108915 ⎘
Enzymes; Proenzymes; Compositions thereof ; Processes for preparing, activating, inhibiting, separating or purifying enzymes; Transferases (2.) transferring phosphorus containing groups, e.g. kinases (2.7)
Soluble fibroblast growth factor receptor 3 (FGR3) polypeptide for use in the prevention or treatment of skeletal growth retardation disorders
#302Soluble fibroblast growth factor receptor 3 (FGR3) polypeptide for use in the prevention or treatment of skeletal growth retardation disorders
#303Methods, compositions, and uses of novel FYN kinase inhibitors
#304Polypeptides with improved arabinose transport specificity
#305Compositions and methods involving engineered p27
#306Transgene genetic tags and methods of use
#307COMPOSITIONS TO DISRUPT PROTEIN KINASE A ANCHORING AND USES THEREOF
#308Signal molecules as cell penetration agents
#309Method for generating immune cells resistant to arginine and/or tryptophan depleted microenvironment
#310BCR-ABL variants
#311MODIFICATIONS OF PEPTIDE COMPOSITIONS TO INCREASE STABILITY AND DELIVERY EFFICIENCY
#312Microorganisms and methods for the production of butadiene using acetyl-coA
#313Activation of APC in immunotherapy
#314FGFR3 binding molecules
#315Microorganism with improved L-threonine producing capability, and method for producing L-threonine by using the same
#316Enhanced hAT family transposon-mediated gene transfer and associated compositions, systems, and methods
#317CHIMERIC ANTIGEN RECEPTOR (CAR) SIGNALLING SYSTEM
#318Compositions and methods related to nucleic acid synthesis
#319O-succinyl homoserine transferase variant and method of producing O-succinyl homoserine using the same
#320PKC-activating compounds for the treatment of neurodegenerative diseases
#321Polyphosphate-dependent glucokinase and method for producing glucose 6-phosphate using same
#322OPTIMIZED LENTIVIRAL VECTOR FOR XLA GENE THERAPY
#323Peptides, combination of peptides as targets and for use in immunotherapy against gallbladder cancer and cholangiocarcinoma and other cancers
#324Methods and pharmaceutical composition for the treatment of neurodegenerative disease
#325METHODS AND GENETICALLY MODIFIED CELLS FOR PRODUCTION OF FATTY ACID ESTERS
#326METHODS AND COMPOSITIONS ENHANCING SURVIVAL AND FUNCTIONALITY OF ANTI-TUMOR AND ANTI-VIRAL T CELLS
#327Fusion proteins and methods thereof
#328NTRK1 fusion molecules and uses thereof
#329CDKL5 EXPRESSION VARIANTS AND CDKL5 FUSION PROTEINS
#330Cyclic GMP-chelating peptides for subcellular targeting
#331ROR1 antibody compositions and related methods
#332Mutant Taq polymerase for faster amplification
#333Mutant taq polymerase for amplification in increased salt concentration or body fluids
#334Biosensors for detecting and/or neutralizing bioavailable uranium and related U-sensitive genetic molecular components, gene cassettes, vectors, genetic circuits, compositions, methods and systems
#335TARGETING GDF6 AND BMP SIGNALING FOR ANTI-MELANOMA THERAPY
#336ACTIVATING MITOTIC CHECKPOINT CONTROL MECHANISMS
#337Fully-human t-cell receptor specific for the 369-377 epitope derived from the Her2/neu (ERBB2) receptor protein
#338Substituted 6,11-dihydro-5H-benzo[B]carbazoles as inhibitors of ALK and SRPK
#339Peptides for treatment and prevention of hyperglycaemia
#340Productivity and Bioproduct Formation in Phototropin Knock/Out Mutants in Microalgae
#341Methods for treating anemia in a subject in need thereof
#342TATk-CDKL5 fusion proteins, compositions, formulations, and use thereof
#343Methods for treating anemia in a subject in need thereof
#344Methods for treating anemia in a subject in need thereof
#345ISOLATED GDF TRAP POLYPEPTIDE
#346SOLUBLE FIBROBLAST GROWTH FACTOR RECEPTOR 3 (FGR3) POLYPEPTIDE FOR USE IN THE PREVENTION OR TREATMENT OF SKELETAL GROWTH RETARDATION DISORDERS
#347Peptides, combination of peptides as targets and for use in immunotherapy against gallbladder cancer and cholangiocarcinoma and other cancers
#348DNA vectors, transposons and transposases for eukaryotic genome modification
#349Fusion proteins and methods thereof
#350Optogenetic construct for allosteric control of protein activity
#351CONJUGATE VACCINE USING TRIMMING FUNCTION OF ERAP1
#352Ligand binding molecules and uses thereof
#353ISOLATED GDF TRAP POLYPEPTIDE
#354Ex vivo method of generating super regulatory T cells for the prevention of autoimmune disease
#355Methods and compositions for reducing serum lipids
#356Exosome-based anticancer agent
#357APPARATUS AND METHOD FOR DETECTING CANINE CANCER
#358Enzyme products
#359BIFIDOBACTERIUM LONGUM
#360HLA-A2 subtype-specific PLK1-derived epitope inducing antigen-specific t cell immune response to PLK1 protein
#361REPROSOMES, AS EXOSOMES CAPABLE OF INDUCING REPROGRAMMING OF CELLS AND PREPARATION METHOD THEREOF
#362TRANSLOCATION AND MUTANT ROS KINASE IN HUMAN NON-SMALL CELL LUNG CARCINOMA
#363Method for producing 3-fucosyllactose using
#364Multipartite signaling proteins and uses thereof
#365MULTIPARTITE SIGNALING PROTEINS AND USES THEREOF
#366CHIMERIC ENGULFMENT RECEPTOR MOLECULES
#367Cell
#368Genetic construct
#369Fusion proteins and methods thereof
#370Methods of improving mycorrhization in plants and genetically modifed plants with improved mycorrhization
#371Peptides, combination of peptides as targets and for use in immunotherapy against gallbladder cancer and cholangiocarcinoma and other cancers
#372Treatment of retinitis pigmentosa
#373Peptides, combination of peptides as targets and for use in immunotherapy against gallbladder cancer and cholangiocarcinoma and other cancers
#374Assays using arrestin recruitment and unmodified receptors
#375Peptide based inhibitors of Raf kinase protein dimerization and kinase activity
#376Synthesis of fucosylated compounds
#377ALK7:actriib heteromultimers and uses thereof
#378Heteroaryl compounds and uses thereof
#379Methods and compounds for the treatment or prevention of severe influenza
#380AMINO-PYRROLOPYRIMIDINONE COMPOUNDS AND METHODS OF USE THEREOF
#381FGFR GATEKEEPER MUTANT GENE AND DRUG TARGETING SAME
#382Apparatus for high density information storage in molecular chains
#383ACTRIIB-FC POLYNUCLEOTIDES, POLYPEPTIDES, AND COMPOSITIONS
#384METHOD FOR IMPROVING SALT TOLERANCE OF PLANT
#385Membrane span-kinase fusion protein and the uses thereof
#386DNA Vectors, Transposons And Transposases For Eukaryotic Genome Modification
#387Peptide directed protein knockdown
#388Process for the production of fucosylated oligosaccharides
#389Modified RNA polymerase sigma factor 70 polypeptide
#390Glycerol free ethanol production
#391SIGNAL TRANSDUCTION MODIFYING PROTEIN
#392NOVEL ISOFORM OF ANAPLASTIC LYMPHOMA KINASE AND ITS USES
#393Peptides, combination of peptides as targets and for use in immunotherapy against gallbladder cancer and cholangiocarcinoma and other cancers
#394Truncated epiderimal growth factor receptor (EGFRt) for transduced T cell selection
#395Anti-TIE2 antibodies and uses thereof
#396Methods and compositions for treating melanoma
#397PKC-activating compounds for the treatment of neurodegenerative diseases
#398Mammalian cells devoid of lactate dehydrogenase activity
#399Method of amplifying circular DNA
#400Drug regulated transgene expression
#401TGF-beta superfamily type I and type II receptor heteromultimers and uses thereof
#402Nucleic acid encoding angiopoietin-2 specific Tie2 receptor
#403RNA virus vectors carrying DAI and RIPK3
#404Increasing plant oil content by improving activity of acetyl-CoA carboxylase
#405Thermostable tagatose-6-phosphate phosphatase and a method for producing tagatose using the same
#406Fusion proteins and methods thereof
#407Methods of sensitizing cancer to immunotherapy
#408Hepatitis B virus (HBV) vaccines and uses thereof
#409Method for detecting nucleotide polymorphisms
#410Cytoplasmic protein complex comprising a kinase substrate sensor, cells comprising the complex, and associated detection methods
#411DNA Vectors, Transposons And Transposases For Eukaryotic Genome Modification
#412Human serum albumin binding compounds and fusion proteins thereof
#413Methods for predicting kinase inhibitor resistance
#414Genetically modified rat comprising a humanized locus
#415BTK mutation and ibrutinib resistance
#416Structure, manufacturing and uses of human-derived cell-permeable peptides conjugated with specific biologically active cargo peptides
#417Regulation of fungal fruiting body development
#419Cell-based assay for determining activity in the retinoblastoma pathway
#420Genetically modified microorganisms
#421C-RAF Mutants that Confer Resistance to RAF Inhibitors
#422MK2 inhibitors and uses thereof
#423Methods for treating heart failure using beta-ARKnt peptide
#424Compositions for detecting mutant anaplastic lymphoma kinase in lung cancer
#425Identifying ligands for bacterial sensors
#426METHOD FOR PRODUCING 3-HYDROXYPROPIONIC ACID AND OTHER PRODUCTS
#427Truncated Constructs Related To RIPK3
#428CYCLIN A1-TARGETED T-CELL IMMUNOTHERAPY FOR CANCER
#429TUMOR ANTIGEN PEPTIDE
#430Multipartite signaling proteins and uses thereof
#431Methods and compositions for generating doubled haploid plants and use of same in breeding
#432FUNCTIONAL LIGANDS TO PEPTIDES
#433CYCLIN-DEPENDENT KINASE 5 (CDK5) INHIBITORY PEPTIDES
#434COMPOSITIONS AND METHOD FOR MANIPULATING PIM-1 ACTIVITY IN CIRCULATORY SYSTEM CELLS
#435DIMERIZATION SWITCHES AND USES THEREOF
#436Transgenic mouse model of retinal vascular disease, method of making, and method of using
#437BIOLOGICAL FERMENTATION USING DIHYDROXYACETONE AS A SOURCE OF CARBON
#438Fusions and method for detecting same
#439Methods for delivering cargo into a cell by using signal molecules as cell penetration agents
#440MIC-1 receptor and uses thereof
#441METHODS FOR EXTENDING THE REPLICATIVE CAPACITY OF SOMATIC CELLS DURING AN EX VIVO CULTIVATION PROCESS
#442DNA VECTORS, TRANSPOSONS AND TRANSPOSASES FOR EUKARYOTIC GENOME MODIFICATION
#443MODIFICATIONS OF PEPTIDE COMPOSITIONS TO INCREASE STABILITY AND DELIVERY EFFICIENCY
#444THIOSULFATE BIOSENSOR FOR GUT INFLAMMATION
#445Methods for reducing LRRK2 expression
#446Expression of novel cell tags
#447Composition and methods for inhibiting mammalian sterile 20-like kinase 1
#448ANTI-INFLUENZA VIRUS AGENT AND SCREENING METHOD FOR ANTI-INFLUENZA VIRUS AGENT
#449ALK and NTRK1 fusion molecules and uses thereof
#450UV Associated mtDNA Fusion Transcripts and Methods and Uses Thereof
#451ROR1 antibody compositions and related methods
#452Compositions and methods for modulating kinase activity
#453Synthetic hybrid receptor and genetic circuit in bacteria to detect enteric pathogenic microorganisms
#454Enhanced hAT family transposon-mediated gene transfer and associated compositions, systems, and methods
#455TATk-CDKL5 fusion proteins, compositions, formulations, and use thereof
#456TREATMENT OF OCULAR NEOVASCULARIZATION USING ANTI-VEGF PROTEINS
#457BMP-ALK3 ANTAGONISTS AND USES FOR PROMOTING BONE GROWTH
#458PYRIDONE DERIVATIVES AND THEIR USE AS KINASE INHIBITORS
#459TPM4-ALK fusion protein and composition for diagnosing cancer
#460DNA polymerase possessing continuous catalytic capacity and salt tolerance
#461Substituted indazole derivatives active as kinase inhibitiors
#462FGFR3 binding molecules
#463TREATMENT OF RETINITIS PIGMENTOSA
#464Fusion protein crystal comprising a moiety
#465Gene Expression Cassette And Product Thereof
#466NITRATE BIOSENSOR
#467sp. microorganisms having l-lysine-producing ability and l-lysine producing method using same
#468DNA vectors, transposons and transposases for eukaryotic genome modification
#469Substituted 6,11-dihydro-5H-benzo[b]carbazoles as inhibitors of ALK and SRPK
#470Compositions and Methods for the Diagnosis of Retinal Neovascularization
#471Genetically engineered drug resistant T cells and methods of using the same
#472Enhanced hAT Family Transposon-Mediated Gene Transfer and Associated Compositions, Systems, and Methods
#473METHODS FOR IN VITRO PRODUCTION OF PLATELETS AND COMPOSITIONS AND USES THEREOF
#474HIV kinase variants
#475Enhanced hAT family transposon-mediated gene transfer and associated compositions, systems and methods
#476SRM Assay to Indicate Cancer Therapy
#477Productivity and bioproduct formation in phototropin knock/out mutants in microalgae
#478Method for producing phytosphingosine or sphinganine
#479Redirected cells with MHC chimeric receptors and methods of use in immunotherapy
#480METHODS FOR IMPROVING FUNCTIONALITY IN NK CELL BY GENE INACTIVATION USING SPECIFIC ENDONUCLEASE
#481Gene expression in Bacteroides
#482ALK4.ActRIIB heteromultimers
#483Recombinant proteins and their therapeutic uses
#484MICROORGANISMS FOR THE PRODUCTION OF 1,4-BUTANEDIOL
#485Protein standard compositions and methods of making and using the same
#486Treatment of ocular neovascularization using anti-VEGF proteins
#487Receptor tyrosine kinase biomarkers
#488Switchable non-scFv chimeric receptors, switches, and methods of use thereof to treat cancer
#489CSF1 THERAPEUTICS
#490PINK1 C-terminal domain polypeptide and methods using the same in cancer treatment
#491METHOD FOR REGULATION OF TELOMERE LENGTH
#492Necroptosis Signaling as a Therapeutic Target for Alzheimer's Disease
#493Immunogenic Fusion Proteins For The Treatment Of Cancer
#494Method for producing an ActRIIB-Fc fusion polypeptide
#495Amino-pyrrolopyrimidinone compounds and methods of use thereof
#496Fungal strains and methods of use
#497Method for secretory production of protein
#498Microorganism with enhanced L-lysine producibility and method for producing L-lysine using the same
#499Modified AXL peptides and their use in inhibition of AXL signaling in anti-metastatic therapy
#500FUSION PROTEINS AND METHODS THEREOF
#501Fully-human T-cell receptor specific for the 369-377 epitope derived from the Her2/neu (ERBB2) receptor protein
#502Composition and method for affecting the binding of antigen-binding polypeptides to antigens
#503Protein kinase C inhibitors and uses thereof
#504Azabenzimidazole derivatives as agonists of the AMP-activated protein kinase
#505Compositions and methods related to nucleic acid synthesis
#506Heteroaryl compounds and uses thereof
#507DAGRS: directed antigonists to cancer cell growth signals
#508Toolkit for the production of post-translationally modified proteins
#509Method and compositions for cellular immunotherapy
#510Compositions and methods of increasing longevity or treating cellular stress
#511BCR-ABL variants
#512Virus Vectors Expressing Multiple Epitopes of Tumor Associated Antigens For Inducing Antitumor Immunity
#513MULTILAMELLAR LIPID VESICLE COMPOSITIONS INCLUDING A CONJUGATED ANAPLASTIC LYMPHOMA KINASE (ALK) VARIANT AND USES THEREOF
#514MOLECULAR SENSORS
#515ENHANCED PROTEIN EXPRESSION
#516Engineered programmable molecular scaffolds from porous protein crystals
#517Ligand binding molecules and uses thereof
#518NEW C-GLYCOSYLPOLYPHENOL ANTIDIABETIC AGENTS, EFFECT ON GLUCOSE TOLERANCE AND INTERACTION WITH BETA-AMYLOID. THERAPEUTIC APPLICATIONS OF THE SYNTHESIZED AGENT(S) AND OF GENISTA TENERA ETHYL ACETATE EXTRACTS CONTAINING SOME OF THOSE AGENTS
#519Peptides, combination of peptides as targets and for use in immunotherapy against gallbladder cancer and cholangiocarcinoma and other cancers
#520CAMKK1 as a novel regenerative therapeutic
#521HBV RNAse H purification and enzyme inhibitors
#522METHODS AND COMPOSITIONS FOR TREATING INEFFECTIVE ERYTHROPOIESIS
#523Method for treatment of metastatic and refractory cancers and tumors with an inducer that overcomes inhibition of T cell proliferation
#524Method of amplifying circular DNA
#525METHOD FOR SCREENING COMPOUND SPECIFICALLY SUPPRESSING FORMATION OF CAVEOLAE OF CANCER CELLS, SCREENING KIT, VECTOR AND TRANSFORMANT TO BE USED IN KIT, AND METHOD FOR SELECTING PATIENT FOR WHOM MOLECULARLY TARGETED DRUG IS INDICATED
#526Measuring method and composition using kinase
#527Protein with recombinase activity for site-specific DNA-recombination
#528Conditionally active heterodimeric polypeptides and methods of use thereof
#529MTOR kinase mutations and methods of use thereof
#530HUMAN BETA-ADRENERGIC RECEPTOR KINASE POLYPEPTIDE AND METHODS
#531Method for forming a reversible protein nanocluster using light in a cell
#532Methods of diagnosing and treating cancer in patients having or developing resistance to a first cancer therapy
#533ERK1 and ERK2 mutations that confer resistance to MAPK pathway inhibitors
#534Transgene genetic tags and methods of use
#535T-cell redirecting bispecific antibodies for treatment of disease
#536One class of pyrazolone compounds and use thereof
#537ERK-derived peptides and uses thereof
#538Prokaryotic 2-component signaling pathways for use as logic gates in mammalian cells
#539Ligand-directed covalent modification of protein
#540Fluorescent AMP-kinase biosensors
#541Modified microorganisms comprising an optimized system for oligosaccharide utilization and methods of using same
#542C-RAF Mutants that Confer Resistance to RAF Inhibitors
#543Methods of identifying ActRIIB variants
#544Genetically encoded fluorescent sensors for detecting intracellular signalling through diacylglycerol pathways
#545NUCLEOTIDE REPEAT EXPANSION-ASSOCIATED POLYPEPTIDES AND USES THEREOF
#546Microorganisms and methods for the production of butadiene using acetyl-CoA
#547Bicyclic pyrazolone compounds and methods of use
#548Anti-TIE2 antibodies and uses thereof
#549DUAL CONTROLS FOR THERAPEUTIC CELL ACTIVATION OR ELIMINATION
#550Modular Method to Prepare Tetrameric Cytokines with Improved Pharmacokinetics by the Dock-and-Lock (DNL) Technology
#551IMIDAZO[4,5-C]QUINOLINES AS DNA-PK INHIBITORS
#552Immunogenic Polypeptide Composed of HLA-B7 Restricted Tumor Antigen-Derived Optimized Cryptic Peptides, and Uses Thereof
#553USE OF ACTIVIN RECEPTOR-LIKE KINASE 1 (ALK-1) ANTAGONISTS IN THE TREATMENT OF CANCER
#554Drug regulated transgene expression
#555Calcium reporter gene
#556METHODS AND PRODUCTS RELATING TO GSK3ß REGULATION
#557TRUNCATED VARIANT OF THE MAMMALIAN TARGET FOR RAPAMYCIN (mTOR) PROTEIN
#558METHODS AND COMPOSITIONS FOR TREATING INEFFECTIVE ERYTHROPOIESIS
#559Mps1 and KNL1 phosphorylation system
#560Methods for Generating Stably Linked Complexes Composed of Homodimers, Homotetramers or Dimers of Dimers and Uses
#561PYRIMIDINE SUBSTITUTED PURINE COMPOUNDS AS KINASE (S) INHIBITORS
#562Method for detection of a TECR:PKN1 or an ANXA4:PKN1 gene fusion
#563Method for producing 3-hydroxypropionic acid and other products
#564ISOLATED NUCLEIC ACIDS AND QUANTITATIVE TRAIT LOCI (QTL) FROM S. HABROCHAITES AND METHODS OF USE THEREOF FOR INCREASING RESISTANCE TO BACTERIAL SPECK DISEASE IN TOMATO AND OTHER PLANTS
#565Methods of cancer therapy by inhibiting fusion polypeptides comprising fibroblast growth factor receptor 2 (FGFR2) and vinculin (VCL)
#566DNA vectors, transposons and transposases for eukaryotic genome modification
#567DNA vectors, transposons and transposases for eukaryotic genome modification
#568DNA vectors, transposons and transposases for eukaryotic genome modification
#569DNA vectors, transposons and transposases for eukaryotic genome modification
#570Benzimidazole analogues and related methods
#571IN SITU REACTION DEVICE
#572Xylose utilizing oleaginous yeast
#573RAF gene fusions
#574Antibody-fynomer conjugates
#575Green microalgae lacking a functional DYRKP-1 gene, for use for increased production of feedstock
#577INDOLE-LIKE TRK RECEPTOR ANTAGONISTS
#578Tetrameric cytokines with improved biological activity
#579Method for generating immune cells resistant to arginine and/or tryptophan depleted microenvironment
#580Isoform of anaplastic lymphoma kinase and its uses
#581T-cell redirecting bispecific antibodies for treatment of disease
#582Protein with recombinase activity for site-specific DNA-recombination
#583Chimeric antigen receptor (CAR) signalling system
#584Peptides and methods and uses thereof for preventing retinal disorders
#585Modified RNA polymerase sigma factor 70 polypeptide
#586DNA polymerase possessing continuous catalytic capacity and salt tolerance
#587Substrate-mimetic AKT inhibitor
#588COMPOSITIONS AND METHODS FOR THE TREATMENT OF HER2/NEU OVER-EXPRESSING TUMORS
#589RECURRENT FUSION GENES IDENTIFIED IN HIGH -GRADE SEROUS OVARIAN CARCINOMA
#590ERK-derived peptides and uses thereof
#591Multimeric Complexes with Improved in Vivo Stability, Pharmacokinetics and Efficacy
#592Mutant-selective EGFR inhibitors and uses thereof
#593Method for assaying a protease
#594Nucleotide sequences encoding VEGF antagonist compositions of FLT-1 and uses thereof
#595Immunogenic fusion proteins for the treatment of cancer
#596COMPOSITIONS AND METHOD FOR MANIPULATING PIM-1 ACTIVITY IN CIRCULATORY SYSTEM CELLS
#597Assay for Detection of Transient Intracellular CA2+
#598ACTIVIN-ACTRIIA ANTAGONISTS FOR INHIBITING GERM CELL MATURATION
#599NOVEL FUSION GENES AS FACTORS RESPONSIBLE FOR GASTRIC CANCER
#600FGFR gatekeeper mutant gene and drug targeting same