ClassID:

108937

C12N9/22 - page 14 - CPC Classification

Classification description:

Enzymes; Proenzymes; Compositions thereof ; Processes for preparing, activating, inhibiting, separating or purifying enzymes; Hydrolases (3) acting on ester bonds (3.1) Ribonucleases RNAses, DNAses

Recent Application in this class:
#3901
20210344626
2021-11-04

RNA targeting methods and compositions

#3902
20210340598
2021-11-04

METHODS FOR ASSEMBLING DNA MOLECULES

#3903
20210340592
2021-11-04

Method for Determining Long Non-Coding Ribonucleic Acid Interaction Proteins

#3904
20210340575
2021-11-04

Methods and compositions for RNA-directed target DNA modification and for RNA-directed modulation of transcription

#3905
20210340574
2021-11-04

COMPOSITIONS AND METHODS FOR GENETIC MANIPULATION OF METHANOTROPHS

#3906
20210340571
2021-11-04

TARGETED GENOME MODIFICATION USING CIRCULAR SINGLE-STRANDED DNA

#3907
20210340568
2021-11-04

REGULATED GENE EDITING SYSTEM

#3908
20210340566
2021-11-04

Compositions and methods for differential Cas9 gene labeling and/or editing

#3909
20210340563
2021-11-04

DONOR T-CELLS WITH KILL SWITCH

#3910
20210340562
2021-11-04

ENGINEERED LONG INTERSPERSED ELEMENT (LINE) TRANSPOSONS AND METHODS OF USE

#3911
20210340554
2021-11-04

METHOD FOR PRODUCING GENOME-MODIFIED PLANTS FROM PLANT PROTOPLASTS AT HIGH EFFICIENCY

#3912
20210340532
2021-11-04

Thermostable Cas9 nucleases

#3913
20210340531
2021-11-04

Compositions and Methods for Inhibiting Intermediate Filament Tetramerization

#3914
20210340530
2021-11-04

Compositions and Methods for Immunotherapy

#3915
20210340528
2021-11-04

Method for modifying target nucleic acid in genome of cell

#3916
20210340513
2021-11-04

Engineered enzyme

#3917
20210340512
2021-11-04

Polypeptides Having DNase Activity

#3918
20210340508
2021-11-04

Genome Editing by Directed Non-Homologous DNA Insertion Using a Retroviral Integrase-Cas9 Fusion Protein

#3919
20210340496
2021-11-04

COMPOSITIONS AND METHODS FOR MODIFYING REGULATORY T CELLS

#3920
20210340199
2021-11-04

Modulators of CAS9 polypeptides and methods of use thereof

#3921
20210340197
2021-11-04

DIRECTED PSEUDOURIDYLATION OF RNA

#3922
20210337776
2021-11-04

Transgenic animals and transgenic embryos producing an engineered nuclease

#3923
20210332446
2021-10-28

ENGINEERED CRISPR-CAS SYSTEMS AND METHODS FOR SENSITIVE AND SPECIFIC DIAGNOSTICS

#3924
20210332429
2021-10-28

Methods, procedures and kits for providing maximum depth enrichment sequencing for identification for enrichment of rare genomic variants

#3925
20210332391
2021-10-28

Methods and compositions for RNA-directed target DNA modification and for RNA-directed modulation of transcription

#3926
20210332390
2021-10-28

Methods and compositions for RNA-directed target DNA modification and for RNA-directed modulation of transcription

#3927
20210332389
2021-10-28

Compositions, methods, modules and instruments for automated nucleic acid-guided nuclease editing in mammalian cells using microcarriers

#3928
20210332388
2021-10-28

COMPOSITIONS, METHODS, MODULES AND INSTRUMENTS FOR AUTOMATED NUCLEIC ACID-GUIDED NUCLEASE EDITING IN MAMMALIAN CELLS

#3929
20210332356
2021-10-28

NUCLEIC ACID CONSTRUCTS COMPRISING GENE EDITING MULTI-SITES AND USES THEREOF

#3930
20210332353
2021-10-28

Argonaute protein mutant and use thereof

#3931
20210332352
2021-10-28

Compositions, methods, modules and instruments for automated nucleic acid-guided nuclease editing in mammalian cells via viral delivery

#3932
20210332344
2021-10-28

DIRECTED MODIFICATION OF RNA

#3933
20210332339
2021-10-28

Nuclease domain and use thereof

#3934
20210332338
2021-10-28

FUSION MOLECULES OF RATIONALLY-DESIGNED DNA-BINDING PROTEINS AND EFFECTOR DOMAINS

#3935
20210332331
2021-10-28

Adeno-Associated-Virus Rep Sequences, Vectors and Viruses

#3936
20210332094
2021-10-28

NOVEL TRANSCRIPTION ACTIVATOR

#3937
20210330814
2021-10-28

Methods of treating non-syndromic sensorineural hearing loss

#3938
20210329926
2021-10-28

Effective disinfectant system for elimination of RNA viruses

#3939
20210325379
2021-10-21

Single-molecule electronic sequence detector and methods of use

#3940
20210324420
2021-10-21

METHOD FOR PRODUCING GENOME-EDITED CELL

#3941
20210324414
2021-10-21

COMPOSITIONS AND METHODS FOR SEQUESTERING VIRUSES

#3942
20210324406
2021-10-21

Methods and compositions for nucleic acid and protein payload delivery

#3943
20210324390
2021-10-21

METHODS FOR IMPROVING PRODUCTION OF BIOLOGICAL PRODUCTS BY REDUCING THE LEVEL OF ENDOGENOUS PROTEIN

#3944
20210324382
2021-10-21

Chimeric DNA:RNA Guide for High Accuracy Cas9 Genome Editing

#3945
20210324381
2021-10-21

THERAPEUTIC GENOME EDITING IN X-LINKED HYPER IGM SYNDROME

#3946
20210324358
2021-10-21

CRISPR-CAS EFFECTOR POLYPEPTIDES AND METHODS OF USE THEREOF

#3947
20210324357
2021-10-21

DEGRADATION DOMAIN MODIFICATIONS FOR SPATIO-TEMPORAL CONTROL OF RNA-GUIDED NUCLEASES

#3948
20210324356
2021-10-21

CRISPR-CAS EFFECTOR POLYPEPTIDES AND METHODS OF USE THEREOF

#3949
20210324355
2021-10-21

Mad nucleases

#3950
20210324340
2021-10-21

GENOMIC ENGINEERING OF PLURIPOTENT CELLS

#3951
20210324019
2021-10-21

DNA-BINDING PROTEIN USING PPR MOTIF, AND USE THEREOF

#3952
20210322525
2021-10-21

Sequence specific antimicrobials

#3953
20210322331
2021-10-21

NANOCAPSULES FOR THE DELIVERY OF CELL MODULATING AGENTS

#3954
20210317527
2021-10-14

REPORTER NUCLEIC ACIDS FOR TYPE V CRISPR-MEDIATED DETECTION

#3955
20210317479
2021-10-14

NUCLEIC ACID ASSEMBLIES FOR USE IN TARGETED DELIVERY

#3956
20210317448
2021-10-14

GENE EDITING OF ANTICOAGULANTS

#3957
20210317447
2021-10-14

CRISPR-Cas effector polypeptides and methods of use thereof

#3958
20210317446
2021-10-14

Advanced genome editing

#3959
20210317443
2021-10-14

Methods for screening for cancer targets

#3960
20210317440
2021-10-14

Adenosine nucleobase editors and uses thereof

#3961
20210317436
2021-10-14

METHODS AND COMPOSITIONS FOR MODIFYING THE VON WILLEBRAND FACTOR GENE

#3962
20210317435
2021-10-14

DOUBLE KNOCK-OUT CHO CELL LINE METHOD OF ITS GENERATION AND PRODUCING THERAPEUTIC PROTEINS THEREFROM

#3963
20210317430
2021-10-14

PROGRAMMED CELL DEATH 1 (PD1) SPECIFIC NUCLEASES

#3964
20210317429
2021-10-14

METHODS AND COMPOSITIONS FOR OPTOCHEMICAL CONTROL OF CRISPR-CAS9

#3965
20210317428
2021-10-14

Modified cells comprising CRISPR systems

#3966
20210317406
2021-10-14

GENE TARGETS FOR T-CELL-BASED IMMUNOTHERAPY

#3967
20210317168
2021-10-14

Complement Component 1s (C1s) Deficient Cells for Production of Vaccines and Biopharmaceutical Proteins

#3968
20210316014
2021-10-14

NUCLEIC ACID CONSTRUCTS AND METHODS OF USE

#3969
20210315994
2021-10-14

DELIVERY OF NEGATIVELY CHARGED PROTEINS USING CATIONIC LIPIDS

#3970
20210315950
2021-10-14

Elimination of colonic bacterial driving lethal inflammatory cardiomyopathy

#3971
20210315936
2021-10-14

Genetically engineered hematopoietic stem cells and uses thereof

#3972
20210310028
2021-10-07

METHODS AND COMPOSITIONS FOR RNA-DIRECTED TARGET DNA MODIFICATION AND FOR RNA-DIRECTED MODULATION OF TRANSCRIPTION

#3973
20210310012
2021-10-07

Curing for recursive nucleic acid-guided cell editing

#3974
20210309995
2021-10-07

HOMOLOGY-DIRECTED REPAIR TEMPLATE DESIGN AND DELIVERY TO EDIT HEMOGLOBIN-RELATED MUTATIONS

#3975
20210309986
2021-10-07

METHODS FOR EXON SKIPPING AND GENE KNOCKOUT USING BASE EDITORS

#3976
20210309981
2021-10-07

Variant type V CRISPR/Cas effector polypeptides and methods of use thereof

#3977
20210309980
2021-10-07

ENGINEERED CHIMERIC NUCLEIC ACID GUIDED NUCLEASE CONSTRUCTS AND USES THEREOF

#3978
20210309702
2021-10-07

Programmable Designer Therapeutic Fusogenic Secreted Gectosome Vesicles For Macromolecule Delivery And Genome Modification

#3979
20210309701
2021-10-07

Inducible, tunable, and multiplex human gene regulation using CRISPR-Cpf1

#3980
20210309691
2021-10-07

METHODS AND COMPOSITIONS FOR NUCLEOSIDE TRIPHOSPHATE AND RIBONUCLEIC ACID PRODUCTION

#3981
20210308183
2021-10-07

CHIMERIC ANTIGEN RECEPTOR T CELLS DERIVED FROM IMMUNOENGINEERED PLURIPOTENT STEM CELLS

#3982
20210308171
2021-10-07

METHODS FOR COMBINATORIAL SCREENING AND USE OF THERAPEUTIC TARGETS THEREOF

#3983
20210307303
2021-10-07

Method for preparing CKO/KI animal model by using CAS9 technology

#3984
20210301287
2021-09-30

Treatment Of Non-Alcoholic Fatty Liver Disease, Non-Alcoholic Steatohepatitis, And Liver Fibrosis

#3985
20210301283
2021-09-30

Methods for improving resistance to soybean rust

#3986
20210301282
2021-09-30

Methods for controlling meristem size for crop improvement

#3987
20210301274
2021-09-30

Compositions and Methods for Delivering a Nucleobase Editing System

#3988
20210301273
2021-09-30

Non-specific nucleases from the genus for use in facilitating flow of cells through a microfluidic channel

#3989
20210301272
2021-09-30

Nuclease-mediated nucleic acid modification

#3990
20210301271
2021-09-30

CRISPR-Cas effector polypeptides and methods of use thereof

#3991
20210301270
2021-09-30

Mad nucleases

#3992
20210301269
2021-09-30

RECOMBINANT CRISPR-CAS9 NUCLEASES WITH ALTERED PAM SPECIFICITY

#3993
20210301268
2021-09-30

NPP1 FUSION PROTEINS

#3994
20210301247
2021-09-30

SYSTEM FOR IMAGE-DRIVEN CELL MANUFACTURING

#3995
20210299178
2021-09-30

METHODS OF USING DNASE1-LIKE 3 IN THERAPY

#3996
20210299174
2021-09-30

CELL THERAPY

#3997
20210292824
2021-09-23

Crispr effector system based coronavirus diagnostics

#3998
20210292823
2021-09-23

Rapid diagnostics

#3999
20210292795
2021-09-23

Methods for increasing efficiency of nuclease-induced homology-directed repair

#4000
20210292794
2021-09-23

DELIVERY, ENGINEERING AND OPTIMIZATION OF TANDEM GUIDE SYSTEMS, METHODS AND COMPOSITIONS FOR SEQUENCE MANIPULATION

#4001
20210292784
2021-09-23

ENGINEERED INCOHERENT FEED FORWARD LOOP AND USES THEREOF

#4002
20210292777
2021-09-23

Method for Site-Specific Mutagenesis of Medicago Sativa Genes by Using CRISPR/Cas9 System

#4003
20210292775
2021-09-23

System and Methods for Engineering Bacteria Fit for Eukaryotic mRNA Production, Export, and Translation in a Eukaryotic Host

#4004
20210292774
2021-09-23

Iterative genome editing in microbes

#4005
20210292769
2021-09-23

Methods and compositions for directed genome editing

#4006
20210292754
2021-09-23

NATURAL GUIDE ARCHITECTURES AND METHODS OF MAKING AND USING THE SAME

#4007
20210292753
2021-09-23

Methods and compositions for directed genome editing

#4008
20210292749
2021-09-23

Method for fragmenting DNA by nick translation

#4009
20210292747
2021-09-23

ENGINEERED CHIMERIC NUCLEIC ACID GUIDED NUCLEASES COMPOSITIONS, METHODS FOR MAKING, AND SYSTEMS FOR GENE EDITING

#4010
20210292722
2021-09-23

NOVEL CRISPR-ASSOCIATED PROTEIN AND USE THEREOF

#4011
20210292721
2021-09-23

Type V CRISPR-Cas systems and use thereof

#4012
20210292429
2021-09-23

ANTI-LIV1 IMMUNE CELL CANCER THERAPY

#4013
20210290704
2021-09-23

TARGETED ELIMINATION OF BACTERIAL GENES

#4014
20210290677
2021-09-23

METHODS OF TREATING IMMUNOTHERAPY-RELATED TOXICITY USING A GM-CSF ANTAGONIST

#4015
20210285050
2021-09-16

PDE3B VARIANTS

#4016
20210285015
2021-09-16

THERAPEUTIC USES OF GENOME EDITING WITH CRISPR/Cas SYSTEMS

#4017
20210285010
2021-09-16

Compositions and methods for impeding transcription of expanded microsatellite repeats

#4018
20210284994
2021-09-16

Automated cell processing methods, modules, instruments, and systems

#4019
20210284993
2021-09-16

HTP genomic engineering platform for improving fungal strains

#4020
20210284981
2021-09-16

RNA-GUIDED NUCLEIC ACID MODIFYING ENZYMES AND METHODS OF USE THEREOF

#4021
20210284980
2021-09-16

RATIONALLY-DESIGNED MEGANUCLEASES WITH ALTERED SEQUENCE SPECIFICITY AND DNA-BINDING AFFINITY

#4022
20210284979
2021-09-16

METHODS AND COMPOSITIONS FOR GENETICALLY MANIPULATING GENES AND CELLS

#4023
20210284978
2021-09-16

Unconstrained genome targeting with near-PAMless engineered CRISPR-Cas9 variants

#4024
20210284709
2021-09-16

HPV-specific binding molecules

#4025
20210284697
2021-09-16

Methods and products for genetic engineering

#4026
20210277423
2021-09-09

THERAPEUTIC USES OF GENOME EDITING WITH CRISPR/Cas SYSTEMS

#4027
20210277422
2021-09-09

HOMOLOGY DEPENDENT REPAIR GENOME EDITING

#4028
20210277421
2021-09-09

Homologous Recombination Reporter Construct and Uses Thereof

#4029
20210277396
2021-09-09

Methods and compositions for sensitization of tumor cells to immune therapy

#4030
20210277392
2021-09-09

CHEMICALLY-MODIFIED GUIDE RNAS TO IMPROVE CRISPR-CAS PROTEIN SPECIFICITY

#4031
20210277391
2021-09-09

Treatment of ophthalmic conditions with angiopoietin-like 7 (ANGPTL7) inhibitors

#4032
20210277388
2021-09-09

Methods and compositions using one-sided transposition

#4033
20210277385
2021-09-09

METHOD FOR EDITING DNA IN CELL-FREE SYSTEM

#4034
20210277379
2021-09-09

MULTI-EFFECTOR NUCLEOBASE EDITORS AND METHODS OF USING SAME TO MODIFY A NUCLEIC ACID TARGET SEQUENCE

#4035
20210277373
2021-09-09

GENETICALLY-MODIFIED T CELLS COMPRISING A MODIFIED INTRON IN THE T CELL RECEPTOR ALPHA GENE

#4036
20210277372
2021-09-09

ENGINEERED DNASE ENZYMES AND USE IN THERAPY

#4037
20210277371
2021-09-09

ENGINEERING OF SYSTEMS, METHODS AND OPTIMIZED GUIDE COMPOSITIONS WITH NEW ARCHITECTURES FOR SEQUENCE MANIPULATION

#4038
20210277370
2021-09-09

COMPOSITIONS AND METHODS OF USE OF CRISPR-CAS SYSTEMS IN NUCLEOTIDE REPEAT DISORDERS

#4039
20210277120
2021-09-09

COMPOSITIONS AND METHODS FOR TREATMENT OF T CELL MALIGNANCIES

#4040
20210275584
2021-09-09

Immune cell compositions and methods of use for treating viral and other infections

#4041
20210274759
2021-09-09

A RODENT MODEL OF B4GALT1-MEDIATED FUNCTIONS

#4042
20210269866
2021-09-02

CRISPR EFFECTOR SYSTEM BASED AMPLIFICATION METHODS, SYSTEMS, AND DIAGNOSTICS

#4043
20210269831
2021-09-02

Delivery, Engineering and optimization of systems, methods and compositions for sequence manipulation and therapeutic applications

#4044
20210269801
2021-09-02

Methods of Managing Nucleic Acid Replication, Expression, and Cleavage Using CRISPR Associated Nucleases

#4045
20210269795
2021-09-02

Type VI-E and type VI-F CRISPR-Cas system and uses thereof

#4046
20210269790
2021-09-02

Virus-like particles and use thereof

#4047
20210269788
2021-09-02

Variants of Cpf1 (Cas12a) with altered PAM specificity

#4048
20210269785
2021-09-02

CRISPR-associated (Cas) protein

#4049
20210269784
2021-09-02

Simultaneous multiplex genome editing in yeast

#4050
20210269783
2021-09-02

Haplotype-based treatment of RP1 associated retinal degenerations

#4051
20210269782
2021-09-02

RNA-GUIDED EFFECTOR PROTEINS AND METHODS OF USE THEREOF

#4052
20210268015
2021-09-02

Sideroflexins as mitochondrial serine transporters

#4053
20210267976
2021-09-02

Pharmaceutical composition for topical wound treatment

#4054
20210262025
2021-08-26

MULTIPLEXED IN VIVO DISEASE SENSING WITH NUCLEIC ACID-BARCODED REPORTERS

#4055
20210261982
2021-08-26

RAAV-MEDIATED NUCLEASE-ASSOCIATED VECTOR INTEGRATION (RAAV-NAVI)

#4056
20210261977
2021-08-26

METHOD FOR IMPROVING RICE YIELD BY JOINTLY KNOCKING OUT ABA RECEPTOR PYL FAMILY GENES AND USE THEREOF

#4057
20210261974
2021-08-26

Methods and compositions for increasing efficiency of targeted gene modification using oligonucleotide-mediated gene repair

#4058
20210261962
2021-08-26

CORRECTION OF DYSTROPHIN EXON 43, EXON 45, OR EXON 52 DELETIONS IN DUCHENNE MUSCULAR DYSTROPHY

#4059
20210261960
2021-08-26

METHOD OF USING CUT&RUN OR CUT&TAG TO VALIDATE CRISPR-CAS TARGETING

#4060
20210261957
2021-08-26

VESICLES FOR TRACELESS DELIVERY OF GUIDE RNA MOLECULES AND/OR GUIDE RNA MOLECULE/RNA-GUIDED NUCLEASE COMPLEX(ES) AND A PRODUCTION METHOD THEREOF

#4061
20210261956
2021-08-26

Gene editing to improve joint function

#4062
20210261955
2021-08-26

Compositions and methods for treating hemoglobinopathies

#4063
20210261946
2021-08-26

Coupling endonucleases with end-processing enzymes drives high efficiency gene disruption

#4064
20210261938
2021-08-26

Evolution of cytidine deaminases

#4065
20210261932
2021-08-26

CRISPR-Cas enzymes with enhanced on-target activity

#4066
20210261930
2021-08-26

Delivery of CAS9 via ARRDC1-mediated microvesicles (ARMMs)

#4067
20210261919
2021-08-26

Methods and compositions for treating cancer

#4068
20210260170
2021-08-26

Method of treating diseases associated with MYD88 pathways using CRISPR-GNDM system

#4069
20210260130
2021-08-26

COMPOSITIONS AND METHODS FOR INHIBITION OF LINEAGE SPECIFIC ANTIGENS

#4070
20210260117
2021-08-26

Modified cells and methods of therapy

#4071
20210259980
2021-08-26

Compositions and methods for organ specific delivery of nucleic acids

#4072
20210259218
2021-08-26

Methods of genetic mediated engineering of RNAi models

#4073
20210254127
2021-08-19

Nuclease profiling system

#4074
20210254104
2021-08-19

CRISPR enabled multiplexed genome engineering

#4075
20210254099
2021-08-19

Methods for scarless introduction of targeted modifications into targeting vectors

#4076
20210254086
2021-08-19

Composition for editing flavonoid biosynthetic gene by using CRISPR/Cas9 system, and use thereof

#4077
20210254068
2021-08-19

GENOME ENGINEERING PRIMARY MONOCYTES

#4078
20210254057
2021-08-19

Compositions and methods for gene editing by targeting transferrin

#4079
20210254054
2021-08-19

Artificially-manipulated neovascularization regulatory system

#4080
20210254043
2021-08-19

Coupling endonucleases with end-processing enzymes drives high efficiency gene disruption

#4081
20210254042
2021-08-19

Synthetic RNA binding polypeptides

#4082
20210254038
2021-08-19

CRISPR-CAS EFFECTOR POLYPEPTIDES AND METHODS OF USE THEREOF

#4083
20210253982
2021-08-19

Use of Polypeptide

#4084
20210253673
2021-08-19

COMPOSITIONS AND METHODS FOR INHIBITING ENDOGENOUS IMMUNOGLOBULIN GENES AND PRODUCING TRANSGENIC HUMAN IDIOTYPE ANTIBODIES

#4085
20210252118
2021-08-19

Compositions and methods for treating hemoglobinopathies

#4086
20210252114
2021-08-19

METHODS AND COMPOSITIONS FOR RNA-GUIDED TREATMENT OF HIV INFECTION

#4087
20210252082
2021-08-19

Gene editing to improve joint function

#4088
20210252060
2021-08-19

Materials and methods for engineering cells and uses thereof in immuno-oncology

#4089
20210246574
2021-08-12

Nucleic acid-guided editing of exogenous polynucleotides in heterologous cells

#4090
20210246473
2021-08-12

MODIFIED CAS9 PROTEIN, AND USE THEREOF

#4091
20210246472
2021-08-12

DOWN-REGULATION OF THE CYTOSOLIC DNA SENSOR PATHWAY

#4092
20210246471
2021-08-12

MODIFICATION OF HEAVY CHAIN FIBROIN IN BOMBYX MORI

#4093
20210246470
2021-08-12

COMPLEX FOR THE DELIVERY OF CAS9 PROTEINS AND GUIDE RNA TO CELLS

#4094
20210246466
2021-08-12

REGULATABLE GENE EDITING COMPOSITIONS AND METHODS

#4095
20210246436
2021-08-12

Electrochemical biosensor

#4096
20210246425
2021-08-12

Methods and compositions for treating cancer

#4097
20210238628
2021-08-05

ENGINEERED CELLS WITH MODIFIED HOST CELL PROTEIN PROFILES

#4098
20210238618
2021-08-05

COMPOSITIONS AND METHODS FOR REDUCING CAFFEINE CONTENT IN COFFEE BEANS

#4099
20210238614
2021-08-05

METHODS AND COMPOSITIONS FOR HOMOLOGY DIRECTED REPAIR OF DOUBLE STRAND BREAKS IN PLANT CELL GENOMES

#4100
20210238612
2021-08-05

TYPE V CRISPR/NUCLEASE-SYSTEM FOR GENOME EDITING IN PLANT CELLS

#4101
20210238598
2021-08-05

COMPOSITIONS, SYSTEMS, AND METHODS FOR BASE DIVERSIFICATION

#4102
20210238568
2021-08-05

Chimeric antigen receptor (CAR) and T cell receptor (TCR) modified T cells

#4103
20210238567
2021-08-05

CRISPR-Cas effector polypeptides and methods of use thereof

#4104
20210238566
2021-08-05

High fidelity restriction endonucleases

#4105
20210238535
2021-08-05

AUTOMATED PRODUCTION OF CAR-EXPRESSING CELLS

#4106
20210238257
2021-08-05

De Novo Formation of the Biliary System by Hepatocyte Transdifferentiation

#4107
20210238222
2021-08-05

PRODUCING RECOMBINANT PROTEINS WITH REDUCED LEVELS OF HOST CELL PROTEINS

#4108
20210236559
2021-08-05

Genetically engineered hematopoietic stem cells and uses thereof

#4109
20210236551
2021-08-05

Materials and methods for engineering cells and uses thereof in immuno-oncology

#4110
20210236534
2021-08-05

Compositions and methods for the treatment of expanded repeat-associated disorders

#4111
20210230690
2021-07-29

BIOSENSOR

#4112
20210230664
2021-07-29

LABELING OF DNA

#4113
20210230639
2021-07-29

Methods and compositions for RNA-directed target DNA modification and for RNA-directed modulation of transcription

#4114
20210230638
2021-07-29

SYSTEMS AND METHODS FOR THE TREATMENT OF HEMOGLOBINOPATHIES

#4115
20210230636
2021-07-29

NUCLEIC ACID DELIVERY CARRIER, NUCLEIC ACID DELIVERY CARRIER SET, NUCLEIC ACID DELIVERY COMPOSITION, AND NUCLEIC ACID DELIVERY METHOD

#4116
20210230631
2021-07-29

GENE THERAPY FOR CNS DEGENERATION

#4117
20210230615
2021-07-29

Gene Targeting

#4118
20210230588
2021-07-29

Methods and systems of molecular recording by CRISPR-Cas system

#4119
20210230581
2021-07-29

High fidelity restriction endonucleases

#4120
20210230577
2021-07-29

Cytosine to guanine base editor

#4121
20210230568
2021-07-29

MICROHOMOLOGY MEDIATED REPAIR OF MICRODUPLICATION GENE MUTATIONS

#4122
20210230567
2021-07-29

Mutant CPF1 endonucleases

#4123
20210230517
2021-07-29

Use of Polypeptide

#4124
20210228693
2021-07-29

PRECISE DELETION OF CHROMOSOMAL SEQUENCES IN VIVO AND TREATMENT OF NUCLEOTIDE REPEAT EXPANSION DISORDERS USING ENGINEERED NUCLEASES

#4125
20210228641
2021-07-29

Genetically engineered hematopoietic stem cells and uses thereof

#4126
20210228631
2021-07-29

Targeted replacement of endogenous T cell receptors

#4127
20210228630
2021-07-29

GENERATION OF KNOCK-OUT PRIMARY AND EXPANDED HUMAN NK CELLS USING CAS9 RIBONUCLEOPROTEINS

#4128
20210222205
2021-07-22

Methods and compositions for RNA-directed target DNA modification and for RNA-directed modulation of transcription

#4129
20210222204
2021-07-22

CATALYTICALLY INACTIVE TRUNCATED GUIDE RNA COMPOSITIONS AND RELATED METHODS FOR SUPPRESSION OF CRISPR/CAS OFF-TARGET EDITING

#4130
20210222193
2021-07-22

RNA-Guided Human Genome Engineering

#4131
20210222173
2021-07-22

Compositions and Methods for Lactate Dehydrogenase (LDHA) Gene Editing

#4132
20210222171
2021-07-22

CRISPR/CAS9 SYSTEMS, AND METHODS OF USE THEREOF

#4133
20210222164
2021-07-22

CRISPR-CAS SYSTEMS HAVING DESTABILIZATION DOMAIN

#4134
20210222159
2021-07-22

AUTOMATED CELL PROCESSING METHODS, MODULES, INSTRUMENTS, AND SYSTEMS

#4135
20210222151
2021-07-22

TARGETED TREATMENT OF LEBER CONGENITAL AMOUROSIS

#4136
20210222150
2021-07-22

GENE-DRIVE IN DNA VIRUSES

#4137
20210222140
2021-07-22

Compositions and methods for genome engineering with Cas12a proteins

#4138
20210222139
2021-07-22

Single adeno-associated virus (AAV)-sized nucleotide for use in CRISPR interference or activation

#4139
20210221861
2021-07-22

INDUCTION OF DNA STRAND BREAKS AT CHROMATIN TARGETS

#4140
20210220407
2021-07-22

Genetically engineered hematopoietic stem cells and uses thereof

#4141
20210214752
2021-07-15

NON-DISRUPTIVE GENE TARGETING

#4142
20210214724
2021-07-15

Nucleic acid modifiers

#4143
20210214723
2021-07-15

MATERIALS AND METHODS FOR TREATING CANCER

#4144
20210214714
2021-07-15

CBLB endonuclease variants, compositions, and methods of use

#4145
20210214700
2021-07-15

CBLB endonuclease variants, compositions, and methods of use

#4146
20210214699
2021-07-15

METHODS AND COMPOSITIONS FOR MODULATING MYELOPEROXIDASE (MPO) EXPRESSION

#4147
20210214698
2021-07-15

CAS9 VARIANTS AND USES THEREOF

#4148
20210214697
2021-07-15

Class 2 CRISPR/Cas compositions and methods of use

#4149
20210213062
2021-07-15

Drug-Resistant Immune Cells and Methods of Use Thereof

#4150
20210207203
2021-07-08

CRISPR DOUBLE NICKASE BASED AMPLIFICATION COMPOSITIONS, SYSTEMS, AND METHODS

#4151
20210207175
2021-07-08

COMPOUND FOR REGULATING GENE EDITING EFFICIENCY AND APPLICATION THEREOF

#4152
20210207173
2021-07-08

CRISPR-BASED GENOME MODIFICATION AND REGULATION

#4153
20210207169
2021-07-08

VIRAL DELIVERY OF RNA UTILIZING SELF-CLEAVING RIBOZYMES AND CRISPR-BASED APPLICATIONS THEREOF

#4154
20210207165
2021-07-08

CRISPR-BASED GENOME MODIFICATION AND REGULATION

#4155
20210207139
2021-07-08

Programmable and portable CRISPR-Cas transcriptional activation in bacteria

#4156
20210207134
2021-07-08

RECONSTITUTION OF DNA-END REPAIR PATHWAY IN PROKARYOTES

#4157
20210207133
2021-07-08

Reverse transcriptases and uses thereof

#4158
20210207130
2021-07-08

METHODS AND COMPOSITIONS FOR THE MAKING AND USING OF GUIDE NUCLEIC ACIDS

#4159
20210207119
2021-07-08

Compositions and methods for promoting homology directed repair mediated gene editing

#4160
20210207114
2021-07-08

Engineering of DNASE enzymes for manufacturing and therapy

#4161
20210205436
2021-07-08

Immunogenic composition comprising a recombinant attenuated mopeia virus with a modified nucleoprotein displaying reduced exonuclease activity

#4162
20210202034
2021-07-01

Method for detecting on-target and predicted off-target genome editing events

#4163
20210198699
2021-07-01

KIT FOR REPARING FBN1T7498C MUTATION, COMBINATION FOR MAKING AND REPAIRING MUTATION, AND METHOD OF REPAIRING THEREOF

#4164
20210198696
2021-07-01

Gene editing method using virus

#4165
20210198670
2021-07-01

Method for knocking out N-myristoyltransferase (NMT) gene from

#4166
20210198664
2021-07-01

NOVEL CRISPR-ASSOCIATED SYSTEMS AND COMPONENTS

#4167
20210198660
2021-07-01

COMPOSITIONS AND METHODS FOR MAKING GUIDE NUCLEIC ACIDS

#4168
20210198642
2021-07-01

COMPOSITIONS AND METHODS FOR IMPROVED NUCLEASES

#4169
20210198641
2021-07-01

MAD nucleases

#4170
20210198330
2021-07-01

Base editors and uses thereof

#4171
20210198328
2021-07-01

MODULATED CAS-INHIBITORS

#4172
20210189485
2021-06-24

SEQUENCE DETECTION SYSTEMS

#4173
20210189459
2021-06-24

Compositions and methods for targeted depletion, enrichment, and partitioning of nucleic acids using CRISPR/Cas system proteins

#4174
20210189435
2021-06-24

System for DNA editing and uses thereof

#4175
20210189426
2021-06-24

CRISPR INTERFERENCE BASED HTT ALLELIC SUPPRESSION AND TREATMENT OF HUNTINGTON DISEASE

#4176
20210189416
2021-06-24

Creation of herbicide resistant gene and use thereof

#4177
20210189406
2021-06-24

Single-vector type I vectors

#4178
20210189405
2021-06-24

Methods and compositions for regulation of transgene expression

#4179
20210189404
2021-06-24

METHOD FOR PRODUCING FUSION PROTEIN, NUCLEIC ACID, CELL, AND ANIMAL

#4180
20210189388
2021-06-24

DNA-guided gene editing and regulation

#4181
20210189387
2021-06-24

GENE EDITING SYSTEM OF PSEUDOMONAS PUTIDA AND GENE EDITING METHOD THEREOF

#4182
20210189386
2021-06-24

NUCLEIC ACID CONSTRUCT, MEDICINAL COMPOSITION, ANTICANCER AGENT, ANTIVIRAL AGENT AND ANTIBACTERIAL AGENT

#4183
20210189375
2021-06-24

Method for regulating gene expression

#4184
20210189362
2021-06-24

Detergent composition comprising a DNase

#4185
20210189361
2021-06-24

DOWNREGULATION OF SNCA EXPRESSION BY TARGETED EDITING OF DNA-METHYLATION

#4186
20210188926
2021-06-24

METHODS AND COMPOSITIONS FOR GENOME ENGINEERING

#4187
20210187040
2021-06-24

IPSC-DERIVED SECRETOME COMPOSITIONS, AND RELATED SYSTEMS AND METHODS

#4188
20210187006
2021-06-24

TALEN-BASED GENE CORRECTION

#4189
20210180090
2021-06-17

Nucleic acid-guided nucleases

#4190
20210180087
2021-06-17

IN SITU GENE EDITING

#4191
20210180076
2021-06-17

Compositions and methods for genome editing in plants

#4192
20210180074
2021-06-17

Abiotic stress tolerant plants and polynucleotides to improve abiotic stress and methods

#4193
20210180071
2021-06-17

GENOME EDITING IN BACTEROIDES

#4194
20210180059
2021-06-17

COMPOSITIONS AND METHODS FOR IMPROVING THE EFFICACY OF CAS9-BASED KNOCK-IN STRATEGIES

#4195
20210180055
2021-06-17

Systems and methods for gene modification

#4196
20210180053
2021-06-17

SYNTHETIC RNAS AND METHODS OF USE

#4197
20210180047
2021-06-17

Automated cell processing methods, modules, instruments, and systems

#4198
20210180045
2021-06-17

SCALABLE TAGGING OF ENDOGENOUS GENES BY HOMOLOGY-INDEPENDENT INTRON TARGETING

#4199
20210180038
2021-06-17

Engineered meganucleases specific for recognition sequences in the Hepatitis B virus genome

#4200
20210180017
2021-06-17

Enhanced immune effector cells and use thereof