ClassID:

109162

C12N2310/315 - page 13 - CPC Classification

Classification description:

Structure or type of the nucleic acid; Chemical structure of the backbone Phosphorothioates

Recent Application in this class:
#3601
20100168206
2010-07-01

GNAQ targeted dsRNA compositions and methods for inhibiting expression

#3602
20100168205
2010-07-01

Methods and Compositions for Prevention or Treatment of RSV Infection Using Modified Duplex RNA Molecules

#3603
20100166805
2010-07-01

Modulation of immunostimulatory properties by small oligonucleotide-based compounds

#3604
20100166780
2010-07-01

CpG oligonucleotide analogs containing hydrophobic T analogs with enhanced immunostimulatory activity

#3605
20100166736
2010-07-01

Immunostimulatory oligonucleotide multimers

#3606
20100160208
2010-06-24

Pharmaceutical composition

#3607
20100152280
2010-06-17

MODULATION OF SID-1 EXPRESSION

#3608
20100152278
2010-06-17

RNA Interference Mediated Inhibition of Cyclic Nucleotide Type 4 Phosphodiesterase (PDE4B) Gene Expression Using Short Interfering Nucleic Acid (siNA)

#3609
20100151458
2010-06-17

OLIGORIBONUCLEOTIDES AND RIBONUCLEASES FOR CLEAVING RNA

#3610
20100144846
2010-06-10

Oligoribonucleotides and uses thereof

#3611
20100144837
2010-06-10

DIAGNOSIS AND TREATMENT OF MALIGNANT NEOPLASMS

#3612
20100144834
2010-06-10

Methods for treating hypercholesterolemia

#3613
20100137414
2010-06-03

Modulation of factor 11 expression

#3614
20100136695
2010-06-03

DOUBLE-STRANDED OLIGONUCLEOTIDES

#3615
20100136581
2010-06-03

DIAGNOSIS AND TREATMENT OF MALIGNANT NEOPLASMS

#3616
20100136547
2010-06-03

Pure miRNA Sample Preparation Method

#3617
20100130595
2010-05-27

Antisense oligonucleotides directed against connective tissue growth factor and uses thereof

#3618
20100130593
2010-05-27

METHODS AND IMMUNE MODULATOR NUCLEIC ACID COMPOSITIONS FOR PREVENTING AND TREATING DISEASE

#3619
20100130589
2010-05-27

MODULATION OF eIF4E EXPRESSION

#3620
20100125101
2010-05-20

Methods of using immunostimulatory nucleic acid molecules to treat allergic conditions

#3621
20100125099
2010-05-20

Therapeutic intervention in a genetic disease in an individual by modifying expression of an aberrantly or abnormally expressed gene

#3622
20100120893
2010-05-13

Compositions and methods for inhibiting expression of transthyretin

#3623
20100119480
2010-05-13

Methods for treating multiple sclerosis using antisense oligonucleotides

#3624
20100113573
2010-05-06

Modulation of HIF1-beta expression

#3625
20100113562
2010-05-06

Therapeutic targets and molecules

#3626
20100099750
2010-04-22

RNA interference mediated inhibition of muscarinic colinergic receptor gene expression using short interfering nucleic acid (siNA)

#3627
20100099743
2010-04-22

RNA interference mediated inhibition of checkpoint kinase-1 (CHK-1) gene expression using short interfering nucleic acid (siNA)

#3628
20100099739
2010-04-22

Compositions and methods for gene silencing

#3629
20100093987
2010-04-15

Inhibitor Nucleic Acids

#3630
20100093839
2010-04-15

Oligomeric compounds for the modulation of HIF-1alpha expression

#3631
20100093836
2010-04-15

COMPOUNDS AND METHODS FOR MODULATING PROTEIN EXPRESSION

#3632
20100093833
2010-04-15

Methods for inducing differentiation of undifferentiated mammalian cells into osteoblasts

#3633
20100093831
2010-04-15

NUCLEIC ACID COMPOUNDS FOR INHIBITING ANGIOGENESIS AND TUMOR GROWTH

#3634
20100093085
2010-04-15

Tripartite oligonucleotide complexes and methods for gene silencing by RNA interference

#3635
20100093002
2010-04-15

Diagnosis and treatment of malignant neoplasms

#3636
20100092486
2010-04-15

MODULATION OF MYELOID DIFFERENTATION PRIMARY RESPONSE GENE 88 (MYD88) EXPRESSION BY ANTISENSE OLIGONUCLEOTIDES

#3637
20100087511
2010-04-08

Spinal muscular atrophy (SMA) treatment via targeting of splice site inhibitory sequences

#3638
20100087508
2010-04-08

Compositions and Methods for Inhibiting Expression of Eg5 and VEGF Genes

#3639
20100081705
2010-04-01

METHODS FOR SLOWING FAMILIAL ALS DISEASE PROGRESSION

#3640
20100069472
2010-03-18

COMPOSITIONS AND THEIR USES DIRECTED TO HUNTINGTIN

#3641
20100056606
2010-03-04

Combination therapy using budesonide and antisense oligonucleotide targeted to IL4-receptor alpha

#3642
20100048673
2010-02-25

Oligonucleotides affecting expression of phosphodiesterases

#3643
20100047188
2010-02-25

MODULATION OF TOLL-LIKE RECEPTOR 8 EXPRESSION BY ANTISENSE OLIGONUCLEOTIDES

#3644
20100041047
2010-02-18

EFFICIENT REDUCTION OF TARGET RNA'S BY SINGLE- AND DOUBLE-STRANDED OLIGOMERIC COMPOUNDS

#3645
20100040576
2010-02-18

Modified Oligonucleotides For The Treatment Of Hepatitis C Infection

#3646
20100035976
2010-02-11

Method of treating a cancer by administering A 2′,5′-oligoadenylate analog

#3647
20100035964
2010-02-11

Antisense modulation of connective tissue growth factor expression

#3648
20100035310
2010-02-11

Production of functional proteins: balance of shear stress and gravity

#3649
20100034835
2010-02-11

USE OF INHIBITORS OF LEUKOTRIENE B4 RECEPTOR BLT2 FOR TREATING ASTHMA

#3650
20100022619
2010-01-28

Compositions and their uses directed to PTPR alpha

#3651
20100021914
2010-01-28

OLIGONUCLEOTIDES FOR MODULATING TARGET RNA ACTIVITY

#3652
20100021467
2010-01-28

METHOD OF DETECTING A CANCER CELL BY ABERRANT EXPRESSION OF A HUMAN K+ ION CHANNEL

#3653
20100016405
2010-01-21

Compositions and methods for inhibiting expression of the MYC gene

#3654
20100015707
2010-01-21

Short interfering ribonucleic acid (siRNA) with improved pharmacological properties

#3655
20100010066
2010-01-14

Optimized Methods For Delivery Of DSRNA Targeting The PCSK9 Gene

#3656
20090326047
2009-12-31

Antiproliferative activity of G-rich oligonucleotides and method of using same to bind to nucleolin

#3657
20090326042
2009-12-31

COMPOUNDS AND METHODS FOR MODULATING EXPRESSION OF CRP

#3658
20090326041
2009-12-31

COMPOUNDS AND METHODS FOR MODULATING EXPRESSION OF SGLT2

#3659
20090326040
2009-12-31

ANTISENSE MODULATION OF APOLIPOPROTEIN B EXPRESSION

#3660
20090318532
2009-12-24

Compounds and methods for modulating expression of PTP1B

#3661
20090317907
2009-12-24

Oligomeric compounds and compositions for use in modulation of small non-coding RNAs

#3662
20090317480
2009-12-24

Chimeric immunomodulatory compounds and methods of using the same-II

#3663
20090317403
2009-12-24

Use of CSF-1 Inhibitors

#3664
20090312398
2009-12-17

Compositions and their uses directed to IL-4R alpha

#3665
20090312397
2009-12-17

RNAi modulation of ApoB and uses thereof

#3666
20090311716
2009-12-17

METHODS TO TREAT OR PREVENT HORMONE-RESISTANT PROSTATE CANCER USING siRNA SPECIFIC FOR PROTOCADHERIN-PC, OR OTHER INHIBITORS OF PROTOCADHERIN-PC EXPRESSION OR ACTIVITY

#3667
20090306357
2009-12-10

Compounds and methods for modulating expression of GCCR

#3668
20090306180
2009-12-10

Compounds and methods for modulating expression ApoB

#3669
20090306179
2009-12-10

Compounds and methods for modulating expression of GCGR

#3670
20090306178
2009-12-10

CONJUGATED DOUBLE STRAND COMPOSITIONS FOR USE IN GENE MODULATION

#3671
20090306005
2009-12-10

Compounds and methods for modulating expression of PCSK9

#3672
20090298910
2009-12-03

Regulation of epigenetic control of gene expression

#3673
20090298174
2009-12-03

Oligomeric compounds and compositions for use in modulation of small non-coding RNAs

#3674
20090292009
2009-11-26

MODULATION OF STAT 6 EXPRESSION

#3675
20090292006
2009-11-26

COMPOUNDS AND METHODS FOR MODULATING EXPRESSION OF DGAT2

#3676
20090291907
2009-11-26

Oligomeric compounds and compositions for use in modulation of small non-coding RNAs

#3677
20090291906
2009-11-26

Oligomeric compounds and compositions for use in modulation of small non-coding RNAs

#3678
20090286969
2009-11-19

Oligomeric Compounds And Compositions For Use In Modulation Of Small Non-Coding RNAs

#3679
20090286859
2009-11-19

Potent LNA oligonucleotides for the inhibition of HIF-1a expression

#3680
20090286851
2009-11-19

Compositions and methods for delivering RNAI using lipoproteins

#3681
20090286849
2009-11-19

Modulation of insulin like growth factor I receptor expression

#3682
20090285817
2009-11-19

Mixture comprising an inhibitor or suppressor of a gene and a molecule binding to an expression product of that gene

#3683
20090281169
2009-11-12

Compositions and Their Uses Directed to IL-4R Alpha

#3684
20090281165
2009-11-12

Antisense oligonucleotide against human acetylcholinesterase (AChE) and uses thereof

#3685
20090281164
2009-11-12

RNA interference mediated inhibition of respiratory syncytial virus (RSV) expression using short interfering nucleic acid (siNA)

#3686
20090275638
2009-11-05

Compositions and methods for inhibiting expression of XBP-1 gene

#3687
20090275631
2009-11-05

THERAPEUTIC ANTISENSE OLIGONUCLEOTIDE COMPOSITION FOR THE TREATMENT OF INFLAMMATORY BOWEL DISEASE

#3688
20090275133
2009-11-05

Antisense modulation of C-reactive protein expression

#3689
20090275100
2009-11-05

Compositions and methods for temperature-dependent nucleic acid synthesis

#3690
20090270491
2009-10-29

MODULATION OF TUDOR-SN EXPRESSION

#3691
20090270486
2009-10-29

HUMAN RNASE III AND COMPOSITIONS AND USES THEREOF

#3692
20090269755
2009-10-29

Means and method for inducing exon-skipping

#3693
20090269739
2009-10-29

Kit for detection of telomerase reverse transcriptase nucleic acids

#3694
20090264636
2009-10-22

Conjugates and compositions for cellular delivery

#3695
20090264511
2009-10-22

Compositions and methods for inhibiting expression of factor VII gene

#3696
20090264506
2009-10-22

DELIVERY OF POLYNUCLEOTIDE AGENTS TO THE CENTRAL NERVOUS SYSTEM

#3697
20090263405
2009-10-22

CpG oligonucleotide prodrugs, compositions thereof and associated therapeutic methods

#3698
20090258934
2009-10-15

Compositions and methods for inhibiting expression of Nav1.8 gene

#3699
20090253772
2009-10-08

RNA interference mediated inhibition of CXCR4 gene expression using short interfering nucleic acid (siNA)

#3700
20090247613
2009-10-01

RNA INTERFERENCE MEDIATED INHIBITION OF B-CELL CLL/LYMPHOMA-2 (BCL2) GENE EXPRESSION USING SHORT INTERFERING NUCLEIC ACID (siNA)

#3701
20090247612
2009-10-01

PREVENTION OF VIRAL INFECTIVITY

#3702
20090247607
2009-10-01

dsRNA compositions and methods for treating HPV infection

#3703
20090247606
2009-10-01

RNA Interference Mediated Inhibition of Adenosine A1 Receptor (ADORA1) Gene Expression Using Short Interfering Nucleic Acid (siNA)

#3704
20090246221
2009-10-01

Immunomodulatory agents and methods of use

#3705
20090239933
2009-09-24

HEPATITIS C ANTIVIRALS

#3706
20090239931
2009-09-24

RNA INTERFERENCE MEDIATED INHIBITION OF PROTEIN TYROSINE PHOSPHATASE-1B (PTP-1B) GENE EXPRESSION USING SHORT INTERFERING NUCLEIC ACID (siNA)

#3707
20090233989
2009-09-17

Oligonucleotides stimulatory of the mesenchymal stem cell proliferation and uses thereof

#3708
20090228998
2009-09-10

Induction of exon skipping in eukaryotic cells

#3709
20090221686
2009-09-03

Modulation of the Transcription of Pro-Inflammatory Gene Products

#3710
20090221685
2009-09-03

Oligomeric compounds and compositions for the use in modulation of microRNAs

#3711
20090221678
2009-09-03

Compositions and methods for treatment of prostate and other cancers

#3712
20090221671
2009-09-03

MODULATION OF LMW-PTPASE EXPRESSION

#3713
20090214578
2009-08-27

Immunostimulatory Single-Stranded Ribonucleic Acid with Phosphodiester Backbone

#3714
20090209748
2009-08-20

Oligonucleotides with alternating segments of locked and non-locked nucleotides

#3715
20090209629
2009-08-20

Nucleic acid functionalized nanoparticles for therapeutic applications

#3716
20090209620
2009-08-20

Direct Reversal Of The Suppressive Function Of CD4+Regulatory T Cells Via Toll-Like Receptor 8 Signaling

#3717
20090209478
2009-08-20

COMPOSITIONS AND METHODS FOR INHIBITING EXPRESSION OF THE HAMP GENE

#3718
20090208564
2009-08-20

Compositions of asymmetric interfering RNA and uses thereof

#3719
20090208468
2009-08-20

Suppressors of CpG oligonucleotides and methods of use

#3720
20090203896
2009-08-13

MODULATION OF SURVIVIN EXPRESSION

#3721
20090203893
2009-08-13

ANTISENSE COMPOUNDS HAVING ENHANCED ANTI-MICRORNA ACTIVITY

#3722
20090203890
2009-08-13

HEPATITIS C ANTIVIRALS

#3723
20090203766
2009-08-13

vWF aptamer formulations and methods for use

#3724
20090203765
2009-08-13

Modulation of eIF4E-BP2 expression

#3725
20090203137
2009-08-13

Compounds for the modulation of beta-catenin expression

#3726
20090203135
2009-08-13

Glycoconjugates of RNA interference agents

#3727
20090202575
2009-08-13

IMMUNOSTIMULATORY NUCLEIC ACID MOLECULES

#3728
20090202567
2009-08-13

OLIGONUCLEOTIDES OR THEIR FUNCTIONAL HOMOLOGUES, A COMPOSITION COMPRISING THE SAME AND A METHOD OF TREATING B CELL NEOPLASM

#3729
20090202493
2009-08-13

MIR-150 FOR THE TREATMENT OF BLOOD DISORDERS

#3730
20090198047
2009-08-06

2'-Modified Oligonucleotides

#3731
20090192113
2009-07-30

Interfering RNA duplex having blunt-ends and 3′-modifications

#3732
20090192110
2009-07-30

RNA antagonist compounds for the modulation of PIK3CA expression

#3733
20090192106
2009-07-30

Modulation of eIF4E expression

#3734
20090192105
2009-07-30

RNA INTERFERENCE MEDIATED INHIBITION OF INTERCELLULAR ADHESION MOLECULE (ICAM) GENE EXPRESSION USING SHORT INTERFERING NUCELIC ACID (siNA)

#3735
20090192104
2009-07-30

RNA interference mediated inhibition of hypoxia inducible factor 1 (HIF1) gene expression using short interfering nucleic acid (siNA)

#3736
20090191185
2009-07-30

Reducing Cancer Cell Invasion Using an Inhibitor of Toll Like Receptor Signaling

#3737
20090191170
2009-07-30

Nucleic acid compositions and methods of introducing nucleic acids into cells

#3738
20090191133
2009-07-30

MODULATION OF STAT 6 EXPRESSION FOR THE TREATMENT OF AIRWAY HYPERRESPONSIVENESS

#3739
20090188009
2009-07-23

Constitutively active fragments of eukaryotic heat shock RNA

#3740
20090181916
2009-07-16

LNA antagonists targeting the androgen receptor

#3741
20090181914
2009-07-16

LNA oligonucleotides and the treatment of cancer

#3742
20090176729
2009-07-09

METHOD OF TREATING NEURODEGENERATIVE DISEASE

#3743
20090176710
2009-07-09

Complex for transferring an anionic substance into a cell

#3744
20090170799
2009-07-02

Modulation of C-reactive protein expression

#3745
20090170197
2009-07-02

Nucleic Acid-Mediated Treatment of Diseases or Conditions Related to Levels of Vascular Endothelial Growth Factor Receptor (VEGF-R)

#3746
20090169472
2009-07-02

METHODS AND COMPOSITIONS FOR TREATING IMMUNE DISORDERS

#3747
20090162365
2009-06-25

Novel siRNAS and methods of use thereof

#3748
20090162349
2009-06-25

METHOD FOR PREVENTION OR TREATMENT OF DISEASES OR DISORDERS RELATED TO EXCESSIVE FORMATION OF VASCULAR TISSUE OR BLOOD VESSELS

#3749
20090162279
2009-06-25

Oligonucleotide or its functional homologue, a composition comprising the same and a method of treating B cell neoplasm

#3750
20090156541
2009-06-18

DBAIT and uses thereof

#3751
20090156539
2009-06-18

Antisense oligonucleotides (ODN) against Smad7 and uses thereof in medical field

#3752
20090156538
2009-06-18

MODULATION OF ENDOTHELIAL LIPASE EXPRESSION

#3753
20090156529
2009-06-18

RNAi inhibition of alpha-ENaC expression

#3754
20090156528
2009-06-18

RNA interference mediated inhibition of hepatitis C virus (HCV) gene expression using short interfering nucleic acid (siNA)

#3755
20090156527
2009-06-18

Antiviral oligonucleotides targeting viral families

#3756
20090156524
2009-06-18

Novel siRNAS and methods of use thereof

#3757
20090155251
2009-06-18

Polypeptide compounds for inhibiting angiogenesis and tumor growth

#3758
20090149643
2009-06-11

Aptamers to von Willebrand factor and their use as thrombotic disease therapeutics

#3759
20090149408
2009-06-11

RNA interference mediated inhibition of telomerase gene expression using short interfering nucleic acid (siNA)

#3760
20090149407
2009-06-11

RNA interference mediated treatment of Alzheimer's disease using short interfering nucleic acid (siNA)

#3761
20090149339
2009-06-11

Methods of Identifying Modulators of Interaction Between PDZ Domain Proteins and PL Proteins

#3762
20090143326
2009-06-04

MicroRNAs

#3763
20090143323
2009-06-04

Compositions and methods for inhibiting expression of a gene from the Ebola

#3764
20090143320
2009-06-04

Kinase suppressor of Ras inactivation for therapy of Ras mediated tumorigenesis

#3765
20090143319
2009-06-04

Transcription factor decoy

#3766
20090142310
2009-06-04

Method of treating inflammatory arthropathies with suppressors of CpG oligonucleotides

#3767
20090137519
2009-05-28

Semi-soft c-class immunostimulatory oligonucleotides

#3768
20090137513
2009-05-28

RNA Interference Mediated Inhibition of Acetyl-CoA-Carboxylase Gene Expression Using Short Interfering Nucleic Acid (siNA)

#3769
20090137512
2009-05-28

RNA interference mediated inhibition of cyclin D1 gene expression using short interfering nucleic acid (siNA)

#3770
20090137511
2009-05-28

RNA interference mediated inhibition of placental growth factor gene expression using short interfering nucleic acid (SINA)

#3771
20090137509
2009-05-28

RNA INTERFERENCE MEDIATED INHIBITION OF PROLIFERATION CELL NUCLEAR ANTIGEN (PCNA) GENE EXPRESSION USING SHORT INTERFERING NUCLEIC ACID (siNA)

#3772
20090137508
2009-05-28

RNA interference mediated inhibition of polycomb group protein EZH2 gene expression using short interfering nucleic acid (siNA)

#3773
20090136508
2009-05-28

METHOD OF DIAGNOSING COLON AND GASTRIC CANCERS

#3774
20090131360
2009-05-21

Tripartite RNAi constructs

#3775
20090124009
2009-05-14

Antisense modulation of PTP1B expression

#3776
20090118213
2009-05-07

RNA ANTAGONIST COMPOUNDS FOR THE INHIBITION OF APO-B100 EXPRESSION

#3777
20090118205
2009-05-07

Antisense Oligonucleotides Directed to Ribonucleotide Reductase R2 and uses Thereof in the Treatment of Cancer

#3778
20090111767
2009-04-30

MODULATION OF INSULIN LIKE GROWTH FACTOR I RECEPTOR EXPRESSION

#3779
20090105177
2009-04-23

Modulation of diacylglycerol acyltransferase 1 expression

#3780
20090105174
2009-04-23

NUCLEIC ACIDS HYBRIDIZABLE TO MICRO RNA AND PRECURSORS THEREOF

#3781
20090099123
2009-04-16

Antisense microRNA and uses therefor

#3782
20090099120
2009-04-16

RNA interference mediated inhibition of muscarinic colinergic receptor gene expression using short interfering nucleic acid (siNA)

#3783
20090099119
2009-04-16

RNA INTERFERENCE MEDIATED INHIBITION OF RAS GENE EXPRESSION USING SHORT INTERFERING NUCLEIC ACID (siNA)

#3784
20090099118
2009-04-16

RNA interference mediated inhibition of Stearoyl-CoA desaturase (SCD) gene expression using short interfering nucelic acid (siNA)

#3785
20090099115
2009-04-16

RNA interference mediated inhibition of MYC and/or MYB gene expression using short interfering nucleic acid (siNA)

#3786
20090099110
2009-04-16

Antiviral oligonucleotides

#3787
20090093438
2009-04-09

RNA interference mediated inhibition of XIAP gene expression using short interfering nucleic acid (siNA)

#3788
20090093437
2009-04-09

RNA interference mediated inhibition of checkpoint kinase-1 (CHK-1) gene expression using short interfering nucleic acid (siNA)

#3789
20090093426
2009-04-09

RNAi modulation of SCAP and therapeutics uses thereof

#3790
20090093425
2009-04-09

TRANSDUCIBLE DELIVERY OF NUCLEIC ACIDS BY REVERSIBLE PHOSPHOTRIESTER CHARGE NEUTRALIZATION PROTECTING GROUPS

#3791
20090088721
2009-04-02

Enhanced retinal delivery of a nucleic acid through iontophoresis

#3792
20090087446
2009-04-02

Combination motif immune stimulatory oligonucleotides with improved activity

#3793
20090087424
2009-04-02

Modulating Retinal Pigmented Epithelium Permeaion By Inhibiting Or Activating VEGFR-1

#3794
20090082302
2009-03-26

Modulation of eIF4E-BP2 expression

#3795
20090082300
2009-03-26

Modulation of transthyretin expression

#3796
20090082295
2009-03-26

COMBINATIONS AND METHODS OF USING AN IMMUNOMODULATORY OLIGODEOXYNUCLEOTIDE

#3797
20090082288
2009-03-26

Methods and compositions for the treatment of uveitis

#3798
20090076246
2009-03-19

Modulation of exon recognition in pre-mRNA by interfering with the secondary RNA structure

#3799
20090075924
2009-03-19

Modulation of apolipoprotein (a) expression

#3800
20090075342
2009-03-19

Metabolic profile directed aptamer medicinal chemistry

#3801
20090068208
2009-03-12

Long term disease modification using immunostimulatory oligonucleotides

#3802
20090062225
2009-03-05

Compositions and methods for inhibiting expression of a gene from the JC virus

#3803
20090053808
2009-02-26

Compositions and methods for inhibiting expression of anti-apoptotic genes

#3804
20090053232
2009-02-26

MODULATION OF SYNAPTOGENESIS

#3805
20090048435
2009-02-19

Oligonucleotide modulation of cell adhesion

#3806
20090042827
2009-02-12

Antiviral oligonucleotides targeting HBV

#3807
20090029931
2009-01-29

Topical administrations of antisense compounds to VLA-4 for the treatment of respiratory conditions

#3808
20090023676
2009-01-22

RNA Interference Mediated Inhibition of MAP Kinase Gene Expression or Expression of Genes Involved in MAP Kinase Pathway Using Short Interfering Nucleic Acid (SiNA)

#3809
20090023675
2009-01-22

RNA interference mediated inhibition of gene expression using chemically modified short interfering nucleic acid (siNA)

#3810
20090023216
2009-01-22

Double-Stranded Oligonucleotides

#3811
20090018093
2009-01-15

Nucleic Acid Ligands Specific to Immunoglobuline E and Their Use as Atopic Disease Therapeutics

#3812
20090017103
2009-01-15

Antisense oligonucleotides for prevention of metastasis formation of cancer cells

#3813
20090010907
2009-01-08

Dnazymes for Inhibition of Japanese Encephalitis Virus Replication

#3814
20090005335
2009-01-01

COMPOUNDS FOR THE MODULATION OF BETA-CATENIN EXPRESSION

#3815
20090004667
2009-01-01

Method for generating aptamers with improved off-rates

#3816
20080318894
2008-12-25

RNA antagonist compounds for the modulation of HER3

#3817
20080318891
2008-12-25

Antisense oligonucleotides against thymidylate synthase

#3818
20080318885
2008-12-25

Method for modulating responsiveness to steroids

#3819
20080317759
2008-12-25

Therapeutic uses of factors which inhibit or neutralize MIF activity

#3820
20080311126
2008-12-18

Antisense Oligonucleotides Directed to Ribonucleotide Reducatase R2 and Uses Thereof in Combination Therapies for the Treatment of Cancer

#3821
20080311052
2008-12-18

Isis Pharmaceuticals, Inc.

#3822
20080300212
2008-12-04

Treatment and prevention of hyperproliferative conditions in humans and antisense oligonucleotide inhibition of human replication-initiation proteins

#3823
20080293662
2008-11-27

RNAi MODULATION OF THE BCR-ABL FUSION GENE AND USES THEREOF

#3824
20080293657
2008-11-27

MODULATION OF THE EXPRESSION OF STAT-1-DEPENDENT GENES

#3825
20080293655
2008-11-27

Tandem siRNAS

#3826
20080292648
2008-11-27

Synthetic agonists of TLR9

#3827
20080292619
2008-11-27

Pharmaceutical Composition Containing Meltrin Antagonist

#3828
20080287380
2008-11-20

Antisense oligonucleotides against cPLA, compositions and uses thereof

#3829
20080287379
2008-11-20

Oligonucleotide complex compositions and methods of use as gene alteration tools

#3830
20080280845
2008-11-13

Compositions and their uses directed to PTPRU

#3831
20080279871
2008-11-13

Method for eliciting an immune response to human telomerase reverse transcriptase

#3832
20080274996
2008-11-06

RNAi probes targeting cancer-related proteins

#3833
20080274995
2008-11-06

Suppression of nuclear factor-κB dependent processes using oligonucleotides

#3834
20080268051
2008-10-30

High viscosity macromolecular compositions for treating ocular conditions

#3835
20080260742
2008-10-23

Preventives/Remedies for Cancer

#3836
20080255066
2008-10-16

ANTISENSE OLIGONUCLEOTIDE STRATEGIES FOR THE ENHANCEMENT OF CANCER THERAPIES

#3837
20080255030
2008-10-16

Compositions and methods for the modulation of JNK proteins

#3838
20080249294
2008-10-09

RNA Interference Mediated Inhibition of Gene Expression Using Short Interfering Nucleic Acid (siNA)

#3839
20080249039
2008-10-09

Modified Short Interfering Rna (Modified Sirna)

#3840
20080242851
2008-10-02

Modified polynucleotides for reducing off-target effects in RNA interference

#3841
20080242629
2008-10-02

Antisense modulation of apolipoprotein B expression

#3842
20080242602
2008-10-02

Methods and compositions for the inhibition of HIV-1 replication

#3843
20080241825
2008-10-02

Materials and methods for treatment of cancer

#3844
20080234217
2008-09-25

Inhibitor Nucleic Acids

#3845
20080221055
2008-09-11

Compositions and methods for inhibiting expression of Huntingtin gene

#3846
20080214517
2008-09-04

Modulation of the Expression of Estrogen Receptors for the Prevention or Treatment of Heart Disease

#3847
20080214489
2008-09-04

Aptamer-mediated intracellular delivery of oligonucleotides

#3848
20080214483
2008-09-04

Antisense-oligonucleotides for the treatment of immuno-suppressive effects of transforming growth factor-β (TGF-β)

#3849
20080213813
2008-09-04

Histone deacetylase inhibitor and use thereof

#3850
20080209581
2008-08-28

Induction of exon skipping in eukaryotic cells

#3851
20080207552
2008-08-28

Decoy compositions for treating and preventing brain diseases and disorders

#3852
20080207550
2008-08-28

Immunomodulatory polynucleotides and methods of using the same

#3853
20080207541
2008-08-28

Compositions and methods for optimizing cleavage of RNA by RNase H

#3854
20080206253
2008-08-28

Method For Preventing or Treating Pain in a Mammal

#3855
20080200416
2008-08-21

Modulation of T cell signaling threshold and T cell sensitivity to antigens

#3856
20080200409
2008-08-21

Antisense oligonucleotides for inducing exon skipping and methods of use thereof

#3857
20080194503
2008-08-14

Antisense modulation of p38 mitogen activated protein kinase expression

#3858
20080193437
2008-08-14

IMMUNOSTIMULATORY OLIGONUCLEOTIDE MULTIMERS

#3859
20080188432
2008-08-07

Oligomeric compounds for the modulation ras expression

#3860
20080188430
2008-08-07

RNA interference mediated inhibition of hypoxia inducible factor 1 (HIF1) gene expression using short interfering nucleic acid (siNA)

#3861
20080182810
2008-07-31

ANTISENSE MODULATION OF ACYL COA CHOLESTEROL ACYLTRANSFERASE-2 EXPRESSION

#3862
20080182808
2008-07-31

OLIGORIBONUCLEOTIDES FOR THE TREATMENT OF DEGENERATIVE SKIN CONDITIONS BY RNA INTERFERENCE

#3863
20080181909
2008-07-31

Chimeric immunomodulatory compounds and methods of using the same

#3864
20080171712
2008-07-17

Stabilized immune modulatory RNA (SIMRA) compounds for TLR7 and TLR8

#3865
20080171388
2008-07-17

COMPOSITIONS AND METHODS FOR ENHANCED SENSITIVITY AND SPECIFICITY OF NUCLEIC ACID SYNTHESIS

#3866
20080167265
2008-07-10

Modulation of FR-alpha expression

#3867
20080153768
2008-06-26

Treatment of neurological disorders by dsRNA administration

#3868
20080153767
2008-06-26

Modulation of forkhead box O1A expression

#3869
20080153766
2008-06-26

Antisense modulation of stearoyl-CoA desaturase expression

#3870
20080153765
2008-06-26

Methods of use of bcl-6-derived nucleotides to induce apoptosis

#3871
20080146788
2008-06-19

Positionally modified siRNA constructs

#3872
20080119427
2008-05-22

Double Strand Compositions Comprising Differentially Modified Strands for Use in Gene Modulation

#3873
20080119425
2008-05-22

Clusterin antisense therapy for treatment of cancer

#3874
20080113930
2008-05-15

Compositions and methods for inhibiting expression of the PCSK9 gene

#3875
20080108584
2008-05-08

Compositions and methods for inhibiting expression of IKK-B gene

#3876
20080103106
2008-05-01

COMPOSITIONS AND THEIR USES DIRECTED TO IL-4R ALPHA

#3877
20080096840
2008-04-24

Kinase suppressor of Ras inactivation for therapy of Ras mediated tumorigenesis

#3878
20080096835
2008-04-24

Inhibitory oligonucleotides targeted to BCL-2

#3879
20080085869
2008-04-10

Duplex oligonucleotide complexes and methods for gene silencing by RNA interference

#3880
20080081795
2008-04-03

Suppression of nuclear factor-κB dependent processes using oligonucleotides

#3881
20080069825
2008-03-20

Multiple CpG oligodeoxynucleotides and their use to induce an immune response

#3882
20080064651
2008-03-13

TRPM-2 antisense therapy

#3883
20080051363
2008-02-28

G-rich polynucleotides as a novel therapeutic for the treatment of huntington's disease

#3884
20080051359
2008-02-28

ANTISENSE OLIGONUCLEOTIDE MODULATION OF STAT3 EXPRESSION

#3885
20080050363
2008-02-28

Opioid growth factor receptors

#3886
20080039418
2008-02-14

Compositions and their uses directed to huntingtin

#3887
20080039415
2008-02-14

RETROGRADE TRANSPORT OF SIRNA AND THERAPEUTIC USES TO TREAT NEUROLOGIC DISORDERS

#3888
20080039369
2008-02-14

Microsphere-based composition for preventing and/or reversing new-onset autoimmune diabetes

#3889
20080033156
2008-02-07

Polycationic compositions for cellular delivery of polynucleotides

#3890
20080032945
2008-02-07

2'-MODIFIED OLIGONUCLEOTIDES

#3891
20080032942
2008-02-07

RNA interference mediated treatment of Alzheimer's disease using short interfering nucleic acid (siNA)

#3892
20080031936
2008-02-07

Immunostimulatory nucleic acid molecules

#3893
20080026011
2008-01-31

Immunostimulatory nucleic acid molecules

#3894
20080020991
2008-01-24

Methods of treating, reducing, or preventing autoimmune conditions

#3895
20080020406
2008-01-24

Antibodies to a human Kchannel and therapeutic applications thereof

#3896
20080015162
2008-01-17

Short antisense compounds with gapmer configuration

#3897
20080009459
2008-01-10

Methods of reducing papillomavirus infection using immunomodulatory polynucleotide sequences

#3898
20080009456
2008-01-10

Antisense modulation of kinesin-like 1 expression

#3899
20080009455
2008-01-10

Immunostimulatory oligonucleotides

#3900
20070299028
2007-12-27

BACKBONE MODIFICATIONS TO MODULATE OLIGONUCLEOTIDE TARGETING IN VIVO