ClassID:

118398

C12Y603/02019 - CPC Classification

Classification description:

Ligases forming carbon-nitrogen bonds (6.3); Acid—amino-acid ligases (peptide synthases)(6.3.2) Ubiquitin-protein ligase (6.3.2.19), i.e. ubiquitin-conjugating enzyme

Recent Application in this class:
#1
20250297240
2025-09-25

BIFUNCTIONAL FUSION PROTEINS FOR UBIQUITIN-MEDIATED DEGRADATION

#2
20250059527
2025-02-20

TARGETED DEGRADATION OF ALPHA-SYNUCLEIN

#3
20250018062
2025-01-16

MODIFIED POLYNUCLEOTIDES FOR THE PRODUCTION OF BIOLOGICS AND PROTEINS ASSOCIATED WITH HUMAN DISEASE

#4
20240327476
2024-10-03

MODIFIED POLYNUCLEOTIDES FOR THE PRODUCTION OF PROTEINS ASSOCIATED WITH HUMAN DISEASE

#5
20240261438
2024-08-08

GENE THERAPY FOR ANGELMAN SYNDROME

#6
20240247262
2024-07-25

CRISPR/CAS SYSTEM AND METHOD FOR GENOME EDITING AND MODULATING TRANSCRIPTION

#7
20240216536
2024-07-04

SECRETED UBE3A FOR TREATMENT OF NEUROLOGICAL DISORDERS

#8
20240142437
2024-05-02

METHODS TO PREVENT TERATOGENICITY OF IMID LIKE MOLECULES AND IMID BASED DEGRADERS/PROTACS

#9
20240131193
2024-04-25

MODIFIED POLYNUCLEOTIDES FOR THE PRODUCTION OF CYTOPLASMIC AND CYTOSKELETAL PROTEINS

#10
20230277684
2023-09-07

MODIFIED UBE3A GENE FOR A GENE THERAPY APPROACH FOR ANGELMAN SYNDROME

#11
20230203519
2023-06-29

METHODS OF MODULATING SEED AND ORGAN SIZE IN PLANTS

#12
20230184780
2023-06-15

METHODS OF DETECTING UBE3A PROTEIN

#13
20230128765
2023-04-27

Small Molecule Activators of Parkin Enzyme Function

#14
20230042694
2023-02-09

CIRCULAR RNA MOLECULE AND USE THEREOF IN TARGETED DEGRADATION OF PROTEIN OF INTEREST

#15
20220348644
2022-11-03

TARGETED PROTEIN SILENCING USING CHIMERAS BETWEEN ANTIBODIES AND UBIQUITINATION ENZYMES

#16
20220306708
2022-09-29

BIFUNCTIONAL STAPLED POLYPEPTIDES AND USES THEREOF

#17
20220267753
2022-08-25

RATIONAL THERAPEUTIC TARGETING OF ONCOGENIC IMMUNE SIGNALING STATES IN MYELOID MALIGNANCIES VIA THE UBIQUITIN CONJUGATING ENZYME UBE2N

#18
20220259602
2022-08-18

INCREASING ATOH1 LIFE TO DRIVE SENSORINEURAL HAIR CELL DIFFERENTIANTION

#19
20210382054
2021-12-09

METHODS FOR SCREENING UBIQUITIN LIGASE AGONISTS

#20
20210347827
2021-11-11

LINEAR POLYFUNCTIONAL MULTIMER BIOMOLECULE COUPLED TO POLYUBIQUITIN LINKER AND USE THEREOF

#21
20210299278
2021-09-30

MODIFIED POLYNUCLEOTIDES FOR THE PRODUCTION OF BIOLOGICS AND PROTEINS ASSOCIATED WITH HUMAN DISEASE

#22
20210077634
2021-03-18

IN VIVO PRODUCTION OF PROTEINS

#23
20200308581
2020-10-01

CRISPR/Cas system and method for genome editing and modulating transcription

#24
20200299342
2020-09-24

UBIQUITIN VARIANT MODULATORS OF SCF E3 LIGASES AND THEIR USES

#25
20200277346
2020-09-03

UBIQUITIN VARIANT MODULATORS OF HECT E3 LIGASES AND THEIR USES

#26
20200157155
2020-05-21

PROTEIN EXPRESSION STRAINS

#27
20200155706
2020-05-21

Modified polynucleotides for the production of cytoplasmic and cytoskeletal proteins

#28
20200138921
2020-05-07

METHODS OF PREVENTING AND TREATING DISEASES CHARACTERIZED BY SYNAPTIC DYSFUNCTION AND NEURODEGENERATION INCLUDING ALZHEIMER'S DISEASE

#29
20200038493
2020-02-06

Cell-penetrating bacterial E3-ubiqitin-ligases for use in immunotherapy

#30
20190314527
2019-10-17

In vivo production of proteins

#31
20190300897
2019-10-03

Methods of modulating seed and organ size in plants

#32
20190240351
2019-08-08

MODIFIED POLYNUCLEOTIDES FOR THE PRODUCTION OF PROTEINS

#33
20190233507
2019-08-01

Targeted protein silencing using chimeras between antibodies and ubiquitination enzymes

#34
20190203210
2019-07-04

Increasing ATOH1 life to drive sensorineural hair cell differentiation

#35
20190169158
2019-06-06

Small molecule activators of Parkin enzyme function

#36
20190106460
2019-04-11

BINDING INHIBITORS OF THE BETA. TRANSDUCIN REPEAT-CONTAINING PROTEIN

#37
20190010501
2019-01-10

Targeting WSB1 and pVHL to treat cancer

#38
20190008934
2019-01-10

Universal N-glycan binding reagent

#39
20180360995
2018-12-20

MODIFIED POLYNUCLEOTIDES FOR THE PRODUCTION OF COSMETIC PROTEINS AND PEPTIDES

#40
20180360938
2018-12-20

UBE2T peptides and vaccines containing the same

#41
20180311381
2018-11-01

Modified Polynucleotides for the production of biologics and proteins associated with human disease

#42
20180258462
2018-09-13

Probes and assays for measuring E3 ligase activity

#43
20180256749
2018-09-13

Compositions and methods for modulating FMR1 expression

#44
20180223288
2018-08-09

COMPOSITIONS AND METHODS FOR THE MODULATION OF DNA DAMAGE RESPONSES USING BAL1 AND BBAP

#45
20180171322
2018-06-21

Cell-permeable (ICP) parkin recombinant protein and use thereof

#46
20180170878
2018-06-21

Photocrosslinking reagents and methods of use thereof

#47
20180104358
2018-04-19

Modified UBE3A gene for a gene therapy approach for angelman syndrome

#48
20180100001
2018-04-12

BIFUNCTIONAL STAPLED POLYPEPTIDES AND USES THEREOF

#49
20180066067
2018-03-08

ANTIBODIES AND METHODS FOR WNT PATHWAY-RELATED DISEASES

#50
20170368200
2017-12-28

Modified polynucleotides for the production of cytoplasmic and cytoskeletal proteins

#51
20170362592
2017-12-21

Modulation of UBE3A-ATS expression

#52
20170348436
2017-12-07

In vivo production of proteins

#53
20170327549
2017-11-16

Adenylation Enzyme Inhibitors

#54
20170321205
2017-11-09

Ubiquitin variant modulators of SCF E3 ligases and their uses

#55
20170314027
2017-11-02

INCREASING ATOH1 LIFE TO DRIVE SENSORINEURAL HAIR CELL DIFFERENTIANTION

#56
20170275341
2017-09-28

Ubiquitin variant modulators of HECT E3 ligases and their uses

#57
20170128554
2017-05-11

Universal N-glycan binding reagent

#58
20170096698
2017-04-06

SUMOylation assay and related reagents

#59
20170045520
2017-02-16

METHOD FOR PREDICTING RESPONSE TO THERAPY FOR CANCER

#60
20170029798
2017-02-02

Development of Improved Cell-Permeable (iCP) Parkin Recombinant Protein as a Protein-Based Anti-Neurodegenerative Agent for the Treatment of Parkinson's Disease-Associated Phenotypes by Utilizing BBB-Penetrating Protein Delivery System MITT, Enabled by Advanced Macromolecule Transduction Domain (aMTD)

#61
20160326532
2016-11-10

Targeting WSB1 and pVHL to treat cancer

#62
20160319360
2016-11-03

RECURRENT TRANSFORMING UBR5-ZNF423 FUSION GENE IN EBV-ASSOCIATED NASOPHARYNGEAL CARCINOMA

#63
20160289770
2016-10-06

MARKERS ASSOCIATED WITH HUMAN DOUBLE MINUTE 2 INHIBITORS

#64
20160206713
2016-07-21

Cell-penetrating bacterial E3-ubiqitin-ligases for use in immunotherapy

#65
20160201049
2016-07-14

Methods of modulating ubiquitin ligase activity

#66
20160194651
2016-07-07

Methods of modulating seed and organ size in plants

#67
20160177393
2016-06-23

LAFORA'S DISEASE GENE

#68
20160160205
2016-06-09

Parkin ligase activation methods and compositions

#69
20160158385
2016-06-09

Modified polynucleotides for the production of cytoplasmic and cytoskeletal proteins

#70
20160151516
2016-06-02

Modified polynucleotides for the production of proteins

#71
20160122742
2016-05-05

PROTEIN INVOLVED IN DNA REPLICATION, AND MODULATION OF ITS ACTIVITY

#72
20160108416
2016-04-21

ATSP1, AN E3 UBIQUITIN LIGASE, AND ITS USE

#73
20160084838
2016-03-24

Modulators of itch ubiquitinase activity

#74
20160075733
2016-03-17

Modified polynucleotides for the production of biologics and proteins associated with human disease

#75
20150376648
2015-12-31

In vivo production of proteins

#76
20150355172
2015-12-10

ADP-ribose detection reagents

#77
20150299690
2015-10-22

ENGINEERED LOWER EUKARYOTIC HOST STRAINS DEFICIENT IN GRR1 ACTIVITY FOR RECOMBINANT PROTEIN

#78
20150267187
2015-09-24

Designer Ubiquitin Ligases for Regulation of Intracellular Pathogenic Proteins

#79
20150240311
2015-08-27

Recurrent transforming UBR5-ZNF423 fusion gene in EBV-associated nasopharyngeal carcinoma

#80
20150232826
2015-08-20

Pharmaceutical composition containing core factor involved in proliferation and differentiation of central nervous cell

#81
20150210998
2015-07-30

Methods of modulating ubiquitin ligase activity

#82
20150175998
2015-06-25

Methods and Kits to Create Protein Substrate˜HECT-Ubiquitin Ligase Pairs

#83
20150174223
2015-06-25

UBE2T peptides and vaccines containing the same

#84
20150166616
2015-06-18

Modified polynucleotides for the production of cosmetic proteins and peptides

#85
20150074836
2015-03-12

Mutations of the parkin gene, compositions, methods and uses

#86
20150020221
2015-01-15

Compositions and methods for the modulation of DNA damage responses using BAL1 and BBAP

#87
20150010525
2015-01-08

Catalytic Tagging System to Study Macro-Molecular Interactions Using Engineered Ubiquitin Ligase and Ubiquitin-Like Proteins to Facilitate Substrate Identification

#88
20140378536
2014-12-25

Transcriptional repression leading to parkinson's disease

#89
20140328859
2014-11-06

Antibodies and methods for WNT pathway-related diseases

#90
20140234285
2014-08-21

Method for therapeutic angiogenesis

#91
20140179593
2014-06-26

Methods and compositions for inhibiting neddylation of proteins

#92
20140165222
2014-06-12

High affinity SUMO traps

#93
20140141068
2014-05-22

Modified polynucleotides encoding SIAH E3 ubiquitin protein ligase 1

#94
20140105966
2014-04-17

Modified polynucleotides encoding hepatitis A virus cellular receptor 2

#95
20130067617
2013-03-14

Plants having stress related traits and methods for making the same

#96
20130065273
2013-03-14

Engineered E2 for increasing the content of free LYS11-linked ubiquitin

#97
20130055470
2013-02-28

GENES ENCODING PROTEINS ABLE TO ENHANCE HEAT RESISTANCE OF PLANTS AND MICROORGANISMS AND USES THEREOF

#98
20120270800
2012-10-25

Bifunctional stapled polypeptides and uses thereof

#99
20120184482
2012-07-19

Novel Ubiquitin-Isopeptide Probes

#100
20120134969
2012-05-31

PHARMACEUTICAL COMPOSITION CONTAINING NUCLEAR FACTOR INVOLVED IN PROLIFERATION AND DIFFERENTIATION OF CENTRAL NEURONAL CELLS

#101
20120122958
2012-05-17

Transcriptional repression leading to Parkinson's disease

#102
20120121559
2012-05-17

Treatment and prevention of pathological conditions using iduna related techniques and compositions

#103
20120107297
2012-05-03

Method for therapeutic angiogenesis

#104
20120070826
2012-03-22

Lafora's disease gene

#105
20120064598
2012-03-15

Mutations of the parkin gene

#106
20110213016
2011-09-01

E2EPF Ubiquitin Carrier Protein-Von Hippel-Lindau Interaction and Uses Thereof

#107
20100278826
2010-11-04

Designer Ubiquitin Ligases For Regulation Of Intracellular Pathogenic Proteins

#108
20100260808
2010-10-14

Method for increasing immunoreactivity

#109
20100249052
2010-09-30

DSRNA COMPOSITIONS AND METHODS FOR TREATING HPV INFECTIONS

#110
20100098713
2010-04-22

27877, 18080, 14081, 32140, 50352, 16658, 14223, 16002, 50566, 65552 and 65577 molecules and uses therefor

#111
20090306187
2009-12-10

Modulators of Itch ubiquitinase activity

#112
20090233855
2009-09-17

Compounds and methods for modulating activation of NF-κB

#113
20090149403
2009-06-11

SiRNA silencing of genes expressed in cancer

#114
20090110661
2009-04-30

Novel Gene Therapy Approach For Treating The Metabolic Disorder Obesity

#115
20080269158
2008-10-30

E2epf Ubiquitin Carrier Protein-Von Hippel-Lindau Interaction and Uses Thereof

#116
20080261241
2008-10-23

Targeted ubiquitination of proteins and screening methods using a new class of ubiquitin ligase proteins

#117
20080234468
2008-09-25

27877, 18080, 14081, 32140, 50352, 16658, 14223, 16002, 50566, 65552 and 65577 molecules and uses therefor

#118
20080187538
2008-08-07

Posh nucleic acids, polypeptides and related methods

#119
20080090775
2008-04-17

Antagonist of TEB4 and Methods of Use

#120
20070208167
2007-09-06

Compounds and methods for modulating activation of NF-κB

#121
20070184442
2007-08-09

Lafora's disease gene

#122
20070122807
2007-05-31

Posh polypeptides, complexes and related methods

#123
20060264366
2006-11-23

Mule: Mcl-1 ubiquitination ligase E3

#124
20060246543
2006-11-02

Slim compositions and methods of use thereof

#125
20060240464
2006-10-26

27877, 18080, 14081, 32140, 50352, 16658, 14223, 16002, 50566, 65552, and 65577 molecules and uses therefor

#126
20060188989
2006-08-24

Inhibition of E3-ubiquitin ligase HAKAI for treatment of proliferative disorders

#127
20060070134
2006-03-30

Diagnosis and treatment of fanconi's anemia

#128
20060035213
2006-02-16

POSH nucleic acids, polypeptides and related methods

#129
20060019240
2006-01-26

Posh nucleic acids, polypeptides and related methods

#130
20050181355
2005-08-18

Compositions and methods for the modulation of viral maturation

#131
20050049214
2005-03-03

Inhibition of E3-ubiquitin ligase HAKAI for treatment of proliferative disorders