116334 ⎘
Hydrolases acting on ester bonds (3.1); Phosphoric monoester hydrolases (3.1.3) Protein-tyrosine-phosphatase (3.1.3.48)
SHP INHIBITOR COMPOSITIONS AND USES FOR CHIMERIC ANTIGEN RECEPTOR THERAPY
#2METHODS AND COMPOSITIONS FOR INDUCING NEURAL PLASTICITY
#3HIGH AFFINITY SIRP-ALPHA REAGENTS AND METHODS OF USING
#4PTPRS IN AUTOIMMUNITY
#5SIRP-ALPHA VARIANT CONSTRUCTS AND USES THEREOF
#6CELL PENETRATING PEPTIDES AND METHODS OF MAKING AND USING THEREOF
#7Fusion Proteins for Dephosphorylating Proteins that Regulate T Cell Activation through the TCR Signaling Pathway
#8CRISPR-Cas9 Knock-out of SHP-1/2 to Reduce T cell Exhaustion in Adoptive Cell Therapy
#9Antigen-Presenting Polypeptides with Chemical Conjugation Sites and Methods of Use Thereof
#10SYNTHETIC INTERMEMBRANE PROTEOLYSIS RECEPTORS FOR CUSTOM ANTIGEN-INDUCED TRANSCRIPTIONAL REGULATION
#11GENETICALLY MODIFIED NON-HUMAN ANIMALS EXPRESSING HUMAN EPO
#12Cell
#13CELL
#14Oncolytic viruses targeting STAT3
#15MODIFIED IPSCS
#16Methods and Materials for Producing Polyols and Electron Rich Compounds
#17PTPSIGMA-FC FUSION PROTEIN AND PHARMACEUTICAL COMPOSITION COMPRISING SAME
#18Methods of activating cytotoxic leukocytes using PTP1B and PTPN2 inhibitors
#19SYSTEMS AND METHODS FOR ENHANCED IMMUNOTHERAPIES
#20Oligomeric Compounds Comprising Bicyclic Nucleotides and Uses Thereof
#21ANTI-TUMOR FUSION PROTEIN, PREPARATION METHOD THEREFOR AND APPLICATION THEREOF
#22LOOPED PROTEINS COMPRISING CELL PENETRATING PEPTIDES
#23HYPOXIA-RESISTANT NATURAL KILLER CELLS
#24REGULATION OF POST-ISCHEMIC INFLAMMATORY RESPONSE: A NOVEL FUNCTION OF TYROSINE PHOSPHATASE STEP
#25POLYNUCLEOTIDES FOR DISRUPTING IMMUNE CELL ACTIVITY AND METHODS OF USE THEREOF
#26PTPRS AND PROTEOGLYCANS IN AUTOIMMUNE DISEASE
#27CHIMERIC INHIBITORY RECEPTOR
#28ANTIGEN-SPECIFIC T CELL RECEPTORS AND T CELL EPITOPES
#29GENE KNOCK-OUTS TO IMPROVE T CELL FUNCTION
#30Neoantigen peptide mimics
#31CELL PENETRATING PEPTIDES AND METHODS OF MAKING AND USING THEREOF
#32COMPOSITIONS AND METHODS TO MANUFACTURE TUMOR SUPPRESSOR FUSIONS
#33TARGETED SENSITIZATION OF NON-DEL(5q) MALIGNANT CELLS
#34ONCOLYTIC VIRUSES TARGETING STAT3
#35ONCOLYTIC VIRUSES TARGETING STAT3
#36Recombinant Bacteria And Uses Thereof
#37High affinity SIRP-alpha reagents and methods of using
#38A COMPOSITION COMPRISING MESENCHYMAL STEM CELLS FOR INHIBITING ADIPOGENESIS
#39Methods and compositions for inducing neural plasticity
#40CO-DELIVERY OF NUCLEIC ACIDS FOR SIMULTANEOUS SUPPRESSION AND EXPRESSION OF TARGET GENES
#41DATA PROCESSING SYSTEM FOR IDENTIFYING A THERAPEUTIC AGENT
#42Non-human animals having a humanized signal-regulatory protein gene
#43CELL
#44CELL
#45YEAST OVER-EXPRESSING PROTEIN PHOSPHATASES ASSOCIATED WITH THE HOG PATHWAY
#46METHOD OF PRODUCING LEUKOCYTES USING PTPN2 INHIBITION FOR ADOPTIVE CELL TRANSFER
#47Methods and Materials for Producing Polyols and Electron Rich Compounds
#48Oligomeric compounds comprising bicyclic nucleotides and uses thereof
#49ROBUST PANELS OF COLORECTAL CANCER BIOMARKERS
#50Cell penetrating peptides and methods of making and using thereof
#51CHIMERIC TRANSMEMBRANE RECEPTORS AND USES THEREOF
#52Pharmaceutical composition for treating or preventing Parkinson's disease comprising STT as an active ingredient
#53MOLECULAR PROFILING FOR CANCER
#54SIRP-ALPHA VARIANT CONSTRUCTS AND USES THEREOF
#55Non-human animals having a humanized signal-regulatory protein gene
#56Compositions and methods for enhancing macrophage-mediated antibody guided cancer cell or tumor eradication
#57PROTEOGLYCAN IRREGULARITIES IN ABNORMAL FIBROBLASTS AND THERAPIES BASED THEREFROM
#58METHOD FOR THE EXTRACTION OF RECOMBINANT PROTEINS
#59CO-DELIVERY OF NUCLEIC ACIDS FOR SIMULTANEOUS SUPPRESSION AND EXPRESSION OF TARGET GENES
#60CRISPR-Cas9 Knock-out of SHP-1/2 to Reduce T cell Exhaustion in Adoptive Cell Therapy
#61Genetically modified non-human animals expressing human EPO
#62SHP INHIBITOR COMPOSITIONS AND USES FOR CHIMERIC ANTIGEN RECEPTOR THERAPY
#63CELL
#64Cell
#65Compositions and methods of treating root avulsion injury
#66Oligonucleotide compositions with enhanced efficiency
#67SIGNAL TRANSDUCTION MODIFYING PROTEIN
#68Method and system for treating cancer and other age-related diseases by extending the healthspan of a human
#69Methods and compositions for in vivo induction of pancreatic beta cell formation
#70STEP-derived peptide for brain injury treatment
#71Oncolytic viruses targeting STAT3
#72Co-activation of mTOR and STAT3 pathways to promote neuronal survival and regeneration
#73Non-human animals having a humanized signal-regulatory protein gene
#74Antigen-specific T cell receptors and T cell epitopes
#75Skin-penetrating peptide and method for using same
#76Cell
#77Oligonucleotide compositions with enhanced efficiency
#78DOUBLE-STRANDED OLIGONUCLEOTIDES
#79SIRP-ALPHA VARIANT CONSTRUCTS AND USES THEREOF
#80Targeted sensitization of non-del(5q) malignant cells
#81Methods and compositions for promoting thermogenic potential
#82Cell
#83Method for measuring tyrosine phosphatase and tyrosine kinase activity
#84Selective gene therapy expression system
#85Modulators of protein tyrosine phosphatase and uses thereof
#86CLATHRIN THERAPEUTIC FOR NEUROPSYCHIATRIC DISEASES & DISORDERS
#87CLATHRIN THERAPEUTIC FOR PSYCHIATRIC DISORDERS
#88Oligomeric compounds comprising bicyclic nucleotides and uses thereof
#89PROTEIN COATING COMPOSITION
#90High affinity SIRP-alpha reagents and methods of using
#91Non-human animals having a humanized signal-regulatory protein gene
#92Methods to Prepare and Employ Binding Site Models for Modulation of Phosphatase Activity and Selectivity Determination
#93NUCLEIC ACID CONSTRUCT FOR EXPRESSING MORE THAN ONE CHIMERIC ANTIGEN RECEPTOR
#94Nucleic acid construct
#95Oligonucleotide compositions with enhanced efficiency
#96MOLECULAR PROFILING FOR CANCER
#97Co-activation of mTOR and STAT3 pathways to promote neuronal survival and regeneration
#98Cell penetrating peptides and methods of making and using thereof
#99Method and system for treating cancer and other age-related diseases by extending the healthspan of a human
#100Oligonucleotide compositions with enhanced efficiency
#101Methods and compositions for in vivo induction of pancreatic beta cell formation
#102Non-human animals having a humanized signal-regulatory protein gene
#103CDC25A inhibitor for the treatment of drug resistant cancer or for the prevention of tumor relapse
#104Modulation of PTPRA to treat arthritis
#105DIAGNOSIS OF CANCER
#106METHOD OF PRODUCING LEUKOCYTES USING PTPN2 INHIBITION FOR ADOPTIVE CELL TRANSFER
#107Cell penetrating peptides and methods of making and using thereof
#108Method and system for treating cancer cachexia
#109Pharmaceutical composition for preventing or treating neurodegenerative diseases
#110Antigen-specific T cell receptors and T cell epitopes
#111Compositions and methods of treating root avulsion injury
#112COMPOSITION TO REPURPOSE DRUGS
#113Non-human animals having a humanized signal-regulatory protein gene
#114Detection of autoantibodies reactive with pancreatic islet cell antigenic molecules and/or insulin
#115Detection of autoantibodies reactive with pancreatic islet cell antigenic molecules and/or insulin
#116SIRP-ALPHA VARIANT CONSTRUCTS AND USES THEREOF
#117CELL
#118Composition comprising a cell sample from a subject with scoliosis and a reagent for detecting PTPμ or PIPK1y
#119Cell
#120Cell
#121Compositions and methods for prostate cancer analysis
#122Generation of lineage-restricted progenitor cells from differentiated cells
#123SIRP-ALPHA VARIANT CONSTRUCTS AND USES THEREOF
#124SIRP-α immunoglobulin fusion proteins
#125Autoimmune disease treatments
#126Selective gene therapy expression system
#127Non-human animals having a humanized signal-regulatory protein gene
#128Artificial synthetic cDNA and method for detecting secondary glioblastoma
#129Compositions and methods for inhibiting the activity of LAR family phosphatases
#130Methods and compositions for treating cancer
#131Targeted sensitization of non-del(5q) malignant cells
#132Genetically modified non-human animals expressing human EPO
#133Antisense modulation of PTP1B expression
#134Fragment ligated inhibitors selective for the polo box domain of PLK1
#135Protein Tyrosine Phosphatase Mutations in Cancers
#136STEP-derived peptide for brain injury treatment
#137Methods and compositions for in vivo induction of pancreatic beta cell formation
#138Oligomeric compounds comprising bicyclic nucleotides and uses thereof
#139PTPRS AND PROTEOGLYCANS IN AUTOIMMUNE DISEASE
#140Non-human animals having a humanized signal-regulatory protein gene
#141Non-human animals having a humanized signal-regulatory protein gene
#142High affinity Sirp-alpha reagents and methods of using
#143Method for imparting environmental stress resistance to plants
#144Double-stranded oligonucleotides
#145Co-activation of mTOR and STAT3 pathways to promote neuronal survival and regeneration
#146Antisense modulation of PTP1B expression
#147STEP-derived peptide for brain injury treatment
#148Method of treatment of breast cancers over-expressing the SHP2 signature genes
#149Oligonucleotide compositions with enhanced efficiency
#150Compounds and therapeutic applications related to inhibition of dendritic cell immunoreceptor (DCIR) activity and signaling events
#151Use of -long leader sequence for transmembrane delivery of molecules
#152COMPOSITIONS AND METHODS FOR PROSTATE CANCER ANALYSIS
#153Double-stranded oligonucleotides
#154DOUBLE STRAND COMPOSITIONS COMPRISING DIFFERENTIALLY MODIFIED STRANDS FOR USE IN GENE MODULATION
#155PROTEIN TYROSINE PHOSPHATASE, NON-RECEPTOR TYPE 11 (PTPN11) AND TUMOR INITIATING CELLS
#156Antisense modulation of PTP1B expression
#157Detection of autoantibodies reactive with pancreatic islet cell antigenic molecules and/or insulin
#158Fragment ligated inhibitors selective for the polo box domain of PLK1
#159MUTANT PTP ALPHA GENE GROUP IN MALIGNANT TUMORS AND PRODUCTION METHOD
#160Compositions and Methods for Therapy and Diagnosis of Cancer
#161COMPOSITIONS AND METHODS FOR THE TREATMENT OF KRABBE AND OTHER NEURODEGENERATIVE DISEASES
#162DOUBLE-STRANDED OLIGONUCLEOTIDES
#163Protein tyrosine phosphatase mutations in cancers
#164Antisense modulation of PTP1B expression
#165Methods for Treating Autophagy-Related Disorders
#166Conjugates For Use In Hepatocyte Free Uptake Assays
#167Compositions and their uses directed to PTPRU
#168DOUBLE STRAND COMPOSITIONS COMPRISING DIFFERENTIALLY MODIFIED STRANDS FOR USE IN GENE MODULATION
#169Oligonucleotide Compositions with Enhanced Efficiency
#170Dynamic bio-nanoparticle elements
#171COMPOSITIONS AND METHODS FOR INHIBITING EXPRESSION OF PTP1B GENES
#172RNA interference mediated treatment of alzheimer's disease using short interfering nucleic acid (siNA)
#173DOUBLE-STRANDED OLIGONUCLEOTIDES
#174Protein tyrosine phosphatase inhibitors
#175RNA INTERFERENCE MEDIATED INHIBITION OF PROTEIN TYROSINE PHOSPHATASE-1B (PTP-1B) GENE EXPRESSION USING SHORT INTERFERING NUCLEIC ACID (siNA)
#176RNA Interference Mediated Inhibition of Protein Tyrosine Phosphatase-1B (PTP-1B) Gene Expression Using Short Interfering RNA
#177Compositions and methods for therapy and diagnosis of cancer
#178MODULATION OF LMW-PTPASE EXPRESSION
#179RNA interference mediated inhibition of hypoxia inducible factor 1 (HIF1) gene expression using short interfering nucleic acid (siNA)
#180RNA interference mediated inhibition of hepatitis C virus (HCV) gene expression using short interfering nucleic acid (siNA)
#181METHODS AND COMPOSITIONS FOR MODULATING FOXO1 ACTIVITY AND INSULIN SIGNALING
#182RNA interference mediated treatment of Alzheimer's disease using short interfering nucleic acid (siNA)
#183Methods and Compositions for Modulating Body Weight and for Treating Weight Disorders and Related Diseases
#184Antisense modulation of PTP1B expression
#185RNA interference mediated inhibition of Stearoyl-CoA desaturase (SCD) gene expression using short interfering nucelic acid (siNA)
#186RNA interference mediated inhibition of MYC and/or MYB gene expression using short interfering nucleic acid (siNA)
#187Products and methods for treating PTP lar diseases
#188Double-Stranded Oligonucleotides
#189Compositions and their uses directed to PTPRU
#190Oligonucleotide-containing pharmacological compositions and their use
#191RNA interference mediated inhibition of hypoxia inducible factor 1 (HIF1) gene expression using short interfering nucleic acid (siNA)
#192Oligonucleotide-containing pharmacological compositions and their use
#193Oligonucleotide-containing pharmacological compositions and their use
#194Positionally modified siRNA constructs
#195DSP-10 DUAL-SPECIFICITY PHOSPHATASE
#196EphA2, EphA4 and LMW-PTP and methods of treatment of hyperproliferative cell disorders
#197Protein tyrosine phosphatase mutations in cancers
#198Polycationic compositions for cellular delivery of polynucleotides
#199RNA interference mediated treatment of Alzheimer's disease using short interfering nucleic acid (siNA)
#200METHOD AND COMPOSITION FOR ENHANCING BONE FORMATION
#201RNA INTERFERENCE MEDIATED TREATMENT OF ALZHEIMER'S DISEASE USING SHORT INTERFERING NUCLEIC ACID (siNA)
#202Method for activating T cell protein tyrosine phosphatase for therapeutic applications
#203Rna interference mediated inhibition of xiap gene expression using short interfering nucleic acid (sina)
#204Rna interference mediated inhibition of gene expression using chemically modified short interfering nucleic acid (sina)
#205Coumarin-based amino acids for use in enzyme activity and substrate specificity assays
#206Isolated PTPMT1 protein which mediates insulin production and uses thereof
#207Crystalline phosphatase and method for use thereof
#208RNA interference mediated inhibition of cyclin dependent kinase-2 (CDK2) gene expression using short interfering nucleic acid (siNA)
#209Proteins involved in the regulation of energy homeostasis
#210RNA interference mediated inhibition of MAP kinase gene expression or expression of genes involved in MAP kinase pathway using short interfering nucleic acid (siNA)
#211Compositions and methods for the treatment of body weight disorders, including obesity
#212Transgenic mice containing NTTP1 phosphatase gene disruptions
#213Low molecular weight protein tyrosine phosphatase (LMW-PTP) as a diagnostic and therapeutic target
#214Conjugates for use in hepatocyte free uptake assays
#215Antisense modulation of PTP1B expression
#216RNA interference mediated inhibition of protein tyrosine phosphatase-1B (PTP-1B) gene expression using short interfering nucleic acid (siNA)
#217RNA interference mediated inhibtion of protein tyrosine phosphatase-1B (PTP-1B) gene expression using short interfering nucleic acid (siNA)
#218Human phosphatase RET31, and variants thereof
#219Double-stranded oligonucleotides
#220DSP-10 dual-specificity phosphatase
#221Antisense modulation of ptpn12 expression
#222Sequential delivery of oligomeric compounds
#223RNA interference mediated inhibition of stearoyl-CoA desaturase (SCD) gene expression using short interfering nucleic acid (siNA)
#224RNA interference mediated inhibition of matrix metalloproteinase 13 (MMP13) gene expression using short interfering nucleic acid (siNA)
#225RNA interference mediated inhibition of platelet derived growth factor (PDGF) and platelet derived growth factor receptor (PDGFR) gene expression using short interfering nucleic acid (siNA)
#226Polycationic compositions for cellular delivery of polynucleotides
#227Hepatocyte free uptake assays
#228Nucleic acid mediated inhibition of enterococcus infection and cytolysin toxin activity
#229RNA interference mediated treatment of Alzheimer's disease using short interfering nucleic acid (siNA)
#230RNA interference mediated inhibition of vascular cell adhesion molecule (VCAM) gene expression using short interfering nucleic acid (siNA)
#231Antisense modulation of dual specific phosphatase 5 expression
#232RNA interference mediated inhibition of GRB2 associated binding protein (GAB2) gene expression using short interfering nucleic acis (siNA)
#233RNA interference mediated treatment of polyglutamine (polyQ) repeat expansion diseases using short interfering nucleic acid (siNA)
#234RNA interference mediated inhibition of intercellular adhesion molecule (ICAM) gene expression using short interfering nucleic acid (siNA)
#235RNA interference mediated inhibition of NF-Kappa B / REL-A gene expression using short interfering nucleic acid (siNA)
#236RNA interference mediated inhibition of GPRA and AAA1 gene expression using short interfering nucleic acid (siNA)
#237RNA interference mediated inhibition of cholinergic muscarinic receptor (CHRM3) gene expression using short interfering nucleic acid (siNA)
#238RNA interference mediated inhibition of protein tyrosine phosphatase type IVA (PRL3) gene expression using short interfering nucleic acid (siNA)
#239Viral proteins capable of binding LAR
#240RNA interference mediated inhibition of B-cell CLL/Lymphoma-2 (BCL-2) gene expression using short interfering nucleic acid (siNA)
#241RNA interference mediated inhibition of epidermal growth factor receptor (EGFR) gene expression using short interfering nucleic acid (siNA)
#242RNA interference mediated inhibition of cholesteryl ester transfer protein (CEPT) gene expression using short interfering nucleic acid (siNA)
#243RNA interference mediated inhibition of 5-alpha reductase and androgen receptor gene expression using short interfering nucleic acid (siNA)
#244RNA interference mediated inhibition of ADAM33 gene expression using short interfering nucleic acid (siNA)
#245RNA interference mediated inhibition of platelet-derived endothelial cell growth factor (ECGF1) gene expression using short interfering nucleic acid (siNA)
#246RNA interference mediated inhibition of type 1 insulin-like growth factor receptor gene expression using short interfering nucleic acid (siNA)
#247Hepatocyte free uptake assays
#248RNA interference mediated inhibition of polycomb group protein EZH2 gene expression using short interfering nucleic acid (siNA)
#249RNA interference mediated inhibition of chromosome translocation gene expression using short interfering nucleic acid (siNA)
#250RNA interference mediated inhibition of angiopoietin gene expression using short interfering nucleic acid (siNA)
#251RNA interference mediated inhibition of gastric inhibitory polypeptide (GIP) and gastric inhibitory polypeptide receptor (GIPR) gene expression using short interfering nucleic acid (siNA)
#252RNA interference mediated inhibition of Myc and/or Myb gene expression using short interfering nucleic acid (siNA)
#253RNA interference mediated inhibition of proliferating cell nuclear antigen (PCNA) gene expression using short interfering nucleic acid (siNA)
#254RNA interference mediated inhibition of telomerase gene expression using short interfering nucleic acid (siNA)
#255EphA2, EphA4 and LMW-PTP and methods of treatment of hyperproliferative cell disorders
#256RNA interference mediated inhibition of interleukin and interleukin receptor gene expression using short interfering nucleic acid (SINA)
#257RNA interference mediated target discovery and target validation using short interfering nucleic acid (siNA)
#258Polynucleotides encoding the novel human phosphatase, RET31, and variants thereof
#259RNA interference mediated inhibition of wingless gene expression using short interfering nucleic acid (siNA)
#260RNA interference mediated inhibition of CXCR4 gene expression using short interfering nucleic acid (siNA)
#261RNA interference mediated inhibition of TRPM7 gene expression using short interfering nucleic acid (siNA)
#262RNA interference mediated inhibition of myostatin gene expression using short interfering nucleic acid (siNA)
#263RNA mediated inhibition connexin gene expression using short interfering nucleic acid (siNA)
#264Antisense modulation of PTP1B expression
#265RNA interference mediated inhibition of Fos gene expression using short interfering nucleic acid (siNA)
#266DSP-5 dual-specificity phosphatase
#267RNA interference mediated inhibition of vascular endothelial growth factor and vascular endothelial growth factor receptor gene expression using short interfering nucleic acid (siNA)
#268Antisense modulation of ptpn2 expression
#269RNA interference mediated inhibtion of tyrosine phosphatase-1B (PTP-1B) gene expression using short interfering nucleic acid (siNA)
#270RNA interference mediated inhibition of vascular endothelial growth factor and vascular endothelial growth factor receptor gene expression using short interfering nucleic acid (siNA)
#271Use of double-stranded ribonucleic acid for inducing cell lysis
#272RNA interference mediated inhibition of gene expression using chemically modified short interfering nucleic acid (SiNA)
#273Detection of autoantibodies reactive with pancreatic islet cell antigenic molecules and/or insulin
#274Ptp10d, tec protein tyrosine kinase and edtp homologous proteins involved in the regulation of energy homeostasis
#275PTP4A1 as a therapeutic target for fibrotic diseases and disorders including systemic sclerosis