COMPOSITIONS AND METHODS FOR TREATING OR PREVENTING AUTOIMMUNE DISEASES

COMPOSITIONS AND METHODS FOR PREPARING CAPPED CIRCULAR RNA MOLECULES

RECOMBINANT PRODUCTION OF PSILOCIN AND RELATED COMPOUNDS

METHOD FOR PRODUCING CELL HAVING DNA DELETION SPECIFIC TO ONE OF HOMOLOGOUS CHROMOSOMES

TEMPERATURE REGULATED CRISPR-CAS SYSTEMS AND METHODS OF USE THEREOF

METHODS FOR GENOME EDITING

GENE-EDITING METHODS FOR EMBRYONIC STEM CELLS

LETTUCE WITH INCREASED SHELF LIFE

COMPOSITIONS, SYSTEMS, AND METHODS FOR REGULATION OF HEPATITIS B VIRUS THROUGH TARGETED GENE REPRESSION

METHODS AND COMPOSITIONS FOR TARGETED GENOMIC INSERTION

CRISPR/CAS SCREENING PLATFORM TO IDENTIFY GENETIC MODIFIERS OF TAU SEEDING OR AGGREGATION

PROGRAMMABLE NUCLEASE-PEPTIDASE COMPOSITIONS

NUCLEASE HAVING IMPROVED SALT TOLERANCE AND/OR TEMPERATURE PERFORMANCE

NUCLEIC ACID MOLECULES ENCODING NUCLEASE-ALBUMIN FUSION PROTEINS

CIRCULAR PERMUTANTS, COMPOSITIONS COMPRISING THE SAME, AND METHODS OF USE THEREOF

ENGINEERED HUMAN EXTRACELLULAR DNASE ENZYMES

ENGINEERING CELLS FOR CELL-BASED THERAPIES, AND ASSOCIATED COMPOSITIONS AND METHODS

SCAFFOLDS FOR MODIFYING IMMUNE CELLS AND THE USES THEREOF

TARGETED INTEGRATION AT BETA-GLOBIN LOCUS IN HUMAN HEMATOPOIETIC STEM AND PROGENITOR CELLS

GENE EDITING SYSTEMS COMPRISING AN RNA GUIDE TARGETING STATHMIN 2 (STMN2) AND USES THEREOF

PH-RESPONSIVE NANO PARTICLE FOR DELIVERY OF RIBONUCLEOPROTEINS

MODIFIED TUMOR INFILTRATING LYMPHOCYTE AND USE THEREOF

GENETICALLY MODIFIED CELLS FOR ALLOGENEIC CELL THERAPY TO REDUCE INSTANT BLOOD MEDIATED INFLAMMATORY REACTIONS

COMPOSITIONS AND METHODS FOR ENGINEERING STABLE TREGS

MODULATION OF TGF BETA SIGNALING IN GENETICALLY-MODIFIED EUKARYOTIC CELLS

COMPOSITIONS AND METHODS FOR THE TREATMENT OF HEMOGLOBINOPATHIES

Methods and Compositions for RNA-Directed Target DNA Modification and for RNA-Directed Modulation of Transcription

NOVEL CAS9 ORTHOLOGS

CRISPR-ASSOCIATED TRANSPOSASES AND METHODS OF USE THEREOF

COMPOSITIONS AND METHODS FOR GENE MODIFICATION

POLYCISTRONIC VECTORS FOR CELL-BASED THERAPIES

METHODS AND COMPOSITIONS FOR IMPROVING CROP YIELD TRAITS

Method for Activating Expression of Silenced Glu-1Ax-null Subunit in Wheat and Related Biomaterials

GENERATION OF SITE SPECIFIC INTEGRATION SITES FOR COMPLEX TRAIT LOCI IN CORN AND SOYBEAN, AND METHODS OF USE

CLEAVE AND RESCUE GAMETE KILLERS FOR GENE DRIVE IN PLANTS

Compositions for Inducing Modifications of Target Endogenous Nucleic Acid Sequences in Nucleuses of Eukaryotic Cells

CIRCULAR RNAS AND PREPARATION METHODS THEREOF

MATERIALS AND METHODS FOR TREATMENT OF USHER SYNDROME TYPE 2A AND/OR NON-SYNDROMIC AUTOSOMAL RECESSIVE RETINITIS PIGMENTOSA (ARRP)

OPTIMIZED PROTEIN FUSIONS AND LINKERS

Nucleic Acid-Guided Nucleases

Protein Thermostability Reduction by Tag Fusion and Its Usage

HEMOSTATIC COMPOSITION CONTAINING RECOMBINANT HUMAN CLOTTING FACTORS, AND METHOD OF PRODUCING

TREATMENT OF RETINITIS PIGMENTOSA USING ENGINEERED MEGANUCLEASES

ENHANCED NUCLEIC ACID DETECTION USING CAS13 AND DESIGNED SECONDARY STRUCTURE

PROGRAMMABLE NUCLEASE-BASED ASSAY IMPROVEMENTS

ENGINEERED MULTIPARTITE TRANSCRIPTIONAL EFFECTORS SOURCED FROM HUMAN PROTEIN DOMAINS

SYSTEM AND METHOD FOR EDITING GENOMIC DNA TO MODULATE SPLICING

GENOME EDITING WITH CRISPR/CAS NUCLEASES COMPRISING COLLATERAL ACTIVITY

SYSTEMS AND METHODS FOR CELLULAR REPROGRAMMING OF A PLANT CELL

Treatment Of Uveitis With Endoplasmic Reticulum Aminopeptidase 1 (ERAP1) Inhibitors

SCHWANN CELL-SPECIFIC PROMOTER

COMPOSITIONS AND METHODS FOR EDITING GENOMES

METHODS AND COMPOSITIONS FOR PRIME EDITING NUCLEOTIDE SEQUENCES

HAPLOTYPE-BASED TREATMENT OF RP1 ASSOCIATED RETINAL DEGENERATIONS

MODIFIED VERO CELLS AND METHODS OF USING THE SAME FOR VIRUS PRODUCTION

VIRAL VECTOR PRODUCTION SYSTEM

GENERATION OF INDUCED PLURIPOTENT CELLS BY CRISPR ACTIVATION

COMPOSITIONS AND METHODS FOR CELL ENGINEERING FOR MEAT PRODUCTION

Gene Editing and Delivery of Myeloid Cells To Promote Wound Healing

THERAPEUTIC APPLICATIONS OF CPF1-BASED GENOME EDITING

METHODS FOR ENHANCING THERAPEUTIC EFFICACY OF ISOLATED CELLS FOR CELL THERAPY

CRYOGENICALLY ARRAYABLE STABLE TRANSFECTION

GENETICALLY MODIFIED MOUSE MODELS AND METHODS OF USE THEREOF

CRISPR-CAS-BASED COMPOSITION FOR SALMONELLA DETECTION AND SALMONELLA DETECTION METHOD USING SAME

COMPOSITIONS AND METHODS FOR TARGETED DEPLETION, ENRICHMENT, AND PARTITIONING OF NUCLEIC ACIDS USING CRISPR/CAS SYSTEM PROTEINS

Method for Producing Genetically Modified Cells

COMPOSITIONS AND METHODS FOR IMMUNOONCOLOGY

SIGNAL BOOST CASCADE ASSAY

S. PYOGENES CAS9 MUTANT GENES AND POLYPEPTIDES ENCODED BY SAME

FUSION PROTEINS, COMPOSITIONS COMPRISING THE SAME, AND METHODS OF USE THEREOF

REDUCTION OF RESIDUAL DNA IN MICROBIAL FERMENTATION PRODUCTS

COMPOSITIONS AND METHODS FOR REDUCING COMPLEMENT ACTIVATION

TRIGGER NUCLEIC ACIDS AND RNA-BINDING PROTEINS FOR UPREGULATING GENE EXPRESSION

Exon skipping to treat Usher Syndrome

CRISPR-MEDIATED HUMAN GENOME EDITING WITH VECTORS

METHODS OF SUBSTITUTING PATHOGENIC AMINO ACIDS USING PROGRAMMABLE BASE EDITOR SYSTEMS

Improved Probiotic Potency of the Yeast Saccharomyces Boulardii

COMPOSITIONS AND METHODS FOR TREATMENT OF ANEUPLOID CANCERS

AMPLIFICATION ASSAYS USING CRISPR-CAS BASED DETECTION

EFFECTOR PROTEINS, COMPOSITIONS, SYSTEMS, DEVICES, KITS AND METHODS OF USE THEREOF

Thermostable RNA Polymerase

BASE EDITOR AND THE USE THEREOF

DELIVERY AND USE OF THE CRISPR-CAS SYSTEMS, VECTORS AND COMPOSITIONS FOR HEPATIC TARGETING AND THERAPY

PREPARATION TECHNIQUE FOR UNIVERSAL CAR-T CELL, AND USE OF UNIVERSAL CAR-T CELL THEREOF

METHOD OF EDITING NUCLEIC ACID

Nuclease-Independent Targeted Gene Editing Platform and Uses Thereof

Controllable Transcription

Method for Improving Wheat Resistance To Fusarium Head Blight (FHB) By Genome Editing

MATERIALS AND METHODS FOR CONTROLLING GENE EDITING

COMPOSITIONS AND METHODS TO TREAT CANCER

NANOPARTICLES FUNCTIONALIZED WITH GENE EDITING TOOLS AND RELATED METHODS

COMPOSITIONS AND METHODS FOR TREATMENT OF TRANSTHYRETIN AMYLOIDOSIS

NOVEL CRISPR ENZYMES AND SYSTEMS

EVOLVED CAS14A1 VARIANTS, COMPOSITIONS, AND METHODS OF MAKING AND USING SAME IN GENOME EDITING

NOVEL CRISPR-CAS12I SYSTEMS AND USES THEREOF

RNA TARGETING METHODS AND COMPOSITIONS

GENE EDITING TO IMPROVE PANCREATIC BETA CELL YIELD IN DIRECTED DIFFERENTIATION OF HUMAN PLURIPOTENT STEM CELLS

GENETICALLY MODIFIED CELLS AND COMPOSITIONS AND USES THEREOF

METHODS AND COMPOSITIONS FOR THE TREATMENT OF RARE DISEASES

COMPOSITIONS AND METHODS FOR ENHANCING INTRA-MITOCHONDRIAL PROTEIN TRANSLATION AND OXIDATIVE PHOSPHORYLATION

Compositions And Methods For Regulating ZNF865

USE OF TCR-DEFICIENT CAR-TREGS IN COMBINATION WITH ANTI-TCR COMPLEX MONOCLONAL ANTIBODIES FOR INDUCING DURABLE TOLERANCE

METHODS OF AND COMPOSITIONS FOR REDUCING GENE EXPRESSION AND/OR ACTIVITY

EXTRACELLULAR VESICLES

IONIZABLE LIPIDS, LIPID NANOPARTICLES, AND USES THEREOF

COMPOSITIONS AND METHODS FOR DELIVERY OF NUCLEIC ACIDS

NANOZYME-CATALYSED DETECTION OF NUCLEIC ACIDS

IDENTIFICATION OF NANOPARTICLES FOR PREFERENTIAL TISSUE OR CELL TARGETING

CAS ENDONUCLEASES AND RELATED METHODS

FgTad2-FgTad3-Ame1 EDITING ENZYME SYSTEM, EDITING TOOL, AND EDITING METHOD

GENE THERAPY TARGETING THE NEONATAL FORM OF NAV1.5 FOR TREATING CANCER

POLYPEPTIDES USEFUL FOR GENE EDITING AND METHODS OF USE

PROMOTERS FOR VIRAL-BASED GENE THERAPY

SYSTEMS, METHODS, AND COMPOSITIONS FOR SITE-SPECIFIC GENETIC ENGINEERING USING PROGRAMMABLE ADDITION VIA SITE-SPECIFIC TARGETING ELEMENTS (PASTE)

GUIDE RNA WITH CHEMICAL MODIFICATIONS

ADENOSINE NUCLEOBASE EDITORS AND USES THEREOF

RNA-GUIDED NUCLEASES AND DNA BINDING PROTEINS

CRISPR GENE THERAPY OF FUSION GENE RELATED CANCERS

CAS ENDONUCLEASES AND RELATED METHODS

EVOLVED CAS9 PROTEINS FOR GENE EDITING

CRISPR-MEDIATED DELETION OF FLI1 IN NK CELLS

NUCLEASE HAVING IMPROVED SALT TOLERANCE AND/OR TEMPERATURE PERFORMANCE

COMPOSITIONS FOR INCREASING POLYPEPTIDE STABILITY AND ACTIVITY, AND RELATED METHODS

ANTIBODY-EVADING VIRUS VECTORS

METHODS AND SYSTEMS FOR CORRECTING MUTATIONS IN PRPH2

MITOCHONDRIAL BASE EDITORS AND METHODS FOR EDITING MITOCHONDRIAL DNA

Precise Excisions of Portions of Exon 44, 50, and 53 for Treatment of Duchenne Muscular Dystrophy

MODIFIED REGULATORY T CELLS AND METHODS OF USING THE SAME

TREATMENT OF AUTOIMMUNE DISEASES WITH ENGINEERED IMMUNE CELLS

GENETICALLY ENGINEERED CELLS HAVING ANTI-CD133 / ANTI-EGFR CHIMERIC ANTIGEN RECEPTORS, AND USES THEREOF

LIPID NANOPARTICLE COMPOSITIONS

METHODS OF BIALLELIC MODIFICATION

RECOMBINANT LENTIVIRAL VECTOR FOR STEM CELL-BASED GENE THERAPY OF SICKLE CELL DISORDER

LODGING RESISTANCE IN ERAGROSTIS TEF

METHODS AND COMPOSITIONS TO REGULATE MAPT SPLICING FOR MODELING AND TREATMENT OF TAUOPATHIES

COMPOSITIONS AND METHODS FOR CAPPING RNAS

COMPOSITIONS AND METHODS FOR EFFICIENT IN VIVO DELIVERY

COMPOSITIONS AND METHODS FOR EFFICIENT IN VIVO DELIVERY

SYSTEMS FOR MODULATING DRUG METABOLISM BY CELLS, METHODS AND COMPOSITIONS THEREOF

METHODS OF PURIFYING DNA FOR GENE SYNTHESIS

NUCLEIC ACID MOLECULES ENCODING DNA MODIFYING ENZYMES AND ACTIVE FRAGMENTS AND VARIANTS THEREOF AND COMPOSITIONS COMPRISING THE SAME

STRATEGIES FOR DIRECT RECRUITMENT OF REPAIR TEMPLATES TO CRISPR NUCLEASES

NOVEL SMALL TYPE V RNA PROGRAMMABLE ENDONUCLEASE SYSTEMS

COMPOSITIONS FOR MODULATING EXPRESSION OF SODIUM VOLTAGE-GATED CHANNEL ALPHA SUBUNIT 1 AND USES THEREOF

RNA GUIDED ERADICATION OF HUMAN JC VIRUS AND OTHER POLYOMAVIRUSES

COMPOUNDS, TARGETS, AND METHODS FOR MODULATING LYTIC GRANULE CONVERGENCE IN CYTOTOXIC CELLS TO PROMOTE BYSTANDER KILLING IN CELLULAR THERAPIES

PRECISE DELETION OF CHROMOSOMAL SEQUENCES IN VIVO AND TREATMENT OF NUCLEOTIDE REPEAT EXPANSION DISORDERS USING ENGINEERED NUCLEASES

SYSTEMS OF ENGINEERED RECEPTORS TARGETING PSMA AND CA9

CRISPR EFFECTOR SYSTEM BASED DIAGNOSTICS

COMPOSITIONS AND METHODS FOR BASE EDITING KINASE GENES

MULTIPLEX EDITING WITH CAS ENZYMES

NUCLEIC ACID-GUIDED NUCLEASES

METHODS OF EDITING NUCLEIC ACID SEQUENCES

COMPOSITIONS AND METHODS FOR GENOME EDITING ACROSS GRAFT-JUNCTIONS

TISSUE SPECIFIC METHODS AND COMPOSITIONS FOR GENE EDITING

COMPOSITIONS AND METHODS FOR TARGETED MODIFICATION OF MSH3

MOLECULAR RECORDING METHODS AND SYSTEMS TO CAPTURE LINEAGE RELATIONSHIPS IN DIFFERENTIATING STEM CELLS

ENGINEERED DEAMINASES

SYNTHETIC TRANSCRIPTION FACTORS

GENOME EDITING COMPOSITIONS AND METHODS FOR TREATMENT OF FRAGILE X SYNDROME

COMPOSITIONS AND METHODS FOR DELIVERING CARGO TO A TARGET CELL

DETECTION OF GENETIC VARIANTS OF THE BETA-ADRENERGIC RECEPTOR PATHWAY FOR DETECTING AND TREATING RETINOPATHY OF PREMATURITY

SPLIT-LUCIFERASE REPORTER SYSTEMS, COLOR-CODED BEAD MULTIPLEX CRISPR SYSTEMS, AND METHODS OF USE THEREOF IN CRISPR-CAS BASED DIAGNOSTICS

A METHOD FOR GENETIC MODIFICATION FOR HIGH GC CONTENT MICROORGANISMS

CRISPR-ASSOCIATED TRANSPOSONS AND USES THEREOF

NUCLEIC ACID-GUIDED NUCLEASES

ELECTROPORATION ENHANCERS FOR CRISPR-CAS SYSTEMS

COMPOSITIONS AND METHODS COMPRISING PLANTS WITH MODIFIED SUGAR CONTENT

METHODS AND COMPOSITIONS FOR INCREASING EFFICIENCY OF TARGETED GENE MODIFICATION USING OLIGONUCLEOTIDE-MEDIATED GENE REPAIR

USE OF TAWOX FOR IMPROVING REGENERATION OF PLANT CELLS

METHODS FOR IMPROVING PROTEIN DELIVERY TO PLANT CELLS BY BIOLISTICS

MODIFIED EXCISABLE MON87708 SOYBEAN TRANSGENIC HERBICIDE RESISTANCE LOCUS

UNNATURAL BASE PAIR COMPOSITIONS AND METHODS OF USE

COMPOSITIONS FOR INDUCING MODIFICATIONS OF TARGET ENDOGENOUS NUCLEIC ACID SEQUENCES IN NUCLEUSES OF EUKARYOTIC CELLS

PROGRAMMABLE NUCLEASES AND METHODS OF USE

POLYPEPTIDES USEFUL FOR GENE EDITING AND METHODS OF USE

METHODS AND AGENTS FOR INCREASING RBM3 EXPRESSION

METHOD OF MODULATING VEGF AND USES THEREOF

COMPOSITIONS AND METHODS FOR MAKING GUIDE NUCLEIC ACIDS

DNA MODIFYING ENZYMES AND ACTIVE FRAGMENTS AND VARIANTS THEREOF AND METHODS OF USE

CRISPR-BASED PROGRAMMABLE RNA EDITING

Cas9-Cas9 Fusion Proteins

Streptococcus Canis Cas9 as a Genome Engineering Platform with Novel PAM Specificity

NK CELL AND PREPARATION METHOD THEREFOR

OPTIMIZED POLYNUCLEOTIDES FOR PROTEIN EXPRESSION

AAV VECTORS ENCODING BASE EDITORS AND USES THEREOF

Materials and Methods for Treatment of Duchenne Muscular Dystrophy

SELF-ASSEMBLING VIRUS-LIKE PARTICLES FOR DELIVERY OF PRIME EDITORS AND METHODS OF MAKING AND USING SAME

ENGINEERED PNMA PROTEINS AND DELIVERY SYSTEMS THEREOF

ENDOGENOUS GENE REGULATION TO TREAT NEUROLOGICAL DISORDERS AND DISEASES

GLYCO-ENGINEERED CAR-T CELLS

CD5 Modified Cells Comprising Chimeric Antigen Receptors (CARs) for Treatment of Solid Tumors

COMPOSITIONS FOR THE DELIVERY OF tRNA AS NANOPARTICLES AND METHODS OF USE THEREWITH

GENETICALLY MODIFIED RAT HAVING PKHD1L1 GENE WITH POINT MUTATION AND METHODS FOR ITS CONSTRUCTION, DETECTION AND USE

ANIMAL MODELS OF RECCURRENT HEPATOCELLULAR CARCINOMA AND USES THEREOF

EDITING TMPRSS2/4 FOR DISEASE RESISTANCE IN LIVESTOCK

METHOD FOR PRODUCING GENOME-EDITED CELLS UTILIZING HOMOLOGOUS RECOMBINATION

COMPOSITIONS AND METHODS FOR DELIVERY OF THERAPEUTIC AGENTS TO ACCEPTOR CELLS

CLASS II, TYPE V CRISPR SYSTEMS

COMPOSITIONS AND METHODS FOR THE MANAGEMENT AND TREATMENT OF PHENYLKETONURIA

CORN ENDOTYPE-DERIVED POLYPEPTIDES CAPABLE OF METABOLIZING FUMONISIN

Modified Guide RNAs

Polynucleotides encoding paraoxonase fusion polypeptides

SYNTHETIC REVERSE TRANSCRIPTASES AND USES THEREOF

MEDIA AND METHODS FOR MAKING AND MAINTAINING PORCINE PLURIPOTENT STEM CELLS

BASE EDITORS AND USES THEREOF

Guide RNA That Targets A Mutant Human Guanylate Cyclase 2A Allele

COMPOSITIONS AND METHODS FOR REDUCING PAIN AND INFLAMMATION THROUGH EPIGENETIC MODULATION

Co-Delivery of a Gene Editor Construct and a Donor Template

METHODS AND COMPOSITIONS FOR IMPROVED MOLECULAR THERAPIES OF MULTIGENIC DISEASES

DNA POLYMERASE-MEDIATED GENOME EDITING

NOVEL SMALL RNA PROGRAMMABLE ENDONUCLEASE SYSTEMS WITH IMPOVED PAM SPECIFICITY AND USES THEREOF

ENGINEERED MUSCLE TARGETING COMPOSITIONS

Gene Targeting

COMPOSITIONS FOR RNA-PROTEIN TETHERING AND METHODS OF USING

MODIFIED AMINOACYL-tRNA SYNTHETASE AND USE THEREOF

METHODS AND SYSTEMS FOR CONDITIONALLY REGULATING GENE EXPRESSION

POLYPEPTIDES

MATERIALS AND METHODS FOR INCREASING GENE EDITING FREQUENCY

ENGINEERED CAS12B EFFECTOR PROTEINS AND METHODS OF USE THEREOF

OMNI-103 CRISPR NUCLEASE

Multicomponent systems for site-specific genome modifications

IMPROVED GENE THERAPY CONSTRUCTS FOR THE TREATMENT OF PROPIONIC ACIDEMIA CAUSED BY MUTATIONS IN PROPIONYL-COA CARBOXYLASE ALPHA

PAPN MUTANT, METHOD FOR SITE-DIRECTED MODIFICATION OF PAPN GENE AND USE THEREOF

ANTI-TFR:ACID SPHINGOMYELINASE FOR TREATMENT OF ACID SPHINGOMYELINASE DEFICIENCY

CELLS COMPRISING A SUPPRESSOR OF GENE EXPRESSION AND/OR A SYNTHETICPATHWAY ACTIVATOR AND/OR AN INDUCIBLE PAYLOAD

NON-VIRAL B CELL ENGINEERING METHODS

RNA-GUIDED NUCLEASES AND ACTIVE FRAGMENTS AND VARIANTS THEREOF AND METHODS OF USE

TARGETED GENOMIC BARCODING FOR TRACKING OF EDITING EVENTS

CAS9 VARIANTS WITH IMPROVED SPECIFICITY

GENE-EDITING METHODS FOR GENETIC IMPROVEMENT IN LIVESTOCK

USE OF POLYNUCLEOTIDE, PROTEIN, AND BIOLOGICAL MATERIAL IN REGULATION AND CONTROL OF PLANT TUBER DEVELOPMENT, AND RELATED PRODUCT AND PRODUCTION METHOD THEREFOR

METHOD FOR NUCLEAR GENOME EDITING USING PLASTID SELECTABLE MARKERS

MODIFIED AGROBACTERIA FOR EDITING PLANTS

INSILICO GUIDED CRISPR-CAS DRIVEN ENZYME ENGINEERING FRAMEWORK

TRANSMISSIBLE ELEMENTS COMPRISING PATHWAY MODIFICATION SYSTEMS AND EXOGENOUS NUCLEIC ACIDS FOR THE PRODUCTION OF MOLECULES OF INTEREST

SYNTHETIC MEMORY WITH INTERCEPTING RECOMBINASE FUNCTION

METHODS FOR DETERMINING INCREASED RISK OF CANCER DEVELOPMENT AND TREATING THE SAME

Precise Genome Editing Using Retrons

Polypeptides Having Nuclease Activity

EVOLVED INTEGRASES AND METHODS OF USING THE SAME FOR GENOME EDITING

GENE EDITING PAIRS

METHODS AND COMPOSITIONS FOR TREATING ANGIOPOIETIN-LIKE 3 (ANGPTL3) RELATED CONDITIONS

Engineered High Activity Omni-79 Nuclease Variants

ENDONUCLEASES THAT SELECTIVELY CLEAVE SINGLE-STRANDED NUCLEIC ACIDS AND USES THEREOF

CRISPR-based DNA Repair-Inhibiting Intratumoral Cancer Therapy

NOVEL CRISPR-ASSOCIATED (CAS) PROTEIN

METHODS FOR GENOME-EDITING AND ACTIVATION OF CELLS

ANTI-TFR:GAA AND ANTI-CD63:GAA INSERTION FOR TREATMENT OF POMPE DISEASE

BASE EDITOR AND USE THEREOF

CANCER INTERVENTION BY TARGETING GENOTYPIC DIFFERENCES USING CRISPR-CAS3 MEDIATED DELETION-EDITING

A-REPEAT MINIGENE COMPOSITIONS FOR TARGETED REPRESSION OF SELECTED CHROMOSOMAL REGIONS AND METHODS OF USE THEREOF

CRISPR-CAS9 Modified CD34+ Human Hematopoietic Stem and Progenitor Cells and Uses Thereof

GENE EDITING METHODS FOR MODULATING EXPRESSION OF ID-3, AN INHIBITOR OF DNA-BINDING TRANSCRIPTION FACTORS, THEREBY AFFECTING T-CELL FUNCTION

METHODS FOR GENERATING GENETICALLY MODIFIED ANIMALS

MUTANT MYOCILIN DISEASE MODEL AND USES THEREOF

PHOTOSELECTIVE NON-INVASIVE TARGETED GENOMIC AND EPIGENOMIC SEQUENCING OF SPATIALLY-DEFINED CELLS OR SUBCELLULAR REGIONS

SMALL NOVEL CRISPR-CAS SYSTEMS AND METHODS OF USE THEREOF

RNA-Guided Targeting of Genetic and Epigenomic Regulatory Proteins to Specific Genomic Loci

Omni-103 CRISPR Nuclease-RNA Complexes

TRACKABLE NUCLEIC ACID-GUIDED EDITING

RNA-GUIDED GENOME RECOMBINEERING AT KILOBASE SCALE

METHOD FOR EDITING BANANA GENES

GENES FOR REGULATING ROOT GROWTH ANGLE AND LOGING RESISTANCE IN MAIZE AND APPLICATIONS THEREOF

METHODS AND COMPOSITIONS FOR MODIFYING PLANT YIELD TRAITS

INCREASING GENE EDITING AND SITE-DIRECTED INTEGRATION EVENTS UTILIZING DEVELOPMENTAL PROMOTERS

COMPOSITIONS AND METHODS FOR IMPROVING THE EFFICACY OF CAS9-BASED KNOCK-IN STRATEGIES

COMPOSITION FOR MODIFYING NUCLEIC ACID SEQUENCE, AND METHOD FOR MODIFYING TARGET SITE OF NUCLEIC ACID SEQUENCE

COMPOSITIONS AND METHODS FOR TARGETING, EDITING OR MODIFYING HUMAN GENES

COMPOSITIONS AND METHODS FOR EFFICIENT IN VIVO DELIVERY

IMPROVED MODULAR PRIME EDITING WITH MODIFIED EFFECTORS AND TEMPLATES

POLYNUCLEOTIDES ENCODING ENGINEERED MEGANUCLEASES HAVING SPECIFICITY FOR RECOGNITION SEQUENCES IN THE DYSTROPHIN GENE

INCREASING DEVELOPMENTAL POTENTIAL OF HUMAN PREIMPLANTATION EMBRYOS BY REDUCING GENETIC INSTABILITY, ANEUPLOIDIES AND CHROMOSOMAL MOSAICISM

COMPOSITIONS AND METHODS FOR TREATING FAN1 ASSOCIATED TRINUCLEOTIDE REPEAT EXPANSION DISORDERS

CRISPR-MEDIATED TRANSGENE INSERTION IN NEONATAL CELLS

Improvement of Dnase1L3 Serum Half-Life

GENETICALLY MODIFIED CELLS AND METHODS OF MAKING AND USING SAME

MIR155 AS THE INTEGRATION SITE TO OVERCOME ACUTE GRAFT VERSUS HOST DISEASE OF GENE-MODIFIED IMMUNE EFFECTOR CELLS

SYSTEMS AND METHODS FOR TRANS-MODULATION OF IMMUNE CELLS BY GENETIC MANIPULATION OF IMMUNE REGULATORY GENES

Systems for nucleic acid-based data storage

DNA mapping and sequencing on linearized DNA molecules

DIFFERENTIATION OF HUMAN TISSUES WITHOUT CILIA FROM PLURIPOTENT STEM CELLS

DETECTING DISEASE-ASSOCIATED TARGET NUCLEIC ACIDS IN A MAMMAL AND TREATMENT THEREOF

CELL SUITABLE FOR GENE ENGINEERING, CELL ENGINEERING AND CELLULAR MEDICINE, AND METHOD FOR PRODUCING SAME

METHODS FOR LARGE-SIZE CHROMOSOMAL TRANSFER AND MODIFIED CHROMOSOMES AND ORGANISIMS USING SAME

Conjugates of guide RNA-Cas protein complex for genome and epigenome editing

CAS9 VARIANTS HAVING NON-CANONICAL PAM SPECIFICITIES AND USES THEREOF

METHODS AND COMPOSITIONS FOR MODIFYING ROOT ARCHITECTURE IN PLANTS

HIGH EFFICIENCY LARGE SCALE CHROMOSOMAL GENOME MANIPULATION

Target gene expression control system comprising dxCas9 and CRP derivative and preparation method therefor

MODULATING EXPRESSION OF ALAS1 (5'-AMINOLEVULINATE SYNTHASE 1) GENE

DNA-CONTAINING POLYNUCLEOTIDES AND GUIDES FOR CRISPR TYPE V SYSTEMS, AND METHODS OF MAKING AND USING THE SAME

METHODS AND COMPOSITIONS RELATED TO ENGINEERED CANNABINOID RECEPTORS

ENGINEERED NUCLEASES THAT TARGET HUMAN AND CANINE FACTOR VIII GENES AS A TREATMENT FOR HEMOPHILIA A

Polynucleotide Error Recognition Methods and Compositions

Compositions and Methods for Making Epigenetic Modifications

Adeno-Associated-Virus Rep Sequences, Vectors and Viruses

TELOMERE EXTENSION AND SUPPORTING REGIMEN FOR PROLONGED HEALTH

CELL DELIVERY COMPOSITIONS AND METHODS OF USE THEREOF

NOVEL RNA BASE EDITING COMPOSITIONS, SYSTEMS, METHODS AND USES THEREOF