109164 ⎘
Structure or type of the nucleic acid; Chemical structure of the backbone with an inverted bond, e.g. a cap structure
RNA INTERFERENCE MEDIATED INHIBITION OF PROLIFERATION CELL NUCLEAR ANTIGEN (PCNA) GENE EXPRESSION USING SHORT INTERFERING NUCLEIC ACID (siNA)
#302RNA interference mediated inhibition of polycomb group protein EZH2 gene expression using short interfering nucleic acid (siNA)
#303RNA INTERFERENCE MEDIATED INHIBITION OF RAS GENE EXPRESSION USING SHORT INTERFERING NUCLEIC ACID (siNA)
#304RNA interference mediated inhibition of Stearoyl-CoA desaturase (SCD) gene expression using short interfering nucelic acid (siNA)
#305RNA interference mediated inhibition of MYC and/or MYB gene expression using short interfering nucleic acid (siNA)
#306RNA interference mediated inhibition of XIAP gene expression using short interfering nucleic acid (siNA)
#307RNA interference mediated inhibition of checkpoint kinase-1 (CHK-1) gene expression using short interfering nucleic acid (siNA)
#308Aptamers to the human IL-12 cytokine family and their use as autoimmune disease therapeutics
#309Metabolic profile directed aptamer medicinal chemistry
#310Stabilized immune modulatory RNA (SIMRA) compounds
#311Stabilized Aptamers to Platelet Derived Growth Factor and their Use as Oncology Therapeutics
#312MicroRNA and methods for inhibiting same
#313RNA Interference Mediated Inhibition of MAP Kinase Gene Expression or Expression of Genes Involved in MAP Kinase Pathway Using Short Interfering Nucleic Acid (SiNA)
#314RNA interference mediated inhibition of gene expression using chemically modified short interfering nucleic acid (siNA)
#315Nucleic Acid Ligands Specific to Immunoglobuline E and Their Use as Atopic Disease Therapeutics
#316Synthetic agonists of TLR9
#317High viscosity macromolecular compositions for treating ocular conditions
#318Aptamer-mediated intracellular delivery of oligonucleotides
#319Platelet derived growth factor (PDGF) nucleic acid ligand complexes
#320RNA interference mediated inhibition of hypoxia inducible factor 1 (HIF1) gene expression using short interfering nucleic acid (siNA)
#321Polycationic compositions for cellular delivery of polynucleotides
#322RNA interference mediated treatment of Alzheimer's disease using short interfering nucleic acid (siNA)
#323Modulation of immunostimulatory activity of immunostimulatory oligonucleotide analogs by positional chemical changes
#324Kits and methods for generating 5' capped RNA
#325Compounds and Methods for Rna Interference of the P65 Subunit of Nf-Kappa-B
#326Rna interference mediated inhibition of nogo and nogo receptor gene expression using short interfering nucleic acid (sina)
#327RNA interference mediated inhibition of gene expression using chemically modified short interfering nucleic acid (siNA)
#328RNA INTERFERENCE MEDIATED TREATMENT OF ALZHEIMER'S DISEASE USING SHORT INTERFERING NUCLEIC ACID (siNA)
#329Dbait and uses thereof
#330Rna interference mediated inhibition of xiap gene expression using short interfering nucleic acid (sina)
#331Oligonucleotide analogues incorporating 5-aza-cytosine therein
#332Modulation of immunostimulatory activity of immunostimulatory oligonucleotide analogs by positional chemical changes
#333Aptamer medicinal chemistry
#334Aptamers to the human IL-12 cytokine family and their use as autoimmune disease therapeutics
#335RNA interference mediated inhibition of 11 beta-hydroxysteroid dehydrogenase-1 (11 beta-HSD-1) gene expression using short interfering nucleic acid siNA
#336Aptamer therapeutics useful in the treatment of complement-related disorders
#337Enzymatic nucleic acid-mediated treatment of ocular diseases or conditions related to levels of vascular endothelial growth factor receptor (VEGF-R)
#338Rna interference mediated inhibition of gene expression using chemically modified short interfering nucleic acid (sina)
#339Modulation of gene expression associated with inflammation proliferation and neurite outgrowth using nucleic acid based technologies
#340Methods and compositions for treatment of tumors using nucleic acid ligands to platelet-derived growth factor
#341Double stranded compositions comprising a 3′-endo modified strand for use in gene modulation
#342Nucleic acid ligands specific to immunoglobulin E and their use as atopic disease therapeutics
#343RNA interference mediated inhibition of gene expression using chemically modified short interfering nucleic acid (siNA)
#344RNA interference mediated inhibition of gene expression using chemically modified short interfering nucleic acid (siNA)
#345RNA interference mediated inhibition of gene expression using chemically modified short interfering nucleic acid (siNA)
#346RNA interference mediated inhibition of gene expression using chemically modified short interfering nucleic acid (siNA)
#347RNA interference mediated inhibition of gene expression using chemically modified short interfering nucleic acid (siNA)
#348RNA interference mediated inhibition of gene expression using chemically modified short interfering nucleic acid (siNA)
#349Methods and compositions for treating ocular disorders
#350RNA interference mediated inhibition of gene expression using chemically modified short interfering nucleic acid (siNA)
#351RNA interference mediated ihibition of gene expression using chemically modified short interfering nucleic acid (siNA)
#352RNA interference mediated inhibition of gene expression using chemically modified short interfering nucleic acid (siNA)
#353RNA interference mediated inhibition of gene expression using chemically modified short interfering nucleic acid (siNA)
#354RNA interference mediated inhibition of gene expression using chemically modified short interfering nucleic acid (siNA)
#355RNA interference compositions and methods
#356Aptamers to von Willebrand Factor and their use as thrombotic disease therapeutics
#357Oligomeric compounds and compositions for use in modulation of pri-mirnas
#358RNA interference mediated inhibition of gene expression using chemically modified short interfering nucleic acid (siNA)
#359RNA interference mediated inhibition of gene expression using chemically modified short interfering nucleic acid (siNA)
#360Rna interference mediated treatment of alzheimer's disease using short interfering nucleic acid (sina)
#361RNA interference mediated inhibition of desmoglein gene expression using short interfering nucleic acid (siNA)
#362Tissue-specific and pathogen-specific toxic agents, ribozymes, dnazymes and antisense oligonucleotides, and methods of use thereof
#363RNA interference mediated inhibition of gene expression using chemically modified short interfering nucleic acid (siNA)
#364RNA interference mediated inhibition of gene expression using chemically modified short interfering nucleic acid (siNA)
#365RNA interference mediated inhibition of gene expression using chemically modified short interfering nucleic acid (siNA)
#366RNA interference mediated inhibition of gene expression using chemically modified short interfering nucleic acid (siNA)
#367RNA interference mediated inhibition of vascular endothelial growth factor and vascular endothelial growth factor receptor gene expression using short interfering nucleic acid (siNA)
#368Delivery of polynucleotide agents to the central nervous system
#369Aptamers to the human IL-12 cytokine family and their use as autoimmune disease therapeutics
#370Aptamers to von Willebrand Factor and their use as thrombotic disease therapeutics
#371Oligonucleotide inhibitors of MBD2/DNA demethylase and uses thereof
#372Method for prevention or treatment of diseases or disorders related to excessive formation of vascular tissue or blood vessels
#373Enzymatic nucleic acid treatment of diseases or conditions related to levels of IKK-gamma and PKR
#374Modulation of oligonucleotide CpG-mediated immune stimulation by positional modification of nucleosides
#375RNA interference mediated inhibition of cyclin dependent kinase-2 (CDK2) gene expression using short interfering nucleic acid (siNA)
#376Modulation of immunostimulatory activity of immunostimulatory oligonucleotide analogs by positional chemical changes
#377Modulation of immunostimulatory activity of immunostimulatory oligonucleotide analogs by positional chemical changes
#378RNA interference mediated inhibition of MAP kinase gene expression or expression of genes involved in MAP kinase pathway using short interfering nucleic acid (siNA)
#379Effective and stable DNA enzymes
#380Aptamer therapeutics useful in the treatment of complement-related disorders
#381Aptamer-mediated intracellular delivery of therapeutic oligonucleotides
#382Tenascin-C nucleic acid ligands
#383Methods and materials for treating human papillomavirus infections
#384Controlled modulation of the pharmacokinetics and biodistribution of aptamer therapeutics
#385RNA interference mediated inhibition of protein tyrosine phosphatase-1B (PTP-1B) gene expression using short interfering nucleic acid (siNA)
#386RNA interference mediated inhibtion of protein tyrosine phosphatase-1B (PTP-1B) gene expression using short interfering nucleic acid (siNA)
#387Aptamer therapeutics useful in the treatment of complement-related disorders
#388RNA interference mediated inhibition of RAS gene expression using short interfering nucleic acid (siNA)
#389RNA interference mediated inhibition of placental growth factor gene expression using short interfering nucleic acid (sINA)
#390RNA interference mediated inhibition of interleukin and interleukin receptor gene expression using short interfering nucleic acid (siNA)
#391Oligomeric compounds and compositions for use in modulation of small non-coding RNAs
#392RNA interference mediated inhibition of NOGO and NOGO receptor gene expression using short interfering RNA
#393RNA interference mediated inhibition of stearoyl-CoA desaturase (SCD) gene expression using short interfering nucleic acid (siNA)
#394RNA interference mediated inhibition of matrix metalloproteinase 13 (MMP13) gene expression using short interfering nucleic acid (siNA)
#395RNA interference mediated inhibition of platelet derived growth factor (PDGF) and platelet derived growth factor receptor (PDGFR) gene expression using short interfering nucleic acid (siNA)
#396Method and reagent for the treatment of diseases or conditions related to levels of vascular endothelial growth factor receptor
#397MicroRNA and methods for inhibiting same
#398RNA interference mediated inhibition of vascular endothelial growth factor and vascular endothelial growth factor receptor gene expression using short interfering nucleic acid (siNA)
#399Vascular therapeutics
#400Polycationic compositions for cellular delivery of polynucleotides
#401Nucleic acid mediated inhibition of enterococcus infection and cytolysin toxin activity
#402RNA interference mediated treatment of Alzheimer's disease using short interfering nucleic acid (siNA)
#403RNA interference mediated inhibition of vascular cell adhesion molecule (VCAM) gene expression using short interfering nucleic acid (siNA)
#404Three component chimeric antisense oligonucleotides
#405RNA interference mediated inhibition of GRB2 associated binding protein (GAB2) gene expression using short interfering nucleic acis (siNA)
#406RNA interference mediated treatment of polyglutamine (polyQ) repeat expansion diseases using short interfering nucleic acid (siNA)
#407RNA interference mediated inhibition of intercellular adhesion molecule (ICAM) gene expression using short interfering nucleic acid (siNA)
#408RNA interference mediated inhibition of NF-Kappa B / REL-A gene expression using short interfering nucleic acid (siNA)
#409RNA interference mediated inhibition of NOGO and NOGO receptor gene expression using short interfering nucleic acid (siNA)
#410RNA interference mediated inhibition of interleukin and interleukin receptor gene expression using short interfering nucleic acid (SINA)
#411RNA interference mediated inhibition of protein kinase C alpha (PKC-alpha) gene expression using short interfering nucleic acid (siNA)
#412RNA interference mediated inhibition of GPRA and AAA1 gene expression using short interfering nucleic acid (siNA)
#413RNA interference mediated inhibition of cholinergic muscarinic receptor (CHRM3) gene expression using short interfering nucleic acid (siNA)
#414RNA interference mediated inhibition of protein tyrosine phosphatase type IVA (PRL3) gene expression using short interfering nucleic acid (siNA)
#415RNA interference mediated inhibition of B-cell CLL/Lymphoma-2 (BCL-2) gene expression using short interfering nucleic acid (siNA)
#416RNA interference mediated inhibition of epidermal growth factor receptor (EGFR) gene expression using short interfering nucleic acid (siNA)
#417Chemically modified double stranded nucleic acid molecules
#418RNA interference mediated inhibition of cholesteryl ester transfer protein (CEPT) gene expression using short interfering nucleic acid (siNA)
#419RNA interference mediated inhibition of vascular endothelial growth factor and vascular endothelial growth factor receptor gene expression using short interfering nucleic acid (siNA)
#420RNA interference mediated inhibition of 5-alpha reductase and androgen receptor gene expression using short interfering nucleic acid (siNA)
#421RNA interference mediated inhibition of ADAM33 gene expression using short interfering nucleic acid (siNA)
#422RNA interference mediated inhibition of platelet-derived endothelial cell growth factor (ECGF1) gene expression using short interfering nucleic acid (siNA)
#423RNA interference mediated inhibition of type 1 insulin-like growth factor receptor gene expression using short interfering nucleic acid (siNA)
#424RNA interference mediated inhibition of cyclin D1 gene expression using short interfering nucleic acid (siNA)
#425RNA interference mediated inhibition of polycomb group protein EZH2 gene expression using short interfering nucleic acid (siNA)
#426RNA interference mediated inhibition of chromosome translocation gene expression using short interfering nucleic acid (siNA)
#427RNA interference mediated inhibition of angiopoietin gene expression using short interfering nucleic acid (siNA)
#428RNA interference mediated inhibition of gastric inhibitory polypeptide (GIP) and gastric inhibitory polypeptide receptor (GIPR) gene expression using short interfering nucleic acid (siNA)
#429RNA interference mediated inhibition of Myc and/or Myb gene expression using short interfering nucleic acid (siNA)
#430RNA interference mediated inhibition 5-alpha reductase and androgen receptor gene expression using short interfering nucleic acid (siNA)
#431RNA interference mediated inhibition of proliferating cell nuclear antigen (PCNA) gene expression using short interfering nucleic acid (siNA)
#432RNA interference mediated inhibition of telomerase gene expression using short interfering nucleic acid (siNA)
#433RNA interference mediated inhibition of early growth response gene expression using short interfering nucleic acid (siNA)
#434RNA interference mediated inhibition of MDR P-glycoprotein gene expression using short interfering nucleic acid (siNA)
#435RNA interference mediated inhibition of vascular endothelial growth factor and vascular endothelial growth factor receptor gene expression using short interfering nucleic acid (siNA)
#436Antisense oligonucleotides against tenascin for the treating of vitiligo
#437RNA interference mediated inhibition of interleukin and interleukin receptor gene expression using short interfering nucleic acid (SINA)
#438RNA interference mediated target discovery and target validation using short interfering nucleic acid (siNA)
#439RNA interference mediated treatment of Parkinson disease using short interfering nucleic acid (siNA)
#440RNA interference mediated inhibition of alpha-1 antitrypsin (AAT) gene expression using short interfering nucleic acid (siNA)
#441RNA interference mediated inhibition of G72 and D-amino acid oxidase (DAAO) gene expression using short interfering nucleic acid (siNA)
#442RNA interference mediated inhibition of wingless gene expression using short interfering nucleic acid (siNA)
#443RNA interference mediated inhibition of CXCR4 gene expression using short interfering nucleic acid (siNA)
#444RNA interference mediated inhibition of acetyl-CoA-carboxylase gene expression using short interfering nucleic acid (siNA)
#445RNA interference mediated inhibition of TRPM7 gene expression using short interfering nucleic acid (siNA)
#446RNA interference mediated inhibition of myostatin gene expression using short interfering nucleic acid (siNA)
#447Vascular therapeutics
#448RNA interference mediated inhibition of FAS and FASL gene expression using short interfering nucleic acid (siNA)
#449RNA mediated inhibition connexin gene expression using short interfering nucleic acid (siNA)
#450Tissue-specific and pathogen-specific ribozymes
#451RNA interference mediated inhibition of platelet-derived endothelial cell growth factor (ECGF1) gene expression using short interfering nucleic acid (siNA)
#4525'-and 3'-capped aptamers and uses therefor
#453RNA interference mediated inhibition of Fos gene expression using short interfering nucleic acid (siNA)
#454RNA interference mediated inhibition of vascular endothelial growth factor and vascular endothelial growth factor receptor gene expression using short interfering nucleic acid (siNA)
#455RNA interference mediated inhibtion of tyrosine phosphatase-1B (PTP-1B) gene expression using short interfering nucleic acid (siNA)
#456RNA interference mediated inhibition of vascular endothelial growth factor and vascular endothelial growth factor receptor gene expression using short interfering nucleic acid (siNA)
#457Use of double-stranded ribonucleic acid for inducing cell lysis
#458Platelet derived growth factor (PDGF) nucleic acid ligand complexes
#459RNA interference mediated inhibition of gene expression using chemically modified short interfering nucleic acid (SiNA)
#460Modulation of immunostimulatory activity of immunostimulatory oligonucleotide analogs by positional chemical changes
#461Methods for identifying aptamer regulators