ClassID:

109164

C12N2310/317 - CPC Classification

Classification description:

Structure or type of the nucleic acid; Chemical structure of the backbone with an inverted bond, e.g. a cap structure

Recent Application in this class:
#1
20260139251
2026-05-21

RNAi Agents for Inhibiting Expression of Mucin 5AC (MUC5AC), Compositions Thereof, and Methods of Use

#2
20260092283
2026-04-02

COMPOSITIONS AND METHODS FOR THE TREATMENT OF COMPLICATIONS AND DISORDERS RELATING TO VON WILLEBRAND FACTOR

#3
20260085314
2026-03-26

CONJUGATED OLIGONUCLEOTIDE COMPOUNDS, METHODS OF MAKING AND USES THEREOF

#4
20260043025
2026-02-12

RNAi Agents And Compositions for Inhibiting Expression of Apolipoprotein C-III (APOC3)

#5
20260009036
2026-01-08

INHIBITORS OF EXPRESSION AND/OR FUNCTION

#6
20260007766
2026-01-08

COMPOSITIONS AND METHODS OF TREATING MUSCLE ATROPHY AND MYOTONIC DYSTROPHY

#7
20250388620
2025-12-25

EFFICIENT METHOD FOR MAKING HIGHLY PURIFIED 5’- CAPPED OLIGONUCLEOTIDES

#8
20250320502
2025-10-16

RNAI CONSTRUCTS FOR INHIBITING PNPLA3 EXPRESSION AND METHODS OF USE THEREOF

#9
20250243485
2025-07-31

Targeting Ligands For Therapeutic Compounds

#10
20250223597
2025-07-10

LIPID CONJUGATES FOR THE DELIVERY OF THERAPEUTIC AGENTS TO CNS TISSUE

#11
20250215043
2025-07-03

RNA CAP ANALOGS AND METHODS OF USE

#12
20250195676
2025-06-19

COMPOSITIONS AND METHODS OF TREATING MUSCLE ATROPHY AND MYOTONIC DYSTROPHY

#13
20250163417
2025-05-22

COMPOSITIONS AND METHODS FOR IMPROVING STRAND BIASED

#14
20250066791
2025-02-27

RNA INTERFERENCE MEDIATED INHIBITION OF PROLYL HYDROXYLASE DOMAIN 2 (PHD2) GENE EXPRESSION USING SHORT INTERFERING NUCLEIC ACID (SINA)

#15
20250000889
2025-01-02

METHODS FOR TREATING OR PREVENTING OPHTHALMOLOGICAL CONDITIONS

#16
20240318183
2024-09-26

MODULATION OF PREKALLIKREIN (PKK) EXPRESSION

#17
20240318178
2024-09-26

VON WILLEBRAND FACTOR (VWF)-TARGETING AGENTS AND METHODS OF USING THE SAME

#18
20240318171
2024-09-26

CRISPR-BASED COMPOSITIONS AND METHODS OF USE

#19
20240229075
2024-07-11

IMPROVED NUCLEIC ACID SEQUENCE FOR CELL TYPE SPECIFIC EXPRESSION

#20
20240191240
2024-06-13

DEFINED MULTI-CONJUGATES OLIGONUCLEOTIDES

#21
20240175033
2024-05-30

TMEM173 saRNA Compositions and Methods of Use

#22
20240141351
2024-05-02

ALPHA-1 ANTITRYPSIN (AAT) RNAI AGENTS, COMPOSITIONS INCLUDING AAT RNAI AGENTS, AND METHODS OF USE

#23
20240132895
2024-04-25

GLYCOGEN SYNTHASE KINASE 3 ALPHA (GSK3 ALPHA) iRNA COMPOSITIONS AND METHODS OF USE THEREOF

#24
20240102008
2024-03-28

CONJUGATED OLIGONUCLEOTIDE COMPOUNDS, METHODS OF MAKING AND USES THEREOF

#25
20240043840
2024-02-08

CHEMICALLY MODIFIED CRISPR-CAS13 GUIDE RNAS

#26
20240035029
2024-02-01

RNA COMPOSITIONS AND METHODS FOR INHIBITING LIPOPROTEIN(A)

#27
20230407311
2023-12-21

NUCLEIC ACIDS CONTAINING ABASIC NUCLEOTIDES

#28
20230364123
2023-11-16

Methods for treating or preventing ophthalmological conditions

#29
20230364122
2023-11-16

METHODS FOR TREATING OR PREVENTING OPHTHALMOLOGICAL CONDITIONS

#30
20230332148
2023-10-19

DISCONTINUOUS OLIGONUCLEOTIDE LIGANDS

#31
20230330271
2023-10-19

THROMBUS IMAGING APTAMERS AND METHODS OF USING SAME

#32
20230323350
2023-10-12

RNAi Agents And Compositions for Inhibiting Expression of Apolipoprotein C-III (APOC3)

#33
20230323344
2023-10-12

Polynucleotides containing a morpholino linker

#34
20230295215
2023-09-21

NOVEL MRNA 5'-END CAP ANALOGS MODIFIED WITHIN PHOSPHATE RESIDUES, RNA MOLECULE INCORPORATING THE SAME, USES THEREOF AND METHOD OF SYNTHESIZING RNA MOLECULE OR PEPTIDE

#35
20230201363
2023-06-29

Compositions and methods of treating muscle atrophy and myotonic dystrophy

#36
20230201362
2023-06-29

Compositions and methods of treating muscle atrophy and myotonic dystrophy

#37
20230174989
2023-06-08

Methods and Compositions for the ADAR-Mediated Editing of ABCA4

#38
20230093170
2023-03-23

Nucleic Acid Compounds for Binding to Complement Component 3 Protein

#39
20230047754
2023-02-16

COMPOSITIONS AND METHODS OF TREATING MUSCLE ATROPHY AND MYOTONIC DYSTROPHY

#40
20230002767
2023-01-05

RNAi Agents for Inhibiting Expression of Mucin 5AC (MUC5AC), Compositions Thereof, and Methods of Use

#41
20230002760
2023-01-05

CRISPR/CAS-RELATED METHODS, COMPOSITIONS AND COMPONENTS

#42
20220380772
2022-12-01

RNA interference mediated inhibition of prolyl hydroxylase domain 2 (PHD2) gene expression using short interfering nucleic acid (siNA)

#43
20220380770
2022-12-01

SHORT INTERFERING NUCLEIC ACID (siNA) MOLECULES AND USES THEREOF FOR CORONAVIRUS DISEASES

#44
20220290148
2022-09-15

Defined multi-conjugates oligonucleotides

#45
20220290143
2022-09-15

Products and compositions

#46
20220275366
2022-09-01

RNA INTERFERENCE MEDIATED INHIBITION OF GENE EXPRESSION USING CHEMICALLY MODIFIED SHORT INTERFERING NUCLEIC ACID (SINA)

#47
20220220484
2022-07-14

METHODS AND COMPOSITIONS OF SHORT SMALL HAIRPIN RNAS AND MICRORNAS FOR WOUND HEALING

#48
20220220473
2022-07-14

PROTEIN TRANSLATIONAL CONTROL

#49
20220204978
2022-06-30

PROTEIN TRANSLATIONAL CONTROL

#50
20220175813
2022-06-09

Methods for treating or preventing ophthalmological conditions

#51
20220170023
2022-06-02

Modulation of prekallikrein (PKK) expression

#52
20220170015
2022-06-02

Alpha-1 antitrypsin (AAT) RNAi agents, compositions including AAT RNAi agents, and methods of use

#53
20220133900
2022-05-05

Compositions and methods of treating muscle atrophy and myotonic dystrophy

#54
20220106388
2022-04-07

HIGH VISCOSITY MACROMOLECULAR COMPOSITIONS FOR TREATING OCULAR CONDITIONS

#55
20220096647
2022-03-31

COMPOSITIONS AND METHODS OF TREATING MUSCLE ATROPHY AND MYOTONIC DYSTROPHY

#56
20220090074
2022-03-24

HNF4a saRNA compositions and methods of use

#57
20220062434
2022-03-03

Compositions and methods of treating muscle atrophy and myotonic dystrophy

#58
20220056454
2022-02-24

RNAi Agents for Inhibiting Expression of 17beta-HSD Type 13 (HSD17B13), Compositions Thereof, and Methods of Use

#59
20220056441
2022-02-24

RNA INTERFERENCE MEDIATED INHIBITION OF GENE EXPRESSION USING CHEMICALLY MODIFIED SHORT INTERFERING NUCLEIC ACID (SINA)

#60
20220040323
2022-02-10

Compositions and methods of treating muscle atrophy and myotonic dystrophy

#61
20220040322
2022-02-10

Compositions and methods of treating muscle atrophy and myotonic dystrophy

#62
20220033817
2022-02-03

Targeting Ligands

#63
20220033434
2022-02-03

ANDROGEN RECEPTOR NUCLEIC ACIDS AND USES THEREOF

#64
20220017906
2022-01-20

RNAI CONSTRUCTS FOR INHIBITING PNPLA3 EXPRESSION AND METHODS OF USE THEREOF

#65
20220010310
2022-01-13

An lncRNA integrates a DNA-PK-mediated DNA damage response and vascular senescence

#66
20220008550
2022-01-13

Compositions and methods of treating muscle atrophy and myotonic dystrophy

#67
20220000900
2022-01-06

Oligonucleotide Analogues Incorporating 5-Aza-Cytosine Therein

#68
20210369757
2021-12-02

Methods for treating or preventing ophthalmological conditions

#69
20210332361
2021-10-28

Aptamer therapeutics useful in the treatment of complement-related disorders

#70
20210330692
2021-10-28

CCR7 aptamers and uses thereof

#71
20210292763
2021-09-23

COMPOSITIONS AND METHODS FOR THE TREATMENT OF COMPLICATIONS AND DISORDERS RELATING TO VON WILLEBRAND FACTOR

#72
20210238602
2021-08-05

RNAi Agents And Compositions for Inhibiting Expression of Angiopoietin-Like 3 (ANGPTL3), And Methods Of Use

#73
20210238594
2021-08-05

Compositions and methods for improving strand biased

#74
20210222170
2021-07-22

Von Willebrand Factor (VWF)-targeting agents and methods of using the same

#75
20210189394
2021-06-24

Targeting ligands for therapeutic compounds

#76
20210187116
2021-06-24

Compositions and methods of treating muscle atrophy and myotonic dystrophy

#77
20210180053
2021-06-17

SYNTHETIC RNAS AND METHODS OF USE

#78
20210108212
2021-04-15

RNAi constructs for inhibiting ASGR1 expression and methods of use thereof

#79
20200405877
2020-12-31

Compositions and methods of treating muscle atrophy and myotonic dystrophy

#80
20200399639
2020-12-24

Detection of microbial endotoxins in oral samples using aptamers

#81
20200353102
2020-11-12

Thrombus imaging aptamers and methods of using same

#82
20200332299
2020-10-22

RNA interference mediated inhibition of prolyl hydroxylase domain 2 (PHD2) gene expression using short interfering nucleic acid (SINA)

#83
20200318117
2020-10-08

Influenza-activated constructs and methods of use thereof

#84
20200299690
2020-09-24

RNAi agents and compositions for inhibiting expression of apolipoprotein C-III (APOC3)

#85
20200255827
2020-08-13

Stabilized HNF4A saRNA compositions and methods of use

#86
20200255826
2020-08-13

HNF4A saRNA compositions and methods of use

#87
20200216849
2020-07-09

Stem-loop compositions and methods for inhibiting factor D

#88
20200215092
2020-07-09

Oligonucleotide analogues incorporating 5-aza-cytosine therein

#89
20200208149
2020-07-02

Alpha-1 antitrypsin (AAT) RNAi agents, compositions including AAT RNAi agents, and methods of use

#90
20200165612
2020-05-28

Compositions and methods for the treatment of complications and disorders relating to Von Willebrand Factor

#91
20200138847
2020-05-07

Myostatin iRNA compositions and methods of use thereof

#92
20200063133
2020-02-27

Products and compositions

#93
20190390202
2019-12-26

Methods and compositions of short small hairpin RNAs and microRNAs for wound healing

#94
20190381087
2019-12-19

METHODS FOR TREATING OR PREVENTING OPHTHALMOLOGICAL CONDITIONS

#95
20190309306
2019-10-10

RNAi constructs for inhibiting ASGR1 expression and methods of use thereof

#96
20190298847
2019-10-03

Compositions and methods of treating muscle atrophy and myotonic dystrophy

#97
20190262383
2019-08-29

CCR7 aptamers and uses thereof

#98
20190256849
2019-08-22

Targeting ligands

#99
20190233827
2019-08-01

Modulation of prekallikrein (PKK) expression

#100
20190233821
2019-08-01

RNA interference mediated inhibition of gene expression using chemically modified short interfering nucleic acid (siNA)

#101
20190218553
2019-07-18

Von Willebrand Factor (VWF)—targeting agents and methods of using the same

#102
20190218546
2019-07-18

MRNA CAP ANALOGS WITH MODIFIED PHOSPHATE LINKAGE

#103
20190211368
2019-07-11

Trinucleotide mRNA cap analogs

#104
20190211333
2019-07-11

Targeting Ligands For Therapeutic Compounds

#105
20190194658
2019-06-27

RNA INTERFERENCE MEDIATED INHIBITION OF GENE EXPRESSION USING CHEMICALLY MODIFIED SHORT INTERFERING NUCLEIC ACID (siNA)

#106
20190185858
2019-06-20

Aptamer therapeutics useful in the treatment of complement-related disorders

#107
20190136230
2019-05-09

GENETICALLY ENGINEERED CELLS AND METHODS OF MAKING THE SAME

#108
20190085331
2019-03-21

Defined multi-conjugate oligonucleotides

#109
20190078089
2019-03-14

RNAi agents and compositions for inhibiting expression of angiopoietin-like 3 (ANGPTL3), and methods of use

#110
20190078088
2019-03-14

RNAi agents and compositions for inhibiting expression of apolipoprotein C-III (APOC3)

#111
20190078087
2019-03-14

Polynucleotides containing a morpholino linker

#112
20190062746
2019-02-28

RNA interference mediated inhibition of gene expression using chemically modified short interfering nucleic acid (siNA)

#113
20190062744
2019-02-28

Oligomeric compounds and compositions for use in modulation of small non-coding RNAs

#114
20190040385
2019-02-07

Double-stranded oligonucleotide molecules targeting p53 and methods of use thereof

#115
20190032056
2019-01-31

Stem-loop compositions and methods for inhibiting factor D

#116
20190023732
2019-01-24

Oligonucleotides

#117
20190017047
2019-01-17

Methods for modulating Ataxin 2 expression

#118
20190010497
2019-01-10

RNA INTERFERENCE MEDIATED INHIBITION OF GENE EXPRESSION USING CHEMICALLY MODIFIED SHORT INTERFERING NUCLEIC ACID (siNA)

#119
20180346913
2018-12-06

Chemically modified multifunctional short interfering nucleic acid molecules that mediate RNA interference

#120
20180340179
2018-11-29

Compositions with improved intravitreal half-life and uses thereof

#121
20180305696
2018-10-25

METHODS AND COMPOSITIONS FOR PREVENTING ISCHEMIA REPERFUSION INJURY IN ORGANS

#122
20180305393
2018-10-25

Phosphate replacement mRNA cap analogs

#123
20180291055
2018-10-11

Phosphate replacement MRNA cap analogs

#124
20180273944
2018-09-27

Oligonucleotide-based inhibitors comprising locked nucleic acid motif

#125
20180237783
2018-08-23

Methods and compositions of short small hairpin RNAS and microRNAS for wound healing

#126
20180195071
2018-07-12

RNA interference mediated inhibition of hepatitis B Virus (HBV) gene expression using short interfering nucleic acid (siNA)

#127
20180179523
2018-06-28

CRISPR-BASED COMPOSITIONS AND METHODS OF USE

#128
20180127757
2018-05-10

Use of aptamers in therapy and/or diagnosis of autoimmune diseases

#129
20180117182
2018-05-03

Thrombus imaging aptamers and methods of using same

#130
20180112213
2018-04-26

CRISPR/CAS-RELATED METHODS, COMPOSITIONS AND COMPONENTS

#131
20180100154
2018-04-12

RNA interference mediated inhibition of prolyl hydroxylase domain 2 (PHD2) gene expression using short interfering nucleic acid (siNA)

#132
20180064819
2018-03-08

Targeting ligands

#133
20180055869
2018-03-01

COMPOSITIONS AND METHODS FOR MODULATING RNA

#134
20180044671
2018-02-15

DOUBLE-STRANDED OLIGONUCLEOTIDE MOLECULES TO P53 AND METHODS OF USE THEREOF

#135
20180030446
2018-02-01

APTAMER THERAPEUTICS USEFUL IN THE TREATMENT OF COMPLEMENT-RELATED DISORDERS

#136
20180030441
2018-02-01

siRNA compounds comprising terminal substitutions

#137
20180023085
2018-01-25

IMMUNE REGULATORY OLIGONUCLEOTIDE (IRO) COMPOUNDS TO MODULATE TOLL-LIKE RECEPTOR BASED IMMUNE RESPONSE

#138
20180010128
2018-01-11

Oligomeric compounds and compositions for use in modulation of small non-coding RNAs

#139
20180010125
2018-01-11

Double-stranded oligonucleotide molecules to DDIT4 and methods of use thereof

#140
20170342416
2017-11-30

RNA interference mediated inhibition of gene expression using chemically modified short interfering nucleic acid (siNA)

#141
20170335327
2017-11-23

Methods and compositions for preventing ischemia reperfusion injury in organs

#142
20170328909
2017-11-16

Aptamers and diagnostic methods for detecting the EGF receptor

#143
20170314030
2017-11-02

Beta-catenin nucleic acids and uses thereof

#144
20170314026
2017-11-02

Modulation of prekallikrein (PKK) expression

#145
20170283816
2017-10-05

RNA interference mediated inhibition of gene expression using chemically modified short interfering nucleic acid (siNA)

#146
20170268002
2017-09-21

Oligomeric compounds and compositions for use in modulation of small non-coding RNAs

#147
20170253875
2017-09-07

Targeting ligands for therapeutic compounds

#148
20170211083
2017-07-27

RNA interference mediated inhibition of gene expression using chemically modified short interfering nucleic acid (siNA)

#149
20170175113
2017-06-22

Methods for modulating Ataxin 2 expression

#150
20170166895
2017-06-15

Nucleic acid compounds for binding to complement component 3 protein

#151
20170130226
2017-05-11

Aptamers against EGFR and therapeutic uses thereof

#152
20170107518
2017-04-20

RNA oligonucleotide and immune system enhancer comprising same

#153
20170107511
2017-04-20

Oligonucleotide end caps

#154
20170081665
2017-03-23

METHODS AND COMPOSITIONS FOR PREVENTING ISCHEMIA REPERFUSION INJURY IN ORGANS

#155
20170044545
2017-02-16

APTAMER FOR BONDING TO AUTOTAXIN AND INHIBITING BIOLOGICAL ACTIVITY OF AUTOTAXIN, AND USE FOR SAME

#156
20170044536
2017-02-16

CRISPR-based compositions and methods of use

#157
20170044535
2017-02-16

CRISPR-based compositions and methods of use

#158
20170037402
2017-02-09

Oligomeric compounds and compositions for use in modulation of small non-coding RNAs

#159
20170035794
2017-02-09

Oligonucleotide analogues incorporating 5-aza-cytosine therein

#160
20170002359
2017-01-05

Modulation of prekallikrein (PKK) expression

#161
20160355820
2016-12-08

Aptamer construct

#162
20160333356
2016-11-17

Oligonucleotide modulators of the toll-like receptor pathway

#163
20160326526
2016-11-10

Oligonucleotide-based inhibitors comprising locked nucleic acid motif

#164
20160304879
2016-10-20

Double-stranded RNA compounds to CASP2 and uses thereof

#165
20160298123
2016-10-13

RNA INTERFERENCE MEDIATED INHIBITION OF PROLYL HYDROXYLASE DOMAIN 2 (PHD2) GENE EXPRESSION USING SHORT INTERFERING NUCLEIC ACID (SINA)

#166
20160257962
2016-09-08

RNA INTERFERENCE MEDIATED INHIBITION OF ISOCITRATE DEHYDROGENASE (IDH1) GENE EXPRESSION

#167
20160244756
2016-08-25

Formats for organic compounds for use in RNA interference

#168
20160215287
2016-07-28

Immune regulatory oligonucleotide (IRO) compounds to modulate toll-like receptor based immune response

#169
20160208258
2016-07-21

miR-92 inhibitors and uses thereof

#170
20160177304
2016-06-23

CRISPR-based compositions and methods of use

#171
20160160218
2016-06-09

Use of aptamers in therapy and/or diagnosis of autoimmune diseases

#172
20160130296
2016-05-12

Oligonucleotide analogues incorporating 5-aza-cytosine therein

#173
20160108399
2016-04-21

Modulation of HSP47 expression

#174
20160076031
2016-03-17

Phosphorous-linked oligomeric compounds and their use in gene modulation

#175
20160060629
2016-03-03

Synthetic mimics of miR-124

#176
20160017329
2016-01-21

Oligomeric compounds and compositions for use in modulation of small non-coding RNAs

#177
20150376622
2015-12-31

Influenza-activated constructs and methods of use thereof

#178
20150337304
2015-11-26

Oligomeric compounds and compositions for use in modulation of small non-coding RNAs

#179
20150322433
2015-11-12

Post-synthetic orthogonal amidation plus metal catalyzed azide-alkyne cycloaddition click chemistry on siRNA

#180
20150267200
2015-09-24

RNA interference mediated inhibition of gene expression using chemically modified short interfering nucleic acid (siNA)

#181
20150267194
2015-09-24

Double-stranded oligonucleotide molecules to DDIT4 and methods of use thereof

#182
20150259675
2015-09-17

Short interfering ribonucleic acid (siRNA) for oral administration

#183
20150232847
2015-08-20

TARGETING OLIGONUCLEOTIDES AND RELATED METHODS FOR MODULATING FXN RNA

#184
20150232844
2015-08-20

METHODS FOR MODULATING RNA USING 5' TARGETING OLIGONUCLEOTIDES

#185
20150203845
2015-07-23

Double-stranded oligonucleotide molecules to P53 and methods of use thereof

#186
20150159158
2015-06-11

Aptamer therapeutics useful in the treatment of complement-related disorders

#187
20150159154
2015-06-11

Oligonucleotide compounds comprising non-nucleotide overhangs

#188
20150152412
2015-06-04

siRNA compounds comprising terminal substitutions

#189
20150086996
2015-03-26

Aptamers and diagnostic methods for detecting the EGF receptor

#190
20150017163
2015-01-15

Methods for Treating or Preventing Ophthalmological Conditions

#191
20140371439
2014-12-18

Double-stranded RNA compounds to CASP2 and uses thereof

#192
20140336370
2014-11-13

Oligomeric compounds and compositions for use in modulation of small non-coding RNAs

#193
20140329882
2014-11-06

Oligomeric compounds and compositions for use in modulation of small non-coding RNAS

#194
20140296501
2014-10-02

Aptamers and diagnostic methods for detecting the EGF receptor

#195
20140235701
2014-08-21

NGF aptamer and application thereof

#196
20140235695
2014-08-21

Modulation of HSP47 expression

#197
20140227778
2014-08-14

MicroRNA and methods for inhibiting same

#198
20140128587
2014-05-08

Nucleic acid modulators of glycoprotein VI

#199
20140121364
2014-05-01

Oligomeric compounds and compositions for use in modulation of small non-coding RNAs

#200
20140107182
2014-04-17

Synthetic mimics of miR-34

#201
20140094503
2014-04-03

RNA interference mediated inhibition of isocitrate dehydrogenase (IDH1) gene expression

#202
20140057963
2014-02-27

Oligomeric compounds and compositions for use in modulation of small non-coding RNAS

#203
20140004100
2014-01-02

Immune regulatory oligonucleotide (IRO) compounds to modulate toll-like receptor based immune response

#204
20130237589
2013-09-12

Aptamer therapeutics useful in the treatment of complement-related disorders

#205
20130236536
2013-09-12

Oligonucleotide analogues incorporating 5-aza-cytosine therein

#206
20130230923
2013-09-05

Short interfering ribonucleic acid (siRNA) for oral administration

#207
20130165500
2013-06-27

RNA interference mediated inhibition of prolyl hydroxylase domain 2 (PHD2) gene expression using short interfering nucleic acid (siNA)

#208
20130035369
2013-02-07

DOUBLE STRAND COMPOSITIONS COMPRISING DIFFERENTIALLY MODIFIED STRANDS FOR USE IN GENE MODULATION

#209
20130035368
2013-02-07

Oligonucleotide compounds comprising non-nucleotide overhangs

#210
20130012567
2013-01-10

RNA interference mediated inhibition of gene expression using chemically modified short interfering nucleic acid (siNA)

#211
20120322860
2012-12-20

Aptamer therapeutics useful in the treatment of complement-related disorders

#212
20120288933
2012-11-15

Synthetic mimics of miR-34

#213
20120283319
2012-11-08

Method of inhibiting miR-33 using a modified oligonucleotide

#214
20120283309
2012-11-08

Sirna compounds comprising terminal substitutions

#215
20120276627
2012-11-01

Synthetic mimics of MIR-124

#216
20120183530
2012-07-19

Stabilized immune modulatory RNA (SIMRA) compounds

#217
20120157514
2012-06-21

Oligomeric compounds and compositions for use in modulation of small non-coding RNAs

#218
20120148664
2012-06-14

CHEMICAL MODIFICATIONS MOTIFS FOR MIRNA INHIBITORS AND MIMETICS

#219
20120142101
2012-06-07

Oligonucleotide end caps

#220
20120128699
2012-05-24

Immune regulatory oligonucleotide (IRO) compounds to modulate toll-like receptor based immune response

#221
20120122216
2012-05-17

Oligomeric compounds and compositions for use in modulation of small non-coding RNAs

#222
20120100136
2012-04-26

METHODS FOR TREATING OR PREVENTING OPHTHALMOLOGICAL DISEASES

#223
20120077265
2012-03-29

MicroRNA and methods for inhibiting same

#224
20120035248
2012-02-09

Method for inhibiting the activity of mir-155

#225
20120029054
2012-02-02

RNA Interference Mediated Inhibition of GATA Binding Protein 3 (GATA3) Gene Expression Using Short Intefering Nucleic Acid (siNA)

#226
20120029053
2012-02-02

Short interfering ribonucleic acid (siRNA) for oral administration

#227
20120029052
2012-02-02

Short interfering ribonucleic acid (siRNA) for oral administration

#228
20120022143
2012-01-26

RNA Interference Mediated Inhibition of the Thymic Stromal Lymphopoietin (TSLP) Gene Expression Using Short Interfering Nucliec Acid (siNA)

#229
20120022142
2012-01-26

RNA Interference Mediated Inhibition of Signal Transducer and Activator of Transcription 1 (STAT1) Gene Expression Using Short Interfering Nucleic Acid (siNA)

#230
20120022139
2012-01-26

Short interfering ribonucleic acid (siRNA) for oral administration

#231
20120016011
2012-01-19

RNA Interference Mediated Inhibition of Connective Tissue Growth Factor (CTGF) Gene Expression Using Short Interfering Nucleic Acid (siNA)

#232
20120016010
2012-01-19

RNA Interference Mediated Inhibition of BTB and CNC Homology 1, Basic Leucine Zipper Transcription Factor 1 (BACH1) Gene Expression Using Short Interfering Nucleic Acid (siNA)

#233
20120010272
2012-01-12

RNA Interference Mediated Inhibition of Apoptosis Signal-Regulating Kinase 1 (ASK1) Gene Expression Using Short Interfering Nucleic Acid (siNA)

#234
20120004282
2012-01-05

RNA Interference Mediated Inhibition of the Intercellular Adhesion Molecule 1 (ICAM-1) Gene Expression Using Short Interfering Nucleic Acid (siNA)

#235
20120004281
2012-01-05

RNA Interference Mediated Inhibition of the Nerve Growth Factor Beta Chain (NGFB) Gene Expression Using Short Interfering Nucleic Acid (siNA)

#236
20120004280
2012-01-05

RNA interference mediated inhibition of the FCεR1α gene

#237
20110301220
2011-12-08

RNA interference mediated inhibition of gene expression using chemically modified short interfering nucleic acid (siNA)

#238
20110301219
2011-12-08

RNA interference mediated inhibition of gene expression using chemically modified short interfering nucleic acid (siNA)

#239
20110288154
2011-11-24

RNA Interference Mediated Inhibition of Epithelial Sodium Channel (ENaC) Gene Expression Using Short Interfering Nucleic Acid (siNA)

#240
20110263683
2011-10-27

RNA interference mediated inhibition of gene expression using chemically modified short interfering nucleic acid (siNA)

#241
20110224277
2011-09-15

Oligomeric compounds and compositions for use in modulation of small non-coding RNAS

#242
20110178157
2011-07-21

Modulation of HSP47 expression

#243
20110165226
2011-07-07

INFLUENZA CAP-LEADER SEQUENCE

#244
20110135669
2011-06-09

SYNTHETIC AGONISTS OF TLR9

#245
20110105591
2011-05-05

siRNA compounds for inhibiting NRF2

#246
20110065772
2011-03-17

TREATMENT OF RHEUMATOID ARTHRITIS

#247
20110060027
2011-03-10

Aptamer therapeutics useful in the treatment of complement-related disorders

#248
20110059067
2011-03-10

MODULATION OF OLIGONUCLEOTIDE CPG-MEDIATED IMMUNE STIMULATION BY POSITIONAL MODIFICATION OF NUCLEOSIDES

#249
20110046206
2011-02-24

DOUBLE STRAND COMPOSITIONS COMPRISING DIFFERENTIALLY MODIFIED STRANDS FOR USE IN GENE MODULATION

#250
20110038871
2011-02-17

CCR2 INHIBITORS FOR TREATING CONDITIONS OF THE EYE

#251
20100311812
2010-12-09

RNA interference mediated inhibition of intercellular adhesion molecule (ICAM) gene expression using short interfering nucleic acid (siNA)

#252
20100311808
2010-12-09

Methods, compositions and drug delivery systems for intraocular delivery of siRNA molecules

#253
20100305191
2010-12-02

RNA INTERFERENCE MEDIATED INHIBITION OF ADENOSINE A1 RECEPTOR (ADORA1) GENE EXPRESSION USING SHORT INTERFERING RNA

#254
20100267813
2010-10-21

Method for inhibiting the activity of mir-155

#255
20100261231
2010-10-14

Dinucleotide MRNA cap analogs

#256
20100249215
2010-09-30

Oligomeric compounds and compositions for use in modulation of pri-miRNAs

#257
20100240730
2010-09-23

RNA Interference Mediated Inhibition of Gene Expression Using Chemically Modified Short Interfering Nucleic Acid (siNA)

#258
20100228018
2010-09-09

RNA INTERFERENCE MEDIATED INHIBITION OF PROLIFERATING CELL NUCLEAR ANTIGEN (PCNA) GENE EXPRESSION USING SHORT INTERFERING NUCLEIC ACID (siNA)

#259
20100215729
2010-08-26

Oligonucleotide analogues incorporating 5-aza-cytosine therein

#260
20100215642
2010-08-26

Synthetic RNA-based agonists of TLR7

#261
20100197763
2010-08-05

RNA Interference Mediated Inhibition of Cyclic Nucleotide Type 4 Phosphodiesterase (PDE4B) Gene Expression Using Short Interfering Nucleic Acid (siNA)

#262
20100184825
2010-07-22

RNA interference mediated inhibition of protein tyrosine phosphatase-1B (PTP-1B) gene expression using short interfering nucleic acid (siNA)

#263
20100168208
2010-07-01

RNA interference mediated treatment of alzheimer's disease using short interfering nucleic acid (siNA)

#264
20100160617
2010-06-24

Nuclease-resistant RNA aptamer inhibiting replication of hepatitis C virus replicon

#265
20100152278
2010-06-17

RNA Interference Mediated Inhibition of Cyclic Nucleotide Type 4 Phosphodiesterase (PDE4B) Gene Expression Using Short Interfering Nucleic Acid (siNA)

#266
20100144846
2010-06-10

Oligoribonucleotides and uses thereof

#267
20100137405
2010-06-03

RNA Interference Mediated Inhibition of Cyclic Nucleotide Type 4 Phosphodiesterase (PDE4B) Gene Expression Using Short Interfering Nucleic Acid (siNA)

#268
20100120895
2010-05-13

RNA Interference Mediated Inhibition of Cyclic Nucleotide Type 4 Phosphodiesterase (PDE4B) Gene Expression Using Short Interfering Nucleic Acid (siNA)

#269
20100099743
2010-04-22

RNA interference mediated inhibition of checkpoint kinase-1 (CHK-1) gene expression using short interfering nucleic acid (siNA)

#270
20100036107
2010-02-11

RNA INTERFERENCE COMPOSITIONS AND METHODS

#271
20100029922
2010-02-04

Platelet derived growth factor (PDGF) nucleic acid ligand complexes

#272
20100015707
2010-01-21

Short interfering ribonucleic acid (siRNA) with improved pharmacological properties

#273
20100004432
2010-01-07

Aptamer against midkine and use thereof

#274
20090317907
2009-12-24

Oligomeric compounds and compositions for use in modulation of small non-coding RNAs

#275
20090299045
2009-12-03

RNA Interference Mediated Inhibition Of Interleukin and Interleukin Gene Expression Using Short Interfering Nucleic Acid (siNA)

#276
20090298174
2009-12-03

Oligomeric compounds and compositions for use in modulation of small non-coding RNAs

#277
20090291907
2009-11-26

Oligomeric compounds and compositions for use in modulation of small non-coding RNAs

#278
20090291906
2009-11-26

Oligomeric compounds and compositions for use in modulation of small non-coding RNAs

#279
20090286969
2009-11-19

Oligomeric Compounds And Compositions For Use In Modulation Of Small Non-Coding RNAs

#280
20090281164
2009-11-12

RNA interference mediated inhibition of respiratory syncytial virus (RSV) expression using short interfering nucleic acid (siNA)

#281
20090275729
2009-11-05

MicroRNA and methods for inhibiting same

#282
20090264636
2009-10-22

Conjugates and compositions for cellular delivery

#283
20090264506
2009-10-22

DELIVERY OF POLYNUCLEOTIDE AGENTS TO THE CENTRAL NERVOUS SYSTEM

#284
20090253772
2009-10-08

RNA interference mediated inhibition of CXCR4 gene expression using short interfering nucleic acid (siNA)

#285
20090247613
2009-10-01

RNA INTERFERENCE MEDIATED INHIBITION OF B-CELL CLL/LYMPHOMA-2 (BCL2) GENE EXPRESSION USING SHORT INTERFERING NUCLEIC ACID (siNA)

#286
20090247606
2009-10-01

RNA Interference Mediated Inhibition of Adenosine A1 Receptor (ADORA1) Gene Expression Using Short Interfering Nucleic Acid (siNA)

#287
20090239931
2009-09-24

RNA INTERFERENCE MEDIATED INHIBITION OF PROTEIN TYROSINE PHOSPHATASE-1B (PTP-1B) GENE EXPRESSION USING SHORT INTERFERING NUCLEIC ACID (siNA)

#288
20090203766
2009-08-13

vWF aptamer formulations and methods for use

#289
20090192105
2009-07-30

RNA INTERFERENCE MEDIATED INHIBITION OF INTERCELLULAR ADHESION MOLECULE (ICAM) GENE EXPRESSION USING SHORT INTERFERING NUCELIC ACID (siNA)

#290
20090192104
2009-07-30

RNA interference mediated inhibition of hypoxia inducible factor 1 (HIF1) gene expression using short interfering nucleic acid (siNA)

#291
20090170197
2009-07-02

Nucleic Acid-Mediated Treatment of Diseases or Conditions Related to Levels of Vascular Endothelial Growth Factor Receptor (VEGF-R)

#292
20090162349
2009-06-25

METHOD FOR PREVENTION OR TREATMENT OF DISEASES OR DISORDERS RELATED TO EXCESSIVE FORMATION OF VASCULAR TISSUE OR BLOOD VESSELS

#293
20090156541
2009-06-18

DBAIT and uses thereof

#294
20090156528
2009-06-18

RNA interference mediated inhibition of hepatitis C virus (HCV) gene expression using short interfering nucleic acid (siNA)

#295
20090149643
2009-06-11

Aptamers to von Willebrand factor and their use as thrombotic disease therapeutics

#296
20090149408
2009-06-11

RNA interference mediated inhibition of telomerase gene expression using short interfering nucleic acid (siNA)

#297
20090149407
2009-06-11

RNA interference mediated treatment of Alzheimer's disease using short interfering nucleic acid (siNA)

#298
20090137513
2009-05-28

RNA Interference Mediated Inhibition of Acetyl-CoA-Carboxylase Gene Expression Using Short Interfering Nucleic Acid (siNA)

#299
20090137512
2009-05-28

RNA interference mediated inhibition of cyclin D1 gene expression using short interfering nucleic acid (siNA)

#300
20090137511
2009-05-28

RNA interference mediated inhibition of placental growth factor gene expression using short interfering nucleic acid (SINA)