108915 ⎘
Enzymes; Proenzymes; Compositions thereof ; Processes for preparing, activating, inhibiting, separating or purifying enzymes; Transferases (2.) transferring phosphorus containing groups, e.g. kinases (2.7)
Mutant NNK1 allele and its use
#602ASSAY TO DETERMINE LRRK2 ACTIVITY IN PARKINSON'S DISEASE
#603Multipartite signaling proteins and uses thereof
#604HETEROARYL COMPOUNDS AND USES THEREOF
#605Substituted indazole derivatives active as kinase inhibitiors
#606TOPK peptides and vaccines including the same
#607Substituted indazole derivatives active as kinase inhibitiors
#608TGF-beta superfamily type I and type II receptor heteromultimers and uses thereof
#609ALK7:ActRIIB heteromultimers and uses thereof
#610NOVEL CHIMERIC GENE ATF7IP-PDGFRB OF ACUTE LYMPHOBLASTIC LEUKEMIA
#611ULK1 COMPOSITIONS, INHIBITORS, SCREENING AND METHODS OF USE
#612FLUORESCENT PROTEIN BIOSENSORS TO PROBE THE CONFORMATIONAL ACTIVATION OF CDK/CYCLIN KINASES
#613Nucleic acid sequence segment for enhancing protein expression
#614Polynucleotides encoding BREX system polypeptides and methods of using same
#615TARGETING GDF6 AND BMP SIGNALING FOR ANTI-MELANOMA THERAPY
#616Protein kinase C inhibitors and uses thereof
#617Aminoisoquinoline Derivatives as Protein Kinase Inhibitors
#618Cysteine-reactive ligand discovery in proteomes
#619Heteroaryl compounds and uses thereof
#620Translocation and mutant ROS kinase in human non-small cell lung carcinoma
#621Modifications of peptide compositions to increase stability and delivery efficiency
#622RECOMBINANT PROTEINS AND THEIR THERAPEUTIC USES
#623FLT4 (VEGFR-3) AS A TARGET FOR TUMOR IMAGING AND ANTI-TUMOR THERAPY
#624TATk-CDKL5 fusion proteins, compositions, formulations, and use thereof
#625Anaplastic Lymphoma Kinase (ALK) As An Oncogene Capable Of Transforming Normal Human Cells
#626Compositions for detecting mutant anaplastic lymphoma kinase in lung cancer
#627Method for decreasing the body fat content in a subject by administering an ActRIIB protein
#628T-cell redirecting bispecific antibodies for treatment of disease
#6293,5-diaminopyrazole kinase inhibitors
#630Truncated Constructs of RIPK3 and Related Uses
#631BIOMARKERS, METHODS AND KITS FOR THE DIAGNOSIS OF RHEUMATOID ARTHRITIS
#632Parthenogenic activation of human oocytes for the production of neuronal cells
#633Dosage compensating transgenes and cells
#634Muscle specific tyrosine kinase-fluorophore conjugate compositions, kits and methods of using
#635Structure, manufacturing and uses of human-derived cell-permeable peptides conjugated with specific biologically active cargo peptides
#636Methods and systems for predicting misfolded protein epitopes
#637Method for producing polypeptides using PDK-inactivated cells
#638Compositions and methods for specific regulation of pyruvate dehydrogenase kinase
#639Visualization of P-TEFb by Fluorescence Complementation
#640Recombinant microorganism metabolizing 3,6-anhydride-L-galactose and a use thereof
#641Composition for preventing or treating autoimmune disease, comprising, as active ingredient, PINK1 protein or polynucleotide encoding same
#642Method for increasing pathogen resistance in plants
#643Fusion proteins and methods thereof
#644ACTRIIB-FC POLYNUCLEOTIDES, POLYPEPTIDES, AND COMPOSITIONS
#645Inhibition of AXL Signaling in Anti-Metastatic Therapy
#646MELK epitope peptides and vaccines containing the same
#647Human serum albumin binding compounds and fusion proteins thereof
#648MODULATION OF REGULATORY T CELL FUNCTION VIA PROTEIN KINASE C-eta
#649ANTI-CD19 COMPOSITIONS AND METHODS FOR TREATING CANCER
#650Selective Sensitization of Cancer Cells to, and Selective Protection of Non-Cancer Cells from Genotoxic Therapies
#651PKC-activating compounds for the treatment of neurodegenerative diseases
#652MICROORGANISMS FOR THE PRODUCTION OF 1,4-BUTANEDIOL
#653Conjugate vaccine using trimming function of ERAP1
#654CSF1 THERAPEUTICS
#655Compounds and methods for producing a conjugate
#656USE OF ANTI-ERBB2 VACCINES IN ASSOCIATION WITH AN ELECTRIC FIELD
#657Glycosylated VEGF decoy receptor fusion protein
#658Genetically engineered and acid-resistant yeast cell with enhanced activity of radiation sensitivity complementing kinase and method of producing lactate by using the yeast cell
#659Method of treating eye disease using glycosylated VEGF decoy receptor fusion protein
#660Artificial synthetic cDNA and method for detecting secondary glioblastoma
#661HER2/Neu cancer vaccine
#662Method of Forming Fragment Ligated Inhibitors
#663FUSION POLYNUCLEOTIDES AND FUSION POLYPEPTIDES ASSOCIATED WITH CANCER AND PARTICULARLY MELANOMA AND THEIR USES AS THERAPEUTIC AND DIAGNOSTIC TARGETS
#664Genetically encoded fluorescent sensors for detecting intracellular signalling through diacylglycerol pathways
#665GENES FOR IMPROVING NUTRIENT UPTAKE AND ABIOTIC STRESS TOLERANCE IN PLANTS
#666VEGFR-3 ligand binding molecules and uses thereof
#667SRM assay to indicate cancer therapy
#668Method for controlling length of overhang of double stranded DNA
#669MK2 inhibitors and uses thereof
#670Methods and Compositions for Generating Bioactive Assemblies of Increased Complexity and Uses
#671Methods of treating cholangiocarcinoma
#672Growth arrested cells useful for producing compounds
#673MELK regulation for the treatment of breast cancer
#674Soluble fibroblast growth factor receptor 3 (FGR3) polypeptide for use in the prevention or treatment of skeletal growth retardation disorders
#675A Soluble Fibroblast Growth Factor Receptor 3 (FGR3) Polypeptide For Use In The Prevention Or Treatment Of Skeletal Growth Retardation Disorders
#676UV Associated mtDNA Fusion Transcripts and Methods and Uses Thereof
#677Angiopoietin-2 specific TIE2 receptor
#678HBV RNASE H PURIFICATION AND ENZYME INHIBITORS
#679Fibrotic non-human animal, and use thereof
#680Fragment ligated inhibitors selective for the polo box domain of PLK1
#681Modified AXL peptides and their use in inhibition of AXL signaling in anti-metastatic therapy
#682Inhibition of AXL Signaling in Primary Tumor Therapy
#683PLANTS WITH ALTERED ROOT ARCHITECTURE, RELATED CONSTRUCTS AND METHODS INVOLVING GENES ENCODING LEUCINE RICH REPEAT KINASE (LLRK) POLYPEPTIDES AND HOMOLOGS THEREOF
#684USE OF ACTIVIN RECEPTOR-LIKE KINASE 1 (ALK-1) ANTAGONISTS IN THE TREATMENT OF CANCER
#685COMPOUNDS USEFUL AS INHIBITORS OF ATR KINASE
#686IMIDE-BASED MODULATORS OF PROTEOLYSIS AND ASSOCIATED METHODS OF USE
#687Compositions and Methods for the Diagnosis of Retinal Neovascularization
#688Method for forming a reversible protein nanocluster using light in a cell
#689Multipartite signaling proteins and uses thereof
#690BMP-ALK3 antagonists and uses for promoting bone growth
#691Peptide directed protein knockdown
#692Methods of treating hemoglobinopathies
#693Model animal for pregnancy-induced hypertension syndrome, and treatment method therefor
#694PLANTS HAVING ENHANCED YIELD-RELATED TRAITS AND A METHOD FOR MAKING THE SAME
#695Broad spectrum ErBB ligand binding molecules and methods for preparing and using them
#696TATk-CDKL5 fusion proteins, compositions, formulations, and use thereof
#697Methods and tools for identification of RSK/MSK kinase inhibitors
#698MELANOCORTIN RECEPTOR MUTANT MOUSE AND USES THEREOF
#699Production of organic acids by fermentation of genetically engineered yeast cells at low pH
#700Use of a Receptor Kinase Having LysM Motifs in Order to Improve the Response of Plants to Lipochitooligosaccharides
#701Anaplastic lymphoma kinase (ALK) as oncoantigen for lymphoma vaccination
#702Mutations In Calmodulin Genes
#703Methods and peptides for preventing and treating a BCR-ABL and a C-ABL associated disease
#704FUSION PROTEIN FOR ACTIVATING RTK SIGNAL TRANSMISSION BY MEANS OF LIGHT, AND USE THEREOF
#705Method for engineering proteases and protein kinases
#706Nucleic acid encoding antibodies binding to the extracellular domain of the receptor tyrosine kinase ALK
#707FUSION PROTEINS AND METHODS THEREOF
#708α/β-peptide mimics of Z-domain peptides
#709FGFR2 FUSION GENE
#710Mutations associated with resistance to inhibitors of Bruton's Tyrosine Kinase (BTK)
#711AXL TYROSINE KINASE INHIBITORS AND METHODS OF MAKING AND USING THE SAME
#712Truncated epiderimal growth factor receptor (EGFRt) for transduced T cell selection
#713FUSION GENE OF CEP55 GENE AND RET GENE
#714Over-expression of GCN2-Type Protein Kinase in Plants
#715Protein with recombinase activity for site-specific DNA-recombination
#716Methods and products relating to GSK3β regulation
#717METHOD FOR HARVESTING ORGANIC COMPOUNDS FROM GENETICALLY MODIFIED ORGANISMS
#718Animal model for epilepsy and method for producing the same
#719Cancer stem cell targeted cancer vaccines
#720C-RAF mutants that confer resistance to RAF inhibitors
#721AMPK activator screening method, and AMPK activator
#722BROAD SPECTRUM ERBB LIGAND BINDING MOLECULES AND METHODS FOR THEIR USE
#723Crystal Structure of a NEF/SdAb19 Complex and Uses Thereof
#724METHODS FOR TREATING AND MONITORING THE STATUS OF CANCER
#725Brain somatic mutations associated to epilepsy and uses thereof
#726Goodpasture Antigen Binding Protein and Its Detection
#727Methods for generating stably linked complexes composed of homodimers, homotetramers or dimers of dimers and uses
#728Composition and method for diagnosis and immunotherapy of lung cancer
#729Binding molecules with antitumoral activity
#730Fluorescent protein-based calcium integrators
#731PCR reaction mixtures with decreased non-specific activity
#732Mutant-selective EGFR inhibitors and uses thereof
#733Dock-and-lock (DNL) complexes for therapeutic and diagnostic use
#734Membrane span-kinase fusion protein and the uses thereof
#735Methods and compositions for generating bioactive assemblies of increased complexity and uses
#736Substrate-mimetic Akt inhibitor
#737Recombinant PRPK-TPRKB and uses thereof
#738Treatment of ocular neovascularization using anti-VEGF proteins
#739Synthetic Epigallocatechin Gallate (EGCG) Analogs
#7405- or 6-substituted benzofuran-2-carboxamide compounds and methods for using them
#741Biosensor for detecting RAF/KSR family kinase dimerization and uses thereof
#742TREATMENT OF AMD USING AAV SFLT-1
#743Peptides and methods and uses thereof for preventing retinal disorders
#744Method and apparatus for measuring phosphorylation kinetics on large arrays
#745HUMAN BETA-ADRENERGIC RECEPTOR KINASE POLYPEPTIDE AND METHODS
#746Biocatalysts with enhanced inhibitor tolerance
#747TREATMENT OF AMD USING AAV SFLT-1
#748ALK and NTRK1 fusion molecules and uses thereof
#749Azaindoles useful as inhibitors of Janus kinases
#750INCREASED PRODUCTION OF SECRETED PROTEINS BY RECOMBINANT EUKARYOTIC CELLS
#751Protein kinase C inhibitors and uses thereof
#752Cyclin A1-targeted T-cell immunotherapy for cancer
#753THERMOSTABLE ASSAY REAGENTS
#754Compositions and methods for specific regulation of pyruvate dehydrogenase kinase
#755Dosage compensating transgenes and cells
#756Compositions and methods for augmenting permeability barriers
#757Recombinant proteins and their therapeutic uses
#758Non-natural ribonuclease conjugates as cytotoxic agents
#759Bacterial methods
#760Structural mutations in titin cause dilated cardiomyopathy
#761Methods and compositions for detecting and modulating O-glycosylation
#762COMPOSITIONS AND METHODS FOR CaMKII INHIBITORS AND USES THEREOF
#763Chymase binding compounds and medical uses thereof
#764METHODS AND COMPOSITIONS FOR DETECTING AND MODULATING A NOVEL MTOR COMPLEX
#765Screening method for BRAF inhibitors
#766Peptide mimetic ligands of polo-like kinase 1 polo box domain and methods of use
#767POLYNUCLEOTIDES ENCODING PROTEINS INVOLVED IN PLANT METABOLISM
#768Nucleic Acid Encoding a Brain Derived Tau Kinase Polypeptide and Methods of Use Thereof
#769TRUNCATED VARIANT OF THE MAMMALIAN TARGET FOR RAPAMYCIN (mTOR) PROTEIN
#770DIRECT NUCLEIC ACID AMPLIFICATION KIT, REAGENT AND METHOD
#771Tumor antigen proteins or genes of polo-like kinase 1
#772LYSM RECEPTOR-LIKE KINASES TO IMPROVE PLANT DEFENSE RESPONSE AGAINST FUNGAL PATHOGENS
#773Method for detecting neurological disease associated with cognitive impairment by measuring EphA4 extracellular domain
#774Prodrug anti-cancer therapy
#775Bisubstrate fluorescent probes for protein kinase CK2
#776Reverse transcriptase having improved thermostability
#777Method for producing epithelial stem cells
#778Method for Cellular RNA Expression
#779Cytoplasmic protein complex comprising a kinase substrate sensor cells and associated detection methods
#780Compositions and methods for treating cancer
#781Method for engineering proteases and protein kinases
#782CHIMERIC PDK1 KINASES
#783Non-natural ribonuclease conjugates as cytotoxic agents
#784Modified photosynthetic microorganisms for producing lipids
#785Proteins that efficiently generate singlet oxygen
#786VEGF antagonist compositions and uses thereof
#787Plants with increased activity of a starch phosphorylating enzyme
#788Glycogen synthase kinase-3 inhibitors
#789Growth-regulated viral vector containing the aurora kinase promoter
#790Manipulation of HSP70 and IRE1Alpha Protein Interactions
#791VEGF-activated trail ligands
#792Methods and compositions for the diagnosis and treatment of cancer resistant to anaplastic lymphoma kinase (ALK) kinase inhibitors
#793METHOD OF PREVENTING PROGRESSION OF HYPERTENSION-INDUCED HEART FAILURE WITH PKC PEPTIDES
#794COMPOSITION AND METHODS FOR THE DIAGNOSIS AND TREATMENT OF TUMOR
#795EGFR-related polypeptides and methods of use
#796Activin-actriia antagonists for treating a follicle-stimulating horomone-secreting pituitary tumor
#797Fusion protein for antagonizing angiogenesis inducible factors and uses thereof
#798PRODUCTION OF SECRETED PROTEINS BY FILAMENTOUS FUNGI
#799Method of efficiently establishing induced pluripotent stem cells
#800Truncated ACTRIIB-FC fusion protein
#801Dihydro-benzo-oxazine and dihydro-pyrido-oxazine derivatives
#802Methods and compositions for kinase inhibition
#803COMPOSITIONS AND METHODS OF USE OF MITOGEN-ACTIVATED PROTEIN KINASE KINASE KINASE
#804Fusion protein comprising C-terminal domain of RET protein and use thereof as a diagnosing marker
#805NUCLEOTIDE REPEAT EXPANSION-ASSOCIATED POLYPEPTIDES AND USES THEREOF
#806Inhibition of AXL signaling in anti-metastatic therapy
#807Prophylactic or ameliorating agent for genetic diseases
#808Assay for detection of transient intracellular Ca
#809MICROORGANISMS FOR THE PRODUCTION OF 1,4-BUTANEDIOL
#810ACTRIIB-FC polynucleotides, polypeptides, and compositions
#811Methods of Diagnosing and Treating Cancer in Patients Having or Developing Resistance to a First Cancer Therapy
#812Antibodies to human β-adrenergic receptor kinase
#813ULK1 COMPOSITIONS, INHIBITORS, SCREENING AND METHODS OF USE
#814BLADDER CANCER BIOMARKER AND TEST METHOD USING THE SAME
#815Polynucleotides encoding proteins involved in plant metabolism
#816BRAF mutations conferring resistance to BRAF inhibitors
#817Truncated epiderimal growth factor receptor (EGFRt) for transduced T cell selection
#818MOUSE MODEL FOR AVM
#819Broad spectrum ErbB ligand binding molecules and methods for preparing and using them
#820Novel Kinase Inhibition Models and Their Uses
#821PCR reaction mixtures with decreased non-specific activity
#822Inhibition of activated cdc42-associated kinase 1
#823HETEROCYCLIC COMPOUNDS AS MEK INHIBITORS
#824Labelling of fusion proteins with synthetic probes
#825Methods of treating cancer by administering an Axl ligand-binding portion of an Axl tyrosine kinase receptor extracellular domain
#826Pyrazole compounds and thiazole compounds as protein kinases inhibitors
#827Transcription factor-based biosensors for detecting dicarboxylic acids
#828ZINC FINGER NUCLEASE MODIFICATION OF LEUCINE RICH REPEAT KINASE 2 (LRRK2) MUTANT FIBROBLASTS AND IPSCS
#829Fragment ligated inhibitors selective for the polo box domain of PLK1
#830Methods for generating stably linked complexes composed of homodimers, homotetramers or dimers of dimers and uses
#831Method for treatment of inflammatory disease and disorder
#832RAF DIMERS AND USES THEREOF
#833Compositions and Methods for Modulation of Bone Density and Biomineralization
#834Generation of an autologous stem cell library from human oocytes parthenogenetically activated by high or low oxygen tension
#835Modifications of peptide compositions to increase stability and delivery efficiency
#836Azaindoles useful as inhibitors of janus kinases
#837Mutant-selective EGFR inhibitors and uses thereof
#838PKC-activating compounds for the treatment of neurodegenerative diseases
#839Pyrimidine substituted purine compounds as kinase (S) inhibitors
#840AKT phosphorylation at Ser473 as an indicator for taxane-based chemotherapy
#841RAF gene fusions
#842Plants with altered root architecture, related constructs and methods involving genes encoding leucine rich repeat kinase (LLRK) polypeptides and homologs thereof
#843LysM receptor-like kinases to improve plant defense response against fungal pathogens
#844DEVELOPMENT OF FLUORESCENTLY P-LOOP LABELLED KINASES FOR SCREENING OF INHIBITORS
#845Phosphorylation-inhibiting agent or dephosphorylating agent for PTEN
#846NUCLEOTIDE REPEAT EXPANSION-ASSOCIATED POLYPEPTIDES AND USES THEREOF
#847Biomarkers, methods and kits for the diagnosis of rheumatoid arthritis
#848Yield Enhancement in Plants by Modulation of a ZM-CIPK1 Protein
#849Biosynthesis of CMP-legionaminic acid from fructose-6-P, and respective pathway intermediates, using novel GDP-linked precursors
#850Composition and Methods for the Diagnosis and Treatment of Tumor
#851Protein kinase C inhibitors and uses thereof
#852Plants with increased activity of a starch phosphorylating enzyme
#853Isolated GDF trap polypeptide
#854Human β-adrenergic receptor kinase polypeptide and methods
#855PDK inhibitor compounds and methods of use thereof
#856Mutant of the proB gene from coryneform bacteria
#857SYNTHESIS OF FUCOSYLATED COMPOUNDS
#858Microorganisms for the production of 1,4-butanediol
#859EMISSION RATIOMETRIC REPORTERS OF MEMBRANE PDK1 ACTIVATION
#860ACTIVATION OF MUTATED RAC-PK
#861LIGAND-DIRECTED COVALENT MODIFICATION OF PROTEIN
#862Rice gene capable of imparting wide-spectrum disease resistance
#863Methods and compositions for the diagnosis and treatment of cancer resistant to anaplastic lymphoma kinase (ALK) kinase inhibitors
#864Methods and compositions for inhibiting the proliferation of cancer cells
#8654,6-disubstituted pyrimidines useful as kinase inhibitors
#866Gene defects and mutant ALK kinase in human solid tumors
#867Activin-actriia antagonists for inhibiting germ cell maturation
#868System for hot-start amplification via a multiple emulsion
#869Polynucleotides encoding proteins involved in plant metabolism
#870MELK epitope peptides and vaccines containing the same
#871Salinity tolerance in plants
#872Labelling of fusion proteins with synthetic probes
#873BLADDER CANCER BIOMARKER AND TEST METHOD USING THE SAME
#874Methods and compositions for generating bioactive assemblies of increased complexity and uses
#875Goodpasture Antigen Binding Protein and its Detection
#876Generation of modified polymerases for improved accuracy in single molecule sequencing
#877Microorganisms for the production of 1,4-butanediol
#878Method for the diagnosis of the presence of an ovarian cancer
#879Method for treating glioblastoma using antibodies binding to the extracellular domain of the receptor tyrosine kinase ALK
#880Dock-and-lock (DNL) complexes for therapeutic and diagnostic use
#881Methods and products relating to GSK3β regulation
#882Peptides for activation and inhibition of δPKC
#883ORGANIC COMPOUNDS
#88414189, A NOVEL HUMAN KINASE AND USES THEREOF
#885METHODS OF LONG-TERM CULTURE OF EUKARYOTIC CELLS AND USES THEREOF
#886Detection of gleevec resistance
#887Genetic variants in a hypertension susceptibility gene Stk39 and uses thereof
#888Plants with increased activity of a starch phosphorylating enzyme
#889Gene defects and mutant ALK kinase in human solid tumors
#890Axl fusion proteins as Axl tyrosine kinase inhibitors
#891Methods for generating stably linked complexes composed of homodimers, homotetramers or dimers of dimers and uses
#892Cell permeable Nm23 recombinant proteins, polynucleotides encoding the same, and anti-metastatic composition comprising the same
#893Prodrug anti-cancer therapy
#894Compositions and method for manipulating PIM-1 activity in circulatory system cells
#895Isolated nucleic acid encoding a truncated ActRIIB fusion protein
#896Azaindoles useful as inhibitors of Janus kinases
#897Gene defects and mutant ALK kinase in human solid tumors
#898Methods and compositions for detections and modulating O-glycosylation
#899Method of preventing progression of hypertension-induced heart failure with PKC peptides
#900Actriib-Fc polynucleotides, polypeptides, and compositions