ClassID:

109048

C12N15/113 - page 24 - CPC Classification

Classification description:

Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor; Recombinant DNA-technology; DNA or RNA fragments; Modified forms thereof Non-coding nucleic acids modulating the expression of genes, e.g. antisense oligonucleotides

Recent Application in this class:
#6901
20180325992
2018-11-15

MODULATION OF AXON DEGENERATION

#6902
20180325937
2018-11-15

Modulation of ciliogenesis

#6903
20180325820
2018-11-15

BIOCOMPATIBLE WATER-SOLUBLE POLYMERS INCLUDING SULFOXIDE FUNCTIONALITY

#6904
20180320202
2018-11-08

Compositions and methods for modifying a target nucleic acid

#6905
20180320198
2018-11-08

Methods and compositions for integration defective lentiviral vectors

#6906
20180320187
2018-11-08

Toxic RNAi active seed sequences for killing cancer cells

#6907
20180320182
2018-11-08

Methods and Compositions for Selecting siRNA of Improved Functionality

#6908
20180320181
2018-11-08

Chimeric double-stranded nucleic acid

#6909
20180320180
2018-11-08

AGE-RELATED MACULAR DEGENERATION TREATMENT

#6910
20180320179
2018-11-08

LANOSTEROL 14-ALPHA DEMETHYLASE (CYP51) NUCLEIC ACID MOLECULES THAT CONTROL PATHOGENS

#6911
20180320178
2018-11-08

Stem cell with suppressed SOCS and improved immunosuppressive ability and use thereof

#6912
20180320177
2018-11-08

COMPOSITIONS AND METHODS FOR THE TREATMENT OF LIVER FIBROSIS

#6913
20180320176
2018-11-08

INTRATHECAL DELIVERY OF NUCLEIC ACID SEQUENCES ENCODING ABCD1 FOR TREATMENT OF ADRENOMYELONEUROPATHY

#6914
20180320175
2018-11-08

RNA interactome of polycomb repressive complex 1 (PRC1)

#6915
20180318448
2018-11-08

Method for determining presence or absence of suffering from malignant lymphoma or leukemia, and agent for treatment and/or prevention of leukemia

#6916
20180318428
2018-11-08

POLYAMINATED POLYGLUTAMIC ACID-CONTAINING COMPOUNDS AND USES THEREOF FOR DELIVERING OLIGONUCLEOTIDES

#6917
20180318389
2018-11-08

NMDAR antagonists for the treatment of diseases associated with angiogenesis

#6918
20180318331
2018-11-08

Method for treating schizophrenia

#6919
20180318330
2018-11-08

Compounds and methods for modulating C90RF72

#6920
20180318216
2018-11-08

DEFORMABLE NANO-SCALE VEHICLES (DNVS) FOR TRANS-BLOOD BRAIN BARRIER, TRANS-MUCOSAL, AND TRANSDERMAL DRUG DELIVERY

#6921
20180314794
2018-11-01

Mantle phenotype detection in palm

#6922
20180313841
2018-11-01

Ovary Tumor Markers And Methods Of Use Thereof

#6923
20180312929
2018-11-01

Methods and compositions related to T-cell activity

#6924
20180312876
2018-11-01

Methods and compositions for RNA-directed target DNA modification and for RNA-directed modulation of transcription

#6925
20180312875
2018-11-01

Methods and compositions for RNA-directed target DNA modification and for RNA-directed modulation of transcription

#6926
20180312874
2018-11-01

Methods and compositions for RNA-directed target DNA modification and for RNA-directed modulation of transcription

#6927
20180312867
2018-11-01

Identification and use of target genes for control of plant parasitic nematodes

#6928
20180312855
2018-11-01

ALGAL PROMOTERS

#6929
20180312847
2018-11-01

Methods of treatment using antisense oligomers and conjugates targeting PCSK9

#6930
20180312846
2018-11-01

Manufacture of antisense oligomers and conjugates targeting PCSK9

#6931
20180312841
2018-11-01

RIG-I ligands and methods for producing them

#6932
20180312840
2018-11-01

COMPOUNDS AND METHODS FOR MODULATING APOLIPOPROTEIN C-III EXPRESSION FOR IMPROVING A DIABETIC PROFILE

#6933
20180312839
2018-11-01

METHODS AND COMPOSITIONS FOR INCREASING SMN EXPRESSION

#6934
20180312838
2018-11-01

MODULATION OF MICRORNA 184 TO TREAT PATHOLOGICAL LYMPHANGIOGENESIS

#6935
20180312837
2018-11-01

Compounds and compositions including phosphorothioated oligodeoxynucleotide, and methods of use thereof

#6936
20180312827
2018-11-01

Engineered nucleic-acid targeting nucleic acids

#6937
20180312809
2018-11-01

Agents and methods to elicit anti-tumor immune response

#6938
20180312557
2018-11-01

Leg1 Protein, Leg1 Gene, and Uses and Drugs thereof

#6939
20180311193
2018-11-01

Method of treating delayed healing of a wound associated with diabetes

#6940
20180306796
2018-10-25

Methods and compositions relating to proteasome inhibitor resistance

#6941
20180305773
2018-10-25

CRISPR effector system based diagnostics for malaria detection

#6942
20180305716
2018-10-25

Methods and compositions for the activation of gamma-delta T-cells

#6943
20180305715
2018-10-25

Nucleic acid molecules containing spacers and methods of use thereof

#6944
20180305713
2018-10-25

PARENTAL RNAI SUPPRESSION OF CHROMATIN REMODELING GENES TO CONTROL COLEOPTERAN PESTS

#6945
20180305712
2018-10-25

Transgenic plant of the species with resistance to

#6946
20180305704
2018-10-25

CRISPR-CAS COMPONENT SYSTEMS, METHODS AND COMPOSITIONS FOR SEQUENCE MANIPULATION

#6947
20180305694
2018-10-25

PARENTAL RNAI SUPPRESSION OF HUNCHBACK GENE TO CONTROL HEMIPTERAN PESTS

#6948
20180305693
2018-10-25

Treatment of down syndrome gene related diseases by inhibition of natural antisense transcript to a down syndrome gene

#6949
20180305692
2018-10-25

Antisense oligonucleotides for the treatment of leber congenital amaurosis

#6950
20180305691
2018-10-25

MicroRNA Compounds and Methods for Modulating MIR-21 Activity

#6951
20180305690
2018-10-25

Targeting MicroRNAs for the Treatment of Fibrosis

#6952
20180305689
2018-10-25

SARNA COMPOSITIONS AND METHODS OF USE

#6953
20180305670
2018-10-25

Method and System for Monitoring Nutritional Uptake as a Function of Hydrogen Gas Levels

#6954
20180303957
2018-10-25

NUCLEIC ACID-LIPOPOLYMER COMPOSITIONS

#6955
20180303864
2018-10-25

POLYNUCLEOTIDES HAVING BIOREVERSIBLE GROUPS

#6956
20180298407
2018-10-18

METHODS AND COMPOSITIONS FOR RNA-DIRECTED TARGET DNA MODIFICATION AND FOR RNA-DIRECTED MODULATION OF TRANSCRIPTION

#6957
20180298406
2018-10-18

METHODS AND COMPOSITIONS FOR RNA-DIRECTED TARGET DNA MODIFICATION AND FOR RNA-DIRECTED MODULATION OF TRANSCRIPTION

#6958
20180298385
2018-10-18

Methods for Treatment of Alport Syndrome

#6959
20180298384
2018-10-18

COMPOSITIONS AND METHODS FOR MODULATING SMN GENE FAMILY EXPRESSION

#6960
20180298383
2018-10-18

Peptide oligonucleotide conjugates

#6961
20180298382
2018-10-18

Non-coding RNAs linked to immortality and associated methods and compositions

#6962
20180298381
2018-10-18

Chimeric decoy

#6963
20180298380
2018-10-18

Modified AAV constructs and uses thereof

#6964
20180297938
2018-10-18

Compounds for targeting drug delivery and enhancing siRNA activity

#6965
20180296644
2018-10-18

Method of treating cancer with compositions comprising IL-31

#6966
20180295817
2018-10-18

Methods of agent delivery into eggs and embryos of egg-producing aquatic animals for drug screening, agent toxicity assay and production of infertile fish

#6967
20180292416
2018-10-11

Methods for diagnosing Huntington's disease

#6968
20180291462
2018-10-11

Treatment targeting oncology and neurodegeneration

#6969
20180291453
2018-10-11

SELECTIVE REDUCTION OF ALLELIC VARIANTS

#6970
20180291429
2018-10-11

Oligonucleotide inhibitor of DNA polymerases

#6971
20180291381
2018-10-11

Interfering RNA molecules

#6972
20180291377
2018-10-11

Blood Brain Barrier Opening Agents and Uses Thereof

#6973
20180291376
2018-10-11

COMPOSITIONS AND METHODS FOR MODULATION OF SMN2 SPLICING

#6974
20180291375
2018-10-11

ETS factors regulate neural stem cell depletion and gliogenesis in Ras pathway glioma

#6975
20180291374
2018-10-11

INHIBITORS OF MICRORNAs miR-155, miR-103, miR-105 and miR-107 THAT REGULATE PRODUCTION OF ATRIAL NATRIURETIC PEPTIDE (ANP) AS THERAPEUTICS AND USES THEREOF

#6976
20180291373
2018-10-11

USE OF THERAPEUTIC AGENTS

#6977
20180291366
2018-10-11

Method for altering the functional state of mRNA allowing its selective and specific recognition

#6978
20180289835
2018-10-11

Micelle composition for nucleic acid delivery using temperature-sensitive polymer and method for producing same

#6979
20180289015
2018-10-11

METHODS OF PRESERVING THE BIOLOGICAL ACTIVITY OF RIBONUCLEIC ACIDS

#6980
20180288984
2018-10-11

Method of producing infertile fish and egg-producing aquatic animals and of delivering compounds into eggs and embryos

#6981
20180282785
2018-10-04

Treatment and diagnosis of immune disorders

#6982
20180282764
2018-10-04

Methods and compositions for RNA-directed target DNA modification and for RNA-directed modulation of transcription

#6983
20180282756
2018-10-04

PRE-MRNA PROCESSING FACTOR 19 (PRP19) NUCLEIC ACID MOLECULES TO CONTROL INSECT PESTS

#6984
20180282733
2018-10-04

Therapeutic agent for sarcopenia and metabolic diseases

#6985
20180282728
2018-10-04

ORGANIC COMPOSITIONS TO TREAT BETA-CATENIN-RELATED DISEASES

#6986
20180282727
2018-10-04

Plant-mediated silencing of a fatty acid and retinoid binding protein in

#6987
20180282726
2018-10-04

Bioactive renal cells

#6988
20180282725
2018-10-04

Lipid formulated compositions and methods for inhibiting expression of Serum Amyloid A gene

#6989
20180282724
2018-10-04

Use of single-stranded antisense oligonucleotide in prevention or treatment of genetic diseases involving a trinucleotide repeat expansion

#6990
20180282723
2018-10-04

Methods and compositions for the specific inhibition of antithrombin 3 (AT3) by double-stranded RNA

#6991
20180282692
2018-10-04

Engraftable cell-based immunotherapy for long-term delivery of therapeutic proteins

#6992
20180274041
2018-09-27

FALZ for use as a target for therapies to treat cancer

#6993
20180274035
2018-09-27

Method for diagnosing and treating cancer brain metastasis and drug delivery system for enabling passage through blood-brain barrier

#6994
20180273981
2018-09-27

METHODS AND COMPOSITIONS FOR RNA-DIRECTED TARGET DNA MODIFICATION AND FOR RNA-DIRECTED MODULATION OF TRANSCRIPTION

#6995
20180273979
2018-09-27

PROTECTED DNA TEMPLATES FOR GENE MODIFICATION AND INCREASED HOMOLOGOUS RECOMBINATION IN CELLS AND METHODS OF USE

#6996
20180273968
2018-09-27

ACC OX promoter identified by microarray analysis

#6997
20180273961
2018-09-27

A CRISPR/Cas9 SYSTEM FOR HIGH EFFICIENT SITE-DIRECTED ALTERING OF PLANT GENOMES

#6998
20180273955
2018-09-27

Sterol regulatory element binding protein (SREBP) chaperone (SCAP) iRNA compositions and methods of use thereof

#6999
20180273954
2018-09-27

Induced exon inclusion in spinal muscle atrophy

#7000
20180273953
2018-09-27

Compositions and methods for modulating apolipoprotein (a) expression

#7001
20180273952
2018-09-27

Compositions and methods for modulating apolipoprotein C-III expression

#7002
20180273951
2018-09-27

Methods for modulating KLHL1 levels, methods for modulating current activity in T-type calcium channels, molecules therefor, and methods for identifying molecules therefor

#7003
20180273950
2018-09-27

Methods and compositions for the production of siRNAs

#7004
20180273949
2018-09-27

MODULATION OF TRANSTHYRETIN EXPRESSION

#7005
20180273948
2018-09-27

RNAi CONJUGATES, PARTICLES AND FORMULATIONS THEREOF

#7006
20180273947
2018-09-27

Programmed cell death 1 ligand 1 (PD-L1) iRNA compositions and methods of use thereof

#7007
20180273946
2018-09-27

MODULATION OF TRANSTHYRETIN EXPRESSION

#7008
20180273945
2018-09-27

Compositions and their uses directed to huntingtin

#7009
20180273944
2018-09-27

Oligonucleotide-based inhibitors comprising locked nucleic acid motif

#7010
20180273943
2018-09-27

Modulation of SMN expression

#7011
20180273942
2018-09-27

Compounds and methods for modulation of DUX4

#7012
20180273941
2018-09-27

Short non-coding protein regulatory RNAs (sprRNAs) and methods of use

#7013
20180273938
2018-09-27

Genome editing enhancement

#7014
20180273937
2018-09-27

Methods and compositions for sequence specific antimicrobials

#7015
20180273935
2018-09-27

Methods and compositions for generating CRISPR/Cas guide RNAs

#7016
20180273922
2018-09-27

Methods and compositions for modifying a single stranded target nucleic acid

#7017
20180273908
2018-09-27

Methods and compositions related to increased influenza virus production

#7018
20180273618
2018-09-27

Combination therapy for treatment of disease

#7019
20180273609
2018-09-27

Materials and methods for treatment of hemoglobinopathies

#7020
20180273577
2018-09-27

MODULATORS OF KRAS EXPRESSION

#7021
20180271893
2018-09-27

Methods for treating progeroid laminopathies using oligonucleotide analogues targeting human LMNA

#7022
20180271069
2018-09-27

Generation and correction of a humanized mouse model with a deletion of dystrophin exon 44

#7023
20180265890
2018-09-20

EFFICIENT AND SAFE TRANSPOSON INTEGRATION SYSTEM AND USE THEREOF

#7024
20180265888
2018-09-20

P0 gene silencing constructs and use

#7025
20180265871
2018-09-20

RIBOSOMAL NUCLEIC ACID MOLECULES TO CONTROL INSECT PESTS

#7026
20180265870
2018-09-20

AGENTS USEFUL IN TREATING FACIOSCAPULOHUMERAL MUSCULAR DYSTROPHY

#7027
20180265869
2018-09-20

Short interfering nucleic acid (siNA) molecules containing a 2′ internucleoside linkage (3dT)

#7028
20180265868
2018-09-20

METHODS AND COMPOSITIONS COMPRISING APSE KNOTS

#7029
20180265867
2018-09-20

NUCLEIC ACID MOLECULES WITH ENHANCED ACTIVITY

#7030
20180265866
2018-09-20

Antisense nucleic acids

#7031
20180265865
2018-09-20

RAAV-BASED COMPOSITIONS AND METHODS

#7032
20180265591
2018-09-20

METHODS AND COMPOSITIONS FOR DIAGNOSING AND TREATING DISEASES

#7033
20180265559
2018-09-20

Polypeptides, nucleic acids and uses thereof

#7034
20180264141
2018-09-20

Method effective to modulate expression of T-box protein 4 (Tbx4) for reducing progression of lung fibrosis after a lung injury

#7035
20180264140
2018-09-20

Motor neuron-specific expression vectors

#7036
20180259502
2018-09-13

Pharmaceutical composition for treating or preventing obesity

#7037
20180258430
2018-09-13

Compositions and Methods for Inhibiting Gene Expression of Alpha-1 AntiTrypsin

#7038
20180258429
2018-09-13

SARNA COMPOSITIONS AND METHODS OF USE

#7039
20180258428
2018-09-13

METHODS AND COMPOSITIONS FOR THE TREATMENT OF A METABOLIC DISORDER

#7040
20180258427
2018-09-13

Modified iRNA agents

#7041
20180258426
2018-09-13

Compounds for inducing anti-tumor immunity and methods thereof

#7042
20180258425
2018-09-13

Compositions and methods for modulating Ataxin 3 expression

#7043
20180258418
2018-09-13

METHOD OF IDENTIFYING GENOME-WIDE OFF-TARGET SITES OF BASE EDITORS BY DETECTING SINGLE STRAND BREAKS IN GENOMIC DNA

#7044
20180258417
2018-09-13

Rapid characterization of Cas endonuclease systems, PAM sequences and guide RNA elements

#7045
20180256749
2018-09-13

Compositions and methods for modulating FMR1 expression

#7046
20180256724
2018-09-13

Hydrogels for delivery of therapeutic compounds

#7047
20180256629
2018-09-13

Methods and compositions for modulating apolipoprotein (a) expression

#7048
20180256628
2018-09-13

Methods for therapeutic administration of messenger ribonucleic acid drugs

#7049
20180255751
2018-09-13

Delivery, use and therapeutic applications of the CRISPR-cas systems and compositions for modeling mutations in leukocytes

#7050
20180251852
2018-09-06

MUTANT CALRETICULIN FOR THE DIAGNOSIS OF MYELOID MALIGNANCIES

#7051
20180251795
2018-09-06

METHODS AND COMPOSITIONS FOR RNA-DIRECTED TARGET DNA MODIFICATION AND FOR RNA-DIRECTED MODULATION OF TRANSCRIPTION

#7052
20180251794
2018-09-06

METHODS AND COMPOSITIONS FOR RNA-DIRECTED TARGET DNA MODIFICATION AND FOR RNA-DIRECTED MODULATION OF TRANSCRIPTION

#7053
20180251793
2018-09-06

METHODS AND COMPOSITIONS FOR RNA-DIRECTED TARGET DNA MODIFICATION AND FOR RNA-DIRECTED MODULATION OF TRANSCRIPTION

#7054
20180251792
2018-09-06

Systems and methods for one-shot guide RNA (ogRNA) targeting of endogenous and source DNA

#7055
20180251791
2018-09-06

METHODS AND COMPOSITIONS FOR RNA-DIRECTED TARGET DNA MODIFICATION AND FOR RNA-DIRECTED MODULATION OF TRANSCRIPTION

#7056
20180251788
2018-09-06

Engineered nucleic acid-targeting nucleic acids

#7057
20180251779
2018-09-06

COPI COATOMER BETA SUBUNIT NUCLEIC ACID MOLECULES THAT CONFER RESISTANCE TO COLEOPTERAN AND HEMIPTERAN PESTS

#7058
20180251775
2018-09-06

Increasing plant oil content by altering a negative regulator of acetyl-coa carboxylase

#7059
20180251768
2018-09-06

Antisense oligonucleotide compositions

#7060
20180251766
2018-09-06

Targeting microRNAs for metabolic disorders

#7061
20180251764
2018-09-06

Oligonucleotide conjugates

#7062
20180251763
2018-09-06

Compositions and Methods for Inducing Senescence in Cancer Cells

#7063
20180251762
2018-09-06

Use of trinucleotide repeat RNAs to treat cancer

#7064
20180251761
2018-09-06

Oligomeric compounds comprising bicyclic nucleotides and uses thereof

#7065
20180251760
2018-09-06

Antisense nucleic acid for treating amyotrophy

#7066
20180251759
2018-09-06

Amino acid-modified nucleic acid and utilization thereof

#7067
20180251735
2018-09-06

Compositions and methods for differentiation of human pluripotent stem cells into desired cell types

#7068
20180251728
2018-09-06

Androgenetic haploid embryonic stem cell (AG-HAESC), and preparation method and use thereof

#7069
20180251533
2018-09-06

METHODS AND COMPOSITIONS FOR MODULATING MONOCYTE POPULATIONS AND RELATED USES THEREOF

#7070
20180251502
2018-09-06

COLON DISEASE TARGETS AND USES THEREOF

#7071
20180251485
2018-09-06

PYRAZOLOTRIAZOLYL NUCLEOSIDE ANALOGUES AND OLIGONUCLEOTIDES COMPRISING THEM

#7072
20180250424
2018-09-06

COMPOSITIONS AND METHODS FOR PROMOTING HOMOLOGY DIRECTED REPAIR

#7073
20180250410
2018-09-06

MODIFIED POLY (BETA-AMINO ESTER)S FOR DRUG DELIVERY

#7074
20180250409
2018-09-06

Pharmaceutical composition containing anionic drug, and preparation method therefor

#7075
20180250325
2018-09-06

MIR-19 MODULATORS AND USES THEREOF

#7076
20180245152
2018-08-30

Methods for detection of RNase activity

#7077
20180245137
2018-08-30

Methods and compositions for determining pH

#7078
20180245101
2018-08-30

METHODS AND COMPOSITIONS FOR RNA-DIRECTED TARGET DNA MODIFICATION AND FOR RNA-DIRECTED MODULATION OF TRANSCRIPTION

#7079
20180245100
2018-08-30

METHODS AND COMPOSITIONS FOR RNA-DIRECTED TARGET DNA MODIFICATION AND FOR RNA-DIRECTED MODULATION OF TRANSCRIPTION

#7080
20180245099
2018-08-30

Compositions and methods of engineered CRISPR-Cas9 systems using split-nexus Cas9-associated polynucleotides

#7081
20180245084
2018-08-30

COMPOSITIONS AND METHODS FOR ENHANCED INTESTINAL ABSORPTION OF CONJUGATED OLIGOMERIC COMPOUNDS

#7082
20180245083
2018-08-30

RNA INTERFERENCE MEDIATED INHIBITION OF GENE EXPRESSION USING CHEMICALLY MODIFIED SHORT INTERFERING NUCLEIC ACID (siNA)

#7083
20180245082
2018-08-30

PARENTAL RNAI SUPPRESSION OF CHROMATIN REMODELING GENES TO CONTROL COLEOPTERAN PESTS

#7084
20180245081
2018-08-30

Polycomb-associated non-coding RNAs

#7085
20180245080
2018-08-30

Methods and compositions to treat liver diseases and conditions

#7086
20180245079
2018-08-30

Methods and compositions for altering function and structure of chromatin loops and/or domains

#7087
20180245078
2018-08-30

Antisense oligonucleotides to treat Dystrophic Epidermolysis Bullosa

#7088
20180245077
2018-08-30

COMPOSITIONS AND METHODS FOR TREATING HYPERTRIGLYCERIDEMIA

#7089
20180245076
2018-08-30

MODULATION OF APOLIPOPROTEIN C-III (APOCIII) EXPRESSION IN LIPODYSTROPHY POPULATIONS

#7090
20180243450
2018-08-30

Humanized model of kidney and liver disorders

#7091
20180243446
2018-08-30

METHOD AND COMPOSITIONS FOR REMOVING DUPLICATED COPY NUMBER VARIAIONS (CNVS) FOR GENETIC DISORDERS AND RELATED USES

#7092
20180243436
2018-08-30

THERAPEUTIC CELL INTERNALIZING CONJUGATES

#7093
20180243433
2018-08-30

Block copolymers

#7094
20180243426
2018-08-30

Compounds and methods for trans-membrane delivery of molecules

#7095
20180243407
2018-08-30

Methods and compositions for eliciting an immune response against hepatitis B virus

#7096
20180238889
2018-08-23

THE SCANO-miR PLATFORM IDENTIFIES A DISTINCT CIRCULATING MICRORNA SIGNATURE FOR THE DIAGNOSIS OF DISEASE

#7097
20180237811
2018-08-23

Structuring fats and methods of producing structuring fats

#7098
20180237801
2018-08-23

METHODS AND COMPOSITIONS FOR RNA-DIRECTED TARGET DNA MODIFICATION AND FOR RNA-DIRECTED MODULATION OF TRANSCRIPTION

#7099
20180237787
2018-08-23

GENE EDITING OF PCSK9

#7100
20180237780
2018-08-23

UNA oligomers for therapeutics with prolonged stability

#7101
20180237779
2018-08-23

MiR-92 inhibitors and uses thereof

#7102
20180237778
2018-08-23

ANTISENSE DESIGN

#7103
20180237777
2018-08-23

ANTISENSE DESIGN

#7104
20180237776
2018-08-23

Methods and compositions for modlating apolipoprotein (A) expression

#7105
20180237775
2018-08-23

ANTISENSE OLIGONUCLEOTIDES AND USES THEREOF

#7106
20180237774
2018-08-23

METHODS OF SCREENING FOR RIBOSWITCHES AND ATTENUATORS

#7107
20180237773
2018-08-23

Splice-region antisense composition and method

#7108
20180237770
2018-08-23

Compositions and Methods of Nucleic Acid-Targeting Nucleic Acids

#7109
20180236104
2018-08-23

EXOSOME TRANSFER OF NUCLEIC ACIDS TO CELLS

#7110
20180235210
2018-08-23

ANTISENSE COMPOSITIONS TARGETING ERWINIA SPECIES AND METHODS OF USING THE SAME

#7111
20180230546
2018-08-16

Reagents and Methods for miRNA Expression Analysis and Identification of Cancer Biomarkers

#7112
20180230497
2018-08-16

METHODS AND COMPOSITIONS FOR RNA-DIRECTED TARGET DNA MODIFICATION AND FOR RNA-DIRECTED MODULATION OF TRANSCRIPTION

#7113
20180230496
2018-08-16

METHODS AND COMPOSITIONS FOR RNA-DIRECTED TARGET DNA MODIFICATION AND FOR RNA-DIRECTED MODULATION OF TRANSCRIPTION

#7114
20180230495
2018-08-16

METHODS AND COMPOSITIONS FOR RNA-DIRECTED TARGET DNA MODIFICATION AND FOR RNA-DIRECTED MODULATION OF TRANSCRIPTION

#7115
20180230491
2018-08-16

Method for expression of small RNA molecules within a cell

#7116
20180230470
2018-08-16

Compositions and methods for inhibiting gene expression of Hif2alpha

#7117
20180230469
2018-08-16

Method of treating pain with an antibody against netrin-4, UNC5B or neogenin

#7118
20180230468
2018-08-16

Treatment of atonal homolog 1 (ATOH1) related diseases by inhibition of natural antisense transcript to ATOH1

#7119
20180230467
2018-08-16

Brush polymer-assisted compaction of oligonucleotides

#7120
20180230466
2018-08-16

METHODS FOR TREATING TUMORS

#7121
20180230465
2018-08-16

METHODS AND COMPOSITIONS FOR MODULATING ALPHA-1-ANTITRYPSIN EXPRESSION

#7122
20180230207
2018-08-16

Notch inhibition in the treatment and prevention of nonalcoholic fatty liver disease

#7123
20180228919
2018-08-16

Bicistronic AAV vector for RNA interference in ALS

#7124
20180228830
2018-08-16

NUCLEIC ACID COMPLEX HAVING AT LEAST ONE BULGE STRUCTURE

#7125
20180228829
2018-08-16

ANTISENSE OLIGONUCLEOTIDES FOR THE TREATMENT OF LEBER CONGENITAL AMAUROSIS

#7126
20180223309
2018-08-09

COPI COATOMER GAMMA SUBUNIT NUCLEIC ACID MOLECULES THAT CONFER RESISTANCE TO COLEOPTERAN AND HEMIPTERAN PESTS

#7127
20180223300
2018-08-09

Methods and Materials for Producing Fruit of Altered Size

#7128
20180223295
2018-08-09

Methods and hybrids for targeted nucleic acid editing in plants using CRISPR/Cas systems

#7129
20180223286
2018-08-09

Interfering RNA molecules

#7130
20180223284
2018-08-09

Multimeric oligonucleotides having decreased kidney clearance

#7131
20180223283
2018-08-09

ANTISENSE FINGERLOOP RNAS AND USES THEREOF

#7132
20180223282
2018-08-09

Compositions and methods for modulating MECP2 expression

#7133
20180223281
2018-08-09

Structurally-enhanced miRNA inhibitor S-TuD

#7134
20180223280
2018-08-09

NUCLEIC ACID COMPLEX

#7135
20180223279
2018-08-09

THERAPEUTIC OLIGONUCLEOTIDES

#7136
20180223278
2018-08-09

Functionally-modified oligonucleotides and subunits thereof

#7137
20180223277
2018-08-09

Precursor miRNA and applications in tumor therapy thereof

#7138
20180223274
2018-08-09

Molecular sensor selection

#7139
20180222917
2018-08-09

Compositions and methods for treating leukemia

#7140
20180221479
2018-08-09

Agents for use in the treatment of glioma

#7141
20180221436
2018-08-09

Treatments of oxidative stress conditions

#7142
20180216135
2018-08-02

Nuclease with enhanced efficiency of genome editing

#7143
20180216130
2018-08-02

Nucleic acid molecules that control pathogens

#7144
20180216127
2018-08-02

Reducing levels of nicotinic alkaloids in plants

#7145
20180216122
2018-08-02

Diplospory gene

#7146
20180216117
2018-08-02

Engineered shell proteins for microcompartment shell electron transfer and catalysis

#7147
20180216116
2018-08-02

Antisense oligomers targeting PCSK9

#7148
20180216109
2018-08-02

MicroRNA-328 anti-sense composition and therapeutic use

#7149
20180216108
2018-08-02

Oligonucleotide compositions and methods thereof

#7150
20180216107
2018-08-02

OLIGONUCLEOTIDE COMPOSITIONS AND METHODS THEREOF

#7151
20180216106
2018-08-02

Oligonucleotides matching COL7A1 exon 73 for epidermolysis bullosa therapy

#7152
20180216105
2018-08-02

Biological control of coleopteran pests

#7153
20180216084
2018-08-02

HSD17B13 variants and uses thereof

#7154
20180214574
2018-08-02

Modified siRNA and pharmaceutical composition

#7155
20180214546
2018-08-02

MODULATION OF SRPX2-MEDIATED ANGIOGENESIS

#7156
20180214475
2018-08-02

microRNAS FOR THE TREATMENT OF HEART DISEASES

#7157
20180214474
2018-08-02

Methods and compositions for selecting siRNA of improved functionality

#7158
20180209979
2018-07-26

METHOD FOR INDIVIDUALIZED CANCER THERAPY

#7159
20180208934
2018-07-26

Base sequence for protein expression and method for producing protein using same

#7160
20180208931
2018-07-26

Methods and compositions for RNA-directed target DNA modification and for RNA-directed modulation of transcription

#7161
20180208930
2018-07-26

TREATMENT OF LIPID TRANSPORT AND METABOLISM GENE RELATED DISEASES BY INHIBITION OF NATURAL ANTISENSE TRANSCRIPT TO A LIPID TRANSPORT AND METABOLISM GENE

#7162
20180208929
2018-07-26

Treatment of reprogramming factor related diseases by inhibition of natural antisense transcript to a reprogramming factor

#7163
20180208928
2018-07-26

TOOLS AND METHODS USING MIRNA 182, 96 AND/OR 183 FOR TREATING PATHOLOGIES

#7164
20180208927
2018-07-26

Multi-targeted single entity conjugates

#7165
20180208926
2018-07-26

ANTISENSE OLIGONUCLEOTIDE INHIBITING ß2GPI EXPRESSION

#7166
20180208925
2018-07-26

Inhibition of microRNA-134 for the treatment of seizure-related disorders and neurologic injuries

#7167
20180208555
2018-07-26

Method of synthesis of an ionizable cationic lipid

#7168
20180208547
2018-07-26

Cationic lipids for therapeutic agent delivery formulations

#7169
20180207197
2018-07-26

OLIGONUCLEOTIDE DERIVATIVE

#7170
20180201955
2018-07-19

Targeted integration into the PPP1R12C locus

#7171
20180201936
2018-07-19

Polynucleotide agents targeting patatin-like phospholipase domain containing 3 (PNPLA3) and methods of use thereof

#7172
20180201935
2018-07-19

Fidgetin-like 2 as a target to enhance wound healing

#7173
20180201934
2018-07-19

Methods and compositions for selecting siRNA of improved functionality

#7174
20180201933
2018-07-19

Compounds for inducing anti-tumor immunity and methods thereof

#7175
20180201932
2018-07-19

Albumin production and cell proliferation

#7176
20180201931
2018-07-19

Treatment of adiponectin (ADIPOQ) related diseases by inhibition of natural antisense transcript to an adiponectin (ADIPOQ)

#7177
20180201930
2018-07-19

COMPOUNDS AND METHODS FOR MODULATING TARGET NUCLEAR AND SUB-NUCLEAR NUCLEIC ACID MOLECULES IN CELLS AND ANIMALS

#7178
20180201929
2018-07-19

Insulin-like growth factor binding protein, acid labile subunit (IGFALS) compositions and methods of use thereof

#7179
20180201928
2018-07-19

Micromirs

#7180
20180201927
2018-07-19

NOVEL PRECURSOR MIRNA AND APPLICATION THEREOF IN TUMOR TREATMENT

#7181
20180201913
2018-07-19

Engineered nucleic-acid targeting nucleic acids

#7182
20180201660
2018-07-19

ANTI-ANGIOGENIC VEGF-AX ISOFORM

#7183
20180200387
2018-07-19

Materials and methods for treatment of human genetic diseases including hemoglobinopathies

#7184
20180200281
2018-07-19

Control of coleopteran pests using RNA molecules

#7185
20180195137
2018-07-12

PEST CONTROL SYSTEM

#7186
20180195070
2018-07-12

Compositions and methods for inhibiting gene expression of LPA

#7187
20180195069
2018-07-12

Alpha-1 antitrypsin (AAT) RNAi agents, compositions including AAT RNAi agents, and methods of use

#7188
20180195068
2018-07-12

Methods for treating apolipoprotein E4-associated disorders

#7189
20180195067
2018-07-12

Compounds that target MYC microRNA responsive elements for the treatment of MYC-associated cancer

#7190
20180195066
2018-07-12

Methods for treating neurological disorders using a synergistic small molecule and nucleic acids therapeutic approach

#7191
20180195065
2018-07-12

Transgenic microalgae and use thereof as a feed for delivery of interfering RNA molecules

#7192
20180195064
2018-07-12

Therapeutic agent for a lung disease and/or method for screening for the same

#7193
20180195063
2018-07-12

DISCONTINUOUS OLIGONUCLEOTIDE LIGANDS

#7194
20180195062
2018-07-12

Pharmaceutical Composition

#7195
20180195058
2018-07-12

CRISPR/CAS-related methods and compositions for treating Leber's Congenital Amaurosis 10 (LCA10)

#7196
20180193484
2018-07-12

Nanoconjugates able to cross the blood-brain barrier

#7197
20180193471
2018-07-12

ß2GPI GENE EXPRESSION-SUPPRESSING NUCLEIC ACID CONJUGATE

#7198
20180193374
2018-07-12

Micro-RNA for the treatment of malignant solid tumors and metastasis

#7199
20180193344
2018-07-12

Nanocarriers and their processing for diagnostics and therapeutics

#7200
20180193279
2018-07-12

Diester and triester based low molecular weight, biodegradeable cationic lipids for oligonucleotide delivery