ClassID:

109048

C12N15/113 - page 19 - CPC Classification

Classification description:

Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor; Recombinant DNA-technology; DNA or RNA fragments; Modified forms thereof Non-coding nucleic acids modulating the expression of genes, e.g. antisense oligonucleotides

Recent Application in this class:
#5401
20200237915
2020-07-30

Cytomegalovirus vectors eliciting T cells restricted by major histocompatibility complex E molecules

#5402
20200237802
2020-07-30

Oligonucleotides to treat eye disease

#5403
20200237800
2020-07-30

METHODS AND COMPOSITIONS FOR THE TREATMENT OF INFLAMMATORY DISEASE

#5404
20200237663
2020-07-30

Method and composition for targeted delivery of therapeutic agents

#5405
20200236949
2020-07-30

Control of hemipteran pests using RNA molecules

#5406
20200231985
2020-07-23

COMPOSITIONS AND METHODS TO CONTROL INSECT PESTS

#5407
20200231975
2020-07-23

NOVEL TYPE VI CRISPR ORTHOLOGS AND SYSTEMS

#5408
20200231971
2020-07-23

Methods for treatment of polycystic kidney disease

#5409
20200231970
2020-07-23

Gene therapies for lysosomal disorders

#5410
20200231969
2020-07-23

Reducing intron retention

#5411
20200231968
2020-07-23

COMPOSITIONS AND METHODS FOR INHIBITING EXPRESSION OF FACTOR V

#5412
20200231967
2020-07-23

Double-stranded RNA molecule targeting CKIP-1 and use thereof

#5413
20200231966
2020-07-23

Agents useful in treating facioscapulohumeral muscular dystrophy

#5414
20200231954
2020-07-23

Gene therapies for lysosomal disorders

#5415
20200231695
2020-07-23

Use of Circ-CDH1 inhibitors

#5416
20200230168
2020-07-23

Nucleic acid oligomers and uses therefor

#5417
20200224272
2020-07-16

HOMEOBOX TRANSCRIPTION FACTOR VENTX REGULATES DIFFERENTIATION AND MATURATION OF HUMAN DENDRITIC CELLS

#5418
20200224250
2020-07-16

METHODS FOR DETECTING AND TREATING LOW-VIRULENCE INFECTIONS

#5419
20200224221
2020-07-16

GENOME EDITING METHOD

#5420
20200224203
2020-07-16

ANTISENSE OLIGONUCLEOTIDE DIRECTED REMOVAL OF PROTEOLYTIC CLEAVAGE SITES, THE HCHWA-D MUTATION, AND TRINUCLEOTIDE REPEAT EXPANSIONS

#5421
20200224199
2020-07-16

Methods and compositions for modulating splicing

#5422
20200224198
2020-07-16

COMPOSITIONS AND METHODS FOR MODULATING HBV EXPRESSION

#5423
20200224197
2020-07-16

Functional nucleic acid molecule and use thereof

#5424
20200224196
2020-07-16

Single-stranded oligonucleotide

#5425
20200224195
2020-07-16

METHODS OF MODULATING FAM46A

#5426
20200222557
2020-07-16

Compositions and methods of modulating macrophage activity

#5427
20200222467
2020-07-16

Pharmaceutical carriers containing miRNAs for use in the treatment of fibrotic diseases caused by hyperglycemia

#5428
20200222443
2020-07-16

Composition for prevention or treatment of spinocerebellar ataxia type 36

#5429
20200222410
2020-07-16

NUCLEOCYTOPLASMIC REGULATOR OF AUTOPHAGY-ASSOCIATED TRANSCRIPTION FACTORS

#5430
20200222324
2020-07-16

Hybridosomes, compositions comprising the same, processes for their production and uses thereof

#5431
20200216912
2020-07-09

METHOD FOR SUPPRESSING BRAIN METASTASIS

#5432
20200216860
2020-07-09

DELIVERY OF A GENE-EDITING SYSTEM WITH A SINGLE RETROVIRAL PARTICLE AND METHODS OF GENERATION AND USE

#5433
20200216857
2020-07-09

MATERIALS AND METHODS FOR TREATMENT OF SPINOCEREBELLAR ATAXIA TYPE 2 (SCA2) AND OTHER SPINOCEREBELLAR ATAXIA TYPE 2 PROTEIN (ATXN2) GENE RELATED CONDITIONS OR DISORDERS

#5434
20200216848
2020-07-09

Variant RNAi

#5435
20200216847
2020-07-09

Inhibition of LET7I as a means to enhance the protective effect of progesterone against stroke

#5436
20200216846
2020-07-09

Antisense Compounds and Uses Thereof

#5437
20200216845
2020-07-09

ANTISENSE OLIGONUCLEOTIDES FOR MODULATING RELA EXPRESSION

#5438
20200216844
2020-07-09

SERPINC1 iRNA COMPOSITIONS AND METHODS OF USE THEREOF

#5439
20200216843
2020-07-09

Systems and methods for treating alpha 1-antitrypsin (A1AT) deficiency

#5440
20200215113
2020-07-09

CHEMICALLY MODIFIED OLIGONUCLEOTIDES

#5441
20200208174
2020-07-02

Sequential gene editing in primary immune cells

#5442
20200208155
2020-07-02

Engineered nucleic acid-targeting nucleic acids

#5443
20200208154
2020-07-02

ALLELE SELECTIVE INHIBITION OF MUTANT C9ORF72 FOCI EXPRESSION BY DUPLEX RNAS TARGETING THE EXPANDED HEXANUCLEOTIDE REPEAT

#5444
20200208153
2020-07-02

Long noncoding RNAs in pulmonary airway inflammation

#5445
20200208152
2020-07-02

STABILIZED SARNA COMPOSITIONS AND METHODS OF USE

#5446
20200208151
2020-07-02

Compositions and methods for messenger RNA inhibitors

#5447
20200208150
2020-07-02

METHODS FOR TREATING OR PREVENTING CONTACT-ACTIVATION PATHWAY-ASSOCIATED DISEASES USING iRNA COMPOSITIONS TARGETING FACTOR XII (HAGEMAN FACTOR) (F12)

#5448
20200208149
2020-07-02

Alpha-1 antitrypsin (AAT) RNAi agents, compositions including AAT RNAi agents, and methods of use

#5449
20200208135
2020-07-02

Using nucleosome interacting protein domains to enhance targeted genome modification

#5450
20200208134
2020-07-02

Means and methods for producing phosphate containing capsular polysaccharides

#5451
20200208109
2020-07-02

Platelets as delivery agents

#5452
20200206344
2020-07-02

METHODS FOR MODULATING THE INTERACTION BETWEEN EWS-FLI1 AND BAF COMPLEXES

#5453
20200206327
2020-07-02

Hippo pathway deficiency reverses systolic heart failure post-infarction

#5454
20200206258
2020-07-02

LACTATE DEHYDROGENASE A (LDHA) iRNA COMPOSITIONS AND METHODS OF USE THEREOF

#5455
20200206256
2020-07-02

Methods of treatment of cancer with reduced UBB expression

#5456
20200206135
2020-07-02

INSTANT THICKENED DRY FOOD COMPOSITIONS

#5457
20200205416
2020-07-02

ALTERING MICROBIAL POPULATIONS & MODIFYING MICROBIOTA

#5458
20200199627
2020-06-25

Adeno-associated virus (AAV) producer cell line and related methods

#5459
20200199625
2020-06-25

RNAi induced reduction of ataxin-3 for the treatment of Spinocerebellar ataxia type 3

#5460
20200199622
2020-06-25

Viral vector production

#5461
20200199617
2020-06-25

Artificial genome manipulation for gene expression regulation

#5462
20200199607
2020-06-25

Inducible expression of genes in algae

#5463
20200199595
2020-06-25

Allele-specific therapy for Huntington disease haplotypes

#5464
20200199594
2020-06-25

tRNA derived small RNAs (tsRNAs) involved in cell viability

#5465
20200199593
2020-06-25

Expression control using a regulatable intron

#5466
20200199592
2020-06-25

siRNA Therapy for Transthyretin (TTR) Related Ocular Amyloidosis

#5467
20200199591
2020-06-25

Apolipoprotein C3 (APOC3) iRNA compositions and methods of use thereof

#5468
20200199590
2020-06-25

Antisense oligonucleotides for inducing exon skipping and methods of use thereof

#5469
20200199589
2020-06-25

Compounds and methods for reducing Tau expression

#5470
20200199588
2020-06-25

Polycomb-Associated Non-Coding RNAs

#5471
20200199587
2020-06-25

Functionally-interdependent shape switching nucleic acid nanoparticles

#5472
20200199586
2020-06-25

Targeted RNA editing

#5473
20200199582
2020-06-25

Method for the construction of specific promoters

#5474
20200199570
2020-06-25

Compositions and methods for non-antibiotic treating of bacterial infections by blocking or disrupting bacterial genes involved in virulence or viability

#5475
20200199552
2020-06-25

Variant Cas9 polypeptides comprising internal insertions

#5476
20200199064
2020-06-25

Cationic lipids for therapeutic agent delivery formulations

#5477
20200197535
2020-06-25

EXTRACELLULAR VESICLES FOR AGENT DELIVERY

#5478
20200197526
2020-06-25

REFILLABLE DRUG DELIVERY DEVICES AND METHODS OF USE THEREOF

#5479
20200197516
2020-06-25

Antagonists of Products of the HS.459642 Unigene Cluster for the Inhibition of Proliferation, Development or Differentiation of Stem Cells Including Cancer Stem Cells

#5480
20200197432
2020-06-25

Methods And Compositions For Controlling Cardiac Fibrosis And Remodeling

#5481
20200197320
2020-06-25

DRUG CARRIER AND DRUG DELIVERY SYSTEM THEREOF

#5482
20200196609
2020-06-25

Compositions and methods to control insect pests

#5483
20200190595
2020-06-18

KIT FOR EVALUATING GENE MUTATION RELATED TO MYELOPROLIFERATIVE TUMOR

#5484
20200190558
2020-06-18

THREE MOLECULAR MARKERS, KITS AND APPLICATIONS FOR GLAUCOMA DIAGNOSIS

#5485
20200190542
2020-06-18

Methods and compositions for RNA-directed target DNA modification and for RNA-directed modulation of transcription

#5486
20200190541
2020-06-18

METHODS FOR REDUCING DNA-INDUCED CYTOTOXICITY AND ENHANCING GENE EDITING IN PRIMARY CELLS

#5487
20200190540
2020-06-18

GENETIC TARGETING IN NON-CONVENTIONAL YEAST USING AN RNA-GUIDED ENDONUCLEASE

#5488
20200190522
2020-06-18

COMPOUNDS AND METHODS FOR MODULATING TMPRSS6 EXPRESSION

#5489
20200190519
2020-06-18

Brush polymer-assisted compaction of oligonucleotides

#5490
20200190518
2020-06-18

Peptide, complex of peptide and siRNA, and methods of use thereof

#5491
20200190517
2020-06-18

Organic compositions to treat EPAS1-related diseases

#5492
20200190516
2020-06-18

EXON SKIPPING OLIGOMER CONJUGATES FOR MUSCULAR DYSTROPY

#5493
20200190515
2020-06-18

Oligonucleotide compositions and methods of use thereof

#5494
20200190514
2020-06-18

Nucleic acid suppressing expression of APCS

#5495
20200190513
2020-06-18

Methods and systems for analyzing guide RNA molecules

#5496
20200190512
2020-06-18

Nucleic acid molecules and their use in therapy

#5497
20200190511
2020-06-18

MICRO-RNA FAMILY THAT MODULATES FIBROSIS AND USES THEREOF

#5498
20200190472
2020-06-18

Agents and methods to elicit anti-tumor immune response

#5499
20200190211
2020-06-18

Targeting gene amplification in cancer using triplex formation as a therapeutic strategy

#5500
20200188469
2020-06-18

COMPOUNDS AND METHODS FOR INHIBITING CDK5 ALLEVIATE CARDIAC PHENOTYPES IN TIMOTHY SYNDROME AND RELATED CONDITIONS

#5501
20200188456
2020-06-18

Anellovirus compositions and methods of use

#5502
20200188424
2020-06-18

Compositions and methods for the treatment of fibrotic diseases

#5503
20200188422
2020-06-18

Inhibition of expansion and function of pathogenic age-associated B cells and use for the prevention and treatment of autoimmune disease

#5504
20200182860
2020-06-11

METHODS FOR IDENTIFYING THERAPEUTIC AGENTS WHICH INTERACT WITH STK24

#5505
20200181708
2020-06-11

MICRO-RNAS THAT MODULATE LYMPHANGIOGENESIS AND INFLAMMATORY PATHWAYS IN LYMPHATIC VESSEL CELLS

#5506
20200181650
2020-06-11

Primary cell gene editing

#5507
20200181639
2020-06-11

RNAI APPROACH FOR CROP PEST PROTECTION

#5508
20200181634
2020-06-11

ENHANCEMENT OF PLANT YIELD VIGOR AND STRESS TOLERANCE

#5509
20200181626
2020-06-11

Compositions of self-reporting transposon (SRT) constructs and methods for mapping transposon insertions

#5510
20200181624
2020-06-11

Chimeric transcription factor variants with augmented sensitivity to drug ligand induction of transgene expression in mammalian cells

#5511
20200181622
2020-06-11

Antisense oligonucleotides (ODN) against SMAD7 and uses thereof in medical field

#5512
20200181619
2020-06-11

Aptazyme-embedded guide RNAs for use with CRISPR-Cas9 in genome editing and transcriptional activation

#5513
20200181616
2020-06-11

Antisense oligonucleotides for the treatment of eye disease

#5514
20200181615
2020-06-11

Anti-inflammatory treatment via inhibition of endothelial cell kinesin light chain 1, variant 1 (KLC1C)

#5515
20200181614
2020-06-11

COMPOSITIONS AND METHODS FOR INHIBITING EXPRESSION OF THE ALAS1 GENE

#5516
20200181613
2020-06-11

COMPOSITIONS AND METHODS FOR MODULATION OF SMN2 SPLICING

#5517
20200181612
2020-06-11

Method of treating cancer by antisense oligonucleotides targeting PRDM15

#5518
20200181610
2020-06-11

Gene-regulating compositions and methods for improved immunotherapy

#5519
20200179522
2020-06-11

NANOSTRUCTURES FOR PENETRATING DEEP INTO CANCER TISSUES

#5520
20200179490
2020-06-11

Collagen-mimetic peptide mediated delivery of nucleic acid carriers for efficient delivery from collagen

#5521
20200179435
2020-06-11

Modulators of FOXP3 expression

#5522
20200178566
2020-06-11

Systems and methods for the control of acute hepatopancreatic necrosis disease

#5523
20200172984
2020-06-04

Colorectal cancer detection kit or device, and detection method

#5524
20200172934
2020-06-04

CRISPR-CAS system for a yeast host cell

#5525
20200172931
2020-06-04

Methods and compositions for evolving base editors using phage-assisted continuous evolution (PACE)

#5526
20200172922
2020-06-04

Methods for genetic control of insect infestations in plants and compositions thereof

#5527
20200172904
2020-06-04

METHODS OF MODULATING PROTEIN EXPRESSION FROM THE MENA-RIBONUCLEOPROTEIN COMPLEX IN CELLS

#5528
20200172903
2020-06-04

ENA ANTISENSE OLIGONUCLEOTIDE FOR INHIBITION OF alpha-SYNUCLEIN EXPRESSION

#5529
20200172902
2020-06-04

Compositions and methods for detecting and treating insulin resistance

#5530
20200172886
2020-06-04

CasZ compositions and methods of use

#5531
20200172472
2020-06-04

Lipids for use in lipid nanoparticle formulations

#5532
20200171110
2020-06-04

HSV VECTOR WITH REDUCED NEUROTOXICITY

#5533
20200171071
2020-06-04

Modulation of the notch signaling pathway for treatment of respiratory disorders

#5534
20200171069
2020-06-04

Methods for treating hepatitis B infection

#5535
20200171067
2020-06-04

Cancer Treatment Based on Delivery of Oligoes via Gap Junctions from Human Mesenchymal Stem Cells (hMSC)

#5536
20200165674
2020-05-28

COTL1 protein involved in maintaining homeostasis of hematopoietic stem cell, and use thereof

#5537
20200165639
2020-05-28

Methods and compositions for preparing tagatose from fructose

#5538
20200165637
2020-05-28

CRISPR-CAS system for a lipolytic yeast host cell

#5539
20200165636
2020-05-28

Systems and methods for targeted integration and genome editing and detection thereof using integrated priming sites

#5540
20200165634
2020-05-28

Primary cell gene editing

#5541
20200165630
2020-05-28

Compositions for the treatment of disease

#5542
20200165628
2020-05-28

TISSUE SELECTIVE TRANSGENE EXPRESSION

#5543
20200165627
2020-05-28

Compositions and methods for controlling

#5544
20200165615
2020-05-28

RNAi-MEDIATED INHIBITION OF HIF1A FOR TREATMENT OF OCULAR ANGIOGENESIS

#5545
20200165611
2020-05-28

Therapeutic splice-switching oligonucleotides

#5546
20200165610
2020-05-28

Antisense oligonucleotide controlling expression amount of TDP-43 and use thereof

#5547
20200165609
2020-05-28

METHODS OF IDENTIFYING MIRNAS AND APPLICATIONS THEREOF

#5548
20200165608
2020-05-28

INHIBITION OF VASCULAR ENDOTHELIAL CELL-MEDIATED PHAGOCYTIC PROCESSES FOR TREATMENT OF DEMYELINATING CONDITIONS

#5549
20200165607
2020-05-28

COMPOSITION AND METHOD OF USING MIR-302 PRECURSORS AS ANTI-CANCER DRUGS FOR TREATING HUMAN LUNG CANCER

#5550
20200165606
2020-05-28

Modified Oligonucleotides for Treatment of Polycystic Kidney Disease

#5551
20200165605
2020-05-28

Mammalian cells for producing a secreted protein

#5552
20200165604
2020-05-28

LncRNAs for therapy and diagnosis of cardiac hypertrophy

#5553
20200164020
2020-05-28

PUM 1 protein as target for virus inhibition

#5554
20200163941
2020-05-28

Method for treating neurodegenerative diseases

#5555
20200157627
2020-05-21

Presymptomatic micro RNA targets for treatment of neurodegeneration pathology

#5556
20200157563
2020-05-21

METHODS OF PRODUCING HUMAN CANCER CELL MODELS AND METHODS OF USE

#5557
20200157554
2020-05-21

PLANT GENOME MODIFICATION USING GUIDE RNA/CAS ENDONUCLEASE SYSTEMS AND METHODS OF USE

#5558
20200157548
2020-05-21

COMPOSITIONS AND METHODS FOR ENHANCED INTESTINAL ABSORPTION OF CONJUGATED OLIGOMERIC COMPOUNDS

#5559
20200157541
2020-05-21

EXOSOME LOADED THERAPEUTICS FOR THE TREATMENT OF NON-ALCOHOLIC STEATOHEPATITIS, DIABETES MELLITUS TYPE 1 AND TYPE 2, ATHEROSCLEROTIC CARDIOVASCULAR DISEASE, AND ALPHA 1 ANTITRYPSIN DEFICIENCY

#5560
20200157540
2020-05-21

RNA interference delivery formulation and methods for malignant tumors

#5561
20200157539
2020-05-21

Use of therapeutic agents

#5562
20200157538
2020-05-21

SMN2 element 1 antisense compositions and methods and uses thereof

#5563
20200157537
2020-05-21

Modulating RNA Interactions with Polycomb Repressive Complex 1 (PRC1)

#5564
20200157536
2020-05-21

Antisense therapies for treating cancer

#5565
20200157535
2020-05-21

METHODS AND COMPOSITIONS FOR MODULATING ALPHA-1-ANTITRYPSIN EXPRESSION

#5566
20200157225
2020-05-21

INHIBITOR OF SUV39H1 HISTONE METHYLTRANSFERASE FOR USE IN CANCER COMBINATION THERAPY

#5567
20200155731
2020-05-21

DEVICE AND METHOD FOR PROMOTING RAPID STRUT COVERAGE AND VASCULAR ENDOTHELIAL COVERAGE

#5568
20200155703
2020-05-21

Therapeutic Membrane Vesicles

#5569
20200155657
2020-05-21

Fungal immunogens and related materials and methods

#5570
20200155624
2020-05-21

Compositions and methods of treating Huntington's disease

#5571
20200155594
2020-05-21

Hornerin: a novel non-VEGF mediated angiogenic protein expressed in both human and mouse angiogenic endothelial cells and human pancreatic cancer cells

#5572
20200149070
2020-05-14

METHODS AND COMPOSITIONS FOR GENOME EDITING

#5573
20200149051
2020-05-14

Use of potassium channel inhibitor for treating depression

#5574
20200149045
2020-05-14

Modulatory polynucleotides

#5575
20200149044
2020-05-14

Control of insect infestation

#5576
20200149043
2020-05-14

RNA modulating oligonucleotides with improved characteristics for the treatment of neuromuscular disorders

#5577
20200149042
2020-05-14

MODULATING BIOMARKERS TO INCREASE TUMOR IMMUNITY AND IMPROVE THE EFFICACY OF CANCER IMMUNOTHERAPY

#5578
20200149041
2020-05-14

Gene Therapy Drug for Granular Corneal Degeneration

#5579
20200149040
2020-05-14

Antisense nucleic acids

#5580
20200149021
2020-05-14

System and method for genome editing

#5581
20200148789
2020-05-14

Method to reduce pulmonary arterial hypertension by administering inhibitors of nicotinamide phosphoribotransferase

#5582
20200148749
2020-05-14

Antibodies and processes for preparing the same

#5583
20200147156
2020-05-14

Oncolytic viral vectors and uses thereof

#5584
20200147142
2020-05-14

COMPOSITIONS AND METHODS FOR ENHANCING THE THERAPEUTIC POTENTIAL OF STEM CELLS

#5585
20200147133
2020-05-14

Combination Therapy of Acellular Pro-Tolerogenic and Pro-Inflammatory Preparations for Modulating the Immune System

#5586
20200147123
2020-05-14

Nucleic acid molecule for reduction of PAPD5 and PAPD7 mRNA for treating hepatitis B infection

#5587
20200147122
2020-05-14

Nucleoporins as drug targets for anti-proliferative therapeutics

#5588
20200147119
2020-05-14

Oligonucleotide analogues targeting human LMNA

#5589
20200147118
2020-05-14

COMPOSITIONS AND METHODS FOR DETECTION, RISK ASSESSMENT AND TREATMENT OF DIABETES, OBESITY, AND INFLAMMATION

#5590
20200147046
2020-05-14

Methods and compositions for the treatment of retinopathy and other ocular diseases

#5591
20200147045
2020-05-14

Methods and compositions for the treatment of retinopathy and other ocular diseases

#5592
20200146269
2020-05-14

METHODS AND COMPOSITIONS FOR MODULATING INNATE LYMPHOID CELL PATHOGENIC EFFECTORS

#5593
20200141839
2020-05-07

Methods, compositions, and devices involving pseudoknot formation

#5594
20200140887
2020-05-07

Viral delivery of RNA utilizing self-cleaving ribozymes and CRISPR-based applications thereof

#5595
20200140884
2020-05-07

DOWN-REGULATING GENE EXPRESSION IN INSECT PLANTS

#5596
20200140876
2020-05-07

Whole seed specific promoter

#5597
20200140870
2020-05-07

Fidgetin-like 2 as a target to enhance wound healing

#5598
20200140866
2020-05-07

Angiopoietin-like 3 (ANGPTL3) iRNA compositions and methods of use thereof

#5599
20200140863
2020-05-07

Identification of a JAK2 mutation in polycythemia vera

#5600
20200140862
2020-05-07

Therapeutic agent for a lung disease and/or method for screening for the same

#5601
20200140861
2020-05-07

Long non-coding RNA in cancer

#5602
20200140860
2020-05-07

IncRNAs GADLOR 1 and 2 for use in treating and preventing cardiac remodelling

#5603
20200140859
2020-05-07

COMPOUNDS THAT TARGET MYC microRNA RESPONSIVE ELEMENTS FOR THE TREATMENT OF MYC-ASSOCIATED CANCER

#5604
20200140857
2020-05-07

Methods and means for treating DNA repeat instability associated genetic disorders

#5605
20200140380
2020-05-07

METHOD OF SYNTHESIS OF AN IONIZABLE CATIONIC LIPID

#5606
20200140378
2020-05-07

Cationic sulfonamide amino lipids and amphiphilic zwitterionic amino lipids

#5607
20200138955
2020-05-07

Lipid compositions

#5608
20200138849
2020-05-07

Reagents for treatment of oculopharyngeal muscular dystrophy (OPMD) and use thereof

#5609
20200138847
2020-05-07

Myostatin iRNA compositions and methods of use thereof

#5610
20200138846
2020-05-07

Enzymatic replacement therapy and antisense therapy for Pompe disease

#5611
20200131555
2020-04-30

INCORPORATION OF UNNATURAL NUCLEOTIDES AND METHODS THEREOF

#5612
20200131536
2020-04-30

Method for identifying DNA base editing by means of cytosine deaminase

#5613
20200131513
2020-04-30

Factor XII (hageman factor) (F12), kallikrein B, plasma (fletcher factor) 1 (KLKB1), and kininogen 1 (KNG1) iRNA compositions and methods of use thereof

#5614
20200131234
2020-04-30

Micropeptides and use of same for modulating gene expression

#5615
20200129445
2020-04-30

Lipid nanoparticle formulation

#5616
20200128832
2020-04-30

ALTERING MICROBIAL POPULATIONS & MODIFYING MICROBIOTA

#5617
20200128802
2020-04-30

Recombinant vector comprising ERT2 fused to CAS9

#5618
20200123575
2020-04-23

Molecular system for cancer biology

#5619
20200123574
2020-04-23

Compositions and methods of treating amyotrophic lateral sclerosis (ALS)

#5620
20200123568
2020-04-23

ANTI-REFLECTIVE ARTICLES WITH NANOSILICA-BASED COATINGS

#5621
20200123546
2020-04-23

ANTISENSE NUCLEIC ACID FOR TREATING AMYOTROPHY

#5622
20200123545
2020-04-23

Treatment strategies against anthrax by interfering with critical host factors

#5623
20200123544
2020-04-23

GENE THERAPY TARGETING THE NEONATAL FORM OF NAV1.5 FOR TREATING CANCER

#5624
20200123543
2020-04-23

Modified oligonucleotides targeting SNPs

#5625
20200123542
2020-04-23

RNA COMPOSITIONS FOR GENOME EDITING

#5626
20200123261
2020-04-23

NUCLEIC ACID-POLYPEPTIDE COMPOSITIONS AND USES THEREOF

#5627
20200123245
2020-04-23

Methods for reducing post-operative cognitive dysfunction (POCD)

#5628
20200121746
2020-04-23

ADENO-ASSOCIATED VIRUS VIRIONS WITH VARIANT CAPSIDS AND METHODS OF USE THEREOF

#5629
20200121727
2020-04-23

Methods and compositions for treating skeletal muscular dystrophy

#5630
20200121710
2020-04-23

Double-stranded nucleic acid molecule, DNA, vector, cancer cell growth inhibitor, cancer cell migration inhibitor, and drug

#5631
20200116726
2020-04-16

PANCREATIC CANCER TARGETS AND USES THEREOF

#5632
20200115711
2020-04-16

Modulation of angiopoietin-like 3 expression

#5633
20200115710
2020-04-16

HETERO DOUBLE-STRANDED antimiR

#5634
20200115709
2020-04-16

Functionally-modified oligonucleotides and subunits thereof

#5635
20200115687
2020-04-16

Systems, methods and compositions for sequence manipulation with optimized functional CRISPR-Cas systems

#5636
20200115411
2020-04-16

Antisense nucleic acids

#5637
20200114019
2020-04-16

PH-sensitive lipid nanoparticles for encapsulation of anticancer drugs and microRNA and use thereof

#5638
20200113928
2020-04-16

P-ethoxy nucleic acids for liposomal formulation

#5639
20200113927
2020-04-16

LACTATE DEHYDROGENASE A (LDHA) iRNA COMPOSITIONS AND METHODS OF USE THEREOF

#5640
20200113832
2020-04-16

NOVEL LIPID FORMULATIONS FOR NUCLEIC ACID DELIVERY

#5641
20200109403
2020-04-09

In vivo delivery of oligonucleotides

#5642
20200109402
2020-04-09

Methods of reducing expression of x-inactivation escapee genes and autosomal genes

#5643
20200109401
2020-04-09

Variant RNAi

#5644
20200109400
2020-04-09

Splicing-dependent transcriptional gene silencing or activation

#5645
20200109399
2020-04-09

Vectors and compositions for treating hemoglobinopathies

#5646
20200109162
2020-04-09

Antisense nucleic acids

#5647
20200108109
2020-04-09

Methods for the Delivery of Therapeutic Agents to Donor Organs

#5648
20200102574
2020-04-02

Functional Nucleic Acid Protective Vector Based On DNA Hydrogel, Preparation Method and Application Thereof

#5649
20200102566
2020-04-02

Engineered shell proteins for microcompartment shell electron transfer and catalysis

#5650
20200102563
2020-04-02

EXOSOME LOADED THERAPEUTICS FOR TREATING SICKLE CELL DISEASE

#5651
20200102562
2020-04-02

Beta-TUBULIN, Beta-TUBULIN GENE AND APPLICATION OF GENE SEGMENT THEREOF

#5652
20200102561
2020-04-02

Compositions and methods for the treatment of hemoglobinopathies

#5653
20200102560
2020-04-02

POLYNUCLEOTIDE AGENTS TARGETING SERPINC1 (AT3) AND METHODS OF USE THEREOF

#5654
20200102559
2020-04-02

Methods for controlling seizures by manipulating the levels of microRNA-211 (miR-211) in the brain

#5655
20200102545
2020-04-02

DELIVERY OF PACKAGED RNA TO MAMMALIAN CELLS

#5656
20200102385
2020-04-02

Compositions and methods for treating cancer with anti-ROR1 immunotherapy

#5657
20200102382
2020-04-02

Compositions And Methods For Treating Cancer

#5658
20200102361
2020-04-02

VIRAL EXPRESSION CONSTRUCT COMPRISING A FIBROBLAST GROWTH FACTOR 21 (FGF21) CODING SEQUENCE

#5659
20200102343
2020-04-02

Antisense nucleic acids

#5660
20200101016
2020-04-02

COMPOSITIONS AND METHODS FOR PRODUCING EXOSOME LOADED THERAPEUTICS FOR TREATING CARDIOVASCULAR DISEASE

#5661
20200095590
2020-03-26

TRANSCRIPTION SYSTEM

#5662
20200095585
2020-03-26

Methods for Producing Enteroendocrine Cells That Make and Secrete Insulin

#5663
20200095584
2020-03-26

Methods for multiplexing recombinase polymerase amplification

#5664
20200095583
2020-03-26

Methods and compositions for managing vascular conditions

#5665
20200095582
2020-03-26

BCL11A guide delivery

#5666
20200095581
2020-03-26

MODULATION OF APOLIPOPROTEIN C-III (APOCIII) EXPRESSION IN LIPODYSTROPHY POPULATIONS

#5667
20200095580
2020-03-26

Products and compositions

#5668
20200095579
2020-03-26

MATERIALS AND METHODS FOR TREATMENT OF MEROSIN-DEFICIENT COGENITAL MUSCULAR DYSTROPHY (MDCMD) AND OTHER LAMININ, ALPHA 2 (LAMA2) GENE RELATED CONDITIONS OR DISORDERS

#5669
20200095578
2020-03-26

POLYNUCLEOTIDE AGENTS TARGETING COMPLEMENT COMPONENT C5 AND METHODS OF USE THEREOF

#5670
20200095553
2020-03-26

FORMULATION COMPRISING EXTRACELLULAR VESICLES, METHOD FOR PRODUCING THE SAME, AND USES THEREOF

#5671
20200093824
2020-03-26

ERBB3 Activators in Hearing Restoration

#5672
20200093793
2020-03-26

Methods and compositions for the treatment of retinopathy and other ocular diseases

#5673
20200093084
2020-03-26

Stable transformation of a population and a method of biocontainment using haploinsufficiency and underdominance principles

#5674
20200088733
2020-03-19

Biomarkers and methods for diagnosis of early stage pancreatic ductal adenocarcinoma

#5675
20200087665
2020-03-19

SYSTEMS

#5676
20200087664
2020-03-19

AAV treatment of Huntington's disease

#5677
20200087663
2020-03-19

O-methyl rich fully stabilized oligonucleotides

#5678
20200087662
2020-03-19

Inhibition of poly(A) binding protein and the treatment of pain

#5679
20200087661
2020-03-19

Compositions for modulating Ataxin 2 expression

#5680
20200087642
2020-03-19

METHODS AND COMPOSITIONS FOR MODIFYING A SINGLE STRANDED TARGET NUCLEIC ACID

#5681
20200085967
2020-03-19

TARGETING PAX2 FOR THE TREATMENT OF BREAST CANCER

#5682
20200085947
2020-03-19

Vista modulators for diagnosis and treatment of cancer

#5683
20200085944
2020-03-19

RNA VACCINE AND IMMUNE CHECKPOINT INHIBITORS FOR COMBINED ANTICANCER THERAPY

#5684
20200085853
2020-03-19

TARGETING NR3B1 FOR TREATMENT OF NASH

#5685
20200085802
2020-03-19

Method for prediction of susceptibility to sorafenib treatment by using SULF2 gene, and composition for treatment of cancer comprising SULF2 inhibitor

#5686
20200085758
2020-03-19

CO-DELIVERY OF NUCLEIC ACIDS FOR SIMULTANEOUS SUPPRESSION AND EXPRESSION OF TARGET GENES

#5687
20200085742
2020-03-19

NANOSCALE CARRIERS FOR THE DELIVERY OR CO-DELIVERY OF CHEMOTHERAPEUTICS, NUCLEIC ACIDS AND PHOTOSENSITIZERS

#5688
20200085066
2020-03-19

ALTERING MICROBIAL POPULATIONS & MODIFYING MICROBIOTA

#5689
20200080156
2020-03-12

PROSTATIC CANCER MARKER, PLXNA1, AND APPLICATION THEREOF

#5690
20200080154
2020-03-12

METHODS OF DIAGNOSING AND TREATING ALZHEIMER'S DISEASE

#5691
20200080126
2020-03-12

Method for selective translation of desired proteins in the presence of a specified nucleic acid ligand

#5692
20200080113
2020-03-12

Methods and compositions for RNA-directed target DNA modification and for RNA-directed modulation of transcription

#5693
20200080112
2020-03-12

Crispr enzymes and systems

#5694
20200080108
2020-03-12

CRISPR/CAS9-BASED COMPOSITIONS AND METHODS FOR TREATING RETINAL DEGENERATIONS

#5695
20200080105
2020-03-12

RNAi strategies for control of whitefly

#5696
20200080097
2020-03-12

SIMULTANEOUS GENE EDITING AND HAPLOID INDUCTION

#5697
20200080094
2020-03-12

CRISPR-CAS COMPONENT SYSTEMS, METHODS AND COMPOSITIONS FOR SEQUENCE MANIPULATION

#5698
20200080088
2020-03-12

APOLIPOPROTEIN C3 (APOC3) iRNA COMPOSITIONS AND METHODS OF USE THEREOF

#5699
20200080087
2020-03-12

Twist signaling inhibitor compositions and methods of using the same

#5700
20200080086
2020-03-12

Cationic lipid