the Ebola Virus

#2736
20160264968
2016-09-15

MODIFIED iRNA AGENTS

#2737
20160264967
2016-09-15

OLIGONUCLEOTIDE COMPRISING AN INOSINE FOR TREATING DMD

#2738
20160264966
2016-09-15

Compositions and methods for inhibiting expression of the LECT2 gene

#2739
20160264964
2016-09-15

RNA interference mediated inhibition of gene expression using short interfering nucleic acids (siNA)

#2740
20160264963
2016-09-15

Compositions and Methods for Inhibiting Expression of Transthyretin

#2741
20160263253
2016-09-15

Suicide contrast agents targeting HIV reservoirs for theranostic eradication

#2742
20160257962
2016-09-08

RNA INTERFERENCE MEDIATED INHIBITION OF ISOCITRATE DEHYDROGENASE (IDH1) GENE EXPRESSION

#2743
20160257954
2016-09-08

SERPINC1 iRNA COMPOSITIONS AND METHODS OF USE THEREOF

#2744
20160251658
2016-09-01

MODULATION OF EXON RECOGNITION IN PRE-MRNA BY INTERFERING WITH THE SECONDARY RNA STRUCTURE

#2745
20160251657
2016-09-01

MicroRNA compounds and methods for modulating miR-122

#2746
20160251656
2016-09-01

MicroRNAs modulating the effect of glucocorticoid signaling

#2747
20160251655
2016-09-01

Compositions for modulating C9ORF72 expression

#2748
20160244768
2016-08-25

Method for reducing circulating leukocytes in a human subject

#2749
20160244767
2016-08-25

Antisense compounds targeting genes associated with cystic fibrosis

#2750
20160244766
2016-08-25

Compositions and methods for inhibiting expression of the ALAS1 gene

#2751
20160244765
2016-08-25

Reduced size self-delivering RNAI compounds

#2752
20160244763
2016-08-25

Complement component C5 iRNA compositions and methods of use thereof

#2753
20160244762
2016-08-25

Reducing intron retention

#2754
20160244760
2016-08-25

RNA interference mediated inhibition of gene expression using chemically modified short interfering nucleic acid (siNA)

#2755
20160244757
2016-08-25

Compositions and methods for modulating neuronal excitability and motor behavior

#2756
20160244753
2016-08-25

MicroRNA compounds and methods for modulating miR-21 activity

#2757
20160237439
2016-08-18

Modular RNA regulators and methods

#2758
20160237434
2016-08-18

Modulation of apolipoprotein C-III expression

#2759
20160237432
2016-08-18

METHODS FOR MODULATING EXPRESSION OF C9ORF72 ANTISENSE TRANSCRIPT

#2760
20160237427
2016-08-18

Tau antisense oligomers and uses thereof

#2761
20160230174
2016-08-11

TOLEROGENIC DENDRITIC CELLS TO TREAT INFLAMMATORY BOWEL DISEASE

#2762
20160230172
2016-08-11

COMPOSITIONS FOR MODULATING EXPRESSION OF C9ORF72 ANTISENSE TRANSCRIPT

#2763
20160222389
2016-08-04

MODULATORS OF COMPLEMENT FACTOR B

#2764
20160222383
2016-08-04

Antisense compositions and methods of making and using same

#2765
20160215292
2016-07-28

Notch 1 specific siRNA molecule

#2766
20160215291
2016-07-28

Nucleic acids and methods for the treatment of Pompe disease

#2767
20160208264
2016-07-21

Antisense-induced exon2 inclusion in acid alpha-glucosidase

#2768
20160208260
2016-07-21

Complex containing oligonucleotide having immunopotentiating activity and use thereof

#2769
20160208259
2016-07-21

Targeting microRNAs for metabolic disorders

#2770
20160208258
2016-07-21

miR-92 inhibitors and uses thereof

#2771
20160194645
2016-07-07

Compositions and methods for inhibiting expression of mutant EGFR gene

#2772
20160194642
2016-07-07

SPHERICAL NUCLEIC ACID-BASED CONSTRUCTS AS IMMUNOREGULATORY AGENTS

#2773
20160194638
2016-07-07

Compounds and methods for modulating target nuclear and sub-nuclear nucleic acid molecules in cells and animals

#2774
20160194637
2016-07-07

Compounds and methods for modulating target nuclear and sub-nuclear nucleic acid molecules in cells and animals

#2775
20160194636
2016-07-07

MODULATION OF EXON RECOGNITION IN PRE-MRNA BY INTERFERING WITH THE SECONDARY RNA STRUCTURE

#2776
20160194349
2016-07-07

Compositions and methods for modulating angiopoietin-like 3 expression

#2777
20160186185
2016-06-30

Modified nucleosides, analogs thereof and oligomeric compounds prepared therefrom

#2778
20160186180
2016-06-30

Angiopoietin-like 3 (ANGPTL3) iRNA compositions and methods of use thereof

#2779
20160186179
2016-06-30

Methods and compositions for modulating gene expression using oligonucleotide based drugs administered in vivo or in vitro

#2780
20160186174
2016-06-30

SUBSTITUTED MORPHOLINO COMPOUNDS ANALOGS THEREOF AND OLIGOMERIC COMPOUNDS PREPARED THEREFROM

#2781
20160186173
2016-06-30

C-myc antisense oligonucleotides and methods for using the same to treat cell-proliferative disorders

#2782
20160186172
2016-06-30

Compositions and methods for inhibiting hepcidin antimicrobial peptide (HAMP) or HAMP-related gene expression

#2783
20160177313
2016-06-23

Compositions and methods for increasing erythropoietin (EPO) production

#2784
20160177307
2016-06-23

PDGF and VEGF aptamers having improved stability and their use in treating PDGF and VEGF mediated diseases and disorders

#2785
20160177306
2016-06-23

Antisense oligonucleotides (ODN) against Smad7 and uses thereof in medical field

#2786
20160177304
2016-06-23

CRISPR-based compositions and methods of use

#2787
20160177302
2016-06-23

MicroRNA (miRNA) and downstream targets for diagnostic and therapeutic purposes

#2788
20160168570
2016-06-16

MODULATION OF EXON RECOGNITION IN PRE-MRNA BY INTERFERING WITH THE SECONDARY RNA STRUCTURE

#2789
20160168568
2016-06-16

Treatment of Adiponectin (ADIPOQ) related diseases by inhibition of natural antisense transcript to an Adiponectin (ADIPOQ)

#2790
20160160217
2016-06-09

COMPOSITIONS AND METHODS FOR CHARACTERIZING AND TREATING MUSCULAR DYSTROPHY

#2791
20160152983
2016-06-02

RIG-I ligands and methods for producing them

#2792
20160152974
2016-06-02

Compounds and methods for modulating apolipoprotein C-III expression for improving a diabetic profile

#2793
20160145629
2016-05-26

TMPRSS6 iRNA compositions and methods of use thereof

#2794
20160145626
2016-05-26

Compositions and methods for inhibiting expression of TMPRSS6 gene

#2795
20160145625
2016-05-26

Dnazyme for silencing the expression of EGFR

#2796
20160145622
2016-05-26

Dengue virus-specific siRNA, double helix oligo-RNA structure comprising siRNA, and composition for suppressing proliferation of dengue virus comprising RNA structure

#2797
20160145620
2016-05-26

Oligomers with improved off-target profile

#2798
20160145617
2016-05-26

Compositions for modulating Tau expression

#2799
20160145614
2016-05-26

Double-stranded agents for delivering therapeutic oligonucleotides

#2800
20160145609
2016-05-26

Micro-RNA family that modulates fibrosis and uses thereof

#2801
20160145608
2016-05-26

Micro-RNA family that modulates fibrosis and uses thereof

#2802
20160145607
2016-05-26

Micro-RNA family that modulates fibrosis and uses thereof

#2803
20160138029
2016-05-19

Antisense-oligonucleotides as inhibitors of TGF-R signaling

#2804
20160138023
2016-05-19

Treatment of brain derived neurotrophic factor (BDNF) related diseases by inhibition of natural antisense transcript to BDNF

#2805
20160138014
2016-05-19

ANTISENSE COMPOUNDS AND USES THEREOF

#2806
20160136195
2016-05-19

Use of HMGA-targeted phosphorothioate DNA aptamers to suppress carcinogenic activity and increase sensitivity to chemotherapy agents in human cancer cells

#2807
20160130586
2016-05-12

Preventive or therapeutic agent for fibrosis

#2808
20160130584
2016-05-12

Treatment of alpha-L-iduronidase (IDUA) related diseases by inhibition of natural antisense transcript to IDUA

#2809
20160130583
2016-05-12

Double-stranded antisense nucleic acid with exon-skipping effect

#2810
20160130582
2016-05-12

OLIGONUCLEOTIDE MODULATORS OF B-CELL CLL/LYMPHOMA 11A (BCL11A) AND USES THEREOF

#2811
20160130578
2016-05-12

Reduced size self-delivering RNAi compounds

#2812
20160122761
2016-05-05

COMPOSITIONS AND METHODS FOR MODULATION OF TARGET NUCLEIC ACIDS

#2813
20160122760
2016-05-05

COMPOSITIONS AND METHODS FOR MODULATING FOXP3 EXPRESSION

#2814
20160122759
2016-05-05

Dosages and methods for delivering lipid formulated nucleic acid molecules

#2815
20160115476
2016-04-28

Compositions and methods for inhibiting expression of the ALAS1 gene

#2816
20160115218
2016-04-28

Anti-sense oligonucleotides targeted against exon 9 of IL-23R-alpha gene and method of using same to induce exon skipping and to treat inflammatory bowel diseases

#2817
20160108401
2016-04-21

Complement component C5 iRNA compositions and methods of use thereof

#2818
20160108399
2016-04-21

Modulation of HSP47 expression

#2819
20160108398
2016-04-21

Hydrophobically modified antisense oligonucleotides comprising a ketal group

#2820
20160108397
2016-04-21

Targeting microRNAs for the treatment of fibrosis

#2821
20160108395
2016-04-21

CHIMERIC SINGLE-STRANDED ANTISENSE POLYNUCLEOTIDES AND DOUBLE-STRANDED ANTISENSE AGENT

#2822
20160102312
2016-04-14

Compositions and methods for inhibiting expression of the HAMP gene

#2823
20160090599
2016-03-31

Treatment of delta-like 1 homolog (DLK1) related diseases by inhibition of natural antisense transcript to DLK1

#2824
20160090598
2016-03-31

Antisense compounds and uses thereof

#2825
20160090596
2016-03-31

Compositions and methods for modulating apolipoprotein (a) expression

#2826
20160090595
2016-03-31

Compositions and methods for modulating apolipoprotein C-III expression

#2827
20160081944
2016-03-24

Oligonucleotide lipid nanoparticle compositions, methods of making and methods of using the same

#2828
20160076040
2016-03-17

Therapeutic compositions

#2829
20160076034
2016-03-17

RNA interference mediated inhibition of hepatitis B virus (HBV) gene expression using short interfering nucleic acid (siNA)

#2830
20160076032
2016-03-17

Compositions and methods

#2831
20160076031
2016-03-17

Phosphorous-linked oligomeric compounds and their use in gene modulation

#2832
20160076030
2016-03-17

Compositions and methods for modulating HBV expression

#2833
20160068846
2016-03-10

Modulation of androgen receptor expression

#2834
20160068845
2016-03-10

Modulation of dystrophia myotonica-protein kinase (DMPK) expression

#2835
20160068842
2016-03-10

miR-29 mimics and uses thereof

#2836
20160068840
2016-03-10

RNAI MODULATION OF SCAP AND THERAPEUTIC USES THEREOF

#2837
20160067355
2016-03-10

Composition for delivery of genetic material

#2838
20160060626
2016-03-03

MODULATION OF ANGIOPOIETIN-LIKE 3 EXPRESSION

#2839
20160060625
2016-03-03

MODULATION OF APOLIPOPROTEIN CIII (APOCIII) EXPRESSION

#2840
20160053269
2016-02-25

RNA interference mediated inhibition of gene expression using chemically modified short interfering nucleic acid (siNA)

#2841
20160053262
2016-02-25

Method for efficient exon (44) skipping in duchenne muscular dystrophy and associated means

#2842
20160053256
2016-02-25

COMPOSITIONS AND THEIR USES DIRECTED TO HUNTINGTIN

#2843
20160053254
2016-02-25

Treatment of genetic disorders associated with DNA repeat instability

#2844
20160046945
2016-02-18

Modulation of hepatitis B virus (HBV) expression

#2845
20160046944
2016-02-18

Aptamer to IL-17 and use thereof

#2846
20160046942
2016-02-18

Treatment of sex hormone binding globulin (SHBG) related diseases by inhibition of natural antisense transcript to SHBG

#2847
20160046941
2016-02-18

Targeting microRNAs for the treatment of liver cancer

#2848
20160046940
2016-02-18

Targeting microRNAs for metabolic disorders

#2849
20160046931
2016-02-18

Methods for enhancing utrophin production via inhibition of microRNA

#2850
20160032289
2016-02-04

Oral delivery of therapeutically effective LNA oligonucleotides

#2851
20160032286
2016-02-04

Inhibitors of MYH7B and uses thereof

#2852
20160032285
2016-02-04

Compositions and methods for modulating Tau expression

#2853
20160024508
2016-01-28

Method for identifying biologically active oligonucleotides capable of modulating the immune system

#2854
20160024506
2016-01-28

Treatment of LCAT gene related diseases by inhibition of a natural antisense transcript to LCAT

#2855
20160024505
2016-01-28

Treatment of lipid transport and metabolism gene related diseases by inhibition of natural antisense transcript to a lipid transport and metabolism gene

#2856
20160024499
2016-01-28

Compositions and methods for inhibition of expression of protein C (PROC) genes

#2857
20160024496
2016-01-28

Methods for monitoring C9ORF72 expression

#2858
20160024495
2016-01-28

LNA antisense oligonucleotides for the modulation of Myc expression

#2859
20160024494
2016-01-28

COMPOSITIONS AND METHODS FOR ENHANCED SENSITIVITY AND SPECIFICITY OF NUCLEIC ACID SYNTHESIS

#2860
20160017337
2016-01-21

Compositions and Methods for Inhibiting Expression of Eg5 Gene

#2861
20160017335
2016-01-21

PCSK9 iRNA compositions and methods of use thereof

#2862
20160017330
2016-01-21

Serpinc1 iRNA compositions and methods of use thereof

#2863
20160017329
2016-01-21

Oligomeric compounds and compositions for use in modulation of small non-coding RNAs

#2864
20160017328
2016-01-21

DOUBLE STRAND COMPOSITIONS COMPRISING DIFFERENTIALLY MODIFIED STRANDS FOR USE IN GENE MODULATION

#2865
20160017322
2016-01-21

Reducing intron retention

#2866
20160010093
2016-01-14

Oligomers and oligomer conjugates

#2867
20160010092
2016-01-14

Treatment of tristetraproline (TTP) related diseases by inhibition of natural antisense transcript to TTP

#2868
20160010091
2016-01-14

Locked nucleic acid inhibitor of miR-145 and uses thereof

#2869
20160010090
2016-01-14

Bridged bicyclic nucleosides

#2870
20160010089
2016-01-14

Organic compositions to treat EPAS1-related diseases

#2871
20160002640
2016-01-07

Treatment of membrane bound transcription factor peptidase, site 1 (MBTPS1) related diseases by inhibition of natural antisense transcript to MBTPS1

#2872
20160002632
2016-01-07

Antisense oligonucleotides for inducing exon skipping and methods of use thereof

#2873
20160002631
2016-01-07

Antisense oligonucleotides for inducing exon skipping and methods of use thereof

#2874
20160002628
2016-01-07

METHODS AND COMPOSITIONS FOR MANAGING VASCULAR CONDITIONS

#2875
20160002627
2016-01-07

Compositions and methods for modulation of SMN2 splicing in a subject

#2876
20160002625
2016-01-07

Cancer treatment

#2877
20150376625
2015-12-31

Selective antisense compounds and uses thereof

#2878
20150376623
2015-12-31

Antisense oligonucleotides directed against connective tissue growth factor and uses thereof

#2879
20150376616
2015-12-31

Antisense oligonucleotides for inducing exon skipping and methods of use thereof

#2880
20150376615
2015-12-31

Antisense oligonucleotides for inducing exon skipping and methods of use thereof

#2881
20150376614
2015-12-31

Modulation of apolipoprotein C-III (ApoCIII) expression in lipoprotein lipase deficient (LPLD) populations

#2882
20150376612
2015-12-31

CCCTC-Binding Factor (CTCF) RNA Interactome

#2883
20150368644
2015-12-24

TREATMENT OF INTERFERON-RELATED DEVELOPMENTAL REGULATOR 1 (IFRD1) RELATED DISEASES BY INHIBITION OF NATURAL ANTISENSE TRANSCRIPT TO IFRD1

#2884
20150368642
2015-12-24

LNA OLIGONUCLEOTIDE CARBOHYDRATE CONJUGATES

#2885
20150361433
2015-12-17

Inhibitors of miRNAs 221 and 222 for anti-tumor activity in multiple myeloma

#2886
20150361427
2015-12-17

Compositions and methods for inhibiting gene expression of alpha-1 AntiTrypsin

#2887
20150353931
2015-12-10

Antisense oligonucleotides for inducing exon skipping and methods of use thereof

#2888
20150353930
2015-12-10

Methods of treating a metabolic syndrome by modulating heat shock protein (HSP) 90-beta

#2889
20150344879
2015-12-03

Compounds and methods for modulating gene expression

#2890
20150337318
2015-11-26

RNA TARGETED TO C-MET

#2891
20150337317
2015-11-26

dsRNA For Treating Viral Infection

#2892
20150337312
2015-11-26

Antisense oligonucleotides (ODN) against SMAD7 and uses thereof in medical field

#2893
20150337307
2015-11-26

Treatment of antiviral gene related diseases by inhibition of natural antisense transcript to an antiviral gene

#2894
20150337305
2015-11-26

Oligomeric compounds and compositions for use in modulation of small non-coding RNAs

#2895
20150337304
2015-11-26

Oligomeric compounds and compositions for use in modulation of small non-coding RNAs

#2896
20150337303
2015-11-26

Methods and compositions for modulating apolipoprotein (a) expression

#2897
20150329866
2015-11-19

Methods of treating ischemia-reperfusion injury with siRNAs

#2898
20150329864
2015-11-19

DESIGN OF OLIGONUCLEOTIDE ANALOGS AS THERAPEUTIC AGENTS

#2899
20150329859
2015-11-19

SELECTIVE REDUCTION OF ALLELIC VARIANTS

#2900
20150322436
2015-11-12

Oligomeric compounds and compositions for the use in modulation of micrornas

#2901
20150322429
2015-11-12

SNPs OF APOLIPOPROTEIN B AND MODULATION OF THEIR EXPRESSION

#2902
20150322428
2015-11-12

COMPOUNDS AND METHODS FOR IMPROVED CELLULAR UPTAKE OF ANTISENSE COMPOUNDS

#2903
20150315597
2015-11-05

Synthetic Nucleic Acids for Polymerization Reactions

#2904
20150315596
2015-11-05

Antisense modulation of PTP1B expression

#2905
20150315594
2015-11-05

Compositions and methods for modulating angiopoietin-like 3 expression

#2906
20150315591
2015-11-05

NICKED OR GAPPED NUCLEIC ACID MOLECULES AND USES THEREOF

#2907
20150315588
2015-11-05

Methods of delivering multiple targeting oligonucleotides to a cell using cleavable linkers

#2908
20150315587
2015-11-05

Multimeric oligonucleotides compounds having cleavable linkers

#2909
20150315586
2015-11-05

METHODS OF DELIVERING MULTIPLE TARGETING OLIGONUCLEOTIDES TO A CELL USING NON-NUCLEOTIDE BASED CLEAVABLE LINKERS

#2910
20150315585
2015-11-05

Multimeric oligonucleotide compounds having non-nucleotide based cleavable linkers

#2911
20150315582
2015-11-05

Deep intronic target for splicing correction on spinal muscular atrophy gene

#2912
20150315580
2015-11-05

COMPOUNDS AND METHODS FOR IMPROVING CELLULAR UPTAKE OF OLIGOMERIC COMPOUNDS

#2913
20150315579
2015-11-05

DOUBLE STRAND COMPOSITIONS COMPRISING DIFFERENTIALLY MODIFIED STRANDS FOR USE IN GENE MODULATION

#2914
20150315575
2015-11-05

Compositions and methods for selective delivery of oligonucleotide molecules to cell types

#2915
20150307877
2015-10-29

Compositions and their uses directed to huntingtin

#2916
20150299710
2015-10-22

Inhibitory oligonucleotide and use thereof

#2917
20150299704
2015-10-22

Methods for treatment of alport syndrome

#2918
20150299703
2015-10-22

In vivo gene silencing by chemically modified and stable siRNA

#2919
20150299701
2015-10-22

Treatment of reprogramming factor related diseases by inhibition of natural antisense transcript to a reprogramming factor

#2920
20150299699
2015-10-22

MICROMIRs

#2921
20150299695
2015-10-22

Multimeric oligonucleotides compounds

#2922
20150297629
2015-10-22

MODULATION OF RENIN-ANGIOTENSIN SYSTEM (RAS) RELATED DISEASES BY ANGIOTENSINOGEN

#2923
20150291960
2015-10-15

MODULATION OF CD40 EXPRESSION

#2924
20150291956
2015-10-15

RNA TARGETED TO BETA CATENIN

#2925
20150291955
2015-10-15

Antisense compounds targeting genes associated with fibronectin

#2926
20150290289
2015-10-15

Method of promoting wound healing

#2927
20150284726
2015-10-08

RNAi inhibition of alpha-ENaC expression

#2928
20150284725
2015-10-08

Methods of treating kennedy's disease

#2929
20150284708
2015-10-08

Oligonucleotide complex compositions and methods of use as gene alteration tools

#2930
20150275283
2015-10-01

Modified cytosine polynucleotide oligomers and methods

#2931
20150275218
2015-10-01

Organic compositions to treat beta-ENaC-related diseases

#2932
20150275217
2015-10-01

RIG-I ligands and methods for producing them

#2933
20150275216
2015-10-01

Methods and compositions for inhibition of immune responses and autoimmunity

#2934
20150275212
2015-10-01

Oligonucleotide conjugates

#2935
20150275205
2015-10-01

Methods for modulating Tau expression for reducing seizure and modifying a neurodegenerative syndrome

#2936
20150267204
2015-09-24

Treatment of Sirtuin (SIRT) related diseases by inhibition of natural antisense transcript to a Sirtuin (SIRT)

#2937
20150267200
2015-09-24

RNA interference mediated inhibition of gene expression using chemically modified short interfering nucleic acid (siNA)

#2938
20150267197
2015-09-24

Methods for modulating C9ORF72 expression

#2939
20150267195
2015-09-24

Oligomeric compounds comprising bicyclic nucleosides and uses thereof

#2940
20150259685
2015-09-17

Treatment of uncoupling protein 2 (UCP2) related diseases by inhibition of natural antisense transcript to UCP2

#2941
20150259680
2015-09-17

Nucleic acid functionalized nonoparticles for therapeutic applications

#2942
20150259679
2015-09-17

Compositions for modulating C9ORF72 expression

#2943
20150259675
2015-09-17

Short interfering ribonucleic acid (siRNA) for oral administration

#2944
20150252371
2015-09-10

Splice Switching Oligomers for TNF Superfamily Receptors and Their Use in Treatment of Disease

#2945
20150252367
2015-09-10

Modulation of transthyretin expression

#2946
20150252364
2015-09-10

Compositions and methods for modulating SMN gene family expression

#2947
20150247146
2015-09-03

Piggy back delivery of nucleic acids into organisms

#2948
20150247143
2015-09-03

Complement component C5 iRNA compositions and methods of use thereof

#2949
20150247142
2015-09-03

ANTISENSE COMPOUNDS HAVING ENHANCED ANTI-MICRORNA ACTIVITY

#2950
20150232850
2015-08-20

Treatment of insulin receptor substrate 2 (IRS2) related diseases by inhibition of natural antisense transcript to IRS2 and transcription factor E3 (TFE3)

#2951
20150232848
2015-08-20

Methods targeting miR-128 for regulating cholesterol/lipid metabolism

#2952
20150232842
2015-08-20

Treatment of fibrotic conditions

#2953
20150232841
2015-08-20

Methods for use in modulating miR-122A

#2954
20150232840
2015-08-20

Methods and compositions for treating neurological disease

#2955
20150232836
2015-08-20

COMPOSITIONS AND METHODS FOR MODULATING GENE EXPRESSION

#2956
20150225725
2015-08-13

Treatment of fibroblast growth factor 21 (FGF21) related diseases by inhibition of natural antisense transcript to FGF21

#2957
20150225724
2015-08-13

Treatment of adiponectin (ADIPOQ) related diseases by inhibition of natural antisense transcript to an adiponectin (ADIPOQ)

#2958
20150225717
2015-08-13

Selective reactivation of genes on the inactive X chromosome

#2959
20150218561
2015-08-06

Antisense oligonucleotides (ODN) against SMAD7 and uses thereof in medical field

#2960
20150218559
2015-08-06

MODULATION OF EXON RECOGNITION IN PRE-MRNA BY INTERFERING WITH THE SECONDARY RNA STRUCTURE

#2961
20150211011
2015-07-30

Antisense oligonucleotides (ODN) against SMAD7 and uses thereof in medical field

#2962
20150211010
2015-07-30

Restoration of the CFTR function by splicing modulation

#2963
20150211006
2015-07-30

Chiral control

#2964
20150203850
2015-07-23

Methods of treatment using TLR7 and/or TLR9 inhibitors

#2965
20150203849
2015-07-23

Oligonucleotide comprising an inosine for treating DMD

#2966
20150197753
2015-07-16

Method for Generating Aptamers with Improved Off-Rates

#2967
20150197750
2015-07-16

Treatment of ‘IQ motif containing gtpase activating protein’ (IQGAP) related diseases by inhibition of natural antisense transcript to IQGAP

#2968
20150191733
2015-07-09

Sense oligonucleotide capable of controlling the expression of INOS and composition comprising the same

#2969
20150191723
2015-07-09

Modulation of UBE3A-ATS expression

#2970
20150191722
2015-07-09

COMPOSITIONS AND METHODS FOR MODULATING APOA1 AND ABCA1 EXPRESSION

#2971
20150191523
2015-07-09

Toll-like receptors

#2972
20150184164
2015-07-02

ANTISENSE MODULATION OF FIBROBLAST GROWTH FACTOR RECEPTOR 4 EXPRESSION

#2973
20150184157
2015-07-02

MODULATION OF TRANSTHYRETIN EXPRESSION

#2974
20150184156
2015-07-02

MODULATION OF APOLIPOPROTEIN (a) EXPRESSION

#2975
20150184155
2015-07-02

METHODS FOR PREVENTING AND TREATING CHRONIC KIDNEY DISEASE (CKD)

#2976
20150176007
2015-06-25

Compositions and methods for modulating HBV expression

#2977
20150176005
2015-06-25

Modulation of enhancer RNA mediated gene expression

#2978
20150167008
2015-06-18

Antisense modulation of superoxide dismutase 1, soluble expression

#2979
20150167007
2015-06-18

TREATMENT OF SIALIDASE 4 (NEU4) RELATED DISEASES BY INHIBITION OF NATURAL ANTISENSE TRANSCRIPT TO NEU4

#2980
20150167006
2015-06-18

Oligomeric compounds and methods

#2981
20150166999
2015-06-18

Chiral nucleic acid adjuvant

#2982
20150166996
2015-06-18

Methods and means for efficient skipping of at least one of the exons 51-53, 55, 57 and 59 of the human duchenne muscular dystrophy gene

#2983
20150166995
2015-06-18

Antisense nucleic acids

#2984
20150166994
2015-06-18

Treatment of NANOG related diseases by inhibition of natural antisense transcript to NANOG

#2985
20150166465
2015-06-18

Lipid formulations

#2986
20150159163
2015-06-11

Modified nucleosides, analogs thereof and oligomeric compounds prepared therefrom

#2987
20150159162
2015-06-11

Treatment of tumor suppressor gene related diseases by inhibition of natural antisense transcript to the gene

#2988
20150159155
2015-06-11

Modulation of huntingtin expression

#2989
20150152426
2015-06-04

Treatment of PAR4 related diseases by inhibition of natural antisense transcript to PAR4

#2990
20150152425
2015-06-04

Treatment of Methionine sulfoxide reductase a (MSRA) related diseases by inhibition of natural antisense transcript to MSRA

#2991
20150152424
2015-06-04

Treatment of pyrroline-5-carboxylate reductase 1 (PYCR1) related diseases by inhibition of natural antisense transcript to PYCR1

#2992
20150152420
2015-06-04

Compounds and methods for altering RSV replication rate

#2993
20150152419
2015-06-04

Treatment of colony-stimulating factor 3 (CSF3) related diseases by inhibition of natural antisense transcript to CSF3

#2994
20150152417
2015-06-04

Treatment of filaggrin (FLG) related diseases by modulation of FLG expression and activity

#2995
20150152414
2015-06-04

Chemical modification of short small hairpin RNAs for inhibition of gene expression

#2996
20150152411
2015-06-04

METHODS AND COMPOSITIONS FOR MODULATING APOLIPOPROTEIN (A) EXPRESSION

#2997
20150152410
2015-06-04

COMPOSITIONS AND METHODS FOR MODULATING MECP2 EXPRESSION

#2998
20150148404
2015-05-28

RNA modulating oligonucleotides with improved characteristics for the treatment of neuromuscular disorders

#2999
20150141493
2015-05-21

Antisense modulation of GCCR expression

#3000
20150141489
2015-05-21

Methods of treating and diagnosing diseases using agents that regulate the alternative splicing pathway