ENGINEERED CRISPR/CAS12A EFFECTOR PROTEINS, AND USES THEREOF

HUMAN INDUCED PLURIPOTENT STEM CELLS-DIFFERENTIATED CARDIOMYOCYTES, METHODS OF PRODUCING THE SAME, AND USES THEREOF IN TREATING CARDIAC DISEASES

REGULATION OF CELLS AND ORGANISMS

T CELL IMMUNOTHERAPY FOR HEMATOLOGIC MALIGNANCIES HAVING AN SF3B1 MUTATION

METHODS FOR VARIANT DETECTION

REGENERATION OF SURFACE ANTIGEN-NEGATIVE CELLS

TREATMENT FOR INFLAMMATORY DISEASE

RNA EXPORT FOR MEASUREMENT AND MANIPULATION OF CELLS

ULTRA-HIGH RESOLUTION MAPPING OF 3D GENOME STRUCTURE USING REGION CAPTURE MICRO-C

ENGINEERED CAS13 FOR ULTRASENSITIVE NUCLEIC ACID DETECTION

Compositions and Methods for Making Epigenetic Modifications

ADENOVIRUS DELIVERY SYSTEM FOR CANCER TREATMENT

STRATEGIES FOR KNOCK-INS AT C3 SAFE HARBOR SITES

Reduced Expression of Sarm1 For Use In Cell Therapy

Multiplexed Genome Editing

COMPOSITIONS AND METHODS FOR THE DIAGNOSIS OF SYSTEMIC AUTOIMMUNE DISEASE

PROMOTER ELEMENTS FOR IMPROVED POLYNUCLEOTIDE EXPRESSION IN PLANTS

METHODS AND COMPOSITIONS TARGETING NUCLEUS ACCUMBENS-ASSOCIATED PROTEIN-1 FOR TREATMENT OF AUTOIMMUNE DISORDERS AND CANCERS

METHODS AND COMPOSITIONS FOR TREATING LIPOPROTEIN-RELATED DISEASES

MODULATION OF THE CRISPR ROADBLOCK

Genome Editing Compositions and Methods for Treatment of Amyotrophic Lateral Sclerosis

IN VIVO CRISPR SCREENING SYSTEM FOR DISCOVERING THERAPEUTIC TARGETS IN CD8 T CELLS

METHODS OF EDITING WITH ENGINEERED CLASS 2 TYPE V CRISPR SYSTEMS

PROBES FOR DEPLETING ABUNDANT SMALL NONCODING RNA

BASE EDITORS, COMPOSITIONS, AND METHODS FOR MODIFYING THE MITOCHONDRIAL GENOME

RNA-GUIDED NUCLEASES AND DNA BINDING PROTEINS

METHODS OF EDITING DNA METHYLATION

METHODS AND COMPOSITIONS FOR TREATING ANGIOPOIETIN-LIKE 3 (ANGPTL3) RELATED CONDITIONS

ENGINEERED NUCLEASES, COMPOSITIONS, AND METHODS OF USE THEREOF

OMNI 263, 264, 266, 268, 269, 271, 274, 275, 276, 278, 279, 280, 281, 283, 284, 286, 287, 288, 290, 291, 293, 294, 295, 296, 297, 298, 299, 300, 301, 302, 303, 304, 305, 307, 308, 309, 310, 311, 312, 313, 314, 315, 316, 317, 318, 319, 320, 321, 322, 323, 324, 325, 326, 327, 329, 330, 331, 332, 333, 334, 336, 337, 338, 339, 340, 341, 342, 343, 344, 345, 346, 347, 348, 349, 350, 351, 352, 353, 354, 356, 357, 358, 359, 360, 361, 362, 363, 364, 365, 366, 367, 368, 369, 370, 371, 372, 373, 375, 376,

NOVEL OMNI 117, 140, 150-158, 160-165, 167-177, 180-188, 191-198, 200, 201, 203, 205-209, 211-217, 219, 220, 222, 223, 226, 227, 229, 231-236, 238-245, 247, 250, 254, 256, 257, 260 AND 262 CRISPR NUCLEASES

Engineered Cas protein and use thereof

TRANSPOSABLE MOBILE ELEMENTS WITH ENHANCED GENOMIC SITE SELECTION

HEPATIC ORGANOIDS

MANUFACTURING OF STEM CELLS

ENGINEERED EFFECTOR CELLS FOR TRAFFICKING OF ALLOGENEIC CELL THERAPIES IN SOLID TUMORS

METHODS AND COMPOSITIONS FOR GENOME EDITING

Sample splitting for multiplexed detection of nucleic acids without amplification

Methods And Compositions For Increasing Homology-Directed Repair

NEW TALE PROTEIN SCAFFOLDS WITH IMPROVED ON-TARGET/OFF-TARGET ACTIVITY RATIOS

ALLELE SPECIFIC EDITING TO TREAT FUS-INDUCED NEURODEGENERATION

METHODS FOR GENE EDITING

NOVEL TYPE OF CRISPR/CAS SYSTEM

COMPOSITIONS AND METHODS FOR TRANSCRIPTIONAL ACTIVATION

REGENERATION OR REJUVENATION OF TISSUES AND ORGANS

ENGINEERED sgRNA DESIGN AND PREPARATION METHOD

MODIFIED CELLS AND METHODS OF USE THEREOF

ENGINEERED AND CHIMERIC NUCLEASES

OPTIMIZED BINUCLEASE FUSIONS AND METHODS

OPTIMIZED BINUCLEASE FUSIONS AND METHODS

COMPOSITION FOR GENE EDITING AND USE THEREOF

CPF1 PROTEIN AND ITS USE IN GENE EDITING

CLASS II, TYPE V CRISPR SYSTEMS

MOBILE ELEMENTS AND CHIMERIC CONSTRUCTS THEREOF

NRAS GENE KNOCKOUT FOR TREATMENT OF CANCER

ANTIGEN DELIVERY PLATFORM AND METHODS OF USE

HYPOIMMUNOGENIC STEM CELLS, HYPOIMMUNOGENIC CELLS DIFFERENTIATED OR DERIVED FROM STEM CELLS AND METHOD OF PREPARING SAME

METHODS RELATED TO MEGAKARYOCYTE-DERIVED EXTRACELLULAR VESICLES

IDENTIFYING AND CHARACTERIZING GENOMIC SAFE HARBORS (GSH) IN HUMANS AND MURINE GENOMES, AND VIRAL AND NON-VIRAL VECTOR COMPOSITIONS FOR TARGETED INTEGRATION AT AN IDENTIFIED GSH LOCI

CRISPR/CAS-Associated Detection Assays, Methods and Kits

SCREENING SYSTEM

KITS AND METHODS FOR QUANTITATIVE ASSESSMENT AND ENRICHMENT OF EXTRACHROMOSOMAL CIRCULAR DNA

METHOD FOR PRODUCING MODIFIED HUMAN INDUCED PLURIPOTENT STEM CELLS

OMNI 90-99, 101, 104-110, 114, 116, 118-123, 125, 126, 128, 129, and 131-138 CRISPR NUCLEASE

COMPOSITIONS AND METHODS FOR ADENO-ASSOCIATED (AAV) VIRUS DNASE EXPRESSION

ABCA4 GENOME EDITING

GENE KNOCKOUT OF NRF2 FOR TREATMENT OF CANCER

POLYNUCLEOTIDES USEFUL FOR CORRECTING MUTATIONS IN THE RAG1 GENE

Noncanonical crRNA for Highly Efficient Genome Editing

COMPOSITIONS AND METHODS OF GENOME EDITING

IMPROVED CRISPR PRIME EDITORS

ENGINEERED CAS12I NUCLEASE, EFFECTOR PROTEIN AND USE THEREOF

UNIVERSAL STEM CELL AND USES THEREOF

GENETICALLY MODIFIED CELLS FOR ALLOGENEIC CELL THERAPY TO REDUCE COMPLEMENT-MEDIATED INFLAMMATORY REACTIONS

HYPOVENTILATION PHYSICAL MODELS AND APPLICATIONS THEREOF

METHODS OF TREATING NEURODEGENERATIVE CONDITIONS AND COMPOSITIONS THEREFOR

Magnetic-Assisted Nanoparticle Delivery and Gene Editing Systems and Methods of Use

GENOME EDITING COMPOSITIONS AND METHOD FOR TREATMENT OF RETINITIS PIGMENTOSA

Compositions For and Methods of Improving Viral Vectors

MODIFIED IMMUNE CELLS AND METHODS OF USE THEREOF

METHOD

DEFINING SOURCE OF BITS IN TRIGGER FRAME FOR DISREGARD BITS AND RELEASING REDUNDANT BEAMFORMED BIT

EPIGENETIC TARGETS IN CLONAL HEMATOPOIESIS

DETECTION OF NUCLEIC ACID AND NON-NUCLEIC ACID TARGET MOLECULES

METHODS AND COMPOSITIONS FOR MODULATING A GENOME

Methods and Compositions for RNA-Directed Target DNA Modification and For RNA-Directed Modulation of Transcription

FUSION POLYPEPTIDES FOR GENETIC EDITING AND METHODS OF USE THEREOF

SERINE RECOMBINASES

METHODS AND COMPOSITIONS FOR EDITING NUCLEOTIDE SEQUENCES

Controlling Citrus Huanglongbing (HLB) by Mitigating Cell Death of the Phloem Tissues Caused by Candidatus Liberibacter Asiaticus (CLas) By Suppressing Reactive Oxygen Species (ROS)

GENE KNOCKOUT OF NRF2 FOR TREATMENT OF CANCER

GENE KNOCKOUT OF NRF2 FOR TREATMENT OF CANCER

METHODS AND COMPOSITIONS FOR PRIME EDITING RNA

SMALL DNA CLOCKS COMPRISING A COMPOSITION FOR MEASURING OR PREDICTING THE DURATION OF CELLULAR EVENTS IN CELLS

pAPN mutant and composition for site-directed modification of pAPN gene and application thereof

COMPOSITIONS AND METHODS FOR IMPROVED GENOME EDITING WITH NME2CAS9 AND NME2-SMUCAS9 VARIANTS

SYSTEMS AND METHODS FOR THE TREATMENT OF HEMOGLOBINOPATHIES

BACTERIAL COLICIN-IMMUNITY PROTEIN PROTEIN PURIFICATION SYSTEM

Precise Excisions of Portions of Exons for Treatment of Duchenne Muscular Dystrophy

CRISPR/CAS-RELATED METHODS AND COMPOSITIONS FOR KNOCKING OUT C5

GENE EDITING TO TREAT MYELOPROLIFERATIVE NEOPLASMS

METHOD FOR SITE-DIRECTED INTEGRATION OF TARGET GENE INTO SPECIFIC SITE OF IMMUNE CELL AND USE THEREOF

COMPOSITIONS FOR GENOME EDITING AND METHODS OF USE THEREOF

Method for the generation of genetically modified NK cells

PRECISION-BASED IMMUNO-MOLECULAR AUGMENTATION (PBIMA) COMPUTERIZED SYSTEM, METHOD, AND THERAPEUTIC VACCINE

NUCLEIC ACID DETECTION KIT AND DETECTION METHOD BASED ON THE PHOTO-CONTROLLED CRISPR-CAS SYSTEM

POLYSACCHARIDE OR POLYSACCHARIDE MIXTURE PRODUCED BY PAENIBACILLUS POLYMYXA

Use of Inhibitors to Increase Efficiency of Crispr/CAS Insertions

ENDONUCLEASE SYSTEMS

METHODS AND COMPOSITIONS FOR GENOME EDITING

METHOD FOR CONTROLLING PROTEIN FUNCTION

GENE DRIVE SYSTEM AND METHOD OF USE THEREOF

DIFFERENTIAL PROLIFERATION OF HUMAN HEMATOPOIETIC STEM AND PROGENITOR CELLS USING TRUNCATED ERYTHROPOIETIN RECEPTORS

SYMRK PHOSPHORYLATION FOR ROOT NODULE ORGANOGENESIS

POLYPLOID HYBRID BREEDING

OPTIMIZED PLANT CRISPR/CPF1 SYSTEMS

VECTORS AND METHODS FOR EFFICIENT CLONING AND HOMOLOGY DIRECTED REPAIR

GUIDE RNAS AND USES THEREOF

RNA-GUIDED TRANS-SPLICING OF RNA

NOVEL CRISPR-ASSOCIATED TRANSPOSON SYSTEMS AND COMPONENTS

IMPROVED PRIME EDITING SYSTEM EFFICIENCY WITH CIS-ACTING REGULATORY ELEMENTS

CAR T CELLS GENERATED BY EFFECTOR PROTEINS AND METHODS RELATED THERETO

UFMYLATION INHIBITION TO TARGET TAUOPATHY IN HUMAN NEURONS

METHODS AND PRODUCTS FOR GENETIC ENGINEERING

METHODS FOR UPREGULATING SHANK3 EXPRESSION

NME2CAS9 INLAID DOMAIN FUSION PROTEINS

METHOD OF MODULATING PCSK9 AND USES THEREOF

GENE EDITING METHODS FOR TREATING ALPHA-1 ANTITRYPSIN (AAT) DEFICIENCY

COMPOSITIONS AND METHODS FOR MULTIPLEX BASE EDITING IN HEMATOPOIETIC CELLS

METHOD FOR NARROWING EDITING WINDOW OF BASE EDITOR, BASE EDITOR, AND USE

CONVERSION-RESISTANT / CONDITION-RESISTANT TREGS AND CAR TREGS, METHODS OF MAKING AND METHODS OF USING

CYTOKINE ASSOCIATED TUMOR INFILTRATING LYMPHOCYTES COMPOSITIONS AND METHODS

DUAL ENZYME AMPLIFICATION BASED COLORIMETRIC SENSOR SYSTEM FOR ON-SITE DETECTION OF PATHOGEN

RECOGNITION SEQUENCES FOR I-CREI-DERIVED MEGANUCLEASES AND USES THEREOF

TRANSPOSON COMPOSITIONS AND METHODS OF USE THEREOF

RNA-GUIDED NUCLEASES AND ACTIVE FRAGMENTS AND VARIANTS THEREOF AND METHODS OF USE

MICRORNA-541-3P AS A THERAPEUTIC AGENT AS WELL AS ZNF101 AND CASZ1 AS THERAPEUTIC TARGETS TO LOWER PLASMA LDL-C, INCREASE PLASMA HDL-C, AND REDUCE ATHEROSCLEROSIS

EXPLOITING IL33 SECRETION AS A THERAPEUTIC TARGET IN CANCER

Chemically Modified Guide RNAs for CRISPR/CAS-Mediated Gene Correction

EVOLVED DOUBLE-STRANDED DNA DEAMINASE BASE EDITORS AND METHODS OF USE

DNASE ENZYMES ENGINEERED FOR IMPROVED STABILITY

COMPOSITIONS, SYSTEMS, AND METHODS FOR REDUCING LOW-DENSITY LIPOPROTEIN THROUGH TARGETED GENE REPRESSION

ENHANCED PROGRAMMABLE ADDITION VIA SITE-SPECIFIC TARGETING ELEMENTS SYSTEM USING A FUSION PROTEIN OF PRIME EDITOR PROTEIN AND PA01 INTEGRASE

SGF29 AS A TARGET FOR HOX/MYC DRIVEN CANCERS

IMMUNE CELLS WITH REDUCED ANDROGEN RECEPTOR (AR) LEVEL, AND METHODS OF THEIR USE TO ENHANCE ANTI-CANCER THERAPY

Treatment of Neuronal Absence Disease by Transdifferentiating Treatment

METHODS FOR IMPROVING PHAGE RESISTANCE IN CLOSTRIDIUM SPECIES

ANTIBODY-MEDIATED DELIVERY OF CAS9 TO MAMMALIAN CELLS

NOVEL TRANSCRIPTION FACTORS

Lipid nanoparticle formulations and compositions

MANIPULATION OF THE RETINOIC ACID SIGNALING PATHWAY

CRISPR-Cas13 system and use thereof

Nucleotides Comprising CasPhi Modified for Nuclear Targeting

METHODS FOR ALTERING GENE EXPRESSION FOR GENETIC DISORDERS

COMPOSITIONS AND METHODS FOR MODIFYING GENOMES

TARGET SEQUENCE SPECIFIC ALTERATION TECHNOLOGY USING NUCLEOTIDE TARGET RECOGNITION

METHODS FOR DELAYING CRISPR ACTION AND IMPROVING GENE DRIVE EFFECTIVENESS

METHODS AND COMPOSITIONS FOR INDUCING TUMOR CELL DEATH

COMPOSITIONS AND METHODS FOR NUCLEIC ACID MODIFICATIONS

ENGINEERED CASX REPRESSOR SYSTEMS

INDUCTION OF DNA STRAND BREAKS AT CHROMATIN TARGETS

BASE EDITING OF PCSK9 AND METHODS OF USING SAME FOR TREATMENT OF DISEASE

GENE EDITING OF PCSK9 OR ANGPTL3 AND COMPOSITIONS AND METHODS OF USING SAME FOR TREATMENT OF DISEASE

Gene-regulating compositions and methods for improved immunotherapy

ANTIBODY RESISTANT MODIFIED RECEPTORS TO ENHANCE CELL-BASED THERAPIES

CYTOKINE ASSOCIATED TUMOR INFILTRATING LYMPHOCYTES COMPOSITIONS AND METHODS

METHOD AND COMPOSITION FOR TEMPERATURE CONTROLLED INSECT SUPPRESSION OR MODIFICATION

Kit for breeding a TGEV infection resistant pig and use thereof

PREDICTING CELLULAR RESPONSES TO PERTURBATIONS

MGAT1 DEFICIENT CELLS AND USES THEREOF

METHODS OF PRODUCING HUMAN MILK OLIGOSACCHARIDES AND COMPOSITIONS THEREOF

Compositions And Methods For Promoting Gene Editing of CXCR4 Gene

IDENTIFICATION AND VALIDATION OF GENOMIC SAFE-HARBOR SITES IN SKELETAL MUSCLE FOR TARGETED INTEGRATION

INHIBITOR OLIGONUCLEOTIDES AND METHODS OF USE THEREOF

GENOME EDITING METHOD BASED ON CRISPR/CAS9 SYSTEM AND USE THEREOF

METHODS AND COMPOSITIONS FOR IMPROVING YIELD CHARACTERISTICS IN PLANTS

MICROBIOTA ENGINEERING

ENGINEERED POLYNUCLEOTIDES FOR CELL-TYPE OR MICROENVIRONMENT-SPECIFIC EXPRESSION

COMPOSITIONS FOR AND METHODS OF TREATING AND/OR PREVENTING GLUTARIC ACIDURIA TYPE-1

TREATING CANCER

SYSTEMS AND USES THEREOF FOR THE TREATMENT OF DMD-ASSOCIATED DISEASES

Targeting Nrip1 to Alleviate Metabolic Disease

EFFECTOR PROTEINS AND USES THEREOF

CA S9 EFFECTOR PROTEINS WITH ENHANCED STABILITY

LAUNDRY COMPOSITIONS FOR CLEANING

COMPOSITIONS AND METHODS FOR EPIGENETIC REGULATION OF HBV GENE EXPRESSION

COMPOSITIONS AND METHODS FOR EPIGENETIC REGULATION OF HBV GENE EXPRESSION

GENOME EDITING COMPOSITIONS AND METHODS FOR TREATMENT OF USHER SYNDROME TYPE 3

CELL POPULATIONS AND GENE EXPRESSION ASSOCIATED WITH IN VITRO BETA CELL DIFFERENTIATION

TREATMENT OF POLYCYTHEMIA VERA VIA CRISPR/AAV6 GENOME EDITING

NUCLEIC ACIDS ENCODING ENGINEERED MEGANUCLEASES WITH RECOGNITION SEQUENCES FOUND IN THE HUMAN T CELL RECEPTOR ALPHA CONSTANT REGION GENE

GENOME EDITING OF GROWTH, DISEASE RESISTANCE/IMMUNITY AND CUTICLE COLOR IN CRUSTACEANS

METHODS FOR MAKING GENETIC EDITS

BORONIC ACID COMPOSITIONS AND METHODS FOR TETHERING RIBONUCLEIC ACIDS IN BIOLOGICAL SAMPLES

MODULAR GENETICALLY ENGINEERED CELL AND METHODS OF GENERATION THEREOF

MODULAR PRIME EDITING SYSTEMS FOR GENOME ENGINEERING

PRIMATE DISEASE MODEL CONSTRUCTION METHOD BASED ON FAST GENE EDITION

CIRCULAR GUIDE RNAs FOR CRISPR/CAS EDITING SYSTEMS

GENE KNOCKOUT OF VARIANT NRF2 FOR TREATMENT OF CANCER

GENOME EDITING COMPOSITIONS AND METHODS FOR TREATMENT OF FANCONI ANEMIA

Split Cas9 Proteins

ENGINEERED CLASS 2 TYPE V CRISPR SYSTEMS

NOVEL TYPE I-B CRISPR-CAS SYSTEM FROM CLOSTRIDIA

RNA-GUIDED NUCLEASES AND ACTIVE FRAGMENTS AND VARIANTS THEREOF AND METHODS OF USE

RNA-GUIDED NUCLEASES AND ACTIVE FRAGMENTS AND VARIANTS THEREOF AND METHODS OF USE

TYPE I-A CRISPR-CAS3 SYSTEM FOR GENOME EDITING AND DIAGNOSTICS

NOVEL OMNI 115, 124, 127, 144-149, 159, 218, 237, 248, 251-253 AND 259 CRISPR NUCLEASES

COMPOSITIONS AND METHODS FOR TREATING ALZHEIMER'S DISEASE

MAD NUCLEASES

TARGETING VON WILLEBRAND FACTOR TO MODEL DISEASE IN HUMAN PLURIPOTENT STEM CELLS

CELL EXPANSION METHODS AND COMPOSITIONS FOR USE THEREIN

HYPOIMMUNOGENIC CELL AND METHODS OF GENERATION THEREOF

METHODS AND COMPOSITIONS FOR MODULATING A GENOME

HOMOLOGY DNA REPAIR ENHANCEMENT OF CAS DERIVATIVES COMPOSITIONS AND USES THEREOF IN GENETIC MODULATION

CASRX/CAS13D SYSTEMS TARGETING C9ORF72

NR4A3-DEFICIENT IMMUNE CELLS AND USES THEREOF

DNASE1-LIKE 3 AND ITS USE IN THERAPY

PAM-LESS ENDONUCLEASE AND GENE EDITING SYSTEM MEDIATED BY PAM-LESS ENDONUCLEASE

INCLUSION BODY MEDIATED METHOD FOR DOUBLE-STRANDED RNA PRODUCING

METHOD FOR IMPROVING GENOME EDITING

CELLS MODIFIED BY A CAS12I POLYPEPTIDE

A NOVEL RNA-PROGRAMMABLE SYSTEM FOR TARGETING POLYNUCLEOTIDES

TARGETED GENE EDITING PLATFORM INDEPENDENT OF DNA DOUBLE STRAND BREAK AND USES THEREOF

NEW METHODS AND SYSTEMS FOR TARGETED GENE MANIPULATION

METHODS AND COMPOSITIONS FOR PPO HERBICIDE TOLERANCE

PPO POLYPEPTIDES TOLERANT TO PPO-INHIBITING HERBICIDES AND USE THEREOF

NPR1 VARIANT TO ENHANCE PLANT RESISTANCE TO BIOTIC AND ABIOTIC STRESSES AND METHOD THEREOF

MODIFIED UPSTREAM OPEN READING FRAMES FOR MODULATING NPQ RELAXATION

INCREASING GENE EDITING AND SITE-DIRECTED INTEGRATION EVENTS UTILIZING MEIOTIC AND GERMLINE PROMOTERS

Improved Prime Editing System

SPLIT COMPLEMENTARY BASE EDITING SYSTEMS BASED ON BIMOLECULAR DEAMINASES AND USES THEREOF

METHOD FOR HIGH-THROUGHPUT TAG to TAA CONVERSION ON GENOME

Compositions For and Methods of Editing the Genome

MODIFICATION OF EPOR-ENCODING NUCLEIC ACIDS

Modulating Human Cas9-Specific Host Immune Response

EUBACTERIUM RECTALE CAS12A MUTANTS

LACHNOSPIRACEAE SP. CAS12A MUTANTS WITH ENHANCED CLEAVAGE ACTIVITY AT NON-CANONICAL TTTT PROTOSPACER ADJACENT MOTIFS

EPIGENETIC GENE REGULATION TO TREAT NEUROLOGICAL DISEASES AND PAIN

LENTIVIRUS-DERIVED NANOPARTICLES COMPRISING CRISPR/CAS9 RIBONUCLEOPROTEIN COMPLEXES

ADENO-ASSOCIATED VIRUS COMPOSITIONS AND METHODS OF USE THEREOF

METHOD FOR PRESERVING DEVELOPMENTAL POTENTIAL OF IMMUNE CELLS USED FOR ADOPTIVE CELLULAR THERAPIES

COMPOSITIONS COMPRISING A ZIM3 EFFECTOR AND METHODS OF USE THEREOF

TREATMENT OF PAIN

EFFECTOR PROTEIN COMPOSITIONS AND METHODS OF USE THEREOF FOR MANUFACTURING ENGINEERED HSCS

COMPOSITIONS AND METHODS FOR CD34 GENE MODIFICATION

ALLOGENIC THERAPEUTIC CELLS WITH REDUCED RISK OF IMMUNE REJECTION

DISRUPTIONS OF PDCD1, ADORA2A, AND CTLA4 GENES AND USES THEREOF

LINEAR DNA WITH ENHANCED RESISTANCE AGAINST EXONUCLEASES AND METHODS FOR THE PRODUCTION THEREOF

Efficiency of viral delivery to cell lines differentiated from induced pluripotent stem cells

Genome Editing Compositions and Methods for Treatment of Myotonic Dystrophy

SELF-INACTIVATING VECTORS FOR GENE EDITING

CRISPR/CAS-RELATED METHODS AND COMPOSITIONS FOR TREATING BETA HEMOGLOBINOPATHIES

COMPOSITIONS AND METHODS FOR CONTROLLING ADAPTIVE IMMUNITY IN BACTERIA

DNA modifying enzymes and active fragments and variants thereof and methods of use

TARGETING ONCOGENIC MUTATIONS WITH DUAL-CLEAVING ENDONUCLEASE

MODIFIED TUMOR INFILTRATING LYMPHOCYTE AND USE THEREOF

ESCHERICHIA COLI HAVING 3-HYDROXYPROPIONATE PRODUCTION ABILITY, WITH 3-HYDROXYPROPIONATE PRODUCTION GENE INSERTED INTO SAME, AND USE THEREOF

MULTIGENE CONSTRUCTS FOR TREATMENT OF AGE-RELATED MACULAR DEGENERATION AND OTHER COMPLEMENT DYSREGULATION-RELATED CONDITIONS

METHOD FOR GENE EDITING USING GENE THERAPY

GENETICALLY MODIFIED CELLS FOR ALLOGENEIC CELL THERAPY

GASDERMIN-D INHIBITORS AND USES THEREOF FOR TREATING PULMONARY VASO-OCCLUSION

COMPOSITIONS AND METHODS FOR SWITCHING ANTIBIOTIC RESISTANCE MARKERS PROGRESSIVELY FOR INTEGRATION (mSwAP-In)

RAPID ASSEMBLY OF MULTIPLEX GRNA ARRAYS

INCREASE OF PROTEIN EXPRESSION AND SECRETION BY ARTIFICIAL CO-EXPRESSION OF HDLBP/VIGILIN

POLYNUCLEOTIDES ENCODING NOVEL NUCLEASES, COMPOSITIONS THEREOF AND METHODS THEREOF FOR ELIMINATING DNA FROM PROTEIN PREPARATIONS

GUIDE RNA AND USES THEREOF

MTOR -TARGETED MODIFICATION AND USES THEREOF

SYSTEM AND METHOD FOR INDUCING CLUSTERS OF GENE REGULATORY PROTEINS TARGETED TO SPECIFIC GENOMIC LOCI

SEQUENCES AND PROMOTERS FOR USE IN PLANT CELLS AND METHODS OF MAKING AND USING SUCH SEQUENCES

MULTI-EFFECTOR CRISPR BASED DIAGNOSTIC SYSTEMS

GENOME EDITING COMPOSITIONS AND METHODS FOR TREATMENT OF RETINOPATHY

CRISPR-BASED PROTEIN BARCODING AND SURFACE ASSEMBLY

High Fidelity Restriction Endonucleases

METHOD FOR GENERATING DOUBLE-STRANDED NUCLEIC ACID

POLYPEPTIDES AND METHODS FOR MODIFYING NUCLEIC ACIDS

High Fidelity Restriction Endonucleases

SITE-SPECIFIC NUCLEASE

POLYNUCLEOTIDE INCLUDING SITE-SPECIFIC NUCLEASE EXPRESSION CASSETTE

COMPOSITIONS COMPRISING A VARIANT CAS12I3 POLYPEPTIDE AND USES THEREOF

ENZYMES WITH HEPN DOMAINS

RAPID EXPRESSION AND PURIFICATION OF THERMOSTABLE PROTEINS INCLUDING TAQ POLYMERASE

BACTERIOPHAGES WITH IMPROVED ANTIMICROBIAL ACTIVITY

MULTIPLEX BASE EDITING OF PRIMARY HUMAN NATURAL KILLER CELLS

PROMOTING TRANSPLANTATION TOLERANCE

INHIBITION OF KYNURENINE SYNTHESIS AND/OR SIGNALING TO TREAT LEUKEMIA AND MYELODYSPLASIA

COMPOSITIONS AND METHODS FOR HIGH EFFICIENCY GENOME EDITING

HEPATITIS B VIRUS (HBV) KNOCKOUTS

ANTI-ROR1 CHIMERIC ANTIGEN RECEPTORS (CARS), CELLS EXPRESSING THE CARS AND RELATED METHODS

METHODS FOR CREATING REGULATORY T CELLS (TREGS) USING GENOME ENGINEERING

GENE-MODIFYING ENDONUCLEASES

DNA SEQUENCE MODIFICATION-BASED GENE DRIVE

GENETICALLY ALTERED NFR5 RECEPTOR KINASES

GENETICALLY ALTERED NFR1 RECEPTOR KINASES

COMPOSITIONS AND METHODS TO ENHANCE HOMOLOGY-DIRECTED REPAIR AND/OR EDITING UNIFORMITY IN PLANTS

COMPOSITIONS AND METHODS FOR MODULATING HEPATOCYTE NUCLEAR FACTOR 4-ALPHA (HNF4alpha) GENE EXPRESSION

Gene Editing of Regulatory Elements

COMPOSITIONS AND METHODS FOR BCMA MODIFICATION

METHODS AND SYSTEMS FOR MODIFYING THE CRUMBS HOMOLOGUE-1 (CRB1) GENE

ENZYMES WITH RUVC DOMAINS

DELIVERY OF THERAPEUTICS IN VIVO VIA A CRISPR-BASED CASCADE SYSTEM