118398 ⎘
Ligases forming carbon-nitrogen bonds (6.3); Acid—amino-acid ligases (peptide synthases)(6.3.2) Ubiquitin-protein ligase (6.3.2.19), i.e. ubiquitin-conjugating enzyme
BIFUNCTIONAL FUSION PROTEINS FOR UBIQUITIN-MEDIATED DEGRADATION
#2TARGETED DEGRADATION OF ALPHA-SYNUCLEIN
#3MODIFIED POLYNUCLEOTIDES FOR THE PRODUCTION OF BIOLOGICS AND PROTEINS ASSOCIATED WITH HUMAN DISEASE
#4MODIFIED POLYNUCLEOTIDES FOR THE PRODUCTION OF PROTEINS ASSOCIATED WITH HUMAN DISEASE
#5GENE THERAPY FOR ANGELMAN SYNDROME
#6CRISPR/CAS SYSTEM AND METHOD FOR GENOME EDITING AND MODULATING TRANSCRIPTION
#7SECRETED UBE3A FOR TREATMENT OF NEUROLOGICAL DISORDERS
#8METHODS TO PREVENT TERATOGENICITY OF IMID LIKE MOLECULES AND IMID BASED DEGRADERS/PROTACS
#9MODIFIED POLYNUCLEOTIDES FOR THE PRODUCTION OF CYTOPLASMIC AND CYTOSKELETAL PROTEINS
#10MODIFIED UBE3A GENE FOR A GENE THERAPY APPROACH FOR ANGELMAN SYNDROME
#11METHODS OF MODULATING SEED AND ORGAN SIZE IN PLANTS
#12METHODS OF DETECTING UBE3A PROTEIN
#13Small Molecule Activators of Parkin Enzyme Function
#14CIRCULAR RNA MOLECULE AND USE THEREOF IN TARGETED DEGRADATION OF PROTEIN OF INTEREST
#15TARGETED PROTEIN SILENCING USING CHIMERAS BETWEEN ANTIBODIES AND UBIQUITINATION ENZYMES
#16BIFUNCTIONAL STAPLED POLYPEPTIDES AND USES THEREOF
#17RATIONAL THERAPEUTIC TARGETING OF ONCOGENIC IMMUNE SIGNALING STATES IN MYELOID MALIGNANCIES VIA THE UBIQUITIN CONJUGATING ENZYME UBE2N
#18INCREASING ATOH1 LIFE TO DRIVE SENSORINEURAL HAIR CELL DIFFERENTIANTION
#19METHODS FOR SCREENING UBIQUITIN LIGASE AGONISTS
#20LINEAR POLYFUNCTIONAL MULTIMER BIOMOLECULE COUPLED TO POLYUBIQUITIN LINKER AND USE THEREOF
#21MODIFIED POLYNUCLEOTIDES FOR THE PRODUCTION OF BIOLOGICS AND PROTEINS ASSOCIATED WITH HUMAN DISEASE
#22IN VIVO PRODUCTION OF PROTEINS
#23CRISPR/Cas system and method for genome editing and modulating transcription
#24UBIQUITIN VARIANT MODULATORS OF SCF E3 LIGASES AND THEIR USES
#25UBIQUITIN VARIANT MODULATORS OF HECT E3 LIGASES AND THEIR USES
#26PROTEIN EXPRESSION STRAINS
#27Modified polynucleotides for the production of cytoplasmic and cytoskeletal proteins
#28METHODS OF PREVENTING AND TREATING DISEASES CHARACTERIZED BY SYNAPTIC DYSFUNCTION AND NEURODEGENERATION INCLUDING ALZHEIMER'S DISEASE
#29Cell-penetrating bacterial E3-ubiqitin-ligases for use in immunotherapy
#30In vivo production of proteins
#31Methods of modulating seed and organ size in plants
#32MODIFIED POLYNUCLEOTIDES FOR THE PRODUCTION OF PROTEINS
#33Targeted protein silencing using chimeras between antibodies and ubiquitination enzymes
#34Increasing ATOH1 life to drive sensorineural hair cell differentiation
#35Small molecule activators of Parkin enzyme function
#36BINDING INHIBITORS OF THE BETA. TRANSDUCIN REPEAT-CONTAINING PROTEIN
#37Targeting WSB1 and pVHL to treat cancer
#38Universal N-glycan binding reagent
#39MODIFIED POLYNUCLEOTIDES FOR THE PRODUCTION OF COSMETIC PROTEINS AND PEPTIDES
#40UBE2T peptides and vaccines containing the same
#41Modified Polynucleotides for the production of biologics and proteins associated with human disease
#42Probes and assays for measuring E3 ligase activity
#43Compositions and methods for modulating FMR1 expression
#44COMPOSITIONS AND METHODS FOR THE MODULATION OF DNA DAMAGE RESPONSES USING BAL1 AND BBAP
#45Cell-permeable (ICP) parkin recombinant protein and use thereof
#46Photocrosslinking reagents and methods of use thereof
#47Modified UBE3A gene for a gene therapy approach for angelman syndrome
#48BIFUNCTIONAL STAPLED POLYPEPTIDES AND USES THEREOF
#49ANTIBODIES AND METHODS FOR WNT PATHWAY-RELATED DISEASES
#50Modified polynucleotides for the production of cytoplasmic and cytoskeletal proteins
#51Modulation of UBE3A-ATS expression
#52In vivo production of proteins
#53Adenylation Enzyme Inhibitors
#54Ubiquitin variant modulators of SCF E3 ligases and their uses
#55INCREASING ATOH1 LIFE TO DRIVE SENSORINEURAL HAIR CELL DIFFERENTIANTION
#56Ubiquitin variant modulators of HECT E3 ligases and their uses
#57Universal N-glycan binding reagent
#58SUMOylation assay and related reagents
#59METHOD FOR PREDICTING RESPONSE TO THERAPY FOR CANCER
#60Development of Improved Cell-Permeable (iCP) Parkin Recombinant Protein as a Protein-Based Anti-Neurodegenerative Agent for the Treatment of Parkinson's Disease-Associated Phenotypes by Utilizing BBB-Penetrating Protein Delivery System MITT, Enabled by Advanced Macromolecule Transduction Domain (aMTD)
#61Targeting WSB1 and pVHL to treat cancer
#62RECURRENT TRANSFORMING UBR5-ZNF423 FUSION GENE IN EBV-ASSOCIATED NASOPHARYNGEAL CARCINOMA
#63MARKERS ASSOCIATED WITH HUMAN DOUBLE MINUTE 2 INHIBITORS
#64Cell-penetrating bacterial E3-ubiqitin-ligases for use in immunotherapy
#65Methods of modulating ubiquitin ligase activity
#66Methods of modulating seed and organ size in plants
#67LAFORA'S DISEASE GENE
#68Parkin ligase activation methods and compositions
#69Modified polynucleotides for the production of cytoplasmic and cytoskeletal proteins
#70Modified polynucleotides for the production of proteins
#71PROTEIN INVOLVED IN DNA REPLICATION, AND MODULATION OF ITS ACTIVITY
#72ATSP1, AN E3 UBIQUITIN LIGASE, AND ITS USE
#73Modulators of itch ubiquitinase activity
#74Modified polynucleotides for the production of biologics and proteins associated with human disease
#75In vivo production of proteins
#76ADP-ribose detection reagents
#77ENGINEERED LOWER EUKARYOTIC HOST STRAINS DEFICIENT IN GRR1 ACTIVITY FOR RECOMBINANT PROTEIN
#78Designer Ubiquitin Ligases for Regulation of Intracellular Pathogenic Proteins
#79Recurrent transforming UBR5-ZNF423 fusion gene in EBV-associated nasopharyngeal carcinoma
#80Pharmaceutical composition containing core factor involved in proliferation and differentiation of central nervous cell
#81Methods of modulating ubiquitin ligase activity
#82Methods and Kits to Create Protein Substrate˜HECT-Ubiquitin Ligase Pairs
#83UBE2T peptides and vaccines containing the same
#84Modified polynucleotides for the production of cosmetic proteins and peptides
#85Mutations of the parkin gene, compositions, methods and uses
#86Compositions and methods for the modulation of DNA damage responses using BAL1 and BBAP
#87Catalytic Tagging System to Study Macro-Molecular Interactions Using Engineered Ubiquitin Ligase and Ubiquitin-Like Proteins to Facilitate Substrate Identification
#88Transcriptional repression leading to parkinson's disease
#89Antibodies and methods for WNT pathway-related diseases
#90Method for therapeutic angiogenesis
#91Methods and compositions for inhibiting neddylation of proteins
#92High affinity SUMO traps
#93Modified polynucleotides encoding SIAH E3 ubiquitin protein ligase 1
#94Modified polynucleotides encoding hepatitis A virus cellular receptor 2
#95Plants having stress related traits and methods for making the same
#96Engineered E2 for increasing the content of free LYS11-linked ubiquitin
#97GENES ENCODING PROTEINS ABLE TO ENHANCE HEAT RESISTANCE OF PLANTS AND MICROORGANISMS AND USES THEREOF
#98Bifunctional stapled polypeptides and uses thereof
#99Novel Ubiquitin-Isopeptide Probes
#100PHARMACEUTICAL COMPOSITION CONTAINING NUCLEAR FACTOR INVOLVED IN PROLIFERATION AND DIFFERENTIATION OF CENTRAL NEURONAL CELLS
#101Transcriptional repression leading to Parkinson's disease
#102Treatment and prevention of pathological conditions using iduna related techniques and compositions
#103Method for therapeutic angiogenesis
#104Lafora's disease gene
#105Mutations of the parkin gene
#106E2EPF Ubiquitin Carrier Protein-Von Hippel-Lindau Interaction and Uses Thereof
#107Designer Ubiquitin Ligases For Regulation Of Intracellular Pathogenic Proteins
#108Method for increasing immunoreactivity
#109DSRNA COMPOSITIONS AND METHODS FOR TREATING HPV INFECTIONS
#11027877, 18080, 14081, 32140, 50352, 16658, 14223, 16002, 50566, 65552 and 65577 molecules and uses therefor
#111Modulators of Itch ubiquitinase activity
#112Compounds and methods for modulating activation of NF-κB
#113SiRNA silencing of genes expressed in cancer
#114Novel Gene Therapy Approach For Treating The Metabolic Disorder Obesity
#115E2epf Ubiquitin Carrier Protein-Von Hippel-Lindau Interaction and Uses Thereof
#116Targeted ubiquitination of proteins and screening methods using a new class of ubiquitin ligase proteins
#11727877, 18080, 14081, 32140, 50352, 16658, 14223, 16002, 50566, 65552 and 65577 molecules and uses therefor
#118Posh nucleic acids, polypeptides and related methods
#119Antagonist of TEB4 and Methods of Use
#120Compounds and methods for modulating activation of NF-κB
#121Lafora's disease gene
#122Posh polypeptides, complexes and related methods
#123Mule: Mcl-1 ubiquitination ligase E3
#124Slim compositions and methods of use thereof
#12527877, 18080, 14081, 32140, 50352, 16658, 14223, 16002, 50566, 65552, and 65577 molecules and uses therefor
#126Inhibition of E3-ubiquitin ligase HAKAI for treatment of proliferative disorders
#127Diagnosis and treatment of fanconi's anemia
#128POSH nucleic acids, polypeptides and related methods
#129Posh nucleic acids, polypeptides and related methods
#130Compositions and methods for the modulation of viral maturation
#131Inhibition of E3-ubiquitin ligase HAKAI for treatment of proliferative disorders